Digital Commons Network^™

Jrsm 3900: Visual Media (Syllabus), Garrett Pilgrim

Journalism and Strategic Media Syllabi Archive

No abstract provided.

Jrsm 3900: Visual Media (Syllabus), Ruoxu Wang

Journalism and Strategic Media Syllabi Archive

No abstract provided.

Jrsm 3900: Visual Media (Syllabus), Ruoxu Wang

Journalism and Strategic Media Syllabi Archive

No abstract provided.

Jrsm 3900: Visual Media (Syllabus), Michael Robinson

Journalism and Strategic Media Syllabi Archive

No abstract provided.

Jrsm 3900: Visual Media (Syllabus), Michael Robinson

Journalism and Strategic Media Syllabi Archive

No abstract provided.

Together With Tosha Newsletter, Winter 2019, Tennessee. Department Of Labor & Workforce Development.

TOSHA Newsletter

No abstract provided.

No.76 An Order Renaming The Rocky Fork State Park As The Lamar Alexander Rocky Fork State Park, Bill Haslam

Executive Orders

No abstract provided.

Office Of Criminal Justice Programs Annual Report Fy 2017/2018, Tennessee. Department Finance & Administration.

Office of Criminal Justice Programs

No abstract provided.

2017 Tennessee Census Of Fatal Occupational Injuries, The Survey Of Occupational Injuries And Illnesses, Tennessee. Department Of Labor & Workforce Development.

Occupational Injuries

No abstract provided.

Tennessee's Economy 2018 Reference Guide, Tennessee. Department Of Labor & Workforce Development.

Tennessee's Economy

No abstract provided.

Effects Of Canagliflozin On Renal And Urinary Angiotensin Converting Enzyme 2 (Ace2) And Neprilysin (Nep) In Db/Db Diabetic Mice, Unmesha Hemant Thanekar

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Diabetes is one of the major causes of chronic kidney disease (CKD) which could lead to end-stage renal disease. Angiotensin-II (Ang-II), a major bioactive peptide of renin angiotensin system (RAS) plays a pivotal role in the pathogenesis and progression of diabetic nephropathy. The reno-degenerative effects of Ang-II can be partially counteracted by Ang (1-7). Therefore, Ang (1-7) forming enzymes, angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP), are hypothesized to have reno-protective effects. In our previous studies, we have demonstrated increased renal shedding of ACE2 and NEP in the urine of type-2 diabetic mice which was attenuated by normalizing hyperglycemia …

Space Dynamics Laboratory Payload Challenge: Autonomous Water Sampling Uav, Thomas Wheeler, Zachary Williams, Joseph Stack

Williams Honors College, Honors Research Projects

The following report has been completed over the course of the Fall 2018 and Spring 2019 semesters at The University of Akron by Joseph P. Stack (Aerospace Systems Engineering), Thomas J. Wheeler (Mechanical Engineering) and Zachary M. Williams (Mechanical Engineering). The purpose of this project was to create a payload system for the Akronauts Rocket Design Team to use at the Intercollegiate Rocket Engineering Competition (IREC) Spaceport America Cup. The Competition as a challenge that is sponsored by Space Dynamics Laboratory specifically regarding payload systems. The challenge in very open-ended and allows student to identify their own scientific experiment and …

Automatic Range Finding Bow Sight, Garrett Gill, Dillon Denny, Cory Verba

Williams Honors College, Honors Research Projects

With the growing popularity of archery, a system designed to help an archer achieve the best shot possible becomes necessary. The Automatic Range Finding Bow Sight is a system that consists of a single pin sight controlled by a servo motor. The servo motor controls the sight pin by rotating a drive wheel that will move the pin up or down. The sight pin movement is based on a reading obtained by a built-in rangefinder and speed data input by the user. This data will then be compared to programmed lookup tables in order to find the appropriate pin position. …

Investigating Alternative Measures Of Functional Recovery In Rat Sciatic Nerve Injury, Mariah L. Costa, Rebecca K. Willits

Williams Honors College, Honors Research Projects

There is a pressing need for advancements in peripheral nerve repair techniques and functional recovery evaluation methods. The rat sciatic nerve injury model is a well examined model for peripheral nerve repair. One measure of functional recovery after nerve damage, the sciatic functional index (SFI), fails in the presence of self-mutilation, toe contracture, and other abnormalities in gait. In this IACUC approved study, the sciatic nerve was severed in four experimental groups (n=5). The nerves were repaired with Arginylglycylaspartic acid-poly(ε-caprolactone) (RGD-PCL) peptide functionalized nanofibers, non-functionalized PCL control nanofibers, an isograft, and a negative control empty conduit. Video walking track analysis …

Lack Of Vaccination Risks, Abigail Sebunia

Williams Honors College, Honors Research Projects

This paper is a study regarding how vaccination rates are related to the number of measles cases that occur in a particular state. First, I will review the history of vaccines and the motivations for the refusals of this medical procedure. In addition, I will examine the various regulations regarding vaccinations and which states allow non-medical exemptions for religious or personal reasons. Within my analysis, I will provide examples of recent outbreaks to represent the extent of this current dilemma. Furthermore, I will offer potential solutions to mitigate measles outbreaks and the science regarding Herd Immunity Thresholds (HIT) to limit …

Optimization Of Conditions For Production Of Mechanically Strong Suckerin Protein Hydrogels, Autumn Furniss

Williams Honors College, Honors Research Projects

Hydrogels are polymer networks with a large water content. Uses include biomedical applications like drug delivery, wound dressing, and more. Current natural hydrogels lack mechanical robustness. Squid ringed teeth (completely protein) have a modulus comparable to thermoplastics; adding this to hydrogels could improve modulus while maintaining biocompatibility.

Three experiments were performed: Hofmeister solubility study, SRT powder additive, and SRT aqueous solution. The first showed that LiCl solution without acetic acid dissolved the most SRT; overall LiCl dissolved more than all others. SRT as a powder additive increased the modulus of the hydrogels, however the error in the measurements make it …

Synthesis Of Polyurethane From Sustainable Sources, Jovan Jevric

Williams Honors College, Honors Research Projects

The most common method of polyurethanes involves a reaction between various petroleum-based isocyanates and a polyol along with a catalyst; all of which have a negative impact on environmental and human health. The objective of this research project is to eliminate or mitigate the risks and hazards associated with the production and degradation of polyurethane. Hexamethylene diisocyanate isocyanurates (3HDI) are one of the most common isocyanates used in the polyurethane processing industry. 3HDI contains numerous toxins, and it has a negative impact on the environment and human health¹. It has been found that there are other compounds that …

Optimization Of Primary Cilia Detection In Musculoskeletal Tissue, Ragen Engel

Williams Honors College, Honors Research Projects

The objective of this research project was to optimize a laboratory technique for visualizing primary cilia in musculoskeletal tissue of young swine, specifically the growth plate of long bones. This was accomplished through varying fixation procedures, antigen retrieval methods, antibody concentrations, and incubation times. By varying these parameters, a reproducible procedure was developed to examine the primary cilia in multiple tissues including ligament, fascia, and growth plate. This experiment introduced variances in fixation methods, with methanol or formalin. Paraffin and frozen embedding techniques were also varied for comparison with regards to cilia visualization. Results from the acetylated alpha tubulin (aTUB) …

Rocket Telemetry System, Monica Lacek, Clark Bryant Iii, David Dalvin, Nicholas Wolgamott

Williams Honors College, Honors Research Projects

The goal of this research project is to design a system for the Akronauts Rocket Design Team which will transmit flight data in real-time to a ground station. The data will be collected from various sensors (altitude, acceleration, GPS, etc). This data will be transmitted wirelessly and in real-time to a receiving station. Calculations and visualizations will be taken from the data, which will help the team improve their rocket designs. Additionally, GPS data will be useful to locate the rocket post-flight. Challenges will include the need for the system to transmit over the range of the rocket’s flight and …

Effects Of Acute Hypoxia On Danio Rerio, Karly Crail

Williams Honors College, Honors Research Projects

The purpose of this research experiment was to determine the effects of acute hypoxia on the embryonic zebrafish (Danio rerio) cardiovascular system and assess the critical oxygen level at which embryonic function is compromised. This goal was achieved by exposing embryos to decreasing oxygen concentrations, (6.0 mg/L-0 mg/L) and observing the heart under an inverted microscope. Data analysis was conducted to determine end systolic volume, end diastolic volume, stroke volume, heart rate, and cardiac output. It was hypothesized that hypoxia would stimulate cardiac activity, because in early developmental stages, tissues are supplied with oxygen through bulk diffusion, and …

Climate Change As A Hazard In Emergency Management, Christen Swayer

Williams Honors College, Honors Research Projects

This project will provide a basic overview of hazards, a scientific overview of climate change, examine evidence used to document climate change, investigate how the public and private sectors are impacted by climate change, and determine if states are preparing for this hazard. Sources such as the National Oceanic and Atmospheric Administration (NOAA), the National Weather Service (NWS), and Climate Impact Lab will be consulted to determine if it would be beneficial to implement changes to prepare for the worsening effects of climate change. The methodology for this project will include quantitative climate data for temperature extremes and trends, hurricanes, …

Immersive Rehearsal In A Simulated Environment (Irise), Cassandra Clouse

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Recent advancements in virtual environment (VE) technology and the growth of VE use in treating and training individuals are opening up new possibilities for rehearsal in safe and rich environments. Research has shown that VEs can be used to treat those with Post Traumatic Stress Disorder (PTSD), but very little research has been done to suggest good guidelines for creating an effective environment. This research was conducted to help inform the design of systems that let veterans rehearse potentially stressful experiences in a safe environment before having to physically step into that environment. We investigated responses to specific design components …

Differential Microrna Expression In Barrett's Esophagus Correlates With Regulation Of Posterior Homeotic Genes, Reilly June Clark

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Barrett’s Esophagus (BE) is characterized by the appearance of an intestinal-like epithelium in the distal esophagus. The molecular mechanisms behind BE development are unknown. BE is often preceded by Gastroesophageal Reflux Disease (GERD) and predisposes patients to esophageal adenocarcinoma (EAC). Due to the high mortality rate associated with EAC, BE patients are continuously monitored through upper endoscopy with biopsy for progression to low grade dysplasia (LGD), high grade dysplasia, and EAC. This monitoring technique poses numerous risks, so alternative surveillance and diagnostic techniques for BE pathogenesis are continually studied. microRNA biomarkers in BE pathogenesis may provide alternative means of diagnosis …

Hierarchical Carbon Structures With Vertically- Aligned Nanotube Carpets For Oil-Water Separation Under Different Conditions, Kimia Kiaei

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The primary purpose of this study is to investigate the role of surface nano-structuring in fluid separation. It is hypothesized that hierarchical carbon structures consisting of aligned carbon nanotube arrays strongly adhered to the surface of porous carbon solids such as fabric and foam, can be used for separation of polar and non-polar fluids by selective wettability of one fluid and rejection of another. The vertically-aligned carbon nanotube arrays, as synthesized, possess super hydrophobicity demonstrated by high water contact angle on their surfaces. On the other hand, they are incredibly oleophilic, showing a high affinity to adsorb oil. These properties …

Kinetics Of Microvesicle Particle Release In Keratinocytes, Pariksha Thapa

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Microvesicle particles (MVPs) are subcellular particles that could be involved in inter-cellular communication because they carry various bioactive substances including cytokines. Previous studies from our lab has shown that that the lipid mediator Platelet-activating Factor (1-alkyl-2-acetyl-glycerophosphocholine; PAF) and ultraviolet B radiation (UVB) enhances the release of MVP in various cell types like primary keratinocytes, epithelial cell lines, and murine skin. We hypothesized that there may be synergistic increases in MVP release after combination of treatment of keratinocytes with UVB and PAF agonist (CPAF)/phorbol ester (PMA). The combination treatment significantly increases MVP and cytokine release at 4 to 8 hours time …

Social Buffering By Unfamiliar Adult Males In Periadolescent Guinea Pigs: The Effects On Hpa Axis Activity And Fos Induction In The Medial Prefrontal Cortex, Alexander Bertke

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In the guinea pig, the ability of the mother’s presence to buffer hypothalamic-pituitary- adrenal (HPA) axis activation in her young during exposure to stressful stimuli has been well documented. Under similar testing conditions, other conspecifics (littermates, other adult females) are less effective in doing so. The effect does seem to wane with age but is still present to a significant degree in offspring approaching adolescence. However, we recently observed that an unfamiliar adult male buffered HPA axis activation and increased Fos expression in the prefrontal cortex of preweaning infants exposed to a novel enclosure at both 60 and 120 minutes …

Virtual Experiments And Simulations In The Science Classroom, Nicole Merchant

Williams Honors College, Honors Research Projects

The main goal of this paper is to analyze the use of virtual experiments and simulations within the science classroom. This analysis will be completed by first reviewing the learning theories in education. Then I will specifically analyze virtual experiments and how they are used in the science classroom. At the time of this study I had the privilege of completing my student teaching experience in a high school science classroom. This gave me the ability to have direct contact with students in order to observe their interest and engagement with simulations as well as their learning throughout the semester. …

Antitumor Properties Of Imidazolium Salts, Jenna Frantz

Williams Honors College, Honors Research Projects

This is the final write-up for an honors research project for the University of Akron Williams Honors College. Synthesis of novel imidazolium salts was conducted. Following synthesis of imidazolium salts, the stability of the compound was tested at 37°C over a 72-hour period to give preliminary information about drug stability in vivo. 2D NMR was also conducted to confirm the structure of TPP-1. The student wrote an experimental protocol for the use of C57BL/6 mice and performed the online CITI training by the IRB to prepare to work with animals in a study of the antitumor properties of imidazolium salts …

M1 Melanopsin Ganglion Cells In The ​Mus Musculus​ Retina Are Similar In Shape And Size, Geoffrey K. Sarpong

Williams Honors College, Honors Research Projects

An M1 melanopsin retinal ganglion cell (mRGC) is a subtype of the five melanopsin ganglion cells. The M1-type mRGC is distributed on the dorsal retina of a mouse and has an extensively overlapping dendritic network in both the sublamina a (OFF) and sublamina b (ON) layers of the inner plexiform layer. In the dorsal retina, the M1-type mRGCs are distinct and asymmetric.

The aim of this study was to examine the morphological similarity (shape and size) of M1-type mRGCs. The study traced 20 neurons in the first four months of a glaucoma retina of a DBA mouse, made measurements of …

Bad World: The Negativity Bias In International Politics, D. D. P. Johnson, Dominic Tierney

Political Science Faculty Works

A major puzzle in international relations is why states privilege negative over positive information. States tend to inflate threats, exhibit loss aversion, and learn more from failures than from successes. Rationalist accounts fail to explain this phenomenon, because systematically overweighting bad over good may in fact undermine state interests. New research in psychology, however, offers an explanation. The “negativity bias” has emerged as a fundamental principle of the human mind, in which people's response to positive and negative information is asymmetric. Negative factors have greater effects than positive factors across a wide range of psychological phenomena, including cognition, motivation, emotion, …