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Coding Sequences Of Sarcoplasmic Reticulum Calcium Atpase Regulatory Peptides And Expression Of Calcium Regulatory Genes In Recurrent Exertional Rhabdomyolysis, Stephanie J. Valberg, Kaitlin Soave, Zoe J. Williams, Sudeep Perumbakkam, Melissa Schott, Carrie J. Finno, Jessica L. Petersen, Clara Fenger, Joseph M. Autry, David D. Thomas

Department of Animal Science: Faculty Publications

Background: Sarcolipin (SLN), myoregulin (MRLN), and dwarf open reading frame (DWORF) are transmembrane regulators of the sarcoplasmic reticulum calcium transporting ATPase (SERCA) that we hypothesized played a role in recurrent exertional rhabdomyolysis (RER).

Objectives: Compare coding sequences of SLN, MRLN, DWORF across species and between RER and control horses. Compare expression of muscle Ca²⁺ regulatory genes between RER and control horses.

Animals: Twenty Thoroughbreds (TB), 5 Standardbreds (STD), 6 Quarter Horses (QH) with RER and 39 breed-matched controls.

Methods: Sanger sequencing of SERCA regulatory genes with comparison of amino acid (AA) …

Yes-Associated Protein 1 Is Required For Proliferation And Function Of Bovine Granulosa Cells In Vitro, Michele R. Plewes, Xiaoying Hou, Pan Zhang, Aixin Liang, Guohua Hua, Jennifer R. Wood, Andrea S. Cupp, Xiangmin Lv, Cheng Wang, John S. Davis

Department of Animal Science: Faculty Publications

Yes-associated protein 1 (YAP1) is a major component of the Hippo signaling pathway. Although the exact extracellular signals that control the Hippo pathway are currently unknown, increasing evidence supports a critical role for the Hippo pathway in embryonic development, regulation of organ size, and carcinogenesis. Granulosa cells (GCs) within the ovarian follicle proliferate and produce steroids and growth factors, which facilitate the growth of follicle and maturation of the oocyte.We hypothesize that YAP1 plays a role in proliferation and estrogen secretion of GCs. In the current study, we examined the expression of the Hippo signaling pathway in bovine ovaries and …

Postnatal Β2 Adrenergic Treatment Improves Insulin Sensitivity In Lambs With Iugr But Not Persistent Defects In Pancreatic Islets Or Skeletal Muscle, Dustin T. Yates, Leticia E. Camacho, Amy C. Kelly, Leah V. Steyn, Melissa A. Davis, Andrew T. Antolic, Miranda J. Anderson, Ravi Goyal, Ronald E. Allen, Klearchos K. Papas, William W. Hay Jr, Sean W. Limesand

Department of Animal Science: Faculty Publications

Placental insufficiency causes intrauterine growth restriction (IUGR) and disturbances in glucose homeostasis with associated β adrenergic receptor (ADRβ) desensitization. Our objectives were to measure insulin-sensitive glucose metabolism in neonatal lambs with IUGR and to determine whether daily treatment with ADRβ2 agonist and ADRβ1/β3 antagonists for 1 month normalizes their glucose metabolism. Growth, glucose-stimulated insulin secretion (GSIS) and glucose utilization rates (GURs) were measured in control lambs, IUGR lambs and IUGR lambs treated with adrenergic receptor modifiers: clenbuterol atenolol and SR59230A (IUGR-AR). In IUGR lambs, islet insulin content and GSIS were less than …

Ractopamine Hcl Improved Cardiac Hypertrophy But Not Poor Growth, Metabolic Inefficiency, Or Greater White Blood Cells Associated With Heat Stress In Concentrate-Fed Lambs, Rebecca M. Swanson, Kristin A. Beede, Micayla D. Freeman, Morgan L. Eggleston, Ty B. Schmidt, Jessica L. Petersen, Dustin T. Yates

Department of Animal Science: Faculty Publications

Heat stress decreases livestock performance and well-being (Hahn, 1999; Nienaber and Hahn, 2007), causes metabolic dysfunction that decreases growth efficiency (O’Brien et al., 2010), and alters cardiovascular function (Crandall et al., 2008). Each year, heat stress costs the livestock industry up to $2.5 billion (St-Pierre et al., 2003). Ractopamine HCl acts as a nutrient repartitioning agent (Beermann, 2002); classified as a β adrenergic agonist (βAA), it shares pharmacological properties with adrenaline (Beermann, 2002). βAA increase muscle mass and decreases fat deposition through unknown mechanisms (Beermann, 2002). In feedlot cattle, they increase growth efficiency and improve carcass yield and merit (Scramlin …

Body Composition Estimated By Bioelectrical Impedance Analyses Is Diminished By Prenatal Stress In Neonatal Lambs And By Heat Stress In Feedlot Wethers, Rachel L. Gibbs, Caitlin N. Cadaret, Rebecca M. Swanson, Kristin A. Beede, Robert J. Posont, Ty B. Schmidt, Jessica Lynn Petersen, Dustin T. Yates

Department of Animal Science: Faculty Publications

Body composition correlates to carcass value in livestock, which makes the ability to accurately estimate body composition in the live animal beneficial (Berg and Marchello, 1994). Bioelectrical impedance analysis (BIA) is a clinical tool used to assess body composition in humans (Lukaski et al., 1985), but its use in livestock has been minimal. Lean and fat content contribute to profitability for livestock producers, and poor body composition can be caused by stress that occurs either during in utero development (De Blasio et al., 2007) or during postnatal growth (Boyd et al., 2015). Maternal hyperthermia-induced placental insufficiency (Brown et al., 2015) …

Farm Animals Are Important Biomedical Models, Debora L. Hamernik

Department of Animal Science: Faculty Publications

This issue of Animal Frontiers, “Farm animals are im- portant biomedical models,” describes several examples in which cattle, sheep, pigs, or chickens provide an excellent physiological model for studies related to human health or disease (Figure 1). While previous reports have discussed the use of domestic animals as dual-purpose models that benefit agricultural and biomedical research (Ireland et al., 2008), this issue of Animal Frontiers provides additional and novel examples of the value of farm animals for biomedical re- search. Because farm animals are larger in size than labora- tory species, scientists are able to collect larger volumes and …

The Heritability Of Pampiniform Plexus Vessel Size And Varicocoele In Boars, Tasha R. Gruhot, Lea A. Rempel, Matthew L. Spangler, Stephen D. Kachman, Benny E. Mote

Department of Animal Science: Faculty Publications

Ultrasonography was used to capture a coronal–sagittal image of the veins of the pampiniform plexus (PP) and the testicular artery of 327 maternal‐line boars at approximately 6 months of age at the University of Nebraska—Lincoln. Varicocoele was diagnosed by two methods. Method 1 diagnosed varicocoele when the average vessel area on one side of the scrotum was 1.5 times larger than the average vessel area on the other side of the scrotum. Method 2 diagnosed varicocoele when the average vessel area on one side of the scrotum of a boar was 1.5 times larger than the average vessel on the …

Adaptation Strategies: Ruminants, John B. Gaughan, Veerasamy Sejian, Terry L. Mader, Frank R. Dunshea

Department of Animal Science: Faculty Publications

• Growing populations and reduced access to arable land mean that animal production systems will either need to intensify and/or produce more from a reducing land and other resource base.

• Variable and unpredictable environmental conditions mean that animal production faces numerous challenges. In add- ition to climate, these challenges include increased disease risk, increased nutritional deficiencies, and lack of capital to support diversification.

• Predicted changes in climate will impose selection pressures on traits important for biological fitness (and production).

• Genetic adaptation is important for the future of livestock systems. Animal adaptation involves trade-offs, which must be considered when selecting animals for …

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Livestock Animals To Study Infertility In Women, Mohamed A. Abedal-Majed, Andrea S. Cupp

Department of Animal Science: Faculty Publications

• Anovulation is a major cause of infertility in mammalian females.

• Ovarian research in humans is challenging due to the shortage of “normal tissue” that can be obtained from women that are trying to get pregnant.

• Livestock animals provide valuable resources to investigate the optimal intra-follicular environment required to facilitate folliculogenesis and translate to humans.

• Different livestock models may be more useful depending on the specific biological process studied.

Effect Of Environmental Temperature And Β-Adrenergic Agonist Supplementation On Rumen Volatile Fatty Acid Production In Sheep, Erin M. Duffy, Hannah C. Hamilton, Ty B. Schmidt, Dustin T. Yates, Jessica Lynn Petersen

Department of Animal Science: Faculty Publications

Many environmental and dietary factors affect ruminant livestock performance (Ames, 1980; Carberry et al., 2012). Energy used by ruminants is mainly derived from volatile fatty acids (VFA), including acetate, propionate, and butyrate, which are produced by bacterial fermentation of carbohydrates (Barcroft et al., 1944). With the importance of VFA production in ruminants (Bergman, 1990), it is essential to understand how various conditions livestock may be subjected to, such as ambient conditions and diet, can affect VFA production.

With the profound role of VFA production in energy status of the ruminant, and given that heat stress (HS) events can affect ruminal …

Changes In North American Mammal Niche Preferences From The Late Pleistocene To The Present, Silvia Pineda-Munoz, Anikó Tóth, S. Kathleen Lyons, Yue Wang, Jenny Mcguire

School of Biological Sciences: Presentations

Human population has exponentially grown since the last glaciation, especially across temperate areas with easy access to water sources, excluding mammal species from their former habitats. Thus, we anticipate a change in environmental niche preferences for temperature and precipitation as increased human population forces mammal species into more extreme climates within their environmental tolerances. For our study, we collected species occurrences from 20,000 ybp to the present for 59 North American mammal species. We inferred temperature and precipitation for each location using paleoclimate simulations (CCSM3). Overall, we found that mammals now live in areas that are warmer and dryer on …

Dendritic Cell-Derived Tslp Negatively Regulates Hif-1Α And Il-1Β During Dectin-1 Signaling, Matthew J. Elder, Steve J. Webster, Timothy J. Fitzmaurice, Aran S.D. Shaunak, Martin Steinmetz, Ronnie Chee, Ziad Mallat, E. Suzanne Cohen, David L. Williams, J. S. Hill Gaston, Jane C. Goodall

ETSU Faculty Works

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Thymic stromal lymphopoietin (TSLP) is a functionally pleotropic cytokine important in immune regulation, and TSLP dysregulation is associated with numerous diseases. TSLP is produced by many cell types, but has predominantly been characterized …

Nebraska Farm Real Estate Market Highlights 2018-2019, Jim Jansen, Jeffrey Stokes

Extension Farm and Ranch Management News

Introduction

The Nebraska Farm Real Estate Market Highlights 2018-2019 report represents the 41st edition to the annual series. These reports provide an important insight on agricultural land market dynamics for stakeholders across Nebraska. In today’s market, where market transactions exceeding a million dollars are the norm, objective market information and analysis is more critical than ever. The focus of the report continues to provide unbiased information on agricultural land values and rental rates so industry participants can make educated and informed decisions.

This year, the February 2019 survey of nearly 125 expert-panel members from across the state provided current information …

“Only The Beginning, Only Just The Start . . . Mostly I’M Silent”: New Constitutional Challenges With Data Collection Devices Brought Into The Home, Carol Nackenoff

Maryland Law Review

No abstract provided.

Six Horsemen Of Irresponsibility, Frank Pasquale

Maryland Law Review

No abstract provided.

Are First Generation Immigrants More Inclined To Participate In Clinical Research?, Aisha Farha

Master's Theses and Doctoral Dissertations

The number of immigrants entering the United States has increased dramatically in the past 30 years, but minorities and ethnic groups are underrepresented in research studies. This study examined first- and second-generation Arab American immigrants in Dearborn, Michigan, using a survey from 65 participants to determine the impact of generation on clinical research participation. Fifty-one (78%) of the respondents were first-generation immigrants, and 14 (22%) were second generation. There was no statistical difference between first- and second-generation immigrants in their willingness to participate in clinical research. Further research with a larger and more diverse population is needed to evaluate willingness …

Handling George Eliot’S Fiction, Peter J. Capuano

Department of English: Faculty Publications

An argument that George Eliot was a novelist intellectually, philosophically, and aesthetically ahead of the majority of her peers thankfully needs no defense two hundred years after her birth. This lofty status, however, does not mean that Eliot was impervious to the cultural preoccupations of her time. Quite the contrary. A central contention of this essay is that Eliot, despite her imposing intellectual reputation, engaged with her culture’s popular interest in human hands in ways that profoundly affected her fiction. As I have argued elsewhere,¹ the Victorians became highly cognizant of the physicality of their hands in large part …

Orda Weekly Update, 2019 08 26, Office Of Research Development And Administration

ORDA Weekly Update

No abstract provided.

Orda Weekly Update, 2019 08 19, Office Of Research Development And Administration

ORDA Weekly Update

No abstract provided.

Undergraduate Symposium, 2019, College Of Arts & Sciences

Undergraduate Symposium Programs

No abstract provided.

Size Estimation Of Pre‐Columbian Caribbean Fish, Sandrine Grouard, Sophia Perdikaris, Nídia Cristina Espíndola Rodrigues, Irvy R. Quitmyer

School of Global Integrative Studies: Faculty Publications

In this contribution, we present a methodological approach to the identification of pre‐Columbian Caribbean fisheries and examine the interrelationships of exploitation according to size for eight fish families, in a diachronic perspective for the Lesser Antilles. Based on the principles of size and growth allometries, biometric repositories have been reconstructed for modern families that represent different ecological environments: Holocentridae, Serranidae, Carangidae, Lutjanidae, Haemulidae, Scaridae, Acanthuridae, and Scombridae. The measured fish bone elements were selected based on their robustness and potential for recovery at archaeological sites. This resulted in a sample size totaling 563 modern osteological specimens, which provided reconstructed standard, …

Wpa News 110 (2019), World Pheasant Association

Galliformes Specialist Group and Affiliated Societies: Newsletters

WPA News (Winter 2019), number 110

Published by the World Pheasant Association

Reading The Aesopic Corpus: Slavery, Freedom, And Storytelling In The Life Of Aesop, Jeremy B. Lefkowitz

Classics Faculty Works

No abstract provided.

A Descriptive Study Of Some Trifolium L. (Clover) Taxa Grown In Bolu Province, Emel Uslu, Mehmet Teki̇n Babaç

Turkish Journal of Botany

Micromorphological characteristics of 13 Trifolium species, which are grown in the province of Bolu, were examined using a scanning electron microscope (SEM). The morphological characteristics determined from the study were subjected to morphometric analyses and their variation spectrums were defined. Tricolporate pollen grains showed two pollen shapes, prolate and subprolate, according to equatorial view. The smallest size of polar axis length (18.00 μm) was found in T. micranthum Viv. from section Chronosemium Ser.; the largest (88.95 μm) was found in T. hirtum All. from section Trifolium L.. Statistically, the smallest seeds were found in T. resupinatum L. from the section …

Dismantling The Master's House: Toward A Justice-Based Theory Of Community Economic Development, Etienne Toussaint

Journal Articles

Since the end of the American Civil War, scholars have debated the efficacy of various models of community economic development, or CED. Historically, this debate has tracked one of two approaches: place-based models of CED, seeking to stimulate community development through market-driven economic growth programs, and people-based models of CED, focused on the removal of structural barriers to social and economic mobility that prevent human flourishing. More recently, scholars and policymakers have turned to a third model from the impact investing community—the social impact bond, or SIB. The SIB model of CED ostensibly finds a middle ground by leveraging funding …

Reframing Radical Religion, Vanita Saleema Snow

Journal Articles

Like a thief in the night,1 politicians have stolen religion for their deceptive vices, using the term “radicalization” or “terrorism” to meet their needs.2 See Sahar F. Aziz, Caught in a Preventive Dragnet: Selective Counterterrorism in a Post-9/11 America, 47 GONZ. L. REV. 429, 481 (2012) (discussing how a police report equates “Muslim religiosity with radicalization toward terrorism”); David A. Bosworth, American Crusade: The Religious Roots of the War on Terror, 7 BARRY L. REV. 65, 65 (2006) (noting that American news and popular culture often portray religious people as “narrow-minded bigots out to destroy everything good and decent”); Ned …

Superintendents And The Micropolitics Of Innovation In Rural School Districts, Catherine Nunn Lawless

Theses and Dissertations--Education Sciences

Research shows that public school districts that follow traditional means of instruction and assessment are insufficiently preparing students for success in the today’s global world. As a result, students are entering into higher education institutions and the workforce without the necessary skills to succeed in these 21^st century environments. Extant literature suggest that there is a broad consensus on this perspective in public and private sectors nationally and globally. Evidence shows that some school district superintendents and their respective school boards continue to focus on improving the current practices and student academic performance and assessment. Other instructional leaders recognize …

Sacred Heart University Chapel: Celebrating 10 Years, 2009-2019, Office Of Mission And Catholic Identity

Mission & Culture Publications

The 10th Anniversary 2019 Edition. The Chapel of the Holy Spirit was dedicated on September 27, 2009.

“Members” Of Christ: Myth, Morals, And Masculinity In Puritan New England, Rebecca Farias

History Theses

No abstract provided.

Barriers To Implementing A Single-Use Plastic Bag Ban In Missoula, Tess Elizabeth Parker

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Single-use plastic bags have been in the media spotlight over the past several years due to their harmful environmental impact. Key issues include accumulating waste and litter pollution. The City of Missoula should enact a bag ban due to its environmentally conscious culture. Discussed in the paper are potential barriers and examples of successful bans and how to apply them locally.