Digital Commons Network^™

A Controlled Trial Of Mobile Short Message Service Among Participants In A Rural Cardiovascular Disease Prevention Program, Maria Odette Gore, Mori J. Krantz, Karen Albright, Brenda Beaty, Stephanie Coronel-Mockler, Sheana Bull, Raymond O. Estacio

Sociology and Criminology: Faculty Scholarship

The statewide Colorado Healthy Heart Solutions (CHHS) program provides cardiovascular disease (CVD) risk factor screening and education to the medically underserved and has been shown to improve CVD risk profiles. We aimed to enhance its effectiveness through addition of a mobile health (mHealth) intervention using SMS messaging (termed Cardio SMS). We conducted a prospective, non-randomized controlled pilot trial of this intervention implemented at 5 rural program sites (number of participants N = 204) compared with a contemporaneous propensity-score matched control group from 14 CHHS sites not receiving the intervention (N = 408) between 2012 and 2014. All participants were …

Pledges Of Faith: The Development Of Ancient Roman Business Law And Contemporary Applications, Devon Guanci

History & Classics Undergraduate Theses

It is no secret that the legacy of both the Roman Republic and Empire continue to influence Western culture and lifestyle today. In this thesis, I will specifically consider the development of Roman commercial and contract law. As Rome experienced continued expansion into the imperial age, commerce, use of contracts, and global trade worked to establish a robust economy in the empire. Thus, the established system of commercial law created a stable backbone that was necessary for the longevity of ancient Rome. While the modern United States is unlike Rome in many ways, many of the laws, as well as …

The Independent Reign Of Queen Victoria, Emilee Serwan

History & Classics Undergraduate Theses

Queen Victoria is one often most well know monarchs in both English and global history due to the extent of her empire, her personal achievements and for being the second longest reigning monarch in England. However, many have questioned if this reign was hers or if she was actually a figurehead, instead, controlled by the men in her life. In analyzing Victoria’s life and studying her diaries and letters, as well as, the writings of people surrounding her, it is evident that that her reign was ultimately led out of her own control and independently. Victoria did not see her …

Soldiers’ Motivations To Fight In World War Ii: The United States Army And The German Wehrmacht In The European Theatre, Anthony E. Hart

History & Classics Undergraduate Theses

The European theatre of the Second World War has often been perceived as an ideological conflict driven by nationalism and patriotism. Ideology, patriotism, and nationalism may have been the motivations of leaders and citizens on the home front in Germany and the United States, but what about the men in the American and German armies fighting on the front lines? They may have been similarly motivated prior to their deployment, but what motivated soldiers in the U.S. Army and the Wehrmacht to continue fighting as the war dragged on and as they endured the horrors of combat? Were the motivational …

Gardner-Webb Awards Over 200 Degrees During Commencement Exercises Dec. 15, Office Of University Communications

Gardner-Webb NewsCenter Archive

Gardner–Webb University hosted Fall Commencement on Saturday, Dec. 15, in the Lutz-Yelton Convocation Center. More than 200 graduates were honored during the ceremony. The ceremony featured graduates of Gardner-Webb’s traditional undergraduate program, as well as from GOAL — The Degree Completion Program (DCP), and graduate programs.

Serum Nutrient Levels And Aging Effects On Periodontitis, Jeffrey L Ebersole, Joshua Lambert, Heather Bush, Pinar Emecen Huja, Arpita Basu

Biostatistics Faculty Publications

Periodontal disease damages tissues as a result of dysregulated host responses against the chronic bacterial biofilm insult and approximately 50% of US adults > 30 years old exhibit periodontitis. The association of five blood nutrients and periodontitis were evaluated due to our previous findings regarding a potential protective effect for these nutrients in periodontal disease derived from the US population sampled as part of the National Health and Nutrition Examination Survey (1999–2004). Data from over 15,000 subjects was analyzed for blood levels of cis-β-carotene, β-cryptoxanthin, folate, vitamin D, and vitamin E, linked with analysis of the presence and severity of periodontitis. …

Watch & Learn - A Teacher's Guidebook For Film-Based Esl Course, Xiaoxue Zhu

Master's Projects and Capstones

Educators in the 21st century are continuously discovering more engaging teaching tools to facilitate language learners. In today's increasingly developing visual world, film stands out from other traditional materials for its unique features, such as the visuality and authenticity. With appropriately designed activities, film could be a valuable resource in teaching English as a second language (TESOL) setting, and also a perfect tool for inspiring cross-cultural communication and promoting critical thinking skills.

However, research has shown that ESL teachers feel reluctant to use film as a significant component in their classrooms even though they have recognized and affirmed the benefit …

A Force Sensor That Converts Fluorescence Signal Into Force Measurement Utilizing Short Looped Dna, Golam Mustafa, Cho-Ying Chuang, William A. Roy, Mohamed M. Farhath, Nilisha Pokhrel, Yue Ma, Kazuo Nagawawa, Edwin Antony, Matthew J. Comstock, Soumitra Basu, Hamza Balci

Biological Sciences Faculty Research and Publications

A force sensor concept is presented where fluorescence signal is converted into force information via single-molecule Förster resonance energy transfer (smFRET). The basic design of the sensor is a ~100 base pair (bp) long double stranded DNA (dsDNA) that is restricted to a looped conformation by a nucleic acid secondary structure (NAS) that bridges its ends. The looped dsDNA generates a tension across the NAS and unfolds it when the tension is high enough. The FRET efficiency between donor and acceptor (D&A) fluorophores placed across the NAS reports on its folding state. Three dsDNA constructs with different lengths were bridged …

2018-December-15-Veterans Day, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Elevated Temperature Progressive Damage And Failure Of Duplex Stainless Steel, Darren P. Luke

Civil Engineering ETDs

Ductile failure of metals has been the focus of research efforts within academia and industry for many years since it is tremendously important for understanding the failure of structures under extreme loading conditions. However, limited research has been dedicated to elevated temperature ductile failure, which is critical for evaluating catastrophic events such as industrial, structural or shipping vessel fires. A detailed investigation was conducted on the structural response of Duplex Stainless Steel at elevated temperatures. The temperature dependence of elastic modulus, yield strength, ultimate strength, and ductility was measured up to 1000°C and a continuum damage plasticity model was developed. …

Chemically Modified Monolayer Surfaces Influence Valvular Interstitial Cell Attachment And Differentiation For Heart Valve Tissue Engineering, Matthew N. Rush

Nanoscience and Microsystems ETDs

As a cell mediated-process, valvular heart disease (VHD) results in significant morbidity and mortality world-wide. In the US alone, valvular heart disease VHD is estimated to affect 2.5% of the population with a disproportionate impact on an increasing elderly populous. It is well understood that the primary driver for valvular calcification is the differentiation of valvular interstitial cells (VICs) into an osteoblastic-like phenotype. However, the factors leading to the onset of osteoblastic-like VICs (obVICs) and resulting calcification are not fully understood and a more complete characterization of VIC differentiation and phenotypic change is required before treatment of valve disease or …

Improve The Low Energy Sensitivity Of The Hawc Observatory, Zhixiang Ren

Optical Science and Engineering ETDs

The high altitude water cherenkov gamma-ray observatory (HAWC) has been fully operational since March of 2015 in Mexico at 4,100 meters above sea level on the hillside of the Sierra Negra Volcano. It consists of an array of 300 water cherenkov detectors, each equipped with four photo-multiplier tubes. HAWC operates 24-hours per day with a wide field-of-view (FOV, ∼ 2 sr) and a high duty cycle (∼ 95%). These make it a powerful survey and monitoring experiment for mapping the gamma ray sky at very high energies (VHE, 100 GeV to 100 TeV) and to study sources with varying intensities. …

Introduction: Reworking Walter Scott, Daniel Cook, Lucy Wood

Studies in Scottish Literature

An overview of Walter Scott's contemporary celebrity and evolving reputation, of scholarship on his afterlives, of the way his work has been reshaped in a variety of settings and media, and of the essays collected in this special issue.

Tangibility And Symbolism Along Historic Highway 66 In Albuquerque, Donatella Davanzo

American Studies ETDs

This dissertation is an interdisciplinary exploration of Highway 66 heritage in order to understand what makes the historic American route distinctive in the contemporary capitalist scenario. Although deterioration of the road is evident, it continues to epitomize an historic American infrastructure as well as a fascinating conceptualization of the United States in the American imagination and in the international consciousness. Historical evidence indicates that the formation of Highway 66 largely depended on a conjuncture of political, cultural, and socio-economic factors under capitalism and institutional forces and ideological principles of Manifest Destiny and American Exceptionalism. As an incarnation of these relationships …

Stability Of A Spinning Triangle Tethered Spacecraft System In A Circular Orbit, Matthew James Heitstuman

Mechanical Engineering ETDs

Equations of motion are derived for a spinning triangle tethered spacecraft system and are used to analyze the stability of such systems. Floquet theory is applied to the linearized, periodic coefficient, equations of motion to analyze spin stability as a function of triangle geometry and the average spin rate of the satellite relative to the angular velocity of the spacecraft orbiting around a central body. The results of the Floquet analysis show that spin stability is achievable for many combinations of spacecraft geometry and spin rate. Spacecraft engineers or operators for a triangle-shaped tethered spacecraft can use this information for …

An Analysis Of Mixed-Layer Clay Minerals And Major Element Geochemical Trends In Middle-Upper Pennsylvanian-Aged Paleosols As A Proxy For Characterizing Basin-Wide Diagenetic Patterns And The Paleoenvironment Of The Illinois Basin, U.S.A., Julia A. Mcintosh

Earth Sciences Theses and Dissertations

Pennsylvanian-aged paleosols from four Illinois Basin (IB) cores were sampled to characterize clay mineralogy, paleosol morphology, and major element geochemistry. This data combined with X-ray diffraction (XRD) and X-ray fluorescence (XRF) data from two other stratigraphically equivalent cores were used to better understand basin-wide diagenetic patterns. Paleosols unimpacted by diagenesis are considered reliable proxies for continued geochemical analyses and paleoclimate interpretations of middle to late Pennsylvanian (Desmoinesian-Missourian) low-latitude environments.

Reichweite Ordering, as determined from XRD analysis ofprofiles, indicates that diagenesis impacted the deep interior of the basin and the southern portion of the basin. Further investigation of illitization mechanisms derived …

Doing Business In America: A Jewish History, Purdue University Press

The Jewish Role in American Life: An Annual Review

American and Jewish historians have long shied away from the topic of Jews and business. Avoidance patterns grew in part from old, often negative stereotypes that linked Jews with money, and the perceived ease and regularity with which they found success with money, condemning Jews for their desires for wealth and their proclivities for turning a profit. A new, dauntless generation of historians, however, realizes that Jewish business has had and continues to have a profound impact on American culture and development, and patterns of immigrant Jewish exploration of business opportunities reflect internal, communal, Jewish-cultural structures and their relationship to …

Clinical Pharmacology Of Tisagenlecleucel In B-Cell Acute Lymphoblastic Leukemia., Karen Thudium Mueller, Edward Waldron, Stephan A. Grupp, John E. Levine, Theodore W. Laetsch, Michael A. Pulsipher, Michael W. Boyer, Keith August, Jason Hamilton, Rakesh Awasthi, Andrew M. Stein, Denise Sickert, Abhijit Chakraborty, Bruce L. Levine, Carl H. June, Lori Tomassian, Sweta S. Shah, Mimi Leung, Tetiana Taran, Patricia A. Wood, Shannon L. Maude

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Tisagenlecleucel is an anti-CD19 chimeric antigen receptor (CAR19) T-cell therapy approved for the treatment of children and young adults with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL).

PATIENTS AND METHODS: We evaluated the cellular kinetics of tisagenlecleucel, the effect of patient factors, humoral immunogenicity, and manufacturing attributes on its kinetics, and exposure-response analysis for efficacy, safety and pharmacodynamic endpoints in 79 patients across two studies in pediatric B-ALL (ELIANA and ENSIGN).

RESULTS: Using quantitative polymerase chain reaction to quantify levels of tisagenlecleucel transgene, responders (N = 62) had ≈2-fold higher tisagenlecleucel expansion in peripheral blood than nonresponders ( …

Tetra-Glucopyranosyl Diterpene Ent-Kaur-16-En-19-Oic Acid And Ent-13(S)-Hydroxyatisenoic Acid Derivatives From A Commercial Extract Of Stevia Rebaudiana (Bertoni) Bertoni, Wilmer Perera, Ion Ghiviriga, Douglas Rodenburg, Kamilla Alves, Frank Wiggers, Charles Hufford, Frank Fronczek, Mohamed Ibrahim, Ilias Muhammad, Bharathi Avula, Ikhlas Khan, James Mcchesney

Faculty and Student Publications (Open Access)

Stevia rebaudiana and its diterpene glycosides are one of the main focuses of food companies interested in developing novel zero calorie sugar substitutes since the recognition of steviol glycosides as Generally Recognized as Safe (GRAS) by the United States Food and Drug Administration. Rebaudioside A, one of the major steviol glycosides of the leaves is more than 200 times sweeter than sucrose. However, its lingering aftertaste makes it less attractive as a table-top sweetener, despite its human health benefits. Herein, we report the purification of two novel tetra-glucopyranosyl diterpene glycosides 1 and 3 (rebaudioside A isomers) from a commercial Stevia …

Looming Large: An Analysis And Evaluation On The Growth Of The Urban Informal Economy In Nigeria., Tamunotonye A. Sekibo Iii

Master's Theses

The Informal Economy looms large! The importance, magnitude and significance of the vast range of socio-economic activities taking place within and across diverse spaces of informality, particularly in nations situated in the Global South; can neither be overstated or underestimated. According to the International Labor Organization (ILO, 2018 p.v), approximately 60% of the world’s employed population - 2 billion people - obtain their source of income through their engagement in informal spaces.

The Future Of Innovation: How Libraries Support Entrepreneurs, Ilana Stonebraker, Heather A. Howard, Joe Collier, Saira Raza

Libraries Faculty and Staff Scholarship and Research

This paper highlights the ways that three different libraries are working to support entrepreneurs in their community: a public librarian connected with city government to support a small business development center; a librarian from a private university worked with social entrepreneurs that want to transform the world with business; a librarian from a large public land-grant works with entrepreneurs across the campus including business incubators and business competitions. The work these librarians do highlights the many ways libraries support entrepreneurs through collaboration, vision, and partnership.

Improving Infection Management Of The Institutionalized Elderly, Jovel Angela Viloria Broqueza

Doctor of Nursing Practice Projects

Abstract

As the elderly population rapidly grows in the United States, the burden of managing infection in long-term care facilities (LTCF) escalates. The use of evidence-based infection identification algorithms for early recognition and treatment of pneumonia, urinary tract infections (UTI) and skin and soft tissue infections (SSTI) was evaluated at a Midwest suburban 110-bed long-term care facility. Focus group sessions were conducted at the facility with four nurse practitioners, the medical director, eight nurses and certified nursing assistants (CNAs) prior to an educational in-service which was provided to all staff at the facility. As criteria of infection were reported, nurses …

Science In The News - Nicotinamide Exacerbates Motor Symptoms Of Parkinson's Disease In Mice., Layth A. Tabbaa

CHEM151

Melão, A. (2018, October 17). Nicotinamide Exacerbates Motor Symptoms of Parkinson's Disease in Mice. Retrieved November 7, 2017, from https://parkinsonsnewstoday.com/2018/10/10/nicotinamide-exacerbates-motor-symptoms-of-parkinsons-disease-in-mice/

Transitions Of Care: Implementing Early Follow-Up Appointment To Help Decrease Readmission Rate, Lualhati Espina Dursun

Master's Projects and Capstones

Abstract

Problem – The rate of readmission in the country is at a severe level. According to CMS, in 2017 the average national readmission rate was 18.4%(CMS, 2018). Hospitals are penalized for unnecessary readmissions (HRRP, 2018). In addition to the financial burden of readmissions, quality of life is decreased with readmission.

Context – Early or timely outpatient follow-up after hospitalization has been projected as a means of decreasing readmission rates.

Interventions – Integrating follow-up appointment to the current care transition - HUB process as a means in reducing readmission rates.

Measures & Results – Identified high-risk patients that need timely …

The Role Of Information Literacy In The Actualization Of Healthy Living: A Case Study Of Abia State, Juliana Obiageri Akidi Phd, Cln

Library Philosophy and Practice (e-journal)

The study examines the role of information literacy in the actualization of healthy living in Nigeria, with a special focus on Abia State. Information literacy is viewed as the ability to recognise the need for information, identify and locate appropriate sources of information, access the information, evaluate and use it effectively. Information literacy empowers people to have skills that will assist them to become independent lifelong learners, with better decision making abilities, especially in healthy living. Healthy living is defined as maintaining a state of complete physical, mental, and social well-being, which is not necessarily devoid of disease or infirmity. …

December 2018, Randy Curry, Cindy Brooks

RURAL ROCKS

Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy

Riding The Wave Of Microplastics In Bermuda, Molly E. Riihiluoma

Pell Scholars and Senior Theses

The presence of marine debris and microplastics in the Earth’s oceans are a global environmental issue. Bermuda’s location in the middle of the North Atlantic Gyre makes it the perfect case study for this work. As the crisis unfolds, Bermuda’s environment, economy, and population are at risk of witnessing firsthand the effects of plastic pollution. This paper relies on scholarly research as well as anecdotal evidence from retail stores and locals to compile information in order to provide necessary recommendations to benefit Bermuda’s ocean health. This research evaluates the pros and cons of policies which could mitigate the problem. Analysis …

Brand Loyalty In The Cruise Sector: Age Cohorts, Gender, And Travel Attributes As Key Moderators For Relationship Marketing Theory, Stephen Wen-Hung Wang, Maxwell Kuo-Hsuan Hsu, Angeline Close Scheinbaum, Feng-Ming Tsai

Journal of Marine Science and Technology–Taiwan

Testing established theory in relationship marketing, we examine the impact of customer relationship management on customer satisfaction and brand loyalty in the context of the cruise industry. Individual differences such as age cohort (e.g., millennials, Gen X, baby boomers), gender, and consumers’ desired travel attributes are examined as moderators. Cruise vacation consumers at an international cruise harbor were approached to complete an in-person survey (n = 226). Empirical findings support extant theory in relationship marketing in that consumers’ perception of relationship investment raises satisfaction and, in turn, brand loyalty. Notably, when customer relationship investment is degenerated into a second order …

A Simplified Two-Switching-Based Model-Free Predictive Current Controller For An Interior Permanent Magnet Synchronous Motor Drive System, Cheng-Kai Lin, Jen-Te Yu, Jyun-Ting Wang, Yen-Shin Lai, Hsing-Cheng Yu, Hao-Qun Huang

Journal of Marine Science and Technology–Taiwan

This paper presents a simplified two-switching-based modelfree predictive current control (STSB-MFPCC) method as well as its application to interior permanent magnet synchronous motor (IPMSM) drive systems. Unlike existing model predictive current controller (MPCC) that uses 7 basic voltage vectors, STSB-MFPCC employs 19 synthesized ones, with each of which consisting of two basic voltage vectors. The new method does not require any information about the load parameters, back electromotive force, nor the system model. Compared to modelbased controllers, the proposed one has a distinctive and appealing nature in that it is much less sensitive to system parameter variations. A digital signal …

Serum Nutrient Levels And Aging Effects On Periodontitis, Jeffrey L. Ebersole, Joshua Lambert, Heather Bush, Pinar Emecen Huja, Arpita Basu

Dental Medicine Faculty Research

Periodontal disease damages tissues as a result of dysregulated host responses against the chronic bacterial biofilm insult and approximately 50% of US adults >30 years old exhibit periodontitis. The association of five blood nutrients and periodontitis were evaluated due to our previous findings regarding a potential protective effect for these nutrients in periodontal disease derived from the US population sampled as part of the National Health and Nutrition Examination Survey (1999–2004). Data from over 15,000 subjects was analyzed for blood levels of cis-β-carotene, β-cryptoxanthin, folate, vitamin D, and vitamin E, linked with analysis of the presence and severity of periodontitis. …