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2018

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Lateral Circulation In A Partially Stratified Tidal Inlet, Linlin Cui, Haosheng Huang, Chunyan Li, Dubravko Justic Dec 2018

Lateral Circulation In A Partially Stratified Tidal Inlet, Linlin Cui, Haosheng Huang, Chunyan Li, Dubravko Justic

Faculty Publications

No abstract provided.

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But Are They Actually Healthier? Challenging The Health/Wellness Divide Through The Ethnography Of Embodied Ecological Heritage, Kristina Baines Dec 2018

But Are They Actually Healthier? Challenging The Health/Wellness Divide Through The Ethnography Of Embodied Ecological Heritage, Kristina Baines

Publications and Research

A holistic definition of ‘health’ remains difficult to operationalize, despite decades of attempts by medical anthropologists and the World Health Organization to do so. Anthropologists routinely reject dichotomous notions – belief vs. knowledge, wellness vs. health, mental vs. physical, environment vs. self – yet demands for physiological evidence of ‘health’ persist. In this article, I ask what evidence would sufficiently demonstrate health, and explore the possibility of measures that move beyond the physiological. Using ethnographic data collected in indigenous Maya communities in Belize and in immigrant communities in New York City, I argue that ecological heritage practices can provide a …

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Unh Researchers Find Lasting Impact Of Concussions On Young Adults, Robbin Ray Dec 2018

Unh Researchers Find Lasting Impact Of Concussions On Young Adults, Robbin Ray

Media Relations

No abstract provided.

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Ocean Deoxygenation And Zooplankton: Very Small Oxygen Differences Matter, Karen F. Wishner, Brad A. Seibel, Christopher Roman, C. Deutsch, Dawn Outram, C. T. Shaw, M. A. Birk, K. A. S. Mislan, T. J. Adams, D. Moore, S. Riley Dec 2018

Ocean Deoxygenation And Zooplankton: Very Small Oxygen Differences Matter, Karen F. Wishner, Brad A. Seibel, Christopher Roman, C. Deutsch, Dawn Outram, C. T. Shaw, M. A. Birk, K. A. S. Mislan, T. J. Adams, D. Moore, S. Riley

Graduate School of Oceanography Faculty Publications

Oxygen minimum zones (OMZs), large midwater regions of very low oxygen, are expected to expand as a result of climate change. While oxygen is known to be important in structuring midwater ecosystems, a precise and mechanistic understanding of the effects of oxygen on zooplankton is lacking. Zooplankton are important components of midwater food webs and biogeochemical cycles. Here, we show that, in the eastern tropical North Pacific OMZ, previously undescribed submesoscale oxygen variability has a direct effect on the distribution of many major zooplankton groups. Despite extraordinary hypoxia tolerance, many zooplankton live near their physiological limits and respond to slight …

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Unh Research Finds Recreationists Support Offshore Wind Energy Development, Robbin Ray Dec 2018

Unh Research Finds Recreationists Support Offshore Wind Energy Development, Robbin Ray

Media Relations

No abstract provided.

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The Catalytic Mechanism Of Electron-Bifurcating Electron Transfer Flavoproteins (Etfs) Involves An Intermediary Complex With Nad+, Gerrit J. Schut, Nishya Mohamed-Raseek, Monika Tokmina-Lukaszewska, David W. Mulder, Diep M. N. Nguyen, Gina L. Lipscomb, John Patrick Hoben, Angela Patterson, Carolyn E. Lubner, Paul W. King, John W. Peters, Brian Bothner, Anne-Frances Miller, Michael W. W. Adams Dec 2018

The Catalytic Mechanism Of Electron-Bifurcating Electron Transfer Flavoproteins (Etfs) Involves An Intermediary Complex With Nad+, Gerrit J. Schut, Nishya Mohamed-Raseek, Monika Tokmina-Lukaszewska, David W. Mulder, Diep M. N. Nguyen, Gina L. Lipscomb, John Patrick Hoben, Angela Patterson, Carolyn E. Lubner, Paul W. King, John W. Peters, Brian Bothner, Anne-Frances Miller, Michael W. W. Adams

Chemistry Faculty Publications

Electron bifurcation plays a key role in anaerobic energy metabolism, but it is a relatively new discovery, and only limited mechanistic information is available on the diverse enzymes that employ it. Herein, we focused on the bifurcating electron transfer flavoprotein (ETF) from the hyperthermophilic archaeon Pyrobaculum aerophilum. The EtfABCX enzyme complex couples NADH oxidation to the endergonic reduction of ferredoxin and exergonic reduction of menaquinone. We developed a model for the enzyme structure by using nondenaturing MS, cross-linking, and homology modeling in which EtfA, -B, and -C each contained FAD, whereas EtfX contained two [4Fe-4S] clusters. On the basis …

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Fundamental Limits On The Capacities Of Bipartite Quantum Interactions, Stefan Bäuml, Siddhartha Das, Mark M. Wilde Dec 2018

Fundamental Limits On The Capacities Of Bipartite Quantum Interactions, Stefan Bäuml, Siddhartha Das, Mark M. Wilde

Faculty Publications

Bipartite quantum interactions have applications in a number of different areas of quantum physics, reaching from fundamental areas such as quantum thermodynamics and the theory of quantum measurements to other applications such as quantum computers, quantum key distribution, and other information processing protocols. A particular aspect of the study of bipartite interactions is concerned with the entanglement that can be created from such interactions. In this Letter, we present our work on two basic building blocks of bipartite quantum protocols, namely, the generation of maximally entangled states and secret key via bipartite quantum interactions. In particular, we provide a nontrivial, …

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Front Matter And Table Of Contents Dec 2018

Front Matter And Table Of Contents

University of Miami Business Law Review

No abstract provided.

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Completion Of An Experiment, Michael J. Imperiale, Ira Blader, Patricia Bradford, Sarah E. F. D'Orazio, W. Paul Duprex, Craig D. Ellermeier, Ana Fernandez-Sesma, Katherine Mcmahon, Aaron Mitchell, Marcela F. Pasetti, Susannah Tringe Dec 2018

Completion Of An Experiment, Michael J. Imperiale, Ira Blader, Patricia Bradford, Sarah E. F. D'Orazio, W. Paul Duprex, Craig D. Ellermeier, Ana Fernandez-Sesma, Katherine Mcmahon, Aaron Mitchell, Marcela F. Pasetti, Susannah Tringe

Microbiology, Immunology, and Molecular Genetics Faculty Publications

No abstract provided.

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Damage Sensing And Mechanical Properties Of Laminate Composite Based Mwcnts Under Anticlastic Test, Mohammed Al-Bahrani, Muhsin Aljuboury, Alistair Cree Dec 2018

Damage Sensing And Mechanical Properties Of Laminate Composite Based Mwcnts Under Anticlastic Test, Mohammed Al-Bahrani, Muhsin Aljuboury, Alistair Cree

School of Engineering, Computing and Mathematics

No abstract provided.

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Comments On Judicial Independence And Impartiality In Isds: A Paper Prepared For The Uncitral Working Group Iii, Gus Van Harten, Pavla Křístková Dec 2018

Comments On Judicial Independence And Impartiality In Isds: A Paper Prepared For The Uncitral Working Group Iii, Gus Van Harten, Pavla Křístková

All Papers

This paper was prepared in support of the mandate of Working Group III to consider the possible reform of investor-state dispute settlement (ISDS) for reasons of independence and impartiality. It outlines the deep flaws in the current design of ISDS on this issue and offers ideas about reforms to incorporate essential safeguards

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The Relationship Between The Phosphate And Structural Carbonate Fractionation Of Fallow Deer Bioapatite In Tooth Enamel, Holly Miller, Carolyn Chenery, Angela L. Lamb, Hilary Sloane, Ruth F. Carden, Levent Atici, Naomi Sykes Dec 2018

The Relationship Between The Phosphate And Structural Carbonate Fractionation Of Fallow Deer Bioapatite In Tooth Enamel, Holly Miller, Carolyn Chenery, Angela L. Lamb, Hilary Sloane, Ruth F. Carden, Levent Atici, Naomi Sykes

Anthropology Faculty Research

Rationale The species‐specific relationship between phosphate (δ18OP values) and structural carbonate (δ18OC values) oxygen isotope ratios has been established for several modern and fossil animal species but until now it has not been investigated in European fallow deer (Dama dama dama). This study describes the relationship between phosphate and structural carbonate bioapatite in tooth enamel of extant fallow deer, which will help us further understand the species' unique environmental and cultural history. Methods The oxygen isotope composition of phosphate (δ18OP value) and structural carbonate (δ18OC value) of hydroxylapatite was determined in 51 modern fallow deer tooth enamel samples from across …

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Prevalence Of Infectious Organisms Observed In Cervical Smears Between 1997–2014 At Mubarak Al-Kabeer Hospital, Kuwait, Rana Al-Awadhi, Azza Al-Shaheen, Ahlam George, Sara S., Prem Sharma, Kusum Kapila Dec 2018

Prevalence Of Infectious Organisms Observed In Cervical Smears Between 1997–2014 At Mubarak Al-Kabeer Hospital, Kuwait, Rana Al-Awadhi, Azza Al-Shaheen, Ahlam George, Sara S., Prem Sharma, Kusum Kapila

Sultan Qaboos University Medical Journal

Objectives: This study aimed to examine gynaecological infectious agents observed in conventional and modified Papanicolaou cervical smears (CS) at a tertiary care hospital in Kuwait. Methods: This retrospective study analysed 121,443 satisfactory CS samples collected between 1997–2014 at the Mubarak Al-Kabeer Hospital, Kuwait. Conventional CS samples were obtained between 1997–2005, while modified CS were obtained between 2006–2014 following the introduction of ThinPrep® testing (Hologic Corp., Bedford, Massachusetts, USA). All samples were initially screened by cytoscreeners before being analysed by cytopathologists to determine the presence of specific infectious agents. Results: Overall, 8,836 (7.28%) of the cervical samples had infectious agents; of …

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Re: Perceptions Of Plagiarism Among Medical And Nursing Students In Erbil, Iraq, Sora Yasri, Viroj Wiwanitkit Dec 2018

Re: Perceptions Of Plagiarism Among Medical And Nursing Students In Erbil, Iraq, Sora Yasri, Viroj Wiwanitkit

Sultan Qaboos University Medical Journal

No abstract provided.

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A Probable Case Of Mucosal Fixed Drug Eruption Following Treatment With Silodosin, Eleni Klimi Dec 2018

A Probable Case Of Mucosal Fixed Drug Eruption Following Treatment With Silodosin, Eleni Klimi

Sultan Qaboos University Medical Journal

A fixed drug eruption consists of erythematous patches that appear on the skin and/or mucous membranes following administration of a drug which, once healed, leaves residual hyperpigmentation. We report a 76-year-old male who presented to the Thriasio General Hospital, Athens, Greece, in 2016 with erythema, oedema and blistering of the lower lip and glans penis following the administration of silodosin for benign prostatic hyperplasia. The eruption regressed two weeks after silodosin was discontinued.

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Evaluation Of Antibiotic Use Among Sepsis Patients In An Intensive Care Unit: A Cross-Sectional Study At A Referral Hospital In Indonesia, Ratna S. Dewi, Maksum Radji, Rizka Dec 2018

Evaluation Of Antibiotic Use Among Sepsis Patients In An Intensive Care Unit: A Cross-Sectional Study At A Referral Hospital In Indonesia, Ratna S. Dewi, Maksum Radji, Rizka

Sultan Qaboos University Medical Journal

Objectives: This study aimed to evaluate the appropriateness of antibiotic use and factors associated with outcomes among sepsis patients in an ntensive care unit (ICU). Methods: This cross-sectional study was carried out from February to May 2017 and included all adult patients with sepsis or septic shock admitted to the ICU of Dharmais Cancer Hospital, Jakarta, Indonesia. Data were collected from the patients’ medical records. Results: A total of 60 patients with sepsis or septic shock were admitted to the ICU during the study period. The most common source of infection was hospital-acquired pneumonia (61.7%) and the majority had two …

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Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A Case Report And Review Of The Literature, Rashid S. Al-Umairi, Fatma Al-Lawati, Fadhila M. Dec 2018

Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A Case Report And Review Of The Literature, Rashid S. Al-Umairi, Fatma Al-Lawati, Fadhila M.

Sultan Qaboos University Medical Journal

Amyloidosis is a disorder characterised by the extracellular deposition of amyloid, a fibrillary protein, in various organs such as the lungs. Pulmonary nodular amyloidosis can mimic other lung conditions that present with pulmonary nodules, such as metastasis, sarcoidosis and hyalinising granuloma. We report a 60-year-old man who presented to the Royal Hospital, Muscat, Oman, in 2017 with a history of shortness of breath upon exertion, orthopnoea and bilateral lower limb swelling. A chest X-ray showed bilateral nodular opacities. Enhanced chest computed tomography revealed bilateral pulmonary nodules with a predominantly perilymphatic and subpleural distribution, giving the impression of a neoplastic nodule. …

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A Triad Of Temporomandibular Joint Ankylosis, Mandibular Retrognathia And Severe Obstructive Sleep Apnoea: Case Report, Issa K. Al-Nuumani, Abdulaziz Bakathir, Ahmed Al-Abri, Mohammed, Hussein Al-Kindi, Intisar Al-Macki, Zainab Al-Balushi Dec 2018

A Triad Of Temporomandibular Joint Ankylosis, Mandibular Retrognathia And Severe Obstructive Sleep Apnoea: Case Report, Issa K. Al-Nuumani, Abdulaziz Bakathir, Ahmed Al-Abri, Mohammed, Hussein Al-Kindi, Intisar Al-Macki, Zainab Al-Balushi

Sultan Qaboos University Medical Journal

The surgical management of paediatric patients with temporomandibular joint (TMJ) ankylosis, mandibular retrognathia and obstructive sleep apnoea (OSA) is challenging. We report a nine-year-old boy who presented to the Department of Oral Health, Sultan Qaboos University Hospital, Muscat, Oman, in 2016 with complaints of limited mouth opening, loud snoring and excessive daytime sleepiness. He was diagnosed with TMJ ankylosis, mandibular retrognathia and severe OSA. The patient initially underwent mandibular distraction and, subsequently, release of the TMJ ankylosis and rib graft reconstruction. The overall patient outcome was successful, with improvement in OSA-related symptoms, good facial symmetry and adequate mouth opening.

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Two Different Causes Of Paediatric Hypercalcaemia, Stepan Kutilek, Ivana Plasilova, Viktor Dec 2018

Two Different Causes Of Paediatric Hypercalcaemia, Stepan Kutilek, Ivana Plasilova, Viktor

Sultan Qaboos University Medical Journal

Paediatric hypercalcaemia is a rare condition which can be easily overlooked or misdiagnosed. We report two paediatric patients who presented to the Department of Paediatrics, Pardubice Hospital, Pardubice, Czech Republic, in 2009 and 2010, respectively. Each patient was diagnosed with hypercalcaemia due to a different cause. The first case involved a seven-month-old infant who presented with failure to thrive, vomiting and psychomotor retardation. Fluorescent in situ hybridisation revealed Williams-Beuren syndrome. The second patient was a 16-year-old girl with abdominal pain and renal colic due to hypercalcaemia-induced urolithiasis. High parathyroid hormone serum levels suggested primary hyperparathyroidism. An adenoma of the left …

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Multifocal Skin Fluorodeoxyglucose Uptake In A Patient With A Large Abdominal Mass, Run Yu Dec 2018

Multifocal Skin Fluorodeoxyglucose Uptake In A Patient With A Large Abdominal Mass, Run Yu

Sultan Qaboos University Medical Journal

No abstract provided.

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2nd International Nursing Conference: Transforming Nursing Future - Technology, Innovation And Collaboration, Sultan Qaboos University Dec 2018

2nd International Nursing Conference: Transforming Nursing Future - Technology, Innovation And Collaboration, Sultan Qaboos University

Sultan Qaboos University Medical Journal

No abstract provided.

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Primary Plasma Cell Leukaemia: Case Report And Review Of The Literature, Sarika Singh, Ashutosh Rath, Surekha Dec 2018

Primary Plasma Cell Leukaemia: Case Report And Review Of The Literature, Sarika Singh, Ashutosh Rath, Surekha

Sultan Qaboos University Medical Journal

Plasma cell leukaemia (PCL) is one of the most aggressive and rarest forms of plasma cell dyscrasia. However, the diagnostic criteria for this condition have not yet been revised and there is no specific treatment to significantly improve the course of the disease. We report a 69-year-old male who presented to the Lok Nayak Hospital, New Delhi, India, in 2017 with dyspnoea and chest pain. A peripheral blood smear showed an absolute plasma cell count of 2.16 × 109/L. A bone marrow examination showed 61% atypical plasma cells exhibiting kappa light chain restriction. Biochemical investigations were consistent with a diagnosis …

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Noninvasive Ventilation And High-Flow Nasal Cannulae Therapy For Children With Acute Respiratory Failure: An Overview, Khaloud S. Al-Mukhaini, Najwa M. Al-Rahbi Dec 2018

Noninvasive Ventilation And High-Flow Nasal Cannulae Therapy For Children With Acute Respiratory Failure: An Overview, Khaloud S. Al-Mukhaini, Najwa M. Al-Rahbi

Sultan Qaboos University Medical Journal

Noninvasive ventilation (NIV) refers to the use of techniques to deliver artificial respiration to the lungs without the need for endotracheal intubation. As NIV has proven beneficial in comparison to invasive mechanical ventilation, it has become the optimal modality for initial respiratory support among children in respiratory distress. High-flow nasal cannulae (HFNC) therapy is a relatively new NIV modality and is used for similar indications. This review discusses the usefulness and applications of conventional NIV in comparison to HFNC.

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Teaching The Role Of Health Advocate: Reflections On Two Cross-Cultural Collaborative Advocacy Workshops For Medical Trainees And Instructors In Oman, Jessica Breton, Louis H. Francescutti, Yousef Dec 2018

Teaching The Role Of Health Advocate: Reflections On Two Cross-Cultural Collaborative Advocacy Workshops For Medical Trainees And Instructors In Oman, Jessica Breton, Louis H. Francescutti, Yousef

Sultan Qaboos University Medical Journal

In March 2014, medical educators from Canada and Oman collaborated to shape the foundation of health advocacy training in Oman. Using existing research and innovative tools, two workshops were developed, representing the first formalised approach to health advocacy for medical trainees in Oman. The development and application of the workshops highlighted many unique challenges and opportunities in advocacy training. This article summarises the process of developing and implementing the workshops as well as feedback from the participants and short-term consequences. Furthermore, this article seeks to explore the complexities of designing a cross-cultural curriculum. In particular, it reflects on how the …

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Correlation Of The Homeostasis Model Assessment Index And Adiponectin, Leptin And Insulin Levels To Body Mass Index-Associated Gene Polymorphisms In Adolescents, María D. Martínez-Martínez, Hugo Mendieta-Zerón, Luis Layton-Tovar, Cristian F., Rocío Torres-García, Laura E. Gutiérrez-Pliego, Eneida Camarillo-Romero, José D. Garduño-García, María D. Camarillo-Romero Dec 2018

Correlation Of The Homeostasis Model Assessment Index And Adiponectin, Leptin And Insulin Levels To Body Mass Index-Associated Gene Polymorphisms In Adolescents, María D. Martínez-Martínez, Hugo Mendieta-Zerón, Luis Layton-Tovar, Cristian F., Rocío Torres-García, Laura E. Gutiérrez-Pliego, Eneida Camarillo-Romero, José D. Garduño-García, María D. Camarillo-Romero

Sultan Qaboos University Medical Journal

Objectives: This study aimed to describe correlations between glucose, insulin and adipokine levels and the homeostasis model assessment (HOMA) index with regards to the presence/absence of fat mass and obesity-associated (FTO) rs9939609 and peroxisome proliferator-activated receptor (PPAR)-y rs1801282 single nucleotide polymorphisms (SNPs) as indicators of body mass index in adolescents. Methods: This cross-sectional study was conducted between September and December 2016 in Toluca, Mexico. A total of 71 students between 14–18 years old were included. Various anthropometric and laboratory measurements were collected, including lipid profile, glucose, insulin and adipokine levels and HOMA index. The degree of association between variables was …

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Prognostic Significance Of Blood Glucose Levels And Alterations Among Patients With Aluminium Phosphide Poisoning, Arvind Sharma, Prasanth Balasubramanian, Kiran D. Bhalla, Ashish Dec 2018

Prognostic Significance Of Blood Glucose Levels And Alterations Among Patients With Aluminium Phosphide Poisoning, Arvind Sharma, Prasanth Balasubramanian, Kiran D. Bhalla, Ashish

Sultan Qaboos University Medical Journal

Objectives: This study aimed to assess the prognostic significance of blood glucose levels and blood glucose alterations (i.e. hyper- or hypoglycaemia) among patients with aluminium phosphide (AlP) poisoning. Methods: This prospective observational study was conducted at the Postgraduate Institute of Medical Education & Research, Chandigarh, India, between January 2010 and June 2011. All patients presenting to the emergency department with a definitive history of AlP ingestion or symptoms compatible with AlP poisoning were included in the study. Blood glucose levels were recorded at presentation and every six hours thereafter. Alterations in blood glucose levels and other clinical and laboratory variables …

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High Efficacy Of Praziquantel In Schistosoma Haematobium-Infected Children In Taraba State, Northeast Nigeria: A Follow-Up Study, Robert S. Houmsou, Binga E. Wama, Hemen Uniga, John A., Elizabeth U. Amuta, Santaya L. Kela Dec 2018

High Efficacy Of Praziquantel In Schistosoma Haematobium-Infected Children In Taraba State, Northeast Nigeria: A Follow-Up Study, Robert S. Houmsou, Binga E. Wama, Hemen Uniga, John A., Elizabeth U. Amuta, Santaya L. Kela

Sultan Qaboos University Medical Journal

Objectives: This study aimed to assess the efficacy of praziquantel in reducing urinary schistosomiasis prevalence, parasite burden and morbidity rates among a previously reported sample of Schistosoma haematobium-infected children. In addition, predisposing factors for reinfection one year post-treatment were also determined. Methods: This prospective follow-up study was conducted between March 2014 and February 2015 among 675 previously reported children with urinary schistosomiasis in the Murbai and Surbai communities of Ardo Kola, Taraba State, Nigeria. A single dose of 40 mg/kg of praziquantel was administered to each infected child, with a second dose administered one month later if necessary. The number …

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Lactate Dehydrogenase And Β-Glucuronidase As Salivary Biochemical Markers Of Periodontitis Among Smokers And Non-Smokers, Syed A. Ali, Ravi L. Telgi, Amit Tantry, Irfan Q., Abdul Aleem Dec 2018

Lactate Dehydrogenase And Β-Glucuronidase As Salivary Biochemical Markers Of Periodontitis Among Smokers And Non-Smokers, Syed A. Ali, Ravi L. Telgi, Amit Tantry, Irfan Q., Abdul Aleem

Sultan Qaboos University Medical Journal

Objectives: This study aimed to establish lactate dehydrogenase (LDH) and β-glucuronidase as salivary biomarkers of periodontitis among smokers and non-smokers. Methods: This cross-sectional case-control study was conducted at the Aligarh Muslim University, Aligarh, India, between January and June 2017. A total of 200 participants were divided into four groups based on their periodontal and smoking statuses. Unstimulated mixed saliva samples were collected to estimate LDH and β-glucuronidase levels. In addition, total protein was estimated using Lowry’s method. Results: There was a significant increase in enzyme activity in the periodontitis groups compared to the non-periodontitis groups (P <0.001). However, significantly lower enzyme activity was observed among smokers, irrespective of periodontal status (P <0.001). Nevertheless, a receiver operating characteristic curve analysis indicated the diagnostic potential of both enzymes to be fair-to-excellent. Conclusion: Although smoking was found to significantly alter enzyme activity, LDH and β-glucuronidase were reliable salivary biomarkers of periodontitis among both smokers and non-smokers.

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An Open-Data-Driven Agent-Based Model To Simulate Infectious Disease Outbreaks, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher Dec 2018

An Open-Data-Driven Agent-Based Model To Simulate Infectious Disease Outbreaks, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

Agent-based models are a tool that can be used to better understand the dynamics of an infectious disease outbreak. An infectious disease outbreak is influenced by many factors including vaccination or immunity levels, population density, and the age structure of the population. We hypothesize that these factors along with interactions of factors and the actions of individuals would lead to outbreaks of different size and severity even in two towns that appear similar on paper. Thus, it is necessary to implement a model that is able to capture these interactions and the actions of individuals. Using openly available data we …

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Research Timeline For Exploring Methods Determining Mechanical Properties Of The Mouse Anterior Cruciate Ligament, Zachary Bram, Spencer Lake Dec 2018

Research Timeline For Exploring Methods Determining Mechanical Properties Of The Mouse Anterior Cruciate Ligament, Zachary Bram, Spencer Lake

Mechanical Engineering and Materials Science Independent Study

This paper describes an independent study performed in the Spencer Lake lab in Musculoskeletal Soft Tissue Mechanics from August-December of the 2018-2019 academic year. The project was determining mechanical properties of mice ACL with different genetic makeups. Knowing mechanical properties is a major step to repairing torn ligaments in humans bringing them back to full strength and functionality using tissue engineering. Continuing research from over the Summer, a finalized dissection method and protocol for isolating a mouse ACL and performing mechanical testing was created. Outlined by month, this paper describes progress made overcoming challenges from exploring methods to determine ACL …

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