Digital Commons Network^™

Does Rumination Mediate The Relationship Between Everyday Discrimination And Blood Pressure?, Sarah J. Roane

Electronic Theses and Dissertations

Social stressors, such as perceived discrimination, account for some health disparities by triggering a series of physiological responses (Selye, 1955) which may be prolonged by perseverative cognition such as rumination (Brosschot et al., 2005). In the current study, I investigated whether everyday discrimination is positively associated with both brooding or reflection rumination in Black/African American (AA) individuals, as well as whether brooding or reflection rumination mediate the potential associations between everyday discrimination and blood pressure. Data were collected from a community college sample and analyses were conducted using the whole sample (N = 286; 57.3% female; 51.6% White and 29.8% …

Differences In Flowering Sex Ratios Between Native And Invasive Populations Of The Seagrass Halophila Stipulacea, Hm Nguyen, P Kleitou, D Kletou, Y Sapir, G Winters

School of Biological and Marine Sciences

Deviations from the 1:1 sex ratio are common in dioecious plants. The tropical seagrass Halophila stipulacea is among an extremely rare group of dioecious plants which is widely recognized as female-biased. Here we report on differences in sex ratios between native (Eilat, northern Red Sea) and invasive (Cyprus, Mediterranean Sea) populations. While H. stipulacea populations were female-biased in the native region, invasive populations were either male- or female-biased. The existence of both sexes simultaneously in the Mediterranean invasive population, might help its ongoing expansion in the Mediterranean, thereby threatening local seagrasses species.

Molecular Adaptations For Sensing And Securing Prey And Insight Into Amniote Genome Diversity From The Garter Snake Genome, Perry W. Perry, Daren C. Card, Joel W. Mcglothlin, Giulia I.M. Pasquesi, Richard H. Adams, Drew R. Schield, Nicole R. Hales, Andrew B. Corbin, Jeffery P. Demuth, Federico G. Hoffmann, Michael W. Vandewege, Ryan K. Schott, Nihar Bhattacharyya, Belinda S.W. Chang, Nicholas R. Casewell, Gareth Whiteley, Jacobo Reyes-Velasco, Stephen P. Mackessy, Tony Gamble, Kenneth B. Storey, Kyle K. Biggar, Courtney N. Passow, Chih-Horng Kuo, Suzanne E. Mcgaugh, Anne M. Bronikowski, A.P. Jason De Konig, Scott V. Edwards, Michael E. Pfrender, Patrick Minx, Edmund D. Brodie Iii, Edmund D. Brodie Jr., Wesley C. Warren, Todd A. Castoe

Biological Sciences Faculty Research and Publications

Colubridae represents the most phenotypically diverse and speciose family of snakes, yet no well-assembled and annotated genome exists for this lineage. Here, we report and analyze the genome of the garter snake, Thamnophis sirtalis, a colubrid snake that is an important model species for research in evolutionary biology, physiology, genomics, behavior, and the evolution of toxin resistance. Using the garter snake genome, we show how snakes have evolved numerous adaptations for sensing and securing prey, and identify features of snake genome structure that provide insight into the evolution of amniote genomes. Analyses of the garter snake and other squamate …

Review Of The Book "Ego-Histories Of France And The Second World War: Writing Vichy," By Manuel Bragança And Fransiska Louwagie (Eds.), Shannon Lee Fogg

History and Political Science Faculty Research & Creative Works

No abstract provided.

Egfr Signaling From The Early Endosome., Julie A. Gosney

Electronic Theses and Dissertations

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is an integral component of proliferative signaling. When activated by a ligand at the plasma membrane, EGFR dimerizes with another ErbB family receptor, leading to kinase domain activation and transphosphorylation of C-terminus tyrosine residues. These phosphotyrosines act as crucial regulators of EGFR signaling as effector proteins dock to the receptor at these sites. The receptor undergoes clathrin-mediated endocytosis into early endosomes, where it can then be trafficked to a lysosome for degradation. However, the kinase domain of EGFR retains its activity during trafficking, suggesting that EGFR can continue …

A Novel Fibroblast Growth Factor 1 Variant Reverses Nonalcoholic Fatty Liver Disease In Type 2 Diabetes., Qian Lin

Electronic Theses and Dissertations

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder and is strongly associated with type 2 diabetes (T2D). Our recently engineered FGF1 partial agonist, carrying triple mutations (FGF1^△HBS) exhibits greatly reduced proliferative potential, while preserving the full metabolic activity of wild-type FGF1. This study tests the preventive and therapeutic effects of FGF1^△HBS on NAFLD in db/db T2D and explores potential mechanisms. The results showed that administration of FGF1^△HBS to 2-month-old db/db mice for 2 months constantly lowered blood glucose levels, improved insulin sensitivity, and lowered liver weight, lipid deposition, and …

Catching The Wave: Are Biology Graduate Students On Board With Evidence-Based Teaching?, Emma C. Goodwin, Jane N. Cao, Miles Fletcher, Justin L. Flaiban, Erin E. Shortlidge

Biology Faculty Publications and Presentations

Graduate students hold a critical role in responding to national calls for increased adoption of evidence-based teaching (EBT) in undergraduate classrooms, as they not only serve as teaching assistants, but also represent the pool from which future faculty will emerge. Through interviews with 32 biology graduate students from 25 institutions nationwide, we sought to understand the progress these graduate students are making in adopting EBT through qualitative exploration of their perceptions of and experiences with both EBT and instructional professional development. Initial inductive content analysis of interview transcripts guided the holistic placement of participants within stages of Rogers’s diffusions of …

Displacement Of The Transcription Factor B Reader Domain During Transcription Initiation, Stefan Dexl, Robert Reichelt, Katharina Kraatz, Sarah Schulz, Dina Grohmann, Michael S. Bartlett, Michael Thomm

Biology Faculty Publications and Presentations

Transcription initiation by archaeal RNA polymerase (RNAP) and eukaryotic RNAP II requires the general transcription factor (TF) B/ IIB. Structural analyses of eukaryotic transcription initiation complexes locate the B-reader domain of TFIIB in close proximity to the active site of RNAP II. Here, we present the first crosslinking mapping data that describe the dynamic transitions of an archaeal TFB to provide evidence for structural rearrangements within the transcription complex during transition from initiation to early elongation phase of transcription. Using a highly specific UV-inducible crosslinking system based on the unnatural amino acid para-benzoyl-phenylalanine allowed us to analyze contacts of …

Electrochemical Glucose Sensors Enhanced By Methyl Viologen And Vertically Aligned Carbon Nanotube Channels, Benjamin J. Brownlee, Meisam Bahari, John N. Harb, Jonathan C. Claussen, Brian D. Iverson

Faculty Publications

Freestanding, vertically aligned carbon nanotubes (VACNTs) were patterned into 16 μm diameter microchannel arrays for flow-through electrochemical glucose sensing. Non-enzymatic sensing of glucose was achieved by the chemical reaction of glucose with methyl viologen (MV) at an elevated temperature and pH (0.1 M NaOH), followed by the electrochemical reaction of reduced-MV with the VACNT surface. The MV sensor required no functionalization (including no metal) and was able to produce on average 3.4 electrons per glucose molecule. The current density of the MV sensor was linear with both flow rate and glucose concentration. Challenges with interference chemicals were mitigated by operating …

Electrochemical Glucose Sensors Enhanced By Methyl Viologen And Vertically Aligned Carbon Nanotube Channels, Benjamin J. Brownlee, Meisam Bahari, John H. Harb, Jonathan C. Claussen, Brian D. Iverson

Faculty Publications

Free-standing, vertically aligned carbon nanotubes (VACNTs) were patterned into 16 μm diameter microchannel arrays for flow-through electrochemical glucose sensing. Non-enzymatic sensing of glucose was achieved by the chemical reaction of glucose with methyl viologen (MV) at an elevated temperature and pH (0.1 M NaOH), followed by the electrochemical reaction of reduced-MV with the VACNT surface. The MV sensor required no functionalization (including no metal) and was able to produce on average 3.4 electrons per glucose molecule. The current density of the MV sensor was linear with both flow rate and glucose concentration. Challenges with interference chemicals were mitigated by operating …

Identifying Recreational Fisheries In The Mediterranean Through Social Media, I Giovos, I Keramidas, C Antoniou, A Deidun, Et Al

School of Biological and Marine Sciences

The impact of recreational fishing on fish stocks remains unknown, as this is inherently difficult to monitor, especially in areas such as the Mediterranean Sea where many species are targeted using a variety of fishing gears and techniques. The present study attempts to complement existing datasets andconstruct the profile of recreational fisheries in the EU-Mediterranean countries using videos publicly available on social media. A total of 1526 video records were selected, featuring the capture of 7799 fish specimens. The results show recreational fishing is multi-species in nature (26 species contributed to >80% % of the most numerically important species caught) …

Molecular Epidemiological Studies On Trypanosoma Evansi Type A And Type B In Camels (Camelus Dromedaries) From Five Different Regions Of Saudi Arabia Using The Its1 Rdna And Rotat 1.2 Vsg Gene, A Alanazi, R Puschendorf, M Alyousif, M Al-Khalifa, S Alharbi, Shehri Z Al, A Said, I Alanazi, H Al-Mohammed

School of Biological and Marine Sciences

Trypanosoma evansi is the most widespread of the pathogenic salivarian trypanosomes andcause a serious disease called (surra) that is affect the domestic animals such camels and horses in Tropical and subtropical countries and often leads to reduced productivity and economiclosses. Therefore, the objectives of the present study were to determine the prevalence rates oftrypanosomiasis using polymerase chain reaction (PCR) among camels from five different regions of Saudi Arabia and to sequence and characterized the T. evansi from these animals. Inthe current study, 832 camel blood samples collected from five different regions of Saudi Arabia for detecting T. evansi. A generic …

Effectiveness Of And User Experience With Web-Based Interventions In Increasing Physical Activity Levels In People With Multiple Sclerosis: A Systematic Review, Rachel Dennett, Hilary Gunn, Jennifer A. Freeman

School of Health Professions

No abstract provided.

Genetic Testing In Cardiovascular Medicine, Ali J Marian

The Texas Heart Institute Journal

No abstract provided.

Sex-Related Differences In Outcomes Of Thoracic Organ Transplantation And Mechanical Circulatory Support, Daoud Daoud, Faisal H Cheema, Jeffrey A Morgan, Gabriel Loor

The Texas Heart Institute Journal

No abstract provided.

Effect Of Skin-To-Skin Contact On Parents' Sleep Quality, Mood, Parent-Infant Interaction And Cortisol Concentrations In Neonatal Care Units: Study Protocol Of A Randomised Controlled Trial, Charlotte Angelhoff, Ylva Thernström Blomqvist, Charlotte Sahlén Helmer, Emma Olsson, Shefaly Shorey, Anneli Frostell, Evalotte Mörelius

Research outputs 2014 to 2021

INTRODUCTION: Separation after preterm birth is a major stressor for infants and parents. Skin-to-skin contact (SSC) is a method of care suitable to use in the neonatal intensive care unit (NICU) to minimise separation between parents and infants. Less separation leads to increased possibilities for parent-infant interaction, provided that the parents' sleep quality is satisfactory. We aimed to evaluate the effect of continuous SSC on sleep quality and mood in parents of preterm infants borndischarge.

METHODS AND ANALYSIS: A randomised intervention study with two arms-intervention versus standard care. Data will be collected from 50 families. Eligible families will be randomly …

Future Warming And Acidification Result In Multiple Ecological Impacts To A Temperate Coralline Alga, Megan J. Huggett, Kathryn Mcmahon, Rachele Bernasconi

Research outputs 2014 to 2021

Coralline algae are a crucial component of reef systems, stabilising reef substrate, providing habitat and contributing to accretion. Coralline algae and their surface microbial biofilms are also important as settlement cues for marine invertebrates, yet few studies address the impact of future environmental conditions on interactions between coralline algae, reef microbes and settlement by larvae of marine invertebrates. We exposed the temperate coralline algal species Amphiroa gracilis to warming and/or acidification scenarios for 21 days. Algae became bleached but photosystem II function was not measurably impacted. Settlement by larvae of the sea urchin Heliocidaris erythrogramma was reduced and the structure …

Complete Issue 10(2)

Speaker & Gavel

Complete digitized issue (volume 10, issue 2, January 1973) of Speaker & Gavel.

The Role Of Il-2rα-Dependent Signaling In Treg Development, Homeostasis, And Suppressive Function, Kevin Henry Toomer

Open Access Dissertations

Deletion of interleukin-2 (IL-2) or IL-2 receptor (IL-2R) subunits in mice causes lethal autoimmunity, establishing the vital contribution of IL-2R signaling to thymic development of Foxp3+ Tregs. However, precise mechanisms of IL-2-driven functional programming in Tregs and pathogenic autoreactive T cells remain undefined. To investigate these issues, we characterized a germline knockout (gKO) versus Treg-targeted conditional knockout (cKO) of the IL-2Rα chain (CD25) in mice. Both KO models developed lethal autoimmunity, but disease onset was delayed in CD25 gKO mice due to IL-2 deprivation among CD4+ and CD8+ T cells. Foxp3+ thymocytes from gKO mice showed greater reduction in Treg …

Deep Learning Based Imbalanced Data Classification And Information Retrieval For Multimedia Big Data, Yilin Yan

Open Access Dissertations

The development in information science has enabled an explosive growth of data, which attracts more and more researchers to engage in the field of big data analytics. Noticeably, in many real-world applications, large amounts of data are imbalanced data since the events of interests occur infrequently. Classification of imbalanced data is an important research problem as lots of real-world datasets have skewed class distributions in which the majority of instances (examples) belong to one class and far fewer instances belong to the others. A classifier induced from an imbalanced dataset is more likely to be biased towards the majority classes …

Investigation Of Spinal Cord Injury-Induced Gastrointestinal Dysfunction And Related Microbiota, Fungal, And Intestinal Alterations In A Rat Model And Humans With Spinal Cord Injury, Elisabeth Sarah Jeffrey

Open Access Theses

Spinal cord injury (SCI) is a serious medical condition that can result in a spectrum of neurological impairments and physical disabilities. There is an average of 11-12,000 new injuries per year in the US alone, and no cure for either the paralysis, or other secondary effects. Although there have been significant strides made in the research of the pathophysiology of Spinal Cord Injury (SCI), there is still limited knowledge on the consequences of SCI in remote organs. SCI produces significant effects on the entire body including the gastrointestinal tract. Individuals with SCI often experience severe, debilitating bowel dysfunction in addition …

Computational Analysis Of Genomic Variants Affecting Predicted Microrna:Target Interactions In Prostate Cancer., Angélica Paola Hernández Pérez

KGI Theses and Dissertations

Prostate cancer (PCa) is the most common cancer of men in the United States and is third only to lung and colon as a cause of cancer death. Clinical behavior of the disease is variable and the combination of prostate-specific antigen (PSA) screening and Gleason score staging are currently the best available molecular and pathology tools to predict outcomes. Cancer biology research establishes microRNAs (miRNAs) as key molecular components in both normal and pathological states. Thus, elucidating miRNAs perturbed by genomic alterations will expand our understanding of the molecular taxonomy of PCa with the aim to complement current practices in …

Emotion And The Seduction Of The Senses, Baroque To Neo-Baroque, Lisa Beaven, Angela Ndalianis

Studies in Medieval and Early Modern Culture

Emotion and the Seduction of the Senses, Baroque to Neo-Baroque examines the relationship between the cultural productions of the baroque in the seventeenth century and the neo-baroque in our contemporary world. It asks the question: "Is the baroque a recurring phenomenon that has returned in aspects of contemporary global culture, or is it something specific to the early modern period?" It argues one of the common and central features of both styles is their appeal to emotion. This volume illuminates how, rather than providing rationally ordered visual realms, both the baroque and the neo-baroque construct complex performative spaces whose spectacle …

Working On The Wayne | Running Buffalo Clover, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Working With Organic Peroxides In The Academic Lab, Patrick Dussault

Organic Peroxides: Safety Issues

ABSTRACT: The following is a brief introduction to peroxide safety from the viewpoint of a synthetic chemist. Major topics include: classes of organic peroxides; peroxide reactivity; hazard identification and minimization; reaction monitoring; and, hazards associated with auto-oxidation of peroxidizable solvents.

KEYWORDS: peroxide, hydroperoxide, hydroperoxyacetal, ozonide, perester, dihydroperoxide, monoperoxyacetal, active oxygen, peroxide strips, TLC indicator, self-accelerating decomposition, radical, exothermicity, transition metals.

CONTENTS: 1. Literature resources 2. Major classes of peroxides 3. Basis for peroxide reactivity 4. Determining reactivity and minimizing hazards a. Steps to take before an experiment b. Minimizing hazard during reactions c. Monitoring reactions d. Working with isolated peroxides …

Using Systematic Conservation Planning To Establish Management Priorities For Freshwater Salmon Conservation, Matanuska-Susitna Basin, Ak, Usa, Andrew W. Witt, Edd Hammill

Ecology Center Publications

1- The Alaskan Matanuska-Susitna Basin (MSB) provides habitat for all five Pacific salmon species, and their large seasonal spawning runs are important both ecologically and economically. However, the encroachment of human development through urbanization and extractive industries poses a serious risk to salmon habitat in the MSB.

2- Using systematic conservation planning techniques, different methods of incorporating anthropogenic risks were assessed to determine how to cost-effectively conserve salmon habitat in the area.

3- The consequences of four distinct conservation scenarios were quantified: no consideration of either urbanization or extractive industries (‘Risk ignored’ scenario); accounting for the risk of urbanization, and …

Catalyzing Capacity: Absorptive, Adaptive, And Generative Leadership, Elizabeth A. Castillo, Mai P. Trinh

Management Faculty Publications

Purpose

Organizations increasingly operate under volatile, uncertain, complex and ambiguous (VUCA) conditions. Traditional command-and-control leadership can be ineffective in such chaotic environments. The purpose of this paper is to outline an alternative model to help leaders and organizations navigate effectively through VUCA environments. By developing three fundamental capacities (absorptive, adaptive and generative), leaders can cultivate organizations capable of continuous synchronization with their fitness landscapes. Central tenets of the framework include diversity, slack, learning, humility, reflection in action and abductive logic.

Design/methodology/approach

This framework is designed based on literature insights, conceptual analysis and experts’ judgment. The paper integrates knowledge from a …

Reconfiguring Architectural Agency, Peter Olshavsky

Architecture Program: Faculty Scholarly and Creative Activity

This essay, for the exhibition "Steven Holl: Making Architecture,” argues that matter, things, and technologies are increasingly seen as co-constitutive of human agency. Studying this expanded conception of agency in the architecture of Holl reveals three opportunities. It enables us to re-describe the architect’s relation to architectural phenomenology beyond materiality. It reveals architecture’s active comportment in socially embedded settings, and it advances the idea that architecture makes us what we are.

Hydrodynamic Drivers Of Dissolved Oxygen Variability Within A Highly Developed Tidal Creek In Myrtle Beach, South Carolina, Douglas Matthew Pastore

Electronic Theses and Dissertations

Erosion and water quality degradation have been observed in Singleton Swash in Myrtle Beach, SC, and have been hypothesized to be related to migration of the beach-face channel. Dredging this channel temporarily fixes erosional threats to nearby infrastructure but the effects on water quality are not well understood. It is hypothesized that variations in dissolved oxygen (DO) concentration (used here as a proxy for water quality) within the water column are related to changes in vertical mixing and transport due to oceanic tidal forcing. This study utilizes current meters, pressure sensors, and optical DO probes to measure and study the …

Unique Osmoregulatory Morphology In Primitive Sharks: An Intermediate State Between Holocephalan And Derived Shark Secretory Morphology, Matthew Eric Larsen

Electronic Theses and Dissertations

Discovery of an unusual rectal gland in the Atlantic sixgill shark, Hexanchus vitulus, led to examination of rectal glands in 29 species of epipelagic and deep-sea sharks. Eight of 14 deep-sea species of sharks had digitiform glands that were previously assumed to be characteristic of elasmobranchs (N=281; mean width-length ratio ± SD = 0.18 ± 0.07). Hematoxylin-and-eosin stained sections from deep-sea sharks were similar to those from shallow water sharks. Glands from the family Somniosidae were kidney bean-shaped (N = 3; mean width-length ratio ± SD = 0.46 ± 0.05); whereas those from the families Echinorhinidae and Hexanchidae appeared lobulate …