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Hydrologic History Regulates Microbial Biofilm Diversity And Ecosystem Function, Allison R. Rober, Leah C. Reese, Shawn P. Brown, Katherine D. Mcmahon, Stilianos Louca, Jillian Cieslik, Evan Kane, Merritt R. Turetsky, Kevin H. Wyatt Apr 2026

Hydrologic History Regulates Microbial Biofilm Diversity And Ecosystem Function, Allison R. Rober, Leah C. Reese, Shawn P. Brown, Katherine D. Mcmahon, Stilianos Louca, Jillian Cieslik, Evan Kane, Merritt R. Turetsky, Kevin H. Wyatt

Michigan Tech Publications

Aquatic biofilms are an understudied component of northern peatlands and are expected to play a more prominent role in ecosystem processes in areas where aquatic habitat is expanding. The goal of this study was to investigate how hydrologic history influences biofilm diversity and functional genes. This study was conducted in a long-term water table manipulation that simulates drought (lowered water table treatment) and flooding (raised water table treatment) conditions relative to a control treatment (no manipulation). We used a combination of metabarcoding and metagenomic approaches to (1) examine the diversity of eukaryotic algae, cyanobacteria, bacteria and fungi within the biofilm …


Trajectories Of Plasma And Csf Mtbr-Tau243 And Phosphorylated-Tau Species Across The Alzheimer's Disease Continuum, Lyduine E Collij, Gemma Salvadó, Kanta Horie, Nicolas R Barthélemy, Tobey J Betthauser, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Suzanne E Schindler, Rik Ossenkoppele, Shorena Janelidze, Niklas Mattsson-Carlgren, Randall J Bateman, Oskar Hansson Apr 2026

Trajectories Of Plasma And Csf Mtbr-Tau243 And Phosphorylated-Tau Species Across The Alzheimer's Disease Continuum, Lyduine E Collij, Gemma Salvadó, Kanta Horie, Nicolas R Barthélemy, Tobey J Betthauser, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Suzanne E Schindler, Rik Ossenkoppele, Shorena Janelidze, Niklas Mattsson-Carlgren, Randall J Bateman, Oskar Hansson

2020-Current year OA Pubs

To efficiently implement plasma and cerebrospinal fluid (CSF) biomarkers for staging and prognosis of Alzheimer disease (AD), we must understand their dynamics across disease progression. We analyzed participants from the Swedish BioFINDER-2 study with mass spectrometry measurements of plasma and CSF tau species, including eMTBR-tau243/MTBR-tau243 and phosphorylation occupancies (%p-tau). Disease duration was estimated using Aβ-PET and tau-PET with the SILA algorithm. Bootstrapped LOESS models showed that %p-tau217 changes earliest, increasing just before Aβ-PET positivity. Other p-tau species changed later, with smaller dynamic ranges and earlier ceiling effects. %p-tau205 and MTBR-tau243 changes aligned with tau-PET positivity onset, while MTBR-tau243-especially plasma eMTBR-tau243-tracked …


Evapecognition: An 18-Year Dataset Of Great Ape Cognition, Alejandro Sánchez-Amaro, Sonja J. Ebel Van Wijk, Carin Molenaar, Akzira Abuova, Lizbeth Mujica-Manrique, Sarah M. Leisterer-Peoples, Bret Beheim, Luke Maurits, Anna Albiach-Serrano, Matthias Allritz, Nazli Altınok, Federica Amici, Alice M.I. Auersperg, Filippo Aureli, Elisa Bandini, Jochen Barth, Leïla Benziad, Bettina E. Bläsing, Manuel Bohn, Marie Bourjade, Juliane Bräuer, Marie Hélène Broihanne, Sarah F. Brosnan, Nereida Bueno-Guerra, Thomas Bugnyar, David Buttelmann, Frances Buttelmann, Trix Cacchione, Malinda Carpenter, Fernando Colmenares Apr 2026

Evapecognition: An 18-Year Dataset Of Great Ape Cognition, Alejandro Sánchez-Amaro, Sonja J. Ebel Van Wijk, Carin Molenaar, Akzira Abuova, Lizbeth Mujica-Manrique, Sarah M. Leisterer-Peoples, Bret Beheim, Luke Maurits, Anna Albiach-Serrano, Matthias Allritz, Nazli Altınok, Federica Amici, Alice M.I. Auersperg, Filippo Aureli, Elisa Bandini, Jochen Barth, Leïla Benziad, Bettina E. Bläsing, Manuel Bohn, Marie Bourjade, Juliane Bräuer, Marie Hélène Broihanne, Sarah F. Brosnan, Nereida Bueno-Guerra, Thomas Bugnyar, David Buttelmann, Frances Buttelmann, Trix Cacchione, Malinda Carpenter, Fernando Colmenares

School of Psychology

The study of great ape cognition offers insights into the evolutionary origins of human intelligence, but is hindered by small sample sizes and restricted access to data. To address this, we present the EVApeCognition Dataset, a publicly available resource comprising 262 experimental datasets from 150 scientific publications from the Wolfgang Köhler Primate Research Center (2004–2021) in Leipzig, Germany. Eighty-one apes participated in 150 studies, with a majority (N = 78) participating in more than one study. Publication of the dataset aims to make these unique datasets accessible for future meta-analyses and correlational analyses, helping us better understand how our great …


The Effectiveness Of Classical Guidance Service Program In Developing Empathy In Students, Siti Cahyati, Ananda Rachmaniar, Syariih Fitrah Rayaginansih Apr 2026

The Effectiveness Of Classical Guidance Service Program In Developing Empathy In Students, Siti Cahyati, Ananda Rachmaniar, Syariih Fitrah Rayaginansih

Jurnal Pendidikan Humaniora

Empathy is a crucial aspect in social professions such as counseling and psychotherapy, acting as a bridge in building an effective therapeutic relationship between counselors and clients. This study aims to test the effectiveness of classical guidance services in developing empathy in students of the Guidance and Counseling study program, Ma'soem University, class of 2023. The study used a quantitative method with a one-group pre-test post-test pre-experimental design, involving 42 students with a saturated sample technique. The instrument used was the Empathy Scale for Prospective Counselor (ESPC) based on Segal's theory (2018). The results of the analysis showed a significance …


Systematic Design And Optimization Of Porous Bone Plates Using Taguchi Method And Finite Element Analysis, Aliaa A. Farraj, Tawakol A. Enab, Hanan M. Amer, Mostafa A. Elbahloul Apr 2026

Systematic Design And Optimization Of Porous Bone Plates Using Taguchi Method And Finite Element Analysis, Aliaa A. Farraj, Tawakol A. Enab, Hanan M. Amer, Mostafa A. Elbahloul

Mansoura Engineering Journal

Solid bone fixation plates, although clinically effective, often induce stress shielding and impair periosteal blood flow due to their mismatch in stiffness with cortical bone. To overcome these limitations, this study proposes lattice-engineered porous bone plates designed to balance mechanical integrity and biological compatibility. A systematic parametric investigation was conducted by varying three design variables: crystal structure type (diamond, fluorite, and gyroid), porosity levels (50%, 70%, and 90%), and structure layout. Three-dimensional models were developed using nTopology, and finite element analysis (FEA) was performed under a static compressive load to evaluate stress distribution. A Taguchi L9 orthogonal array was employed …


Transformation Of Environmental Education (Plh) Learning With Contextual-Based E-Modules At Pabentengang Tpa, Najlah Shalsa Byla, Didik Taryana, Yusuf Suharto Apr 2026

Transformation Of Environmental Education (Plh) Learning With Contextual-Based E-Modules At Pabentengang Tpa, Najlah Shalsa Byla, Didik Taryana, Yusuf Suharto

Jurnal Pendidikan Humaniora

The development of this e-module is motivated by the limitations of PLH teaching materials which are only conceptual and do not link theory to real phenomena around students, for example the problem of waste management at the Pabentengang TPA. These limitations cause learning to be less interesting and meaningful. Therefore, this study aims to transform PLH learning through the development of contextual-based e-modules that link theory to local environmental problems directly. This study uses the ADDIE development model, which includes the stages of analysis, design, development, implementation, and evaluation. The validity of the product was assessed by material experts and …


Approach To Physics Education Using Local Ai With Rag For Open Educational Materials Generation, Dmitriy Beznosko Apr 2026

Approach To Physics Education Using Local Ai With Rag For Open Educational Materials Generation, Dmitriy Beznosko

All Things Open

The new tool that starts to enter all parts of our life is AI – and it enters education as well. There are two standing large concerns with using AI for education – the safety of students’ data and the AI missing specific knowledge about the given class. The approach of using the Retrieval Augmented Generation (RAG) provides the user data to the locally run LLM model (using Ollama framework, a free and open-source tool that allows you to run large language models locally on your system) as a context for the generation of the OER materials. As this AI …


Harnessing The Gut-Diet Axis To Enhance Chemotherapy And Immunotherapy, Jill Carline Apr 2026

Harnessing The Gut-Diet Axis To Enhance Chemotherapy And Immunotherapy, Jill Carline

Bryant REDay (Research and Engagement Day)

The human microbiome, a complex ecosystem of trillions of microorganisms including bacteria, fungi, and viruses, represents a critical "gut-diet axis" that significantly influences cancer progression and therapeutic efficacy. While a state of homeostasis supports systemic immunity, dysbiosis is linked to chronic inflammation and can actively promote resistance to standard cytotoxic chemotherapies and modern immune checkpoint inhibitors. Specifically, research indicates that Bacteroides fragilis (ETBF) promotes resistance to 5-Fluorouracil and Oxaliplatin in colorectal cancer by activating Notch1 receptors to inhibit apoptosis and push cancer cells into a resilient, stem-cell-like state. Conversely, the introduction of fiber-rich and fermented foods can cultivate beneficial bacteria …


The Shorthorn: June 30, 1982 Apr 2026

The Shorthorn: June 30, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: June 16, 1982 Apr 2026

The Shorthorn: June 16, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: June 23, 1982 Apr 2026

The Shorthorn: June 23, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: June 9, 1982 Apr 2026

The Shorthorn: June 9, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: May 4, 1982 Apr 2026

The Shorthorn: May 4, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: April 15, 1982 Apr 2026

The Shorthorn: April 15, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: March 26, 1982 Apr 2026

The Shorthorn: March 26, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: March 24, 1982 Apr 2026

The Shorthorn: March 24, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: March 10, 1982 Apr 2026

The Shorthorn: March 10, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: March 2, 1982 Apr 2026

The Shorthorn: March 2, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 26, 1982 Apr 2026

The Shorthorn: February 26, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 18, 1982 Apr 2026

The Shorthorn: February 18, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 12, 1982 Apr 2026

The Shorthorn: February 12, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 9, 1982 Apr 2026

The Shorthorn: February 9, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 10, 1982 Apr 2026

The Shorthorn: February 10, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: February 5, 1982 Apr 2026

The Shorthorn: February 5, 1982

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: December 9, 1981 Apr 2026

The Shorthorn: December 9, 1981

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: November 19, 1981 Apr 2026

The Shorthorn: November 19, 1981

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: November 17, 1981b Apr 2026

The Shorthorn: November 17, 1981b

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: November 17, 1981 Apr 2026

The Shorthorn: November 17, 1981

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: November 12, 1981 Apr 2026

The Shorthorn: November 12, 1981

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: November 13, 1981 Apr 2026

The Shorthorn: November 13, 1981

The Shorthorn Newspaper Collection: 1980s

No abstract provided.