Digital Commons Network^™

Meta-Analytic Summary Of Parasites And Diseases Of Elasmobranchs Found In Florida Waters, Alexis S. Modzelesky

HCNSO Student Capstones

Elasmobranchs have conservational and commercial importance. There is a need for a more complete understanding of their health, due to their ability to shape trophic webs and their money-making potential with fishers and ecotourists. Sharks have been known to influence the strength of food webs, including reef ecosystems where many fish species are harvested for food. The investigation of pathogenic agents and diseases in elasmobranchs has been biased to favor those natural enemies that inhabit the digestive system and epidermal surfaces. Certain groups of parasites such as cestodes, copepods, and monogeneans, were most often recorded in this study. The bacterial …

Physiological Responses Of The State – Listed Texas Pigtoe To Environmental Stress, Sara M. Rumbelow

Biology Theses

Systematic habitat destruction over the last 100 years combined with major anthropogenic stressors such as aquatic contaminants, exotic species, and economic endeavors are driving the decline in freshwater unionid species diversity. Two hundred fifty-seven individual adult Texas pigtoe (Fusconaia askewi) mussels (mean length, mm ± 1 SD; 58.7 ± 13.8) were collected from the upper Sabine river near Hawkins, Texas and taken to the University of Texas at Tyler to evaluate three factors likely impacting mussels in East Texas: siltation (a surrogate for bank erosion), elevated temperature and nitrogen. The impact of siltation was evaluated by burying mussels …

Positioning Ethos In/For The Twenty-First Century: An Introduction To Histories Of Ethos, James S. Baumlin, Craig A. Meyer

College of Arts and Letters

The aim of this essay is to introduce, contextualize, and provide rationale for texts published in the Humanities special issue, Histories of Ethos: World Perspectives on Rhetoric. It surveys theories of ethos and selfhood that have evolved since the mid-twentieth century, in order to identify trends in discourse of the new millennium. It outlines the dominant theories—existentialist, neo-Aristotelian, social-constructionist, and poststructuralist—while summarizing major theorists of language and culture (Archer, Bourdieu, Foucault, Geertz, Giddens, Gusdorf, Heidegger). It argues for a perspectivist/dialectical approach, given that no one theory comprehends the rich diversity of living discourse. While outlining the “current state of theory,” …

Thermal Vibration Contribution To Continuum Stress In The Elastic Regime, Ranganathan Parthasarathy

Civil and Architectural Engineering Faculty Research

Homogeneous deformation of an ordered crystalline solid at finite temperature can cause non-affine transformation of atomic trajectories. In such a case, continuum measures based on affine transformation of trajectories are insufficient to ensure energetic equivalence between the atomic and continuum scales. We use molecular dynamics simulation of fcc aluminum in NVT ensembles to demonstrate that the second moments of atomic positions about equilibrium show increasing deviation from affine behavior with strain and temperature. While the Cauchy-Born rule enforces affine deformation of the crystal in the static sense, second moments have been used to quantify non-affinity in thermal vibrations due to …

Topical Administration Of Egf Suppresses Immune Response And Protects Skin Barrier In Dncb-Induced Atopic Dermatitis In Nc/Nga Mice, Young Je Kim, Mi Ji Choi, Dong Ho Bak, Byung Chul Lee, Eun Jung Ko, Ga Ram Ahn, Seung Won Ahn, Moo Joong Kim, Jungtae Na, Beom Joon Kim

Biological Sciences Faculty Publications

Atopic dermatitis (AD) is a common inflammatory skin disease characterized by a complex, heterogeneous pathogenesis including skin barrier dysfunction, immunology, and pruritus. Although epidermal growth factor (EGF) is essential for epithelial homeostasis and wound healing, the effect of EGF on AD remains to be explored. To develop a new therapy for AD, the anti-AD potential of EGF was investigated by inducing AD-like skin lesions in NC/Nga mice using 2,4-dinitrochlorobenzene (DNCB). EGF was administrated to NC/Nga mice to evaluate its therapeutic effect on DNCB-induced AD. EGF treatment improved dermatitis score, ear thickness, epidermal hyperplasia, serum total immunoglobulin E level, and transepidermal …

Usu Engineering Student Awarded Prestigious Academic Fellowship, Usu College Of Engineering

College of Engineering News

USU’s Darcie Christensen is one of 31 engineering students nationwide — and the only person in Utah — to receive a 2018–19 Tau Beta Pi Honor Society academic fellowship.

Dancing Dentist Back For In-My-Feelings Challenge With Ymca Campers, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Above The Bar, Jennifer Saunders

UNH Today Archive

No abstract provided.

Aged Murine Hematopoietic Stem Cells Drive Aging-Associate Immune Remodeling, Hanna Leins, Medhanie Mulaw, Karina Eiwen, Vadim Sakk, Ying Liang, Michael Denkinger, Hartmut Geiger, Reinhold Schirmbeck

Toxicology and Cancer Biology Faculty Publications

Aging-associated remodeling of the immune system impairs its functional integrity and contributes to increased morbidity and mortality in the elderly. Aging of hematopoietic stem cells (HSCs), from which all cells of the adaptive immune system ultimately originate, might play a crucial role in the remodeling of the aged immune system. We recently reported that aging of HSCs is, in part, driven by elevated activity of the small RhoGTPase Cdc42 and that aged HSCs can be rejuvenated in vitro by inhibition of the elevated Cdc42 activity in aged HSCs with the pharmacological compound CASIN. To study the quality of immune systems …

Writing A Moral Code: Algorithms For Ethical Reasoning By Humans And Machines, James F. Mcgrath, Ankur Gupta

Scholarship and Professional Work - LAS

The moral and ethical challenges of living in community pertain not only to the intersection of human beings one with another, but also our interactions with our machine creations. This article explores the philosophical and theological framework for reasoning and decision-making through the lens of science fiction, religion, and artificial intelligence (both real and imagined). In comparing the programming of autonomous machines with human ethical deliberation, we discover that both depend on a concrete ordering of priorities derived from a clearly defined value system.

Immobilization Nematodes For Live Imaging Using An Agarose Pad Produced With A Vinyl Record, Katherine A. Rivera Gomez, Mara Schvarzstein

Publications and Research

Numerous microfluidic systems have been developed and used for live imaging of Caenorhabditis nematodes (Allen et al., 2008; Zhang et al., 2008; Krajniak and Lu, 2010; Krajniak et al., 2013; Cornaglia et al., 2015). These systems can be costly, complex to set up, or require high-maintenance between uses. In addition, microfluidic rigs can be thick, preventing live imaging of worms from strains expressing low fluorescence fusion proteins. In the absence of elaborate microfluidic rigs, most live imaging protocols utilize flat agarose pads along with anesthetics and/or microbeads to immobilize the nematodes (Kim et al., 2013). Since this method does not …

Why Large Seeds With Physical Dormancy Become Nondormant Earlier Than Small Ones, Ailton G. Rodrigues-Junior, Ana Caroline M. P. Mello, Carol C. Baskin, Jerry M. Baskin, Denise M. T. Oliveira, Queila S. Garcia

Biology Faculty Publications

Under natural conditions, large seeds with physical dormancy (PY) may become water permeable earlier than small ones. However, the mechanism for this difference has not been elucidated. Thus, our aim was to evaluate the traits associated with PY in seeds of Senna multijuga (Fabaceae) and to propose a mechanism for earlier dormancy-break in large than in small seeds. Two seedlots were collected and each separated into large and small seeds. Seed dry mass, water content, thickness of palisade layer in the hilar and distal regions and the ratio between palisade layer thickness (P) in the lens fissure and seed mass …

Structure Based Modulation Of Electron Dynamics In Meso-(4-Pyridyl)-Bodipys: A Computational And Synthetic Approach, Daniel J. Lamaster, Nichole E.M. Kaufman, Adam S. Bruner, M. Graça H. Vicente

Faculty Publications

© 2018 American Chemical Society. The effects of structural modification on the electronic structure and electron dynamics of cationic meso-(4-pyridyl)-BODIPYs were investigated. A library of 2,6-difunctionalized meso-(4-pyridyl)-BODIPYs bearing various electron-withdrawing substituents was designed, and DFT calculations were used to model the redox properties, while TDDFT was used to determine the effects of functionalization on the excited states. Structural modification was able to restructure the low-lying molecular orbitals to effectively inhibit d-PeT. A new meso-(4-pyridyl)-BODIPY bearing 2,6-dichloro groups was synthesized and shown to exhibit enhanced charge recombination fluorescence. The fluorescence enhancement was determined to be the result of functionalization modulating the …

Molecular Interactions Between Pvt1 Transcripts And C-Myc, Onayemi Titilayo Onagoruwa

Theses and Dissertations

This study focused on the molecular relationships between PVT1 exons 4A, 4B, 9 and c-Myc in prostate cancer. Data showed significant regulatory interactions between these exons and c-Myc which is strongest between PVT1 exon 9 and c-Myc. This will likely have implications for PCa where PVT1 and c-Myc are dysregulated.

Allomaternal Care By Conspecifics Impacts Activity Budgets Of Colobus Guereza Mothers, Dominique L. Raboin

Theses and Dissertations

In primate societies, caring for infants involves nursing, protection, provisioning, and carrying - all energetically taxing states for mothers. The cost of holding and carrying clinging infants often constrains mothers from moving and traveling, potentially reducing their food and energy intake. Alternatively, when an infant is physically separated from their mother they are at risk of predation from birds of prey or other large mammals. This requires a high level of vigilance from mothers, often further deterring them from acquiring the food and energy that they need. Allomaternal care (AMC) is hypothesized to provide mothers with a way to safely …

Exoskeleton Assistance Symmetry Matters: Unilateral Assistance Reduces Metabolic Cost, But Relatively Less Than Bilateral Assistance, Philippe Malcolm, Samuel Galle, Pieter Van Den Berghe, Dirk De Clercq

Journal Articles

Background: Many gait impairments are characterized by asymmetry and result in reduced mobility. Exoskeletons could be useful for restoring gait symmetry by assisting only one leg. However, we still have limited understanding of the effects of unilateral exoskeleton assistance. Our aim was to compare the effects of unilateral and bilateral assistance using a within-subject study design.

Methods: Eleven participants walked in different exoskeleton conditions. In the Unilateral conditions, only one leg was assisted. In Bilateral Matched Total Work, half of the assistance from the Unilateral conditions was applied to both legs such that the bilateral sum was equal …

Soil Erodibility Differs According To Heritable Trait Variation And Nutrient-Induced Plasticity In The Salt Marsh Engineer Spartina Alterniflora, Brittany M. Bernik, John H. Pardue, Michael J. Blum

Faculty Publications

Use of landform engineers for habitat restoration has often resulted in unanticipated outcomes. It is possible that departures from expectation arise because applications do not adequately account for the influence of heritable and non-heritable phenotypic variation on ecosystem attributes. In this study, we performed a common garden greenhouse experiment to determine whether soil shear strength—a characteristic linked to erosion resistance—varies according to heritable and plastic trait expression in Spartina alterniflora grown under contrasting nutrient regimes. We detected heritable variation across a broad spectrum of functional traits, including nutrient uptake. We also found that S. alterniflora exhibited trait-specific differences in nutrient-induced …

Functioning Religiously, Brent A. Smith

Open Access Publishing Support Funded Articles

No abstract provided.

La Sal Daisy, Erigeron Mancus, Density And Associated Species From Treeline Ecotone And Alpine Habitats, James F. Fowler, Steve Overby, Barb Smith

Western North American Naturalist

The La Sal daisy, Erigeron mancus, is endemic to treeline ecotone and alpine meadow habitats of the La Sal Mountains in Utah, an insular, laccolithic mountain range on the Colorado Plateau in southeastern Utah. From 2009 to 2011 we established elevational transects through upper spruce-fir forest, treeline ecotone, and alpine meadow habitats on Laurel Ridge in the Middle Mountain group of the La Sal Mountains to measure (1) periodic changes in E. mancus population density, (2) changes in the elevation of the E. mancus population centroid, (3) changes in patch size occupied by E. mancus, and (4) changes …

Interaction Between Seed Detectability And Seed Preference Affects Harvest Rates Of Granivorous Rodents, William S. Longland, Lindsay A. Dimitri

Western North American Naturalist

Granivorous rodents commonly exhibit preferences for seeds of particular plant species. However, among buried seeds that are available, rodents may find that alternate, less desirable seeds are more easily located by olfaction than preferred seeds. Seeds of Indian ricegrass (Achnatherum hymenoides) are a highly preferred food resource for seed-caching desert heteromyid rodents. We tested relative abilities of heteromyids to locate buried caches of Indian ricegrass seeds versus seeds of another plant species (cheatgrass, Bromus tectorum) that are common in heteromyid diets at a western Nevada field site. Rodents located more cheatgrass than Indian ricegrass seed caches in …

Front Matter, Vol. 78 No. 2

Western North American Naturalist

No abstract provided.

End Matter, Vol. 78 No. 2

Western North American Naturalist

No abstract provided.

Cougar Dispersal And Natal Homing In A Desert Environment, David M. Choate, Kathleen M. Longshore, Daniel B. Thompson

Life Sciences Faculty Research

We present a review of cougar dispersal literature and the first evidence of natural (i.e., unmanipulated) homing behavior by a dispersing male cougar (Puma concolor) that sustained severe injuries crossing the northern Mojave Desert. Based on Global Positioning System and ground tracking data, the male traveled a total distance of 981.1 km at 5.03 km/d, including 170.31 km from the Desert National Wildlife Refuge to the northwestern Grand Canyon, where he sustained severe injuries. The interkill interval increased from 7.1 ± 2.7 d while he was in his natal range to 17.5 ± 4.9 d during dispersal. While homing, the …

Does Physiology Play A Role In Conflict?: Exploring The Associations Between Testosterone, Accommodation, And Relationship Variables, Anuraj Dhillon

Doctoral Dissertations

Recent investigations have focused on exploring the role of physiology in human communication, yet a plethora of work is required to better understand how physiology affects or is affected by relational communication and the present investigation contributes to this body of research. This study combined the tenets of communication accommodation theory (CAT), relational uncertainty, and steroid/peptide theory of social bonds (S/P theory) to examine the role of testosterone (T) in romantic partners’ conflict conversation behaviors. More specifically, the study proposed that T moderates the association between romantic partners use of (non)accommodation during conflict conversations and relational uncertainty, which in turn …

Icp8 Self Interactions Are Essential For Hsv-1 Replication Compartment Formation, Anthar Darwish

Doctoral Dissertations

Archival abstract submitted

Identification Of Enhanced Ifn-Γ Signaling In Polyarticular Juvenile Idiopathic Arthritis With Mass Cytometry, Allison A Throm, Halima Moncrieffe, Amir B Orandi, Jeanette T Pingel, Theresa L Geurs, Hannah L Miller, Allyssa L Daugherty, Olga N Malkova, Daniel J Lovell, Susan D Thompson, Alexei A Grom, Megan A Cooper, Stephen T Oh, Anthony R French

Open Access Publications

Polyarticular juvenile idiopathic arthritis (JIA) is among the most challenging of the JIA subtypes to treat. Even with current biologic therapies, the disease remains difficult to control in a substantial subset of patients, highlighting the need for new therapies. The aim of this study was to use the high dimensionality afforded by mass cytometry with phospho-specific antibodies to delineate signaling abnormalities in immune cells from treatment-naive polyarticular JIA patients. Peripheral blood mononuclear cells were isolated from 17 treatment-naive polyarticular JIA patients, 10 of the patients after achieving clinical remission, and 19 healthy controls. Samples were stimulated for 15 minutes with …

Cardiovascular Consequences Of Katp Overactivity In Cantu Syndrome, Yan Huang, Conor Mcclenaghan, Theresa M Harter, Kristina Hinman, Carmen M Halabi, Scot J Matkovich, Haixia Zhang, G Schuyler Brown, Robert P Mecham, Sarah K England, Attila Kovacs, Maria S Remedi, Colin G Nichols

Open Access Publications

Cantu syndrome (CS) is characterized by multiple vascular and cardiac abnormalities including vascular dilation and tortuosity, systemic hypotension, and cardiomegaly. The disorder is caused by gain-of-function (GOF) mutations in genes encoding pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunits. However, there is little understanding of the link between molecular dysfunction and the complex pathophysiology observed, and there is no known treatment, in large part due to the lack of appropriate preclinical disease models in which to test therapies. Notably, expression of Kir6.1 and SUR2 does not fully overlap, and the relative contribution of KATP GOF in …

3-Hydroxy-2-(4- Methylphenyl)-4h-Chromen-4-One, Clifford W. Padgett, Will E. Lynch, Kirkland Sheriff, Raven Dean, Sarah Zingales

Chemistry: Faculty Publications (1990-2023)

Our work in the area of carbon-monoxide-releasing mol­ecules led to the synthesis and crystallization of new flavone derivatives as inter­mediates. Herein we report the first crystal structure of the title compound, C16H12O3, a hy­droxy-substituted flavone where the 2-phenyl group has been replaced by a p-tolyl group. The introduction of the 3-hy­droxy group allows the formation of inter­molecular O—H...O=C hydrogen bonds, used to build centrosymmetric R22(10) ring motifs in the crystal.

Pubh 6532-A – Environmental Health, Asli Aslan

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed for graduate students and provides students with an introduction and overview of the key areas of environmental health. Students will gain an understanding of the interaction of individuals and communities with the environment. Impact of environmental agents on human and ecosystem health will be analyzed. This course will also introduce current topics in global environmental health and challenges faced under the changing climate and socio-economic needs and examine recent case studies and their outcomes related to environmental policy and management.

Sex Differences In Individual Foraging Site Fidelity Of Campbell Albatross, Lisa A. Sztukowski, Peter A. Cotton, Henri Weimerskirch, David R. Thompson, Leigh G. Torres, Paul M. Sagar, Antony M. Knights, Annette L. Fayet, Stephen C. Votier

School of Biological and Marine Sciences

Inter-individual variation in behavioural traits has important implications for evolutionary and ecological processes. Site fidelity, where individuals consistently use the same foraging site, is common among marine predators. Sex differences in foraging are also well studied in marine vertebrates, but the extent to which consistent inter-individual differences in foraging vary between the sexes is poorly known. Here we quantified the effects of sex on individual foraging site fidelity (IFSF), both within and between years, in chick-brooding Campbell albatross Thalassarche impavida. Using bird-borne global positioning system loggers, we calculated route fidelity (nearest-neighbour distance), repeatability of site fidelity (terminal latitude and longitude), …