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2018

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Implications Of 3-D Printing For Teaching Geoscience Concepts To Students With Visual Impairments, Karen E. Koehler, Tiffany A. Wild, Sean Tikkun Dec 2018

Implications Of 3-D Printing For Teaching Geoscience Concepts To Students With Visual Impairments, Karen E. Koehler, Tiffany A. Wild, Sean Tikkun

Journal of Science Education for Students with Disabilities

This article presents the results of a study on the use of 3-D printed models in a science classroom for students with visual impairments and examines whether the use of these models impacts student conceptual understanding and misconceptions related to geosciences concepts, specifically plate tectonics.

Data were collected one week prior to instruction, one week after instruction and throughout the 3-week instructional period. Results showed that students with visual impairments held many of the same misconceptions about plate tectonics as students who are typically sighted. All students in this study had fewer misconceptions after the instructional period than they held …


Systematics Of Malesian-Pacific Piper (Piperaceae), Rani Asmarayani Dec 2018

Systematics Of Malesian-Pacific Piper (Piperaceae), Rani Asmarayani

Dissertations

Comprised of ~2400 spp., Piper is a major clade in the magnoliid angiosperms. Three major groups are recognized in Piper, i.e., the Neotropical, Asian and South Pacific. Unlike Neotropical Piper,relationships in the Paleotropical Piper remain enigmatic. This study focused on the Paleotropical Piperwith emphasize on the Malesian-Pacific Piper, Malesia being the center of diversity of the genus in the Paleotropics. The goals are to evaluate relationships within Paleotropical Piper (chapter 1), to evaluate characters, morphological (chapter 1) and stem anatomical (chapter 2), that may distinguish clades, and to investigate the species boundaries focusing on the well-supported …


12-11-2018 Swosu Students Scheduled To Complete Degreesafter 2018 Fall Semester, Southwestern Oklahoma State University Dec 2018

12-11-2018 Swosu Students Scheduled To Complete Degreesafter 2018 Fall Semester, Southwestern Oklahoma State University

THE BARK ARCHIVE 2018

A total of 438 students at Southwestern Oklahoma State University in Weatherford complete requirements for either associate, bachelor’s, master’s or doctoral degrees after the 2018 fall semester.


Sr-18-19-14 Cc, Marshall University Dec 2018

Sr-18-19-14 Cc, Marshall University

Recommendations

No abstract provided.


Bariatric Surgery As A Treatment To Obesity, Morgan D. Dunn Dec 2018

Bariatric Surgery As A Treatment To Obesity, Morgan D. Dunn

Health Sciences Student Scholarship

This paper focuses on the efficiency and effectiveness that bariatric surgery provides as a treatment for the obesity epidemic that is ever-growing in our country. By taking into account scientific, ethnographical, scholarly, statistic-based, and various other forms of research, this paper argues for the widespread use of bariatric surgery for weight loss, decrease in obesity, and resolution of obesity comorbidities. This paper also focuses on the various factors that affect patient success in bariatric surgery, such as gaps in access, economic problems, psychological issues associated with the procedure, and more. Nevertheless, bariatric surgery, if these factors are taken into consideration, …


Johnson Lab Part Of Grant To Study Bat And Song Bird Migration, Ohio University College Of Arts & Sciences Dec 2018

Johnson Lab Part Of Grant To Study Bat And Song Bird Migration, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Parental Habituation To Human Disturbance Over Time Reduces Fear Of Humans In Coyote Offspring, Christopher J. Schell, Julie K. Young, Elizabeth V. Lonsdorf, Rachel M. Santymire, Jill M. Mateo Dec 2018

Parental Habituation To Human Disturbance Over Time Reduces Fear Of Humans In Coyote Offspring, Christopher J. Schell, Julie K. Young, Elizabeth V. Lonsdorf, Rachel M. Santymire, Jill M. Mateo

Wildland Resources Faculty Publications

A fundamental tenet of maternal effects assumes that maternal variance over time should have discordant consequences for offspring traits across litters. Yet, seldom are parents observed across multiple reproductive bouts, with few studies consider‐ ing anthropogenic disturbances as an ecological driver of maternal effects. We ob‐ served captive coyote (Canis latrans) pairs over two successive litters to determine whether among‐litter differences in behavior (i.e., risk‐taking) and hormones (i.e., cortisol and testosterone) corresponded with parental plasticity in habituation. Thus, we explicitly test the hypothesis that accumulating experiences of anthropogenic disturbance reduces parental fear across reproductive bouts, which should have disparate phenotypic …


Icc Agenda, December 11, 2018, Individual Course Committee Dec 2018

Icc Agenda, December 11, 2018, Individual Course Committee

Individual Course Committee (ICC)

No abstract provided.


College Of Education News, College Of Education, Georgia Southern University Dec 2018

College Of Education News, College Of Education, Georgia Southern University

College of Education News

  • College of Ed professor receives national Evolution Education Award

  • Education Exposed: A 2019 film series to be offered free to students, community

  • COE alumnus helps land major grant, puts Apple technology in hands of Brock Elementary 2nd, 3rd graders

  • Georgia Southern named No. 1 on master’s in educational leadership rankings


College Voice Vol. 42 No. 6 [December 11, 2018], Connecticut College Dec 2018

College Voice Vol. 42 No. 6 [December 11, 2018], Connecticut College

2018-2019

No abstract provided.


Synchronous Online Tutoring For Deaf And Hard-Of-Hearing Students: An Analysis Of Observed Functions, Lisa B. Elliot, Rebecca Carpenter Dec 2018

Synchronous Online Tutoring For Deaf And Hard-Of-Hearing Students: An Analysis Of Observed Functions, Lisa B. Elliot, Rebecca Carpenter

Presentations and other scholarship

Literature on online learning suggests that many faculty members are reluctant to participate in online learning activities. Concerns raised include faculty concerns that the experiences may be impersonal and that technology will stand in the way of the learning experience. Despite this resistance, students are more likely to endorse online learning strategies, especially because they provide more flexibility in managing complex schedules. Previous research from the Deaf STEM Community Alliance project found that students were positive about their experiences—the opportunity to communicate online enabled students to seek out tutoring that they would not have been able to get otherwise due …


Dhikr (Recitation) And Relaxation Improve Stress Perception And Reduce Blood Cortisol Level In Type 2 Diabetes Mellitus Patients With Oad, Faisal Amir, Gondo Mastutik, M Hasinuddin, Suhartono Taat Putra Dec 2018

Dhikr (Recitation) And Relaxation Improve Stress Perception And Reduce Blood Cortisol Level In Type 2 Diabetes Mellitus Patients With Oad, Faisal Amir, Gondo Mastutik, M Hasinuddin, Suhartono Taat Putra

Folia Medica Indonesiana

Recitation and relaxation are translated as stimuli that can turn disstraints into uneven conditions (balanced conditions). The purpose of this study was to explain the effect of remembrance and relaxation on improving stress perception and decreasing blood cortisol levels in patients with type 2 diabetes mellitus with Anti Diabetes Medication (OAD). This type of research is quasi-experimental with the non randomized control group pretest posttest design. The population in this study were all type 2 diabetes mellitus patients at the Internal Poly department of Syarifah Ambami Hospital Rato Ebu Bangkalan. The study sample was divided into 2 groups, namely control …


The Prevalence Of Extended Spectrum Beta-Lactamase (Esbl) Producing Gut Bacterial Flora Among Patients In Dr. Soetomo Hospital And Primary Health Centre In Surabaya, Dian Neni Naelasari, Eko Budi Koendhori, Linda Dewanti, Rosantia Sarassari, K Kuntaman Dec 2018

The Prevalence Of Extended Spectrum Beta-Lactamase (Esbl) Producing Gut Bacterial Flora Among Patients In Dr. Soetomo Hospital And Primary Health Centre In Surabaya, Dian Neni Naelasari, Eko Budi Koendhori, Linda Dewanti, Rosantia Sarassari, K Kuntaman

Folia Medica Indonesiana

The extended-spectrum b-lactamase (ESBL) producer bacteria until now were mostly identified in hospital environment. The aim of this study was to analyze the prevalence of ESBL-producing gut flora and distribution of ESBL encoding genes between hospitalized patient in Tropical Wards of Dr. Soetomo Hospital and patient from a primary health centre (PHC) as community environment in Surabaya. Thiry rectal swab samples from hospital of Dr. Soetomo patients and from PHC (60 samples in total) were collected for this study. Samples were screened in MacConkey agar supplemented with 2 mg/L of cefotaxim, incubated at 37ºC for 24 hours. Then the growing …


The Efficacy Of Psidium Guajava Linn Leaf Extractsfrom Selangor Region Against Gram-Positive And Gram-Negative Bacteria, S Zuhaira, Noorhaniz Mohd Nizam, Pm Ridzuan Dec 2018

The Efficacy Of Psidium Guajava Linn Leaf Extractsfrom Selangor Region Against Gram-Positive And Gram-Negative Bacteria, S Zuhaira, Noorhaniz Mohd Nizam, Pm Ridzuan

Folia Medica Indonesiana

Antibiotic is a type of medication that helps in fighting bacterial infection. Treating bacterial infections in clinical setting become more complicated and costly due to drug resistance. This study was conducted to determine the antibacterial potential of Psidium guajava Linn leaf extracts against Gram-positive and Gram-negative bacteria. P. guajava Linn leaf was obtained from Research Orchards at University Putra Malaysia (UPM). Leaves were extracted using three types of extracts; hot, cold and methanol extract. Freeze dried was used in this study and temperature was set at -104°C for 24 hours. Antibacterial testing was determined using disc diffusion and well diffusion …


Approved Courses, December 11, 2018, Individual Course Committee Dec 2018

Approved Courses, December 11, 2018, Individual Course Committee

Individual Course Committee (ICC)

No abstract provided.


Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi Dec 2018

Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi

Faculty Publications

The U. S. Gulf of Mexico is experiencing a dramatic increase in tidal marsh restoration actions, which involves planting coastal areas with smooth cordgrass (Spartina alterniflora) and black needlerush (Juncus roemerianus) for erosion control and to provide habitat for fish and wildlife. It can take decades for sedimentary cycles in restored marshes to approach reference conditions, and the contribution of the sediment microbial communities to these processes is poorly elucidated. In this study, we addressed this gap by comparing rhizosphere microbiomes of S. alterniflora and J. roemerianus from two restored marshes and a natural reference marsh located at Deer Island, …


Phylogeographic Analyses Of A Widely Distributed Populus Davidiana: Further Evidence For The Existence Of Glacial Refugia Of Cool‐Temperate Deciduous Trees In Northern East Asia, Zhe Hou, Zhaoshan Wang, Zhanyang Ye, Shuhui Du, Shuya Liu, Jianguo Zhang Dec 2018

Phylogeographic Analyses Of A Widely Distributed Populus Davidiana: Further Evidence For The Existence Of Glacial Refugia Of Cool‐Temperate Deciduous Trees In Northern East Asia, Zhe Hou, Zhaoshan Wang, Zhanyang Ye, Shuhui Du, Shuya Liu, Jianguo Zhang

Aspen Bibliography

Despite several phylogeographic studies had provided evidence to support the existence of glacial refugia of cool‐temperate deciduous trees in northeast China, the species used in these studies were limited by the species ranges, which could not exclude the possibility that northern populations were the colonists from southern refugial populations during the last glacial maximum (LGM). Here, we estimated the nucleotide variation in Populus davidiana, a widespread species distributed in Eurasia. Three groups in northeast, central, and southwest China were constructed according to the simulation results from SAMOVA, composition of chloroplast haplotypes and structure results. We revealed that the northeast …


An Explorational Study Of Educational Leaders' Attitudes, Opinions, Understanding, And Application Of Student Growth Percentile (Sgp) Data, J Lyn Turnell Dec 2018

An Explorational Study Of Educational Leaders' Attitudes, Opinions, Understanding, And Application Of Student Growth Percentile (Sgp) Data, J Lyn Turnell

Doctor of Education in Educational Leadership Dissertations

Student Growth Percentiles have recently become popular as a way to report student progress over time. Because of the perception that they are relatively simple to understand, they have also become a popular tool to use when evaluating teachers and school-based administrators, even though this is not the purpose of their design. Previous studies have examined the impact of student growth measures on teachers who are evaluated annually with a tool that includes a component of student growth. This study builds on the previous work of Clauser, Keller, and McDermott (2016) and Collins (2014). It examines the actions and opinions …


Impact Of Individual Traits, Saturated Fat, And Protein Source On The Gut Microbiome., Jennifer M Lang, Calvin Pan, Rita M Cantor, W H Wilson Tang, Jose Carlos Garcia-Garcia, Ira Kurtz, Stanley L Hazen, Nathalie Bergeron, Ronald M Krauss, Aldons J Lusis Dec 2018

Impact Of Individual Traits, Saturated Fat, And Protein Source On The Gut Microbiome., Jennifer M Lang, Calvin Pan, Rita M Cantor, W H Wilson Tang, Jose Carlos Garcia-Garcia, Ira Kurtz, Stanley L Hazen, Nathalie Bergeron, Ronald M Krauss, Aldons J Lusis

Faculty Publications & Research of the TUC College of Pharmacy

Interindividual variation in the composition of the human gut microbiome was examined in relation to demographic and anthropometric traits, and to changes in dietary saturated fat intake and protein source. One hundred nine healthy men and women aged 21 to 65, with BMIs of 18 to 36, were randomized, after a two-week baseline diet, to high (15% total energy [E])- or low (7%E)-saturated-fat groups and randomly received three diets (four weeks each) in which the protein source (25%E) was mainly red meat (beef, pork) (12%E), white meat (chicken, turkey) (12%E), and nonmeat sources (nuts, beans, soy) (16%E). Taxonomic characterization using …


Transcription Factor Duo1 Generated By Neo-Functionalization Is Associated With Evolution Of Sperm Differentiation In Plants, Asuka Higo, Tomokazu Kawashima, Michael Borg, Mingmin Zhao, Irene López-Vidriero, Hidetoshi Sakayama, Sean A. Montgomery, Hiroyuki Sekimoto, Dieter Hackenberg, Masaki Shimamura, Tomoaki Nishiyama, Keiko Sakakibara, Yuki Tomita, Taisuke Togawa, Kan Kunimoto, Akihisa Osakabe, Yutaka Suzuki, Katsuyuki T. Yamato, Kimitsune Ishizaki, Ryuichi Nishihama, Takayuki Kohchi, José M. Franco-Zorrilla, David Twell, Frédéric Berger, Takashi Araki Dec 2018

Transcription Factor Duo1 Generated By Neo-Functionalization Is Associated With Evolution Of Sperm Differentiation In Plants, Asuka Higo, Tomokazu Kawashima, Michael Borg, Mingmin Zhao, Irene López-Vidriero, Hidetoshi Sakayama, Sean A. Montgomery, Hiroyuki Sekimoto, Dieter Hackenberg, Masaki Shimamura, Tomoaki Nishiyama, Keiko Sakakibara, Yuki Tomita, Taisuke Togawa, Kan Kunimoto, Akihisa Osakabe, Yutaka Suzuki, Katsuyuki T. Yamato, Kimitsune Ishizaki, Ryuichi Nishihama, Takayuki Kohchi, José M. Franco-Zorrilla, David Twell, Frédéric Berger, Takashi Araki

Plant and Soil Sciences Faculty Publications

Evolutionary mechanisms underlying innovation of cell types have remained largely unclear. In multicellular eukaryotes, the evolutionary molecular origin of sperm differentiation is unknown in most lineages. Here, we report that in algal ancestors of land plants, changes in the DNA-binding domain of the ancestor of the MYB transcription factor DUO1 enabled the recognition of a new cis-regulatory element. This event led to the differentiation of motile sperm. After neo-functionalization, DUO1 acquired sperm lineage-specific expression in the common ancestor of land plants. Subsequently the downstream network of DUO1 was rewired leading to sperm with distinct morphologies. Conjugating green algae, a …


‘Profiles In Faculty Achievement’ Video Spotlights Ohio’S Jodie Foster (December 11, 2018), University Communications And Marketing Dec 2018

‘Profiles In Faculty Achievement’ Video Spotlights Ohio’S Jodie Foster (December 11, 2018), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.


Agenda, December 11, 2018, Programs Committee Dec 2018

Agenda, December 11, 2018, Programs Committee

Programs Committee (PC)

No abstract provided.


Approved Programs, December 11, 2018, Programs Committee Dec 2018

Approved Programs, December 11, 2018, Programs Committee

Programs Committee (PC)

No abstract provided.


Increased Activity Of Mature Osteoblast From Rat Bone Marrow-Mesenchymal Stem Cells Tn Osteogenic Medium Exposed To Melatonin, Yugi Hari Chandra Purnama, Gondo Mastutik, Suhartono Taat Putra Dec 2018

Increased Activity Of Mature Osteoblast From Rat Bone Marrow-Mesenchymal Stem Cells Tn Osteogenic Medium Exposed To Melatonin, Yugi Hari Chandra Purnama, Gondo Mastutik, Suhartono Taat Putra

Folia Medica Indonesiana

Exposure to melatonin in the cultures of Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in osteogenic medium is able to induce mesenchymal stem cells and preosteoblasts into active osteoblasts via several transduction signals such as ERK 1/2. Previous studies used a single dose of 50 nM and a physiological dose of 20-200 pg/ml. The objective of the study was to obtain an optimal dose of melatonin that enhances osteoblast activity by increasing the expression of ERK1/2 and ALP levels in the culture of Rat Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in osteogenic medium. This study was an in vitro experimental laboratory …


Exploring Structure-Property Relationships Of Gags To Tailor Ecm-Mimicking Hydrogels, Ralf Zimmermann, Carsten Werner, James Sterling Dec 2018

Exploring Structure-Property Relationships Of Gags To Tailor Ecm-Mimicking Hydrogels, Ralf Zimmermann, Carsten Werner, James Sterling

Business and Information Technology Faculty Research & Creative Works

Glycosaminoglycans (GAGs) are a class of linear polysaccharides that are ubiquitous in the extracellular matrix (ECM) and on cell surfaces. Due to their key role in development, homeostasis, pathogenesis, and regeneration, GAGs are increasingly used in the design of ECM-mimicking hydrogels to stimulate tissue formation and regenerative processes via specifically orchestrated cell-instructive signals. These applications first and foremost build on the ability of GAGs to effectively bind, protect, and release morphogens. The specificity and strength of morphogen-GAG interactions are largely governed by the number and spatial distribution of negatively charged sulfate groups carried by GAGs. Herein, we summarize a mean-field …


Poly(Lactic Acid) (Pla), Poly(-Caprolactone) (Pcl) And Thermoplastic Starch (Tps) Blends For Compostable Packaging Applications, Rui Wang Dec 2018

Poly(Lactic Acid) (Pla), Poly(-Caprolactone) (Pcl) And Thermoplastic Starch (Tps) Blends For Compostable Packaging Applications, Rui Wang

Theses

The increasing severe plastic issue has brought the biodegradable polymers into the top researching field. The various bioplastics become a promising way to reduce the solid waste and boost the sustainable development of the world. This study focused on the performance of ternary blend of PLA, PCL and TPS. All these three materials are playing an essential role in the bioplastic industry due to their outstanding properties and 100% biodegradable. However, the drawbacks of each material limited its application in packaging. This study aimed to overcome the shortcomings by blending PLA, PCL and TPS in an optimal composition, and proper …


Cryo-Em Structures Of Eastern Equine Encephalitis Virus Reveal Mechanisms Of Virus Disassembly And Antibody Neutralization, Saif Hasan, Chengqun Sun, Arthur S. Kim, Yasunori Watanabe, Chun-Liang Chen, Thomas Klose, Geeta Buda, Max Crispin, Michael S. Diamond, William B. Klimstra, Michael G. Rossmann Dec 2018

Cryo-Em Structures Of Eastern Equine Encephalitis Virus Reveal Mechanisms Of Virus Disassembly And Antibody Neutralization, Saif Hasan, Chengqun Sun, Arthur S. Kim, Yasunori Watanabe, Chun-Liang Chen, Thomas Klose, Geeta Buda, Max Crispin, Michael S. Diamond, William B. Klimstra, Michael G. Rossmann

Department of Biological Sciences Faculty Publications

Alphaviruses are enveloped pathogens that cause arthritis and encephalitis. Here, we report a 4.4-Å cryoelectron microscopy (cryo-EM) structure of eastern equine encephalitis virus (EEEV), an alphavirus that causes fatal encephalitis in humans. Our analysis provides insights into viral entry into host cells. The envelope protein E2 showed a binding site for the cellular attachment factor heparan sulfate. The presence of a cryptic E2 glycan suggests how EEEV escapes surveillance by lectin-expressing myeloid lineage cells, which are sentinels of the immune system. A mechanism for nucleocapsid core release and disassembly upon viral entry was inferred based on pH changes and capsid …


Occurrence Of Alkaloids In Grass Seeds Symbiotic With Vertically-Transmitted Epichloë Fungal Endophytes And Its Relationship With Antioxidants, Pedro E. Gundel, Charlotte E. Seal, Fernando Biganzoli, Marco A. Molina-Montenegro, Beatriz R. Vázquez-De-Aldana, Iñigo Zabalgogeazcoa, Lowell P. Bush, María A. Martínez-Ghersa, Claudio M. Ghersa Dec 2018

Occurrence Of Alkaloids In Grass Seeds Symbiotic With Vertically-Transmitted Epichloë Fungal Endophytes And Its Relationship With Antioxidants, Pedro E. Gundel, Charlotte E. Seal, Fernando Biganzoli, Marco A. Molina-Montenegro, Beatriz R. Vázquez-De-Aldana, Iñigo Zabalgogeazcoa, Lowell P. Bush, María A. Martínez-Ghersa, Claudio M. Ghersa

Plant and Soil Sciences Faculty Publications

Host organisms can acquire new functional traits through symbiosis. Seed-transmitted Epichloë fungal endophytes are known to protect host plants against herbivores and increase tolerance to abiotic stresses by alkaloids and antioxidants, respectively (currencies of mutualism). Whereas, alkaloids are fungal products with demonstrated effects at plant vegetative stage, few studies have focused on alkaloids in seeds. We assessed the occurrence of fungal alkaloids and determined their concentrations in seeds of two host grasses, Festuca rubra and Lolium multiflorum. Then, we sought for a relationship with the antioxidants tocochromanols and glutathione, which are involved in the control of oxidative stress. Different …


Schinus Molle: Anatomy Of Leaves And Stems, Chemical Composition And Insecticidal Activities Of Volatile Oil Against Bed Bug (Cimex Lectularius), Cms Collaboration, J. G. Acosta, S. Oliveros Dec 2018

Schinus Molle: Anatomy Of Leaves And Stems, Chemical Composition And Insecticidal Activities Of Volatile Oil Against Bed Bug (Cimex Lectularius), Cms Collaboration, J. G. Acosta, S. Oliveros

Faculty and Student Publications (Open Access)

No abstract provided.


Gofish: A Versatile Nested Pcr Strategy For Environmental Dna Assays For Marine Vertebrates, Mark Y. Stoeckle, Mithun Das Mishu, Zachary Charlop-Powers Dec 2018

Gofish: A Versatile Nested Pcr Strategy For Environmental Dna Assays For Marine Vertebrates, Mark Y. Stoeckle, Mithun Das Mishu, Zachary Charlop-Powers

Publications and Research

Here we describe GoFish, a strategy for single-species environmental DNA (eDNA) presence/absence assays using nested PCR. The assays amplify a mitochondrial 12S rDNA segment with vertebrate metabarcoding primers, followed by nested PCR with M13-tailed, species-specific primers. Sanger sequencing confirms positives detected by gel electrophoresis. We first obtained 12S sequences from 77 fish specimens for 36 northwestern Atlantic taxa not well documented in GenBank. Using these and existing 12S records, we designed GoFish assays for 11 bony fish species common in the lower Hudson River estuary and tested seasonal abundance and habitat preference at two sites. Additional assays detected nine cartilaginous …