Digital Commons Network^™

The Optimization Of Emergency Response For Oil Spill In Wusongkou Waters, Fei Hong

Maritime Safety & Environment Management Dissertations (Dalian)

No abstract provided.

Morris And Graduate Students Present At Animal Behavior Society Meetings, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Plant Club Offers Hiking Camaraderie Conservation And Professional Development, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Food Studies Kicks Off Fall With Student Farm Brewing Course, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Ohio Researchers Called Upon To Solve Midge Fly Infestation In Ohio Waste Water Treatment Plants, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Perbandingan Metode Uji Aktivitas Antioksidan Dpph, Frap Dan Fic Terhadap Asam Askorbat, Asam Galat Dan Kuersetin, Kiki Maesaroh, Dikdik Kurnia, Jamaludin Al Anshori

Chimica et Natura Acta

Antioksidan merupakan senyawa yang menghambat atau menunda reaksi oksidasi molekul dengan cara menghambat proses inisiasi atau propagasi reaksi oksidasi berantai. Struktur kimiawi antioksidan, sumber radikal bebas, dan sifat fisiko-kimia sediaan sampel yang berbeda dapat memberikan hasil uji aktivitas antioksidan yang beragam. Oleh karena itu, diperlukan suatu metode analisa aktivitas antioksidan yang selektif untuk suatu jenis sampel tertentu. Studi perbandingan metode uji aktivitas antioksidan DPPH, FRAP, dan FIC telah dilakukan terhadap asam askorbat (AA), asam galat (AG), dan kuersetin. Ketiga metode uji antioksidan dibedakan berdasarkan pada jenis mekanisme reaksinya, sedangkan sampel standar antioksidan dipilih berdasarkan struktur polihidroksi atau polifenol yang umumnya …

Comparative Study Of References And Protein Quantifications Using Biuret-Spectrophotometric Method, Ahmad Syauqi, Muhamad Fuadi, Hari Santoso

Chimica et Natura Acta

Comparison between the references and the quantification of biuret standard curves can be performed using statistical methods. The objective of this study was to select a method of protein quantification of the biuret-spectrophotometric based on the similar standard curve of the compound. The study used experimental methods in the laboratory and references from a comparative scheme of mean that has categories of statistics called academic and practical terms. Two standard curves were tested with the reference data. The academic way was performed with a comparison of 11.779-12.401% confidence, and the quantification of the results of the protein mean of 8.211% …

Evaluating The Effectiveness Of A Focused Debate On The Development Of Ethical Reasoning Skills In Pharmacy Technician Students., Seana Hogan, Julie Dunne

Articles

Objective. To evaluate the effectiveness of debating an ethical dilemma on the development of ethical reasoning skills in pharmacy technician students.

Methods. A mixture of qualitative and quantitative methods was used. This included analysis of before and after 5-minute papers, a sentiment survey, thematic analysis of student reflective writing and a qualitative questionnaire by an independent observer.

Results. Twenty-five students participated in the study. The 5-minute papers showed improvement in student learning. In the sentiment survey, 83% of students agreed or strongly agreed that they had a better understanding of ethical dilemmas following the debate. The main theme identified from …

A Hybrid Lagrangian–Eulerian Particle Model For Ecosystem Simulation, Pengfei Xue, David J. Schwab, Xing Zhou, Chenfu Huang, Ryan Kibler, Xinyu Ye

Michigan Tech Publications, Part 1

Current numerical methods for simulating biophysical processes in aquatic environments are typically constructed in a grid-based Eulerian framework or as an individual-based model in a particle-based Lagrangian framework. Often, the biogeochemical processes and physical (hydrodynamic) processes occur at different time and space scales, and changes in biological processes do not affect the hydrodynamic conditions. Therefore, it is possible to develop an alternative strategy to grid-based approaches for linking hydrodynamic and biogeochemical models that can significantly improve computational efficiency for this type of linked biophysical model. In this work, we utilize a new technique that links hydrodynamic effects and biological processes …

Nutrition Education To Improve Health Outcomes In Community Dwelling Older Adults, Sara Giessinger

Master's Projects and Capstones

Abstract

The proportion of people age 60 and over is growing faster than other age group, and will double by 2050 from approximately 605 million to 2 billion worldwide, in addition to the 80 and over population quadrupling by the same time. Non-communicable diseases such as obesity, cancer, coronary heart and lung disease, diabetes, hypertension, insulin resistance, and hyperlipidemia,represent 63% of deaths annually worldwide. Due to the immense contact nurses have with clients, they play a key role in screening, referrals and education to guide this demographic to improved health outcomes through nutrition and physical activity interventions (Xiaoyue, Parker, Ferguson, …

Studi Perbandingan Kinerja Serbuk Dan Arang Biji Salak Pondoh (Salacca Zalacca) Pada Adsorpsi Metilen Biru, Dwi I. Hikmawati

Chimica et Natura Acta

Pembuatan adsorben dengan memanfaatkan limbah biomassa terus dilakukan dalam rangka memperoleh material alternatif yang memiliki efektifitas tinggi. Adsorben seharusnya dibuat dari material yang mudah diperoleh, proses pembuatan mudah, ramah lingkungan, biaya operasional rendah, dan dapat diperbaharui. Dalam penelitian ini, adsorben berbasis biomassa berhasil dibuat dengan dua variasi, yaitu serbuk biji (SSzM) dan arang biji (SSzC) salak pondoh (Salacca zalacca). Masing-masing adsorben dikarakterisasi menggunakan FTIR untuk mengetahui gugus fungsi yang terdapat di permukaan padatan. Hasil karakterisasi menunjukkan bahwa SSzM dan SSzC memiliki kemiripan serapan dengan beberapa pergeseran bilangan gelombang dan perbedaan intensitas puncak. Kinerja adsorben diuji untuk adsorpsi larutan metilen biru …

Kulit Salak Sebagai Biosorben Potensial Untuk Pengolahan Timbal(Ii) Dan Cadmium(Ii) Dalam Larutan, Rahmiana Zein, Novrizaldi Wardana, Refilda Refilda, Hermansyah Aziz

Chimica et Natura Acta

Biosorben dari kulit salak (Salacca sumatrana) digunakan untuk mempelajari penyerapan Pb(II) dan Cd(II) dalam larutan dengan metode batch. Adsorpsi Pb(II) dan Cd(II) menggunakan kulit salak ini dipelajari pada variasi pH, konsentrasi adsorbat dan waktu kontak. Kondisi optimum penyerapan yang diperoleh pH 4 untuk Pb(II) dan 5 untuk Cd(II), konsentrasi adsorbat 1200 mg/L untuk Pb(II) dan 800 mg/L untuk Cd(II), waktu kontak 45 menit untuk Pb(II) dan 15 menit untuk Cd(II). Kapasitas penyerapan dari biosorben kulit salak sebesar 83,33 mg/g untuk Pb(II) dan 27,78 mg/g untuk Cd(II) dengan pola adsorpsi mengikuti isoterm Langmuir dengan koefisien determinasi 0,987 dan 0,937 dan data …

Kualitas Warna Benih Ikan Mas Koki (Carassius Auratus) Oranda Pada Berbagai Tingkat Pemberian Tepung Spirulina Platensis, Yuli Andriani, Tia Rostiana Siti Maesaroh, Ayi Yustiati, Iskandar Iskandar, Irfan Zidni

Chimica et Natura Acta

Warna yang cemerlang merupakan salah satu parameter kualitas dan nilai jual pada ikan koki Oranda (Carassius auratus). Karotenoid merupakan komponen alami dalam pembentuk pigmen warna yang memberikan pengaruh cukup baik terhadap warna orange pada ikan koki. Penelitian ini bertujuan untuk mengetahui pengaruh tingkat pemberian tepung Spirulina platensis terhadap kecerahan warna benih ikan mas koki. Penelitian ini dilaksanakan pada bulan Februari – April 2017 di Laboratorium Akuakultur Gedung 2 Fakultas Perikanan dan Ilmu Kelautan Universitas Padjadjaran. Metode yang digunakan adalah eksperimen dengan Rancangan Acak Lengkap (RAL) yang terdiri dari 6 perlakuan dan 3 kali ulangan. Keenam perlakauan tersebut adalah pemberian tepung …

Random Forest Vs Logistic Regression: Binary Classification For Heterogeneous Datasets, Kaitlin Kirasich, Trace Smith, Bivin Sadler

SMU Data Science Review

Selecting a learning algorithm to implement for a particular application on the basis of performance still remains an ad-hoc process using fundamental benchmarks such as evaluating a classifier’s overall loss function and misclassification metrics. In this paper we address the difficulty of model selection by evaluating the overall classification performance between random forest and logistic regression for datasets comprised of various underlying structures: (1) increasing the variance in the explanatory and noise variables, (2) increasing the number of noise variables, (3) increasing the number of explanatory variables, (4) increasing the number of observations. We developed a model evaluation tool capable …

Minimizing The Perceived Financial Burden Due To Cancer, Hassan Azhar, Zoheb Allam, Gino Varghese, Daniel W. Engels, Sajiny John

SMU Data Science Review

In this paper, we present a regression model that predicts perceived financial burden that a cancer patient experiences in the treatment and management of the disease. Cancer patients do not fully understand the burden associated with the cost of cancer, and their lack of understanding can increase the difficulties associated with living with the disease, in particular coping with the cost. The relationship between demographic characteristics and financial burden were examined in order to better understand the characteristics of a cancer patient and their burden, while all subsets regression was used to determine the best predictors of financial burden. Age, …

Identifying Areas For Change: A Case Study On North Carolina State Public School Performance, Olivia Leeson, Kelly Bean, Jacob Drew

SMU Data Science Review

In this paper, we present a framework to identify school-level factors within North Carolina public school administration’s control that have a positive impact on school performance. Public school administrators struggle to improve the academic performance of their schools, as the most influential factors determining overall school performance are outside of their scope of influence. We consider the current circumstances responsible for poor performance in North Carolina public schools and their implications for future academic improvement. Our framework utilizes an extreme gradient boosting model to predict school performance scores using only school-level features that administrators can impact. By varying the inputs, …

The Development Of Young Children’S Social Identity In An Era Of Digital Tools, Sharon Rochelle Kaplan-Berkley

Educational Studies Dissertations

The advancement of innovative digital technologies has created a generation of digital natives (children) growing up in a diverse environment designed by a population of digital immigrants (adults). Consequently, this everyday experience has created some dissonance in their lifestyles, raising questions for educational leaders. The purpose of this mini-ethnographic case study was to develop a deeper understanding of how engaging with digital tools shapes the social interactions of young children, and to examine the various ways online/offline social environments influence face-to-face social peer group formation and functioning. Furthermore, this study explored whether digital technology influences the developing social identities of …

Mobile Elements Shape Plastome Evolution In Ferns, Tanner A. Robison, Amanda L. Grusz, Paul G. Wolf, Jeffrey P. Mower, Blake D. Fauskee, Karla Sosa, Eric Schuettpelz

Biology Faculty Publications

Plastid genomes display remarkable organizational stability over evolutionary time. From green algae to angiosperms, most plastid genomes are largely collinear, with only a few cases of inversion, gene loss, or, in extremely rare cases, gene addition. These plastome insertions are mostly clade-specific and are typically of nuclear or mitochondrial origin. Here, we expand on these findings and present the first family-level survey of plastome evolution in ferns, revealing a novel suite of dynamic mobile elements. Comparative plastome analyses of the Pteridaceae expose several mobile open reading frames that vary in sequence length, insertion site, and configuration among sampled taxa. Even …

Mirna-205 Nanoformulation Sensitizes Prostate Cancer Cells To Chemotherapy, Prashanth K.B. Nagesh, Pallabita Chowdhury, Elham Hatami, Vijaya K. N. Boya, Vivek K. Kashyap, Sheema Khan, Bilal B. Hafeez, Subhash C. Chauhan, Meena Jaggi, Murali M. Yallapu

School of Medicine Publications

The therapeutic application of microRNA(s) in the field of cancer has generated significant attention in research. Previous studies have shown that miR-205 negatively regulates prostate cancer cell proliferation, metastasis, and drug resistance. However, the delivery of miR-205 is an unmet clinical need. Thus, the development of a viable nanoparticle platform to deliver miR-205 is highly sought. A novel magnetic nanoparticle (MNP)-based nanoplatform composed of an iron oxide core with poly(ethyleneimine)-poly(ethylene glycol) layer(s) was developed. An optimized nanoplatform composition was confirmed by examining the binding profiles of MNPs with miR-205 using agarose gel and fluorescence methods. The novel formulation was applied …

Characterisation Of The Structure And Oligomerisation Of Islet Amyloid Polypeptides (Iapp): A Review Of Molecular Dynamics Simulation Studies, Sandra J Moore, Krushna Sonar, Prashant Bharadwaj, Evelyne Deplazes, Ricardo L Mancera

Research outputs 2014 to 2021

Human islet amyloid polypeptide (hIAPP) is a naturally occurring, intrinsically disordered protein whose abnormal aggregation into amyloid fibrils is a pathological feature in type 2 diabetes, and its cross-aggregation with amyloid beta has been linked to an increased risk of Alzheimer's disease. The soluble, oligomeric forms of hIAPP are the most toxic to β-cells in the pancreas. However, the structure of these oligomeric forms is difficult to characterise because of their intrinsic disorder and their tendency to rapidly aggregate into insoluble fibrils. Experimental studies of hIAPP have generally used non-physiological conditions to prevent aggregation, and they have been unable to …

Chronically Implanted Intracranial Electrodes: Tissue Reaction And Electrical Changes., Andrew Campbell, Chengyuan Wu

Department of Neurosurgery Faculty Papers

The brain-electrode interface is arguably one of the most important areas of study in neuroscience today. A stronger foundation in this topic will allow us to probe the architecture of the brain in unprecedented functional detail and augment our ability to intervene in disease states. Over many years, significant progress has been made in this field, but some obstacles have remained elusive-notably preventing glial encapsulation and electrode degradation. In this review, we discuss the tissue response to electrode implantation on acute and chronic timescales, the electrical changes that occur in electrode systems over time, and strategies that are being investigated …

The "Lightning Bolt" Sign On Computed Tomography During Percutaneous Renal Mass Cryoablation, Qian Yu, Driss Raissi

Radiology Faculty Publications

Ice‑ball fracture is a rare and often overlooked entity that may lead to intraprocedural hemorrhage after percutaneous cryoablation of renal masses. There is scant literature on ice‑ball fractures associated with percutaneous renal cryoablation. Immediate recognition of the lightning bolt sign during intraprocedural computed tomography can help identify patients who may have developed this complication.

Camilla “Millie” Herrera, Csusb

South Colton Oral History Project Collection

No abstract provided.

Interaction Between The Microbiome And Tp53 In Human Lung Cancer., K Leigh Greathouse, James R White, Ashely J Vargas, Valery V Bliskovsky, Jessica A Beck, Natalia Von Muhlinen, Eric C Polley, Elise D Bowman, Mohammed A Khan, Ana I Robles, Tomer Cooks, Bríd M Ryan, Noah Padgett, Amiran H Dzutsev, Giorgio Trinchieri, Marbin A Pineda, Sven Bilke, Paul S Meltzer, Alexis N Hokenstad, Tricia M Stickrod, Marina R Walther-Antonio, Joshua P Earl, Joshua C Mell, Jaroslaw E Krol, Sergey V Balashov, Archana S Bhat, Garth D Ehrlich, Alex Valm, Clayton Deming, Sean Conlan, Julia Oh, Julie A Segre, Curtis C Harris

Faculty Research 2018

BACKGROUND: Lung cancer is the leading cancer diagnosis worldwide and the number one cause of cancer deaths. Exposure to cigarette smoke, the primary risk factor in lung cancer, reduces epithelial barrier integrity and increases susceptibility to infections. Herein, we hypothesize that somatic mutations together with cigarette smoke generate a dysbiotic microbiota that is associated with lung carcinogenesis. Using lung tissue from 33 controls and 143 cancer cases, we conduct 16S ribosomal RNA (rRNA) bacterial gene sequencing, with RNA-sequencing data from lung cancer cases in The Cancer Genome Atlas serving as the validation cohort.

RESULTS: Overall, we demonstrate a lower alpha …

A Robust Pax7egfp Mouse That Enables The Visualization Of Dynamic Behaviors Of Muscle Stem Cells., Elisia D Tichy, David K Sidibe, Christopher D Greer, Nicholas M Oyster, Panteleimon Rompolas, Nadia Rosenthal, Helen M Blau, Foteini Mourkioti

Faculty Research 2018

BACKGROUND: Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regeneration. In the majority of regeneration studies, MuSCs are isolated by fluorescence-activated sorting (FACS), based on cell surface markers. It is known that MuSCs are a heterogeneous population and only a small percentage of isolated cells are true stem cells that are able to self-renew. A strong Pax7 reporter line would be valuable to study the in vivo behavior of Pax7-expressing stem cells.

METHODS: We generated and characterized …

2018 Ursinus College Academic Convocation Program, Ursinus College

Academic Convocation Programs

This Ursinus College Academic Convocation program lists speakers and events for the opening of the 2018 academic year.

Biodesign Program, Edna W. Lawrence Nature Lab, Risd Co-Works, Campus Exhibitions

Biodesign: From Inspiration to Integration

Program created on the occasion of Biodesign: From Inspiration to Integration, August 24, 2018, an exhibition opening and symposium organized as part of RISD Nature Lab’s 80th anniversary celebrations at the Woods-Gerry Gallery, Providence, Rhode Island.

Role Of Intrinsic Disorder In Animal Desiccation Tolerance, Brett Janis, Clinton Belott, Michael Menze

Faculty and Staff Scholarship

This review compares the molecular strategies employed by anhydrobiotic invertebrates to survive extreme water stress. Intrinsically disordered proteins (IDPs) play a central role in desiccation tolerance in all species investigated. Various hypotheses about the functions of anhydrobiosisrelated intrinsically disordered (ARID) proteins, including late embryogenesis abundant (LEA) and tardigrade-specific intrinsically disordered proteins, were evaluated by broad sequence characterization. A surprisingly wide range in sequence characteristics including hydropathy and the frequency and distribution of charges was discovered. Interestingly, two clusters of similar proteins were found that potentially correlate with distinct functions. This may indicate two broad groups of ARID proteins, composed of …

Low Peripheral T Follicular Helper Cells In Perinatally Hiv-Infected Children Correlate With Advancing Hiv Disease., Bret Mccarty, Mussa Mwamzuka, Fatma Marshed, Matthew Generoso, Patricia Alvarez, Tiina Ilmet, Adam Kravietz, Aabid Ahmed, William Borkowsky, Derya Unutmaz, Alka Khaitan

Faculty Research 2018

Background: T follicular helper (Tfh) cells are crucial for B cell differentiation and antigen-specific antibody production. Dysregulation of Tfh-mediated B cell help weakens B cell responses in HIV infection. Moreover, Tfh cells in the lymph node and peripheral blood comprise a significant portion of the latent HIV reservoir. There is limited data on the effects of perinatal HIV infection on Tfh cells in children. We examined peripheral Tfh (pTfh) cell frequencies and phenotype in HIV-infected children and their associations with disease progression, immune activation, and B cell differentiation.

Methods: In a Kenyan cohort of 76 perinatally HIV-infected children, comprised of …

In Vivo, Real-Time Spectroscopic Assessment Of Contusion-Based Spinal Cord Injury In A Rat Model, Kyle Kelly Bishop

Theses - ALL

The goal of this study was to (1) develop a methodology for real-time, in vivo probing of chemical and physical changes in spinal cords and (2) compare these changes in the immediate aftermath of a localized contusive injury to uninjured spinal cords. Raman spectroscopy images were obtained on in vivo spinal cords that had been surgically exposed between T9 and T10. A total of six rats were studied in two n=3 groups of injured and uninjured control animals. A single 830 nm laser of 100 um round spot size was either spatially scanned across the cord or held at a …