Digital Commons Network^™

Using Cogenerative Dialogue To Catalyse Change, Carol A. Woodburn-Mcdonald

Dissertations, Theses, and Capstone Projects

Cogenerative dialogue is an empowering pedagogical approach to advance research. In my study cogenerative dialogue and coteaching were employed in an algebra 1 class in an urban high school in New York City. Lessons were cotaught with students and were videotaped for further analysis. The findings suggest that cogens constitute an excellent avenue to catalyze change in an urban algebra class.

Gender And Terrorism: A Homeland Security Perspective, Diana Rosa Rodriguez-Spahia

Dissertations, Theses, and Capstone Projects

While scholars have been studying the growing trend of female terrorists for several years, their research has not permeated politics or the media to help inform our Homeland Security policies. The findings from this body of research indicate that there is hesitance on behalf of the public (especially politicians and law enforcement) to acknowledge that women can be terrorists due to deeply engrained gender norms and expectations about gender roles. Terrorist groups are exploiting this unwillingness by recruiting more women to perpetrate terrorist acts (Lele, 2014; Bloom, 2011). Against the backdrop of the changes in gender norms and expectations that …

The Body And The Sacred In Contemporary Italian Women Writers, Laura R Feola

Dissertations, Theses, and Capstone Projects

My dissertation explores the presence of what has been called the “persistence of the sacred” in modern and contemporary Western culture. More specifically, I focus on the intertwining dimensions of the human body and the experience of the sacred in selected works by Dacia Maraini, Elena Ferrante, Cristina Campo, and Alda Merini. Despite their different voices, and the “secular” or “religious” labels with which each of these Italian authors could be defined or confined, I identify and analyze patterns, similarities, and differences in the interwoven realities of the body and the sacred present in their works.[1]

[1] See Snyder, …

Early Term Effects Of Rhbmp-2 On Pedicle Screw Fixation In A Sheep Model: Histomorphometric And Biomechanical Analyses, Jeffrey M. Toth, Mei Wang, Chetan Patel, Akshi Arora

Biomedical Engineering Faculty Research and Publications

Background: The effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) on pedicle screw pullout force and its potential to improve spinal fixation have not previously been investigated. rhBMP-2 on an absorbable collagen sponge (ACS) carrier was delivered in and around cannulated and fenestrated pedicle screws in a sheep lumbar spine instability model. Two control groups (empty screw and ACS with buffer) were also evaluated. We hypothesized that rhBMP-2 could stimulate bone growth in and around the cannulated and fenestrated pedicle screws to improve early bone purchase.

Methods: Eight skeletally mature sheep underwent destabilizing laminectomies at L2–L3 and L4–L5 followed by …

Knowledge, Perception And Practice Towards Oxytocin Stability And Quality: A Qualitative Study Of Stakeholders In Three Resource-Limited Countries, Victoria L. Oliver, Peter A. Lambert, Kyu Kyu Than, Yasmin Mohamed, Stanley Luchters, Snigdha Verma, Ranjana Yadav, Vishwajeet Kumar, Alula M. Teklu, Moti Tolera, Abebaw Minaye, Michelle P. Mcintosh

Population Health, East Africa

Background: Oxytocin is the gold standard drug for the prevention of postpartum haemorrhage, but limitations in cold chain systems in resource-constrained settings can severely compromise the quality of oxytocin product available in these environments. This study investigated the perspectives and practices of stakeholders in low and lower-middle income countries towards oxytocin, its storage requirements and associated barriers, and the quality of product available.

Methods: Qualitative inquiries were undertaken in Ethiopia, India and Myanmar, where data was collected through Focus Group Discussions (FGDs) and In-Depth Interviews (IDIs). A total of 12 FGDs and 106 IDIs were conducted with 158 healthcare providers …

Issue 17

The Synapse: Intercollegiate science magazine

No abstract provided.

Status Update On The Threat Of Babesiosis Returning To The United States, Jason Tidwell, Christopher Vitek, Donald B. Thomas, John M. Thomas

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Babesiosis is a hemolytic disease caused by protozoan parasites in the genus Babesia, transmitted through the saliva of infected ticks. The most economically important species, Babesia bigemina and B. bovis, infect cattle and are the etiological agents of bovine babesiosis. In the southern United States, eradication efforts directed against the tick vectors, Boophilus spp., began in the early 1900s. A quarantine zone in south Texas along the US/Mexico border was subsequently established following the eradication of the disease in the US. The permanent quarantine zone, spanning approximately 33% of the total shared border between Texas and Mexico, has helped limit …

Design Of Efficient Hybrid E/F Power Amplifier For Biomedical Purposes, Saad Mutashar

Iraqi Journal of Computers, Communications, Control and Systems Engineering

This paper introduces a new hybrid E/F power amplifier for subcutaneous applications. The proposed design is based on Amplitude Shift Keying (ASK) modulation technique with Industrial Scientific Medical (ISM) band operating at 135 kHz to avoid the tIssue damage. The Hybrid E/F power amplifier combines the tuning network circuits and uses a control unit to control a selectable switch to choose the desired amplifier. The Amplitude Shift Keying modulator is proposed to supply the proposed hybrid amplifier with approximately constant DC Voltage. The proposed power amplifier aims to provide an appropriate power to power the implantable devices and reduce the …

A Visionary Organization: From Donor Intent To New Horizons Of Race And Gender Equity, Carolyn Chernoff, V Varun Chaudhry

The Foundation Review

This article documents the unique trajectory of the Leeway Foundation and its transition from sole-director family foundation to an independent foundation. Over 25 years, Leeway shifted in structure and grantmaking, yet has remained in line with its founder’s original mission: to fund women artists in the Philadelphia region.

This article focuses on the shift from the founder’s initial intentions to what is now an organization informed by models of racial and gender equity, funding women, trans, and gender nonconforming artists working for social change. Leeway thus serves as a case study for examining transformational shifts in mission, vision, and constituency …

The Relationship Between Psychotherapist Personality And Therapeutic Alliance, Michael Finlay

Loma Linda University Electronic Theses, Dissertations & Projects

Time-limited effective psychotherapy is a topic that is frequently addressed in clinical therapy research. Though a wide range of therapeutic factors, expectancy effects, techniques, and extratherapeutic have all been demonstrated to be related to outcome, researchers have consistently identified the therapeutic alliance as one of the strongest factors in predicting psychotherapy outcomes. Researchers are beginning to measure the effectiveness of therapy by evaluating improvements in outcome measures, and client reported therapeutic alliance. Researchers have recently began investigating the common personality profiles among psychotherapists, and have hypothesized that there is a relationship between psychotherapist personality and therapeutic alliance. The goal of …

Parental Hormones Are Associated With Crop Loss And Family Sickness Following Catastrophic Flooding In Lowland Bolivia, Benjamin C. Trumble, Jonathan Stieglitz, Adrian Jaeggi, Bret Beheim, Matthew Schwartz, Edmond Seabright, Daniel Cummings, Hillard Kaplan, Michael Gurven

ESI Publications

The physiology of fatherhood is a growing field of study, and variability in hormonal mediators of reproductive effort (e.g. testosterone, cortisol) can predict variability in paternal investment. Studies often find that lower testosterone levels are associated with increased paternal investment, though most studies are conducted under relatively stable ecological conditions. In this paper, we examine parental physiological correlates of crop loss and family health problems among Tsimane forager-horticulturalists following a catastrophic flood in lowland Bolivia. Immediately after a devastating 2014 flood that impacted >75% of Tsimane communities, we conducted structured interviews examining crop losses and morbidity, and collected saliva specimens …

Sex Differences In Rhesus Monkeys’ Digit Ratio (2d:4d Ratio) And Its Association With Maternal Social Dominance Rank, Alexander Baxter, Elizabeth K. Wood, Parker Jarman, Ashley N. Cameron, John P. Capitanio, James Dee Higley

Faculty Publications

Prenatal androgen exposure (PAE) plays a pivotal role in masculinizing the developing body and brain, and extreme exposure may contribute to autism, anxiety disorder and schizophrenia. One commonly used biomarker for PAE is the pointer-to-ring-finger digit length (2D:4D) ratio. Although this biomarker is widely used in human studies, relatively few studies have investigated 2D:4D ratio in nonhuman primates, particularly rhesus macaques (Macaca mulatta), one of the most commonly used animals in biomedical research. Thus far, data suggest that sexual dimorphism in 2D:4D ratio may be in the opposite direction in some monkey species, when compared to the pattern …

A Spatio-Temporal Model Reveals Self-Limiting Fcɛri Cross-Linking By Multivalent Antigens, Md Shahinuzzaman, Jawahar Khetan, Dipak Barua

Chemical and Biochemical Engineering Faculty Research & Creative Works

Aggregation of cell surface receptor proteins by multivalent antigens is an essential early step for immune cell signalling. A number of experimental and modelling studies in the past have investigated multivalent ligand-mediated aggregation of IgE receptors (FcɛRI) in the plasma membrane of mast cells. However, understanding of the mechanisms of FcɛRI aggregation remains incomplete. Experimental reports indicate that FcɛRI forms relatively small and finite-sized clusters when stimulated by a multivalent ligand. By contrast, modelling studies have shown that receptor cross-linking by a trivalent ligand may lead to the formation of large receptor superaggregates that …

Propofol Inhibits Prokaryotic Voltage-Gated Na+ Channels By Promoting Activation-Coupled Inactivation, Elaine Yang, Daniele Granata, Roderic G. Eckenhoff, Vincenzo Carnevale, Manuel Covarrubias

Department of Neuroscience Faculty Papers

Propofol is widely used in the clinic for the induction and maintenance of general anesthesia. As with most general anesthetics, however, our understanding of its mechanism of action remains incomplete. Local and general anesthetics largely inhibit voltage-gated Na⁺ channels (Navs) by inducing an apparent stabilization of the inactivated state, associated in some instances with pore block. To determine the biophysical and molecular basis of propofol action in Navs, we investigated NaChBac and NavMs, two prokaryotic Navs with distinct voltage dependencies and gating kinetics, by whole-cell patch clamp electrophysiology in the absence and presence of propofol at clinically relevant concentrations …

Relationship Between Mineralogy And Minor Element Partitioning In Limpets From An Ischia Co 2 Vent Site Provides New Insights Into Their Biomineralization Pathway, Gerald Langer, Aleksey Sadekov, Gernot Nehrke, Cecilia Baggini, Riccardo Rodolfo-Metalpa, Jason M. Hall-Spencer, Emilio Cuoco, Jelle Bijma, Henry Elderfield

School of Biological and Marine Sciences

No abstract provided.

A Coastal Vulnerability Assessment For Planning Climate Resilient Infrastructure, Jennifer M. Brown, Karyn Morrissey, Philip Knight, Thomas D. Prime, Luis Pedro Almeida, Gerd Masselink, Cai O. Bird, Douglas Dodds, Andrew J. Plater

School of Biological and Marine Sciences

No abstract provided.

Ultrastructural Changes In Peripheral Blood Leukocytes In Α-Synuclein Knockout Mice, Hammad Tashkandi, Afshin Shameli, Clifford V. Harding, Robert W. Maitta

Faculty Scholarship

Effects of α-synuclein deficiency on cellular blood components have not been extensively investigated. This study evaluated ultrastructural changes of leukocytes in α-synuclein knockout (KO) mice using electron microscopy (EM). The following ultrastructural characteristics were quantified in leukocytes: mitochondria, primary granules, specific granules (SG), Golgi apparatus (GA), inclusions, rough-endoplasmic reticulum (RER), smooth-endoplasmic reticulum (SER), and cellular projections (CP). EM showed increased numbers or amounts of SG, inclusions, and SER in KO group (5.3 ± 4.5 in WT vs. 14.1 ± 10.3 in KO, p = 0.02; 0.4 ± 0.9 in WT vs. 3.2 ± 2.8 in KO, p = 0.007; and …

2018 September, Morehead State University. Office Of Communications And Marketing

Morehead State Press Release Archive, 1961 to the Present

Press releases for September of 2018.

Differential 5-Year Brain Atrophy Rates In Cognitively Declining And Stable Apoe-Ε4 Elders, Dana A. Kelly, Michael Seidenberg, Katherine Reiter, Kristy A. Nielson, John L. Woodard, J. Carson Smith, Sally Durgerian, Stephen M. Rao

Psychology Faculty Research and Publications

Objective: The apolipoprotein E (APOE) ε4 allele is the most important genetic risk factor for late-onset Alzheimer’s disease. Many ε4 carriers, however, never develop Alzheimer’s disease. The purpose of this study is to characterize the variability in phenotypic expression of the ε4 allele, as measured by the longitudinal trajectory of cognitive test scores and MRI brain volumes, in cognitively intact elders. Method: Healthy older adults, ages 65–85, participated in a 5-year longitudinal study that included structural MRI and cognitive testing administered at baseline and at 1.5 and 5 years postenrollment. Participants included 22 ε4 noncarriers, 15 ε4 carriers who experienced …

Georgia Southern Magazine, Georgia Southern University

Georgia Southern Magazine

• News and Events
• Introducing the Parker College of Business
• Meet the Interim President
• What 'Right' Looks Like
• From Savannah to Hollywood and Back
• Finding Fulfillment
• Something to Believe In
• 40 Under 40

Maternal Predictors Of Intrauterine Growth Retardation, Nadia Mohammad, Arjumand Sohaila, Unaib Rabbani, Sufian Ahmed, Shakeel Ahmed, Syed Rehan Ali

Department of Paediatrics and Child Health

Objective: To identify maternal factors associated with intrauterine growth restriction (IUGR).
Study Design: A case-control study.
Place and Duration of Study: Neonatal Unit of The Aga Khan Hospital for Women (AKHW), Karimabad, from January 2014 to December 2015.
Methodology: Cases were IUGR live born babies (n=90), while control were appropriate-for-gestational age (AGA) babies (n=180). Information recorded in pre-designed proforma included gestational age and birth weight of baby, demographics of mothers, pregnancy related medical and obstetric complications. Data were analysed through SPSS-19. Multivariable logistic regression was used to determine the maternal factors associated with the intrauterine growth restriction.
Results: Maternal factors …

Pathophysiology Of Environmental Enteric Dysfunction And Its Impact On Oral Vaccine Efficacy, Chelsea Marie, Syed Asad Ali, Kanta Chandwe, William Petri Jr A, Paul Kelly

Department of Paediatrics and Child Health

Environmental enteric dysfunction (EED) refers to a subclinical disorder of intestinal function common in tropical countries and in settings of poverty and economic disadvantage. The enteropathy that underlies this syndrome is characterized by mucosal inflammation and villus blunting mediated by T cell activation. Epithelial cell disruption and microbial translocation drive systemic inflammation. EED in young children is associated geographically with growth failure, malnutrition, and greatly impaired responses to oral vaccines, notably rotavirus and poliovirus vaccines. In this review, we describe the pathophysiology of EED and examine the evidence linking EED and oral vaccine failure. This evidence is far from conclusive. …

Bleeding Women Dry: Tampon Taxes And Menstrual Inequity, Jorene Ooi

Northwestern University Law Review

In recent years, the problem of menstrual inequity has attracted increased attention. Most states impose a sales tax on menstrual hygiene products—a “tampon tax.” A burgeoning social movement has sought to end the tampon tax, and lawmakers have taken notice by introducing, and in some cases successfully passing, measures to repeal the tax by exempting menstrual hygiene products from the sales tax. This Note evaluates, from a tax policy standpoint, the pros and cons of repealing the tampon tax. It argues that although repeal is usually undesirable as a matter of tax design, the tax should nevertheless be repealed both …

Anxiety Modulates The Relation Between Attention-Deficit/Hyperactivity Disorder Severity And Working Memory-Related Brain Activity, Dennis Van Der Meer, Pieter J. Hoekstra, Daan Van Rooij, Anderson M. Winkler, Hanneke Van Ewijk, Dirk J. Heslenfeld, Jaap Oosterlaan, Stephen V. Faraone, Barbara Franke, Jan K. Buitelaar

School of Medicine Publications

OBJECTIVES: Individuals with attention-deficit/hyperactivity disorder (ADHD) often have heightened levels of anxiety, which has been associated with worse performance on working memory tasks. Knowledge of the neural pathways underlying the combined presence of ADHD and anxiety may aid in a better understanding of their co-occurrence. Therefore, we investigated how anxiety modulates the effect of ADHD severity on neural activity during a visuospatial working memory (VSWM) task.

METHODS: Neuroimaging data were available for 371 adolescents and young adults participating in the multicentre cohort study NeuroIMAGE (average age 17.1 years). We analysed the effects of ADHD severity, anxiety severity and their …

Protein Tyrosine Phosphatases As Potential Regulators Of Stat3 Signaling, Mihwa Kim, Liza D. Morales, Ik-Soon Jang, Yong-Yeon Cho, Dae Joon Kim

School of Medicine Publications

The signal transducer and activator of transcription 3 (STAT3) protein is a major transcription factor involved in many cellular processes, such as cell growth and proliferation, differentiation, migration, and cell death or cell apoptosis. It is activated in response to a variety of extracellular stimuli including cytokines and growth factors. The aberrant activation of STAT3 contributes to several human diseases, particularly cancer. Consequently, STAT3-mediated signaling continues to be extensively studied in order to identify potential targets for the development of new and more effective clinical therapeutics. STAT3 activation can be regulated, either positively or negatively, by different posttranslational mechanisms including …

Ensuring Adequate Vitamin D Intake Among Infants And Children, Alicia Kunzler, Mateja R. Savoie-Roskos, Carrie Durward

All Current Publications

This fact sheet explains what vitamin D does, why a child might need more vitamin D, and three ways to increase levels of vitamin D in the body: through diet, sunlight, and supplementation.

Advancing Social Connection As A Public Health Priority In The United States, Julianne Holt-Lunstad, Theodore Robles, David A. Sbarra

Faculty Publications

A robust body of scientific evidence indicates that being embedded in high-quality close relationships and feeling socially connected to the people in your life is associated with decreased risk for all-cause mortality as well as a range of disease morbidities. Despite mounting evidence that the magnitude of these associations is comparable to many leading health determinants (that receive significant public health resources), government agencies, healthcare providers and associations, and public/private healthcare funders are slow to recognize human social relationships as either a health determinant or health risk marker in a manner that is comparable to other public health priorities. This …

Proposal For A Tiered Dietary Bioaccumulation Testing Strategy For Engineered Nanomaterials Using Fish, Rd Handy, J Ahtiainen, Navas J Maria, G Goss, Eaj Bleeker, Der Kammer F Von

School of Biological and Marine Sciences

No abstract provided.

Icis 2017 Panel Report: Break Your Shackles! Emancipating Information Systems From The Tyranny Of Peer Review, Cecil Eng Huang Chua, Jason Bennett Thatcher, Fred Niederman, Yolande E. Chan, Elizabeth J. Davidson

Business and Information Technology Faculty Research & Creative Works

The paper presents the report of a panel that debated the review process in the information systems (IS) discipline at ICIS 2017 in Seoul, Korea. The panel asked the fundamental question of whether we need to rethink the way we review papers in the discipline. The panelists partnered with the audience to explore some reviewing limitations in IS today and the ways that reviewing in the discipline might change to address some of its difficulties. We first report key concerns with modern reviewing. We then present arguments for and against three proposals (i.e., paying for reviews, mandatory reviews, and open …

Modeling Methylation Data As An Additional Genetic Variance Component, Marcio Almeida, Juan M. Peralta, Jose Garcia, Vincent P. Diego, Harald H. H. Goring, Sarah Williams-Blangero, John Blangero

School of Medicine Publications

High-throughput platforms allow the characterization of thousands of previously known methylation sites. These platforms have great potential for investigating the epigenetic effects that are partially responsible for gene expression control. Methylation sites provide a bridge for the investigation of real-time environmental contributions on genomic events by the alteration of methylation status of those sites. Using the data provided by GAW20’s organization committee, we calculated the heritability estimates of each cytosine-phosphate-guanine (CpG) island before and after the use of fenofibrate, a lipid-control drug. Surprisingly, we detected substantially high heritability estimates before drug usage. This somewhat unexpected high sample correlation was corrected …