Digital Commons Network^™

The Aba Guidelines: The Arizona Experience, Larry Hammond, Robin M. Maher

Hofstra Law Review

No abstract provided.

Balancing National Security Interests Against The Value Of Chinese Capital, Brendan Catalano

Hofstra Law Review

No abstract provided.

Agricultural Contamination Impacts Antibiotic Resistance Gene Abundances In River Bed Sediment Temporally, Rachelle E. Beattie, Michael P. Walsh, Mercedes Cecilia Cruz, L. Rex Mcaliley, Laurel Dodgen, Wei Zheng, Krassimira R. Hristova

Biological Sciences Faculty Research and Publications

Kewaunee County, Wisconsin is an agricultural area dominated by concentrated animal feeding operations and manure fertilized cropland. The objective of this study was to characterize chemical and antibiotic resistance gene (ARG) profiles of 20 surface water locations in Kewaunee County to better understand relationships between agricultural contamination and ARG abundance over one year. Surface water (n = 101) and bed sediment (n = 93) were collected from 20 sites during five timepoints between July 2016 and May 2017. Samples were analyzed for six genes (erm(B), tet(W), sul1, qnrA, intI1 and 16S rRNA) and water chemistry …

The Syndrome Of Romantic Love, Arina Pismenny

Dissertations, Theses, and Capstone Projects

What kind of phenomenon is romantic love? Many philosophers, psychologists, and ordinary folk think it is an emotion. I challenge this assumption and argue instead that romantic love is best characterized as a syndrome ⎼ a pattern comprised of different kinds of mental states and behaviors that tend to co-occur. An examination of major emotion theories in philosophy and psychology demonstrates that romantic love does not fit into any of them. Likewise, the commonly endorsed but increasingly controversial categories of basic and nonbasic emotions do not account for romantic love. While both culture and evolution have shaped the phenomenon of …

Regulation Of Dissolved Arsenic Using Zero-Valent Iron With Gypsum And Sulfate Reducing Bacteria: Laboratory Microcosm And Column Studies, Ying Liu

Dissertations, Theses, and Capstone Projects

Bench scale microcosm incubation was first conducted in two stages to examine the removal of arsenic (As) by zero-valent iron (ZVI) in the presence of sulfate reducing bacteria, gypsum as well as organic substrates under anaerobic condition. About 98% of dissolved As was removed from solution within 20 days with concurrent decrease of dissolved sulfate and growth of bacterial population. Mineralogy analysis using SEM-EDS found the formation of iron sulfide and Fourier-transformed infrared (FTIR) spectroscopy analysis indicates that some As is associated with pyrite. The main iron corrosion product was found as ferrihydrite with traces of lepidocrocite. Sequential leaching shows …

Chile’S Decree-Law 1094: A Source Of Immigrant Vulnerability, Joao M. Da Silva

Dissertations, Theses, and Capstone Projects

The South American nation of Chile is rapidly becoming a receiving nation for immigrants from other South American nations and the Caribbean. By December 31, 2017, the immigrant population had surpassed 1.1 million, 300,000 of whom are in irregular status. Immigration to Chile is governed by Decree-Law No. 1094 (DL 1094) of 1975, the oldest immigration law in South America, decreed by the military junta led by General Augusto Pinochet. I argue that the continued application of DL 1094, and the Chilean state’s failure to enact a new law that addresses immigration from a human rights-based approach, contributes to perpetuating …

Impacts Of Climate Extremes On Terrestrial Productivity, Suhua Wei

Dissertations, Theses, and Capstone Projects

Terrestrial biosphere absorbs approximately 28% of anthropogenic CO₂ emissions. This terrestrial carbon sink might become saturated in a future climate regime. To explore the issues associated with this topic, an accurate estimate of gross primary production (GPP) of global terrestrial ecosystems is needed. A major uncertainty in modeling global terrestrial GPP is the parameter of light use efficiency (LUE). Most LUE estimates in global models are satellite-based and coarsely measured with emphasis on environmental variables. Others are from eddy covariance towers with much greater spatial and temporal data quality and emphasis on mechanistic processes, but in a limited number …

Synthesis And Characterization Of Cytocompatible Sponge-Mimetic Scaffolds And Biomedical Polymers, Kamia Punia

Dissertations, Theses, and Capstone Projects

This dissertation describes the novel synthetic methodologies towards: a) protein/polysaccharide intercalated sponge-mimetic scaffolds for 3D cell culture, b) peptide-mimetic cationic amphiphilic antibacterial polymers, and c) bioactive Poly(DL-lactide-co-glycolide) (PLGA) nanofibers by solution blow spinning for the treatment of cancer and traumatic wound care.

The classic “chemical garden” experiment is reconstructed to produce protein/polysaccharide (ingredients of cyanobacterial origin) intercalated silicate-phosphate tubules that resemble tubular sponges. The constructs were synthesized by seeding calcium chloride into a solution of sodium silicate-potassium phosphate and gelatin/polysaccharides. The morphology and composition of sponge-mimetic tubules were analyzed by a battery of techniques. Bioconjugation and coating protocols were developed …

Examining The Impact Of Study Abroad For Community College Students: Five Case Studies, Kathryn B. Wilson

Dissertations, Theses, and Capstone Projects

There is general agreement that positive student learning outcomes are associated with participation in study abroad. The aim of this paper is to explore how participation in study abroad by community college students impacts their global learning. While studies about the impact of study abroad are plentiful for senior colleges, research about community college students’ experiences is lacking. Furthermore, while studies about how study abroad impacts language acquisition or cultural awareness are common, there is a need for more research about the impact of study abroad programs on global self-awareness. Additionally, this paper explores how students who are ‘emerging adults’ …

Recognizing The Twentieth-Century Love Story, Angela Francis

Dissertations, Theses, and Capstone Projects

Recognizing the Twentieth-Century Love Story investigates an alternative framework through which we can understand the form and function of love stories in the twentieth century. While the love story has previously been understood in terms of a requirement that the lover renunciate passion in order to enjoy a positive narrative outcome, I suggest that some love narratives instead center mutual and “accurate-enough” recognition as a requirement of the desired happily ever after. In addition to requiring that the characters “know themselves,” such recognition goes beyond framing the loved other as an independent subject by also recognizing the beloved in ways …

List, Sample, And Count, Ali Assarpour

Dissertations, Theses, and Capstone Projects

Counting plays a fundamental role in many scientific fields including chemistry, physics, mathematics, and computer science. There are two approaches for counting, the first relies on analytical tools to drive closed form expression, while the second takes advantage of the combinatorial nature of the problem to construct an algorithm whose output is the number of structures. There are many algorithmic techniques for counting, they cover the explicit approach of counting by listing to the approximate approach of counting by sampling.

This thesis looks at counting three sets of objects. First, we consider a subclass of boolean functions that are monotone. …

Unarticulated Constituents And Theories Of Meaning, Jesse Rappaport

Dissertations, Theses, and Capstone Projects

This work is an investigation into a phenomenon introduced by John Perry that I call ‘totally unarticulated constituents.’ These are entities that are part of the propositional content of a speech act, but are not represented by any part of the sentence uttered or of the thought that is being expressed - that is, they are fully unarticulated. After offering a novel definition of this phenomenon, I argue that totally unarticulated constituents are attested in natural language, and may in fact be quite common. This raises fatal problems for a prominent theory of underspecification defended by Jason Stanley, according to …

A Narrative Approach To Investigating The Contextual Nature Of Adolescent Self-Regulation, Kelly Conover

Dissertations, Theses, and Capstone Projects

Self-regulation has been identified as important for academic achievement, positive mental health, and social success (Steinberg, 2014, Mischel, 2014). This inquiry begins with self-regulation defined traditionally as “modulation of thoughts, emotions and behaviors working in conjunction, with deliberate or automated use of specific mechanisms and skills" (Karoly, 1993, pg. 25) and extends beyond that and similar definitions to a definition that adds “as enacted in relationships and situations with culturally-relevant media.” The need for such an expansion urgently accounts for the fact that young people are living in high-risk settings, where trauma, violence and economic difficulty are implicated not only …

Synthesis And Evaluation Of Densely-Functionalized Troponoids, Danielle R. Hirsch

Dissertations, Theses, and Capstone Projects

Herein, we document our efforts to expand the scope of troponoid synthetic methodology towards densely-substituted scaffolds. This body of work has focused primarily on an oxidopyrylium cycloaddition/ring-opening strategy for the synthesis and biochemical evaluation of troponoids for assistance in a variety of medicinal chemistry studies. In Chapter 1, we outline the use of this synthetic strategy in the profiling of a library of synthetic αHTs against an aminoglycoside antibiotic resistance enzyme known as aminoglycoside-2’’-O-nucleotidyltransferase [ANT(2’’)-Ia]. Enzymatic mechanistic insights have been gleaned from an assessment of troponoid/antibiotic synergistic potential. In particular, two synthetic constructs were identified as promising antibiotic adjuvant candidates, …

Can Mindfulness Training Reduce Stress Reactivity In First-Year College Students?, Liat Zitron

Dissertations, Theses, and Capstone Projects

ABSTRACT

Can Mindfulness Training Reduce Stress-Reactivity in First-Year College Students?

By

Liat Zitron

Advisor: Yu Gao, PhD

The positive effects of mindfulness-based practices on stress reactivity have been gaining steady attention in recent years. Yet, the effects of mindfulness training on stress responses via the autonomic nervous system (ANS) functioning, and in particular, changes in cardiovascular activity, have rarely been researched. The polyvagal theory (Porges, 1995) offers a theoretical framework in which the roles of the subdivisions of the ANS in regulating emotion and behaviors are delineated, and closely connected to the concept of heart rate variability (HRV) and its …

Influence Of The Silk Road Trade On The Craniofacial Morphology Of Populations In Central Asia, Ayesha Yasmeen Hinedi

Dissertations, Theses, and Capstone Projects

Large-scale human migrations over long periods of time are known to affect population composition. In the second century B.C the demand for silk threads in the West opened trade opportunities between China and the Europe. This allowed for new pathways to be established and old ones reinforced across the vast region of Central Asia; a network of overland and sea routes linking East with West for sixteen hundred years that became collectively known as the Silk Road. Populations living along these routes were affected by a constant influx of traders, merchants, and invading armies attempting to control the region. Although …

Adults’ Perceptions Of Children With Mental Illness Labels Who Tell Truths And Lies, Jessica Lynn Mccurdy

Dissertations, Theses, and Capstone Projects

This study examined whether children’s truth- and lie-telling is perceived differently by adults when the children have mental illness labels (MIL). Participants (N= 432) read a vignette and watched a video from each of four veracity/motivation (i.e., prosocial truth, antisocial truth, prosocial lie, antisocial lie) and child label (i.e., control, ADHD, depression, asthma) conditions. After each video/vignette combination, participants rated their impressions of and responses towards the child. Participants also completed measures of their implicit and explicit attitudes towards mental illness. The results indicated participants had more negative perceptions of children they rated higher on dangerousness and lower …

Domain-Specific Knowledge Exploration With Ontology Hierarchical Re-Ranking And Adaptive Learning And Extension, Grace G. Zhao

Dissertations, Theses, and Capstone Projects

The goal of this research project is the realization of an artificial intelligence-driven lightweight domain knowledge search framework that returns a domain knowledge structure upon request with highly relevant web resources via a set of domain-centric re-ranking algorithms and adaptive ontology learning models. The re-ranking algorithm, a necessary mechanism to counter-play the heterogeneity and unstructured nature of web data, uses augmented queries and a hierarchical taxonomic structure to get further insight into the initial search results obtained from credited generic search engines. A semantic weight scale is applied to each node in the ontology graph and in turn generates a …

Investigation Of Biogeochemical Mechanisms Of Greenhouse Gas Production In The Urban Hudson River Estuary, Brian Alan Brigham

Dissertations, Theses, and Capstone Projects

Coastal megacities deposit significant amounts of carbon (C), nitrogen (N) and other pollutants into surrounding waters. These inputs, including wastewater and surface water runoff, may affect estuarine and adjacent wetland biogeochemical cycles, microbial production and ultimately greenhouse gas (GHG) efflux. In many megacities pollutant loading is typically greatest after periods of precipitation when the volume of wastewater and storm water runoff exceeds local sanitation capacity, resulting in the discharge of raw sewage into adjacent waters. These combined sewage overflow (CSO) events have received considerable attention primarily due to their potential impact on human health and eutrophication. However, whether these events …

Ulva Spp. Bloom Dynamics In A Hyper-Eutrophic Estuary: Jamaica Bay, New York, Annesia Lamb

Dissertations, Theses, and Capstone Projects

In this dissertation, I present three studies that further our understanding of macroalgae identity, growth, and proliferation. Eutrophication is prevalent in shallow coastal ecosystems world-wide. One of the ecosystem consequences is the development of a bloom forming green marine macroalgae, Ulva spp. Ulva can have negative effects such as Zostera spp. degradation, fish, and shellfish declines. I performed assessments of (1) identity of the bloom-forming Ulva and other macroalgae assemblage, (2) physical, chemical, and biological drivers of Ulva bloom growth and proliferation, and (3) optimal irradiance and temperature requirements for early growth stages in Ulva linza.

The first study …

Increasing Access To Pre-Exposure Prophylaxis (Prep) Among Transgender Women And Trans Feminine Non-Binary Individuals In New York City, Augustus Klein

Dissertations, Theses, and Capstone Projects

In the United States transgender women (i.e., individuals born male whose gender identity is on the feminine spectrum) are a highly vulnerable and marginalized population at high risk for HIV. Substance use, survival sex work, depression, unstable housing, and high levels of victimization and violence are commonly reported by transgender women and trans feminine individuals, indicating the potential for multiple concurrent HIV risks and underlying vulnerabilities. Structural forms of discrimination may contribute to these risk factors, possibly leading to poor outcomes such as unemployment or underemployment, homelessness, and lack of access to gender-affirming health care. Given this context, a biomedical …

Phospholipase D-Dependent Mtorc1 Activation By Glutamine, Elyssa Bernfeld

Dissertations, Theses, and Capstone Projects

Glutamine, the conditionally essential amino acid and most abundant amino acid in human sera, is a key nutrient required for sustaining cell proliferation. Glutamine is essential for nucleotide, protein, and lipid synthesis, all of which are essential for cell proliferation. The mammalian target of rapamycin complex 1 (mTORC1) is a highly conserved protein complex that acts as a sensor of nutrients, relaying signals for the shift from catabolic to anabolic metabolism. While glutamine plays an important role in activating mTORC1, the mechanism is not completely clear. Here we describe a Rag-independent mechanism of mTORC1 activation by glutamine that is dependent …

Characterization And Quantification Of Covalent Modification Of Proteins Using Mass Spectrometry, Pratikkumar N. Rathod

Dissertations, Theses, and Capstone Projects

Identification and characterization of various post-translational modifications of protein is a key to understanding many unknown cellular processes. In the last few decades, mass spectrometry has evolved as an essential and effective analytical tool for qualitative and quantitative analysis of proteins. In this research, we have developed a novel MALDI-MS² based quantification method for Desmosine and Isodesmosine, which served as cross-linking amino acids of elastin, in order to measure the elastin degradation in the body. This is the first quantification method that not only illustrates the potential of MALDI-Ion Trap MS², but also improvement over the current …

Casualties Of Racism: Racial And Ethnic Discrimination And Suicidal Thoughts And Behaviors Among Racial And Ethnic Minority Emerging Adults, Lillian Anais Polanco

Dissertations, Theses, and Capstone Projects

The evidence demonstrating that experiences of racial/ethnic discrimination is detrimental to the mental health of racial/ethnic minority youth is unequivocal. What remains unclear, however, is whether racial/ethnic discrimination increases vulnerability for suicidal thoughts and behaviors in particular, and if so, what are the underlying mechanisms to explain this relation. Drawing upon the Race-based Traumatic Stress Theory (Carter, 2007), which suggests that some individuals may experience racial/ethnic discrimination as a traumatic stressor, and thus, eliciting a traumatic stress response, the present study examined posttraumatic stress reactions (i.e., posttraumatic stress, depression, dissociation, stress sensitivity) as mediators in the relation between racial/ethnic discrimination …

Linking Hostile/Helpless Maternal Representations In Pregnancy And Later Child Protection Involvement: A Pilot Study, Madeleine Terry

Dissertations, Theses, and Capstone Projects

The present pilot study examined whether there are reliable indices in the narratives of pregnant women that can be used to identify child abuse and neglect potential before the birth of the child. The Hostile/Helpless (HH) Classification system (Lyons-Ruth et al., 1995-2005), which detects mental states associated with trauma, disturbances in early attachment, and severe pathology, was adapted for use with the Pregnancy Interview (PI), a semi-structured clinical interview (Slade, 2003) that assesses a woman's emotional experience of pregnancy, and quality of her developing relationship with her baby. The study sample was drawn from a replication study of the Minding …

Demystifying The Placebo Effect, Phoebe Friesen

Dissertations, Theses, and Capstone Projects

This dissertation offers a philosophical analysis of the placebo effect. After offering an overview of recent evidence concerning the phenomenon, I consider several prominent accounts of the placebo effect that have been put forward and argue that none of them are able to adequately account for the diverse instantiations of the phenomenon. I then offer a novel account, which suggests that we ought to think of the placebo effect as encompassing three distinct responses: conditioned placebo responses, cognitive placebo responses, and network placebo responses. Next, I consider implications of the placebo effect’s role in complementary and alternative medicine for discussions …

The Effect Of A Voice Treatment On Facial Expression In Parkinson’S Disease: Clinical And Demographic Predictors, Amanda D. Bono

Dissertations, Theses, and Capstone Projects

Parkinson’s disease (PD) is a neurodegenerative disease associated with a wide range of motoric, cognitive, and behavioral symptoms. Impairments in facial mobility and emotional expressivity are common and can impair communication, in turn, affecting daily functioning and quality of life. Previous research suggests that the Lee Silverman Voice Treatment © (LSVT LOUD; Ramig et al., 2001, 2011) increases vocal loudness and facial expressivity in individuals with PD compared to PD and healthy controls. This study extends the literature by examining the effects of LSVT and an articulation-based control treatment (i.e., ARTIC) on multiple aspects of facial expressivity (i.e., emotional frequency …

The Development Of Novel Platforms For The Imaging Of Cancer By Positron Emission Tomography, Brendon E. Cook

Dissertations, Theses, and Capstone Projects

The role of antibody-based imaging of cancer by positron emission tomography (PET) has expanded significantly in recent years and is poised to radically alter the way that cancer is diagnosed and treated. However, one hurdle that remains is the potentially harmful radiation dose that comes from these imaging agents, as the long circulation time of antibodies (days to weeks) necessitates the use of radionuclides with comparable physical half-lives (i.e. ⁸⁹Zr, ¹²⁴I, etc.). One particularly promising solution is the use of the inverse electron demand Diels-Alder (IEDDA) reaction between a 1,2,4,5-tetrazine (Tz) and a trans-cyclooctene (TCO) for pretargeting. …

Integration Of Bmp And Insulin/Igf-1 Signaling Regulates Multiple Homeostatic Functions In Caenorhabditis Elegans, James F. Clark

Dissertations, Theses, and Capstone Projects

The maintenance of homeostatic functions is key to the survival and well-being of an organism. Regulation of homeostasis relies on varied inputs, both intrinsic and extrinsic, to potentiate a web of interconnected signaling relays. Insulin/IGF-1 signaling (IIS) is a well-known regulator of glucose and lipid metabolism, as well as having far reaching effects in other homeostatic mechanisms. On the other hand, bone morphogenetic protein (BMP), a member of the transforming growth factor beta signaling superfamily, is known for its role in differentiation and development, with only recent studies highlighting potential roles in metabolic homeostasis. Here we elucidate new functions for …

Uneven Policing: Low-Level Arrests During Gentrification, Fiscal Crisis, And Suburbanization, Brenden Beck

Dissertations, Theses, and Capstone Projects

In this dissertation, I analyze trends in low-level policing between 1990 and 2015. I explore how three contextual changes may have shaped policing during this time: gentrification, fiscal crisis, and the suburbanization of poverty and of people of color. I ask four interrelated research questions: How widely did “broken windows” policing, with its emphasis on misdemeanor arrests, diffuse? Do police make more stops and arrests in neighborhoods undergoing gentrification? Do local governments experiencing revenue shortfalls cut their criminal justice functions to save money, or do they increase them to reassert social order? Did the suburbanization of poverty and of people …