Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2018

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 27031 - 27060 of 31359

Full-Text Articles in Entire DC Network

Endocrine And Hematobiochemical Profile Of Lambs Raised In A Semiaridregion With Different Growth Potentials During The Postweaning Period, Shiva Pratap Singh, Gopal Dass, Ramachandran Natesan, Yogender Kushwah, Nandini Sharma, Ashok Kumar Jan 2018

Endocrine And Hematobiochemical Profile Of Lambs Raised In A Semiaridregion With Different Growth Potentials During The Postweaning Period, Shiva Pratap Singh, Gopal Dass, Ramachandran Natesan, Yogender Kushwah, Nandini Sharma, Ashok Kumar

Turkish Journal of Veterinary & Animal Sciences

This study was conducted for establishment of the relationship of blood variables with growth rate of postweaned lambs. Eight lambs each of fast growth (FG; 11.6 ± 0.5 kg live wt. at weaning) and slow growth (SG; 7.7 ± 0.5 kg live wt. at weaning) were monitored fortnightly for endocrine and hematobiochemical variables along with parasitic load and growth performance. Recording of body weight (BW) and average daily gain (ADG) was performed monthly from birth to 180 days. Triiodothyronine (T3) and thyroxine (T4) were significantly (P < 0.05) higher while thyroid-stimulating hormone (TSH) and insulin-like growth factor-1 (IGF-1) were significantly (P < 0.05) lower in FG lambs compared to SG lambs. Blood cell counts, hematocrit, hemoglobin, mean corpuscular volume, and mean corpuscular hemoglobin were significantly (P < 0.05) higher in FG lambs compared to SG lambs. Except for the birth wt., the BW and ADG of FG lambs were significantly (P < 0.05) higher at all time points. Liver enzymes (alkaline phosphatase and alanine aminotransferase) and triglyceride were significantly (P < 0.05) higher in SG lambs compared to FG lambs. These findings indicate a significant influence of growth rate on peripheral concentrations of endocrine and some hematobiochemical variables in lambs. These selected variables can be used for early identification and culling of slow-growing lambs for better economic return to lamb producers.

Go to article

A Case Report Of Apatemon Gracilis (Szidat, 1928) Infectionin Domestic Geese In Mainland China, Dandan Liu, Zhennan Zhuo, Jianping Tao, Jinjun Xu Jan 2018

A Case Report Of Apatemon Gracilis (Szidat, 1928) Infectionin Domestic Geese In Mainland China, Dandan Liu, Zhennan Zhuo, Jianping Tao, Jinjun Xu

Turkish Journal of Veterinary & Animal Sciences

This is the first report of the diagnosis and treatment of Apatemon gracilis infection in domestic geese in mainland China confirmed at the molecular level. The mortality of geese reached 10% (150/1500). Necropsy examinations confirmed hemorrhagic inflammation of the small intestine and blood and catarrhal mucus in the enteric cavity. A large number of flukes were found in the first third of the small intestine, with one end buried in the intestinal mucosa, forming lesions at the absorption sites. The ITS-1 sequence of the parasites was amplified by polymerase chain reaction and sequence analysis confirmed that the isolated worms were …

Go to article

The Effects Of Three Different Prokinetic Drugs On The Motility Hormones Level In Lambs With Postoperative Ileus, Semi̇h Altan, Kaan Dönmez, Feray Altan, Fahretti̇n Alkan Jan 2018

The Effects Of Three Different Prokinetic Drugs On The Motility Hormones Level In Lambs With Postoperative Ileus, Semi̇h Altan, Kaan Dönmez, Feray Altan, Fahretti̇n Alkan

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate the effects of the three different prokinetic agents, namely erythromycin, lidocaine, and metoclopramide in lambs with postoperative ileus (POI) using motilin and ghrelin, which are known as motility markers. Twenty lambs were allocated to 4 groups of 5 lambs each. An enterotomy was performed on the ileum of each lamb. Erythromycin (8.8 mg/kg), metoclopramide (0.2 mg/kg), and saline (2 mL) were administered as single dose IM before surgery in the ERT, MET, and CNTR groups, respectively. Lidocaine was administered to the LID group, both as a bolus before (1.3 mg/kg IV) and …

Go to article

Comparative Study Of Growth Patterns In Seven Strains Of Japanese Quail Using Nonlinear Regression Modeling, Hadi Farajiarough, Mohammad Rokouei, Ali Maghsoudi, Mahmoud Ghazaghi Jan 2018

Comparative Study Of Growth Patterns In Seven Strains Of Japanese Quail Using Nonlinear Regression Modeling, Hadi Farajiarough, Mohammad Rokouei, Ali Maghsoudi, Mahmoud Ghazaghi

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to compare the growth pattern of seven strains of Japanese quail including Wild, Italian Speckled, Tuxedo, Scarlett, English white, White button, and A&M Texas by nonlinear growth functions including Gompertz, Richards, logistic, Lopez, and Weibull functions. The body weights of the unselected randomly bred populations of these strains were measured weekly from 1 to 42 days of age and then used to fit functions. The fitness of each function was assessed by statistics including the mean square error, Akaike information criterion, Bayesian information criterion, and adjusted coefficient of determination. The results showed that Gompertz …

Go to article

Molecular Detection Of Virulent Mannheimia Haemolytica And Pasteurella Multocida In Lung Tissues Of Pneumonic Sheep From Semiarid Tropics, Rajasthan, India, Fateh Singh, Ganesh Gangaram Sonawane, Rajendra Kumar Meena Jan 2018

Molecular Detection Of Virulent Mannheimia Haemolytica And Pasteurella Multocida In Lung Tissues Of Pneumonic Sheep From Semiarid Tropics, Rajasthan, India, Fateh Singh, Ganesh Gangaram Sonawane, Rajendra Kumar Meena

Turkish Journal of Veterinary & Animal Sciences

The present study was planned to detect the genetic elements of Mannheimia haemolytica and Pasteurella multocida in pneumonic sheep lungs. Pneumonia was diagnosed on the basis of gross pathological lesions. Lung tissues were collected at necropsy of sheep (n = 96) and subjected to isolation of total DNA. The M. haemolytica-specific PHSSA and Rpt2 genes, and the P. multocidaspecific KMT1 and the Omp87 genes were amplified using polymerase chain reaction (PCR). A housekeeping gene targeting the sheep cellular mitochondrial 12S ribosomal DNA was used as an internal control. PCR reactions were optimized using the positive and negative controls. Gene-specific PCR …

Go to article

Investigation Of The Efficiency And Safety Of Tilmicosin Phosphate In Treating Experimentalmycoplasmal Infections In Pigs, Xiaohui Zhang, Jinzhe Pan, Ning Wu, Shu Tang, Xiangdong Lei, Yangyang Sun, Joerg Hartung, Endong Bao Jan 2018

Investigation Of The Efficiency And Safety Of Tilmicosin Phosphate In Treating Experimentalmycoplasmal Infections In Pigs, Xiaohui Zhang, Jinzhe Pan, Ning Wu, Shu Tang, Xiangdong Lei, Yangyang Sun, Joerg Hartung, Endong Bao

Turkish Journal of Veterinary & Animal Sciences

In order to evaluate the in vivo therapeutic effect of oral administration of tilmicosin phosphate on mycoplasmal pneumonia in swine and its safety for the infected swine, the model of mycoplasmal pneumonia disease in swine was established by artificial infection, and indices such as efficiency, cure rate, death rate, the score of lung lesion, and the routine blood tests, blood biochemistry, and routine urine tests of tested swine were determined. The results showed that all of the dosage groups of 100 mg/L, 80 mg/L, 60 mg/L of 10% tilmicosin phosphate soluble powder demonstrated distinct therapeutic effects on mycoplasmal pneumonia in …

Go to article

Effects Of The Supplementation Of Lamb Rations With Oregano Essential Oil On Theantimicrobial And Antioxidant Metabolism In Meat, Hali̇t İmi̇k, Sevda Urçar, Meryem Aydemi̇r Atasever, Recep Gümüş, Hayrunni̇sa Özlü Jan 2018

Effects Of The Supplementation Of Lamb Rations With Oregano Essential Oil On Theantimicrobial And Antioxidant Metabolism In Meat, Hali̇t İmi̇k, Sevda Urçar, Meryem Aydemi̇r Atasever, Recep Gümüş, Hayrunni̇sa Özlü

Turkish Journal of Veterinary & Animal Sciences

Although oregano essential oil has common use in the cosmetics, pharmaceutical, and food sectors, information on its effects on meat quality and shelf life, when incorporated into lamb feed rations, is scarce. In this study, the effects of oregano essential oil (OEO) in feed on the water activity, pH, lipid peroxidation, color parameters, and microbial counts of the Musculus longissimus dorsi (MLD) were investigated. The control group was fed a basal ration and the OEO1 and OEO2 groups were fed a basal ration supplemented with 200 mg/kg and 400 mg/kg OEO, respectively. Akkaraman lambs were fed experimental rations for a …

Go to article

A Stereological Study On Calculation Of Volume Values Of The Cervical Spinalsegments In Ducks, Gamze Çakmak, Hüseyi̇n Karadağ, Zafer Soygüder, Murat Çeti̇n Rağbetli̇, Serkan Yildirim, Haci Keleş Jan 2018

A Stereological Study On Calculation Of Volume Values Of The Cervical Spinalsegments In Ducks, Gamze Çakmak, Hüseyi̇n Karadağ, Zafer Soygüder, Murat Çeti̇n Rağbetli̇, Serkan Yildirim, Haci Keleş

Turkish Journal of Veterinary & Animal Sciences

In the present study, volume values of the cervical segments in the spinal cords of adult ducks weighing 3-4 kg were investigated. Volume values of the grey matter and white matter in the cervical segment of the spinal cord of the ducks were examined stereologically. Ten ducks (genus Anas) without regarding the sex of the animals. All animals were perfused using 10% formaldehyde. The animals were kept in 10% formaldehyde for 1 week to ensure fixation. The ducks were then dissected. The cervical segments were uncovered by removing the cervical vertebrae. Tissue samples were obtained from each of the cervical …

Go to article

The Effect Of Obstructive Sleep Apnea Syndrome On The Central Auditory System, Ayşe İri̇z, Mehmet Düzlü, Oğuz Köktürk, Yusuf Kemal Kemaloğlu, Faki̇h Ci̇hat Eravci, Işik Si̇bel Küçükünal, Recep Karamert Jan 2018

The Effect Of Obstructive Sleep Apnea Syndrome On The Central Auditory System, Ayşe İri̇z, Mehmet Düzlü, Oğuz Köktürk, Yusuf Kemal Kemaloğlu, Faki̇h Ci̇hat Eravci, Işik Si̇bel Küçükünal, Recep Karamert

Turkish Journal of Medical Sciences

Background/aim: Obstructive sleep apnea syndrome (OSAS) is a disease characterized by repeated hypoxia attacks during sleep. The effect of hypoxia on the central nervous system is a well-known entity. In this study we aimed to investigate the effect of OSAS on the central auditory system. Materials and methods: Twenty-one OSAS patients diagnosed by polysomnography (PSG) and 10 control subjects were included in the study. After a thorough otorhinolaryngology examination, all subjects underwent pure tone audiometry (250 to 8000 Hz frequency). The subjects with normal otoscopic examination and hearing threshold were included in the study. All participants underwent speech discrimination analyses …

Go to article

Prognostic Value Of Interferon-Gamma, Interleukin-6, And Tumor Necrosis Factor-Alpha In The Radiation Response Of Patients Diagnosed With Locally Advanced Non-Small-Cell Lung Cancer And Glioblastoma Multiforme, Çi̇ğdem Damla Deni̇z, Mehmet Gürbi̇lek, Mehmet Koç Jan 2018

Prognostic Value Of Interferon-Gamma, Interleukin-6, And Tumor Necrosis Factor-Alpha In The Radiation Response Of Patients Diagnosed With Locally Advanced Non-Small-Cell Lung Cancer And Glioblastoma Multiforme, Çi̇ğdem Damla Deni̇z, Mehmet Gürbi̇lek, Mehmet Koç

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the effect of chemoradiotherapy (CRT) on interferon-gamma (IFN-γ), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α), which are critical markers of the clinical radiation response of patients with locally advanced non-small-cell lung cancer (NSCLC) and glioblastoma multiforme (GBM). Materials and methods: Thirty patients who were treated with CRT and 20 healthy controls were prospectively evaluated. Circulating levels of cytokines were measured by enzyme-linked immunosorbent assay procedure. Post-CRT and pre-CRT levels were compared. Results: Post-CRT, TNF-α and IFN-γ levels were significantly lower than pre-CRT levels in the NSCLC and GBM groups, respectively. The statistical analysis did …

Go to article

Biofilm Formation In Uropathogenic Escherichia Coli: Association With Adhesion Factor Genes, Hojjatolah Zamani, Ali Salehzadeh Jan 2018

Biofilm Formation In Uropathogenic Escherichia Coli: Association With Adhesion Factor Genes, Hojjatolah Zamani, Ali Salehzadeh

Turkish Journal of Medical Sciences

Background/aim: Biofilm formation is a major determinant factor in the development of urinary tract infections (UTIs) by uropathogenic Escherichia coli (UPEC). Several adhesion factors are involved in attachment of bacterial cells to the urinary tract and biofilm development. Materials and methods: The possible relationship between different adhesion factor genes (AFGs) and biofilm formation among UPEC isolates was investigated. Prevalence of different AFGs including fimA, fimH, papAH, papC, papEF, sfa-S, foc/G, and bmaE and their association to biofilm formation were investigated. Phenotypic expression of type 1 and P fimbriae was also investigated. Results: Our results showed that 84% of UPEC were …

Go to article

The Association Of Neuropathic Pain And Disease Activity, Functional Level, And Quality Of Life In Patients With Ankylosing Spondylitis: A Cross-Sectional Study, Duygu Geler Külcü, Sevi̇lay Batibay, Gülcan Öztürk Chatip Chousein Achmet, Ni̇lgün Mesci̇ Jan 2018

The Association Of Neuropathic Pain And Disease Activity, Functional Level, And Quality Of Life In Patients With Ankylosing Spondylitis: A Cross-Sectional Study, Duygu Geler Külcü, Sevi̇lay Batibay, Gülcan Öztürk Chatip Chousein Achmet, Ni̇lgün Mesci̇

Turkish Journal of Medical Sciences

Background/aim: Increased neuropathic pain (NP) symptoms are seen in rheumatologic diseases such as bromyalgia, osteoarthritis, and rheumatoid arthritis, but no studies have demonstrated a relationship between ankylosing spondylitis (AS) and NP except for a brain imaging study. e aim of this study was to estimate the presence of NP in patients with AS and to investigate how NP was related to disease activity, functional status, and quality of life. Materials and methods: A total of 100 AS patients (71 males and 29 females; median age: 37 years, range: 18?71 years) were included in the study. Pain (visual analog scale (VAS) …

Go to article

Changes Of Serum Spd-1 Levels In Hbeag-Positive Chronic Hepatitis B Patients With Entecavir Treatment And Correlation With Curative Effect, Chunhua Bi, Deyu Huang, Jing Jiang, Yueping Jiang, Hui Wang, Cheng Bian, Zibin Tian Jan 2018

Changes Of Serum Spd-1 Levels In Hbeag-Positive Chronic Hepatitis B Patients With Entecavir Treatment And Correlation With Curative Effect, Chunhua Bi, Deyu Huang, Jing Jiang, Yueping Jiang, Hui Wang, Cheng Bian, Zibin Tian

Turkish Journal of Medical Sciences

Background/aim: This study aimed to assess expression changes of serum sPD-1 levels in HBeAg-positive chronic hepatitis B patients with entecavir treatment and explore the correlation with the curative effect. Materials and methods: A total of 220 HBeAg-positive CHB patients and 207 healthy individuals were included. sPD-1 levels and virological and biochemical responses were assessed at baseline and at 12, 24, and 48 weeks in CHB patients a er antiviral therapy. Results: sPD-1 levels in HBeAg-positive CHB patients before treatment were signi cantly lower than those of healthy controls. After entecavir treatment, sPD-1 levels increased gradually over time. At 48 weeks …

Go to article

Risk Factor Assessment For Breast Cancer In North Cyprus: A Comprehensive Case-Control Study Of Turkish Cypriot Women, Ruqiya Pervaiz, Özgür Tosun, Hasan Besim, Nedi̇me Serakinci Jan 2018

Risk Factor Assessment For Breast Cancer In North Cyprus: A Comprehensive Case-Control Study Of Turkish Cypriot Women, Ruqiya Pervaiz, Özgür Tosun, Hasan Besim, Nedi̇me Serakinci

Turkish Journal of Medical Sciences

Background/aim: This case-control study aims to assess the strength of associations between reproductive, lifestyle, sociodemographic, and dietary factors as well as other potential breast cancer risks and breast cancer (BC) in a North Cyprus population. Materials and methods: The study includes 408 BC patients and 412 age-matched controls recruited from Near East Hospital and Dr. Burhan Nalbantoglu State Hospital in North Cyprus. Information regarding clinical and epidemiological characteristics was collected through a standardized interview. Age-adjusted odds ratios (ORs) and 95% con dence intervals (CIs) were calculated by logistic regression before and a er adjusting for the potential confounders. Results: In …

Go to article

Increased Micronucleus Count Predicts Malignant Behavior In Pleural Effusion Fluid, Tuba Di̇lay Kökenek Ünal, İpek Çoban Jan 2018

Increased Micronucleus Count Predicts Malignant Behavior In Pleural Effusion Fluid, Tuba Di̇lay Kökenek Ünal, İpek Çoban

Turkish Journal of Medical Sciences

Background/aim: Micronucleus (MN) frequency is used as a biomarker of chromosomal damage, genome instability, and cancer risk. e aim of this study was to evaluate the diagnostic usefulness of MN frequency to di erentiate between malignant and benign pleural e usion samples. Materials and methods: Retrospectively, 78 pleural uid cytology samples (including 20 cases of benign reactive mesothelial cells, 22 cases of suspicious cytology, and 36 cases of malignant cytology) were examined. e number of micronucleated cells in 1000 well- preserved cells was counted. Statistical tests were performed to compare the study groups. Recover operating characteristics (ROC) curve analysis was …

Go to article

Microbiological And Clinical Data Analysis Of 32 Patients With Nocardia Infections In Yantai, Hong-Xia Yu, Ming Liu, Zeng-Hui Pu, Yan Liu, Mao-Mao Zhao Jan 2018

Microbiological And Clinical Data Analysis Of 32 Patients With Nocardia Infections In Yantai, Hong-Xia Yu, Ming Liu, Zeng-Hui Pu, Yan Liu, Mao-Mao Zhao

Turkish Journal of Medical Sciences

Background/aim: Nocardia is an opportunistic pathogen that mostly a ects hosts with immune de ciencies. Recently, the widespread use of immunosuppressive agents and antitumor drugs has led to an increasing number of Nocardia infections being reported. However, it is di cult to con rm this diagnosis owing to the slow growth of the bacterium and its complex resultant clinical manifestations, potentially delaying treatment and increasing mortality. us, further knowledge on the clinical characteristics of Nocardia infection is required. Hence, this study aimed to review the demographics, comorbidities, clinical presentation, microbiology, treatment, and outcomes of Nocardia infections in Yantai. Materials and …

Go to article

Increased Concentrations Of Serum Nesfatin-1 Levels In Childhood With Idiopathic Chronic Malnutrition, Sezer Acar, Gönül Çatli, Tuncay Küme, Hale Ünver Tuhan, Özlem Gürsoy Çalan, Korcan Demi̇r, Ece Böber, Ayhan Abaci Jan 2018

Increased Concentrations Of Serum Nesfatin-1 Levels In Childhood With Idiopathic Chronic Malnutrition, Sezer Acar, Gönül Çatli, Tuncay Küme, Hale Ünver Tuhan, Özlem Gürsoy Çalan, Korcan Demi̇r, Ece Böber, Ayhan Abaci

Turkish Journal of Medical Sciences

Background/aim: Nesfatin-1, an anorexigenic molecule, seems to play a role in appetite regulation and energy homeostasis. e goal of this study was to evaluate the relation of nesfatin-1 with anthropometric and metabolic (ghrelin, leptin) parameters in children with idiopathic chronic malnutrition. Materials and methods: The study included 37 underweight and 38 healthy children who were similar regarding age, sex, and pubertal status. Anthropometric and biochemical (nesfatin-1, ghrelin, and leptin levels) variables were assessed. Results: A total of 37 underweight subjects (mean age 10.5 ± 2.6 years) and 38 heathy subjects (mean age 10.3 ± 2.3 years) were recruited. Underweight children …

Go to article

The Relation Between Isolated Micropenis In Childhood With Cag And Ggn Repeat Polymorphisms In The Androgen Receptor Gene, Esra Tuğ, Sezen Günteki̇n Ergün, Mehmet Ali̇ Ergün, Fatma Ni̇hal Di̇lek, Ferda Emri̇ye Perçi̇n Jan 2018

The Relation Between Isolated Micropenis In Childhood With Cag And Ggn Repeat Polymorphisms In The Androgen Receptor Gene, Esra Tuğ, Sezen Günteki̇n Ergün, Mehmet Ali̇ Ergün, Fatma Ni̇hal Di̇lek, Ferda Emri̇ye Perçi̇n

Turkish Journal of Medical Sciences

Background/aim: In micropenis cases accompanied by external genital abnormalities such as hypospadias and cryptorchidism, infertility and spermatogenic failures have been reported to correlate with androgen receptor (AR) gene CAG and GGN repeat polymorphisms. While there is one study on isolated micropenis and CAG repeats, no study related to GGN repeats has been reported. We investigated the relation between CAG and GGN repeats in the AR gene with development of penis length in boys with isolated micropenis. Materials and methods: A total of 24 Turkish boys with isolated micropenis (

Go to article

Effects Of Di Erent Drug Treatments On The Proliferation Of Human Ovarian Carcinoma Cell Line Mdah-2774, Şule Ayla, Ayhan Bi̇li̇r, Ahmet Şenol Ertürkoğlu, Gamze Tanriverdi̇, Burak Cem Soner, Kenan Sofuoğlu, Laura Ghisolfi, Gülperi̇ Öktem Jan 2018

Effects Of Di Erent Drug Treatments On The Proliferation Of Human Ovarian Carcinoma Cell Line Mdah-2774, Şule Ayla, Ayhan Bi̇li̇r, Ahmet Şenol Ertürkoğlu, Gamze Tanriverdi̇, Burak Cem Soner, Kenan Sofuoğlu, Laura Ghisolfi, Gülperi̇ Öktem

Turkish Journal of Medical Sciences

Background/aim: In this study, the e ects of resveratrol as a natural polyphenol compound, gemcitabine as an antimetabolite that has nucleoside structure analogous to deoxycytidine, and para-aminophenol-derived paracetamol were investigated with single and combined applications in monolayers of the MDAH-2774 human ovarian cancer cell line. Materials and methods: Drugs were evaluated in cell culture with respect to cell proliferation, cell cytotoxicity (trypan blue dye exclusion test), synthesis phase of cell cycle, and cell structure in 24, 48, 72, and 96 h. Result: Resveratrol and gemcitabine diminished both cell proliferation and cell cycle synthesis phase indication in monolayer cell cultures (P < 0.05). All combination groups showed similar e ects that were mainly more e ective in respect to single usage of resveratrol and gemcitabine in monolayer cell cultures. Conclusion: The effects of gemcitabine, resveratrol, and paracetamol were investigated in monolayers of the MDAH-2774 human ovarian cancer cell line and a decrease in cell number in cell cycle synthesis phase, prevention of cell proliferation, and destruction of cell structure were observed.

Go to article

The Impact Of Plasma Socs3 Levels And Endometrialleukocytes On Unexplained Infertility, Zehra Sema Özkan, Şükri̇ye Derya Deveci̇, Nusret Akpolat, Nafi̇ye Fulya İlhan, Mehmet Şi̇mşek, Hüseyi̇n Ti̇murkan Jan 2018

The Impact Of Plasma Socs3 Levels And Endometrialleukocytes On Unexplained Infertility, Zehra Sema Özkan, Şükri̇ye Derya Deveci̇, Nusret Akpolat, Nafi̇ye Fulya İlhan, Mehmet Şi̇mşek, Hüseyi̇n Ti̇murkan

Turkish Journal of Medical Sciences

Background/aim: To investigate the possible differences in endometrial leukocyte subtype distribution between women with unexplained infertility and normal fertile women and to determine whether there is a correlation between endometrial leukocyte counts and plasma cytokine levels in unexplained infertility. Materials and methods: This case-control study involved 79 infertile and 40 fertile women. Peripheral venous blood samples and endometrial samples were obtained on day 21 of the menstrual cycle. Plasma interleukin-4 (IL4), IL6, IL10, IL17, IL35, interferongamma (IFN-g), tumor necrosis factor-alpha (TNF-a), transforming growth factor-beta (TGF-b), and suppressor of cytokine signaling-3 (SOCS3) levels were determined by enzyme-linked immunosorbent assay. Endometrial CD8, …

Go to article

Visfatin Levels In Hormonally Inactive Adrenal Adenoma And Their Association Withmetabolic Parameters, Alp Atasoy, Evri̇m Çakir, Süleyman Ahbab, Yasemi̇n Erdoğan Döventaş, Maci̇t Koldaş, Hayri̇ye Esra Ataoğlu, Mustafa Yeni̇gün Jan 2018

Visfatin Levels In Hormonally Inactive Adrenal Adenoma And Their Association Withmetabolic Parameters, Alp Atasoy, Evri̇m Çakir, Süleyman Ahbab, Yasemi̇n Erdoğan Döventaş, Maci̇t Koldaş, Hayri̇ye Esra Ataoğlu, Mustafa Yeni̇gün

Turkish Journal of Medical Sciences

Background/aim: In parallel with increased frequency and higher quality of imaging techniques, the prevalence of adrenal adenoma has gradually increased. However, despite the growing incidence, the metabolic and tumorigenesis processes involved in its etiology are still unclear. Although visfatin has been reported to be associated with inflammation and tumorigenesis, its role in adrenal adenoma has not yet been investigated. Therefore, the present study was performed with an aim to evaluate visfatin levels and cardiometabolic risk factors in patients with adrenal adenoma. Materials and methods: Thirty patients recently diagnosed with adrenal adenoma along with 30 healthy participants were studied in a …

Go to article

Early Postoperative Follow-Up After Craniosynostosis Surgery, Ebru Ati̇ke Ongun, Oğuz Dursun, Mehmet Sai̇m Kazan, Banu Nur, Ercan Mihçi Jan 2018

Early Postoperative Follow-Up After Craniosynostosis Surgery, Ebru Ati̇ke Ongun, Oğuz Dursun, Mehmet Sai̇m Kazan, Banu Nur, Ercan Mihçi

Turkish Journal of Medical Sciences

Background/aim: Declined morbidity rates after craniosynostosis surgery indicate bypassing the pediatric intensive care unit (PICU) course to minimize treatment costs and bed usage. The aim of this study is to examine the incident rates of PICU admission and assess its necessity. Materials and methods: A retrospective analysis of 41 patients (operated on by open surgical techniques) between July 2011 and December 2015 was carried out. Intraoperative/postoperative vital signs, hemodynamic and metabolic parameters, estimated blood loss (EBVloss), blood transfusions, length of PICU, and hospitalizations were recorded. Results: Major and minor events reached 51.2% and 82.9%, respectively. EBVloss within 24 h was …

Go to article

Ankaferd Blood Stopper With Antibiofilm Potential Successfully Inhibits The Extracellularmatrix Degradation Enzymes And Promotes Wound Healing Of 3t3 Fibroblasts In Vitro, Ruki̇ye Boran, Tuba Baygar, Nurdan Saraç, Aysel Uğur Jan 2018

Ankaferd Blood Stopper With Antibiofilm Potential Successfully Inhibits The Extracellularmatrix Degradation Enzymes And Promotes Wound Healing Of 3t3 Fibroblasts In Vitro, Ruki̇ye Boran, Tuba Baygar, Nurdan Saraç, Aysel Uğur

Turkish Journal of Medical Sciences

Background/aim: The potential inhibitory effects of Ankaferd Blood Stopper (ABS) against biofilm formation of oral microorganisms and its capacity for collagenase, hyaluronidase, and elastase inhibitions that have important roles in wound healing have been investigated. Materials and methods: The wound healing potential was determined by its inhibition ability on collagenase, hyaluronidase, and elastase enzyme activities and was evaluated via scratch wound healing assay on murine 3T3 fibroblasts. The antibiofilm activity was tested against eight oral microorganisms using the crystal violet staining method. Results: At 10% ABS successfully inhibited the biofilm formation of the tested microorganisms. Enzyme inhibition analysis revealed that …

Go to article

Tuberculin Skin Test Response In Patients With Juvenile Idiopathic Arthritis Onanti-Tnf Therapy, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇c, Muhammet Köşker, Ömer Kiliç, Yildiz Camcioğlu, Haluk Cezmi̇ Çokuğraş, Necla Akçakaya, Betül Sözeri̇, Özgür Kasapçopur Jan 2018

Tuberculin Skin Test Response In Patients With Juvenile Idiopathic Arthritis Onanti-Tnf Therapy, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇c, Muhammet Köşker, Ömer Kiliç, Yildiz Camcioğlu, Haluk Cezmi̇ Çokuğraş, Necla Akçakaya, Betül Sözeri̇, Özgür Kasapçopur

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to evaluate the effect of biologic drugs on the tuberculin skin test in patients with juvenile idiopathic arthritis. Materials and methods: A total of 234 biologic drug-using juvenile idiopathic arthritis patients and 45 healthy controls were enrolled in the study. The tuberculin skin test results of the patients, which had been routinely provided during follow-up, were obtained from the patient files. Tuberculin skin test values of ≥ 5 mm were considered to be positive. Results: The mean diameter of tuberculin skin test induration was 4.99 ± 6.84 mm (IQR: 0-10 mm) and 7.83 …

Go to article

Pulmonary Valve Replacement In Patients With Repaired Tetralogy Of Fallot: Early Results For Recovery Of Right Ventricular Dilatation And Qrs Duration, Ahmet Arnaz, Ayla Oktay, Serdar Akansel, Di̇lek Altun, Abdullah Doğan, Piotr Serban, Arda Saygili, Yusuf Kenan Yalçinbaş, Ayşe Sarioğlu, Cafer Tayyar Sarioğlu Jan 2018

Pulmonary Valve Replacement In Patients With Repaired Tetralogy Of Fallot: Early Results For Recovery Of Right Ventricular Dilatation And Qrs Duration, Ahmet Arnaz, Ayla Oktay, Serdar Akansel, Di̇lek Altun, Abdullah Doğan, Piotr Serban, Arda Saygili, Yusuf Kenan Yalçinbaş, Ayşe Sarioğlu, Cafer Tayyar Sarioğlu

Turkish Journal of Medical Sciences

Background/aim: Although pulmonary valve replacement (PVR) improves ventricular function and symptoms, the benefit and optimal timing of PVR are controversial. This study aimed to evaluate early response to PVR for right ventricle (RV) dilatation and QRS duration. Materials and methods: Retrospective analysis was performed for 32 patients with repaired tetralogy of Fallot (TOF) between March 2005 and October 2017. The differences between preoperative and postoperative changes in echocardiographic parameters, clinical symptoms, and QRS duration were evaluated. Results: There were no in-hospital or late deaths. Mean age at the time of PVR was 16.57 ± 7.97 years. The interval between TOF …

Go to article

Is 72 H Of Antimicrobial Prophylaxis Better Than 24 H In Elective Gastric Cancer Surgery?, Xiang Zia, Gang Zhao, Wei Ling, Fengrong Yu Jan 2018

Is 72 H Of Antimicrobial Prophylaxis Better Than 24 H In Elective Gastric Cancer Surgery?, Xiang Zia, Gang Zhao, Wei Ling, Fengrong Yu

Turkish Journal of Medical Sciences

Background/aim: The optimum duration of antimicrobial prophylaxis in elective gastric cancer surgery is still not yet established. The aim of this study is to evaluate the efficacy of 24 h or 72 h of antimicrobial prophylaxis for preventing postoperative infection. Materials and methods: Between July 2016 and January 2018, 990 gastric cancer patients undergoing surgery with D2 lymphadenectomy in Ren Ji Hospital were classified into 24-h or 72-h antimicrobial prophylaxis groups. The incidence of postoperative infection complications was compared. Results: A total of 990 patients (24-h antimicrobial prophylaxis, 708 cases; 72-h antimicrobial prophylaxis, 282 cases) were analyzed. Surgical site infection …

Go to article

The Role Of Soluble Urokinase Plasminogen Activator Receptor (Supar) As An Indicator Of The Severity Of Acute Pancreatitis, Kadi̇r Küçükceran, Mehmet Ergi̇n, İbrahi̇m Kilinç, Adnan Karai̇brahi̇moğlu, Tamer Çolak, Alpay Tuncar, Zerri̇n Defne Dündar, Sedat Koçak, Abdullah Sadik Gi̇ri̇şgi̇n, Mehmet Gül, Başar Cander Jan 2018

The Role Of Soluble Urokinase Plasminogen Activator Receptor (Supar) As An Indicator Of The Severity Of Acute Pancreatitis, Kadi̇r Küçükceran, Mehmet Ergi̇n, İbrahi̇m Kilinç, Adnan Karai̇brahi̇moğlu, Tamer Çolak, Alpay Tuncar, Zerri̇n Defne Dündar, Sedat Koçak, Abdullah Sadik Gi̇ri̇şgi̇n, Mehmet Gül, Başar Cander

Turkish Journal of Medical Sciences

Background/aim: Soluble urokinase plasminogen activator receptor (suPAR) has been reported to have a positive correlation with the activation degree of the immune system. This study's aim is to investigate the efficiency of SuPAR serum levels in acute pancreatitis (AP) patients in determining the severity of disease. Materials and methods: This prospective research involves patients who arrived at the emergency service, were over 18 years old, had nontraumatic abdominal pain and diagnosis of AP, and agreed to join the study. Demographic characteristics, contact information, laboratory and imaging test parameters, Ranson's criteria, the Balthazar Severity Index, the Rapid Acute Physiologic Score (RAPS), …

Go to article

Evaluation Of Platelet Parameters And Neutrophil/Lymphocyte Ratio During Omalizumab Treatment In Patients With Severe Chronic Spontaneous Urticaria, Ragip Ertaş, Kemal Özyurt, Çi̇ğdem Karakükcü, Muhammet Reşat Akkuş, Emi̇n Özlü, Atil Avci, Mustafa Atasoy Jan 2018

Evaluation Of Platelet Parameters And Neutrophil/Lymphocyte Ratio During Omalizumab Treatment In Patients With Severe Chronic Spontaneous Urticaria, Ragip Ertaş, Kemal Özyurt, Çi̇ğdem Karakükcü, Muhammet Reşat Akkuş, Emi̇n Özlü, Atil Avci, Mustafa Atasoy

Turkish Journal of Medical Sciences

Background/aim: Spontaneous wheals and/or angioedema lasting longer than six weeks are described as chronic spontaneous urticaria (CSU). Omalizumab is used for the treatment of antihistamine-resistant CSU. The neutrophil-lymphocyte ratio (NLR), platelet- lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet distribution width (PDW) are considered important indicators of inflammation and platelet activation in chronic diseases. We aimed to determine the NLR, PLR, MPV, and PDW levels in patients with CSU compared with healthy controls. We also aimed to investigate the effects of omalizumab therapy on these parameters in CSU patients. Materials and methods: This hospital-based, retrospective study included 143 patients …

Go to article

The Effect Of Generalized Seizure Activity On Ischemia-Induced Cardiac Arrhythmias And Myocardial Injury With Histopathological Evaluation In Anesthetized Rats, Ersöz Gonca, Fi̇gen Barut, Deni̇z Şahi̇n Jan 2018

The Effect Of Generalized Seizure Activity On Ischemia-Induced Cardiac Arrhythmias And Myocardial Injury With Histopathological Evaluation In Anesthetized Rats, Ersöz Gonca, Fi̇gen Barut, Deni̇z Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: Epileptic seizure leads to sudden unexpected death in epilepsy (SUDEP) among affected patients. The causes of SUDEP are still unclear. The aim of this study was to research the effect of epilepsy on myocardial injury and arrhythmias during experimentally induced acute myocardial ischemia. Materials and methods: Wistar albino rats were divided into four groups: sham, pentylentetrazole (PTZ) + sham, ischemia, and PTZ + ischemia groups. PTZ (65 mg/kg, ip) was given 2 h before ischemia. Seizure scoring was conducted by evaluating the PTZ-induced behavioral changes in the rats. The left main coronary artery was ligated in anesthetized rats for …

Go to article

Expression Changes Of Cd177 And Mpo As Novel Biomarkers In Lung Tissue Ofclp Model Rats, Azadeh Rasooli, Elham Ghafari, Hamed Saeidi, Saba Miri Jan 2018

Expression Changes Of Cd177 And Mpo As Novel Biomarkers In Lung Tissue Ofclp Model Rats, Azadeh Rasooli, Elham Ghafari, Hamed Saeidi, Saba Miri

Turkish Journal of Medical Sciences

Background/aim: Sepsis is an unregulated systemic response to microbial invasion that can lead to multiple organ failure. This study aims at investigating the relationships among myeloperoxidase (MPO) and CD177 in major organ systems including whole blood, liver, and lung tissues in septic rats. Materials and methods: Sepsis was induced by cecal ligation and puncture (CLP) in female Wistar rats. Whole blood, liver, and lung samples were obtained from rats of 3 groups (n = 10 for each group, n total = 30: control as a wild-type group, laparotomy group (LAP), and CLP). Gene expression of MPO and CD177 in targeted …

Go to article

First Prev Next Last