Digital Commons Network^™

Shame In The Presence Or Absence Of God In Stephen Ministry, Richard Tamas

Theses and Dissertations (Comprehensive)

This hermeneutical phenomenological study explores the lived experience of shame in relation to the presence or absence of God in the caregiving process of Stephen Ministry. Stephen Ministers are trained Christian caregivers who walk side-by-side with those who are struggling in a congregation. Stephen Ministers are trained by Stephen Leaders who have completed the Stephen Ministry Leadership training program. A concern for an assurance of quality of care led to the research question: what is the lived experience of unacknowledged or unprocessed shame in the presence or absence of God experienced by Stephen Ministers who offer Christian care? The foundations …

Evidence For Extra-Gastric Expression Of The Proton Pump H+/K+ -Atpase In The Gills And Kidney Of The Teleost Oreochromis Niloticus, Ebtesam Barnawi

Theses and Dissertations (Comprehensive)

It is well known that stomach acid secretion by oxynticopeptic cells of the gastric mucosa is accomplished by the H⁺/ K⁺-ATPase (HKA), which is comprised of the HKα1 (gene: atp4a) and HKβ (gene: atp4b) subunits. However, the role of the HKA in extra-gastric organs such as the gill and kidney is less clear especially in fishes. This pump may contribute to active ion and/or acid-base regulation either through direct ion transport or through secondary transport proteins against unfavorable concentration gradients via the energy derived from ATP hydrolysis. In the present work I have demonstrated …

Drivers Of Post-Fire Vascular Plant Regeneration In The Conifer-Dominated Boreal Forest Of Southern Northwest Territories, Alison White

Theses and Dissertations (Comprehensive)

In recent years, climate warming has led to an increase in the severity and frequency of naturally occurring fires in boreal ecosystems globally. In 2014, an unprecedented 3.4 million hectares of boreal forest burned in the Northwest Territories (NWT). While much research has focused on post-fire succession of serotinous tree species such as Picea mariana (black spruce) and Pinus banksiana (jack pine), the understory community of vascular plants play an important role in ecosystem functioning but less is known about the response of this component of the system to changing fire regimes. Regeneration strategies such as the ability to resprout …

Men, Masculinity And Perceptions Of Higher Education Sexual Violence Programming: A Qualitative Analysis, Merry M. Snyder

Departmental Honors Projects

Research suggests that sexual assault on college campuses is very prevalent. Although institutions are taking measures towards prevention, social norms have left the role of men in addressing sexual violence under-examined. Through my two-part research, I examined the relationship between men and these systems. I first conducted interviews with Higher Education Professionals in the Upper Midwest to explore how the dominant forms of masculinity have played a role in campus programming. This research was concerned with how schools are engaging men on campus and addressing harmful forms of masculinity. The themes that emerged through these interviews provided the basis for …

Random Walks On Simple Two-Dimensional Manifolds, Tom Eichlersmith

Departmental Honors Projects

A C++ implementation of random walks is constructed with examples for the plane, sphere, and torus included. This package is available publicly, and can be expanded to different situations on the included surfaces as well as other surfaces. The random walks are studied by measuring how long they take to reach a pre-defined escape region on the surface. These escape regions and their interaction with the surface are what affect the behavior of the random walks the most.

Paleoecological Investigation Of The Effect Of Rainbow Trout Predation On Zooplankton Body Size And Community Composition, Michael E. Gilray

Departmental Honors Projects

Stocking fish for sport may induce food web cascades that impact the trophic state of lakes. Here, the practice of stocking rainbow trout into a Twin Cities metropolitan area lake (Square Lake) was examined to see if changes have occurred in the lake’s zooplankton community that could explain its declining water quality. Rainbow trout are size-selective predators that consume large-bodied herbivorous zooplankton (i.e., Daphnia pulicaria) and therefore may cause decreased phytoplankton grazing pressure and more eutrophic conditions. A paleoecological study was performed that compared the sediment record of Square Lake to that of a reference lake (Big Carnelian Lake) that …

Franz Boas And The Columbian Field Museum, Martin W. Peper

Departmental Honors Projects

The Late Nineteenth Century was a period of major flux within the world of American anthropology. Two major centers of power had emerged within the nascent field. Federally sponsored anthropologists clashed with academic institutions, especially those associated with Harvard’s Frederic Ward Putnam. These two bodies found themselves at odds over methodological design and the theoretical frameworks supporting their research. These issues would span the breadth of anthropology as a field, but nowhere was it more visible than in the scope of museum studies. Public displays of anthropological thought were the most direct way that scholars were able to present their …

The Behavioral Immune System: Homelessness As A Disease Marker, Anya O’Connor

Departmental Honors Projects

Alongside the biological immune system is the behavioral immune system that works to avoid infection by avoiding contact with potential disease. The behavioral immune system reacts to visual cues of potential disease, such as coughing or skin lesions, and promotes avoidance behavior via disgust reactions. It interacts with biological immune responses by influencing hormones such as Interleukin-6 and cortisol. The behavioral immune system has also been found to overgeneralize and react to cues, such as obesity, disability, and foreignness, that do not signal actual disease threat. The purpose of this study is to test if the behavioral immune system overgeneralizes …

Dna Extraction And Microsatellite Amplification Of Daphnia Pulicaria Resting Eggs: Analysis Of Allele Frequencies Through Time, Anna Ries

Departmental Honors Projects

A paleoecological approach allows for the study of genetic change in populations over longer periods of time than would be possible if one were sampling populations from year to year. Daphnia and other cladoceran zooplankton are amenable to this type of study because they produce diapausing embryos (ephippial eggs) when they sexually reproduce, and these resting eggs can remain viable for decades to centuries in lake sediments. This study uses paleoecological methods as well as a new methodology for ephippial DNA extraction and amplification to assay for genetic variation in ephippial eggs obtained from sediments of varying ages from Square …

Forensic Markers Of Lampricide Toxicity In Oncorhynchsus Mykiss, Chris White

Theses and Dissertations (Comprehensive)

The lampricide 3-trifluoromethyl-4-nitrophenol (TFM) has been used for decades to control invasive sea lamprey (Petromyzon marinus) populations in the Great Lakes, normally with little harm to other fish populations. However, due to the nature of lampricide treatments and the chemical properties of TFM, adverse effects to non-target fishes and non-target mortality occasionally occur. However, investigations of non-target mortality can be complex, particularly if fish deaths are not noticed immediately, due to decomposition of the carcasses. The objectives of this thesis were to expose rainbow trout (Oncorhynchsus mykiss) to TFM in order to: (i) identify forensic markers …

Confronting Sexism In Science, Technology, Engineering, And Math (Stem): What Are The Consequences?, Eden J.V. Hennessey

Theses and Dissertations (Comprehensive)

Disparaging remarks that female scientists are ‘Distractingly Sexy’ (Waxman, 2015) and ‘Too Pretty to Do Math’ t-shirts (Amazon.com) highlight the common belief that women in science, technology, engineering and math (STEM) violate perceived gender norms. However, by confronting these beliefs, women may incur a ‘double-dose’ of hostility; once for being present in science, and again because of the confrontation itself (Kaiser & Miller, 2001). Across three studies, this research tested how women confronting sexism in STEM contexts would elicit and anticipate social costs. Study 1 showed that male participants rated a hypothetical female confronter in STEM higher in bossiness and …

An Assessment Of The Plant And Mycorrhizal Community At Steeves Lake Shoreline, Colomac Mine, Nwt, Rebekah Hamp, Dr. Kevin Stevens

Theses and Dissertations (Comprehensive)

This study focused on the environmental impacts of mining and potential techniques to mitigate them. The goals of this study were to (1) Quantify vegetation and fungal colonization at a remediated mine site in northern Canada, and to determine if there were effects from petroleum hydrocarbon contamination, (2) Determine the response of northern plants inoculated with mycorrhizal fungi to diesel contamination. Mycorrhizal colonization was observed in field collected roots and trends in colonization and vegetation cover suggested that these communities were no longer impacted by residual contamination. Mean hyphal colonization of Elymus trachycaulus roots collected over two years was 47.3±3.8% …

Mechanotransduction Signaling In Podocytes From Fluid Flow Shear Stress., Tarak Srivastava, Hongying Dai, Daniel P. Heruth, Uri S. Alon, Robert E. Garola, Jianping Zhou, R Scott Duncan, Ashraf El-Meanawy, Ellen T. Mccarthy, Ram Sharma, Mark L. Johnson, Virginia J. Savin, Mukut Sharma

Manuscripts, Articles, Book Chapters and Other Papers

Recently, we and others have found that hyperfiltration-associated increase in biomechanical forces, namely, tensile stress and fluid flow shear stress (FFSS), can directly and distinctly alter podocyte structure and function. The ultrafiltrate flow over the major processes and cell body generates FFSS to podocytes. Our previous work suggests that the cyclooxygenase-2 (COX-2)-PGE2-PGE2 receptor 2 (EP2) axis plays an important role in mechanoperception of FFSS in podocytes. To address mechanotransduction of the perceived stimulus through EP2, cultured podocytes were exposed to FFSS (2 dyn/cm2) for 2 h. Total RNA from cells at the end of FFSS treatment, 2-h post-FFSS, and 24-h …

Pre-Clinical Activity Of Targeting The Pi3k/Akt/Mtor Pathway In Burkitt Lymphoma, Maria Bhatti, Thomas Ippolito, Cory Mavis, Juan Gu, Mitchell Cairo, Megan Lim, Matthew Barth

NYMC Faculty Publications

Though outcomes for pediatric Burkitt lymphoma (BL) have improved significantly in recent decades with intensive multi-agent chemotherapy and the addition of rituximab, chemotherapy resistance remains a significant impediment to cure following relapse. Activation of the PI3K/AKT pathway has been implicated in Burkitt lymphomagenesis and increased PI3K/AKT activation has been associated with worse outcomes in adults with aggressive B-cell non-Hodgkin lymphoma (B-NHL). Inhibitors of the PI3K/AKT pathway have been approved for the treatment of refractory indolent B-NHL and continue to be investigated for treatment of aggressive B-NHLs. We investigated the activation of the PI3K/AKT pathway in a cell line model of …

Unmasking Cost Growth Behavior: A Longitudinal Study, Cory N. D'Amico, Edward D. White, Jonathan D. Ritschel, Scott R. Kozlak

Faculty Publications

This article examines how cost growth factors (CGF) change over a program’s acquisition life cycle for 36 Department of Defense aircraft programs. Starting from Milestone B, the authors examine CGFs at five gateways: Critical Design Review, First Flight (FF), the end of Developmental Test and Evaluation (DT&E), Initial Operational Capability, and Full Operational Capability. Each CGF is assigned a color rating based upon the program’s cost growth: Green (low), Amber (moderate), or Red (high). Significant findings include dependencies among similar CGF color ratings and cost growth occurring primarily between FF and the end of DT&E during a program’s life cycle.

The Sage Model Of Social Psychological Research, Séamus A. Power, Gabriel M. Velez, Ahmad Qadafi, Joseph Tennant

College of Education Faculty Research and Publications

We propose a SAGE model for social psychological research. Encapsulated in our acronym is a proposal to have a synthetic approach to social psychological research, in which qualitative methods are augmentative to quantitative ones, qualitative methods can be generative of new experimental hypotheses, and qualitative methods can capture experiences that evade experimental reductionism. We remind social psychological researchers that psychology was founded in multiple methods of investigation at multiple levels of analysis. We discuss historical examples and our own research as contemporary examples of how a SAGE model can operate in part or as an integrated whole. The implications of …

What Is Teacher Agency?, Alcione N. Ostorga

Bilingual and Literacy Studies Faculty Publications

No abstract provided.

Estrogen-Dependent Epigenetic Regulation Of Soluble Epoxide Hydrolase Via Dna Methylation, Yang-Ming Yang, Dong Sun, Sharath Kandhi, Ghezal Froogh, Jian Zhuge, Wei-Hua Huang, Bruce D. Hammock, An Huang

NYMC Faculty Publications

To elucidate molecular mechanisms responsible for the sexually dimorphic phenotype of soluble epoxide hydrolase (sEH) expression, we tested the hypothesis that female-specific down-regulation of sEH expression is driven by estrogen-dependent methylation of the Ephx2 gene. Mesenteric arteries isolated from male, female, ovariectomized female (OV), and OV with estrogen replacement (OVE) mice, as well as the human cell line (HEK293T) were used. Methylation-specific PCR and bisulfite genomic sequencing analysis indicate significant increases in DNA/CG methylation in vessels of female and OVE compared with those of male and OV mice. The same increase in CG methylation was also observed in male vessels …

Application Of Microrna Markers For Early Detection Of Latent Tuberculosis Transitioning To Active Tuberculosis, Robert A. Ollar

NYMC Faculty Publications

No abstract provided.

Development Of Chitosan/Gelatin/Keratin Composite Containing Hydrocortisone Sodium Succinate As A Buccal Mucoadhesive Patch To Treat Desquamative Gingivitis, Zahra Davoudi, Mohammad Rabiee, Behzad Houshmand, Niloofar Eslahi, Kimia Khoshroo, Morteza Rasoulianboroujeni, Mohammadreza Tahriri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

The aim of this research was to develop chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis, which was fabricated through an environmental friendly process. Mucoadhesive films increase the advantage of higher efficiency and drug localization in the affected region. In this research, mucoadhesive films, for the release of hydrocortisone sodium succinate, were prepared using different ratios of chitosan, gelatin and keratin. In the first step, chitosan and gelatin proportions were optimized after evaluating the mechanical properties, swelling capacity, water uptake, stability, and biodegradation of the films. Then, keratin was added at different percentages …

A–C Estrogens As Potent And Selective Estrogen Receptor-Beta Agonists (Serbas) To Enhance Memory Consolidation Under Low-Estrogen Conditions, Alicia M. Hanson, K. L. Iresha Sampathi Perera, Jaekyoon Kim, Rajesh K. Pandey, Noreena Sweeney, Xingyun Lu, Andrea Imhoff, Alexander Craig Mackinnon, Adam J. Wargolet, Rochelle M. Van Hart, Karyn M. Frick, William A. Donaldson, Daniel S. Sem

Chemistry Faculty Research and Publications

Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings. The most potent and selective A–C estrogen is selective for activating ER relative to seven other nuclear hormone receptors, with a surprising 750-fold selectivity for the β over α isoform and with EC₅₀s of 20–30 nM in cell-based and direct binding assays. Comparison of potency in different assays suggests that the ER isoform selectivity is related to the …

Feasibility And Pilot Testing Of A Mindfulness Intervention For Frail Older Adults And Individuals With Dementia, Christine R. Kovach, Crystal-Rae Waltons, Lisa Sattell, Kimberly Rosenau, Sandeep Gopalakrishnan

College of Nursing Faculty Research and Publications

Mindfulness interventions have been beneficial for healthy adults and individuals experiencing a stressful medical or mental health diagnosis. The purposes of the current study were to: (a) determine feasibility of mindfulness for older adults in long-term residential settings, and (b) examine differences in outcomes between a mindfulness and cognitive activity. The current study is the first mindfulness study to include individuals in moderate and severe stages of dementia, and included 36 individuals with a range of cognitive abilities. A crossover design was used, and the intervention was feasible for continued practice by individuals with cognitive impairment. Statistically significant short-term changes …

Testing The Network Reset Hypothesis: Noradrenergic Modulation Of Hippocampal Representations, Stephanie L. Grella

Theses and Dissertations (Comprehensive)

The locus coeruleus (LC) responds to salience cues, including novelty, and sends a major noradrenergic projection to the hippocampal formation (HF). Novelty-associated LC activation may help to sculpt contextual representations in the HF, but modulatory influence of norepinephrine (NE) over HF representations remains poorly understood. One possible mechanism is that NE provides a “reset” signal causing the HF to recruit distinct neural populations, thereby providing a molecular switch to dictate if hippocampal circuits should generate new representations or update existing ones to incorporate novel information. This hypothesis suggests that NE release should cause the HF to recruit a unique population …

Navigating Risks Across Borders: The Lived Experiences Of Central American Women Migrants, Carla Angulo-Pasel

Theses and Dissertations (Comprehensive)

The journey for ‘unauthorized’ migrant women from the Northern Triangle of Central America (NTCA) through Mexico dangerous and violent. In hopes of achieving safe passage to the United States (U.S.), women migrants will have to navigate borders. In this dissertation, I use the concept of borders to reveal the gendered experiences of (im)mobility. I argue that navigating borders throughout the migratory journey is not simply about experiencing the risks and vulnerabilities associated with restrictive border enforcement policies and practices implemented by the nation-state. (Im)mobility for women migrants is equally about the boundaries and/or barriers that are created by oppressive systems …

The Role Of Channel Fens In Permafrost Degradation Induced Changes In Peatland Discharge At Scotty Creek, Nt, Lindsay Elena Stone

Theses and Dissertations (Comprehensive)

Permafrost degradation in the peat-rich southern fringe of the discontinuous permafrost zone is producing substantial changes to land cover with concomitant expansion of permafrost-free wetlands (bogs and fens) and shrinkage of forest supported by permafrost peat plateaus. Predicting discharge from headwater basins in this region depends on understanding and numerically representing the interactions between storage and discharge within and between the major land cover types, and how these interactions are changing. To better understand the implications of land cover change on wetland discharge, the hydrological behaviour of a channel fen in the headwaters of Scotty Creek, Northwest Territories, Canada, dominated …

Landscape Scale Spectral-Temporal Modelling Of Bamboo-Dominated Forest Succession Within The Atlantic Forest Of Southern Brazil, Clara Greig

Theses and Dissertations (Comprehensive)

Tropical and subtropical ecosystems have become vulnerable to biological invasion (i.e., bamboo) due to human induced forest fragmentation. Bamboo ecological processes have been found to impede forest development, resulting in a state of arrested succession, which has been found to significantly reduce biodiversity, thus contributing to biotic homogenization. In this study we use a semi-empirical approach to develop a community-level spatially explicit ecological process model (hybrid model) using a time-series of Landsat imagery to describe single-landscape scale ecological processes of a pervasive bamboo species (Merostachys skvortzovii) found throughout the Araucaria forest, a critically threatened subtype of Atlantic forest …

Stories As Sites Of Resistance: Reclaiming Men’S Narratives Of Concurrent Substance Use And Intimate Partner Violence, Stephanie Baker

Theses and Dissertations (Comprehensive)

This study examines men’s experiences and perceptions of concurrent substance use and intimate partner violence using qualitative methodology. Previous research on the relationship between these concerns has been primarily quantitative in nature and situated within two dominant perspectives (the medical model and feminism). The aim of this study was to explore men’s stories within social constructionist and postmodern frameworks to develop a more comprehensive understanding of their lived experiences with concurrent substance use and intimate partner violence.

Narrative methods were employed to collect and analyze the data. Purposive sampling located twelve men living in the Niagara Region, St. Mary’s, and …

Relationships Between Factors Influencing Biofilm Formation And Pathogen Retention In Complex Rhizosphere Microbial Communities, Aaron Coristine

Theses and Dissertations (Comprehensive)

Riparian wetlands are unique habitats facilitating all forms of life. The riverbanks of these environments provide ideal conditions for bacteria, plants, and higher organisms. Of particular interest to this research was the variation in microbial community structure at high, intermediate and poor water quality impacted areas. Assessing the capabilities of plants to retain microbial pathogens was identified. Root systems and corresponding soil are ideal locations for bacterial deposition, resulting in attachment at these areas. Biofilm production in these regions is important for long-term establishment, leading to persistence and potential naturalization. Opportunistic pathogens originating from mammalian fecal matter are introduced into …

Spatial Modelling And Wildlife Health Surveillance: A Case Study Of White Nose Syndrome In Ontario, Lauren Yee

Theses and Dissertations (Comprehensive)

Wildlife data is often limited by survey effort, small sample sizes, and spatial biases associated with collection and missing data. These factors can create unique challenges from a surveillance perspective when trying to extract spatial patterns of habitat suitability and disease distributions for conservation and management purposes. This thesis examined data quality from a wildlife health database in the context of spatial analysis of wildlife disease. Spatial analysis of the data to predict habitat suitability of bats and white nose syndrome afflicted bats was examined by using the MaxEnt modelling method. Methods to reduce spatial bias were examined and specific …

The Influence Of Physiological And Abiotic Factors On The Sensitivity Of The Sea Lamprey (Petromyzon Marinus) To The Lampricide 3-Trifluoromethyl-4-Nitrophenol (Tfm), Alexandra Muhametsafina

Theses and Dissertations (Comprehensive)

Invasive sea lamprey (Petromyzon marinus) in the Great Lakes are controlled using the pesticide (lampricide) 3-trifluoromethyl-4-nitrophenol (TFM), which is applied to nursery streams containing larval lamprey. The toxicity of TFM to lamprey is affected by various environmental and physiological factors, which can lead to residual lamprey that survive TFM treatment. The goal of this study was to investigate how abiotic (season and temperature) factors interacted with physiological parameters (whole body and tissue energy reserves) to influence TFM sensitivity in sea lamprey. Toxicity tests were conducted at different times of the year (spring, early and late summer, fall) and …