Digital Commons Network^™

Comparing Rates Of Women Leaders In Western Europe, Elizabeth Stark

Honors Projects

This article analyzes the rates of women leaders in conservative, green and right-wing parties in Western Europe. The genders of parliamentary leaders, founders and party leaders of these parties are examined to determine if women are over represented or under represented as political leaders in Western Europe.

La Guerra Civil En El Cine Español Contemporáneo: Nuevas Formas De Recordar, Sara Boyle

La BloGoteca de Babel

No abstract provided.

Effects Of Fixed And Malleable Views Of Intelligence And Attribution Of Controllability On Teacher Affects, Gary Beard

PCOM Psychology Dissertations

The classroom is a dynamic social setting where teachers respond affectively to student failure. Divergent affective reactions toward learning and achievement occur in teachers with fixed and malleable views of intelligence, which impact students’ self-esteem and expectations for future success. The present study explored teacher and student variables related to emotive classroom expression toward test failures of boys. View of intelligence as fixed or malleable, attribution of controllability (effort & ability) and student condition were measured and examined in relation to the affects frustration, sympathy, positive or negative feedback and expectations for future failure. Attributions of controllability (effort & ability) …

Cognitive Behavioral Therapy As A Supplemental Treatment For Adolescents With Learning Disabilities, Peter John Arsenault

PCOM Psychology Dissertations

This study explores cognitive behavioral therapy (CBT) as a supplemental treatment with a sample of adolescents with learning disabilities (LD). Research overwhelming reflects the theory that children and adolescents with LD are more likely to manifest anxious and depressive symptomology. CBT is an evidence based intervention for anxiety and depression. However, there is a gap in the knowledge of treating LD with CBT. The study hypothesizes the theory that maladaptive metacognitive interpretation of the LD diminishes the effects of the evidence based academic intervention. The study sought to explore whether or not adolescents with LD would experience enhanced academic and …

Attitudes And Knowledge Of Healthcare Providers Regarding Patients With Intellectual Disability And The Impact On Analogue Clinical Decision-Making, Alexandra Freed Santoro

PCOM Psychology Dissertations

Throughout their careers, physicians, particularly those in primary care settings, can expect to treat patients with intellectual disability (ID) across the lifespan. Nevertheless, little attention is given to preparing medical students to effectively treat patients with ID through education and clinical training opportunities. The purpose of this study was to examine how knowledge and attitudes toward patients with ID may impact analogue clinical decision-making at different stages of physician education and career. Included in the review of the current literature is research relating to physician attitudes, education, and clinical decision-making; the biological, psychological, and social considerations in treating patients with …

Bio 2292 : Anatomy And Physiology Ii, Honors, Biological Sciences

Approved Course Proposals

No abstract provided.

Bio 2291 : Anatomy And Physiology I, Honors, Biological Sciences

Approved Course Proposals

No abstract provided.

Targeting The Cellular Redox Environment: A Novel Approach For The Treatment Of Hematopoietic Neoplasms, Dustin W. Carroll

Theses and Dissertations--Toxicology and Cancer Biology

Hematopoietic stem cells (HSCs) that function to maintain the hematopoietic compartment through self-renewal and differentiation capacities, as well as their downstream progeny, are susceptible to transformation resulting in the generation of the leukemic stem cell (LSC). Chief in the factors that control HSC regulation and protection of the HSC compartment is the cellular redox environment. Deregulation of the Hematopoietic Stem/Progenitor Cell (HSPC) redox environment results in loss of HSPC function and exhaustion. The characteristic developments of HSPC exhaustion via exposure to redox stress closely mirror phenotypic traits of hematopoietic malignancies, presenting the HSPC/LSC redox environment as a potential therapeutic target. …

A Novel Role For The Tumor-Suppressor Par-4 In Regulation Of Adipogenesis And Obesity, James Sledziona

Theses and Dissertations--Toxicology and Cancer Biology

Prostate Apoptosis Response-4 (Par-4) is a conserved and ubiquitous tumor-suppressor factor which can selectively induce apoptosis in tumor cells, while leaving normal cells unaffected. While Par-4 is well established as a tumor-suppressor, there have yet been no formal investigations as to whether it has a physiologic role in normal tissues.

Early observations of Par-4 knockout mouse lines yielded that the adult mice displayed significant weight gain and fat accumulation compared to their wild-type counterparts while on a conventional chow diet. Interestingly, obese mouse and human subjects were found to exhibit reduced expression of Par-4 in adipose tissue as well as …

Impact Of Physico-Chemical Properties Of Manufactured Nanomaterials On Plant Uptake And Trophic Transfer, Jieran Li

Theses and Dissertations--Toxicology and Cancer Biology

Large quantities of manufactured nanomaterials (MNM) are released into the environment by human activity each year. The entry of MNM into the terrestrial food webs, which has the potential for far-reaching impacts, begins with the uptake by plant species from the soil. These processes can be affected by MNM physico-chemical properties such as size, chemical composition, surface charge, etc., of which our knowledge is still incomplete. To bridge some of the gaps in our understanding of these processes and, specifically, to determine whether the physico-chemical properties of the MNM are predictive of their behavior in terrestrial food chains, we conducted …

Impact Of Health Insurance And Sociodemographic Characteristics On Survival For Women Diagnosed With Breast Cancer In Kentucky, Pramila Rai

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Introduction Objective of the study was to explore the impact of health insurance and socio-demographic factors on survival for breast cancer patients in Kentucky. Breast cancer is the most prevalent cancer among women in the US. Breast cancer survival is affected by various factors including health insurance, residence, age, race, geographical distance, income.

Methods The data were obtained from Kentucky Cancer Registry and included 47,128 women diagnosed with primary breast cancer between 2000 to 2014. The relationship of health insurance and other socio-demographic factors was analyzed using Cox regression.

ResultsThe overall five-year survival proportion was 0.97, 0.76 and 0.71 …

Implementing The National Diabetes Prevention Program In Mason County, Kentucky, Cassandra Yelton

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The National Diabetes Prevention Program (DPP) is sponsored by the Centers for Disease Control and Prevention (CDC). The program’s goal is to reduce the incidence of diabetes through dietary modification and physical activity. On one hand, the DPP is currently offered by various organizations through the country. On the other hand, the DPP is mostly unavailable in rural areas, especially the Diabetes Belt. The Diabetes Belt is in the eastern Appalachian region of the United States. People who live in this area of the country are more likely to develop diabetes than those who do not. Mason County, Kentucky has …

Microclinic International Social Network Behavioral Health Intervention In Mongolia, Kalli A. Beasley

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Diabetes is a chronic communicable disease that is projected by 2030 to be the seventh leading cause of death worldwide. In Mongolia diabetes and cardiovascular disease are the number one reason for disability-adjusted life years and trends of diabetes is starting to be observed in the poorer populations. Diabetes in countries like Mongolia are extremely costly to treat using insulin, costing $200 USD per month while the average annual income sits only at $1,466.85 USD. Mongolia has a total population of 2,959,000 and half of its population resides in the capital city of Ulaanbaatar. 60% of residents in capital live …

Bronchiolitis In The Bluegrass: Epidemiology, Disease Burden And Resource Utilization At Kentucky Children’S Hospital, Ashwin Krishna

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: Every year Kentucky Children’s Hospital (KCH) admits infants and toddlers with respiratory disease due to viral bronchiolitis. This disease is characterized by viral-induced inflammation and edema of the lower airways. The resulting disease is characterized by increasing mucus production, acute bronchospasm, necrosis of the respiratory epithelium and functional obstructive lung disease. Patients usually present with symptoms consistent with an upper respiratory tract infection, but can progress to marked respiratory distress and ultimately respiratory failure, as well as poor oral intake and dehydration. While Respiratory Syncytial Virus (RSV) is the pathogen classically described cause of viral bronchiolitis, other viruses have …

Modeling The Impact Of 13rs-Hb358: Hpv Vaccination For School Entry In A High-Prevalence State, Stacy Lee Ware

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Prophylactic cancer vaccination presents novel opportunities to improve the health and well-being of populations. Since the approval of a cervical cancer vaccine against human papillomavirus (HPV) in 2006, only three states have passed legislation adding it to their school-entry schedules of required vaccinations. Despite ample evidence of its safety and efficacy, the vaccine remains controversial, and national vaccination rates among both girls and boys remain low. Risk for HPV-related cancers varies by population, and Appalachian Kentucky has among the highest HPV-related morbidity and mortality in the nation. Annual attempts to pass HPV vaccine legislation in Kentucky have so far failed …

Latino Worker Reported Respiratory Symptoms And Stall Bedding On Thoroughbred Horse Farms, Lacy Jinks

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Objective: The purpose of this study is to assess the association between self-reported respiratory symptoms in Latino workers and bedding type used in stalls on thoroughbred horse farms.

Methods: Self-reported community-based questionnaire data from 225 Latino horse farm workers in the southeastern US collected from October 2013-April 2014 were used to investigate associations between upper and lower respiratory symptom prevalence and the type of bedding used in stalls (straw, sawdust, or straw plus wood shavings or sawdust). Analysis was performed by chi-square to compare frequencies of symptoms and demographic and exposure risk factors. Logistic regression was used to adjust …

A Complex Calculus: How Message Format And Processing Route Coordinate To Influence Hpv Vaccination Message Persuasiveness Among Young Adults, Laura Boutemen

Electronic Theses and Dissertations

Human papillomavirus (HPV) infection may lead to cancer and genital warts yet can be prevented by a safe and effective vaccine recommended for individuals up to 26 years old. HPV vaccination rates remain low among college aged adults that represent a catch-up population still eligible to receive the HPV vaccine. This present study is a theory-based investigation employing the Heuristic Systematic Model to explore the effect of message format and processing route on attitude and behavioral intention in the context of HPV vaccination. Undergraduate students aged 17-26 years old (N = 261) from various majors (e.g., STEM, social sciences, humanities) …

Mechanism Design Of A Compact 4-Dof Robotic Needle Guide For Mri-Guided Prostate Intervention, Shihao Zhang

Electronic Theses and Dissertations

In the past several MRI compatible robotic needle guide devices for targeted prostate biopsy have been developed. The large and complex structure have been identified as the major limitations of those devices. Such limitations, in addition to complex steps for device to image registration have prevented widespread implementation of MRI-guided prostate biopsy despite the advantages of MRI compared to TRUS. We have designed a compact MRI-guided robotic intervention with the capability to have angulated insertion to avoid damage to any anatomical feature along the needle path. The system consists of a novel mechanism driven Robotic Needle Guide (RNG). The RNG …

Desistance From Crime Of Serious Juvenile Offenders: Examining The Social And Individual Differences, Lisa Dunkley

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

There is an overrepresentation of youths with disabilities in the juvenile justice system. As a result, each year thousands of juvenile offenders despite of the seriousness of the crimes committed, are released from incarceration with the hopes of living a successful life in society. Despite progressive research on identifying factors associated with desistance, it is still unclear what factors contribute to desistance for serious juvenile offenders and especially those with disabilities. The current study investigated the individual differences (e.g., moral disengagement, motivation to succeed and impulse control) and social factors (e.g., employment, education and maternal warmth) that are important in …

Using The International Classification Of Functioning, Disability, And Health To Predict Participation In Adults With Parkinson’S Disease: The Role Of Positive Psychological Capital, Brad Wayne Mcdaniels

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Participation is generally considered the ultimate rehabilitation outcome and, for individuals with progressive illnesses, elucidating the factors that impact participation is critical. Parkinson’s disease (PD) is a chronic degenerative, neurological condition affecting nearly 1 million people in the United States, making PD the second most prevalent neurodegenerative disorder. PD has a profound negative effect on functioning and activity, but limited literature exists assessing the relationship between PD and community participation. The purpose of this study was to use the World Health Organization (WHO) International Classification of Functioning, Disability, and Health (ICF) as a framework for explaining how PD affects participation. …

A Phenomenological Study Of The Experiences Of Successful Women In Science Fields, Jonathan Hall

Electronic Theses and Dissertations

Girls and women face several forms of gender-based biases and discrimination in the science community. These issues create difficult circumstances for them to develop positive science identities. Since these difficult circumstances exist, science education and sociology researchers have used a deficit model to learn about their experiences, achievements, and attitudes. Understanding the experiences of successful women in science offers insight into how women can navigate the challenges presented by the science community and how science educators can support them. However, research studies that explore the experiences of successful women in science are scant. Therefore, the objective of this study was …

App-Ily Ever After - Self-Presentation And Perception Of Others On The Dating App Tinder, Johnathan Dunlop

Electronic Theses and Dissertations

Location-based real-time dating (LBRTD) apps have become an increasingly common way for people to broaden their social network and meet others for the purposes of dating, friendship, and more. This investigation focused on Tinder, presently the most widely-used LBRTD app. Semi-structured interviews were conducted with twenty-three current and recent Tinder users to gain insight into their self-presentation strategies and impressions of others on the app. The questions concentrated around four major topic areas: use of photos, use of bio text, perception of others, and real or imagined deception. A grounded theory approach was used to frame the data. From this, …

Role Of Single Nucleotide Polymorphisms (Snps) In Ptpn2/22 And Mycobacterium Avium Subspecies Paratuberculosis (Map) In Rheumatoid Arthritis And Crohn's Disease, Robert Sharp

Electronic Theses and Dissertations

Both genetic pre-disposition and potential environmental triggers are shared between Rheumatoid arthritis (RA) and Crohn's disease (CD). We hypothesized that single nucleotide polymorphisms (SNPs) in the negative T-cell regulators Protein Tyrosine Phosphatase Nonreceptor type 2 and 22 (PTPN2/22) lead to a dysregulated immune response as seen in RA and CD. To test the hypothesis, peripheral leukocytes samples from 204 consented subjects were TaqMan genotyped for 9 SNPs in PTPN2/22. The SNPs effect on PTPN2/22 and IFN-y expression was determined using RT-PCR. Blood samples were analyzed for the Mycobacterium avium subspecies paratuberculosis (MAP) IS900 gene by nPCR. T-cell proliferation and response …

Cavity-Coupled Plasmonic Systems For Enhanced Light-Matter Interactions, Abraham Vazquez-Guardado

Electronic Theses and Dissertations

Light-matter interaction is a pivotal effect that involves the synergetic interplay of electromag- netic fields with fundamental particles. In this regard localized surface plasmons (LSP) arise from coherent interaction of the electromagnetic field with the collective oscillation of free electrons in confined sub-wavelength environments. Their most attractive properties are strong field en- hancements at the near field, highly inhomogeneous, peculiar temporal and spatial distributions and unique polarization properties. LSP systems also offer a unique playground for fundamental electromagnetic physics where micro-scale systemic properties can be studied in the macro-scale. These important properties and opportunities are brought up in this work …

Mechanical Behavior Of Posterior All‐Ceramic Hybrid‐Abutment‐ Crowns Versus Hybrid‐Abutments With Separate Crowns—A Laboratory Study, Ahmed Sabet

Dentistry

Objective: The purpose of this laboratory study was to evaluate the fatigue resist‐ ance, fracture resistance and mode of failure of posterior hybrid‐abutment‐crown vs. hybrid‐abutment with separate crown, both bonded to short titanium bases. Materials and Methods: Thirty‐two titanium implants were embedded perpendicu‐ larly in auto‐polymerizing resin. Implant‐supported restorations simulating a maxil‐ lary first premolar were designed and milled using a CAD/CAM system and divided into 2 groups according to material (n = 16): zirconia (Z) and lithium disilicate (L). Each group was subdivided into two subgroups according to design (n = 8): hybrid‐abut‐ ment‐crown (ZS, LS) and hybrid‐abutment with …

Influence Of Dietary Ractopamine And Supranutritional Supplementation Of Vitamin E On Proteome Profile Of Postmortem Beef Longissimus Lumborum Muscle, Hyun Mok Kim

Theses and Dissertations--Animal and Food Sciences

The effects of dietary ingredients on the proteome profile of postmortem beef longissimus lumborum (LL) muscle were evaluated. In the first experiment, the influence of dietary ractopamine on the whole-muscle proteome of beef LL was examined. Five proteins were differentially abundant between ractopamine-fed (RAC) and non-ractopamine fed (CON) groups. The differentially abundant proteins were over-abundant in RAC and were related to muscle structure development (F-actin-capping protein subunit beta-2 and PDZ and LIM domain protein-3), chaperone (heat shock protein beta-1), oxygen transportation (myoglobin), and glycolysis (L-lactate dehydrogenase A chain). These findings indicated that ractopamine influences the abundance of proteins associated with …

Comparing Dairy Farm Performance And Heat Stress Abatment Strategies In The United States Using Summer To Winter Ratios, Jenna M. Guinn

Theses and Dissertations--Animal and Food Sciences

Heat stress abatement is a challenge for producers in the United States, especially in the southern states. Dairy producers could benefit by having a simply metric to measure heat stress abatement strategies with the goal of motivating improvement in heat stress management. Managing heat stress is key to ameliorating the effects on dairy cow performance. A study was performed to explore the use of a heat stress metric called the Summer to Winter performance ratio (S:W ratio), to quantify and compare farm performance variables among regions of the United States. Summer to Winter ratios were closest to 1.0 in the …

Long-Term Effects Of Dietary Copper Source And Level On Performance And Health Of Sows And Piglets, Ning Lu

Theses and Dissertations--Animal and Food Sciences

The objectives of this study were to investigate the long-term effects of feeding increasing supplemental levels (20, 120, or 220 mg/kg) of dietary copper (Cu) as tribasic copper chloride (TBCC) or copper sulfate (CuSO₄) on performance, antioxidant status, nutrient digestibility, and trace mineral deposition of sows and piglets; as well as to assess nursery dietary Cu levels on growth performance and response to immunological challenge in nursery pigs from sows fed either high or low Cu diets. In the long-term sow experiment, sows fed TBCC diets had greater adjusted weaning weight for litter and piglet (P < 0.10), as well as adjusted litter and piglet weight gain (P …