Digital Commons Network^™

The Inherently Flawed Relationship Between Physicians And Pharmaceutical Companies’ Gifts: Tanstaafl*, David P. Paul Iii

Atlantic Marketing Journal

Pharmaceutical companies frequently give practicing physicians and physicians-in-training an assortment of free “gifts,” ranging from pens to stethoscopes to continuing medical education. In an ideal world, these gifts would not compromise, or even seem to compromise, physicians’ decision-making. Unfortunately, as we live in a non-perfect world, this paper examines how physicians have been shown to perceive such gifts, the pharmaceutical companies’ position regarding these gifts, what the theory of gift-giving and gift-receiving tells us about this behavior, and what the future may hold as healthcare becomes more transparent.

Bioproducts From Bacteria: A Synthetic Biology Approach, Andrew Walters, Ron Sims, Charles Miller

Research on Capitol Hill

What can synthetic biology do?

Synthetic biology can solve many of Utah's problems:

1. Health: generate better medicines and treatments

- Insulin, Artemisinin (anti-malaria drug), Cancer

2. Fuel: augment petroleum with biofuels and biogas

3. Electricity: directly generate electricity from waste

4. Food: engineer more nutritious food with higher yields

- Golden rice, Arctic Apples, Corn, Soybeans, Cotton

5. Products: generate necessary products renewably

- Bioplastics, Spider silk, Adhesives, Pigments, Perfumes

Motor Affordance For Grasping A Handrail, D. Mcdannald, M. Mansour, Garrett Rydalch

Research on Capitol Hill

Mere observation of objects around us can potentiate motor action by priming specific areas in the brain. This concept, referred to as the affordance effect, suggests that humans put viewed objects into motor terms automatically. Such automated linking of observations to action offers potential advantages to interact with our environment quickly and efficiently when producing goal-directed movements.

One possible application of this affordance effect includes the rapid balance reactions needed to avoid a fall. In reactive balance control, movements must be extremely fast yet simultaneously appropriate for a given environment (e.g. quickly grasping a nearby handrail to avoid a fall). …

Testing Rearing Diets For A New Invasive Insect Pest In Utah, The Brown Marmorated Stink Bug, James Withers, Loren Linford

Research on Capitol Hill

The brown marmorated stink bug (BMSB), Halyomorpha halys, is an invasive insect from Asia. It has caused millions of dollars in damage to fruit, vegetable, ornamental, and field crops since its arrival in North America, and can be a severe nuisance pest when it congregates on human structures to overwinter. The BMSB caused $37 million of apple crop damage in the Mid-Atlantic Region in 2007 to 2010. To study the insect, effective rearing methods are needed. Previous research (Funayama 2004 & 2006; Medal et al. 2012) showed that carrot, raw peanut and soybean increased rearing efficiency. Recent lab experience …

The Effect Of Gender And Socioeconomic Factors On Reporting Of Concussions Among Ncaa Student-Athletes, Joshua Hansen

Research on Capitol Hill

Concussions are traumatic brain injuries that result from “brain shaking” as a result of transmit force to the head. Concussions result in immediate and transient post-traumatic impairment of neural functions which lead to both psychological and physiological symptoms.

As knowledge of the long-term implications of these injuries grows, concussions are becoming an increasing health concern worldwide. One subset, sports-related concussions, are receiving an increasing amount of attention from scientists and health-care practitioners.

More than 3.8 million sport-related concussions occur annually in the United States alone, and some studies suggest that up to 43% of these go unreported and untreated.

A Collaborative Solution To Harmful Algal Blooms In Utah, Kyle Hillman, Bethany Jensen, Ammon Balle

Research on Capitol Hill

Harmful algal blooms (HABs)…

• affect Utah Lake, Scofield Reservoir, Jordanelle Reservoir, Mantua Lake, and other water bodies throughout Utah
• are toxic to public health, the environment, and the economy

How Pesticide Additives Alter Feeding Behavior And Viral Infections In Honey Bees, Matthew Thompson

Research on Capitol Hill

Honey bees are vital to agriculture; the decline of honey bee populations in Utah and worldwide is concerning. Several factors can reduce honey bee health and when they interact can increase in magnitude (Fig. 1). We are investigating the interactions of a pesticide ingredient, organosilicone surfactant (OSS), and viral pathogens.

Goals

• Determine if OSS exposure alters honey bee feeding behavior.
• Determine if OSS synergizes with and increases the negative impact of viruses on honey bees.

Does Requiring Participation In Research Have A Positive Effect On Students’ Perception Of Undergraduate Research?, Mikayla Austin

Research on Capitol Hill

Undergraduate research is not only beneficial to the university and community for all the new ideas it brings to light, but plays an important role in student development.

Studies have shown that students who are involved in research as undergraduates are proficient in:

• Critical thinking
• Communication
• Confidence
• Problem solving

There have been many studies conducted on the best ways to get students involved in research in order to gain these benefits, most of which are based around increasing awareness.

My research is focused on the impact of bringing research into the classroom and requiring students to participate. Will this increase …

Transplanting A Bacterial Immune System: Determining The Function Of A Novel Crispr System, Riannon Smith, Melena Garrett

Research on Capitol Hill

CRISPR (Clusters of Regularly Interspaced Short Palindromic Repeats) loci and cas (CRISPR-associated) genes provide adaptive immunity (see panel below) in bacteria and have recently been repurposed for genome editing.

Systems are structurally and functionally diverse.

• 2 classes, 6 types, 33 subtypes
• Very few have been studied experimentally
• None of the Type IV systems have been characterized

An Examination Of The Prevalence Of Intimate Partner Violence Training In U.S. Medical School Curriculum, Tyson Lumbreras

Research on Capitol Hill

• 1 in 3 women and 1 in 4 men living in the United States experience some form of Intimate Partner Violence or IPV (Black, et al. 2011).
• Although there is some research that examines the role health care professionals play in identifying IPV (Richardson, et al. 2002), there is less research on how effectively they are trained to handle it.
• My research will determine whether medical students are receiving adequate IPV training through comprehensive data on the quality of IPV training across U.S. schools.

Diginol: A Joule-Heated Binary-Partitioned Nitinol Actuator Design And Testing Methodology, Martin Dawson Holland, Douglas H. Ross

Early Career Technical Journal (ECTJ)

Section 5: Mechanics; pp. 142-149

Colon Epithelial Microrna Network In Fatty Liver, Paule V. Joseph, Sarah K. Abey, Dan Wang, Nicolaas H. Fourie, Natnael D. Kenea, Tatyana G. Vishnyakova, Jeffrey M. Robinson, Kristen R. Weaver-Toedtman Phd, Acnp, Anp, Christina M. Boulineaux, Hannah R. Davidson, Leeanne B. Sherwin, Onyinyechi Ozoji, Ana F. Diallo, Paul A. Smyser, Amy P. Patterson, Wendy A. Henderson

Publications

Background & Aims. Intestinal barrier alterations are associated with fatty liver (FL) and metabolic syndrome (MetS), but microRNA (miR) signaling pathways in MetS-FL pathogenesis remain unclear. This study investigates an epithelial-focused miR network in colorectal cell models based on the previously reported MetS-FL miR trio of hsa-miR-142-3p, hsa-miR-18b, and hsa-miR-890. Methods. Each miR mimic construct of MetS-FL miR trio was transfected into human colorectal cells, CRL-1790 or Caco-2. Global miRNome changes posttransfection were profiled (nCounter® Human v3 miRNA, NanoString Technologies). Changes in barrier (transepithelial electrical resistance, TEER) and epithelial cell junction structure (Occludin and Zona Occludens-1/ZO-1 immunofluorescence staining-confocal microscopy) were …

On-Farm Utilization Of Precision Dairy Monitoring: Usefulness, Accuracy, And Affordability, Elizabeth A. Eckelkamp

Theses and Dissertations--Animal and Food Sciences

Precision dairy monitoring is used to supplement or replace human observation of dairy cattle. This study examined the value dairy producers placed on disease alerts generated from a precision dairy monitoring technology. A secondary objective was calculating the accuracy of technology-generated disease alerts compared against observed disease events. A final objective was determining the economic viability of investing in a precision dairy monitoring technology for detecting estrus and diseases.

A year-long observational study was conducted on four Kentucky dairy farms. All lactating dairy cows were equipped with a neck and leg tri-axial accelerometer. Technologies measured eating time, lying time, standing …

An Evaluation Of Physiological And Behavioral Indicators Of Postpartum Diseases And Heat Stress In Dairy Cows, Amanda Renee Lee

Theses and Dissertations--Animal and Food Sciences

Precision dairy monitoring technologies can be used to monitor changes in physiology and behavior associated with transition period postpartum diseases and heat stress. Research Objective One was to evaluate how traditional visual examination, body condition, and locomotion with and without blood, milk, and urine variables and precision dairy monitoring technologies determine variable association with hyperketonemia, metritis, mastitis, hypocalcemia and retained placenta,. This was accomplished by monitoring cows 2 weeks before calving to 3 weeks after calving for any postpartum diseases using daily visual examination and automatically detected variables including activity, milk yield, milk components, lying behavior, feeding behavior, rumination time, …

The Effects Of Housing On Dairy Cow Comfort, Immune Function, Stress, Productivity, And Milk Quality, Matthew Richard Borchers

Theses and Dissertations--Animal and Food Sciences

Mastitis and milk quality affect every dairy farmer across the globe. Sand bedded freestalls are the industry standard for cow comfort, welfare, and the control of environmental mastitis. Compost bedded packs may be a viable alternative to the sand bedded freestall.

Compost bedded packs are maintained at a consistent level of moisture, nutrients, and aeration to favor compost microorganisms. Greater bacteria counts in bedding have traditionally been associated with increased mastitis rates and mastitis pathogens can be found in the pack and on the teats of cattle housed in even well managed compost bedded pack barns. In spite of this, …

Whole-Body Protein Metabolism In Mature And Growing Horses Receiving Predominantly Forage Diets, Sophie A. Stratton

Theses and Dissertations--Animal and Food Sciences

There has been limited investigation as to whether a predominantly forage-based diet can provide adequate amounts of limiting amino acids (AA) to horses. The first objective was to determine if AA supplementation of AA believed to be limiting to protein synthesis in forage-based diets would affect measures of whole-body protein metabolism in sedentary mature horses. The effect of forage type (timothy or alfalfa) and AA supplementation (lysine, threonine or histidine) on plasma urea nitrogen (PUN) and AA concentrations and measures of whole-body phenylalanine kinetics were evaluated. There was no effect of either forage type or AA supplement on rates of …

Evolution Of Occupational Therapy Practice: Life History Of Sue Morrison, Ashton Hudspeth, Colton Peltier

Oral History Student Papers

This qualitative study gathered information regarding the evolution of occupational therapy in North Dakota and Wyoming. Its purpose was to provide a view of what practice looked like from the beginning of Sue Morrison’s occupational therapy career until now by uncovering her life history. She has played an influential role in pediatric occupational therapy in Wyoming. The goal of this study was to provide more knowledge for current occupational therapists about the history of occupational therapy and how it has changed over time. This was done by interviewing individuals who have impacted the occupational therapy profession in the states of …

Wireless Power Transfer For Biomedical Applications, Reem Shadid

Theses and Dissertations

In this research wireless power transfer using near-field inductive coupling is studied and investigated. The focus is on delivering power to implantable biomedical devices.

The objective of this research is to optimize the size and performance of the implanted wireless biomedical sensors by: (1) proposing a hybrid multiband communication system for implantable devices that combines wireless communication link and power transfer, and (2) optimizing the wireless power delivery system. Wireless data and power links are necessary for many implanted biomedical devices such as biosensors, neural recording and stimulation devices, and drug delivery and monitoring systems.

The contributions from this research …

Evaluation Of Movements And Habitat Use Of Suburban Striped Skunks (Mephitis Mephitis) In The Northern Great Plains To Inform Rabies Management, Anna Schneider

Theses and Dissertations

Few studies have investigated the ecology of urban striped skunks (Mephitis mephitis) despite their role as a primary rabies vector species paired with an ability to thrive in these landscapes. Our aim was to obtain baseline ecological information with an emphasis on spatial ecology of urban striped skunks in the Northern Great Plains region that is missing in the literature. This information, such as home range, nightly movements, habitat selection, and denning behavior is important for informing rabies management decisions such as the placement of oral rabies vaccine (ORV) baits. We used radio telemetry equipment to track 22 (4M, 18 …

Characterization Of Infectious Isolates Of Borrelia Burgdorferi In North Dakota, Bb0399 And Bbb28 In B. Burgdorferi, And Borrelia Miyamotoi In Vitro And In Vivo, Brandee Lynn Stone

Theses and Dissertations

The Borrelia burgdorferi sensu lato (s.l.) complex contains species carried by hard-shell ticks (Ixodes spp.) and causing Lyme disease and related non-pathogenic species. Relapsing fever Borrelia include both tick-borne (soft-shell, Ornithodoros spp.) and louse-borne species knowns to cause relapsing fever. A subgroup includes relapsing fever spirochetes carried by hard-shell ticks, including B. miyamotoi, an emerging pathogen. Despite bordering high-risk counties in Minnesota, little attention has been given to Lyme disease, B. burgdorferi, I. scapularis, or reservoirs in eastern North Dakota. Reports of B. burgdorferi and I. scapularis in North Dakota, however, prompted a more detailed examination. Through trapping Peromyscus and …

The Relationship Between The Digit Ratio (2d:4d) And Explosive Muscular Strength In College Football Players, Jacob Disterhaupt

Theses and Dissertations

Prenatal testosterone, reflected by digit ratio (2D:4D), is thought to benefit the cardiovascular and musculoskeletal systems and has been shown to benefit long-duration exercise performance, but little is known about the relationship between 2D:4D and short-duration exercise performance (e.g., explosive muscular strength). This study describes the relationship between 2D:4D and lower-body explosive strength, a key factor in successful sports performance, in college athletes. Sixty-one Division I American Football players from a Midwestern U.S. university had their 2D:4D measured digitally and squat jump performance measured using force-platform jumping mechanography. In addition to the primary outcome of jump height, secondary outcomes depicting …

Origin And Preservation Of Organic-Rich Zones And Kukersite Beds Of The Red River Formation (Upper Ordovician), Williston Basin, North Dakota, Spencer Wheeling

Theses and Dissertations

The Red River Formation is North Dakota’s third most productive hydrocarbon unit. The unit has been interpreted to be self-sourced, but the locations of the source beds has not been thoroughly investigated within the North Dakota portion of the Williston Basin. Using the most current available data, this study investigated the source beds of the Red River Formation. This present study agrees with past studies that there are two source bed types; the first type being a higher organic-rich, thin kukersite bed and the second being a less organic-rich, thicker organic zone. Both types of source beds commonly occur as …

Morphological And Genetic Analysis Of Embryo Specific Mutants In Maize, Dale Cletus Brunelle

Theses and Dissertations

The maize zygote normally develops over approximately 45-days into a mature embryo comprised of five or six leaf primordia and several root primordia. The developing embryo passes through the proembryo, transition, coleoptilar and stage 1 (first leaf primordium) morphogenetic stages followed by the iterative formation of additional leaf primordia during stages 2 through 6 according to Abbe and Stein (1954). Using ethyl methanesulfonate (EMS) treatment of maize pollen from W22 inbreed we have produced lethal embryo specific (emb) mutants that have no obvious effects on endosperm development except for some reduction in kernel size in some cases. Thirteen emb mutants …

Exploring Student Perspectives On Elementary To Middle School Transition Practices, Erin Spies

Theses and Dissertations

Characteristics of effective transition programs include (a) providing realistic experiences of middle school expectations for incoming students, (b) frequent communication with students, parents, and staff, and (c) extensive and ongoing planning, assessment, and redesign of the transition program. While these effective components of a transition program have been recommended based on research, student reflection on essential elements have not been included. The purpose of this study was to use phenomenology research methods to identify components of middle school transition programs from the perspective of middle school students. The study analyzed current transitional practices and their alignment with Schlossberg’s Transition Theory …

Examining Cultural Identification And Alcohol Use Among College Students, Lynn Martell

Theses and Dissertations

Previous research has found American Indians (AI) to demonstrate higher levels of alcohol use than Caucasians (CA); however, recent research has found that AI may be drinking at similar or lower rates than CA. Cultural identification (i.e., degree to which an individual associate with, and represents themselves as a member of a specific cultural group) may be a factor contributing to the level of alcohol use among AI. The current study examined cultural identification and alcohol use among University of North Dakota (UND) AI (n=56) and CA (n=88) college students. Results indicated non-significant differences in alcohol use between cultural identification …

The Role Of A Principal In Establishing And Maintaining Positive Behavioral Interventions And Supports (Pbis): An Ethnographic Case Study, Angela Wanzek

Theses and Dissertations

An ethnographic case study was used to examine roles of a principal in implementing and maintaining positive behavioral interventions and supports (PBIS) in one North Dakota elementary school. Observations, school documents, and semi-structured interviews were analyzed to identify the role of a principal. Skinner’s reinforcement theory and Bronfenbrenner’s bioecological systems theory served as

theoretical frameworks.

Research indicates a trend in the increase of PBIS in schools across the country. A

need remains to identify the role of elementary principals utilizing PBIS in North Dakota

elementary schools. Certified and classified staff were interviewed to examine their

perspectives on the role of …

Differential Gene Expression Of Muscle-Invasive Bladder Cancer Marker Genes In A Model Of Arsenite And Cadmium Induced Bladder Cancer, Danyelle Beth Osowski

Theses and Dissertations

Urinary carcinoma is one of the most prevalent cancers across the United States and is among the leading cause of cancer related morbidities. With muscle-invasive urinary carcinoma having only 15% survival at stage T4, diagnostic tools of this type of cancer is necessary. This work sought to characterize a model of urothelial carcinoma into a specific muscle-invasive bladder cancer subtype, which has important implications in for prognosis, development of targeted therapeutic agents, and disease management. Our laboratory has developed an immortalized uroepithelial cell line, UROtsa, which can be malignantly transformed by arsenite (As+3) and Cd2+ and has been shown to …

The Problem Of The West[Ern], Kiley Duhn

Compass: An Undergraduate Journal of American Political Ideas

Three great Western films—Stagecoach, The Man Who Shot Liberty Valance, and the contemporary No Country for Old Men—delve deep into the American psyche and make a broad claim that the American way of mixing freedom and rule is inherently flawed.

Author information: Kiley Duhn is a Business Economics and Accountancy double major and Political Science minor at Miami University in Oxford, Ohio. After graduating in the Class of 2019, she plans to pursue a career in tax consulting at a public accounting firm.

Neuroprotective And Anti-Inflammatory Effects Of Rhus Coriaria Extract In A Mouse Model Of Ischemic Optic Neuropathy, Saba Khalilpour, Ghazaleh Behnammanesh, Fouad Suede, Mohammed O. Ezzat, Jayadhisan Muniandy, Yasser Tabana, Mohamed B. K. Ahamed, Ali Tamayol, Amin Malik Shah Majid, Enrico Sangiovanni, Mario Dell'agli, Aman Shah Majid

Department of Mechanical and Materials Engineering: Faculty Publications

Modulating oxidative stresses and inflammation can potentially prevent or alleviate the pathological conditions of diseases associated with the nervous system, including ischemic optic neuropathy. In this study we evaluated the anti-neuroinflammatory and neuroprotective activities of Rhus coriaria (R. coriaria) extract in vivo. The half maximal inhibitory concentration (IC₅₀) for DPPH, ABTS and B-carotene were 6.79 ± 0.009 µg/mL, 10.94 ± 0.09 µg/mL, and 6.25 ± 0.06 µg/mL, respectively. Retinal ischemia was induced by optic nerve crush injury in albino Balb/c mice. The anti-inflammatory activity of ethanolic extract of R. coriaria (ERC) and linoleic acid (LA) on …

The Extended Evolutionary Synthesis Facilitates Evolutionary Models Of Culture Change, Cameron M. Smith, Liane Gabora, William Gardner-O’Kearney

Anthropology Faculty Publications and Presentations

The Extended Evolutionary Synthesis (EES) is beginning to fulfill the whole promise of Darwinian insight through its extension of evolutionary understanding from the biological domain to include cultural information evolution. Several decades of important foundation-laying work took a social Darwinist approach and exhibited ecologically-deterministic elements. This is not the case for more recent developments to the evolutionary study of culture, which emphasize non-Darwinian processes such as self-organization, potentiality, and epigenetic change.