Digital Commons Network^™

Genetically Enhancing The Expression Of Chemokine Domain Of Cx3cl1 Fails To Prevent Tau Pathology In Mouse Models Of Tauopathy, Shane M. Bemiller, Nicole M. Maphis, Shane V. Formica, Gina N. Wilson, Crystal M. Miller, Guixiang Xu, Olga N. Kokiko-Cochran, Ki-Wook Kim, Steffen Jung, Judy L. Cannon, Samuel D. Crish, Astrid E. Cardona, Bruce T. Lamb, Kiran Bhaskar

Open Access Publications

No abstract provided.

Blood Manufacturing Methods Affect Red Blood Cell Product Characteristics And Immunomodulatory Activity, Ruqayyah J. Almizraq, Philip J. Norris, Heather Inglis, Somaang Menocha, Mathijs R. Wirtz, Nicole Juffermans, Suchitra Pandey, Philip C. Spinella, Jason P. Acker, Jennifer A. Muszynski

Open Access Publications

No abstract provided.

Novel Patient-Centered Approach To Facilitate Same-Day Discharge In Patients Undergoing Elective Percutaneous Coronary Intervention, Amit P. Amin, Patricia Crimmins-Reda, Samantha Miller, Brandon Rahn, Mary Caruso, Andrew Pierce, Brandy Dennis, Marissa Pendegraft, Katrine Sorensen, Howard I. Kurz, John M. Lasala, Alan Zajarias, Richard G. Bach, Hemant Kulkarni, Jasvindar Singh

Open Access Publications

No abstract provided.

Methylation-Based Enrichment Facilitates Low-Cost, Noninvasive Genomic Scale Sequencing Of Populations From Feces, Kenneth L. Chiou, Christina M. Bergey

Open Access Publications

No abstract provided.

Bioreducible Polymer Micelles Based On Acid-Degradable Poly(Ethylene Glycol)-Poly(Amino Ketal) Enhance The Stromal Cell-Derived Factor-1Α Gene Transfection Efficacy And Therapeutic Angiogenesis Of Human Adipose-Derived Stem Cells, Tae-Jin Lee, Min Suk Shim, Taekyung Yu, Kyunghee Choi, Dong-Ik Kim, Soo-Hong Lee, Suk Ho Bhang

Open Access Publications

No abstract provided.

A Knock-In Tristetraprolin (Ttp) Zinc Finger Point Mutation In Mice: Comparison With Complete Ttp Deficiency, Wi S. Lai, Deborah J. Stumpo, Lianqun Qiu, Roberta Faccio, Perry J. Blackshear

Open Access Publications

No abstract provided.

Tidal And Diel Orchestration Of Behaviour And Gene Expression In An Intertidal Mollusc, Y. Schnytzer, N. Simon-Blecher, J. Li, H. Waldman Ben-Asher, M. Salmon-Divon, Y. Achituv, M. E. Hughes, O. Levy

Open Access Publications

No abstract provided.

Cell Circuits Between B Cell Progenitors And Il-7+ Mesenchymal Progenitor Cells Control B Cell Development, Chris Fistonich, Sandra Zehentmeier, Jeffrey J. Bednarski, Runfeng Miao, Hilde Schjerven, Barry P Sleckman, João P Pereira

Open Access Publications

B cell progenitors require paracrine signals such as interleukin-7 (IL-7) provided by bone marrow stromal cells for proliferation and survival. Yet, how B cells regulate access to these signals in vivo remains unclear. Here we show that proB and IL-7

Measurement & Analysis Of The Temporal Discrimination Threshold Applied To Cervical Dystonia, Rebecca B. Beck, Eavan M. Mcgovern, John Butler, Dorina Birsanu, Brendan Quinlivan, Ines Beiser, Shrut Narasimham, Sean O'Riordan, Michael Hutchinson, Richard B. Reilly

Other resources

The temporal discrimination threshold (TDT) is the shortest time interval at which an observer can discriminate two sequential stimuli as being asynchronous (typically 30-50 ms). It has been shown to be abnormal (prolonged) in neurological disorders, including cervical dystonia, a phenotype of adult onset idiopathic isolated focal dystonia. The TDT is a quantitative measure of the ability to perceive rapid changes in the environment and is considered indicative of the behavior of the visual neurons in the superior colliculus, a key node in covert attentional orienting. This article sets out methods for measuring the TDT (including two hardware options and …

Researchnews, 2018, Dit Public Affairs Office

Issues

No abstract provided.

Influenza Infection Directly Alters Innate Il-23 And Il-12p70 And Subsequent Il-17a And Ifn-Γ Responses To Pneumococcus In Vitro In Human Monocytes, Sinead T. Loughran, Patrick A. Power, Paula T. Maguire, Samantha L. Mcquaid, Paul J. Buchanan, Ingileif Jonsdottir, Robert W. Newman, Ruth Harvey, Patricia A. Johnson

Articles

It is well accepted that influenza A virus predisposes individuals to often more severe super-infections with Streptococcus pneumonia. However, the mechanisms that lead to this synergy are not clearly understood. Recent data suggests that competent Th17 immunity is crucial to clearance and protection from invasive pneumococcal disease of the lung. We demonstrate that early influenza infection significantly reduced levels of pneumococcus driven IL-12p70, IL-23 and IL-27 in human monocytes with significant impairment of IL-17A and IFN-γ in HKSP-treated allogeneic mixed lymphocyte cultures. We also provide evidence to suggest that the hemagglutinin component of the virus is at least partially responsible …

The Role Of Bpifa1 In Upper Airway Microbial Infections And Correlated Diseases, Yung-An Tsou, Min-Che Tung, Katherine A. Alexander, Wen-Dien Chang, Ming-Hsui Tsai, Hsiao-Ling Chen, Chuan-Mu Chen

Open Access Publications

No abstract provided.

Plerixafor Plus Granulocyte Colony-Stimulating Factor For Patients With Non-Hodgkin Lymphoma And Multiple Myeloma: Long-Term Follow-Up Report, Ivana N. Micallef, Patrick J. Stiff, Auayporn P. Nademanee, Richard T. Maziarz, Mitchell E. Horwitz, Edward A. Stadtmauer, Jonathan L. Kaufman, John M. Mccarty, Rita Vargo, Peter D. Cheverton, Martin Struijs, Brian Bolwell, John F. Dipersio

Open Access Publications

No abstract provided.

Genome-Wide Mega-Analysis Identifies 16 Loci And Highlights Diverse Biological Mechanisms In The Common Epilepsies, Liu Lin Thio, Judith Weisenberg

Open Access Publications

No abstract provided.

Germline Variation At 8q24 And Prostate Cancer Risk In Men Of European Ancestry, Gerald Andriole, Aleksandra Klim, Bettina F. Drake

Open Access Publications

No abstract provided.

Lj-1888, A Selective Antagonist For The A3 Adenosine Receptor, Ameliorates The Development Of Atherosclerosis And Hypercholesterolemia In Apolipoprotein E Knock-Out Mice, Jong-Gil Park, Se-Jin Jeong, Jinha Yu, Gyudong Kim, Lak Shin Jeong, Goo Taeg Oh

Open Access Publications

No abstract provided.

A Method For Identifying Mouse Pancreatic Ducts, Chiemi Nakajima, Kenji Kamimoto, Katsuhiro Miyajima, Masahito Matsumoto, Yasushi Okazaki, Kazuo Kobayashi-Hattori, Makoto Shimizu, Takumi Yamane, Yuichi Oishi, Ken Iwatsuki

Open Access Publications

No abstract provided.

Proton Spin-Lattice Relaxation In Organic Molecular Solids: Polymorphism And The Dependence On Sample Preparation, Peter A. Beckmann, Jamie Ford, William Paul Malachowski, Andrew R. Mcghie, Curtis E. Moore, Arnold L. Rheingold, Gilbert J. Sloan, Steven T. Szewczyk

Physics Faculty Research and Scholarship

We report solid‐state nuclear magnetic resonance 1H spin‐lattice relaxation, single‐crystal X‐ray diffraction, powder X‐ray diffraction, field emission scanning electron microscopy, and differential scanning calorimetry in solid samples of 2‐ethylanthracene (EA) and 2‐ethylanthraquinone (EAQ) that have been physically purified in different ways from the same commercial starting compounds. The solid‐state 1H spin‐lattice relaxation is always non‐exponential at high temperatures as expected when CH3 rotation is responsible for the relaxation. The 1H spin‐lattice relaxation experiments are very sensitive to the “several‐molecule” (clusters) structure of these van der Waals molecular solids. In the three differently prepared samples of EAQ, the relaxation also becomes …

Design Of Cloud Based Robots Using Big Data Analytics And Neuromorphic Computing, Ashwin Satyanarayana, Janusz Kusyk, Yu-Wen Chen

Publications and Research

Understanding the brain is perhaps one of the greatest challenges facing twenty-first century science. While a traditional computer excels in precision and unbiased logic, its abilities to interact socially lags behind those of biological neural systems. Recent technologies, such as neuromorphic engineering, cloud infrastructure, and big data analytics, have emerged that can narrow the gap between traditional robots and human intelligence. Neuromorphic robotics mimicking brain functions can contribute in developing intelligent machines capable of learning and making autonomous decisions. Cloud-based robotics take advantage of remote resources for parallel computation and sharing large amounts of information while benefiting from analysis of …

Foreword By Guest Editors Maa 2018 Volume 18 Issue 4, Frank Prendergast, A. César González-García, Gary Wells, Juan Antonio Belmonte

Conference Papers

MAA SPECIAL ISSUE VOL 18 ISSUE 4:

Sixty-three (63) Selected (peer reviewed) Papers of the INSAP X – Oxford XI – SEAC 25th Joint Conference ‘ROAD TO THE STARS’, held in Santiago de Compostela, Spain, 18th–22nd September 2017

Mediterranean Archaeology and Archaeometry (MAA) is an Open Access Journal published since 2001 by The University of the Aegean, Department of Mediterranean Studies, Rhodes, Greece.

It covers the dual nature of archaeology and cultural heritage with science which includes, amongst others, natural science applied to archaeology (physics, chemistry, biology, geology, geophysics, astronomy), archaeology, ancient history, cultural sustainability, astronomy in culture, physical anthropology, …

The Madness Of Insane Delusions, Kevin Bennardo

Faculty Publications

This Article shares two ideas for reform of the law surrounding testators' expressed preferences and the doctrine of insane delusions.

First, the doctrine of insane delusions should not be applied to devises that seek to advance beliefs, ideas, or viewpoints. There is just too great of a risk that judges and juries will strike down such devises when the testator’s viewpoints diverge from their own.

Second, the time may have come to admit that the law of wills is not as committed to the principle of testamentary freedom as it is often espoused to be. The literature is rife with …

Sexual Orientation And Gender Identity Discrimination, Holning S. Lau

Faculty Publications

No abstract provided.

Editing Nature: Reconceptualizing Biotechnology Governance, Jonas J. Monast

Faculty Publications

No abstract provided.

Exercise Science Pre-Physical Therapy, Ksr

Program Revisions/Additions

No abstract provided.

Palladium-Catalyzed Carbonyl Allylation Reactions Using Tin Chloride: A Mini-Review, Armando M. Guidote Jr, Mikael John A. Baltazar, Roy Kristian C. Yanela, Noriyuki Suzuki

Chemistry Faculty Publications

The treatment of allylic alcohols as synthons of carbanions for carbonyl allylation reactions in the presence of a Pd-SnCl2 system has been one of the most interesting and most useful developments demonstrated by Yoshiro Masuyama and co-workers in the field of organic synthesis. The reaction makes use of palladium as an effective catalyst and tin (II) chloride as a low-valent reducing agent which also effectively transforms the allylic group to a nucleophilic group. The organic, as well as organometallic, chemistry of how the transformations occur and how the metals take part in the reaction is of great interest. These could …

Educational Attainment, Teaching Experience, Professional Development And Self-Efficacy As Predictors Of Chemistry Content Knowledge: Implication For The Development Of A National Promotion Examination, Jina Denise R. Galiza, Rhodora F. Nicdao, Armando M. Guidote Jr

Chemistry Faculty Publications

This study examined teachers’ content knowledge (CK) in chemistry and its relationship to teachers’ chemistry background, teaching experience, involvement in professional development and self-efficacy It was further investigated which variables predicted the level of content knowledge (CK) of one hundred public secondary chemistry teachers. The data shows that the majority of science teachers have low level of CK in Chemistry. Teaching experience, professional development, chemistry background, and self-efficacy were significantly related to the CK of teachers. Teachers' professional development and self-efficacy predicted the CK of teachers.

High Sensitivity Optical Fiber Sensors For Simultaneous Measurement Of Methanol And Ethanol, Dejun Liu, Rahul Kumarb, Fangfang Wei, Wei Han, Arun Kumar Mallik, Jinhui Yuanc, Shengpeng Wan, Xingdao He, Zhe Kange, Feng Li, Chongxiu Yu, Gerald Farrell, Yuliya Semenova, Qiang Wu

Articles

High sensitivity volatile organic compounds (VOCs) sensors based on a tapered small core single mode fiber (TSCSMF) and a microfiber coupler (MFC) are reported. The TSCSMF had a waist diameter of ~5.1 μm and the MFC had a waist diameter of ~1.9 μm each and both were fabricated using a customized microheater brushing technique. Silica based materials containing immobilized Nile red prepared by sol-gel method with two different recipes (recipe I and recipe II) are investigated. Initially recipe I based coating materials were applied to the surfaces of the TSCSMF and MFC. The experimental results show that the sensor based …

Diagnosis Of Advanced Skin Cancer Using Infrared Spectral Histopathology, Cassio A. Lima, Luciana Correa, Hugh Byrne, Denise M. Zezell

Conference papers

Abstract: In this study, we investigated the feasibility of Infrared Spectral Histopathology to diagnose invasive squamous cell carcinoma using hematoxylin and eosin stained tissue placed on conventional glass slides, as used in the pathologist workflow.

High-Sensitivity Salinity Sensor Based On Optical Microfiber Coil Resonator, Y. Yin, S. Li, J. Ren, Gerald Farrell, E. Lewis, Pengfei Wang

Articles

In recent years, salinity sensing has attracted much attention in potential areas ranging from marine monitoring, marine circulation, marine climate and environment protection in oceanography [1–4]. Generally, traditional methods of salinity measurement have been based on electronic methods (electrochemical) to detect the existence of chlorine ions of the seawater [5,6]. However, this method is affected greatly from the harsh environment, such as high corrosivity, extreme temperature and strong electromagnetic interference and is not used widely in micro scale due to its large size and complex structure. Electrochemical sensors are also prone to cross-sensitivity from and can even be damaged by …

Structure-Property Relationships For A Series Of Ruthenium(Ii) Polypyridyl Complexes Elucidated Through Raman Spectroscopy, Luke O'Neill, Laura Perdisatt, Christine O'Connor

Articles

A series of ruthenium polypyridyl complexes were studied using Raman spectroscopy supported by UV/Vis absorption, luminescence spectroscopy, and luminescence lifetime determination by time-correlated single photon counting (TCSPC). -e complexes were characterised to determine the influence of the variation of the conjugation across the main polypyridyl ligand. -e systematic and sequential variation of the main polypyridyl ligand, 2-(4-formylphenyl)imidazo[4,5-f][1,10]phenanthroline (FPIP), 2-(4-cyanophenyl)imidazo[4,5-f][1,10]phenanthroline (CPIP), 2-(4-bromophenyl)imidazo[4,5-f][1,10]phenanthroline (BPIP), and 2-(4-nitrophenyl)imidazo[4,5-f][1,10]phenanthroline (NPIP) ligands, allowed the monitoring of very small changes in the ligands electronic nature. Complexes containing a systematic variation of the position (para, meta, and ortho) of the nitrile terminal group on the ligand (the para …