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La Voz Winter 2018, El Instituto

La Voz

In this issue:

• Hurricane María
• Metanoia events
• Speakers: Sir Hilary Beckles; Ailyn Morera
• Mead Lecture
• PRCAP: Puerto Rico Citizenship Archives Project
• Tinker Field Research
• Spotlight: Joseline Tlacomulco
• Poetry: Nicole Delgado

Perspectives Volume 6: Number 1, Winter-Spring 2018, College Of Health Care Sciences

Perspectives

No abstract provided.

Unm Hsc Annual Education Day Agenda, Office For Medical Educator Development

HSC Education Days

No abstract provided.

Examining The Variability In General Education Placements For Students With Intellectual Disability, Meghan Cosier, Julia M. White, Qiu Wang

Education Faculty Articles and Research

Despite the overwhelming body of research suggesting that students with intellectual disability benefit from access to general education placements, students with intellectual disability continue to be educated primarily in segregated settings. Furthermore, the percentage of students with intellectual disability included in general education classrooms varies greatly among and within states across the United States. In an effort to explore such variability in New York State, we examined trends in general education placement rates of students with intellectual disability across districts and possible predictors of placement in regular classes. Results suggest that although descriptive patterns of placement exist, a more definitive …

The Drug Repurposing Ecosystem: Intellectual Property Incentives, Market Exclusivity, And The Future Of "New" Medicines, Sam F. Halabi

Faculty Publications

The pharmaceutical industry is in a state of fundamental transition. New drug approvals have slowed, patents on blockbuster drugs are expiring, and costs associated with developing new drugs are escalating and yielding fewer viable drug candidates. As a result, pharmaceutical firms have turned to a number of alternative strategies for growth. One of these strategies is "drug repurposing"-finding new ways to deploy approved drugs or abandoned clinical candidates in new disease areas. Despite the efficiency advantages of repurposing drugs, there is broad agreement that there is insufficient repurposing activity because of numerous intellectual property protection and market failures. This Article …

Response And Resistance To Paradox-Breaking Braf Inhibitor In Melanomas, Edward J. Hartsough, Curtis H. Kugel, Michael J. Vido, Adam C. Berger, Timothy J. Purwin, Allison F. Goldberg, Michael A. Davies, Matthew J. Schiewer, Karen E. Knudsen, Gideon Bollag, Andrew E. Aplin

Department of Cancer Biology Faculty Papers

FDA-approved BRAF inhibitors produce high response rates and improve overall survival in patients with BRAF V600E/K-mutant melanoma, but are linked to pathologies associated with paradoxical ERK1/2 activation in wild-type BRAF cells. To overcome this limitation, a next-generation paradox-breaking RAF inhibitor (PLX8394) has been designed. Here, we show that by using a quantitative reporter assay, PLX8394 rapidly suppressed ERK1/2 reporter activity and growth of mutant BRAF melanoma xenografts. Ex vivo treatment of xenografts and use of a patient-derived explant system (PDeX) revealed that PLX8394 suppressed ERK1/2 signaling and elicited apoptosis more effectively than the FDA-approved BRAF inhibitor, vemurafenib. Furthermore, PLX8394 was …

The International Right To Health Care: A Legal And Moral Defense, Michael Da Silva

Michigan Journal of International Law

In the following, I outline the case against the international right to health care and explain why recognition of such a right is still necessary. The argument is explicitly limited to international human rights law and is primarily descriptive in nature, but I go on to explain the moral reasons to accept this account. Both the positive law and moral reasoning could be used in other health rights debates, but I do not attempt to make such claims here.

The structure of my work is as follows. I first outline three problems with recognizing an international right to health care. …

Trimethyltin-Induced Cerebellar Damage On Adult Male Wistar Rats. Trimetil Estaño Induce Daño Cerebral En Ratas Machos Adultas Wistar., M. S. Ajao, A. Okesina, Martin C. Nwadiugwu

Interdisciplinary Informatics Faculty Publications

Abstract: This research work was done to investigate the acute toxicological effect of trimethyltin chloride on the cerebellum of Wistar rat. Ten adult male Wistar rats were used for the study. The animals were grouped into two: Group A and B, with five adult male Wistar rats in each group. Group A serves as the trimethyltin (TMT) group, while group B serves as the normal saline (NS) group. 3mg/kg of trimethyltin chloride was administered to animals in the TMT group, while 1.0mls of normal saline was administered to the animals in the NS group via intraperitoneal route for 3 …

Evolutionary History Of Plant Hosts And Fungal Symbionts Predicts The Strength Of Mycorrhizal Mutualism, Jason D. Hoeksema, James D. Beaver, Sounak Chakraborty, V. Bala Chaudhary, Monique Gardes, Catherine A. Gehring, Miranda M. Hart, Elizabeth Ann Housworth, Wittaya Kaonongbua, John N. Klironomos, Marc J. Lajeunesse, James Meadow, Brook G. Milligan, Bridget J. Piculell, Anne Pringle, Megan A. Rúa, James Umbanhowar, Wolfgang Viechtbauer, Yen-Wen Wang, Gail W.T. Wilson, Peter C. Zee

Biological Sciences Faculty Publications

Most plants engage in symbioses with mycorrhizal fungi in soils and net consequences for plants vary widely from mutualism to parasitism. However, we lack a synthetic understanding of the evolutionary and ecological forces driving such variation for this or any other nutritional symbiosis. We used meta-analysis across 646 combinations of plants and fungi to show that evolutionary history explains substantially more variation in plant responses to mycorrhizal fungi than the ecological factors included in this study, such as nutrient fertilization and additional microbes. Evolutionary history also has a different influence on outcomes of ectomycorrhizal versus arbuscular mycorrhizal symbioses; the former …

In Re R.R.N.: Redefining "Caretaker" For North Carolina Child Protective Services, Jordan M. Spanner

Campbell Law Review

In 2015, the North Carolina Supreme Court interpreted for the first time the definition of "caretaker" as provided in the State's Juvenile Code. The court narrowed the definition, providing that the statutory language "an adult relative entrusted with the juvenile's care" means an adult relative who has "a significant degree of parental-type responsibility for the child. " The court's interpretation has made caretaker equivalent to in loco parentis, which results in a heightened standard that likely was not intended by the legislature. This Comment discusses the far-reaching effects of the court's decision on North Carolina's child welfare services, law enforcement, …

Caregiver Assessment Using Smart Gaming Technology: A Preliminary Approach, Garrett Goodman, Tanvi Banerjee, William Romine, Cogan Shimizu, Jennifer Hughes

Computer Science and Engineering Faculty Publications

As pre-diagnostic technologies are becoming increasingly accessible, using them to improve the quality of care available to dementia patients and their caregivers is of increasing interest. Specifically, we aim to develop a tool for non- invasively assessing task performance in a simple gaming application. To address this, we have developed Caregiver Assessment using Smart Technology (CAST), a mobile application that personalizes a traditional word scramble game. Its core functionality uses a Fuzzy Inference System (FIS) optimized via a Genetic Algorithm (GA) to provide customized performance measures for each user of the system. With CAST, we match the relative level of …

Closing The Loop: Exploring Ikea’S Transition To The Circular Economy, Alexandra Seidel

Pomona Senior Theses

Inspired by the way nature cycles waste in an ecosystem, the circular economy was developed as an alternative to the linear take-make-dispose model and designed to decouple economic growth from resource use. After developing a framework for what it means to be a business pursuing circularity, this thesis examines six different companies to explore the tension between the strategies and business models in theory and what business are implementing in practice today. This exploration continues with an in-depth analysis of the circular success of IKEA, finding that the gains from the circular economy for a large corporation are found within …

Stewart V. Elk Valley: The Case Of The Cocaine-Using Coal Miner, Faisal Bhabha

All Papers

It has for some time been settled under section 15 of the Charter and within anti-discrimination code definitions that "disability" includes "addictions". Labour boards and human rights tribunals have long accepted that "alcohol and drug addiction are illnesses and are physical and mental disabilities for the purposes of the Human Rights Code. There are no reasons to consider them any less an illness or disability than any other serious affliction."' The shift in expert consensus led to notable changes to the key American diagnostic instrument, the DSM 5, adopted in 2013 with a completely revised approach to addictions. What is …

The Contributions Of Parental, Academic, School, And Peer Factors To Differences By Socioeconomic Status In Adolescents’ Locus Of Control, Dara Shifrer

Sociology Faculty Publications and Presentations

An internal locus of control may be particularly valuable for youth with low socioeconomic status (SES), yet the mechanisms that externalize their control remain unclear. This study uses data on 16,450 US 8th graders surveyed for the National Education Longitudinal Study in 1988 and 1990. Results indicate family income is more closely associated with adolescents’ locus of control than parents’ occupations and educational attainment, and that race does not independently affect adolescents’ locus of control net of these other components of SES. Findings also indicate higher SES adolescents feel more internal locus of control in largest part because their parents …

The Trademark Disclaimer Provision Of The Lanham Act: Is Uspto Flexibility Worth Litigant Ambiguity?, 17 J. Marshall Rev. Intell. Prop. L. 305 (2018), Scott Locke

UIC Review of Intellectual Property Law

Most trademark applicants and the attorneys who counsel them are familiar with the requirement that they disclaim terms within their trademarks because those terms are descriptive or generic. The United States Patent and Trademark Office’s authority to direct applicants to disclaim terms is codified in the Trademark Disclaimer Provision of the Lanham Act, which provides examiners with a great deal of discretion. The same provision has been interpreted as providing applicants with the options of: taking conflicting positions, e.g., that the term is neither descriptive nor generic in the context of their marks, when asserting common law rights; and pursuing …

Effects Of Variable Density Thinning On Spatial Patterns Of Overstory Trees In Mt. Hood National Forest, Emma Huston

Environmental Science and Management Professional Master's Project Reports

Variable density thinning (VDT) is a method of restoration thinning that attempts to increase ecosystem resilience and spatial heterogeneity in forest stands to more closely resemble mosaic-like patterns characteristic of late-successional forests, which consist of clusters of multiple trees, individual trees, and gaps. This study examines the spatial patterning of overstory trees resulting from VDT of conifer forests in Mt. Hood National Forest in the western Cascade Mountains and compares these patterns with reference conditions. Stem maps were created from field surveys of study plots within one mature stand and six thinned stands designated as Late-Successional Reserve (LSR) with varying …

Unmasking The Substance Behind The Process:Why The Duty To Cooperate In International Water Law Is Really A Substantive Principle, Tamar M. Meshel

Denver Journal of International Law & Policy

No abstract provided.

Impact Of Human Disturbance On The Behavior And Physiology Of The Endangered Ringed Sawback Turtle (Graptemys Oculifera), Jessica Mary Heppard

Electronic Theses and Dissertations

Turtles are one of the most threatened taxa worldwide. In addition to direct anthropogenic impacts such as hunting and pollution, unintentional indirect human disturbance affects poikilothermic turtles by disrupting thermoregulatory basking behavior. In this thesis I assess the behavioral and physiologic impacts of high boat traffic, reductions of basking structures, and environmental factors on basking behavior, rates of disturbance, thermoregulation, parasite load, shell condition, and population recruitment in two populations of the endangered ringed sawback (Graptemys oculifera), also known at the ringed map turtle, on the Pearl River outside Jackson, MS. Basking behavior was influenced by availability of basking structures, …

Variables Governing The Initial Stages Of The Synergisms Of Ultrasonic Treatment Of Biochar In Water Saturated With Carbon Dioxide, Adedapo Reuben Adeniyi

Electronic Theses and Dissertations

This work investigates the initial stage of the synergistic processes of acoustic treatment of biochar in water saturated with CO2 (AIChE Journal, 2014;60:1054-1065). Treatments with switchgrass and miscanthus biochars have been conducted to examine the effects of acoustic intensity, biochar/H2O ratio, CO2 concentrations of the solution, and that in the headspace above the solution. The changes in biochars’ heating values, carbon and hydrogen contents, internal surface area, and pore size distribution have significant technological implications and are the focal points of this study. The miscanthus and switchgrass biochars were produced via pyrolysis process at 700 oC and 550 oC, respectively. …

Contents 36(1)

Aliso: A Journal of Systematic and Floristic Botany

No abstract provided.

New Species, New Combinations And New Synonymies Towards A Treatment Of Acanthaceae For The Manual De Plantas De Costa Rica, Lucinda A. Mcdade, Barry E. Hammel, Carrie A. Kiel

Aliso: A Journal of Systematic and Floristic Botany

In preparation for the publication of the Manual de Plantas de Costa Rica, new species, names, combinations, and synonymies are provided in six genera of Acanthaceae: Anisacanthus, Chamaeranthemum, Dicliptera, Justicia, Ruellia and Stenostephanus. The new species are A. grace-woodiae, J. altior, J. lithophila and S. chavesii. A new name at the species level, R. leonardiana, is provided for R. tubiflora var. hirsuta. With Habracanthus, Hansteinia, Kalbreyeriella and Razisea being subsumed within Stenostephanus, the new combinations S. blepharorhachis, S. citrinus, S. leiorhachis (= Razisea spicata …

The Contributions Of United Nations Security Council Resolutions To The Law Of Non-International Armed Conflict: New Evidence Of Customary International Law, Gregory H. Fox, Kristen E. Boon, Isaac Jenkins

American University Law Review

No abstract provided.

De Facto Parent And Non Parent Child Support Orders, Jeffrey A. Parness, Matthew Timko

American University Law Review

No abstract provided.

2017 Patent Law Decisions Of The Federal Circuit, Laura C. Whitworth

American University Law Review

No abstract provided.

Multilabel Learning For The Online Transient Stability Assessment Of Electric Power Systems, Peyman Beyranvand, Veysel Murat İstemi̇han Genç, Zehra Çataltepe

Turkish Journal of Electrical Engineering and Computer Sciences

Dynamic security assessment of a large power system operating over a wide range of conditions requires an intensive computation for evaluating the system's transient stability against a large number of contingencies. In this study, we investigate the application of multilabel learning for improving training and prediction time, along with the prediction accuracy, of neural networks for online transient stability assessment of power systems. We introduce a new multilabel learning method, which uses a contingency clustering step to learn similar contingencies together in the same multilabel multilayer perceptron. Experimental results on two different power systems demonstrate improved accuracy, as well as …

The Effect Of Three Different Mulches On Weed Presence, Soil Characteristics, And Zinnia Growth, Anmar Muttaleb

Murray State Theses and Dissertations

Abstract

Organic and inorganic mulching helps to control weeds. Mulching helps cultivated plants to grow by inhibiting the growth of weeds, retaining soil moisture, and regulating the temperature of soil. The objective of this study was to determine the effects of different organic mulches on weed presence, soil characteristics, and growth of Zinnia elegans. The mulches used in studying Zinnia elegans were wheat straw, non-shredded Miscanthus (M. × giganteus), and shredded Miscanthus (M. × giganteus) mulch. A Randomized Complete Block Design (RCBD) was used in the study, with different quantitative methods were used to …

Abundance Of Methanosaeta Concilii-Like Species In The Sediment Of Ledbetter Creek Embayment Of Kentucky Lake, Juanita Von Dwingelo

Murray State Theses and Dissertations

Reservoirs, including Kentucky Lake, are unique in that they do not follow a natural cycle of rising during the rainy seasons and dropping during the dry summers. The lake is manipulated, mainly for flood control and transportation, so that the water level is increased during the summer months and decreased during the winter months. This manipulation leaves the littoral sediment of the lake submerged in the summer and exposed in the winter. The seasonal water level, along with other factors, like farming practices in the watershed, contributes to the availability of nutrients for organisms inhabiting the sediment of the lake. …

Effects Of Gli-Similar 3 Knockout Mutations On The Expression Of Insulin Transcription And Pancreatic Islet Development In Zebrafish, Dylan James Hammrich

Murray State Theses and Dissertations

Blood glucose homeostasis is a critical component in the physiological health of vertebrates. Regulation of blood glucose levels is the responsibility of the endocrine pancreas, which excretes hormones to the bloodstream in response to changes in glucose concentrations. The hormones excreted from the pancreas include insulin, which is secreted form the β cells of the pancreas and signals uptake of excess glucose by the peripheral tissues, and glucagon, which is secreted from the α cells and signals release of glucose to the bloodstream through gluconeogenesis in the liver. The Krüppel-like zinc finger protein Gli-Similar 3 (Glis3) is a transcription factor …

Trophic Interactions And Niche Partitioning Within A Post-White-Nose Syndrome Temperate Bat Community, Macy Kailing

Murray State Theses and Dissertations

The decline of cave-dwelling bats since the introduction of white-nose syndrome (WNS) to North America changed the way communities interact. Disease-mediated competition at the community level can influence the ability of imperiled species to recover because of competitive exclusion. In western Kentucky, tri-colored bats, Perimyotis subflavus, which are susceptible to WNS severely declined following WNS occurrence. During that same period, evening bats, Nycticeius humeralis, which are not susceptible to WNS increased markedly. To investigate the influence of WNS on community structure, the diets of sympatric tri-colored and evening bats were assessed. Guano was collected from evening (n=37) and …

Predator Presence And Size Variation Alters Community Structure Through Multiple Trophic Cascades, Robin Baker, Howard Whiteman Ph.D.

Murray State Theses and Dissertations

Predation plays a crucial role in shaping community structure and can initiate trophic cascades that can alter abundances across adjacent trophic levels. Recent research has suggested that variation among individual predators may have stronger effects on ecological dynamics than previously appreciated. Intraspecific variation within predators could lead to differential levels of top-down control with implications for trophic cascade strength. In this experiment, we manipulated the body size variation of predatory mole salamanders (Ambystoma talpoideum) within experimental mesocosms and monitored a suite of abiotic and biotic response variables. We predicted that predator populations with increased body size variation would …