Digital Commons Network^™

Interpretations Of The Clean Water Act Are As Muddy And Polluted As The Water The Act Seeks To Protect, Lauren Keeler

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Evaluating Blended And Flipped Instruction In Numerical Methods At Multiple Engineering Schools, Renee M. Clark, Autar Kaw, Yingyan Lou, Andrew Scott, Mary Besterfield-Sacre

Mechanical Engineering Faculty Publications

With the literature calling for comparisons among technology-enhanced or active-learning pedagogies, a blended versus flipped instructional comparison was made for numerical methods coursework using three engineering schools with diverse student demographics. This study contributes to needed comparisons of enhanced instructional approaches in STEM and presents a rigorous and adaptable methodology for doing so. Our flipped classroom consisted mostly of in-class active learning, with micro-lectures as needed, and technology used both in and out of class, including for expected pre-class review of new content. Our blended classroom consisted mostly of lecture with some in-class active learning, and technology utilized both in …

The Delaware Half-Hardies, Ian Stewart, Jim White, Joe Sebastiani

Delaware Ornithologist

No abstract provided.

Nitazoxanide Inhibits Paramyxovirus Replication By Targeting The Fusion Protein Folding: Role Of Glycoprotein-Specific Thiol Oxidoreductase Erp57, Sara Piacentini, Simone La Frazia, Anna Riccio, Jens Z. Pederson, Alessandra Topai, Orazio Nicolotti, Jean-Francois Rossignol, M. G. Santoro

Epidemiology and Biostatistics Faculty Publications

Paramyxoviridae, a large family of enveloped viruses harboring a nonsegmented negative-sense RNA genome, include important human pathogens as measles, mumps, respiratory syncytial virus (RSV), parainfluenza viruses, and henipaviruses, which cause some of the deadliest emerging zoonoses. There is no effective antiviral chemotherapy for most of these pathogens. Paramyxoviruses evolved a sophisticated membrane-fusion machine consisting of receptor-binding proteins and the fusion F-protein, critical for virus infectivity. Herein we identify the antiprotozoal/antimicrobial nitazoxanide as a potential anti-paramyxovirus drug targeting the F-protein. We show that nitazoxanide and its circulating-metabolite tizoxanide act at post-entry level by provoking Sendai virus and RSV F-protein aggregate …

Body Mass Index At Pediatric Leukemia Diagnosis And The Risks Of Relapse And Mortality: Findings From A Single Institution And Meta-Analysis, Ashleigh M. Saenz, Stacie Stapleton, Raquel G. Hernandez, Greg A. Hale, Neil A. Goldenberg, Skai W. Schwartz, Ernest K. Amankwah

Epidemiology and Biostatistics Faculty Publications

High body mass index (BMI) is associated with relapse of certain adult cancers, but limited knowledge exists on its association with pediatric leukemia relapse. We evaluated the association between overweight/obesity (BMI ≥ 85th percentile) at pediatric leukemia diagnosis and relapse or mortality. A meta-analysis combining our findings with those of previous studies was also performed. The study included 181 pediatric leukemia patients. Sporadic missing data were multiply imputed, and hazard ratios (HR) and 95% confidence intervals (95% CI) were calculated using Cox proportional hazard. Age- and sex-adjusted analysis for patients ≥10 years showed a trend towards increased risk of relapse …

Effect Of A Novel Photoelectrochemical Oxidation Air Purifier On Nasal And Ocular Allergy Symptoms, Nikhil G. Rao, Ambuj Kumar, Jenny S. Wong, Ravi Shridhar, Dharendra Y. Goswami

Chemical, Biological and Materials Engineering Faculty Publications

Background: Photoelectrochemical oxidation (PECO) is a new air purification technology developed to reduce circulating indoor allergens. PECO removes particles as small as 0.1 nm with the destruction of organic matter otherwise not trapped by a traditional filter and removes volatile organic compounds.

Objective: We hypothesized that with daily use, the device would reduce user nasal and ocular allergy total symptom scores (TSS) within 4 weeks.

Methods: The study was performed among 46 individuals with self-reported allergies using a portable PECO air purifier. Self-reported TSS were calculated at baseline and weekly for 4 weeks following initiation of continuous use of the …

Grand Valley Magazine, Vol. 17, No. 3 Winter 2018, Grand Valley State University

Grand Valley Magazine

Grand Valley Magazine is a quarterly publication about Grand Valley State University produced by University Communications since 2001.

Throwing The Baby Out With The Patriarchy, Scott Titshaw

Articles

Throughout the history of Europe and its former new world colonies, families have been a central unit for defining legal rights and duties, including those related to citizenship and immigration. Less than a century ago, a woman and her children automatically gained or lost citizenship in the U.S. and many other countries upon her marriage to a citizen or noncitizen. The family was treated as one unit reflecting the legal identity of the father-husband as “head of family.”

Fortunately, the United States and other governments have increasingly recognized women – and, to a lesser extent, children – as independent persons …

A Logical Step Forward: Extending Voluntary Acknowledgments Of Parentage To Female Same-Sex Couples, Jessica Feinberg

Articles

Under current law, stark differences exist between different- and same-sex couples who welcome children into the world with regard to the ease through which the member of the couple who did not give birth to the child is able to obtain legal parent status. While a number of simple, efficient procedures exist for establishing legal parentage for different-sex partners of women who give birth, same-sex partners of women who give birth often have to go through significantly more complex, time-consuming, and expensive procedures in order to establish legal parentage. The inequitable treatment of same-sex couples in establishing legal parentage has …

Fintech: Antidote To Rent-Seeking?, Jeremy Kidd

Articles

Fintech is a reality of our modern society, and will likely become even more so in the future. Peer-to-peer lending, cybercurrencies, smart contracts, algorithmic lending, and more, have required adaptation by consumers and producers of financial services. Our modes of doing business will continue to be challenged and changed by these and other Fintech innovations, almost certainly expanding beyond merely “promot[ing] financial inclusion, expand[ing] access to capital for individuals and small businesses, and more broadly reshap[ing] how society interacts with financial services.” By reducing transaction costs, advancing technology opens the doors to innovations the likes of which we might not …

2018 Spring - Veterans Upward Bound Newsletter, Veterans Upward Bound, East Tennessee State University

Veterans Upward Bound Newsletters

No abstract provided.

Indigenous-Led Resistance To Environmental Destruction: Methods Of Anishinaabe Land Defense Against Enbridge's Line 3, Charlotte Degener Hughes

Pitzer Senior Theses

Enbridge has proposed the Line 3 “Replacement” Project, a new pipeline project taking a new route strait through Anishinaabe treaty territory in what is known as northern Minnesota. In the middle of the regulation process, the future remains unclear of how the State of Minnesota will move forward with the permitting process, but Anishinaabe communities, a range of non-profit organizations, and local landowners remain firmly against the line. Rooted in varied frameworks of Native sovereignty, the land, and Indigenous feminism, Anishinaabe communities lead the resistance against a product of ongoing settler colonialism, racial capitalism, and environmental racism. This thesis contextualizes …

Muslim Arab American Parents Perceptions, Beliefs, Knowledge, And Actions In Regard To Special Education, Soufiane Benalla

All-Inclusive List of Electronic Theses and Dissertations

The current study explored a group of Muslim Arab American parents perceptions, beliefs, knowledge, and actions regarding special Education. Using a phenomenological and interpretivist theoretical framework, this qualitative study investigated the Muslim Arab American parents socially and culturally constructed realities through accounts of their lived experiences (Fay, 1996). The participants were from the Indianapolis area. This study included a total of 13 participants; six were Muslim Arab American parents with children in special Education and seven parents without children in special Education. A researcher-designed interview protocol systematically related to the research questions and the literature review was used to collect …

Attitudes Towards Dependent Personality Disorder: The Role Of Sex And Sexual Orientation, Brandon Sentell

All-Inclusive List of Electronic Theses and Dissertations

Relatively little research has focused on Dependent Personality Disorder (DPD) and even less research has examined sex differences, despite evidence of sex differences in prevalence of DPD and evidence that DPD is perceived as a feminine PD. Men who demonstrate DPD symptoms might be perceived as violating the male sex role and therefore risk being seen as more dysfunctional or labeled homosexual. However, there is a dearth of research regarding attitudes towards men with DPD, and no known research investigating attitudes towards gay and lesbian individuals with DPD. Undergraduates ( n = 318) read one of four versions of a …

Considerations In The Classification Of Orthorexia Nervosa, Bethany Garcia

All-Inclusive List of Electronic Theses and Dissertations

Orthorexia nervosa has been suggested as a new psychological phenomenon in which an individual restricts their diet to consume only biologically pure and healthy foods. Some have suggested that orthorexia nervosa should be considered a new eating disorder. However, it is unclear at this time if orthorexia nervosa is a new psychological disorder, a variant of an existing psychological disorder (such as anorexia nervosa or obsessive-compulsive disorder), or a sub-threshold disordered eating behavior. The present study examined and compared measures of orthorexia nervosa behavior, explored its relationship to other psychological conditions, and assessed how demographic features are related to the …

An American Myth In The (Re)Making: The Timeless Fantasy Appeal Of 'The King And I', Lina Purtscher

Scripps Senior Theses

It is now well-known that The King and I has little claim to truth. Recent research has exposed the inaccuracy of the “biographical” works on which the musical is based: Anna Leonowens invented many things about her personal background and experiences. Much of her life, then, is a contrived fantasy. Yet her life of fantasy has been resurrected in countless adaptations, including the 1951 Rodgers and Hammerstein musical and its 2015 revival production, that ceaselessly draw audiences. The fascination of American audiences with Anna’s tale lies their belief in the timeless American ideals that her fantasy employs: those of freedom …

Contrasting Impacts Of Competition On Ecological And Social Trait Evolution In Songbirds, Jonathan P. Drury, Joseph A. Tobias, Kevin J. Burns, Nicholas A. Mason, Allison J. Shultz, Hélène Morlon

Faculty Publications

© 2018 Drury et al. Competition between closely related species has long been viewed as a powerful selective force that drives trait diversification, thereby generating phenotypic diversity over macroevolutionary timescales. However, although the impact of interspecific competition has been documented in a handful of iconic insular radiations, most previous studies have focused on traits involved in resource use, and few have examined the role of competition across large, continental radiations. Thus, the extent to which broad-scale patterns of phenotypic diversity are shaped by competition remain largely unclear, particularly for social traits. Here, we estimate the effect of competition between interacting …

Challenges Of Elephant Conservation: Insights From Oral Histories Of Colonialism And Landscape In Tsavo, Kenya, Peter Ngugi Kamau, Andrew Sluyter

Faculty Publications

No abstract provided.

The Case For Streamlining Emergency Declaration Authorities And Adapting Legal Requirements To Ever-Changing Public Health Threats, Gregory Sunshine

Emory Law Journal

This Article makes the case for streamlining emergency declaration authority and creating an adaptable legal system. Part I describes the utility of emergency declarations, but gives examples of how that utility can be diminished when states divide specific emergency powers across various types of declarations. Part II explores gubernatorial emergency powers to suspend or waive laws as an adaptable solution for removing legal barriers to an efficient and effective emergency response. These arguments demonstrate that a streamlined and adaptable state legal system for emergency response is one that (1) provides a governor with the authority to issue one type of …

A New Ultrasonic Transducer Sample Cell For In Situ Small-Angle Scattering Experiments, Sudipta Gupta, Markus Bleuel, Gerald J. Schneider

Faculty Publications

© 2018 Author(s). Ultrasound irradiation is a commonly used technique for nondestructive diagnostics or targeted destruction. We report on a new versatile sonication device that fits in a variety of standard sample environments for neutron and X-ray scattering instruments. A piezoelectric transducer permits measuring of the time-dependent response of the sample in situ during or after sonication. We use small-angle neutron scattering (SANS) to demonstrate the effect of a time-dependent perturbation on the structure factor of micelles formed from sodium dodecyl sulfate surfactant molecules. We observe a substantial change in the micellar structure during and after exposure to ultrasonic irradiation. …

Maternal Bodies: Redefining Motherhood In Early America, Jennifer L. Gross

Civil War Book Review

In Maternal Bodies, winner of the prestigious Allan Nevins Prize from the Society of American Historians, Nora Doyle explores the tension between women’s lived experiences of motherhood, both physical and emotional, and the cultural representations of motherhood that began to emerge in the second half of the eighteenth century. In terms of women’s experiences of motherhood, Doyle notes significant continuity. For example, despite the fact that the average number of children American women bore and reared did decrease during the period, “childbearing and childrearing continued to define most women’s lives” (2). Another example of continuity during the era was that …

Novel Spiroplasma Spp. Cultured From Brains And Lymph Nodes From Ruminants Affected With Transmissible Spongiform Encephalopathy, Frank O. Bastian, James Lynch, Sue Hagius, Xiaochu Wu, Greg Mccormick, Donald G. Luther, Philip H. Elzer

Faculty Publications

© 2017 American Association of Neuropathologists, Inc. Spiroplasma spp., tiny filterable wall-less bacteria, are consistently associated with the transmissible spongiform encephalopathies (TSE). Spiral forms have been transiently isolated from TSE-affected brain tissues in SP4 growth media designed for isolation of Spiroplasma spp., but the isolate could not be propagated in SP4 media. A bacterium must grow in vitro in cell-free cultures to allow full characterization of a suspect pathogen. Here, a novel Spiroplasma sp. was isolated from scrapie- and chronic wasting disease (CWD)-affected brains and lymph nodes. Filtrates of tissue homogenates inoculated into Brucella media incubated for 14 days at …

Nanotechnology Considerations For Poultry And Livestock Production Systems - A Review, Mohamed I. El Sabry, Kenneth W. Mcmillin, Cristina M. Sabliov

Faculty Publications

© 2018 by Mohamed I. El Sabry. The global animal productivity should proportionally increase to meet the food needs of a growing population. This article presents an overview of the current and promising nano-applications in poultry and livestock production systems that could offer opportunities for improved efficiencies and productivity. Some basic information on nanotechnology and the economics of nanotechnology is provided. Poultry and animal production systems, current situation and available tools and techniques are presented in parallel with animal health care, animal nutrition, animal shetter and food processing nano-applications and their advantages. These applications are directly or indirectly related to …

Ex Vivo Gut Culture For Studying Differentiation And Migration Of Small Intestinal Epithelial Cells, Xiaofei Sun, Xing Fu, Min Du, Mei Jun Zhu

Faculty Publications

© 2018 The Authors. Epithelial cultures are commonly used for studying gut health. However, due to the absence of mesenchymal cells and gut structure, epithelial culture systems including recently developed three-dimensional organoid culture cannot accurately represent in vivo gut development, which requires intense cross-regulation of the epithelial layer with the underlying mesenchymal tissue. In addition, organoid culture is costly. To overcome this, a new culture system was developed using mouse embryonic small intestine. Cultured intestine showed spontaneous peristalsis, indicating the maintenance of the normal gut physiological structure. During 10 days of ex vivo culture, epithelial cells moved along the gut …

Gata4-Dependent Differentiation Of C-Kit+-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration In The Heart, Bryan D. Maliken, Onur Kanisicak, Jason Karch, Hadi Khalil, Xing Fu, Justin G. Boyer, Vikram Prasad, Yi Zheng, Jeffery D. Molkentin

Faculty Publications

© 2018 The Authors. BACKGROUND: Although c-Kit+ adult progenitor cells were initially reported to produce new cardiomyocytes in the heart, recent genetic evidence suggests that such events are exceedingly rare. However, to determine if these rare events represent true de novo cardiomyocyte formation, we deleted the necessary cardiogenic transcription factors Gata4 and Gata6 from c-Kit-expressing cardiac progenitor cells. METHODS: Kit allele-dependent lineage tracing and fusion analysis were performed in mice following simultaneous Gata4 and Gata6 cell type-specifc deletion to examine rates of putative de novo cardiomyocyte formation from c-Kit+ cells. Bone marrow transplantation experiments were used to defne the contribution …

Phylogenomics Of Pike Cichlids (Cichlidae: Crenicichla): The Rapid Ecological Speciation Of An Incipient Species Flock, E. D. Burress, F. Alda, A. Duarte, M. Loureiro, J. W. Armbruster, P. Chakrabarty

Faculty Publications

© 2017 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2017 European Society For Evolutionary Biology The rapid rise of phenotypic and ecological diversity in independent lake-dwelling groups of cichlids is emblematic of the East African Great Lakes. In this study, we show that similar ecologically based diversification has occurred in pike cichlids (Crenicichla) throughout the Uruguay River drainage of South America. We collected genomic data from nearly 500 ultraconserved element (UCEs) loci and >260 000 base pairs across 33 species, to obtain a phylogenetic hypothesis for the major species groups and to evaluate the relationships and genetic …

Variation Across Mitochondrial Gene Trees Provides Evidence For Systematic Error: How Much Gene Tree Variation Is Biological?, Emilie J. Richards, Jeremy M. Brown, Anthony J. Barley, Rebecca A. Chong, Robert C. Thomson

Faculty Publications

© The Author(s) 2018. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. The use of large genomic data sets in phylogenetics has highlighted extensive topological variation across genes. Much of this discordance is assumed to result from biological processes. However, variation among gene trees can also be a consequence of systematic error driven by poor model fit, and the relative importance of biological vs. methodological factors in explaining gene tree variation is a major unresolved question. Using mitochondrial genomes to control for biological causes of gene tree variation, we estimate the extent …

Isolation By Distance, Not Incipient Ecological Speciation, Explains Genetic Differentiation In An Andean Songbird (Aves: Furnariidae: Cranioleuca Antisiensis, Line-Cheeked Spinetail) Despite Near Threefold Body Size Change Across An Environmental Gradient, Glenn F. Seeholzer, Robb T. Brumfield

Faculty Publications

© 2017 John Wiley & Sons Ltd During the process of ecological speciation, reproductive isolation results from divergent natural selection and leads to a positive correlation between genetic divergence and adaptive phenotypic divergence, that is, isolation by adaptation (IBA). In natural populations, phenotypic differentiation is often autocorrelated with geographic distance, making IBA difficult to distinguish from the neutral expectation of isolation by distance (IBD). We examined these two alternatives in a dramatic case of clinal phenotypic variation in an Andean songbird, the Line-cheeked Spinetail (Cranioleuca antisiensis). At its geographic extremes, this species shows a near threefold difference in body mass …

Parent And Family Guide, 2018-2019, Illinois State University, Dean Of Students Office, Parent And Family Services

Parent and Family Guide

Campus guide prepared by the Illinois State University Dean of Students Office's Parent and Family Services Department

Martin Luther King's Beloved Community And European Trumpism, Henry J. Richardson Iii

Valparaiso University Law Review

No abstract provided.