Digital Commons Network^™

Athletics

DePaul Magazine

A Year to Celebrate: Annual banquet honors athletic milestones; Athletics Banquet Award Winners; Most Outstanding Performer; 50th Special Olympics; Athletics Briefs

H3k9 Methyltransferases And Demethylases Control Lung Tumor-Propagating Cells And Lung Cancer Progression, S. P. Rowbotham, F Li, A. F. M. Dost, S. M. Louie, B. P. Marsh, P. Pessina, C. R. Anbarasu, Christine Fillmore Brainson, S. J. Tuminello, A. Lieberman, S. Ryeom, T. M. Schlaeger, B. J. Aronow, H. Watanabe, K. K. Wong, C. F. Kim

Toxicology and Cancer Biology Faculty Publications

Epigenetic regulators are attractive anticancer targets, but the promise of therapeutic strategies inhibiting some of these factors has not been proven in vivo or taken into account tumor cell heterogeneity. Here we show that the histone methyltransferase G9a, reported to be a therapeutic target in many cancers, is a suppressor of aggressive lung tumor-propagating cells (TPCs). Inhibition of G9a drives lung adenocarcinoma cells towards the TPC phenotype by de-repressing genes which regulate the extracellular matrix. Depletion of G9a during tumorigenesis enriches tumors in TPCs and accelerates disease progression metastasis. Depleting histone demethylases represses G9a-regulated genes and TPC phenotypes. Demethylase inhibition …

Sequence Pattern Mining With Variables, James S. Okolica, Gilbert L. Peterson, Robert F. Mills, Michael R. Grimaila

Faculty Publications

Sequence pattern mining (SPM) seeks to find multiple items that commonly occur together in a specific order. One common assumption is that all of the relevant differences between items are captured through creating distinct items, e.g., if color matters then the same item in two different colors would have two items created, one for each color. In some domains, that is unrealistic. This paper makes two contributions. The first extends SPM algorithms to allow item differentiation through attribute variables for domains with large numbers of items, e.g, by having one item with a variable with a color attribute rather than …

The Guardian, Week Of November 19, 2018, Wright State University Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of November 19, 2018. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Statistical Multi-Way Relationships Of Human Brain Activity, Chen Feng

Theses

The human brain activity is a popular and important topic in the medical science field and academic studies. In recent years, scientists have been applying various statistical methods to analyze human brain activity. Correlation between brain regions is the most common and fundamental method used to perform this task. However, correlation describes only a two-way relationship. This work explores a new approach by analyzing multi-way relationships. Due to computational complexities, we concentrate on three-way relationships. In particular, we compare conventional two-way correlations and three-way regression models. Data transformed and processed from 3,280 MRI scans of the human brain are used …

Mapping The Citation Flow Of New York Times Newspaper Indexed In Web Of Science, Angom Jeevan Singh

Library Philosophy and Practice (e-journal)

The objective of the paper is to find out the flow of the New York Times newspaper information in scholarly publication during 2001-2010. New York Times is considered for the present study since it is the most highly cited English newspaper indexed in Web of Science. During the study period there were 13600 records with 14764 citations in different scholarly publications. The citation of the New York Times in scholarly publications increased gradually from 2005 onwards. The study also found that there is gradual increase in citing Byline newspaper information from 2005 onwards in scholarly publications, whereas, there is gradual …

Defining Landscape-Scale Collaboration As Used To Restore Forests And Reduce Catastrophic Wildfires, Marcelle Elise Dupraw 2512721

The Qualitative Report

In this article, I explore the distinctive characteristics of landscape-scale collaboration in the context of forest resource management in the United States. The United States (US) is experiencing a significant increase in acres burned by wildfire in the wildland-urban interface zone, exacting a heavy toll on human life, health, property, and livelihoods. The US Forest Service’s Collaborative Forest Landscape Restoration (CFLR) Program demonstrates an effective approach to reducing risk of catastrophic wildfire through collaborative forest restoration work at the landscape scale. This is the first in a series of articles building toward a grounded theory to guide development of the …

Spending Too Little In Hard Times, Alessandro Del Ponte, Peter Descioli

Political Science Faculty Articles and Research

People’s decisions to consume and save resources are critical to their wellbeing. Previous experiments find that people typically spend too much because of how they discount the future. We propose that people’s motive to preserve their savings can instead cause them to spend too little in hard times. We design an economic game in which participants can store resources for the future to survive in a harsh environment. A player’s income is uncertain and consumption yields diminishing returns within each day, creating tradeoffs between spending and saving. We compare participants’ decisions to a heuristic that performed best in simulations. We …

Military-Related Exposures, Social Determinants Of Health, And Dysbiosis: The United States-Veteran Microbiome Project (Us-Vmp), Lisa A. Brenner, Andrew J. Hoisington, Kelly A. Stearns-Yoder, Christopher E. Stamper, Jared A. Heinze, Teodor T. Postolache, Daniel A. Hadidi, Claire A. Hoffmire, Maggie A. Stanislawski

Faculty Publications

Significant effort has been put forth to increase understanding regarding the role of the human microbiome in health- and disease-related processes. In turn, the United States (US) Veteran Microbiome Project (US-VMP) was conceptualized as a means by which to serially collect microbiome and health-related data from those seeking care within the Veterans Health Administration (VHA). In this manuscript, exposures related to military experiences, as well as conditions and health-related factors among patients seen in VHA clinical settings are discussed in relation to common psychological and physical outcomes. Upon enrollment in the study, Veterans complete psychometrically sound (i.e., reliable and valid) …

A Comparison Of Machine Learning Techniques For Taxonomic Classification Of Teeth From The Family Bovidae, Gregory J. Matthews, Juliet K. Brophy, Maxwell Luetkemeier, Hongie Gu, George K. Thiruvathukal

Faculty Publications

This study explores the performance of machine learning algorithms on the classification of fossil teeth in the Family Bovidae. Isolated bovid teeth are typically the most common fossils found in southern Africa and they often constitute the basis for paleoenvironmental reconstructions. Taxonomic identification of fossil bovid teeth, however, is often imprecise and subjective. Using modern teeth with known taxons, machine learning algorithms can be trained to classify fossils. Previous work by Brophy et al. [Quantitative morphological analysis of bovid teeth and implications for paleoenvironmental reconstruction of plovers lake, Gauteng Province, South Africa, J. Archaeol. Sci. 41 (2014), pp. 376–388] uses …

An Intensive, Large-Scale Batch Culture System To Produce The Calanoid Copepod, Acartia Tonsa: Appendix A, Brie L. Sarkisian, Jason T. Lemus, Angelos Apeitos, Reginald B. Blaylock, Eric Saillant

Research Data

No abstract provided.

Classifying Aneugens Using Functional Data Analysis Techniques, Daniel Gremmell

Theses

In the field of genetic toxicology the term aneugen is used to indicate chemical or physical agents that cause chromosomes to malsegregate during division, thereby resulting in altered DNA content in daughter cells. This form of chromosome damage can be detected in certain mammalian cell-based assays, however the molecular mechanism(s) responsible for aneugenic effects are not apparent from these conventional tests. However, the responsible molecular initiating event (MIE) is of interest to pharmaceutical, chemical, and agro-chemical industries, because this knowledge can assist their efforts to design out such liabilities and/or avoid similar chemical structures altogether. This study evaluated the ability …

Warm-Season Grass Monocultures And Mixtures For Sustainable Bioenergy Feedstock Production In The Midwest, Usa, Moon-Sub Lee, Robert B. Mitchell, Emily Heaton, Colleen Zumpf, Dokyoung Lee

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Biomass yield and adaptability to a broad range of environments are important characteristics of dedicated energy crops for sustainable bioenergy feedstock production. In addition to yield potential, the role of species diversity on ecosystem services is also growing in importance as we seek to develop sustainable feedstock production systems. The objective of this study was to compare the biomass yield potential of the commercially available germplasm of native warm-season grasses in monocultures and in blends (mixture of different cultivars of the same species) or mixtures of different species across an environmental gradient (temperature and precipitation) in the Midwest, USA. Warm-season …

Grandma's Shaking Ghost, Amber Utterback

USU Student Folklore Fieldwork

My grandparents moved a mobile home onto our property when my dad got sick. They now permanently live on the bottom of our hill. My cousins, my brother and I would spend the night almost every weekend in the summer. My grandparents have a coveted guestroom that we would all fight over because one of my cousins snored and we didn’t want to share the living room with her. One night, I was the lucky one so I got to sleep in the room by myself. It was at the end of the house and the twin bed was set …

Leveille, Lee, Student Interviewer

Querying the Past: LGBTQ Maine Oral History Project Collection

Lee Leveille is a 30-year-old Californian transplant that grew up in Sumner and Greene, ME. S/he works as an intentional peer support specialist in central Maine and is currently finishing up his/her bachelor’s in Psychology and Community Studies at the University of Maine at Machias. S/he is an active member of his/her local synagogue after beginning the conversion process to Judaism in 2016.

Lee considers him/herself to be a transgender butch, or someone who lives simultaneously as both a butch woman and transman. His/her pronouns are thus conditional in order to provide him/her with the flexibility to adapt to different …

Meow Meow, Amber Utterback

USU Student Folklore Fieldwork

A couple of years ago, I was getting home late from a church activity. We live on a farm in the middle of nowhere, our barn is across the driveway from our house, far enough away that the light from the front porch can’t reach the entrance to the barn. We never shut the large barn door--this door is big enough for tractors and stuff to pull through and at night it is pitch black in there. We always enter in through the garage so the garage door is always open too, but my parents never remember to turn the …

Phytonutrient Intake And Body Composition Color Correlations, Ryan Orgeron

Master's Theses

This study evaluated the role of phytonutrient intake on body composition. Both the quantity and types of phytonutrients in diets were analyzed. Fifty (50) subjects (15 males; 35 females) from Thibodaux, Louisiana, were randomly selected to participate. All participants completed three 24-hour food recalls to gather intake data (food and calorie intake). The phytonutrient index (PI) was an established formula used to calculate the percentage (%) of the diet comprised of phytonutrient rich foods. Three different body assessment tools were used to determine body adiposity (body mass index [BMI], waist circumference, and fat percentage).

Participants who met healthy standards for …

Electrical Characterization Of Graphene And Nanodiamond Nanostructures, A Z M Nowzesh Hasan

Doctoral Dissertations

The electrical characterization on two-dimensional carbon-based graphene and nanodiamond materials was performed to improve charge transport properties for the label-free electrical biosensors. The charge transport in solution-gated graphene devices is affected by the impurities and disorders of the underlying dielectric interface and its interaction with the electrolytes. Advancement in field-effect ion sensing by introducing a dielectric isomorph, hexagonal boron nitride between graphene and silicon dioxide of a solution-gated graphene field-effect transistor was investigated. Increased transconductance due to increased charge carrier mobility is accompanied with larger ionic sensitivity. These findings define a standard to construct future graphene devices for biosensing and …

Multidimensional Feature Engineering For Post-Translational Modification Prediction Problems, Norman Mapes Jr.

Doctoral Dissertations

Protein sequence data has been produced at an astounding speed. This creates an opportunity to characterize these proteins for the treatment of illness. A crucial characterization of proteins is their post translational modifications (PTM). There are 20 amino acids coded by DNA after coding (translation) nearly every protein is modified at an amino acid level. We focus on three specific PTMs. First is the bonding formed between two cysteine amino acids, thus introducing a loop to the straight chain of a protein. Second, we predict which cysteines can generally be modified (oxidized). Finally, we predict which lysine amino acids are …

Engineered Coating Of Natural Fibers And Oil-Water Interfaces With Self-Assembly Of Clay Nanotubes, Abhishek Panchal

Doctoral Dissertations

Taking into consideration two different types of surfaces, this dissertation proposes techniques to coat the surface of natural fibers and oil-water interfaces by spontaneous self-assembly of halloysite clay nanotubes. The material of choice, halloysite clay, is a widely available natural resource and can be used after minimal processing. In regards to chemical composition, halloysite clay resembles aluminosilicate mineral kaolin; physically, a defect in the crystal structure ordering causes the sheets of kaolinite to roll into halloysite nanotubes. The dimensions of halloysite nanotubes are dependent on the source, but generally vary from 200 nm to 3 µm in length, 100-150 nm …

A Time Series Of Water Column Distributions And Sinking Particle Flux Of Pseudo-Nitzschia And Domoic Acid In The Santa Barbara Basin, California, Blaire P. Umhau, Claudia R. Benitez-Nelson, Clarissa R. Anderson, Kelly Mccabe, Christopher Burrell

Faculty Publications

Water column bulk Pseudo-nitzschia abundance and the dissolved and particulate domoic acid (DA) concentrations were measured in the Santa Barbara Basin (SBB), California from 2009–2013 and compared to bulk Pseudo-nitzschia cell abundance and DA concentrations and fluxes in sediment traps moored at 147 m and 509 m. Pseudo-nitzschia abundance throughout the study period was spatially and temporally heterogeneous (L⁻¹ to 3.8 × 10⁶ cells L⁻¹, avg. 2 × 10⁵ ± 5 × 10⁵ cells L⁻¹) and did not correspond with upwelling conditions or the total DA (tDA) concentration, which was also spatially …

Photoremediation Of Organic Compounds With Fullerene (C60) Modified Tio2 Nanoparticles, Raymond Patey

Theses and Dissertations

Historically the populations of many developing countries have been subjected to potable water shortages through drought and those of developed nations from pollution because of industrialization. Recently parts of our own country were in dire straits when it comes to the availability of clean drinking water due to severe drought. Existing inert processes involving activated carbon and titanium dioxide (TiO2) coated particles and membranes have shown to be effective at water purification. However, processes such as these typically require expensive infrastructure and filtration systems and consequently are not expected to be found in developing countries, where clean water is severely …

What Are We Teaching Abroad? Faculty Goals For Short-Term Study Abroad Courses, Elizabeth Niehaus, Ashley Wegener

Department of Educational Administration: Faculty Publications

Based on survey data from over 400 faculty members who taught short-term study abroad courses, the purpose of this study was to identify the types of goals that faculty members have in teaching short-term study abroad courses and the relationship between faculty background characteristics (i.e., race, gender, discipline, and prior experience) and their teaching goals. By further understanding the goals that these faculty members have for their study abroad programs, we are better able to assess how these programs may or may not be meeting overall internationalization goals and then to use this information to assist faculty members and higher …

Mississippi River Basin Initiative At Bayou Meto And Bayou Bartholomew Watersheds, Tomekia White

Theses and Dissertations

The quality and quantity of water in the Mississippi River Basin is of great national importance. As the production of agricultural crops increases in this area, it is very important that monitoring and data analysis plans be implemented aggressively. The National Resources and Conservation Service (NRCS) has developed the Mississippi River Basin Initiative which includes Arkansas as one of 13 states that is participating in this initiative. To date, Arkansas is known as the number one producer of the nation’s rice, bait fish, sport fish, and feeder fish, number two in broiler production, number three in catfish and number six …

Setting Sights On Campus Safety: The Possibility Of Firearms On Campus And Campus Violence Prevention, Casey Graham Brown

School Leadership Review

PK-12 school leaders spend a sizeable amount of time discussing, facilitating, and contemplating school safety and security. University administrators do as well, although their discussion and contemplation in some states has been scattered with controversies of allowing weapons on university campuses. School administrators seek to keep weapons out; many university administrators do also, although the legislatures of multiple states have allowed their presence on university campuses.

Characterization Of A Basement Membrane Associated Protein Encoding Gene In Drosophila Melanogaster, Aref Ranjbar, Ajay Srivastava

Posters-at-the-Capitol

Title: Characterization of a Basement Membrane Associated Protein Encoding Gene in Drosophila melanogaster

Authors: Aref Ranjbar, Mayank Kapadia, Ajay Srivastava, PhD(faculty member, mentor)

Basement Membranes (BM) are important for normal development and tumor progression. In order to get a better understanding of BM dynamics we identified genes that encoded BM interacting proteins. One such gene is predicted to be involved in vesicle-mediated transport in Drosophila melanogaster. Here we characterize this gene by utilizing molecular biology techniques like immunohistochemistry, RNA in situ hybridization, and Western blot analysis utilizing antibodies generated in the laboratory. Western blot analysis identified this protein to be …

Novel Inactivation Of The Causative Fungus Of White Nose Syndrome With Methoxsalen And Ultraviolet A Light, Colin J. Hartman, Joseph Mester Phd, Alan Cohen Md

Posters-at-the-Capitol

White Nose Syndrome (WNS) is a newly recognized disease responsible for the rapid mass destruction of the North American bat populations. This study addressed the novel inactivation of fungal spores from Pseudogymnoascus destructans, the causative agent of WNS, using ultraviolet A (UVA) light at 365nm and methoxsalen, a photosensitizer from a family of compounds known as furanocoumarins. Penicillium crustosum, an environmental fungus, was studied as a comparator.

Spore suspensions were soaked in specific concentrations of methoxsalen and subsequently exposed to UVA light. The plates were examined for both spore inactivation and resultant inhibition of colony growth. The results demonstrated …

Discovery Of Unreported Sponge Taxa, With Potential As Species New To Science, From The Chicago Area, Jennifer E. Slate

Faculty Research and Creative Activities Symposium

No abstract provided.

Spiral Waves Modeling, Paulo H. Acioli

Faculty Research and Creative Activities Symposium

No abstract provided.

25 Years Of Battling Academic Hegemony, Gender Stereotypes And Political Power: Deconstructing The Mantis Visual System In The Service Of Helping Children, Frederick R. Prete

Faculty Research and Creative Activities Symposium

No abstract provided.