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A Clean Slate For Texas Foster Youth: Policy Recommendations On Preventing And Resolving Identity Theft For Youth In Foster Care, Madison Howard Churchman

Texas A&M Journal of Property Law

This Article will compare how Texas and other states implement this federal law differently and then discuss how Texas can improve its flawed system to better protect children negatively affected by identity theft. Section II of this Article will introduce and explain M.D. v. Abbott and the changes in Texas foster care on the horizon as a result of this case. Section III will introduce and delve into the issue of identity theft in foster youth as a whole, and it will tell the story of one foster youth who faced the results of identity theft. Finally, the Section breaks …

"Of Mice And Measures": A Project To Improve How We Advance Duchenne Muscular Dystrophy Therapies To The Clinic., Heather Gordish-Dressman, Raffaella Willmann, Laura Dalle Pazze, Arati Kreibich, Maaike Van Putten, Ahlke Heydemann, Laurent P. Bogdanik, Cathleen Lutz, Kay Davies, Alexis R Demonbruen, Dongsheng Duan, David Elsey, So-Ichiro Fukada, Mahasweta Girgenrath, J Patrick Gonzalez, Miranda D Grounds, Andy Nichols, Terry Partridge, Marco Passini, Francesca Sanarica, Frederick J Schnell, Dominic J Wells, Toshifumi Yokota, Courtney S Young, Zhong Zhong, Christopher Spurney, Melissa Spencer, Annamaria De Luca, Kanneboyina Nagaraju, Annemieke Aartsma-Rus

Faculty Research 2018

A new line of dystrophic mdx mice on the DBA/2J (D2) background has emerged as a candidate to study the efficacy of therapeutic approaches for Duchenne muscular dystrophy (DMD). These mice harbor genetic polymorphisms that appear to increase the severity of the dystropathology, with disease modifiers that also occur in DMD patients, making them attractive for efficacy studies and drug development. This workshop aimed at collecting and consolidating available data on the pathological features and the natural history of these new D2/mdx mice, for comparison with classic mdx mice and controls, and to identify gaps in information and their potential …

The Prevalence And Awareness Of Sleep Apnea In Patients Suffering Chronic Pain: An Assessment Using The Stop-Bang Sleep Apnea Questionnaire., Gregory S Tentindo, Scott M Fishman, Chin-Shang Li, Qinlu Wang, Steven D Brass

Articles, Abstracts, and Reports

Purpose: Some patient subsets are at higher risk of sleep apnea, including patients with chronic pain. However, it is unclear whether patients and their caregivers are aware of the possibly increased risk of sleep apnea in this population. Chronic pain is often treated with opioids which may decrease both the central respiratory drive and the patency of the upper airway, potentially contributing to this sleep disorder. Using a self-reporting questionnaire approach in the chronic pain population, this study surveyed patient and caregiver awareness surrounding the risk of sleep apnea. In addition, we looked at the influence of opioid therapy on …

Classification And Outcome Measures For Psoriatic Arthritis., Ying Ying Leung, Alexis Ogdie, Ana-Maria Orbai, William Tillett, Laura C Coates, Vibeke Strand, Philip Mease, Dafna D Gladman

Articles, Abstracts, and Reports

Psoriatic arthritis (PsA) is an inflammatory arthritis with multiple manifestations: peripheral/axial arthritis, enthesitis, dactylitis, psoriasis, and nail involvement. From having an agreed upon classification criteria in 2006, the assessment of PsA has advanced from uncertainties to development and validation of numerous specific outcome measures. The Group for Research and Assessment of Psoriasis and Psoriatic arthritis (GRAPPA) has spearheaded the development of a core domain set and is now working on a core outcome measurement set to standardize outcome measures for PsA, that will provide guidance for use of instruments in randomized controlled trials (RCTs) and longitudinal observational studies (LOS). This …

Myxopapillary Ependymoma With Anaplastic Features: A Case Report With Review Of The Literature., Tridu R Huynh, Conrad Lu, Doniel Drazin, Gregory Lekovic

Articles, Abstracts, and Reports

Background: Myxopapillary ependymoma (MPE) with anaplastic features is extremely rare, with only three case reports in the literature.

Case Description: We report the case of a MPE with anaplastic features in a 24-year-old female who presented with a dominant lumbar mass along with intracranial and sacral metastases. Upon gross total resection of the dominant tumor located at L2-L3, it appeared to arise from the filum terminale, and had a solid component in addition to soft or necrotic areas. Histologically, the tumor was composed of the two classic components of MPE: (1) low-grade ependymal cells surrounding blood vessels, producing the papillary …

Comparative Transcriptomic Analysis Of Human Placentae At Term And Preterm Delivery., Alison G Paquette, Heather M Brockway, Nathan D Price, Louis J Muglia

Articles, Abstracts, and Reports

Preterm birth affects 1 out of every 10 infants in the United States, resulting in substantial neonatal morbidity and mortality. Currently, there are few predictive markers and few treatment options to prevent preterm birth. A healthy, functioning placenta is essential to positive pregnancy outcomes. Previous studies have suggested that placental pathology may play a role in preterm birth etiology. Therefore, we tested the hypothesis that preterm placentae may exhibit unique transcriptomic signatures compared to term samples reflective of their abnormal biology leading to this adverse outcome. We aggregated publicly available placental villous microarray data to generate a preterm and term …

Earle A. Chiles Research Institute 2017 Year In Review, Earle A. Chiles Research Institute

Articles, Abstracts, and Reports

2017 Year in Review for the Earle A. Chiles Research Institute, a division of Providence Cancer Institute at the Robert W. Franz Cancer Center. Year in Review is published annually and highlights translational immunotherapy research from the Earle A. Chiles Research Institute.

A leader in cancer immunotherapy research and innovation since 1993, the Earle A. Chiles Research Institute is a world-class research facility, and home to a team of internationally known scientists and physicians.

4-Year Results From The Rapid-Psa Phase 3 Randomised Placebo-Controlled Trial Of Certolizumab Pegol In Psoriatic Arthritis., Désirée Van Der Heijde, Atul Deodhar, Oliver Fitzgerald, Roy Fleischmann, Dafna Gladman, Alice B Gottlieb, Bengt Hoepken, Lars Bauer, Oscar Irvin-Sellers, Majed Khraishi, Luke Peterson, Anthony Turkiewicz, Jürgen Wollenhaupt, Philip Mease

Articles, Abstracts, and Reports

Objective: To report the efficacy, patient-reported, radiographic and safety outcomes of 4 years' certolizumab pegol (CZP) treatment in patients with psoriatic arthritis (PsA).

Methods: RAPID-PsA (NCT01087788) was double-blind and placebo-controlled to Week 24, dose-blind to Week 48 and open-label (OL) to Week 216. Patients were randomised 1:1:1 to either placebo or CZP 200 mg every 2 weeks (Q2W) or 400 mg every 4 weeks (Q4W) (following 400 mg at Weeks 0/2/4). Patients randomised to CZP continued their assigned dose in the OL period. Patients randomised to placebo were re-randomised to CZP 200 mg Q2W or 400 mg Q4W (post-loading dose) …

Machine-Learning-Based Quantitative Estimation Of Soil Organic Carbon Content By Vis/Nir Spectroscopy, Jianli Ding, Aixia Yang, Jingzhe Wang, Vasit Sagan, Danlin Yu

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Soil organic carbon (SOC) is an important soil property that has profound impact on soil quality and plant growth. With 140 soil samples collected from Ebinur Lake Wetland National Nature Reserve, Xinjiang Uyghur Autonomous Region of China, this research evaluated the feasibility of visible/near infrared (VIS/NIR) spectroscopy data (350-2,500 nm) and simulated EO-1 Hyperion data to estimate SOC in arid wetland regions. Three machine learning algorithms including Ant Colony Optimization-interval Partial Least Squares (ACO-iPLS), Recursive Feature Elimination-Support Vector Machine (RF-SVM), and Random Forest (RF) were employed to select spectral features and further estimate SOC. Results indicated that the feature wavelengths …

Environmental Forensics Study Of Crude Oil And Petroleum Product Spills In Coastal And Oilfield Settings: Combined Insights From Conventional Gc-Ms, Thermodesorption-Gc-Ms And Pyrolysis-Gc-Ms, Michael A. Kruge, José Luis Gallego, Azucena Lara-Gonzalo, Noemi Esquinas

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

A representative set of five oil spill samples from four different regions displayed different product characteristics and different levels of weathering. Three of them were taken along shorelines affected by marine oil spill events, viz., Aboño and Prestige (Spain) and Deepwater Horizon (USA) and the other two were taken at inland oil spill sites (Angola and Kuwait). A multi-faceted environmental forensics approach revealed key molecular features. In addition to the conventional GC/MS analysis of saturated and aromatic fractions, the polar fractions also were analyzed, revealing a complex series of linear alkanones in those oil samples particularly enriched in aliphatics. Thermodesorption-GC-MS …

Simultaneous Use Of Physiological Sensors For A Neuromarketing Task, Charles Descheneaux

Electronic Theses and Dissertations

Physiological measurements have become more popular in Psychological research over the past ten years. These advancements allowed different objective sensors to become another measurement tool in a scientific arsenal of collecting data. Traditionally, performance and after task subjective measures have been used for most studies in Psychological research. With the opportunity to use these subjective measures along with objective measures, more data can be collected during research and therefore potentially produce better quality conclusions. Eye Tracking (ET), functional near infrared (fNIR), transcranial Doppler ultrasound (TCD), electrocardiogram (EKG) and the electroencephalogram (EEG) have shown great promise in their ability to produce …

Simulating Human Pleura Performance In Medical Training Using Measured Tissue Mechanical Properties, Jack Norfleet

Electronic Theses and Dissertations

Medical simulations provide hands-on training at various levels of medical expertise. Yet these simulators fail to accurately mimic the look, feel and behavior of human tissue. Applying measured mechanical properties from human cadaver tissues promises to improve the fidelity of simulated tissue behaviors when subjected to medical procedures. Samples of human parietal pleura were tested under uniaxial tension to failure and measured characteristics were replicated in synthetic pleura. Context specific parameters were then collected and compared between human pleura and the new synthetics. These comparisons tested the hypothesis; H1 Gaps exist between synthetic and human pleura performance, H2: Human tissue …

U.N. Security Council Resolution 1540: An Exemplary Model For A Framework To Safeguard Dangerous Dams Against Sabotage By Nonstate Actors, Ian Andrew Barber

UC Law SF International Law Review

The purpose of this research is to explore how an international framework could be developed in order to safeguard large dams against sabotage by nonstate actors, such as terrorist organizations or hostile civilians. The necessity of an international security agreement to manage dams as a global security threat will be clearly substantiated via an analysis of three determinants: the possible magnitude of dam failure, the inadequacies of international law to regulate asymmetric warfare, and the evolving threat of dam sabotage in the developing world. Subsequently, various legal components and regulatory mechanisms from an existing international agreement will be considered with …

The Developmental And Genetic Basis Of ‘Clubfoot’ In The Peroneal Muscular Atrophy Mutant Mouse, J. Martin Collinson, Nils Lindström, Carlos Neves, Karen Wallace, Caroline Meharg, Rebecca Charles, Zoe Ross, Amy Fraser, Ivan Mbogo, Kadri Oras, Masaru Nakamoto, Simon Barker, Suzanne Duce, Zosia Miedzybrodzka, Neil Vargesson

Biology Faculty Publications

Genetic factors underlying the human limb abnormality congenital talipes equinovarus (‘clubfoot’) remain incompletely understood. The spontaneous autosomal recessive mouse ‘peroneal muscular atrophy’ mutant (PMA) is a faithful morphological model of human clubfoot. In PMA mice, the dorsal (peroneal) branches of the sciatic nerves are absent. In this study, the primary developmental defect was identified as a reduced growth of sciatic nerve lateral motor column (LMC) neurons leading to failure to project to dorsal (peroneal) lower limb muscle blocks. The pma mutation was mapped and a candidate gene encoding LIM-domain kinase 1 (Limk1) identified, which is upregulated in mutant lateral LMC …

Maritime Spatial Planning Supported By Infrastructure For Spatial Information In Europe (Inspire), Andrej Abramic, Emanuele Bigagli, Vittorio Barale, Alberto Lorenzo-Alonso, Conor Norton

Articles

The implementation of Directive 2007/2/EC - INSPIRE can improve and actually strengthen the informationmanagement and data infrastructures needed for setting up Maritime Spatial Planning (MSP) processes. Evidencefor this comes from three parallel analyses: links between the MSP Framework Directive and INSPIRE compo-nents and implementation; the availability of marine and maritime data through the INSPIRE Geo-Portal; andthe adequacy of using an INSPIRE data model for mapping maritime spatial plans. Thefirst item identifiesINSPIRE as a relevant instrument not only for data collection, but additionally for increasing transparency of theMSP processes, using already operational national and European data infrastructure. The marine/maritime dataavailability analysis …

Vegetation Mapping Of A Coastal Dune Complex Using Multispectral Imagery Acquired From An Unmanned Aerial System, C. Suo, Eugene Mcgovern, Alan Gilmer

Conference Papers

Vegetation mapping, identifying the distribution of plant species, is important for analysing vegetation dynamics, quantifying spatial patterns of vegetation evolution, analysing the effects of environment changes on vegetation, and predicting spatial patterns of species diversity. Such analysis can contribute to the development of targeted land management actions that maintain biodiversity and ecological functions. This paper represents a methodology for 3D vegetation mapping of a coastal dune complex using a multispectral camera mounted on an Unmanned Aerial System (UAS) with particular reference to the Buckroney dune complex in Co. Wicklow, Ireland. UAS, also known as Unmanned Aerial Vehicles (UAV’s) or drones, …

Analysis Of The Racial And Ethnic Representation Of Adult Male Inmates In Large Jail Isolation Units In The United States, Lance E. Bohn, Stephen A. Morreale

Walden Faculty and Staff Publications

Black males are overrepresented in US large jails, and this overrepresentation may extend into their isolations units, or DHUs. While overrepresentation in prison populations has been explored and well documented in academic literature. Far less is known about overrepresentation in jail populations where prisoners serve far less time, and in some cases, may not yet be convicted of crimes. The study analyzed the classification of adult male prisoners to DHU within large jails. This central research question of the study primarily focused on exploring the causes and prevalence of overrepresentation in DHUs in jails based on race or ethnicity. The …

Undergraduate Student Catalog 2018-2019, Nova Southeastern University

Undergraduate Programs Course Catalogs

No abstract provided.

Victims Of Nazi Terror In Vienna: Legally Mandated Assistance And Social Democratic Patronage, 1945-48, Matthew P. Berg

2018 Faculty Bibliography

No abstract provided.

Temporal And Geospatial Trends Of Pediatric Cancer Incidence In Nebraska Over A 24-Year Period, Evi A. Farazi, Shinobu Watanabe-Galloway, L. Westman, B. Rettig, P. Hunt, R. Cammack, John W. Sparks, Don W. Coulter

Journal Articles: Epidemiology

BACKGROUND: Data from the Surveillance, Epidemiology, and End Results (SEER) revealed that the incidence of pediatric cancer in Nebraska exceeded the national average during 2009-2013. Further investigation could help understand these patterns.

METHODS: This retrospective cohort study investigated pediatric cancer (0-19 years old) age adjusted incidence rates (AAR) in Nebraska using the Nebraska Cancer Registry. SEER AARs were also calculated as a proxy for pediatric cancer incidence in the United States (1990-2013) and compared to the Nebraska data. Geographic Information System (GIS) mapping was also used to display the spatial distribution of cancer in Nebraska at the county level. Finally, …

The Enzymatic Activity Of Apobe3g Multimers, Yangang Pan, Karen Zagorski, Luda S. Shlyakhtenko, Yuri L. Lyubchenko

Journal Articles: Pharmaceutical Sciences

APOBEC3G (A3G) belongs to the family of cytosine deaminases that play an important role in the innate immune response. Similar to other, two-domain members of the APOBEC family, A3G is prone to concentration-dependent oligomerization, which is an integral for its function in the cell. It is shown that oligomerization of A3G is related to the packing mechanism into virus particle and, is critical for the so-called roadblock model during reverse transcription of proviral ssDNA. The role of oligomerization for deaminase activity of A3G is widely discussed in the literature; however, its relevance to deaminase activity for different oligomeric forms of …

Microstructure-Guided Numerical Simulations To Predict The Thermal Performance Of A Hierarchical Cement-Based Composite Material, Sumanta Das, Matthew Aguayo, Subramaniam D. Rajan, Gaurav Sant, Narayanan Neithalath

Civil & Environmental Engineering Faculty Publications

This paper presents a microstructure-guided numerical homogenization technique to predict the effective thermal conductivity of a hierarchical cement-based material containing phase change material (PCM)-impregnated lightweight aggregates (LWA). Porous inclusions such as LWAs embedded in a cementitious matrix are filled with multiple fluid phases including PCM to obtain desirable thermal properties for building and infrastructure applications. Simulations are carried out on realistic three-dimensional microstructures generated using pore structure information. An inverse analysis procedure is used to extract the intrinsic thermal properties of those microstructural components for which data is not available. The homogenized heat flux is predicted for an imposed temperature …

Quantifying Site-Level Usage And Certainty Of Absence For An Invasive Species Through Occupancy Analysis Of Camera-Trap Data, Amy J. Davis, Ryan Mccreary, Jeremiah Psiropoulos, Gary Brennan, Terry Cox, Andrew Partin, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Copyright Springer International Publishing

This document is a U.S. government work and is not subject to copyright in the United States.

https://doi.org/10.1007/s10530-017-1579-x

A Review Of Classical Swine Fever Virus And Routes Of Introduction Into The United States And The Potential For Virus Establishment, Vienna R. Brown, Sarah N. Bevins

United States Department of Agriculture Wildlife Services: Staff Publications

Classical swine fever (CSF) is caused by CSF virus (CSFV) which can be the source of substantial morbidity and mortality events in affected swine. The disease can take one of several forms (acute, chronic, or prenatal) and depending on the virulence of the inoculating strain may result in a lethal infection irrespective of the form acquired. Because of the disease-free status of the United States and the high cost of a viral incursion, a summary of US vulnerabilities for viral introduction and persistence is provided. The legal importation of live animals as well as animal products, byproducts, and animal feed …

Diets Of Kauai’S Invasive Rose-Ringed Parakeet (Psittacula Krameri): Evidence Of Seed Predation And Dispersal In A Human-Altered Landscape, Aaron B. Shiels, William P. Bukoski, Shane R. Siers

United States Department of Agriculture Wildlife Services: Staff Publications

Rose-ringed parakeets (Psittacula krameri) are the world’s most successful introduced parrots, and[2000 individuals reside on Kauai, Hawaii. These birds destroy crops, but impacts to other native and non-native species are largely unknown. Our study objectives on Kauai were to determine: (1) diets of rose-ringed parakeets at five sites (n = 9–25 per site), by sex, through crop and gizzard analysis and carbon and nitrogen stable isotope analysis, and (2) whether birds are dispersing or depredating seeds. We found 100% of birds (n = 64) were eating plant material and 80% of their diet was seed; males …

Assessing Owl Collisions With Us Civil And Us Air Force Aircraft, Kimberly E. Linnell, Brian E. Washburn

United States Department of Agriculture Wildlife Services: Staff Publications

Collisions between wildlife and aircraft (wildlife strikes) pose notable risks. Previous research has found that a variety of birds and mammals are involved in wildlife strikes, but no comprehensive evaluation of collisions between owl and aircraft (owl strikes) has been conducted. We queried the Federal Aviation Administration’s National Wildlife Strike Database (from 1 January 1990 to 30 June 2014) and the US Air Force’s Birdstrike Database (from 1 January 1994 to 30 June 2014) to characterize owl strikes. We found 2531 owl strikes involving at least 20 species of owls. Barn Owls (Tyto alba) were the most frequently …

Dadless: Dead Dads In Hamlet And The Effects On Their Children, Erin Diiorio

Student and Faculty Research Days

This research is a close look at the methods of grief as depicted by the children who lose their fathers in William Shakespeare’s classic, Hamlet. The goal is to track each child’s reaction to the sudden bereavement in a variety of physical and emotional manifestations. This has been done by first examining current literature on the text, followed by a review of historical context of the period in which the play was written, and finally analyzing each character’s behavior. In doing so, this research seeks to highlight the importance of the presence of fathers within Hamlet and provide insight …

Longitudinal Outcomes Of Youth Who Age Out Of Foster Care, Tegan Lesperance

Wayne State University Dissertations

LONGITUDINAL OUTCOMES OF YOUTH WHO AGE OUT OF FOSTER CARE

by

TEGAN LESPERANCE

May 2018

Advisor: Dr. Paul Toro

Major: Psychology (Clinical)

Degree: Doctor of Philosophy

Each year in America, between 20,000 and 30,000 youths reach an age, typically 18 years, when they must exit the foster care system due to age restrictions, in a process referred to as aging out (U. S. Department of Health and Human Services, 2016). These youths disproportionately experience a host of negative outcomes, including high rates of homelessness and precarious housing, high levels of psychological distress and victimization, increased risk of substance abuse, lower …

Progress Toward Controlled Disulfide Formation To Access Neuroactive Conotoxins, Thilini Kondasinghe

Wayne State University Dissertations

"Conotoxins are mini proteins isolated from marine snails of the Conus family. They have shown activity in the selective inhibition of various ion channels. Therefore, they present an opportunity as possible therapy for a myriad of neurological ailments. The synthesis of conotoxins would enable both biological studies and evaluation of these structures as lead targets for therapeutics. However, establishing a reliable method to consistently folding disulfide rich proteins, including conotoxin, into their native structure has been challenging over few decades. In this research project, it is shown the progress towards a mild, efficient, and broadly applicable methods to generate the …

Carbohydrate-Based Inducers Of Cellular Stress For Targeting Cancer Cell Metabolism, Fidelis Ndombera

Wayne State University Dissertations

ABSTRACT

CARBOHYDRATE-BASED INDUCERS OF CELLULAR STRESS FOR TARGETING CANCER CELL METABOLISM

by

FIDELIS TOLOYI NDOMBERA

May 2018

Advisor: Dr. Young-Hoon Ahn

Major: Chemistry (Biochemistry)

Degree: Doctor of Philosophy

Metabolic reprogramming and redox control of cancer cells is vital for their proliferation, but also provides selective strategies for treating cancer. Increased generation of reactive oxygen species (ROS) and an intricate control of redox status in cancer cells relative to normal cells provide a basis for designing ROS-inducing anticancer agents. In my work, I designed, synthesized and evaluated carbohydrate-based small molecules for ROS-generation, cytotoxicity and redox signaling and stress response. Our data …