Digital Commons Network^™

Suffolk Journal, Vol.82, No.10, 12/05/2018, Suffolk Journal

Suffolk Journal

No abstract provided.

Advances In Processing, Mining, And Learning Complex Data: From Foundations To Real-World Applications, Jia Wu, Shirui Pan, Chuan Zhou, Gang Li, Wu He, Chengqi Zhang

Information Technology & Decision Sciences Faculty Publications

Processing, mining, and learning complex data refer to an advanced study area of data mining and knowledge discovery concerning the development and analysis of approaches for discovering patterns and learning models from data with a complex structure (e.g., multirelational data, XML data, text data, image data, time series, sequences, graphs, streaming data, and trees) [1–5]. These kinds of data are commonly encountered in many social, economic, scientific, and engineering applications. Complex data pose new challenges for current research in data mining and knowledge discovery as they require new methods for processing, mining, and learning them. Traditional …

De-Extinction And The Conception Of Species, Leonard Finkelman

Faculty Publications

Developments in genetic engineering may soon allow biologists to clone organisms from extinct species. The process, dubbed “de-extinction,” has been publicized as a means to bring extinct species back to life. For theorists and philosophers of biology, the process also suggests a thought experiment for the ongoing “species problem”: given a species concept, would a clone be classified in the extinct species? Previous analyses have answered this question in the context of specific de-extinction technologies or particular species concepts. The thought experiment is given more comprehensive treatment here. Given the products of three de-extinction technologies, twenty-two species concepts are “tested” …

Modeling The Disappearance Of The Neanderthals Using Concepts Of Population Dynamics And Ecology, Michael F. Roberts, Stephen E. Bricher

Faculty Publications

Current hypotheses regarding the disappearance of Neanderthals (NEA) in Europe fall into two main categories: climate change, and competition. Here we review current research and existing mathematical models that deal with this question, and we propose an approach that incorporates and permits the investigation of the current hypotheses. We have developed a set of differential equations that model population dynamics of anatomically modern humans (AMH) and NEA, their ecological relations to prey species, and their mutual interactions. The model allows investigators to explore each of the two main categories or combinations of both, as well as various forms of competition …

Uab Magazine - Fall 2018, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

An Investigation Into Tetrodotoxin (Ttx) Levels Associated With The Red Dorsal Spots In Eastern Newt (Notophthalmus Viridescens) Efts And Adults, Mackenzie M. Spicer, Amber N. Stokes, Trevor L. Chapman, Edmund D. Brodie, Edmund D. Brodia, Brian G. Gall

ETSU Faculty Works

We investigated the concentration of tetrodotoxin (TTX) in sections of skin containing and lacking red dorsal spots in both Eastern newt (Notophthalmus viridescens) efts and adults. Several other species, such as Pleurodeles waltl and Echinotriton andersoni, have granular glands concentrated in brightly pigmented regions on the dorsum, and thus we hypothesized that the red dorsal spots of Eastern newts may also possess higher levels of TTX than the surrounding skin. We found no difference between the concentrations of TTX in the red spots as compared to neighboring skin lacking these spots in either efts or adults. However, efts with more …

Cross-Species Analysis Of Apical Asparagine-Rich Protein Of Plasmodium Vivax And Plasmodium Knowlesi, F. Muh, M.A. Ahmed, J.H. Han, M.H. Nyunt, S.K. Lee, Y.L. Lau, O. Kaneko, E.T. Han

Research Publications (2016 to 2020)

The Plasmodium falciparum apical asparagine (Asn)-rich protein (AARP) is one of malarial proteins, and it has been studied as a candidate of malaria subunit vaccine. Basic characterization of PvAARP has been performed with a focus on its immunogenicity and localization. In this study, we further analyzed the immunogenicity of PvAARP, focusing on the longevity of the antibody response, cross-species immunity and invasion inhibitory activity by using the primate malaria parasite Plasmodium knowlesi. We found that vivax malaria patient sera retained anti-PvAARP antibodies for at least one year without re-infection. Recombinant PvAARP protein was strongly recognized by knowlesi malaria patients. Antibody …

Accumulation Of Terpenoid Indole Alkaloids In Jasmonic Acid Elicited Catharanthus Roseus Plants Before And During Flowering, Qi Fang Pan, Mohd Zuwairi Saiman, Robert Verpoorte, Kexuan Tang

Research Publications (2016 to 2020)

Jasmonates analogues including jasmonic acid (JA) and methyl-jasmonate (MeJA) are plant-signaling molecules involved in defense against insects and pathogens. In Catharanthus roseus, jasmonates play a key role in regulating the biosynthesis of pharmaceutically important terpenoid indole alkaloids (TIAs). In the present study, C. roseus plants were elicited with JA before and during flowering to investigate the induction of TIA biosynthesis in different organs during the two developmental stages concerning via HPLC and qRT-PCR methods. The results showed that JA stimulates the TIA accumulation before flowering but had less effect during flowering. TIA accumulations in different organs (flower, leaf, and root) …

Cytokine And Chemokine Profiling In Patients With Hand, Foot And Mouth Disease In Singapore And Malaysia, F.M.S. Teo, M. Nyo, A.A. Wong, N.W.H. Tan, M.T. Koh, Y.F. Chan, C.Y. Chong, J.J.H. Chu

Research Publications (2016 to 2020)

Hand, foot and mouth disease (HFMD) is a prevalent contagious childhood disease typically associated with fever, oral lesions and limb exanthema. While HFMD is caused by a plethora of serotypes of viruses under the genus Enterovirus within the Picornaviridae family, Coxsackievirus A16 (CV-A16) and Enterovirus 71 (EV-A71) are considered the main etiological agents. In recent years however, other viruses have also been isolated in considerable numbers from infected individuals in many regions, joining the legion commonly associated with HFMD. The present study investigated the cytokine and chemokine profiles of HFMD patients from Singapore and Malaysia for the first time. Comparative …

Electronic Properties Of Synthetic Shrimp Pathogens-Derived Dna Schottky Diodes, Nastaran Rizan, Yen Yew Chan, Maryam Rajabpour Niknam, Jegenathan Krishnasamy, Subha Bhassu, Zee Hong Goh, Sridevi Devadas, Mohamed Shariff Mohd Din, Hairul Anuar Tajuddin, Rofina Yasmin Othman, Siew Moi Phang, M. Iwamoto, Vengadesh Periasamy

Research Publications (2016 to 2020)

The exciting discovery of the semiconducting-like properties of deoxyribonucleic acid (DNA) and its potential applications in molecular genetics and diagnostics in recent times has resulted in a paradigm shift in biophysics research. Recent studies in our laboratory provide a platform towards detecting charge transfer mechanism and understanding the electronic properties of DNA based on the sequence-specific electronic response, which can be applied as an alternative to identify or detect DNA. In this study, we demonstrate a novel method for identification of DNA from different shrimp viruses and bacteria using electronic properties of DNA obtained from both negative and positive bias …

Metabolomic Analysis Of Low And High Biofilm-Forming Helicobacter Pylori Strains, E.H.J. Wong, C.G. Ng, K.L. Goh, J. Vadivelu, B. Ho, M.F. Loke

Research Publications (2016 to 2020)

The biofilm-forming-capability of Helicobacter pylori has been suggested to be among factors influencing treatment outcome. However, H. pylori exhibit strain-to-strain differences in biofilm-forming-capability. Metabolomics enables the inference of spatial and temporal changes of metabolic activities during biofilm formation. Our study seeks to examine the differences in metabolome of low and high biofilm-formers using the metabolomic approach. Eight H. pylori clinical strains with different biofilm-forming-capability were chosen for metabolomic analysis. Bacterial metabolites were extracted using Bligh and Dyer method and analyzed by Liquid Chromatography/Quadrupole Time-of-Flight mass spectrometry. The data was processed and analyzed using the MassHunter Qualitative Analysis and the Mass …

Relationship Dimension In University Laboratories And Its Effects On Students’ Interest, Atiqurrahman Rosdi, Zul Ilham, Suzana Ariff Azizan, Mohd Zulkefeli, Shaikh Mohd Saifuddeen

Research Publications (2016 to 2020)

Malaysian universities are currently facing a decline of students’ interest in science. It is perceived that the students’ practices in laboratory activities with properly managed activities could result in positive interest in science. In that sense, it is argued that laboratory activities are less constrained, creating excellent opportunities for the interaction between instructor and students to occur. Hence, this study was aimed to examine the relationship dimension in university laboratories and its’ connection towards the students’ interest in a science subject. Drawing upon a survey conducted over 321 science students in four Malaysian Universities, a series of exploratory factorial, descriptive …

Sustainable Syntheses Of (−)-Jerantinines A & E And Structural Characterisation Of The Jerantinine-Tubulin Complex At The Colchicine Binding Site, C.J. Smedley, P.A. Stanley, M.E. Qazzaz, A.E. Prota, N. Olieric, H. Collins, H. Eastman, A.S. Barrow, K.H. Lim, T.S. Kam, B.J. Smith, H.M. Duivenvoorden, B.S. Parker, T.D. Bradshaw, M.O. Steinmetz, J.E. Moses

Research Publications (2016 to 2020)

The jerantinine family of Aspidosperma indole alkaloids from Tabernaemontana corymbosa are potent microtubule-Targeting agents with broad spectrum anticancer activity. The natural supply of these precious metabolites has been significantly disrupted due to the inclusion of T. corymbosa on the endangered list of threatened species by the International Union for Conservation of Nature. This report describes the asymmetric syntheses of (-)-jerantinines A and E from sustainably sourced (-)-Tabersonine, using a straight-forward and robust biomimetic approach. Biological investigations of synthetic (-)-jerantinine A, along with molecular modelling and X-ray crystallography studies of the tubulin-(-)-jerantinine B acetate complex, advocate an anticancer mode of action …

Office Of The Vice Provost For Research Annual Report - 2018, Office Of The Vice Provost For Research, East Tennessee State University

Annual Reports

No abstract provided.

2018 Spring - University School Alumni Newsletter, University School, East Tennessee State University

University School Newsletters

No abstract provided.

Using Family Connections To Create Community Connections: How A Genealogy Fair Can Benefit The Community And The Library, Deedee Baldwin, Jennifer Mcgillan, Corinne Kennedy

UL Publications

The Mississippi State University Libraries Genealogy Fair was founded to assist Mississippians with developing research skills, to encourage genealogists to use resources held by the Libraries, and to create community connections that would support donations of historical material to the Libraries.

Bilayer Thickness And Curvature Influence Binding And Insertion Of A Phlip® Peptide, Alexander G. Karabadzhak, Dhammika Weerkkody, John Deacon, Oleg A. Andreev, Yana K. Reshetnyak, Donald Engelman

Physics Faculty Publications

The physical properties of lipid bilayers, such as curvature and fluidity, can affect the interactions of polypeptides with membranes, influencing biological events. Additionally, given the growing interest in peptide-based therapeutics, understanding the influence of membrane properties on membrane-associated peptides has potential utility. pH low insertion peptides (pHLIPs) are a family of water-soluble peptides that can insert across cell membranes in a pH-dependent manner, enabling the use of pH to follow peptide-lipid interactions. Here we study pHLIP interactions with liposomes varying in size and composition, to determine the influence of several key membrane physical properties. We find that pHLIP binding to …

Rollins Magazine, Spring 2018, Rollins College Office Of Marketing And Communications

Rollins Magazine

No abstract provided.

Performance Analysis Of A Direct Injection Diesel Engine Using Biodiesel And Additives, Zul Ilham

Research Publications (2016 to 2020)

No abstract provided.

Volleyball Program 2018: Winona State University, Winona State University

Volleyball Programs

A 2018 program proof for the Winona State University (WSU) Women's Volleyball team.

Volleyball Program 2018: Winona State University, Winona State University

Volleyball Programs

A 2018 program for the Winona State University (WSU) Women's Volleyball team.

Gpr56/Adgrg1 Regulates Development And Maintenance Of Peripheral Myelin, Sarah D. Ackerman, Amit Mogha, Breanne L. Harty, Mitchell D'Rozario, Nicholas E. Sanchez, Paul Gamble, Matthew R. Macewan, Wilson Zachary Ray, Kelly R. Monk, Et Al

Open Access Publications

No abstract provided.

Antenatal Spontaneous Renal Forniceal Rupture Presenting As An Acute Abdomen, Jennifer Travieso, Omar M. Young

Open Access Publications

No abstract provided.

Construction, Expression, And Characterization Of Rsea-Egf And In Vitro Evaluation Of Its Antitumor Activity Against Nasopharyngeal Cancer, Xueting Liu, Liping Zeng, Zhongqiu Zhou, Yang Xie, Shan Wang, Junyan Zhang, Ying He, Zehong Zou, Jianguo Zhang, Ailin Tao

Open Access Publications

No abstract provided.

Synthesis And Evaluation Of Troponoids As A New Class Of Antibiotics, Feng Cao, Cari Orth, Maureen J. Donlin, Patrick Adegboyega, Marvin J. Meyers, Ryan P. Murelli, Mohamed Elagawany, Bahaa Elgendy, John E. Tavis

Open Access Publications

No abstract provided.

The Toxoplasma Gondii Active Serine Hydrolase 4 Regulates Parasite Division And Intravacuolar Parasite Architecture, Ian T. Foe, Ouma Onguka, Katherine Amberg-Johnson, Rikki M. Garner, Neri Amara, Wandy Beatty, Ellen Yeh, Matthew Bogyo

Open Access Publications

No abstract provided.

Existence Of Solution For Some Two-Point Boundary Value Fractional Differential Equations, Kenneth Ifeanyi Isife

Turkish Journal of Mathematics

Using a fixed point theorem, we establish the existence of a solution for a class of boundary value fractional differential equation. Secondly, we will adopt the method of successive approximations to obtain an approximate solution to our problem. Furthermore, using the Laplace transform technique, an explicit solution to a particular case of our problem is obtained. Finally, some examples are given to illustrate our results.

Nebraska Grazing Conference Proceedings, 2018, Center For Grassland Studies, University Of Nebraska-Lincoln

Nebraska Grazing Conference Proceedings

Pasture Monitoring Sesion

Overview of Choquette Ranch by Jim Choquette

Field Applications of Pasture and Ecological Monitoring by Christine Su

Keeping Human Knowledge at the Center of Technology by Christine Su

Field Monitoring Exercise with Christine Su, Jim O’Rourke, Bethany Johnston, Brad Schick, Brent Plugge, Ben Beckman, and Jace Stott

Prescribed Fire, Bird Monitoring, and Butterfly Date by Andrew Pierson

Strategies for Rangeland Monitoring by Jim O’Rourke

Pasture Monitoring: Field Experience by Jeff Nichols, Beau Mathewson, and Mitch Stephenson

Ranch Succession Planning Session

Keeping Your Ranching Operation in the Family for Future Generations by Ron Hanson

Sharing Our Ranch Succession …

Structural Change In State Postconviction Review, Lee Kovarsky

Notre Dame Law Review

This Article's ultimate objectives are to diagnose, predict, and evaluate structural change in State PCR. Because claims and evidence necessary to enforce constitutional rights increasingly require a meaningful collateral forum, and because the federal collateral forum is so limited, State PCR is, for lack of a better term, the Last Man Standing. That status is not lost on the Supreme Court and lower federal judges, who are adapting available legal rules to try to improve the efficacy of collateral process in state court. And such adaptation does add to the bite of criminal-process rights, the underenforcement of which is perceived …

Michigan's Religious Exemption For Faith-Based Adoption Agencies: State-Sanctioned Discrimination Or Guardian Of Religious Liberty?, Allison L. Mcqueen

Notre Dame Law Review

Historically, most of the legal obstacles faced by gay couples hoping to expand their families through adoption stemmed from prohibitions on marriage. That was until Obergefell. Barriers to same-sex adoption have been steadily falling over the past decade, and, in the wake of the Supreme Court’s decision, married couples are now able to adopt in every state. However, there remains one pressing barrier to adoption for same-sex couples: “conscience clause” adoption laws enacted to allow faith-based adoption agencies to turn away prospective parents whose sexuality conflicts with their “sincerely held religious beliefs.” Though Ms. DeBoer and Ms. Rowse successfully broke …