Digital Commons Network^™

Surgical Interventions For Advanced Parameningeal Rhabdomyosarcoma Of Children And Adolescents., Paul J Choi, Joe Iwanaga, R Shane Tubbs, Emre Yilmaz

Articles, Abstracts, and Reports

Owing to its rarity, rhabdomyosarcoma of the head and neck (HNRMS) has seldom been discussed in the literature. As most of the data is based only on the retrospective experiences of tertiary healthcare centers, there are difficulties in formulating a standard treatment protocol. Moreover, the disease is poorly understood at its pathological, genetic, and molecular levels. For instance, 20% of all histological assessment is inaccurate; even an experienced pathologist can confuse rhabdomyosarcoma (RMS) with neuroblastoma, Ewing's sarcoma, and lymphoma. RMS can occur sporadically or in association with genetic syndromes associated with predisposition to other cancers such as Li-Fraumeni syndrome and …

Daily Eastern News: January 09, 2018, Eastern Illinois University

January

No abstract provided.

A New Toolset For Protein Expression And Subcellular Localization Studies In Citrus And Its Application To Citrus Tristeza Virus Proteins, Amit Levy, Choaa El-Mochtar, Chunxia Wang, Michael M. Goodin, Vladimir Orbovic

Plant Pathology Faculty Publications

Background

Transient gene expression is a powerful tool to study gene function in plants. In citrus, Agrobacterium transformation is the method of choice for transient expression studies, but this method does not work efficiently with many gene constructs, and there is a need for a more robust transient expression system in citrus leaves. Biolistic particle delivery is an alternative to Agrobacterium transformation, and in some plants, such as Arabidopsis, gives higher transformation rates in leaf tissues than Agrobacterium.

Results

Here we describe an improved method for gene expression in epidermal cells of citrus leaves, using the Bio-Rad Helios gene-gun. …

The Influence Of Personal Well-Being On Learning Achievement In University Students Over Time: Mediating Or Moderating Effects Of Internal And External University Engagement, Lu Yu, Daniel T. L. Shek, Xiaoqin Zhu

Pediatrics Faculty Publications

The current study examined the relationship between students' personal well-being and their learning achievement during university study, and whether such relationship would be mediated or moderated by university engagement. A total of 434 university students from one public university in Hong Kong participated in the study. The participants completed an online survey consisting of personal well-being (cognitive behavioral competence and general positive youth development), university engagement, and learning achievement measures (personal growth, and accumulated GPA as academic achievement) at four time points with a 1-year interval. Results showed that personal well-being measured at the beginning of university study positively predicted …

A Plasma Telomeric Cell-Free Dna Level In Unaffected Women With Brca1 Or/And Brca2 Mutations: A Pilot Study, Shatovisha Dey, Natascia Marino, Kanokwan Bishop, Paige N. Dahlgren, Aditi Shendre, Anna Maria Storniolo, Chunyan He, Hiromi Tanaka

Internal Medicine Faculty Publications

Plasma cell-free DNA (cfDNA) is a small DNA fragment circulating in the bloodstream originating from both non-tumor- and tumor-derived cells. A previous study showed that a plasma telomeric cfDNA level decreases in sporadic breast cancer patients compared to controls. Tumor suppressor gene products including BRCA1 and BRCA2 (BRCA1&2) play an important role in telomere maintenance. In this study, we hypothesized that the plasma telomeric cfDNA level is associated with the mutation status of BRCA1&2 genes. To test this hypothesis, we performed plasma telomeric cfDNA quantitative PCR (qPCR)-based assays to compare 28 women carriers of the BRCA1&2 mutation with age-matched controls …

Exploration Of The Germline Genome Of The Ciliate Chilodonella Uncinata Through Single-Cell Omics (Transcriptomics And Genomics), Xyrus X. Maurer-Alcalá, Rob Knight, Laura A. Katz

Biological Sciences: Faculty Publications

Separate germline and somatic genomes are found in numerous lineages across the eukaryotic tree of life, often separated into distinct tissues (e.g., in plants, animals, and fungi) or distinct nuclei sharing a common cytoplasm (e.g., in ciliates and some foraminifera). In ciliates, germline-limited (i.e., micronuclear-specific) DNA is eliminated during the development of a new somatic (i.e., macronuclear) genome in a process that is tightly linked to large-scale genome rearrangements, such as deletions and reordering of protein-coding sequences. Most studies of germline genome architecture in ciliates have focused on the model ciliates Oxytricha trifallax, Paramecium tetraurelia, and Tetrahymena thermophila, for which …

Benefit Of Intensity Modulated Bolus Electron Conformal Therapy For Post Mastectomy Chest Wall Irradiation, John Doiron

LSU Master's Theses

Purpose: The delivery of post-mastectomy radiotherapy (PMRT) with bolus electron conformal therapy (BECT) for patients with left-sided breast cancer can reduce second cancer complication probability (SCCP) compared to modern rotational intensity modulated x-ray (IMXT) techniques such as volumetric modulated arc therapy (VMAT) or Tomotherapy. However, rotational IMXT yields superior levels of dose homogeneity compared to BECT. This study investigates the use of intensity modulated (IM) BECT (IM-BECT) to improve dose homogeneity in the chest wall (CW) region of the PMRT planning target volume (PTV) abutted to parallel opposed IMXT tangents for the remaining PTV for a clinically-representative set of patients, …

Efek Produk Galohgor Terhadap Aktivitas Antioksidan Dan Penurunan Stres Oksidatif Diabetes Melitus Tipe 2, Sulasyi Setyaningsih, Roosita Katrin, Evy Damayanthi

Media Kesehatan Masyarakat Indonesia

Hiperglikemi kronis pada penderita diabetes melitus tipe 2 meningkatkan terbentuknya radikal bebas yang disebabkan peningkatan peroksidasi asam lemak, yang akan mengarah pada komplikasi yang bersifat kronis. Peningkatan terbentuknya radikal bebas yang tidak diimbangi dengan peningkatan asupan antioksidan akan menimbulkan stres oksidatif. Penelitian dilakukan untuk menganalisis efek pemberian produk galohgor berupa cookies dan minuman serbuk terhadap status antioksidan dan penurunan penanda stres oksidatif pada penderita DM tipe 2. Sebanyak 18 subjek penderita DM tipe 2 dibagi menjadi 2 kelompok, yaitu kelompok intervensi (n=9) diberikan cookies dan minuman serbuk galohgor dan kelompok kontrol (n=9) diberi cookies dan minuman serbuk yang tidak mengandung …

Characterizing Cdom Spectral Variability Across Diverse Regions And Spectral Ranges, Brice K. Grunert, Colleen B. Mouw, Audrey B. Ciochetto

Graduate School of Oceanography Faculty Publications

Satellite remote sensing of colored dissolved organic matter (CDOM) has focused on CDOM absorption (a_CDOM) at a reference wavelength, as its magnitude provides insight into the underwater light field and large-scale biogeochemical processes. CDOM spectral slope, S_CDOM, has been treated as a constant or semiconstant parameter in satellite retrievals of a_CDOM despite significant regional and temporal variabilities. S_CDOM and other optical metrics provide insights into CDOM composition, processing, food web dynamics, and carbon cycling. To date, much of this work relies on fluorescence techniques or a_CDOM in spectral ranges unavailable to current …

Plexin-B1 Signaling In Contact Inhibition Of Locomotion Between Osteoclasts And Osteoblasts, Abhijit Deb Roy

Doctoral Dissertations

Bone remodeling is critical for maintenance of bone health and requires a balance of bone resorption by osteoclasts followed with formation by osteoblasts. These opposing activities are spatially and temporally segregated and coordinated on the bone surface. Chemoattraction between osteoclasts and osteoblasts has been extensively investigated and has been proposed to direct osteoblasts to the site of bone resorption. However, the mechanism by which osteoclasts and osteoblasts are spatially segregated on the bone surface remains unknown. In this thesis, I demonstrate that osteoclasts induce contact inhibition of locomotion in migrating osteoblasts, which may enable spatial segregation of these cells. I …

Characterization Of The Transcriptional Elongation Factor Ell3 In B Cells And Its Role In B-Cell Lymphoma Proliferation And Survival, Lou-Ella M.M. Alexander

USF Tampa Graduate Theses and Dissertations

The studies presented in this dissertation establish the dynamics of Eleven nineteen Lysine-rich leukemia (ELL) family of elongation factors during B cell differentiation and provide a description of ELL3 function in B cells.

The transition from a mature naïve B cells into an activated B cell is dependent on a large increase in transcriptional output, which is followed by focused expression on secreted immunoglobulin upon terminal differentiation into plasma cell. While ELL family members have previously been implicated in alternative splicing at the immunoglobulin heavy chain locus in plasma cells, their presence and function prior to differentiation is currently not …

Model Prediksi Pengendalian Komplikasi Penyakit Penyerta Pada Pengguna Narkotika Di Palembang, Rico Januar Sitorus, Feranita Utama, Imelda G. Purba, Bina Melvina

Media Kesehatan Masyarakat Indonesia

Penyalahgunaan narkotika dapat mengakibatkan komplikasi fisik, psikologis dan beban ekonomi keluarga. Semakin lama menggunakan narkotika dan tidak menjalani rehabilitasi akan membuat kecanduan yang berat. Pengguna narkotika dengan adiksi berat akan berdampak juga terhadap beratnya penyakit yang dialami dan lamanya menjalani rehabilitasi. Beban penyakit yang diakibatkan ketergantungan narkotika akan berdampak terhadap kondisi sosial ekonomi sendiri dan keluarga. Penelitian ini bertujuan untuk menghasilkan suatu model prediksi terhadap pengendalian komplikasi penyakit penyerta pengguna narkotika. Desain penelitian ini adalah cross sectional study dengan populasi penelitian adalah semua pengguna narkotika baik pengguna narkotika suntik dan narkotika bukan suntik. Sampel dalam penelitian ini adalah pecandu narkotika …

Hubungan Antara Fleksibilitas Dan Kekuatan Otot Lengan Dengan Kecepatan Renang, Djohan Aras, Abdullah Arsyad, Nurhikmawaty Hasbiah

Media Kesehatan Masyarakat Indonesia

Kecepatan adalah aset utama atlet renang. Penelitian terbaru menunjukkan variabel fleksibilitas dan kekuatan otot lengan sangat memengaruhi kecepatan renang individu. Penelitian ini bertujuan mengetahui hubungan antara fleksibilitas dan kekuatan otot lengan pada atlet renang gaya bebas di Makassar. Desain penelitian ini adalah cross sectional dengan jumlah sampel 20 orang atlet yang berusia 12-18 tahun. Variabel independen yang diukur adalah fleksibilitas dan kekuatan otot lengan. Variabel dependen yang diukur adalah kecepatan renang melalui tes renang gaya bebas 25 meter. Analisis bivariat digunakan untuk menganalisis hubungan fleksibilitas dan kekuatan otot lengan dengan kecepatan pada atlet renang. Hasil penelitian menunjukkan adanya korelasi positif …

Intervensi Susu Tinggi Protein Terhadap Tingkat Konsumsi Zat Gizi Makro Dan Status Gizi Pada Kelompok Usia Dewasa, Harna Harna, Clara M. Kusharto, Katrin Roosita

Media Kesehatan Masyarakat Indonesia

Susu tinggi protein merupakan makanan kompleks yang mengandung beberapa senyawa bioaktif potensial, kemungkinan memiliki efek terhadap berat badan. Tujuan penelitian adalah untuk menganalisis pengaruh pemberian susu tinggi protein terhadap tingkat konsumsi susu tinggi protein, status gizi dan menganalisis hubungan antara tingkat konsumsi zat gizi makro dengan status gizi. Penelitian ini menggunakan metode eksprimental dengan desain Randomized Control Trial (RCT). Subjek dibagi menjadi dua kelompok yaitu 24 subjek pada kelompok perlakuan dan 23 subjek pada kelompok kontrol. Kelompok perlakuan diberikan susu tinggi protein dan pendidikan gizi selama 90 hari. Kelompok kontrol diberikan pendidikan gizi. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan …

Perilaku Petani Penyemprot Yang Berhubungan Dengan Kadar Serum Cholinesterase, Devi Ayu Susilowati, Suhartono Suhartono, Bagoes Widjanarko, Mateus Sakundarno Adi, Suratman Suratman

Media Kesehatan Masyarakat Indonesia

Petani penyemprot merupakan salah satu populasi berisiko untuk mengalami keracunan pestisida akibat dari aktivitas pertanian yang sangat dekat dengan pestisida. Untuk mengetahui adanya paparan pestisida dan penilaian risiko keracunan pestisida adalah dengan pengukuran kadar serum cholinesterase. Tujuan penelitian ini adalah membuktikan hubungan antara pengetahuan, perilaku merokok ketika menyemprot, dan kelengkapan Alat Pelindung Diri (APD) ketika menyemprot dengan kadar serum cholinesterase pada petani penyemprot. Jenis penelitian ini observasional dengan desain studi cross sectional. Jumlah sampel 88 petani penyemprot di Desa Dukuhlo Kabupaten Brebes. Sampel diambil dengan teknik acak sederhana. Hasil analisis multivariat dengan multipel regresi logistik menunjukkan bahwa faktor …

Mechanisms And Identification Of Unsteady Separation Development And Remediation, Matthew Scott Melius

Dissertations and Theses

Unsteady flow separation represents a highly complex and important area of study within fluid mechanics. The extent of separation and specific time scales over which it occurs are not fully understood and has significant consequences in numerous industrial applications such as helicopters, jet engines, hydroelectric turbines and wind turbines. A direct consequence of unsteady separation is the erratic movement of the separation point which causes highly dynamic and unpredictable loads on an airfoil. Current computational models underestimate the aerodynamic loads due to the inaccurate prediction of the emergence and severity of unsteady flow separation especially in response to a sudden …

Achieving Pregnancy Using Primary Care Interventions To Identify The Fertile Window, Thomas Bouchard, Richard J. Fehring, Mary Schneider

College of Nursing Faculty Research and Publications

Objective: To determine the effectiveness of achieving pregnancy with focused intercourse in the fertile window identified using natural fertility indicators. Methods: 24-cycle prospective effectiveness study. Setting: A North American web-based fertility monitoring service. Participants: 256 North American women aged 20–43 (mean age 29.2 years) seeking to achieve pregnancy. Intervention: Participants identified their fertile window with either electronic hormonal fertility monitoring or cervical mucus monitoring, or both, and recorded their observations on an online fertility tracking system. Main outcome measures: Pregnancies were validated by nurses with an online self-assessed pregnancy evaluation form. Survival analysis was used to determine pregnancy rates. Results: …

Common Birth Control Shot Linked To Risk Of Hiv Infection, Jeff Hansen

Browse All News

No abstract provided.

Study Examines Obesity And Reproductive Status Of Zoo Elephants, Staff

Browse All News

No abstract provided.

Methylation In Mycobacterium Tuberculosis Is Lineage Specific With Associated Mutations Present Globally, Jody Phelan, Paola Florez De Sessions, Leopold Tientcheu, Joao Perdigao, Diana Machado, Rumina Hasan, Zahra Hasan, Indra L. Bergval, Richard Anthony, Ruth Mcnerney

Department of Pathology and Laboratory Medicine

DNA methylation is an epigenetic modification of the genome involved in regulating crucial cellular processes, including transcription and chromosome stability. Advances in PacBio sequencing technologies can be used to robustly reveal methylation sites. The methylome of the Mycobacterium tuberculosis complex is poorly understood but may be involved in virulence, hypoxic survival and the emergence of drug resistance. In the most extensive study to date, we characterise the methylome across the 4 major lineages of M. tuberculosis and 2 lineages of M. africanum, the leading causes of tuberculosis disease in humans. We reveal lineage-specific methylated motifs and strain-specific mutations that are …

The Constitution Of Mothers: Gender Equality And Social Reproduction In The United States And The World, Julie C. Suk

ConLawNOW

In March of 2017, on the heels of the Women’s March, Nevada became the first state in 35 years to ratify the Equal Rights Amendment (ERA). If Nevada’s ratification is legally valid, then ratification by merely two additional states would be sufficient to add a sex equality guarantee to the U.S. Constitution. But the question remains: would the ERA change what the law does to gender relations and gender equality—or would a constitutional guarantee of sex equality be merely symbolic today? Even though the Equal Protection Clause is now read to prohibit sex discrimination in most instances, and statutes prohibit …

Fisheries Science Afs 215, Michael Cerbo

Library Impact Statements

No abstract provided.

Genomic Analysis Of Demographic History And Ecological Niche Modeling In The Endangered Sumatran Rhinoceros Dicerorhinus Sumatrensis, Herman L. Mays Jr., Chih-Ming Hung, Pei-Jen Shaner, James Denvir, Megan Justice, Shang-Fang Yang, Terri L. Roth, David A. Oheler, Jun Fan, Swanthana Rekulapally, Donald A. Primerano

Clinical and Translational Science Institute

The vertebrate extinction rate over the past century is approximately 22 – 100 times greater than background extinction rates [1] and large mammals are particularly at risk [2, 3]. Quaternary megafaunal extinctions have been attributed to climate change [4], overexploitation [5] or a combination of the two [6]. Rhinoceroses (Family: Rhinocerotidae) have a rich fossil history replete with iconic examples of climate-induced extinctions [7], but current pressures threaten to eliminate this group entirely. The Sumatran Rhinoceros (Dicerorhinus sumatrensis) is among the most imperiled mammals on earth. The 2011 population was estimated at ≤ 216 wild individuals [8] and currently the …

Special Relativity, 3, David Peak

Special Relativity

A few kinematic consequences of the Lorentz transformations

How big is gamma?

Stem Stories, January 2018, #2, Ginger L'Heureux

STEM Stories

First Generation Series #2

Genomic Analysis Of Demographic History And Ecological Niche Modeling In The Endangered Sumatran Rhinoceros Dicerorhinus Sumatrensis, Herman L. Mays, Chih-Ming Hung, Pei-Jen Shaner, James Denvir, Megan Justice, Shang-Fang Yang, Terri L. Roth, David A. Oehler, Jun Fan, Swanthana Rekulapally, Donald A. Primerano

Biochemistry and Microbiology

The vertebrate extinction rate over the past century is approximately 22–100 times greater than background extinction rates [1], and large mammals are particularly at risk [2, 3]. Quaternary megafaunal extinctions have been attributed to climate change [4], overexploitation [5], or a combination of the two [6]. Rhinoceroses (Family: Rhinocerotidae) have a rich fossil history replete with iconic examples of climate-induced extinctions [7], but current pressures threaten to eliminate this group entirely. The Sumatran rhinoceros(Dicerorhinus sumatrensis) is among the most imperiled mammals on earth. The 2011 …

White Matter Tauopathy: Transient Functional Loss And Novel Myelin Remodeling., Joshua Jackson, Gabby Bianco, Angelo O. Rosa, Katrina Cowan, Peter Bond, Oleg Anichtchik, Robert Fern

More Faculty of Health Research

Early white matter (WM) changes are common in dementia and may contribute to functional decline. We here examine this phenomenon in an induced dementia model for the first time. We report a novel and selective form of myelin injury as the first manifestation of tauopathy in the adult central nervous system. Myelin pathology rapidly followed the induction of a P301 tau mutation associated with fronto-temporal dementia in humans (rTG4510 line). Damage involved focal disruption of the ad-axonal myelin lamella and internal oligodendrocyte tongue process, followed by myelin remodeling with features of re-myelination that included myelin thinning and internodal shortening. The …

Feeding Immunity: Physiological And Behavioral Responses To Infection And Resource Limitation, Sarah A. Budischak, Christina B. Hansen, Quentin Caudron, Romain Garnier, Tyler R. Kartzinel, István Pelczer, Clayton E. Cressler, Anieke Van Leeuwen, Andrea L. Graham

School of Biological Sciences: Faculty Publications

Resources are a core currency of species interactions and ecology in general (e.g., think of food webs or competition). Within parasite-infected hosts, resources are divided among the competing demands of host immunity and growth as well as parasite reproduction and growth. Effects of resources on immune responses are increasingly understood at the cellular level (e.g., metabolic predictors of effector function), but there has been limited consideration of how these effects scale up to affect individual energetic regimes (e.g., allocation trade-offs), susceptibility to infection, and feeding behavior (e.g., responses to local resource quality and quantity). We experimentally rewilded laboratory mice (strain …

Presentation, College Of Arts And Sciences, Joint Council Of Academic And Student Affairs Meeting, January 8, 2018, University Of South Florida St. Petersburg. College Of Arts And Sciences

Council of Academic and Student Affairs

The PowerPoint from a presentation about the College of Arts and Sciences to the Joint Council of Academic and Student Affairs at the University of South Florida St. Petersburg.

From Outsiders To In-Betweens : Identity Negotiation Of Thai Female Migrants In Hong Kong, Yu Zhang

Lingnan Theses (MPhil & PhD)

As a multicultural cosmopolitan, transnational migration has an inseparable relationship with the socio-economic development of Hong Kong, the phenomenon of transnational marriage between Hong Kong men and Southeast Asian women has become one of the influential factors impacting the family and social structure in this city. This research aimed to investigate the complicated identities of Thai female migrants within this specific socio-demographic group in Hong Kong. This study, guided by identity, gender, and narrative perspectives, examines the subjective experiences of Thai female migrants through their journey of transnational migration to Hong Kong from an intersectionality perspective. Therefore, the central focus …