Digital Commons Network^™

Assessment Of Hydrologic Connectivity In An Ungauged Wetland With Insar Observations, Fernando Jaramillo, Ian Brown, Pascal Castellazzi, Luisa Espinosa, Alice Guittard, Sang Hoon Hong, Victor H. Rivera-Monroy, Shimon Wdowinski

Faculty Publications

The Ciénaga Grande de Santa Marta (CGSM) is one of the world's most productive tropical wetlands and one that has witnessed some of the greatest recorded dieback of mangroves. Human-driven loss of hydrologic connectivity by roads, artificial channels and water flow regulation appears to be the reason behind mangrove mortality in this ungauged wetland. In this study, we determined the CGSM's current state of hydrologic connectivity by combining a remote sensing technique, termed as Wetland Interferometric Synthetic Aperture Radar (InSAR), with a hydrologic study of river water discharge. For this research, we processed 29 ALOS-PALSAR acquisitions taken during the period …

Future Hydrological Alterations In The Mekong Delta Under The Impact Of Water Resources Development, Land Subsidence And Sea Level Rise, Thanh Duc Dang, Thomas A. Cochrane, Mauricio E. Arias, Van Pham Dang Tri

Civil and Environmental Engineering Faculty Publications

Study Region: The Mekong floodplains and delta are among the most agriculturally productive and biologically diverse waterscapes of the world, but sea level rise, land subsidence, and the proposed upstream development of over 126 hydropower dams and extensive delta-based water infrastructure have raised concern due to potential impacts on the hydrology of the region.

Study Focus: This study aims to quantify the effects of water infrastructure development, land subsidence and sea level rise on hydrological regimes of the Mekong floodplains and delta through the development and application of a hydrodynamic model.

New Hydrological Insights for the Region: Depending on hydrological …

Gender Issues In News Coverage, Margaretha Geertsema-Sligh

Scholarship and Professional Work - Communication

This entry discusses the participation and representation of women in the news media. Women entered journalism primarily to appeal to female audiences in the 19^th century and were expected to write about topics considered to be of interest for women, such as food, fashion, family and furniture. Today, global studies show that women remain underrepresented at all levels of news organizations, with a glass ceiling preventing women from rising to top positions. Female journalists are especially facing challenges in war reporting and sports reporting, and as opinion columnists. In terms of representation, women are frequently represented in a negative …

Self-Reported Academic Performance In Relation To Health Behaviours Among Bahria University Students, Rehana Rehman, Amara Zafar, Aleena Mohib, Mehwish Hussain, Rabiya Ali

Department of Biological & Biomedical Sciences

Objective: To find an association between self-reported academic performance with different socio-demographic factors, health behaviours and mental health amongst university students.
Methods: This cross-sectional study was conducted at Bahria University, Karachi, from January 2012 to December 2013, and comprised university students of different disciplines. An anonymous, self-reported questionnaire was distributed among the subjects. Convenient sampling technique was used. Demographic information, including age, gender and field of study, were obtained. Depresion was evaluated via Centre for Epidemiological Studies Depression Scale. SPSS 22 was used to analyse data.
Results: Of the 813 respondents, 334(41.1%) were males and 479(58.9%) females. The mean age …

Chronicles Of Hypoxia: Time-Series Buoy Observations Reveal Annually Recurring Seasonal Basin-Wide Hypoxia In Muskegon Lake – A Great Lakes Estuary, Bopaiah Biddanda, Anthony D. Weinke, Scott T. Kendall, Leon C. Gereaux, Thomas M. Holcomb, Michael J. Snider, Deborah K. Dila, Stephen A. Long, Chris Vandenberg, Katie Knapp, Dirk J. Koopmans, Kurt Thompson, Janet H. Vail, Mary E. Ogdahl, Qianqian Liu, Thomas H. Johengen, Eric J. Anderson, Steven A. Ruberg

Open Access Publishing Support Funded Articles

We chronicled the seasonally recurring hypolimnetic hypoxia in Muskegon Lake – a Great Lakes estuary over 3 years, and examined its causes and consequences. Muskegon Lake is a mesotrophic drowned river mouth that drains Michigan's 2nd largest watershed into Lake Michigan. A buoy observatory tracked ecosystem changes in the Muskegon Lake Area of Concern (AOC), gathering vital time-series data on the lake's water quality from early summer through late fall from 2011 to 2013 (www.gvsu.edu/buoy). Observatory-based measurements of dissolved oxygen (DO) tracked the gradual development, intensification and breakdown of hypoxia (mild hypoxia b4 mg DO/L, and severe hypoxia b2 mg …

Moral Mode Switching: From Punishment To Public Health, Stephen Koppel

Dissertations, Theses, and Capstone Projects

A public health response to drug offenses has potential to improve both public safety and public health. However, the public’s desire for retribution represents a possible hindrance to reform. Relying on dual-process theory of moral decision-making, this dissertation examines agreement among laypeople about the relative blame deserved for various crime types, and probes several possible predictors of support—the need for cognition (“NFC”), intergroup bias, and free-will doubt—for retributive as well as consequentialist responses to crime. Findings from several web-based experiments show: (a) in comparison to core crimes (eg., murder) substantially less agreement about the relative blame deserved for noncore crimes …

Barriers And Facilitators To Antiretroviral Therapy Adherence Among Peruvian Adolescents Living With Hiv: A Qualitative Study, Jerome Galea, Milagros Wong, Maribel Muñoz, Emiliano Valle, Segundo R. Leon, Dayana D. Perez, Lenka Kolevic, Molly F. Franke

Social Work Faculty Publications

AIDS deaths among adolescents are increasing globally. This qualitative study investigated the barriers and facilitators to cART adherence among Peruvian adolescents living with HIV. Guided by a social ecological model, we analyzed transcripts from 24 psychosocial support groups for HIV-positive adolescents aged 13–17 years and 15 individual, in-depth interviews with cART providers and caregivers to identify the barriers and facilitators to cART adherence at the individual, family/caregiver and hospital levels. Most barriers and facilitators to cART adherence clustered at the individual and family/caregiver levels, centering on support provided to adolescents; history of declining health due to suboptimal cART adherence; side …

A Global Perspective On The Trophic Geography Of Sharks, Christopher S. Bird, Ana Verissimo, Sarah Magozzi, Katya G. Abrantes, Alex Aguilar, Hassan Al-Reasi, Adam Barnett, Dana M. Bethea, Gerard Biais, Asuncion Borrell, Marc Bouchoucha, Mariah Boyle, Edward J. Brooks, Juerg Brunnschweiler, Paco Bustamante, Aaron Carlisle, Diana Catarino, Stephane Caut, Yves Cherel, Tiphaine Chouvelon, Diana Churchill, Javier Ciancio, Julien Claes, Ana Colaço, Dean L. Courtney, Pierre Cresson, Ryan Daly, Leigh De Necker, Tetsuya Endo, Ivon Figueiredo, Ashley J. Frisch, Joan Holst Hansen, Michael Heithaus, Nigel E. Hussey, Johannes Iitembu, Francis Jaunes, Michael J. Kinney, Jeremy J. Kiszka, Sebastian A. Klarian, Dorothee Kopp, Robert Leaf, Yunkai Li, Anne Lorrain, Daniel J. Madigan, Aleksandra Maljkovic, Luis Malpica-Cruz, Philip Matich, Mark G. Meekan, Frederic Menard, Gui M. Menezes, Samantha E. M. Munroe, Michael C. Newman, Yannis P. Papastamatiou, Heidi Pethybridge, Jeffrey D. Plumlee, Carlos Polo-Silva, Katie Quaeck-Davis, Vincent Raoult, Jonathan Reum, Yassir Eden Torres-Rojas, David S. Shiffman, Oliver N. Shipley, Conrad W. Speed, Michelle D. Staudinger, Amy K. Teffer, Alexander Tilley, Maria Valls, Jeremy Vaudo, Tak-Cheung Wai, R. J. David Wells, Alex S. J. Wyatt, Andrew Yool, Clive N. Trueman

Marine & Environmental Sciences Faculty Articles

Sharks are a diverse group of mobile predators that forage across varied spatial scales and have the potential to influence food web dynamics. The ecological consequences of recent declines in shark biomass may extend across broader geographic ranges if shark taxa display common behavioural traits. By tracking the original site of photosynthetic fixation of carbon atoms that were ultimately assimilated into muscle tissues of 5,394 sharks from 114 species, we identify globally consistent biogeographic traits in trophic interactions between sharks found in different habitats. We show that populations of shelf-dwelling sharks derive a substantial proportion of their carbon from regional …

Tremblings, February 2018, Western Aspen Alliance

Tremblings

Ten Years of Aspen Science Outreach

Paul C. Rogers

Like any 10-year-old, we still have a lot of growing up to do. We’re full of energy, regularly enduring bruises and bumps. What parent doesn’t look at their child after a decade and see great potential with a dash of trepidation? Still, 10 years is a significant landmark even after the candles are blown out. Let’s take a brief look at where the Western Aspen Alliance (WAA) has been and where we’re heading.

Effects Of Elevated Co2, Increased Nitrogen Deposition, And Plant Diversity On Aboveground Litter And Root Decomposition, Xiaoan Zuo, Johannes Knops

School of Biological Sciences: Faculty Publications

Global change-induced litter decomposition strongly affects the carbon (C) and nitrogen (N) dynamics in grassland ecosystems. However, few studies show the interactive effects of global change factors on litter and root decomposition. We conducted a four-year grassland field experiment to examine the quality and decomposition of litter and root in a three-factorial experiment with elevated CO₂, increased N deposition, and plant species richness. We found that elevated CO₂ decreased the litter N content and root lignin content. N addition increased the root N content and decreased the litter lignin content. Increasing plant richness decreased the N and …

New Approaches To Model Simulated Spatio-Temporal Moran's Index, Nhan Bu, Jennifer Lorio, Norou Diawara, Kumar Das, Lance Waller

Mathematics & Statistics Faculty Publications

The Moran's index is a statistic that measures spatial autocorrelation; it quantifies the degree of dispersion (or clustering) of objects in space. However, when investigating data over a general area, a single global Moran statistic may not give a sufficient summary of the spread, behavior, features or latent surfaces shared by neighboring areas; rather, by partitioning the area and taking the Moran statistic of each divided subareas, we can discover patterns of the local neighbors not otherwise apparent. In this paper, we present a simulation experiment where the local Moran values are computed and a time variable is added to …

Auditing Snomed Ct Hierarchical Relations Based On Lexical Features Of Concepts In Non-Lattice Subgraphs, Licong Cui, Olivier Bodenreider, Jay Shi, Guo-Qiang Zhang

Computer Science Faculty Publications

Objective—We introduce a structural-lexical approach for auditing SNOMED CT using a combination of non-lattice subgraphs of the underlying hierarchical relations and enriched lexical attributes of fully specified concept names. Our goal is to develop a scalable and effective approach that automatically identifies missing hierarchical IS-A relations.

Methods—Our approach involves 3 stages. In stage 1, all non-lattice subgraphs of SNOMED CT’s IS-A hierarchical relations are extracted. In stage 2, lexical attributes of fully-specified concept names in such non-lattice subgraphs are extracted. For each concept in a non-lattice subgraph, we enrich its set of attributes with attributes from its ancestor …

Agrochemicals Increase Risk Of Human Schistosomiasis By Supporting Higher Densities Of Intermediate Hosts, Neal T. Halstead, Christopher M. Hoover, Arathi Arakala, David J. Civitello, Guilio A. De Leo, Manoj Gambhir, Steve A. Johnson, Nicolas Jouanard, Kristin A. Loerns, Karena Nguyen, Jason R. Rohr

Integrative Biology Faculty and Staff Publications

Schistosomiasis is a snail-borne parasitic disease that ranks among the most important water-based diseases of humans in developing countries. Increased prevalence and spread of human schistosomiasis to non-endemic areas has been consistently linked with water resource management related to agricultural expansion. However, the role of agrochemical pollution in human schistosome transmission remains unexplored, despite strong evidence of agrochemicals increasing snail-borne diseases of wildlife and a projected 2- to 5-fold increase in global agrochemical use by 2050. Using a field mesocosm experiment, we show that environmentally relevant concentrations of fertilizer, a herbicide, and an insecticide, individually and as mixtures, increase densities …

Total Sleep Time And Kynurenine Metabolism Associated With Mood Symptom Severity In Bipolar Disorder, Dahlia Mukherjee, Venkatesh B. Krishnamurthy, Caitlin E. Millett, Aubrey Reider, Adem Can, Maureen Groer, Dietmar Fuchs, Teodore T. Postolache, Erika F. H. Saunders

Nursing Faculty Publications

Objective: Chronic, low‐level inflammation is associated with symptomatic bipolar disorder (BD) and with chronic insomnia. Disrupted sleep is a feature of episodes of both mania and depression. We examined the effect of neopterin, a marker of cellular immune activation, and kynurenine (KYN), an inflammatory byproduct of the serotonin pathway, on the association between total sleep time and depression severity in BD.

Method: Twenty‐one symptomatic BD participants and 28 healthy controls (HC) were recruited and followed during usual clinical care. At baseline and after symptomatic recovery, total sleep time was objectively measured with actigraphy for 1 week and blood plasma was …

Lack Of Association Of Statin Use With Vitamin D Levels In A Hospital Based Population Of Type 2 Diabetes Mellitus Patients, Khalida Iqbal, Najmul Islam, Iqbal Azam Syed, Naseema Mehboobali, Mohammad Perwaiz Iqbal

Department of Biological & Biomedical Sciences

Objective: To investigate the relationship of statins (drug given to reduce serum levels of LDL-cholesterol) on vitamin D levels of Pakistani type 2 diabetes mellitus (DM) patients in a hospital in Karachi.
Methods: In a cross-sectional survey, 312 consecutive patients with type 2 DM (219 males and 93 females, age 22-70 years) were recruited with informed consent. A questionnaire was administered to find out whether they were statin users or non-users. Serum was analyzed for concentrations of 25(OH) vitamin D [25(OH)D] and other related biomarkers such as serum cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, phosphate and calcium using kit methods. Multiple Linear …

Simian Virus 40 Large T Antigen As A Model To Test The Efficacy Of Flouroquinolones Against Viral Helicases, Sammer Siddiqui, Muhammad F. Anwar, Sadaf Naeem, Syed Hani Abidi, Shamshad Zarina, Syed Ali

Department of Biological & Biomedical Sciences

Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during replication. The LT-Ag has been employed in the studies of helicase structure and function, and has served as a model helicase for the screening of antiviral drugs that target viral helicase. In this study, using in vitro enzyme assays and in silico computer modeling, we screened a batch of 18 fluoroquinolones to assess their potential as antivirals by virtue of their inhibition of the LT-Ag helicase. …

Concussion, Microvascular Injury, And Early Tauopathy In Young Athletes After Impact Head Injury And An Impact Concussion Mouse Model., Chad A Tagge, Andrew M Fisher, Olga V Minaeva, Amanda Gaudreau-Balderrama, Juliet A Moncaster, Xiao-Lei Zhang, Mark W Wojnarowicz, Noel Casey, Haiyan Lu, Olga N Kokiko-Cochran, Sudad Saman, Maria Ericsson, Kristen D. Onos, Ronel Veksler, Vladimir V Senatorov, Asami Kondo, Xiao Z Zhou, Omid Miry, Linnea R Vose, Katisha R Gopaul, Chirag Upreti, Christopher J Nowinski, Robert C Cantu, Victor E Alvarez, Audrey M Hildebrandt, Erich S Franz, Janusz Konrad, James A Hamilton, Ning Hua, Yorghos Tripodis, Andrew T Anderson, Gareth R Howell, Daniela Kaufer, Garth F Hall, Kun P Lu, Richard M Ransohoff, Robin O Cleveland, Neil W Kowall, Thor D Stein, Bruce T Lamb, Bertrand R Huber, William C Moss, Alon Friedman, Patric K Stanton, Ann C Mckee, Lee E Goldstein

Faculty Research 2018

The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood. We examined post-mortem brains from teenage athletes in the acute-subacute period after mild closed-head impact injury and found astrocytosis, myelinated axonopathy, microvascular injury, perivascular neuroinflammation, and phosphorylated tau protein pathology. To investigate causal mechanisms, we developed a mouse model of lateral closed-head impact injury that uses momentum transfer to induce traumatic head acceleration. Unanaesthetized mice subjected to unilateral impact exhibited abrupt onset, transient course, and rapid resolution of a concussion-like syndrome characterized by altered arousal, contralateral hemiparesis, truncal ataxia, locomotor …

Genome-Wide Interactions With Dairy Intake For Body Mass Index In Adults Of European Descent, Caren E. Smith, Jack L. Follis, Hassan S. Dashti, Toshiko Tanaka, Mariaelisa Graff, Amanda M. Fretts, Tuomas O. Kilpeläinen, Mary K. Wojczynski, Kris Richardson, Mike A. Nalls, Christina-Alexandra Schulz, Yongmei Liu, Alexis C. Frazier-Wood, Esther Van Eekelen, Carol Wang, Paul S. De Vries, Vera Mikkilä, Rebecca Rohde, Bruce M. Psaty, Torben Hansen, Mary F. Feitosa, Chao-Qiang Lai, Denise K. Houston, Luigi Ferruci, Ulrika Ericson, Zhe Wang, Renée De Mutsert, Wendy H. Oddy, Ester A. L. De Jonge, Ilkka Seppälä, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Scope: Body weight responds variably to the intake of dairy foods. Genetic variation may contribute to inter‐individual variability in associations between body weight and dairy consumption.

Methods and results: A genome‐wide interaction study to discover genetic variants that account for variation in BMI in the context of low‐fat, high‐fat and total dairy intake in cross‐sectional analysis was conducted. Data from nine discovery studies (up to 25 513 European descent individuals) were meta‐analyzed. Twenty‐six genetic variants reached the selected significance threshold (p‐interaction <10⁻⁷⁾, and six independent variants (LINC01512‐rs7751666, PALM2/AKAP2‐rs914359, ACTA2‐rs1388, PPP1R12A‐rs7961195, LINC00333‐rs9635058, …

Complete Genome Sequences Of 44 Arthrobacter Phages, Karen K. Klyczek, Deborah Jacobs-Sera, Tamarah L. Adair, Sandra D. Adams, Sarah L. Ball, Robert C. Benjamin, J. Alfred Bonilla, Caroline A. Breitenberger, Charles J. Daniels, Bobby L. Gaffney, Melinda Harrison, Lee E. Hughes, Rodney A. King, Gregory P. Krukonis, A. Javier Lopez, Kirsten Monsen-Collar, Marie C. Pizzorno, Claire A. Rinehart, Amanda K. Staples, Emily L. Stowe, Rebecca A. Garlena, Daniel A. Russell, Steven G. Cresawn, Welkin H. Pope, Graham F. Hatfull

Department of Biology Faculty Scholarship and Creative Works

We report here the complete genome sequences of 44 phages infecting Arthrobacter sp. strain ATCC 21022. These phages have double-stranded DNA genomes with sizes ranging from 15,680 to 70,707 bp and G+C contents from 45.1% to 68.5%. All three tail types (belonging to the families Siphoviridae, Myoviridae, and Podoviridae) are represented.

Aging Is Associated With A Prefrontal Lateral-Medial Shift During Picture-Induced Negative Affect, C. M. Van Reekum, S. M. Schaefer, R. C. Lapate, Catherine Norris, P. A. Tun, M. E. Lachman, C. A. Ryff, R. J. Davidson

Psychology Faculty Works

The capacity to adaptively respond to negative emotion is in part dependent upon lateral areas of the prefrontal cortex (PFC). Lateral PFC areas are particularly susceptible to age-related atrophy, which affects executive function (EF). We used structural and functional magnetic resonance imaging (MRI) to test the hypothesis that older age is associated with greater medial PFC engagement during processing of negative information, and that this engagement is dependent upon the integrity of grey matter structure in lateral PFC as well as EF. Participants (n = 64, 38–79 years) viewed negative and neutral scenes while in the scanner, and completed cognitive …

Sleep Disturbance In Men Receiving Androgen Deprivation Therapy For Prostate Cancer: The Role Of Hot Flashes And Nocturia, Brian D. Gonzalez, Brent J. Small, Mallory G. Cases, Noelle L. Williams, Mayer N. Fishman, Paul B. Jacobsen, Heather S. L. Jim

Aging Studies Faculty Publications

Background: Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and controls and examined whether sleep disturbance in ADT recipients is attributable to the influence of ADT on hot flashes and nocturia.

Methods: Patients with prostate cancer were assessed before or within 1 month after the initiation of ADT as well as 6 months and 12 months later (78 patients). Patients with prostate cancer were …

Assessment Of Maternal And Infant Outcomes Of Moderately Malnourished Pregnant Adolescents In Malawi, Alyssa Marie Friebert

Master's Theses

Background: Adolescent childbearing and maternal malnutrition are common in low- and middle-income countries and are associated with increased risk for poor maternal and infant outcomes. Adolescent pregnancy compounded with moderate malnutrition exacerbates outcomes common to both individually. Supplementary foods may be a way to improve outcomes in malnourished adolescent pregnant women.

Objective: To retrospectively assess maternal and infant outcomes in moderately malnourished pregnant young adolescents (16-17 YO), older adolescents (18-19 YO), and adults (≥20 YO) in response to one of three nutritional interventions and in a pooled treatment group analysis, and to assess differences in infant outcomes by infant gender. …

A Subwavelength Perfect Absorbing Metamaterial Patch Array Coupled With A Molecular Resonance, Michael F. Finch, Brian A. Lail

Electrical Engineering and Computer Science Faculty Publications

A perfectly absorbing metamaterial (PAMM) coupled with vibrational modes has varied applications ranging from surface-enhanced vibrational spectroscopy to biological sensing. This endeavor considers a subwavelength PAMM sensor design and analysis using a commercially available finite element method (FEM) solver and analytically with temporal coupled mode theory (TCMT). A carbon double oxygen bond (C=O) at 52 THz or 1733 cm⁻¹ that resides in poly(methyl methacrylate), PMMA, will be used as a stand-in analyte. Normal mode splitting that results from the resonant coupling between the PAMM and analyte’s molecular resonance is investigated and analyzed.

Cime Newsletter : February 2018, Cime

Centre for Innovation in Medical Education (CIME) Archives

- Spie Facilitated Research Workshops

- Introductory Clinical Simulation Workshop for Nursing Education Services (NES)

- Laerdal Training in High Fidelity Simulators

- Ms. Hamida Babool, TKN Volunteer, Sharing her Experience of CIME

- AKU’s 3rd Orthopaedic Review Course

- English Language Fair 2018

Curriculum Subcommittee Agenda, February 1, 2018, Utah State University

Educational Policies Committee

Program Proposal

• Offering a Bachelor of Science in Nutrition Science
• Offering a Bachelor of Science in Dietetics
• Offering a Bachelor of Science in Food Science
• Establishing a Department of Marketing and Strategy
• Offering a Master of Science in Data Science

Semester Course Approval Reviews

Other

• Removing Semesters Traditionally Taught from Catalog Descriptions
• Zero Credit Classes
• R401 Process Flow Chart
• Syllabus Update
• Curriculog Input

Hawks' Herald -- Feb. 1, 2018, Roger Williams University

Hawk's Herald

No abstract provided.

Academics: The Newsletter Of The Swosu College Of Arts And Sciences, Peter Grant

aCAdemicS: The Newsletter of the SWOSU College of Arts & Sciences

No abstract provided.

Analyzing The Genes Related To Nicotine Addiction Or Schizophrenia Via A Pathway And Network Based Approach, Ying Hu, Zhonghai Fang, Yichen Yang, Dekai Rohlsen-Neal, Feng Cheng, Ju Wang

Pharmacy Faculty Publications

The prevalence of tobacco use in people with schizophrenia is much higher than in general population, which indicates a close relationship between nicotine addiction and schizophrenia. However, the molecular mechanism underlying the high comorbidity of tobacco smoking and schizophrenia remains largely unclear. In this study, we conducted a pathway and network analysis on the genes potentially associated with nicotine addiction or schizophrenia to reveal the functional feature of these genes and their interactions. Of the 276 genes associated with nicotine addiction and 331 genes associated with schizophrenia, 52 genes were shared. From these genes, 12 significantly enriched pathways associated with …

Preliminary Evidence That Digit Length Ratio (2d:4d) Predicts Neural Response To Delivery Of Motivational Stimuli, Troy A. Webber, Heather E. Soder, Geoffrey Potts, Marina A Bornovalova

Psychology Faculty Publications

Reduced relative length of the 2nd to 4th digits (2D:4D) is thought to partially reflect fetal testosterone (FT) exposure, a process suspected to promote relatively permanent effects on the brain and behavior via structural and functional neuroadaptations. We examined the effect of 2D:4D on neural response − assessed by P2a and feedback-related negativity (FRN) event-related potentials (ERPs) − to motivational stimuli (reward or punishment) using two counterbalanced conditions of a passive S1/S2 outcome prediction design. P2a to expected and unexpected delivered rewards or punishments ($1 or white noise burst, respectively) and FRN to withheld rewards or punishments ($0 or silence, …

Genetic And Environmental Influences On The Codevelopment Among Borderline Personality Disorder Traits, Major Depression Symptoms, And Substance Use Disorder Symptoms From Adolescence To Young Adulthood, Marina A. Bornovalova, Brad Verhulst, Troy Alan Webber, Matt Mcgue, William G. Iacono, Brian M. Hicks

Psychology Faculty Publications

Although borderline personality disorder (BPD) traits decline from adolescence to adulthood, comorbid psychopathology such as symptoms of major depressive disorder (MDD), alcohol use disorder (AUD), and drug use disorders (DUDs) likely disrupt this normative decline. Using a longitudinal sample of female twins (N = 1,763), we examined if levels of BPD traits were correlated with changes in MDD, AUD, and DUD symptoms from ages 14 to 24. A parallel process biometric latent growth model examined the contributions of genetic and environmental factors to the relationships between developmental components of these phenotypes. Higher BPD trait levels predicted a greater rate of …