Digital Commons Network^™

Using Dna For Data Storage: Encoding And Decoding Algorithm Development, Kelsey Suyehira

Boise State University Theses and Dissertations

The recent explosion of digital data has created an increasing need for improved data storage architectures with the ability to store large amounts of data over extensive periods of time. DNA as a data storage solution shows promise with a thousand times greater increase in information density and information retention times ranging from hundreds to thousands of years. This thesis explores the challenges and potential approaches in developing an encoding and decoding algorithm for use in a DNA data storage architecture. When encoding binary data into sequences representing DNA strands, the algorithms should account for biological constraints representing the idiosyncrasies …

Stable Isotope Geochemistry Of Bioapatite, Amanda E. Drewicz

Boise State University Theses and Dissertations

The Cenozoic Era was a time period where dynamic shifts in climate created for both warm-wet greenhouse environments of the mid-Miocene Climatic Optimum (MMCO), and cool-dry, glacial periods of the late Pleistocene. The Cenozoic is close to our own time period, and although past climate reconstructions cannot be used as direct analogs for future climate change, understanding previous environmental responses can help inform policy surrounding future climate change. Presented here are climate reconstructions of the interior western United States, from two different geologic time periods. Each had a different climate, that differed greatly from modern day environments. The use of …

Post-Fire Variation In Aeolian Deposition In The Northern Great Basin, Clayton Roehner

Boise State University Theses and Dissertations

Aeolian processes play a significant role in the redistribution of sediment and nutrients in sparsely vegetated sagebrush-steppe ecosystems. When fire is introduced to the landscape, decreased surface roughness and associated threshold friction velocities allow for the increased mobility of surface sediments and burnt organic material, mobilizing previously stable material. Once material is entrained, interactions between a dynamic atmosphere and complex topography control the spatial distribution of aeolian deposition over a landscape. Given the significant impact of fire on aeolian processes in semi-arid deserts, we posit that postfire aeolian redistribution of material is an important control on the spatial variability of …

Structure-Based Drug Design Of Novel Therapeutics Targeting Oncostatin M, Kelsey Skluzacek

Boise State University Theses and Dissertations

At 30% of all new diagnoses, the most prevalent malignancy for women is breast cancer, which in the United States will result in an estimated 266,000 new cases this year alone. Of the patients diagnosed with breast cancer, approximately 10-15% will develop distant metastases within three years of the initial detection of a primary tumor. For comparison, the five-year survival rate for localized breast cancer is 99%, whereas, the survival rate for metastatic breast cancer drops drastically to only 27%. The significant difference in survival rates is indicative of a need for a novel treatment strategy for metastatic breast cancer. …

Harnessing The Physical Properties Of Zno Nanoparticles For Biological Applications And Factors That Impact Zno Nanoparticle Toxicity, Joshua Eixenberger

Boise State University Theses and Dissertations

The production of materials at the nanoscale leads to novel properties and has made the field of nanotechnology a part of everyday life. Numerous applications of nanomaterials have led to their use in electronics, optics, and medicine. However, creating materials at such a small size brings them on the same scale as many biomolecules and cellular components, altering their interactions with biological systems. This can lead to unintended biological impacts as many nanomaterials are considerably more toxic than their bulk counterpart material. ZnO nanoparticles (nZnO) are particularly interesting in this context. The FDA classifies ZnO as a generally recognized as …

Resilience As A Mediating Factor For Behavioral And Academic Outcomes For Adolescents With Executive Functioning Impairments, Bronwyn Louise Lehman

Dissertations

Executive functioning (EF) and resilience have become topics of interest in psychology and education as being key components in determining a person’s ability to engage meaningfully and effectively within their environment as well as a reason for better than expected outcomes. The purpose of this study was to examine whether self-reported resilience factors could account for certain behavioral, adaptive, and academic outcomes for adolescents in the presence of executive functioning difficulties. Mediation analysis was utilized to determine resilience (measured using the Journey to Wellness scale) as a mediating factor for academic and behavioral outcomes (measured using select subscales on the …

Applications Of Node-Based Resilience Graph Theoretic Framework To Clustering Autism Spectrum Disorders Phenotypes, John Matta, Junya Zhao, Gunes Ercal, Tayo Obafemi-Ajayi

Electrical and Computer Engineering Faculty Research & Creative Works

With the growing ubiquity of data in network form, clustering in the context of a network, represented as a graph, has become increasingly important. Clustering is a very useful data exploratory machine learning tool that allows us to make better sense of heterogeneous data by grouping data with similar attributes based on some criteria. This paper investigates the application of a novel graph theoretic clustering method, Node-Based Resilience clustering (NBR-Clust), to address the heterogeneity of Autism Spectrum Disorder (ASD) and identify meaningful subgroups. The hypothesis is that analysis of these subgroups would reveal relevant biomarkers that would provide a better …

Standardization Roadmap For Unmanned Aircraft Systems, Version 1.0, Kristine Kiernan, Christian Janke, Kenneth Witcher

Publications

This Standardization Roadmap for Unmanned Aircraft Systems, Version 1.0 (“roadmap”) represents the culmination of the UASSC’s work to identify existing standards and standards in development, assess gaps, and make recommendations for priority areas where there is a perceived need for additional standardization and/or pre-standardization R&D.

The roadmap has examined 64 issue areas, identified a total of 60 gaps and corresponding recommendations across the topical areas of airworthiness; flight operations (both general concerns and application-specific ones including critical infrastructure inspections, commercial services, and public safety operations); and personnel training, qualifications, and certification. Of that total, 40 gaps/recommendations have been identified as …

Nonlinear Sliding Mode Observer Applied To Microalgae Growth, Rebecca J. Griffith

Doctoral Dissertations and Master's Theses

Modeling biological processes, such as algae growth, is an area of ongoing research. The ability to understand the multitude of parameters that influence this system provides a platform for better understanding the dynamics of microalgae growth. Empirical modeling efforts look to understand sources of driving nutrients that influence harmful algal blooms (HABs). These harmful algal blooms are dense aggregates that have an increasingly negative impact on local economics, marine and freshwater systems, and public health. They result from a high influx of nitrogen and nutrients that drive the algae biomass to exponentially grow. This growth blocks out the sun, potentially …

Design And Implementation Of Intelligent Guidance Algorithms For Uav Mission Protection, Karina Rivera

Doctoral Dissertations and Master's Theses

In recent years, the interest of investigating intelligent systems for Unmanned Aerial Vehicles (UAVs) have increased in popularity due to their large range of capabilities such as on-line obstacle avoidance, autonomy, search and rescue, fast prototyping and integration in the National Air Space (NAS). Many research efforts currently focus on system robustness against uncertainties but do not consider the probability of readjusting tasks based on the remaining resources to successfully complete the mission. In this thesis, an intelligent algorithm approach is proposed along with decision-making capabilities to enhance UAVs post-failure performance. This intelligent algorithm integrates a set of path planning …

The Goldilocks Approach: A Review Of Employing Design Of Experiments In Prokaryotic Recombinant Protein Production, Barry Ryan, Albert Uhoraningoga, Gemma K. Kinsella, Gary T. .. Henehan

Articles

The production of high yields of soluble recombinant protein is one of the main objectives of protein biotechnology. Several factors, such as expression system, vector, host, media composition and induction conditions can influence recombinant protein yield. Identifying the most important factors for optimum protein expression may involve significant investment of time and considerable cost. To address this problem statistical models, such as Design of Experiments (DoE), have been used to optimise recombinant protein production. This review explores the application of DoE in the production of recombinant proteins, focusing on prokaryotic expression systems with a specific emphasis on media composition and …

Evaluation Of A Natural Challenge Model Of Zebrafish With Influenza A Virus, Kelvin Blade

Honors Theses

Influenza A virus (IAV) presents as a global public health concern, resulting in an extensive burden on morbidity and mortality rates in humans. IAV has high mutation rates, influencing emergence of new virus strains, which could lead to increased antiviral resistivity and altered virulence. Although prevention and treatment of influenza infections have been improved, animal models still play a major role in understanding of host responses and the pathogenesis of IAV infection. Zebrafish are useful host models for evaluating infectious diseases processes, especially with the ability to manipulate the genome of zebrafish. Research by others have shown that parenteral applied …

The Effect Of Spill Contaminants On Marine Biofilms And Microbially-Induced Corrosion Of Carbon Steel, Rachel Mugge

Master's Theses

There are over 2,000 known historic shipwrecks located in the northern Gulf of Mexico which are ecological and cultural resources that support the diversity of life found in the deep-sea when they become artificial reefs. Spilled crude oil and chemical dispersant from the Deepwater Horizon (DWH) spill may have impacted the preservation of deep-sea historic shipwrecks and their microbiomes if they are located in areas where oil and dispersant were deposited on the seafloor. Oil potentially accelerates corrosion of metal through a biologically-mediated process called microbially-induced corrosion (MIC). Introduction of spill contaminants may accelerate MIC on shipwreck hulls, which may …

A Novel Ultrasound Imaging Technique Using Random Signals, Anahita Khalilzadeh

Electrical Engineering Theses and Dissertations

Ultrasound imaging has been used extensively because of its benign nature and relatively low cost implementation. The most common approach for forming an image is Brightness Mode (B-Mode), which uses an array with dynamic focusing. Focus is performed through Phase Shifters that are bulky and complicated components which increases the device cost.

This research describes a new method to form an Ultrasound image, without relying on phase shifting. The proposed method offers a lower cost solution compared to the B-Mode systems and overcomes some of their inherent limitations.

The Characterization Of Leather Wwii Artifacts Using Gc/Ms And Raman Spectroscopy, Brice Houser

Fall 2018 - Chemical Analysis Class Projects

Many museums face the challenge of protecting artifacts from deterioration. This process is often hampered by the history of the artifact, which can introduce factors that start or speed up the process of deterioration. An example of this is the method used during WW II to preserve leather. Mink oil or other fatty substances are used to help preserve and soften leather. A major component of mink oil is palmitic acid.

1 This fatty acid may have reacted with the brass in the same way that the oils from the hand react with coins to make that distinctive metallic smell, …

Quantification Of Trigonellinefrom Coffee Beans And Its Correlation With The Ph, Kashif A. Shaikh, Jaspreet K. Rishi, Joshua Sebree

Fall 2018 - Chemical Analysis Class Projects

This project analyzed the amount of trigonelline preseent in coffee beans at various stages of the roasting process.

Removal Of Carbamazepine From Drinking Water, Thomas Krumpolc, Juan Rodriguez, Jordan Alex Gadberry, Zach Wiese, Paola Marrero-Rivera, Adam Johnson

Chemical Engineering Undergraduate Honors Theses

Due to the increasing prevalence of prescription medication over the past few decades, pharmaceuticals have accumulated in various water sources. This has become a public health concern because many pharmaceuticals have limited research on the effects of chronic low-level exposure. According to the World’s Health Organization (WHO), traces of pharmaceuticals products have been reported in different water sources such as surface waters, wastewater, groundwater, and drinking water.^[1] One pharmaceutical of interest that has been detected in water sources is carbamazepine. Carbamazepine (CBZ) is a common pharmaceutical prescribed for the treatment of seizure disorders, neuropathic pain, and various psychological disorders. …

Safety, Stephen M. Vantassel, Brenda K. Osthus

Wildlife Damage Management Technical Series

Wildlife damage management (WDM) is an exciting field with many opportunities to provide solutions to the complex issues involved in human-wildlife interactions. In addition, WDM wildlife control operators (WCO) face a variety of threats to their physical well-being. Injuries can result from misused (Figure 1), faulty, or poorly maintained equipment, inexperience, mishandled wildlife, harsh weather, and dangerous situations, such as electrical lines. The goals of this publication are to: * Develop an awareness of safety issues and adopt a mindset of “Safety First”, * Review the major safety threats that WCOs face, * Provide basic information for WCOs to protect …

Optimization Of The Practice Of Slow Cooling Steel Bars: A Redesign And Modernization Of Materials, Eryn Johnston

Mechanical Engineering Undergraduate Honors Theses

Throughout the process of steel making, certain grades of steel are a higher risk for defects caused by the inability to quickly diffuse hydrogen through the steel when cooled to room temperature at a normal rate based on the ambient air temperature. To reduce the hydrogen flaking defects that are caused due to hydrogen entrapment in the steel, the process of slow cooling is utilized. This process reduces the cooling rate of steel bars by keeping them at a higher temperature for extended periods and in turn gives the hydrogen a chance to fully dissipate from the steel. In many …

Influence Of Natural And Anthropogenic Environmental Variability On Larval Fish Diet, Growth, And Condition In The Northcentral Gulf Of Mexico, Angie Hoover

Master's Theses

The northern Gulf of Mexico experiences high levels of freshwater runoff annually from various sources including the Mississippi River and Mobile Bay, among other sources. Early life history stages of fishes are especially vulnerable to environmental variability created by freshwater discharge. The objectives of this study were to describe the available prey field, diet, growth and condition of larval fishes with respect to various effects of freshwater discharge in the northern Gulf. The first chapter compared these parameters in larval Gulf Menhaden (Brevoortia patronus) collected from three different water masses characterized by physical and biological parameters after the …

Antioxidant Genes In Apis Mellifera, Their Implication In Pesticide Detoxification, Nicholas Rinderer

Master's Theses

The effect of pesticides on Apis mellifera mortality as well as their effect on the transcriptional regulation of antioxidant genes was the aim of this study. Unlike previous studies, the work here shows the combined effects of pesticides imidacloprid and coumaphos on worker bees at levels likely encountered by workers using both toxological and molecular analysis. Bee brood were collected from hives and incubated until hatching. The 1 day old bees were then segregated and subjected to varying concentrations of coumaphos and imidacloprid both independently and in concert. Workers from each treatment group were removed and stored in RNA-later until …

Epic Adolescence: Contemporary Adolescence In Philip Pullman’S His Dark Materials, Chloe Felterman

Master's Theses

To find the truth of a societal construct or phenomena, it can help to look at the world of fiction and fantasy. Though this idea may seem ironic or counter-intuitive, one will find that fictional literature can reveal the working order of its respective society. Philip Pullman’s epic fantasy trilogy, His Dark Materials, uses and manipulates the traditional constructs of the genre to reflect and re-imagine the concepts of adolescence of the late-20^th and early-21^st centuries. Eleven-year-old protagonist Lyra Belacqua and subsequently her cohort, Will Perry, reveal the complications and difficulties modern American and British adolescents experience as …

Freshwater Invertebrate Assimilation Nutrients From Detrital Biofilms Under Light And Phosphorus Manipulation, Taylor Price

Master's Theses

Anthropogenic influences are increasing algal biomass and activity within aquatic ecosystems, stimulating debate regarding interactions between “green” and “brown” food webs. Specifically, in forested streams, the removal of forest canopy or riparian zones increases light exposure and nutrient fluxes to streams affecting primary productivity and carbon (C) flows across aquatic food webs. Further understanding the synergistic effects of light and nutrients on detrital biofilms may explain how aquatic detritivores respond to anthropogenic change. The objective of this study was to employ C and phosphorus (P) isotopic radiolabels to understand how microbial biofilm constituents (i.e heterotroph and autotroph) contribute C and …

Pseudomonas/Brachypodium As A Model System For Studying Rhizosphere Plant Microbe Interactions Under Water Stress, Janiece Mcwilliams

Master's Theses

In contrast to well-studied mechanisms of drought tolerance in plants, the interactions between plants and their microbiome during water stress are still poorly understood. This missing knowledge is crucial for the exploitation of beneficial microbial communities to improve the sustainability of agriculture under changing climatic conditions. The research described here bridged this gap by focusing on the molecular interactions between beneficial rhizobacterium Pseudomonas synxantha 2-79 and annual grass Brachypodium distachyon Bd21. 2-79 exemplifies a group of rhizobacteria associated with dryland wheat, while B. distachyon originates from the Middle East and has emerged as a model for valuable biomass, food, forage, …

Plasmonic Enhancement Of Photoluminescence And Photobrightening In Cdse Quantum Dots, David Alan French

Graduate Theses and Dissertations

Quantum dots are gaining recognition not just in the physics and chemistry community, but in the public eye as well. Quantum dot technologies are now being used in sensors, detectors, and even television displays. By exciting quantum dots with light or electricity, they can be made to emit light, and by altering the quantum dot characteristics the wavelength can be finely tuned. The light emitted can be also be made more intense by an increase in the excitation energy. The excitation light can be increased via plasmonic enhancement, leading to increased luminescence. Aside from the relatively steady-state response, quantum dots …

Where Are All Of Arkansas' Chinquapins? An Ecological Assessment Of Castanea Throughout The State, Logan Pierce Estes

Graduate Theses and Dissertations

Around the turn of the twentieth-century, the chestnut blight fungus (Cryphonectria parasitica) was accidentally introduced into North America. This strong pathogen, which specializes on trees of the genus Castanea, spread rapidly and within half a century had nearly extirpated North America’s Castanea natives from their ranges. During this catastrophe, the American chestnut (Castanea dentata) garnered much of the scientific attention, pushing the other Castanea natives – the chinquapins – to the wayside. More than a century following the spread of the blight, little research into the ecology of North America’s chinquapins had been performed, leaving these trees significantly underrepresented. The …

Evaluation And Characterization Of Fitness Costs In Multiple Herbicide Resistant Echinochloa In Arkansas, Teal Marie Penka

Graduate Theses and Dissertations

Echinochloa spp. are major weed problems for rice (Oryza sativa L.) on a global scale. In the southern rice belt of the U.S.A., Echinochloa colona (L.) Link (junglerice) and E. crus-galli (L.) P. Beauv (barnyardgrass) are the most troublesome weeds. These species are morphologically diverse, and its high ploidy level augurs high genetic diversity, which favors high adaptability to stress, including herbicide selection pressure. The objectives of these studies were to 1) isolate resistant (R) and sensitive (S) biotypes from eight accessions of E. colona with different resistance profiles; 2) determine the resistance levels of selected R and S biotypes …

A Tale Of Two Butterflies: The Effect Of Larval Social Environment And Circadian Rhythms On Mating Behavior In Bicyclus Anynana And Heliconius Hewitsoni, Deonna Nicole Robertson

Graduate Theses and Dissertations

Two key components of mate choice research focus on: 1) who an organism mates with, which may be influenced by any number of factors from sexual ornamentation to male-male competition; and, 2) when an organism courts, be it daily, monthly, or seasonally. Both aspects are especially important for gregarious species as mistakes in either can incur high costs to overall fitness. My research focuses on using butterflies to explore kin recognition from the larval stage and its possible impacts on adult mate choice and if courtship is circadian in Heliconius hewitsoni. My first experiment concerned kin recognition. When inbred, Bicyclus …

Assessment Of Salmonella Enterica Biofilms And Expression Differences Among Serovars, Zhaohao Shi

Graduate Theses and Dissertations

Biofilms are communities of microorganisms associated by a matrix of extracellular polymers. In this state, microorganisms occupy an ecological niche distinct from their free-floating, planktonic counterparts. Also, biofilm bacteria become biologically unique as they form communities and lose motility. The acquisition of these physiological attributes enables the biofilm to persist through harsh environmental conditions, including antimicrobial induced stress and to resist sanitization efforts. Because of these features, biofilms can rapidly disseminate across numerous surfaces and as they establish, become challenging to remove. This is a particular issue for the food industry as processing plants offer favorable conditions for biofilm formation …

Fabrication And Characterization Of Electrochemical Glucose Sensors, Mohammed Marie

Graduate Theses and Dissertations

Electrochemical sensors based on the nanostructure of the semiconductor materials are of tremendous interest to be utilized for glucose monitoring. The sensors, based on the nanostructure of the semiconductor materials, are the third generations of the glucose sensors that are fast, sensitive, and cost-effect for glucose monitoring.

Glucose sensors based on pure zinc oxide nanorods (NRs) grown on different substrates, such ITO, FTO, and Si/SiO2/Au, were investigated in this research. Silicon nanowire (NW)- based glucose sensors were also studied. First, an enzyme-based glucose sensor was fabricated out of glass/ITO/ZnO NRs/BSA/GOx/nafion membrane. The sensor was tested amperometrically at different glucose concentrations. …