Digital Commons Network^™

Broadening The Definition Of Cannabis: An Argument For Speciation Including Indica And Sativa, Winston C. Throgmorton

Southern Illinois University Law Journal

No abstract provided.

Compartmentalization Of Dna-Based Molecular Computing Elements Using Lipid Bilayers, Aurora Fabry-Wood

Biomedical Engineering ETDs

This dissertation will present a progression from the detection of double-stranded DNA using a combination of toehold-mediated strand displacement and DNAzyme reactions in dilute saline solutions, to the generation of separate compartments to allow standardization of DNA computing elements, by protecting from complementary strands. In well-mixed solutions complementary regions cause spurious interactions. Importantly, these compartments also provide protection from nucleases. Along the way we will also explore the use of silica microsphere supported lipid bilayers to run compartmentalized DNA reactions on a fluid surface and the design of a molecule capable of DNA-based transmembrane signal transduction.

Epigenetic Alterations Mediate Ipsc Normalization Of Dna-Repair Expression And Tnr Stability In Huntington's Disease, Peter A. Mollica, Martina Zamponi, John Reid, Deepak Sharma, Alyson E. White, Roy C. Ogle, Robert D. Bruno, Patrick C. Sachs

School of Medical Diagnostics & Translational Sciences Publications

Huntington's disease (HD) is a rare autosomal dominant neurodegenerative disorder caused by a cytosine-adenine-guanine (CAG) trinucleotide repeat (TNR) expansion within the HTT gene. The mechanisms underlying HD-associated cellular dysfunction in pluripotency and neurodevelopment are poorly understood. We had previously identified downregulation of selected DNA repair genes in HD fibroblasts relative to wild-type fibroblasts, as a result of promoter hypermethylation. Here, we tested the hypothesis that hypomethylation during cellular reprogramming to the induced pluripotent stem cell (iPSC) state leads to upregulation of DNA repair genes and stabilization of TNRs in HD cells. We sought to determine how the HD TNR region …

Cc: Connecticut College Magazine, Summer 2018, Connecticut College

Alumni News/Connecticut College Magazine

No abstract provided.

An Evaluation Of Unmanned Aerial System Multispectral And Thermal Infrared Data As Information For Agricultural Crop And Irrigation Management, Mitch Maguire

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Spatial irrigation management has been steadily advancing over the last several years. A current issue with managing irrigation spatially on sub-field scale is the inability to readily collect the spatial field data necessary to properly manage irrigation. Multispectral and thermal infrared imagery used in informing irrigation management decisions was previously collected by satellite and manned aircraft remote sensing platforms. These remote sensing platforms pose issues concerning economic feasibility, revisit intervals, and weather factors that inhibit the collection of data. Recent developments in unmanned aerial systems, which provide an additional means of collecting multispectral and thermal infrared data, have the potential …

Examining The Factors Shaping The Population Structure Of Thalassoma Bifasciatum In The Lemon Keys, Guna Yala, Panama, Nicole Stevens

Independent Study Project (ISP) Collection

Research question

What is the population structure of Thalassoma bifasciatum in the Lemon Keys, Guna Yala, Panama?

Research objective

To examine size class structure of Thalassoma bifasciatum and how its abundance and density vary in relation to factors such as substrate, species diversity and depth.

Sediment Deposition Within Two Thalassia Testudinum Seagrass Sites In Boca Del Drago, Bocas Del Toro Archipelago, Panamá, Alexander De Jesus

Independent Study Project (ISP) Collection

Research Question

Does sediment deposition and composition differ between front and back areas of Thalassia testudinum seagrass beds within two sites on the coast of Boca del Drago, and do these two distinct sites have differences in relative seagrass density and above-ground biomass?

Research Objective

Understand how sediment deposition and sediment composition compare between front and back seagrass areas within two Thalassia testudinum seagrass meadows on the coast of Boca del Drago, and whether the density and above-ground biomass of seagrass identified in each of these two distinct sites also differs.

The Ecology Of The Usambara Double-Collared Sunbird (Cinnyris Usambaricus), Sarah Lueder

Independent Study Project (ISP) Collection

The ecology of the endemic Usambara Double-collared Sunbird (Cinnyris usambaricus) was investigated in the surrounding areas of and within Mazumbai Forest Reserve in the Lushoto District of Tanzania. As there is little known concerning the ecology of the species, this study sought to illuminate multiple aspects of their behavior and interactions. Over fourteen days (November 2nd-November 21st), the abundance of the species, their nesting behavior, their habitat preferences, their vocalizations, their diet, and their aggressive behaviors were observed and then analyzed. It was determined the species’ activity likely peaks in the early morning, their nesting is similar to other species …

Editor's Letter

Wraparound South (Archived)

No abstract provided.

Toxic Machismo, Identity, And Heritage In The Southwest – An Interview With Jose Skinner, Laura Valeri

Wraparound South (Archived)

No abstract provided.

Post-Traumatic Stress Disorder And Cardiovascular Diseases: A Cohort Study Of Men And Women Involved In Cleaning The Debris Of The World Trade Center Complex, Molly Remsch, Zoey Laskaris, Janine D. Flory, Consuelo Mora-Mclaughlin, Alfredo Morabia

Publications and Research

BACKGROUND: To determine whether post-traumatic stress disorder (PTSD) is a risk factor for myocardial infarction (MI) and stroke, beyond the expected effects from recognized cardiovascular risk factors and depression.

METHODS AND RESULTS: World Trade Center-Heart is an observational prospective cohort study of 6481 blue-collar first responders nested within the World Trade Center Health Program in New York City. Baseline measures in 2012 and 2013 included blood pressure, weight and height, and blood lipids. PTSD, depression, smoking, and dust exposure during the 2001 cleanup were self-reported. During the 4-year follow-up, outcomes were assessed through (1) interview-based incident, nonfatal MI, and stroke, …

Exploring Empathy In Medical Narratives, Adam Uhrig

All NMU Master's Theses

No abstract provided.

Und Today: July 2018, University Of North Dakota

UND Today Archive

No abstract provided.

Vol. 43, No. 2: Summer 2018, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

Examining The Association Of Environmental Degradation And Poor Cardiovascular And/Or Respiratory Health Outcomes In A Disadvantaged Community, Khyati Niranjan Kantaria

Health Services Research Dissertations

Air pollution is associated with poor cardiovascular and/or respiratory health outcomes. The poor air quality in certain communities due to the emission of toxic air pollutants from industries and major roadways has been a growing concern. The main objective of this study was to examine whether residential proximity to environmental air pollution sources, individual-level risk factors (age, gender, and body mass index (BMI)) and number of years at same residence are associated with observed poor cardiovascular and/or respiratory health outcomes in the residents of Southeast community in Newport News, Virginia. Logistic regression was conducted to assess this association using the …

Surgical And Medical Applications Of Drones: A Comprehensive Review, Brent Terwilliger, James C. Rosser Jr., Vudatha Vignesh, Brett C. Parker

Publications

Drones have the ability to gather real time data cost effectively, to deliver payloads and have initiated the rapid evolution of many industrial, commercial, and recreational applications. Unfortunately, there has been a slower expansion in the field of medicine. This article provides a comprehensive review of current and future drone applications in medicine, in hopes of empowering and inspiring more aggressive investigation.

The Impact Of Violence On The Emerging Development Of Emotion Regulation: The Role Of The Caregiver, Christina Caiozzo

Dissertations (1934 -)

Caregivers teach children how to navigate an emotional world (Thompson, 1994), and children’s ability to manage emotional reactions underlies their mental health as well as their social and academic performance (Zeman, Cassano, Perry-Parish, & Stegall, 2006). However, children who experience adverse life events are at risk for impaired development of emotion regulation (Maughan & Cicchetti, 2002). Little is known about how parents of at-risk youth can continue to foster healthy development of emotion regulation for their children. Therefore, the current study aims to identify specific parenting practices that promote adaptive emotion regulation in at-risk preschoolers. Multi-method, multi-informant data were collected …

Design, Synthesis And Study Of Redox And Optoelectronic Properties Of Aromatic Oxidants And Polycyclic Aromatic Hydrocarbons, Mohammad Mosharraf Hossain

Dissertations (1934 -)

Organic materials play a significant role for the next generation photovoltaic devices that convert solar energy into usable forms of energy. In this regard, polycyclic aromatic hydrocarbons (PAHs) are fundamental tools in the developing area of molecular electronics and photovoltaics as they show excellent optical/electronic properties and are well-suited for applications in such developing areas as flexible display devices, field effect transistors and solar cell panels. Design and synthesis of novel materials for photovoltaics applications would require the proper understanding the mechanism of charge transport and identification of the structural features necessary in a particular molecular wire or PAH. To …

Plants And Their Uses; How Communities Of Tolipir, Pakistan Get Benefit, Abu Ul Hassan Faiz, Mehboob Ul Hassan, Fida Muhammad Khan, Lariab Zahra Faiz, Hina Farooq

Journal of Bioresource Management

The present study documented ethnobotanical uses of 156 plant species belonged to 93 genera and 51 families listed from five villages of Tolipir landscape (Ali Sojhal, Kanchi Kot, Khori Chana, Kahoo Kot and Noor Kot villages). Study revealed that most of the species were used medicinally, leaves found to be the most frequently used part, for preparation of indigenous recipes and fodder purpose. The current study empirically contributes a huge chunk of ethnobotanical knowledge and depicts its strong connection with indigenous traditions. It is an urgent need to document indigenous uses of plants for future domestication.

Oaks (Family: Fagaceae) Diversity From Moist Temperate Forests Of Lesser Himalayas, Pakistan, Sher Wali, Kishwar Sultana, Fida Muhammad Khan

Journal of Bioresource Management

A detailed survey was conducted in five national parks and game reserves of Azad Jammu and Kashmir, Pakistan to assess the biodiversity of family Fagaceae. Identification of the species was done using literary sources and comparison of samples with herbaria from Quaid-i-Azam University, Islamabad and Pakistan Museum of Natural History, Islamabad, Pakistan. A total of eight different species belonging to two genera were identified, including Quercus spp., Castanea sativa, Quercus glauca, Quercus baloot, Quercus incana, Quercus velutina, Quercus alba and Quercus dilatata. The greatest biodiversity was found in Banjosa Game Reserve (BGR) and Tolipir National Park (TNP), while Pir …

Inference And Analysis Of Multilayered Mirna-Mediated Networks In Cancer, Duc Do

Dissertations (1934 -)

MicroRNAs (miRNAs) are small noncoding transcripts that can regulate gene expression, thereby controlling diverse biological processes. Aberrant disruptions of miRNA expression and their interactions with other biological agents (e.g., coding and noncoding transcripts) have been associated with several types of cancer. The goal of this dissertation is to use multidimensional genomic data to model two different gene regulation mechanisms by miRNAs in cancer. This dissertation results from two research projects. The first project investigates a miRNA-mediated gene regulation mechanism called competing endogenous RNA (ceRNA) interactions, which suggests that some transcripts can indirectly regulate one another's activity through their interactions with …

Understanding Relationships Between Early Life Toxic Stress, Childhood Socioeconomic Disadvantage, And Allostatic Load In Adolescence, Amanda King

Dissertations (1934 -)

Chronic disease prevalence among children and adolescents is rising, which is thought to result in part from elevations in allostatic load (AL). AL is the cumulative physiological dysregulation that results from exposure to biological, social and environmental stressors over time. Socioeconomic disparities in chronic disease and AL have been well-documented in adult populations, including links between childhood socioeconomic disadvantage (CSD) and AL, yet little is known as to whether CSD may begin to impact AL earlier in life. Differential exposure and vulnerability to stress among racial/ethnic minorities may increase risk for elevated AL among those experiencing CSD. Framed by the …

The Forbidden Zone Writers: Femininity And Anglophone Women War Writers Of The Great War, Sareene Proodian

Dissertations (1934 -)

This dissertation examines the texts of Anglophone women writers from the First World War. Women’s roles in the war—volunteer nurses, ambulance driver, munitions workers, and land girls—gave them the opportunity to leave the protection of their homes and enter the masculine dominated public sphere. In this dissertation, I examine different genres of women’s writing from the war and trace three aspects of simultaneity as these writings explore the new freedoms, and new and old constraints, that the war brought to women. The three principles of simultaneity explain the conflicting emotions women feel over what the war means for them in …

Pre-Death Grief, Resourcefulness And Perceived Stress Among Care Givers Of Partners With Young Onset Dementia, Karie Kobiske

Dissertations (1934 -)

Over 200,000 Americans are diagnosed with young onset dementia (YOD). YOD is the dementia diagnosed prior to the age of 65. Most persons of YOD are cared for by their partners. Caregiving for a partner diagnosed with YOD has unique challenges including multiple losses resulting from the functional, cognitive, and behavioral declines which can be demanding and stressful. These losses experienced by the caregiver of a partner diagnosed with YOD have been termed pre-death grief. Caregivers of partners with YOD often report high levels of burden and stress resulting in depression, anxiety, hopelessness, as well as increase morbidity and mortality. …

The Role Of Small Ruminants On Global Climate Change, Alda Lúcia Gomes Monteiro, Amanda Moser Coelho Da Fonseca Faro, Mylena Taborda Piquera Peres, Rafael Batista, Cesar Henrique Espirito Candal Poli, Juan J. Villalba

Wildland Resources Faculty Publications

Global warming, as a consequence of excessive CO2 production mainly due to anthropogenic actions, is one of the main concerns of society due to the effects it can cause in the survival of humans, plants and animals. Several climatic consequences have already been reported, such as warming the oceans and changing biodiversity in various regions of the planet. One of the greenhouse gases responsible for global warming, which causes a lot of concern, is methane gas from digestion of food by ruminants. Besides that, emissions of greenhouse gases are represented also by waste management, rice cultivation, burning of residues from …

Climatic Drivers Of Ponderosa Pine Growth In Central Idaho, Joseph L. Pettit, R. Justin Derose, James N. Long

Wildland Resources Faculty Publications

Despite the widespread use of ponderosa pine as an important hydroclimate proxy, we actually understand very little about its climate response in the Northern Rockies. Here, we analyze two new ponderosa pine chronologies to investigate how climate influences annual growth. Despite differences in precipitation amount and timing and large elevation differences (1820 m versus 1060 m), ring width at both sites was strongly driven by water availability. The mid-elevation, water-limited site responded well to previous fall precipitation whereas the wetter, high-elevation site responded to growing season precipitation and temperature. When precipitation and temperature were simultaneously accounted for using the standardized …

Reducing Urban Pollution From Coastal Settlements With Green Roofs, Alexander Phillips

The Plymouth Student Scientist

It was identified that traditional infrastructural methods for solving coastal pollution were becoming too costly and insufficient in combatting the effects of climate change. This report investigates the sustainable drainage method of green roofing as a possible approach to reducing coastal pollution. A generic computational hydraulic model was created, using Plymouth as a design template, to represent 3 different scenarios in which a combined sewage system would require overflow relief. Storm simulations were run through the scenarios to determine a set of baseline sewage spilling results. The simulations were rerun after allowances for green roofs, with substrates of 50mm and …

How Does Individual Quality And Mate Attractiveness Affect Courtship And Mating Behaviour?, Laura Cook

The Plymouth Student Scientist

Courtship and mating are costly and as a result, organisms are faced with trade-off decisions between the costs and benefits which arise from them. Individuals use information on their own quality and the attractiveness of their potential mate to determine whether to court and mate, and if so how much energy to invest in these activities. An individual’s quality can affect its ability to perform sexual activities and determine the energy the individual is able to invest in such activities. Organisms assess one another on their relative attractiveness, which allows them to determine the relative benefits they will receive from …

Bioethics (Gcsu), Kasey Karen, Jennifer Townes

Biological Sciences Grants Collections

This Grants Collection for Bioethics was created under a Round Ten ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Trichomonas Vaginalis Cytoadherence Is Modulated By Oxidative Stress, Magali Ayala

Theses and Dissertations

The adherence of Trichomonas vaginalis to the human urogenital tract is a prerequisite for the pathogenesis of the infection. This multifactorial process is modulated by environmental factors such as iron, estrogen, temperature and pH and specific receptor/ligand interactions. During natural infections, the anaerobe T. vaginalis is exposed to oxygen resulting in oxidative stress. This environmental change may alter trichomonad cytoadherence to the ectocervical tissue. Therefore, it was hypothesized that changes in the redox status of T. vaginalis may modulate cytoadherence levels. Results showed that oxidative stress reduces levels of trichomonad cytoadherence to HeLa cells by > 50% when exposed to 150 …