Digital Commons Network^™

Community-Scale Water Treatment Systems In The Dominican Republic, Jonathan Racey, Annabelle Papai, Elise Fischer, Becca Johnson

Engagement & Service-Learning Summit

Engagement and Service-Learning Summit: Reciprocal and Sustainable Partnerships

The Social Context Of Women's Sustained Participation In Activism, Susan Paterson

Open Access Dissertations

Recently, the resurgence of interest in feminist activism has been discussed by media and news outlets. It is still relatively unknown what contextual factors affect sustained participation, as well as how women from different backgrounds sustain activism in the face of compounding oppressions. This grounded theory explores the contexts of sustained participation through two research questions: (1) what are the contextual factors that influence women's sustained participation in activism?, and (2) how is the dynamic between identity and context reflected in sustained participation in activism? Nine women activists in Miami-Dade County were interviewed about their experiences in feminist movements, specifically …

Polycomb Complexes Associate With Enhancers To Regulate Oncogenic Pathways In Cancer, Ho Lam (Candy) Chan

Open Access Dissertations

The Polycomb repressive complexes play diverse and essential roles in cell fate decisions, embryonic development, stem cell pluripotency, and gene regulation. There are two main Polycomb complexes in mammalian cells, Polycomb Repressive Complex 1 and 2 (PRC1 and PRC2). PRC1 can be further subdivided into canonical and non-canonical complexes depending on its composition (cPRC1 and ncPRC1). Historically, Polycomb complexes have been mostly associated with maintaining gene repression carried out by its histone-modifying and chromatin-remodeling capabilities. Specifically, PRC1 can catalyze mono-ubiquitination of histone H2A on lysine 119 while PRC2 trimethylates histone H3 on lysine 27. Both these histone marks are associated …

How Does The New Urban Agenda Align With Comprehensive Planning In U.S. Cities? A Case Study Of Asheville, North Carolina, Matthew Cohen, Geoffrey Habron

Earth and Environmental Sciences Publications

Despite growing interests in sustainable urban development, planning lacks unifying themes or directives for achieving sustainability in cities. While professional rating systems provide some guidance, they can be context-specific by country and may at best target weak sustainability as their intended outcome. The United Nations’ New Urban Agenda attempts to offer a singular vision for urban sustainability, and its language appears flexible enough to apply across contexts. In this research, we explore the extent that emergent themes from the New Urban Agenda can guide urban planning for sustainability, specifically in the United States (U.S.). We develop inductive codes from the …

The Baffling Connection Between Vegetarianism And Depression, Harold Herzog

'Animals and Us' Blog Posts

New research connects vegetarianism and depression. The question is why?

Population Genomic Analysis Of North American Eastern Wolves (Canic Lycaon) Support Their Conservation Priority Status, Elizabeth Heppenheimer, Ryan Harrigan, Linda Rutledge, Klaus-Peter Koepfli, Alexandra L. Decandia, Kristin Brzeski, Et. Al.

College of Forest Resources and Environmental Science Publications

The threatened eastern wolf is found predominantly in protected areas of central Ontario and has an evolutionary history obscured by interbreeding with coyotes and gray wolves, which challenges its conservation status and subsequent management. Here, we used a population genomics approach to uncover spatial patterns of variation in 281 canids in central Ontario and the Great Lakes region. This represents the first genome-wide single nucleotide polymorphism (SNP) dataset with substantial sample sizes of representative populations. Although they comprise their own genetic cluster, we found evidence of eastern wolf dispersal outside of the boundaries of protected areas, in that the frequency …

Ua12/2/1 Class Of 2018 Fall Graduates, Wku Student Affairs

WKU Administration Documents

Magazine edition of the College Heights Herald featuring December graduates.

• Commencement Schedule
• Gordon Ford College of Business
• Potter College of Arts & Letters
• Ogden College of Science & Engineering
• College of Education & Behavioral Sciences
• College of Health & Human Services

How Soil Salinity Affects The Stomatal Conductance Of Baccharis Salicifolia (Mulefat/Seepwillow), Andrew Kim, Caroline Wilkerson, Mahala Bayless, Peter Du

Featured Research

This is a poster presentation demonstrating the project our group has been working on. We hypothesize that the stomatal conductance of mulefat will decrease as soil salinity increases in both pre-rain and post-rain conditions because the plant tries to absorb salt water. However, the salt water cannot pass through plant tissue and draws water out of the plant. Since plant requires water for photosynthesis, water being drawn out means less water is available for the plant to do photosynthesis. We have tested our hypothesis by collecting soil samples in Legacy park, and recorded stomatal conductance by using a leaf porometer

A Comparison Of Different Methods Of Dehydration On Baccharis Salicifolia, Michael Nicholas, Sinjun Hong

Featured Research

Baccharis salicifolia is a native riparian plant living in many places near to the Santa Monica Mountains. One of these locations is Legacy park, which has had many events effect it that has led to some very unfortunate changes. The park’s soil was tested earlier this year by a group of undergraduate students lead by Dr. Stephen Davis and was found to have a very high salinity level. The plants in the park appeared to be struggling to survive and had signs of dehydration and wilting. This led to us questioning the types of dehydration of the plants. Areas of …

A Comparison Of Photosynthetic Rate, Stomatal Conductance, And 
Electron Transport Rate Between Malosma Laurina And Encelia Californica, Yujin Choi, Isabella Armstrong, Catherina Haas, Micah Kim

Featured Research

In the Santa Monica Mountains, there are two main vegetation types: chaparral, which makes up __% of plants in these mountains, and coastal sagebrush, which makes up __%. Despite California’s acute environmental stress, both of these plants manage to survive, and even thrive in some cases. We were interested in seeing if in spite of these vast anatomical and physiological differences, these plants were able to survive at similar health rates, measured in photosynthetic rate, stomatal conductance, and electron transport rate (ETR). We have decided to choose 2 plants from 2 different leaf types of different vegetation types: Malosma laurina …

Ua12/2/1 College Heights Herald, Vol. 94, No. 14, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Heichelbech, Evan. Thanks for Reading Another Eventful Semester of News
• Austin, Emma. Earth Science Education Sees Drop, Says Research Institute
• DeLetter, Emily. Ramping Up – Enrollment
• Ziege, Nicole. Title IX Committee Stalls Completion of Investigation
• Dobbs, Jack. White Supremacist Organization Recruiting on Campus – Evropa
• Ceballo, Ivy. From Broken & Bruised to Free & Strong – Domestic Abuse
• Allen, Ellie. Editorial Cartoon – WKU White Squirrel with Christmas Gift
• Ho Ho Herald: The Herald’s 2018 Christmas Gifts
• Kohley, Chris. Sunshine Skate – SoKY Ice Rink …

Kuchta Gets Rakowski Award For Outstanding Research In Biological Sciences, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Decoration Of Nanovesicles With Ph (Low) Insertion Peptide (Phlip) For Targeted Delivery, Federica Rinaldi, Patrizia N. Hanieh, Elena Del Favero, Valeria Rondelli, Paola Brocca, Mohan C. Pereira, Oleg A. Andreev, Yana K. Reshetnyak, Carlotta Marianecci, Maria Carafa

Physics Faculty Publications

Acidity at surface of cancer cells is a hallmark of tumor microenvironments, which does not depend on tumor perfusion, thus it may serve as a general biomarker for targeting tumor cells. We used the pH (low) insertion peptide (pHLIP) for decoration of liposomes and niosomes. pHLIP senses pH at the surface of cancer cells and inserts into the membrane of targeted cells, and brings nanomaterial to close proximity of cellular membrane. DMPC liposomes and Tween 20 or Span 20 niosomes with and without pHLIP in their coating were fully characterized in order to obtain fundamental understanding on nanocarrier features and …

How Soil Salinity Affects The Stomatal Conductance Of Baccharis Salicifolia (Mulefat/Seepwillow), Andrew Kim, Caroline Wilkerson, Mahala Bayless, Peter Du

Featured Research

This is a poster presentation demonstrating the project our group has been working on. We hypothesize that the stomatal conductance of mulefat will decrease as soil salinity increases in both pre-rain and post-rain conditions because the plant tries to absorb salt water. However, the salt water cannot pass through plant tissue and draws water out of the plant. Since plant requires water for photosynthesis, water being drawn out means less water is available for the plant to do photosynthesis. We have tested our hypothesis by collecting soil samples in Legacy park, and recorded stomatal conductance by using a leaf porometer

Comparison Of Photosynthesis, Stomatal Conductance, And Water Potential Between Native Rhus Integrifolia And Invasive Nicotiana Glauca, Tiffany J. Egbo, Emma J. Navarro, Malaun A. Phillips, Cameron I. Zohary

Featured Research

Invasive species, such as Nicotiana glauca, are a prominent part of the Santa Monica Mountains, and could be responsible for displacing native species such as Rhus integrifolia. It was observed in the field that Nicotiana glauca was doing better than Rhus integrifolia, so our group decided to indirectly test this. Because of the invasiveness of its species, it is essential to measure the health of a native species to see if the invasive species is posing as a massive threat. Water potential, stomatal conductance, fluorescence, photosynthetic rates and electron transport rates were compared among the two plants …

Optimization Of Light Irradiance During The Early Life Of Sexually-Produced Porites Astreoides And Agaricia Agaricites Recruits, Nicholas J. Mcmahon

HCNSO Student Theses and Dissertations

Current solutions of coral restoration rely mainly on fragmentation. Though a reliable technique, this asexual form of reproduction does not benefit the genetic diversity of the coral reef. With many global and local stressors threatening corals’ existence, the resiliency of corals to future ocean conditions depends highly on sexual reproduction to produce new genotypes. New technology allows coral spawning/larval release, larval settlement and rearing to be carried out in an aquarium system. Many of the techniques necessary to maintain coral recruits are well-established, however the effects of light intensity remain to be studied for these early life stages. Newly …

Empirical Validation And Comparison Of The Hybrid Coordinate Ocean Model (Hycom) Between The Gulf Of Mexico And The Tongue Of The Ocean, Cynthia A. Cleveland

HCNSO Student Theses and Dissertations

Ocean models are increasingly able to synthesize a large temporal domain with fine spatial resolution. With this increase in functionality and availability, ocean models are in high demand by researchers, establishing a critical need for validating a model’s ability to represent interior ocean dynamics. Satellite measurements are typically used for validation, however these measurements are limited to the upper layers of the ocean and therefore satellite measurements of sea surface height and sea surface temperature are the most validated output parameters of three-dimensional ocean models. Unfortunately there is a paucity of model validation studies for the interior ocean. This study …

Sitc 2018 Workshop Report: Immuno-Oncology Biomarkers: State Of The Art., Lisa H Butterfield, Mary L Disis, Bernard A Fox, David R Kaufman, Samir N Khleif, Ena Wang

Articles, Abstracts, and Reports

Identification of biomarkers in cancer immunotherapy that predict therapeutic response and/or limit adverse events are a critical need in the field. To address recent progress and hurdles around cancer biomarker development and utilization, the Society for Immunotherapy of Cancer (SITC) convened a workshop, "Immuno-Oncology Biomarkers: State of the Art," on May 16-17, 2018. Topics discussed included challenges in handling biospecimens, identification and validation of new biomarkers, data sharing, and collaborating across disciplines to advance biomarker development. Panel discussions followed session presentations to help foster participant conversation and discuss future projects and collaborations. The results of the Workshop include the development …

Targeting The Stat5 Pathway In Ph+ Acute Lymphoblastic Leukemia, Valentina Minieri, Marco De Dominici, Marja T. Nevalainen, Bruno Calabretta

Department of Cancer Biology Faculty Papers

No abstract provided.

2018 December 4, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, December 4, 2018

Minimal Influence Of Extracellular Dna On Molecular Surveys Of Marine Sedimentary Communities, Gustavo A. Ramírez, Steffen L. Jørgensen, Rui Zhao, Steven D’Hondt

Graduate School of Oceanography Faculty Publications

Extracellular DNA has been reported to comprise a large fraction of total DNA in near-seafloor sediment. However, the potential effect of extracellular DNA, arising from dead or moribund cells, on sequencing surveys is a critical concern that has largely not been addressed for marine sedimentary habitats. To address this concern, we interrogated freshly collected Arctic and Pacific sediment for extracellular 16S rRNA genes using the photoactive DNA-binding dye Propidium Monoazide. Significant differences between relative abundances of total (intracellular + extracellular) Bacterial 16S rRNA genes and relative abundances of intracellular Bacterial 16S rRNA genes are only detected in three of twelve …

Nanocapsules On A Lipid Membrane, Zain-Al-Abidin Shahid Kinnare

Electronic Theses and Dissertations Archive

Nanoparticle technology is gaining traction in many different industries, particularly in imaging and the medical industries, and thus it becomes increasing important to understand how particles will affect the body. This is why we want to look at the way nanoparticles interact with lipid membranes, since lipids play vital roles in biological processes such as stabilizing the distal airways in our lungs in low volume situations. Knowing how nanoparticles will interact with these lipids can give us insights into the potentials cytotoxicity of the particles, and how other agents, such as viruses act near/on a lipid membrane. In thisthesis, we …

Trustworthiness Appraisal Deficits In Borderline Personality Disorder Are Associated With Prefrontal Cortex, Not Amygdala, Impairment, Eric A. Fertuck, Jack Grinband, J. John Mann, Joy Hirsch, Kevin Ochsner, Paul Pilkonis, Jeff Erbe, Barbara Stanley

Publications and Research

Background

Borderline Personality Disorder (BPD) is associated with sensitivity to signals of interpersonal threats and misplaced trust in others. The amygdala, an integral part of the threat evaluation and response network, responds to both fear- and trust-related stimuli in non-clinical samples, and is more sensitive to emotional stimuli in BPD compared to controls. However, it is unknown whether the amygdalar response can account for deficits of trust and elevated sensitivity to interpersonal threat in BPD.

Methods

Facial stimuli were presented to 16 medication-free women with BPD and 17 demographically-matched healthy controls (total n = 33). Participants appraised fearfulness or trustworthiness …

γ-Aapeptides With Potent And Broad-Spectrum Antimicrobial Activity, Jianfeng Cai, Youhong Niu, Haifan Wu, Shruti Padhee

USF Patents

The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides, cyclic γ-AApeptides, and lipidated γ-AApeptides. γ-AApeptides of the current invention are designed to exert antimicrobial activity while being stable and non-toxic. γ-AApeptides also do not appear to lead to the development of microbial resistance in treated microorganisms. Thus, the disclosed γ-AApeptides can be used for the treatment of various medical conditions associated with pathogenic microorganisms.

Antimicrobials From An Epigenetics Based Fungal Metabolite Screening Program, Danielle H. Demers, Bill J. Baker, Ala Azhari, Renee M. Fleeman, Dennis E. Kyle, Lindsey Neil Shaw

USF Patents

Novel antimicrobial compounds against drug targets such as Eskape pathogens, Leishmania donovani, Mycobacterium tuberculosis, Clostridium difficile, Naegleria fowleri, and cancer are presented herein.

Method For The Treatment Of Malignancies, Richard Heller, Kenneth E. Ugen

USF Patents

A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently administering at least one high voltage, short duration pulse to the tumor. The electroporation pulses may be administered at at least 700V/cm for a duration of less than 1 millisecond. The intratumor treatments with electroporation may be administered in at least a two-treatment protocol with the time between treatments being about 7 days. The intratumor treatments with electroporation may be administered in a three-treatment protocol with a time of …

Loss Of Intellectual Functioning In Cerebrovascular Vs Alzeheimer's Disease, Christina Bhawanidin, Eliza Gonzalez, Illhom Bakiyev

Publications and Research

Aim

To compare loss of intellectual functioning in cerebrovascular (CVA) vs. Alzheimer’s disease (AD).

Method

Subjects had Psychiatric disorders (n=26), CVA (n=37), or AD (n=27). Expected premorbid intellectual functioning was computed using educational attainment. Intellectual ability was separated into deviation quotients for Verbal-Conceptual, Attention-Concentration, or Perceptual-Constructional ability, and Psychomotor Speed. The difference between obtained and expected intellectual functioning in each cognitive domain was analyzed using a repeated measures ANOVA with age as a covariate.

Contrasting Population Genetic Structure In Three Aggregating Groupers (Percoidei: Epinephelidae) In The Indo-West Pacific: The Importance Of Reproductive Mode, Ka Yan Ma, Lynne Van Herwerden, Stephen J. Newman, Michael L. Berumen, John Howard Choat, Ka Hou Chu, Yvonne Sadovy De Mitcheson

Fisheries Research Articles

Background

Understanding the factors shaping population genetic structure is important for evolutionary considerations as well as for management and conservation. While studies have revealed the importance of palaeogeographic changes in shaping phylogeographic patterns in multiple marine fauna, the role of reproductive behaviour is rarely considered in reef fishes. We investigated the population genetics of three commercially important aggregating grouper species in the Indo-West Pacific, namely the camouflage grouper Epinephelus polyphekadion, the squaretail coral grouper Plectropomus areolatus, and the common coral trout P. leopardus, with similar life histories but distinct spatio-temporal characteristics in their patterns of forming spawning aggregations. …

Impact Of Copper And Iron Binding Properties On The Anticancer Activity Of 8-Hydroxyquinoline Derived Mannich Bases., Veronika F.S. Pape, Nóra V. May, G. Tamás Gál, István Szatmári, Flóra Szeri, Ferenc Fülöp, Gergely Szakács, Éva A. Enyedy

Department of Dermatology and Cutaneous Biology Faculty Papers

The anticancer activity of 8-hydroxyquinolines relies on complex formation with redox active copper and iron ions. Here we employ UV-visible spectrophotometry and EPR spectroscopy to compare proton dissociation and complex formation processes of the reference compound 8-hydroxyquinoline (Q-1) and three related Mannich bases to reveal possible correlations with biological activity. The studied derivatives harbor a CH2-N moiety at position 7 linked to morpholine (Q-2), piperidine (Q-3), and chlorine and fluorobenzylamino (Q-4) substituents. Solid phase structures of Q-3, Q-4·HCl·H2O, [(Cu(HQ-2)2)2]·(CH3OH)2·Cl4·(H2O)2, [Cu(Q-3)2]·Cl2 and [Cu(HQ-4)2(CH3OH)]·ZnCl4·CH3OH were characterized by single-crystal X-ray diffraction analysis. In addition, the redox properties of the copper and iron complexes …

Chemical And Biological Studies Of Cannabis Sativa Roots, Mostafa Elhendawy, Amira S. Wanas, Mohamed M. Radwan, N. Azzaz, Elshahat S. Toson, Mahmoud A. Elsohly

Faculty and Student Publications (Open Access)

No abstract provided.