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Transport Of Bmaa Into Neurons And Astrocytes By System XC-, Rebecca Albano, Doug Lobner

Biomedical Sciences Faculty Research and Publications

The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated. First, there are certain cell types, such as motor neurons and cholinergic neurons, where the dominate mechanism of toxicity is through action at AMPA receptors. Second, even in cortical neurons where the primary mechanism of toxicity appears to be activation of NMDA receptors, there are other mechanisms involved. We found that along with NMDA receptors, activation of mGLuR5 receptors and effects on the …

What Does The Fos Say? Using Fos-Based Approaches To Understand The Contribution Of Stress To Substance Use Disorders, Jayme R. Mcreynolds, John P. Christianson, Jordan M. Blacktop, John Mantsch

Biomedical Sciences Faculty Research and Publications

Despite extensive research efforts, drug addiction persists as a largely unmet medical need. Perhaps the biggest challenge for treating addiction is the high rate of recidivism. While many factors can promote relapse in abstinent drug users, the contribution of stress is particularly problematic, as stress is uncontrollable and pervasive in the lives of those struggling with addiction. Thus, understanding the neurocircuitry that underlies the influence of stress on drug seeking is critical for guiding treatment. Preclinical research aimed at defining this neurocircuitry has, in part, relied upon the use of experimental approaches that allow visualization of cellular and circuit activity …

17Β-Estradiol Potentiates The Reinstatement Of Cocaine Seeking In Female Rats: Role Of The Prelimbic Prefrontal Cortex And Cannabinoid Type-1 Receptors, Elizabeth M. Doncheck, Luke A. Urbanik, Margot C. Debaker, Laura M. Barron, Gage T. Liddiard, Jennifer J. Tuscher, Karyn M. Frick, Cecilia J. Hillard, John Mantsch

Biomedical Sciences Faculty Research and Publications

Clinical observations imply that female cocaine addicts experience enhanced relapse vulnerability compared with males, an effect tied to elevated estrogen phases of the ovarian hormone cycle. Although estrogens can enhance drug-seeking behavior, they do not directly induce reinstatement on their own. To model this phenomenon, we tested whether an estrogen could augment drug-seeking behavior in response to an ordinarily subthreshold reinstatement trigger. Following cocaine self-administration and extinction, female rats were ovariectomized to isolate estrogen effects on reinstatement. Although neither peak proestrus levels of the primary estrogen 17β-estradiol (E2; 10 μg/kg, i.p., 1-h pretreatment) nor a subthreshold cocaine dose …

Unveiled Faces: The Heavenly Counterpart Traditions In Joseph And Aseneth, Andrei Orlov

Theology Faculty Research and Publications

From one of the Manichaean psalms we learn that in the final moments of his life Mani was beholding his heavenly double with “eyes of light.” This was not the only encounter this Syrian visionary had with his upper celestial identity. The Cologne Mani Codex tells us that the heavenly counterpart first manifested himself to Mani at the age of twelve and he continued his visits, to assist with revelations, until Mani’s death. In several texts Mani’s celestial alter ego is designated as a spirit and even called the Paraclete, the same title the Holy Spirit bears in the Fourth …

Audiation And Improvisation As They Relate To Synesthesia In The Organ Music Of Olivier Messiaen, Mark Konewko

College of Communication Faculty Research and Publications

The purpose of this article is to explore the relationship between audiation, improvisation, and synesthesia in the music of Olivier Messiaen. “When I hear a score or read it, hearing it in my mind, I visualize corresponding colors which turn, shift, and combine, just as the sounds turn, shift, and combine, simultaneously” (Samuel 1986: 37). The function of audiation, synesthesia and improvisation are manifest in the creative procedure of Messiaen’s in compositions. Messiaen “audiates” in his compositions the sensation of color. Harmonic configurations that Messiaen utilizes his fashioned Modes of Limited Transposition that dictate particular harmonic colors. For Messiaen and …

Testing Links Among Uncertainty, Affect, And Attitude Toward A Health Behavior, Robert J. Griffin, Timothy K.F. Fung, Sharon Dunwoody

College of Communication Faculty Research and Publications

This study examines the conceptual linkages between individuals’ uncertainty judgments and affective reactions (worry and anger) within the context of an environmental health risk. It uses data from a longitudinal study of people’s reactions to the risks of eating contaminated fish from the Great Lakes that employed the risk information seeking and processing model and incorporates a set of variables from the full model, which includes preventive behavior. Findings support the model and indicate that worry and anger strongly influenced uncertainty judgments but worry and anger influenced attitudes toward fish avoidance and information insufficiency differently.

Invited Essay: Investigating Family Voices From The Margins, Lynn H. Turner, Richard West

College of Communication Faculty Research and Publications

This essay surveys articles from the Journal of Family Communicationto make the argument that our journal needs to feature more scholarship on families that heretofore have been virtually ignored or marginalized. We discuss four types of diversity to consider when exploring questions of family communication, and review three imperatives for making this argument.

A Secret Police: The Lasting Impact Of The 1986 Foia Amendments, A.Jay Wagner

College of Communication Faculty Research and Publications

The 1986 Freedom of Information Act amendments were passed as a last-minute rider to Reagan-era War on Drugs legislation. The three pieces – a broad restructuring of Exemption 7, the law enforcement exemption; the addition of exclusions for law enforcement and intelligence requests; and introduction of a new fee structure – have had a lasting impact on FOIA implementation and contribute to the contemporary inability to affect police transparency. Review of the 1986 FOIA amendments’ legislative history documents the White House’s determination to loosen law enforcement oversight and congressional appeals to exaggerated fears of illicit drug users. The study considers …

Evaluation Of New Teacher Adjustment Factors In International Schools In Thailand To Improve Teacher Retention, Rekha Sachdej

Theses and Dissertations

This applied dissertation was aimed to provide updated information in regards to new teacher’s adjustment factors in a small international school setting in Thailand. With the rapid increase in international schools in Thailand, the demand for quality education and instructions has also increased due to competition between schools. Retaining good teachers is one important aspect in providing quality education, in particular new teachers. Studies have shown new teachers are at high risk of leaving the school or even leaving the teaching career within their first five years of teaching (Haynes, 2014; Phillips, 2015). However, little research exists in regards to …

Teachers’ Experiences In A Charter School With English Language Learners’ Acquisition Of Academic Literacy, Estella Stephens

Theses and Dissertations

Teachers’ Experiences in a Charter School With English Language Learners’ Acquisition of Academic Literacy. Estella Stephens, 2018: Applied Dissertation, Nova Southeastern University, Abraham S. Fischler College of Education. Keywords: charter schools, English language learners, literacy, phenomenon, qualitative research, teachers.

This qualitative applied dissertation was designed to investigate and give voice to the lived experiences of mainstream teachers at charter schools where the English language learner (ELL) population increased significantly. It replicated McCoy’s (2013) study. A phenomenological design was used to interview kindergarten-Grade 8 mainstream teachers in 3 charter schools. Interviews were conducted by a noninterested party due to the positionality …

Elementary Charter School Teachers' Perceptions Of Student Discipline On Academic Achievement, Simone Elloie Shelton

Theses and Dissertations

Many teachers leave the field altogether after a few years of teaching. Research showed that teachers consistently rate the behavior problems of their students as one of the primary reasons for them to quit teaching. Among teachers who have left the field over the past 10 years, some 80% stated that discipline problems caused by students was one of the primary reasons for their departure. Student discipline has been reported as a factor associated with high rates of teachers leaving the teaching profession. Two studies of teacher attrition rates found that problems with students’ discipline issues and classroom management issues …

Factors Affecting Adult Speakers Of Other Languages' (Esol) Enrollment In English For Academic Purposes (Eap) Courses: A Multicase Study, Jacklyn Smith

Theses and Dissertations

This applied dissertation provided insight and identified impediments and obstacles in the areas of educational and societal assimilation, career and monetarist support, and academics to ascertain the effects they have on students transitioning from ESOL classes to EAP courses. Adult non-native speakers have evolved into an important segment of the adult population in the United States. Many Limited English Proficient (LEP) students lack the aptitude as it relates to the English language, often translating into lower wages, higher rates of poverty, and limited upward movement in the workplace. Researchers have identified several factors that may potentially influence the program participants …

Teachers’ Perceptions Of The Use Of Graphic Novels To Teach Reluctant Readers, Bret Ginsberg

Theses and Dissertations

The purpose of this qualitative study was to explore the perceptions of teachers in a suburban private school in Florida serving prekindergarten through Grade 8 regarding the use of graphic novels to increase student motivation to read. The problem was teachers were concerned with students’ inability to complete the required novels, demonstrate comprehension of deep meaning from the text, read silently, and read outside of school. Teachers raised serious concerns about the reading achievement of middle school students. Teachers also noted a frequent mismatch between the preference of the middle school reader and the instructional opportunities provided. The study was …

Hear My Voice And The Voices Of Those I Teach: A Phenomenological Perspective Of Experiences From Migrant Education Program Teachers, Ingrid Bynes

Theses and Dissertations

In the United States, there is an increasing need for educators to acknowledge and utilize culturally-relevant pedagogy within their classrooms. Many MEP educators in public schools, particularly those working in secondary education, find it challenging to ensure this disadvantaged and, often invisible, population is served in a consistent and productive manner. In fact, one indication highlighted in the literature is the lack of research on the perspective of educators in the secondary MEP classroom setting. Consequently, a study was conducted with this group of teachers to gain insight regarding their view of teaching Hispanic migrant students in a large rural …

Job Satisfaction, Organizational Stress And Use Of Force Attitudes Among Patrol Officers In North Carolina, Zachary James Lechette

Theses and Dissertations

This applied dissertation was designed to examine whether relationships existed between self-reported job satisfaction, organizational police stress and attitudes toward the use of force among urban non-supervisory local law enforcement patrol officers in North Carolina. A quantitative study of patrol officers (N = 137) from across North Carolina was conducted over a one-month period in the summer of 2018.

The researcher administered a combined survey instrument measuring job satisfaction, organizational police stress and use of force attitudes to local law enforcement patrol officers in North Carolina. The researcher administered the survey to participants at six different local law enforcement agencies …

Prevention Strategies To Reduce Multifactorial Risk Factors Associated With The Onset Of Coronary Artery Disease: A Systematic Review, Jacqueline A. Burnes

Theses and Dissertations

Noncommunicable diseases such as coronary artery disease continue to remain the principal cause of mortality in the United States, claiming nearly 800,000 lives in 2016. Reducing the onset of chronic diseases, specifically coronary artery disease, requires a fundamental approach to health care, involving patient access to high-quality primary care and accessibility to disease prevention programs. This study examined multifactorial risk factors and prevention mechanisms associated with coronary artery disease.

The applied dissertation is a systematic review of the literature designed to answer the question: What prevention strategies reduce multifactorial risk factors associated with the onset of coronary artery disease? The …

Evaluation Of A Climate Change Training Program For Local Government Employees, Clara Kashar

Theses and Dissertations

A local government in South Florida launched a training program to improve employee engagement on climate change using best practices in adult learning and climate communication to bridge the gap between climate science and action in government operations. The purpose of this program evaluation was to determine whether that climate change development and training program for local government employees met its stated goals and objectives. This evaluation blended a component of Stufflebeam’s Context, Input, Process, Product (CIPP) model with Kirpatrick’s Four Levels model. To conduct the evaluation, the researcher used a mixed methods approach for analyzing both quantitative and qualitative …

Latina Sorority Membership Impact On The Experience And Persistence Of Latinas In Higher Education, Luz Danela Randolph

Theses and Dissertations

Latinas face many challenges upon their matriculation to a university, including culture shock, acclimation and sense of belonging. Such challenges threaten their retention and success. Having support or a sense of belonging within higher education are notions that influence Latina students to continue or persist in school. An emphasized venue, which supports the educational journey of undergraduate Latinas, is involvement in organizations that reflect their culture. The problem addressed was the need to investigate how sorority involvement impacted their experience and persistence. Conducting research on Latina sorority membership and whether it has an impact on the experience and persistence of …

A Study Of In-School And Out-Of-School Life Experiences Affecting Veteran Teacher Retention In A Southeastern School District, Rosa Ana Jonson

Theses and Dissertations

The purpose of the research was to investigate the in-school and out-of-school life experiences affecting veteran teacher retention in a southeastern school district. The study sought to gain a better understanding of the factors that affected the decisions of teachers to remain with the district for more than 5 years. All of the teachers who had been working in the district for at least 5 years were potential research participant The survey was distributed to 75 teachers, and 24 teachers responded. The teachers were asked to respond to an online survey regarding their perceptions of their in-school and out-of-school experiences. …

Assessing Reading And Mathematics Achievement Of Students With Disabilities In A Suburban Middle School, Terri Melissa Toomer

Theses and Dissertations

Co-teaching classrooms consist of general and special education teachers working together to benefit students with disabilities (SWDs). Many parents and teachers believe the content knowledge provided by general educators in the regular education setting, combined with the instructional service delivery model (SDM) expertise of special educators, will result in the greatest academic growth for SWDs. However, it is not known if SWDs served in one SDM progress at a faster rate than SWDs served in another SWD. Therefore, the focus of this study was to compare the reading and mathematics achievement of male and female middle school SDWs in two …

To Participate Or Not To Participate In Education Research: A View From The Teacher’S Perspective, Jennifer Gans

Theses and Dissertations

This dissertation was designed to identify factors that might explain teacher resistance versus teacher support for participation in education research. To that end, predictor variables suggested by both diffusion of innovations theory, as well as personality trait theories were examined as unique predictors of variability in attitudes toward adoption of participation in the research process. Furthermore, “exposure to research” was examined as another possible variable that may be uniquely associated with willingness to participate in research, beyond the other theoretically motivated variables. The researcher developed a survey instrument featuring four research vignettes that increased in demands for teacher participation. Each …

The Effects Of An Afrocentric Curriculum On Reading Scores Of African American Third, Fourth, And Fifth Graders, Trisha J. Baker

Theses and Dissertations

The purpose of this applied research study was to determine the extent to which reading scores on the Diagnostic Reading Assessment (DRA-2) and Measures of Academic Progress (MAP) were impacted across the school years for students enrolled in Afrocentric curriculum (ACC) and non-ACC classrooms, excluding students enrolled in the two-way immersion classrooms, controlling for the test scores from the previous school year, during the 2012-2013, 2013-2014, 2014-2015, and 2015-2016 school years.

The research study followed a correlational research design to determine whether the size of the two reading-assessment scores varied across school years in efforts to determine whether the ACC …

Effectiveness And Impact Of The Sheltered Instruction Observational Protocol On Ell Student Academic Achievement, Gladymar Soto-Huertas

Theses and Dissertations

This applied dissertation was designed to determine the effectiveness of using the Sheltered Instruction Observation Protocol with fidelity for English Language Learners (ELL) and its impact on student academic achievement through FCAT Reading and FSA scores. In a high school located in Central Florida that served approximately 2,244 students there were 1,129 (50.6%) students classified as English Language Learners (ELLs), by the 2016-17 school year the school expected to have 62% of their entire student body passing state mandated assessments in order to make Adequate Yearly Progress (AYP) (PCSB, 2013).

In order for the aforementioned to take place it was …