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2018

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A Twenty-First-Century Olympic And Amateur Sports Act, Dionne L. Koller Jan 2018

A Twenty-First-Century Olympic And Amateur Sports Act, Dionne L. Koller

Vanderbilt Journal of Entertainment & Technology Law

Recent scandals involving national governing bodies for sport and allegations of athlete abuse have captured media attention. The most recent, focusing on the actions of USA Gymnastics, prompted Congress to propose legislation to require better protections for Olympic Movement athletes. Signed into law on February 14, 2018, the Protecting Young Victims from Sexual Abuse and Safe Sport Authorization Act of 2017 designates the United States Center for SafeSport (SafeSport) as the independent organization charged with exercising jurisdiction over the United States Olympic Committee (USOC) and sport national governing bodies to safeguard amateur athletes against all forms of abuse. Congress's instincts …


Biological Bases, Suzanne I. Sollars Jan 2018

Biological Bases, Suzanne I. Sollars

Psychology Faculty Publications

Lab Title: Structure/Function Relationships within Sensory Systems

Main Idea/Concept Demonstrated or Taught by Lab: Students will examine the way in which individual differences in anatomical structures can influence how the system functions. Perception of a sensory stimulus can vary between individuals. Such structure/function relations in physiological systems can change the way an individual behaves. In this lab, students will test taste intensity of salt and sugar solutions, quantify fungiform papillae (an indirect measure of the number of taste buds), and determine the correlation between the number of fungiform papillae and taste intensity ratings.

Lab Title: Modification of …


Serum Tumor Necrosis Factor-Alpha Associates With Myocardial Oxygen Demand And Exercise Tolerance In Postmenopausal Women, Stephen J. Carter, David R. Bryan, William H. Neumeier, Stephen P. Glasser, Gary R. Hunter Jan 2018

Serum Tumor Necrosis Factor-Alpha Associates With Myocardial Oxygen Demand And Exercise Tolerance In Postmenopausal Women, Stephen J. Carter, David R. Bryan, William H. Neumeier, Stephen P. Glasser, Gary R. Hunter

Internal Medicine Faculty Publications

The functional implications of serum tumor necrosis factor-alpha (TNF-α), a marker of oxidative stress, on hemodynamic parameters at rest and during physical exertion are unclear. The aims of this investigation were to examine the independent associations of TNF-α on myocardial oxygen demand at rest and during submaximal exercise, while also evaluating the association of TNF-α on exercise tolerance. Forty, postmenopausal women, provided blood samples and completed a modified-Balke protocol to measure maximal oxygen uptake (VO2max). Large artery compliance was measured by pulse contour analyses while rate-pressure product (RPP), an index of myocardial oxygen demand, was measured at rest …


Categorizing A Continuous Predictor Subject To Measurement Error, Betsabé G. Blas Achic, Tianying Wang, Ya Su, Victor Kipnis, Kevin Dodd, Raymond J. Carroll Jan 2018

Categorizing A Continuous Predictor Subject To Measurement Error, Betsabé G. Blas Achic, Tianying Wang, Ya Su, Victor Kipnis, Kevin Dodd, Raymond J. Carroll

Statistics Faculty Publications

Epidemiologists often categorize a continuous risk predictor, even when the true risk model is not a categorical one. Nonetheless, such categorization is thought to be more robust and interpretable, and thus their goal is to fit the categorical model and interpret the categorical parameters. We address the question: with measurement error and categorization, how can we do what epidemiologists want, namely to estimate the parameters of the categorical model that would have been estimated if the true predictor was observed? We develop a general methodology for such an analysis, and illustrate it in linear and logistic regression. Simulation studies are …


The Use Of Machine Learning To Detect Suckling In Pre-Weaned Calves, Sukumar Katamreddy Jan 2018

The Use Of Machine Learning To Detect Suckling In Pre-Weaned Calves, Sukumar Katamreddy

Theses

The weaning of cattle is a process which is known to be labour intensive and to have stressful effects on both cow and calf Common methods used in the weaning process include the temporary removal of a mother from the calf and manual observation and intervention. Early and speedy weaning is known to have a number of benefits, including health benefits for both cow and calf, additional weight gains for the calves as well as reduced labour and feed requirements. The process known as Two-Stage Weaning is recognised to be an effective low-stress approach to weaning in which the calf …


An Evaluation Of Trap-Neuter-Release Practices For Free-Roaming Cat Populations, Brian Gaston Jan 2018

An Evaluation Of Trap-Neuter-Release Practices For Free-Roaming Cat Populations, Brian Gaston

Master's Theses or Doctor of Nursing Practice

As of 2002, estimates of free-roaming domestic cat (Felis catus) populations exceeded 100 million individuals, throughout the United States. Many lost or abandoned cats will revert to living outdoors as free-roaming individuals. To try to control the abundance of free-roaming cats, trap-neuter-release (TNR) programs have been implemented across the United States. The goal of many TNR programs is to reduce cat populations by sterilizing the individuals to prevent breeding, while also providing food and water to the unconfined colony. However, wildlife conservationists question the effectiveness of TNR programs. The objectives of my study were to: determine the population size and …


Education Sector Interconnections: Foundation Level, Australian Council For Educational Research (Acer) Jan 2018

Education Sector Interconnections: Foundation Level, Australian Council For Educational Research (Acer)

Education Analytics Service

The purpose of this module is to provide an introduction to the key sub-sectors of education and the way they link and interconnect with each other. It provides a foundation to engage in this topic and apply advice from staff with operational or expert levels of knowledge in education. On successful completion you will be able to be an informed participant in forums related to education sector interconnections.


Education Pathways: Practitioner Level, Australian Council For Educational Research (Acer) Jan 2018

Education Pathways: Practitioner Level, Australian Council For Educational Research (Acer)

Education Analytics Service

This Practitioner level module is designed to ensure that all staff members who engage with and lead policy dialogue with international and domestic partners are informed about strategies to promote flexible, equitable and appropriate learning pathways and investment options to strengthen learning pathways. It is recommended that staff complete the Education Pathways: Foundation level module as background information to this Practitioner level module. Topics covered in this module cover: promoting flexible, equitable and appropriate learning pathways; the range of data that can be used to strengthen policy on education pathways; and how data can inform investment decisions.


Mobile Mindfulness: There's An App For That!, Katelyn Haschke Jan 2018

Mobile Mindfulness: There's An App For That!, Katelyn Haschke

Master's Theses or Doctor of Nursing Practice

Previous research indicates that practicing mindfulness-based strategies over an extended period of time may positively impact individuals’ well-being, such as improved mood and cognitive performance (Chambers, Lo, & Allen, 2008; Kabat-Zinn, 1990; Kabat-Zinn, 2003; Mrazek, Franklin, Phillips, Baird, & Schooler, 2013). This research also indicates there may be immediate benefits to practicing mindfulness strategies; however, a majority of the existing literature on this topic has focused primarily on extended mindfulness-practices over several weeks with an in-person guide or trained researcher. The purpose of the current study was two-fold. First, how practicing one of two mindfulness-based strategies for a short period …


The Missing Metric: An Evaluation Of Microorganism Importance In Wetland Assessments, Aaron John Onufrak Jan 2018

The Missing Metric: An Evaluation Of Microorganism Importance In Wetland Assessments, Aaron John Onufrak

Browse all Theses and Dissertations

In the contiguous US, an estimated 50% of original wetland areas have been lost since the late 1700s. In growing recognition of the importance of preserving wetland ecosystem function, federal and state agencies have developed proxy-based functional-assessment procedures to manage and preserve remaining wetland areas. Ohio uses the Ohio Rapid Assessment Method (ORAM) to score wetland quality based on six metrics: wetland size, buffer width and surrounding land use, hydrology, habitat alteration and development, special wetland communities, and vegetation. Currently, the ORAM, and many other wetland scoring systems, do not consider microorganisms when determining wetland quality. This is particularly notable, …


Experimentally Investigating The Joint Effects Of Physical Activity And Sedentary Behavior On Depression: A Randomized Controlled Trial, Jeremiah Blough Jan 2018

Experimentally Investigating The Joint Effects Of Physical Activity And Sedentary Behavior On Depression: A Randomized Controlled Trial, Jeremiah Blough

Electronic Theses and Dissertations

Objective: To experimentally examine whether increasing sedentary behavior, among a young adult active population, for one week is still associated with increased depression symptomology even when allowing for a moderate engagement in physical activity (PA). Methods: Participants were confirmed as active via self-report and accelerometry during baseline and randomly assigned to one of three experimental groups. The Sedentary Intervention Group (n=19) reduced steps to less than 5000/day and were not alloto exercise for one-week; the Reduced MVPA (moderate-to-vigorous PA) Group (n=18) reduced steps to less than 5000/day but exercised for 50% of their previously reported vigorous PA for one-week; and …


Home Is Where The Hot Tamale Is: Rediscovering The Delta, Georgia Corinne Clarke Jan 2018

Home Is Where The Hot Tamale Is: Rediscovering The Delta, Georgia Corinne Clarke

Electronic Theses and Dissertations

This thesis project is an in-depth personal exploration of the hot tamale in the Mississippi Delta, presented in a long-form magazine piece. It analyzes the cultural exchange that brought the hot tamale to the region in the early 20th century, its racial representation in the Delta, and its future as chefs across the nation seek to interpret the regional cuisine. Further, this thesis analyzes the hot tamale’s components that tell why and how the hot tamale became a staple, and the story of hardship and discrimination that it symbolizes. Traveling through my own past, this piece reflects the interactions that …


A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu Jan 2018

A Novel Acetaminophen Soft-Chew Formulation Produced Via Hot Melt Extrusion With Inline Near-Infrared Monitoring As A Process Analytical Technology Tool, Pengchong Xu

Electronic Theses and Dissertations

People suffer dysphagia when swallowing hard tablets and capsules. Gelatin based soft chewable tablets was used as an alternative and novel drug delivery format to overcome dysphagia. But conventional method of producing gelatin based soft chewable tablets has many potential issues. The objective of this study is using glycerol and hot-melt extrusion technique to address potential issues and optimizing the formulation. Gelatin (15%), acetaminophen (30%), saccharin (1.5%), xylitol (6.5%), sodium chloride (2%) and six different ratios of water (45-0%) and glycerol (0-45%) were used in seven formulations. The extrusion process temperature of formulation 1-6 and formulation 7 were 90 ëšc …


Response To Professor Farber’S “Regulatory Review In Anti-Regulatory Times”, Richard J. Pierce Jr Jan 2018

Response To Professor Farber’S “Regulatory Review In Anti-Regulatory Times”, Richard J. Pierce Jr

GW Law Faculty Publications & Other Works

This is a response to an article by Professor Dan Farber presented in a symposium about the Trump Administration and Administrative Law at Chicago-Kent School of Law. After agreeing with Professor Farber’s description, analysis and critique of the Trump Administration’s use and abuse of cost benefit analysis as an aid in making regulatory decisions, Professor Pierce makes four points: (1) President Trump will fail to implement his deregulatory agenda; (2) EPA’s proposed rule on transparency of scientific evidence is a good start on an important project; (3) the Clean Power Plan is a lost cause; and, (4) The Trump Administration …


Evaluation Of Barriers For Small-Scale Fruit And Vegetable Growers In Kentucky, Amanda Schroeder Hege Jan 2018

Evaluation Of Barriers For Small-Scale Fruit And Vegetable Growers In Kentucky, Amanda Schroeder Hege

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The food system in the United States has witnessed significant challenges resulting in food security and safety concerns, environmental damage, economic distress, and a decline in our population’s health. While the last fifty years showed a drop in land and workforce dedicated to farming, industrialized farms are producing an overabundance of cheap corn that directly supplies inexpensive, unhealthy foods leading to American’s diets falling short of recommendations for good health, thus contributing to the obesity epidemic. This study utilizes an upstream approach to learn from farmers’ ability to grow good food that promotes healthy people, environments, and communities. Specifically, the …


The Relationship Between Access To Healthcare And Heart Disease Mortality In Kentucky, 2012-2014, Nima Farsi Jan 2018

The Relationship Between Access To Healthcare And Heart Disease Mortality In Kentucky, 2012-2014, Nima Farsi

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Cardiovascular disease is the cause for a large portion of the mortalities in the United States. Furthermore, Kentucky has one of the highest heart disease mortality rates out of all 50 U.S. States. This study hypothesized that heart disease mortality in Kentucky counties has a positive relationship with lack of accessibility to healthcare. Furthermore, this ecological study hypothesized that because there is no available usual source of a healthcare providers and ultimately a lack of accessibility to receive diagnostic/preventative services for this population, the high rate of cardiovascular disease mortality in Kentucky is dependent on access to healthcare services.

This …


Implementing The National Diabetes Prevention Program In Mason County, Kentucky, Cassandra Yelton Jan 2018

Implementing The National Diabetes Prevention Program In Mason County, Kentucky, Cassandra Yelton

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The National Diabetes Prevention Program (DPP) is sponsored by the Centers for Disease Control and Prevention (CDC). The program’s goal is to reduce the incidence of diabetes through dietary modification and physical activity. On one hand, the DPP is currently offered by various organizations through the country. On the other hand, the DPP is mostly unavailable in rural areas, especially the Diabetes Belt. The Diabetes Belt is in the eastern Appalachian region of the United States. People who live in this area of the country are more likely to develop diabetes than those who do not. Mason County, Kentucky has …


Microclinic International Social Network Behavioral Health Intervention In Mongolia, Kalli A. Beasley Jan 2018

Microclinic International Social Network Behavioral Health Intervention In Mongolia, Kalli A. Beasley

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Diabetes is a chronic communicable disease that is projected by 2030 to be the seventh leading cause of death worldwide. In Mongolia diabetes and cardiovascular disease are the number one reason for disability-adjusted life years and trends of diabetes is starting to be observed in the poorer populations. Diabetes in countries like Mongolia are extremely costly to treat using insulin, costing $200 USD per month while the average annual income sits only at $1,466.85 USD. Mongolia has a total population of 2,959,000 and half of its population resides in the capital city of Ulaanbaatar. 60% of residents in capital live …


Using A Video Modeling-Based Intervention Package To Teach Hand Washing To Children With Autism, Ndaru Prapti Jan 2018

Using A Video Modeling-Based Intervention Package To Teach Hand Washing To Children With Autism, Ndaru Prapti

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The purpose of this study was to teach four preschool children with autism spectrum disorder (ASD) to wash their hands independently using a video modeling-based intervention package. A research questions was asked: Is there a functional relation between a video modeling-based intervention package and increases in level and trend for washing hands independently? A multiple probe across participants design was used to answer this question. Results indicated that the intervention package had functional relation with the increase in level and trend of the three participants’ performance in washing hands. The intervention package of video modeling and least-to-most prompting was found …


Influence Of Dietary Ractopamine And Supranutritional Supplementation Of Vitamin E On Proteome Profile Of Postmortem Beef Longissimus Lumborum Muscle, Hyun Mok Kim Jan 2018

Influence Of Dietary Ractopamine And Supranutritional Supplementation Of Vitamin E On Proteome Profile Of Postmortem Beef Longissimus Lumborum Muscle, Hyun Mok Kim

Theses and Dissertations--Animal and Food Sciences

The effects of dietary ingredients on the proteome profile of postmortem beef longissimus lumborum (LL) muscle were evaluated. In the first experiment, the influence of dietary ractopamine on the whole-muscle proteome of beef LL was examined. Five proteins were differentially abundant between ractopamine-fed (RAC) and non-ractopamine fed (CON) groups. The differentially abundant proteins were over-abundant in RAC and were related to muscle structure development (F-actin-capping protein subunit beta-2 and PDZ and LIM domain protein-3), chaperone (heat shock protein beta-1), oxygen transportation (myoglobin), and glycolysis (L-lactate dehydrogenase A chain). These findings indicated that ractopamine influences the abundance of proteins associated with …


Comparing Dairy Farm Performance And Heat Stress Abatment Strategies In The United States Using Summer To Winter Ratios, Jenna M. Guinn Jan 2018

Comparing Dairy Farm Performance And Heat Stress Abatment Strategies In The United States Using Summer To Winter Ratios, Jenna M. Guinn

Theses and Dissertations--Animal and Food Sciences

Heat stress abatement is a challenge for producers in the United States, especially in the southern states. Dairy producers could benefit by having a simply metric to measure heat stress abatement strategies with the goal of motivating improvement in heat stress management. Managing heat stress is key to ameliorating the effects on dairy cow performance. A study was performed to explore the use of a heat stress metric called the Summer to Winter performance ratio (S:W ratio), to quantify and compare farm performance variables among regions of the United States. Summer to Winter ratios were closest to 1.0 in the …


Long-Term Effects Of Dietary Copper Source And Level On Performance And Health Of Sows And Piglets, Ning Lu Jan 2018

Long-Term Effects Of Dietary Copper Source And Level On Performance And Health Of Sows And Piglets, Ning Lu

Theses and Dissertations--Animal and Food Sciences

The objectives of this study were to investigate the long-term effects of feeding increasing supplemental levels (20, 120, or 220 mg/kg) of dietary copper (Cu) as tribasic copper chloride (TBCC) or copper sulfate (CuSO4) on performance, antioxidant status, nutrient digestibility, and trace mineral deposition of sows and piglets; as well as to assess nursery dietary Cu levels on growth performance and response to immunological challenge in nursery pigs from sows fed either high or low Cu diets. In the long-term sow experiment, sows fed TBCC diets had greater adjusted weaning weight for litter and piglet (P < 0.10), as well as adjusted litter and piglet weight gain (P …


Applications In Utilization Of Forage Chemical Composition And Predicting Equine Digestibility, Veronica Taylor Bill Jan 2018

Applications In Utilization Of Forage Chemical Composition And Predicting Equine Digestibility, Veronica Taylor Bill

Theses and Dissertations--Animal and Food Sciences

Most forage quality models were developed for ruminant nutrition, and may not apply to the horse. This two-part study evaluated the relationship between forage chemical composition and dry matter digestibility (DMD) using an in vitro method with equine feces as the inoculums. The first experiment determined that compared to 48 h of incubation, 72 h of incubation resulted in higher DMD for some forages. As a result of experiment 1, incubations in experiment 2 were conducted using 48 and 72 h incubation periods at 38 degrees C. The second experiment evaluated the effect of chemical composition on DMD. Thirty-one hay …


Effect Of Exogenous Enzymes On Apparent Metabolizable Energy Value Of Barley In Swine And Broiler Chickens, Brian L. Bryson Jan 2018

Effect Of Exogenous Enzymes On Apparent Metabolizable Energy Value Of Barley In Swine And Broiler Chickens, Brian L. Bryson

Theses and Dissertations--Animal and Food Sciences

The objective of this thesis was to evaluate the effect of exogenous enzyme supplementation, phytase and xylanase-glucanase, on AME value of barley in poultry and swine. In the first study, 280 broilers were assigned 1 of 8 treatments. Barley inclusion in the diet resulted in decreased (P < 0.05) performance. There was a treatment × phytase × xylanase-glucanase interaction for dry matter retention with birds fed the corn-SBM-barley diet supplemented with phytase and xylanase-glucanase having higher (P < 0.05) DM retention compared to birds fed corn-SBM-based diet with only xylanase-glucanase supplementation. AME and AMEn of corn-SBM-based diets were greater (P < 0.05) than the corn-SBM-barley-based diets. Energy metabolizability and AMEn of barley significantly increased with xylanase-glucanase supplementation. In the second study, 24 pigs (12 pigs/phase) were assigned to 1 of 4 treatments with xylanase-glucanase and phytase. After a 7-d adaption period, urine and feces were quantitatively collected for 5 d. DE of the barley-based diet supplemented with xylanase-glucanase (3,578 kcal/kg) and phytase and xylanase-glucanase in combination (3,617 kcal/kg) were significantly different. Compared to control diets, exogenous enzymes either significantly improved or had a tendency to improve AME and AMEn value of barley in broilers, but not in growing pigs.


Compost Bedded Pack Dairy Housing: Animal Performance And Well-Being And Economic Viability In A Pasture-Based System, Betty Kawonga Jan 2018

Compost Bedded Pack Dairy Housing: Animal Performance And Well-Being And Economic Viability In A Pasture-Based System, Betty Kawonga

Theses and Dissertations--Animal and Food Sciences

Improving housing for dairy cattle is of interest because hoof and udder health, which are associated with the housing environment, are important economic and welfare issues. The objectives were: 1) to assess the influence of housing––conventional cubicle (CCD) vs compost bedded pack (CBP),––and management (grazing vs semi-grazing) on the performance and welfare in dairy cows 2) describe the performance of the CBP under a grazing or semi-grazing system, and 3) to assess viability of CBP housing in a pasture-based system. This study mixes three research approaches, an analysis of existing and secondary data; an experiment, and a case-study. If taken …


Unending Mazes: Gendered Inequalities, Drug Use, And State Interventions In Rural Appalachia, Lesly-Marie Buer Jan 2018

Unending Mazes: Gendered Inequalities, Drug Use, And State Interventions In Rural Appalachia, Lesly-Marie Buer

Theses and Dissertations--Anthropology

Prescription opioids are associated with rising rates of overdose deaths and hepatitis C and HIV infection in the US, including in rural Central Appalachia. Yet there is a dearth of published ethnographic research examining rural opioid use. The aim of this dissertation is to document the gendered inequalities that situate women’s encounters with substance abuse treatment as well as additional state interventions targeted at women who use drugs. These results are based on ethnographic fieldwork completed from 2013 to 2016 and centered around one county seat in rural Central Appalachia. Data are ascertained through semi-structured interviews with women who have …


Evaluating The Relationship Between Physician Characteristics And Opioid Knowledge And Use Of Opioid And Non-Opioid Chronic Pain Management Strategies, Erin Hopkins Stern Jan 2018

Evaluating The Relationship Between Physician Characteristics And Opioid Knowledge And Use Of Opioid And Non-Opioid Chronic Pain Management Strategies, Erin Hopkins Stern

PCOM Psychology Dissertations

Opioid use disorder (OUD) is a mental health condition that has high personal, societal, and emotional costs. Opioid use disorder, misuse, and abuse is a national epidemic. Many factors have contributed to the increased use of opioids and OUD. One such factor is the heightened emphasis on pain management in the medical community, one that that began nearly two decades ago. This has led to increased prescribing of opioid-based medication for chronic pain patients. This contributed in part to the development of OUD in many individuals who became addicted to opioids. For this reason, current guidelines discourage the use of …


Association Between Acculturation And Body Weight Status Among Migrant Children In Guangzhou, China: A Cross-Sectional Study, Xiaoling Huang, Wen Chen, Yanwei Lin, Qi Zhang, Li Ling Jan 2018

Association Between Acculturation And Body Weight Status Among Migrant Children In Guangzhou, China: A Cross-Sectional Study, Xiaoling Huang, Wen Chen, Yanwei Lin, Qi Zhang, Li Ling

Community & Environmental Health Faculty Publications

Objective To assess the association between acculturation and body weight status among internal migrant children in China. Design, setting and participants A cross-sectional study was conducted among 1154 pairs of migrant children aged 11–17 years and their primary caregivers in Guangzhou, China, from April to May 2016. Measures Migrant children’s body weight status was measured by body mass index. Acculturation was measured by a questionnaire, developed and validated by the research team. The questionnaire had three dimensions with five factors, namely language, social interaction, custom, dressing and diet. Social anxiety was measured by Social Anxiety Scale for Children. Food intake …


Effects And Moderators Of Psychosocial Interventions On Quality Of Life, And Emotional And Social Function In Patients With Cancer: An Individual Patient Data Meta‐Analysis Of 22 Rcts, J. Kalter, I. M. Verdonck-De Leeuw, M. G. Sweegers, N. K. Aaronson, P. B. Jacobsen, Robert U. Newton, K. S. Courneya, J. F. Aitken, J. Armes, C. Arving, L. J. Boersma, A. M.J. Braamse, Y. Brandberg, S. K. Chambers, J. Dekker, K. Ell, R. J. Ferguson, M. F. M. Gielissen, B. Glimelius, M. M. Goedendorp, K. D. Graves, S. P. Heiney, R. Horne, M. S. Hunter, B. Johansson, M. L. Kimman, H. Knoop, K. Meneses, L. L. Northouse, H. S. Oldenburg, J. B. Prins, J. Savard, M. Van Beurden, S. W. Van Den Berg, J. Brug, Laurien M. Buffart Jan 2018

Effects And Moderators Of Psychosocial Interventions On Quality Of Life, And Emotional And Social Function In Patients With Cancer: An Individual Patient Data Meta‐Analysis Of 22 Rcts, J. Kalter, I. M. Verdonck-De Leeuw, M. G. Sweegers, N. K. Aaronson, P. B. Jacobsen, Robert U. Newton, K. S. Courneya, J. F. Aitken, J. Armes, C. Arving, L. J. Boersma, A. M.J. Braamse, Y. Brandberg, S. K. Chambers, J. Dekker, K. Ell, R. J. Ferguson, M. F. M. Gielissen, B. Glimelius, M. M. Goedendorp, K. D. Graves, S. P. Heiney, R. Horne, M. S. Hunter, B. Johansson, M. L. Kimman, H. Knoop, K. Meneses, L. L. Northouse, H. S. Oldenburg, J. B. Prins, J. Savard, M. Van Beurden, S. W. Van Den Berg, J. Brug, Laurien M. Buffart

Research outputs 2014 to 2021

Objective

This individual patient data (IPD) meta‐analysis aimed to evaluate the effects of psychosocial interventions (PSI) on quality of life (QoL), emotional function (EF), and social function (SF) in patients with cancer, and to study moderator effects of demographic, clinical, personal, and intervention‐related characteristics.

Methods

Relevant studies were identified via literature searches in 4 databases. We pooled IPD from 22 (n = 4217) of 61 eligible randomized controlled trials. Linear mixed‐effect model analyses were used to study intervention effects on the post‐intervention values of QoL, EF, and SF (z‐scores), adjusting for baseline values, age, and cancer type. We studied …


Associations Of Four Community Factors With Longitudinal Change In Hemoglobin A1c Levels In Patients With Type 2 Diabetes, Elizabeth Durden Jan 2018

Associations Of Four Community Factors With Longitudinal Change In Hemoglobin A1c Levels In Patients With Type 2 Diabetes, Elizabeth Durden

Faculty Journal Articles

OBJECTIVE

To evaluate associations of community factors with glycated hemoglobin (HbA1c).

RESEARCH DESIGN AND METHODS

We identified patients with type 2 diabetes who had an HbA1c ‡7.5% (58 mmol/mol) and subsequent HbA1c testing within 90–270 days. We used mixed-effect models to assess whether treatment intensification (TI) and community domains (community socioeconomic deprivation [CSD], food availability, fitness assets, and utilitarian physical activity favorability [quartiled]) were associated with HbA1c change over 6 and 24 months, controlling for demographics, HbA1c, BMI, and time with evidence of type 2 diabetes. We evaluated whether community domains modified associa- tions of TI with HbA1c change using …