Digital Commons Network^™

Mechanical Suppression Of Osteolytic Bone Metastases In Advanced Breast Cancer Patients: A Randomised Controlled Study Protocol Evaluating Safety, Feasibility And Preliminary Efficacy Of Exercise As A Targeted Medicine, Nicolas H. Hart, Daniel A. Galvão, Christobel Saunders, Dennis R. Taaffe, Kynan T. Feeney, Nigel A. Spry, Daphne Tsoi, Hilary Martin, Raphael Chee, Tim Clay, Andrew D. Redfern, Robert U. Newton

Research outputs 2014 to 2021

BACKGROUND: Skeletal metastases present a major challenge for clinicians, representing an advanced and typically incurable stage of cancer. Bone is also the most common location for metastatic breast carcinoma, with skeletal lesions identified in over 80% of patients with advanced breast cancer. Preclinical models have demonstrated the ability of mechanical stimulation to suppress tumour formation and promote skeletal preservation at bone sites with osteolytic lesions, generating modulatory interference of tumour-driven bone remodelling. Preclinical studies have also demonstrated anti-cancer effects through exercise by minimising tumour hypoxia, normalising tumour vasculature and increasing tumoural blood perfusion. This study proposes to explore the promising …

Does Persistent Snowpack Inhibit Degradation Of Fecal Stress Indicators?, Grace Parikh, Christopher R. Webster, John A. Vucetich, John J. Durocher, Joseph K. Bump

Michigan Tech Publications, Part 1

Physiological stress in wildlife can be a useful indicator of a population’s response to environmental factors. By using non-invasive endocrinological techniques, such as fecal sampling, potential confounding factors associated with the stress of capture can be avoided. A potential drawback of fecal sampling, however, is degradation of samples which may produce aberrant measurements of fecal glucocorticoid metabolites. In vertebrates, glucocorticoids, such as corticosterone, become elevated in response to stress. We sought to gauge the reliability of measurement of fecal glucocorticoid metabolites from white-tailed deer (Odocoileus virginianus) fecal samples exposed to a temperate winter with substantial snow cover and …

The Alignment Of Esl Materials To Wida And State Standards, Jenna Marie Quanbeck

Dissertations, Theses, and Projects

This project analyzed the various 2^nd grade English language (EL) materials that were available in a rural elementary school to determine how those materials aligned to Minnesota (MN) state academic standards and the WIDA English Language Development standards. First, the various bodies of literature available on alignment and current recommendations for determining alignment between course content and state academic standards were reviewed. Then, the researcher developed and implemented a checklist-based process for determining alignment. This paper presents the literature review, the checklists, and the results of the analysis. The materials were found to be aligned to standards. The researcher …

Life In Balance: The Work-Life Balance Stories Of Black Female School Leaders, Jaime Mecholle Johnson

LSU New Orleans Theses and Dissertations

The purpose of this study is to examine the work-life balance experiences of Black females school leaders. Due to the inherent intersectionality of race and gender that is experienced by Black females, a study of their unique experiences with work-life balance is valuable to the field of educational leadership. The responsibilities associated with school leadership positions are extensive and those school leaders who also have spouses and children must figure out a way to fulfill responsibilities associated with each role. Work-life balance is important to understand for school leaders whose career responsibilities may interact with those associated with their personal …

Seeing Red: Immigration And Asymmetrical Partisan Polarization In The United States, Robert M. Worth

LSU New Orleans Theses and Dissertations

Since the mid-1970s, partisan polarization has been increasing in Congress and the Presidency, and, although most voters lack a stable, consistent ideology, non-ideological forms of partisan polarization have emerged in the mass public in recent decades. Moreover, ideological polarization among elites is highly asymmetrical, with increased Republican conservatism accounting for most of the increased ideological distance between the parties. Here, I develop a racial-threat backlash theory and argue that increased rates of immigration are associated with increased asymmetrical ideological polarization among elites and in the mass public. Tests of this theory on voters, the mass public in the states, state …

Dynamic Response Of A Hingeless Helicopter Rotor Blade At Hovering And Forward Flights, Pratik Sarker

LSU New Orleans Theses and Dissertations

The helicopter possesses the unrivaled capacity for vertical takeoff and landing which has made the helicopter suitable for numerous tasks such as carrying passengers and equipment, providing air medical services, firefighting, and other military and civil tasks. The nature of the aerodynamic environment surrounding the helicopter gives rise to a significant amount of vibration to its whole body. Among different sources of vibrations, the main rotor blade is the major contributor. The dynamic characteristics of the hingeless rotor consisting of elastic blades are of particular interest because of the strongly coupled equations of motion. The elastic rotor blades are subjected …

Impact Of Labor Protection Laws On The Operating And Financial Risks Of Firms: The Case Of China, Yuxin Huang

LSU New Orleans Theses and Dissertations

A debate exists regarding the effect of labor protection laws on labor costs. Whether labor protection laws increase or decrease labor costs has implications for risk exposure of affected firms. If the labor costs go up, all else the same, the firm’s breakeven point goes up. Facing increased business risk, the firm must resort to strategies that inhibit the risk exposure, especially if the higher labor costs cannot be transferred, without adverse consequences, to consumers. The strategies include reigning in, if at all possible, operating leverage and financial leverage. Conversely, if the labor costs decrease, a firm’s business risk declines, …

Creating The Water Clock, Amy C. Laws

LSU New Orleans Theses and Dissertations

This thesis will discuss the making of my short film The Water Clock at the University of New Orleans from its inception to its final short film form. Part One discusses the balancing of content and style and explores the relation between time and water as inspirations for story. Part Two details the preproduction process and major crew members’ collaborations and contributions before filming. Part Three describes daily successes, struggles, and direction while in production. Part Four describes every phase of the post-production process as the film is completed. Lastly, I will analyze my personal growth as a filmmaker.

Innovation, Ownership And Ipo Underpricing, Roman Bohdan

LSU New Orleans Theses and Dissertations

This dissertation consists of two empirical essays. The first chapter titled: “Hedge Fund Activism and Dual Ownership of U.S. Multinationals”. Harford, Wang & Zhang (2017) conclude that holding high cash balances abroad to avoid US taxes causes internal capital markets and investments distortions. We posit that hedge funds target MNCs with more severe internal capital and agency problems. We demonstrate that upon acquiring dual ownership in these firms, hedge funds reduce internal capital problems and improve investment, especially innovation, efficiencies. To further reduce agency costs of foreign cash holdings, hedge funds engage dual firms in focused acquisitions. These improvements are …

Feasible Form Parameter Design Of Complex Ship Hull Form Geometry, Thomas L. Mcculloch

LSU New Orleans Theses and Dissertations

This thesis introduces a new methodology for robust form parameter design of complex hull form geometry via constraint programming, automatic differentiation, interval arithmetic, and truncated hierarchical B- splines. To date, there has been no clearly stated methodology for assuring consistency of general (equality and inequality) constraints across an entire geometric form parameter ship hull design space. In contrast, the method to be given here can be used to produce guaranteed narrowing of the design space, such that infeasible portions are eliminated. Furthermore, we can guarantee that any set of form parameters generated by our method will be self consistent. It …

Shaking The Frame: Graduates' Perceptions Of A School Leadership Program With A Social Justice Focus, Cherie H. Goins

LSU New Orleans Theses and Dissertations

Abstract

Educational leaders who have an awareness of social justice are those who advocate for and achieve more equitable schools. School leader preparation programs that focus on social justice may help to improve schools, systems, and society (Dentith & Peterlin, 2011; Boske, 2012; Marshall and Oliva, 2006; Shields, 2004, 2010, 2012). For the purpose of this study, social justice is defined as fairness in terms of distribution of wealth, social privileges and opportunities within society. Some school leaders experience transformative processes which increase their critical awareness or consciousness during their formal preparation.

What is not known is the extent to …

Assessment Of Two Pedagogical Tools For Cybersecurity Education, Pranita Deshpande

LSU New Orleans Theses and Dissertations

Cybersecurity is an important strategic areas of computer science, and a difficult discipline to teach effectively. To enhance and provide effective teaching and meaningful learning, we develop and assess two pedagogical tools: Peer instruction, and Concept Maps. Peer instruction teaching methodology has shown promising results in core computer science courses by reducing failure rates and improving student retention in computer science major. Concept maps are well-known technique for improving student-learning experience in class. This thesis document presents the results of implementing and evaluating the peer instruction in a semester-long cybersecurity course, i.e., introduction to computer security. Development and evaluation of …

Automating The Detection Of Precipitation And Wind Characteristics In Navy Ocean Acoustic Data, Joseph T. Kuhner

LSU New Orleans Theses and Dissertations

A challenge in Underwater Acoustics is identifying the independent variables associated with an environment’s ambient noise. A strict definition of ambient noise would focus on non-transient signatures and exclude transient impacts from marine mammals, pelagic fish species, man-made sources, or weather events such as precipitation or wind speeds. Recognizing transient signatures in acoustic spectra is an essential element for providing environmental intelligence to the U.S. Navy, specifically the acoustic signatures from meteorological events. While weather event detection in acoustic spectra has been shown in previous studies, leveraging these concepts via U.S. Navy assets is largely an unknown. Environmental intelligence collection …

Laboratory Evaluation Of Recycled Crushed Glass Cullet For Use As An Aggregate In Beach Nourishment And Marsh Creation Projects In Southeastern Louisiana, John C. Wildman

LSU New Orleans Theses and Dissertations

To combat the rapid degradation of the Louisiana coast, the Louisiana Coastal Protection and Restoration Authority has planned strategic land building initiatives throughout the Louisiana Gulf coast, including beach nourishment and marsh creation projects. It is commonly agreed that the state lacks sufficient renewable sediment resources to maintain the planned CPRA land building program. However, Louisiana, the state that commonly ranks last in state recycling percentage, recycles an estimated 0.6% of the waste glass consumed in the state. Glass is predominantly silica sand. This thesis evaluates laboratory‑determined characteristics of recycled crushed glass cullet to assess its suitability as a renewable …

Numerical Simulation Of Dropped Cylindrical Objects Into Water In Two Dimensions (2d), Yi Zhen

LSU New Orleans Theses and Dissertations

The dropped objects are identified as one of the top ten causes of fatalities and serious injuries in the oil and gas industry. It is of importance to understand dynamics of dropped objects under water in order to accurately predict the motion of dropped objects and protect the underwater structures and facilities from being damaged. In this thesis, we study nondimensionalization of dynamic equations of dropped cylindrical objects. Nondimensionalization helps to reduce the number of free parameters, identify the relative size of effects of parameters, and gain a deeper insight of the essential nature of dynamics of dropped cylindrical objects …

Vocabulary Needs For The General Education Curriculum At A Four-Year University In The U.S., Esraa Kadhem

Dissertations, Theses, and Projects

The purpose of this study sought to find out the key terms and concepts needed for international students to succeed in the general education courses in a four-year university in the United States. This study analyzed existing enrollment data across three academic year (2014-2015, 2015-2016, and 2016-2017) to learn which general education course is most frequently taken by international students. One course in each LASC area was identified as the top one from the most frequent taken courses by international students. After identifying the top ten courses, answers on vocabulary needs were obtained by conducting semi-structured interviews with permanent faculty …

The Important Role Of The Faculty Advisor In Credit-Bearing Internship Opportunities, Allison Goossens

Dissertations, Theses, and Projects

Much of the research that surrounds internships and other student experiential learning focuses on the student and the inherent benefits that they reap from such experiences. Much of this research is viewed through a developmental lens, examining how students benefit and in what conditions are conducive to the learning taking place. What is not widely noted is the work that the faculty advisors do to help facilitate that learning, ensuring that the experience is held to a high level of academic integrity. Here, the literature around this topic is explored and the importance of the faculty advisor and the role …

Creating An Adult Learner Entry Achievement Program, Gloria Riopelle

Dissertations, Theses, and Projects

ABSTRACT

This proposal is to implement an Adult Learner Entry Achievement Program (ALEAP) within higher education institutions. The purpose of the ALEAP program is to support and serve the needs of adult learners who want to return to or begin college to earn their degree or certificate and pursue their personal or career goals. In turn, their achievements will also increase the higher education attainment rates in the State of Minnesota. This program could exist as a stand-alone program or be housed within support systems, such as, Continuing Education or an Academic Support Center.

Current research indicates that there is …

Using Small Group Reading Instruction To Improve Reading Fluency In First Grade, Michaela Kolness

Dissertations, Theses, and Projects

This paper explores the effect of teaching evidence-based fluency strategies in a small group setting to improve first grade students’ reading fluency. Students for this study were chosen based on an aimswebPlus fluency assessment. Students that scored below grade level in the area of reading fluency were chosen to participate. Four of these students were put into a small reading group. They received targeted fluency instruction twenty minutes a day, four days a week for five weeks. The fluency instruction they receive included practice with reading high frequency words, poetry practice, repeated readings, decoding practice and read alouds. The remaining …

A Single Subject Design Study; Utilizing Visual Schedules To Reduce Behaviors During Hallway Transitions, Nicole Amber Degner

Dissertations, Theses, and Projects

Abstract This study examined whether a Visual Activity Schedule would aid in reduction of disruptive behaviors during hallway transitions. Subject of this study was a six-year-old, Caucasian male, diagnosed with Oppositional Defiant Disorder. The study used a single-subject experimental design to determine baseline, intervention phase and removal of intervention phase. Specifically, the study revealed intervention strategies of a Visual Schedule was associated with 100% reduction of disruptive behaviors. Relationship development between paraprofessional and Student was found to be a secondary factor.

Verizon Wireless Communications: A Financial Analysis, Mackenzie Barry

Dissertations, Theses, and Projects

Verizon Communications, Inc. (VZ) operates the largest wireless and second largest wireline telecom networks in the United States. These two segments focus on providing communication, information, and entertainment to consumers, businesses, and government agencies. Verizon is based out of New York, New York and was incorporated in 2000.

Through both, qualitative and quantitative analysis, this report contains detailed information regarding the industry in which Verizon Communications competes, the market and sector it functions through, and the current growth structure it holds. A detailed valuation model from historical data, market statistics, and pro forma forecasts is attached. From this valuation model, …

The Role Of An Advanced Practice Provider (App) And Its Relation To Physician Shortages And Rural Healthcare Survival: A State-By-State Analysis, Allen Anderson

Dissertations, Theses, and Projects

The extent that Advanced Practice Providers (APPs) are able to practice independently with a full scope of practice varies state-by-state. The purpose of this paper was to review how APPs could help in a number of different areas of healthcare. This analysis examines the state of rural healthcare and reviews physician shortage statistics and hospital closures by state. In the examination, it also evaluates which states have full scope, reduced scope, and restricted scope of practice laws and cross-references that with states that have experienced a hospital closure. Through case studies, this research finds that APPs can be an alternative …

Aicpa Code Of Professional Conduct, Effective December 15, 2014. Updated For All Official Releases Through September 1, 2018, American Institute Of Certified Public Accountants (Aicpa)

AICPA Professional Standards

No abstract provided.

Fine-Grained Topic Models Using Anchor Words, Jeffrey A. Lund

Theses and Dissertations

Topic modeling is an effective tool for analyzing the thematic content of large collections of text. However, traditional probabilistic topic modeling is limited to a small number of topics (typically no more than hundreds). We introduce fine-grained topic models, which have large numbers of nuanced and specific topics. We demonstrate that fine-grained topic models enable use cases not currently possible with current topic modeling techniques, including an automatic cross-referencing task in which short passages of text are linked to other topically related passages. We do so by leveraging anchor methods, a recent class of topic model based on non-negative matrix …

The Role Of Resilience Among K-12 Principals And Administrators Leading Transformational Change, Paige Evans Wescott

Education Dissertations

Abstract

The United States government holds high expectations for principals and administrators, as they are responsible for enacting significant change to actualize school improvement and meet national agendas. Schools have specific characteristics that make change extremely challenging to implement, and it is within this context that fostering resilience holds promise. This study was a quantitative, correlational study that looked critically at the relationship between self-perceived resilience and self-perceived transformational leadership among US principals and administrators in K-12 settings. Peer-reviewed research studies addressing resilience and transformational leadership in K-12 education have been minimal, although similar questions in research continue to be …

Resveratrol Attenuates Allergic Asthma And Associated Inflammation In The Lungs Through Regulation Of Mirna-34a That Targets Foxp3 In Mice, Esraah Alharris, Hasan Alghetaa, Ratanesh K. Seth, Saurabh Chatterjee, Narendra P. Singh, Mitzi Nagarkatti, Prakash Nagarkatti

Faculty Publications

Asthma is a chronic inflammatory disease of airways mediated by T-helper 2 (Th2) cells involving complex signaling pathways. Although resveratrol has previously been shown to attenuate allergic asthma, the role of miRNA in this process has not been studied. We investigated the effect of resveratrol on ovalbumin-induced experimental allergic asthma in mice. To that end, BALB/c mice were immunized with ovalbumin (OVA) intraperitoneally followed by oral gavage of vehicle (OVA-veh) or resveratrol (100 mg/kg body) (OVA-res). On day 7, the experimental groups received intranasal challenge of OVA followed by 7 days of additional oral gavage of vehicle or resveratrol. At …

Communication, Democracy, And Intelligentsia, Dmitri N. Shalin

Sociology Faculty Research

In the early 1990s, a group of Russian and American scholars teamed up to investigate the impact of Gorbachev’s reform on Soviet society, focusing especially on the role the intelligentsia played in fomenting glasnost and perestroika. Results of this collaborative study were published in a volume Russian Culture at the Crossroads: Paradoxes of Postcommunist Consciousness (Shalin, 1996a). The contributors worked on the assumption that perestroika was an irreversible achievement, that distortions the reforms wrought in Russian society would be smoothed out over time. Today, this assumption appears overoptimistic. After nearly twenty years in power, Vladimir Putin dismantled key democratic institutions, …

Motivirani Zaposleni So Zaneseni Zaposleni: Vpliv Notranje Motivacije Na Zanos, Darija Aleksić

Economic and Business Review

Flow experience is associated with positive consequences in the work environment that promote commitment to work and organizational spontaneity, thereby contributing to the achievement of organizational goals, such as creativity and organizational performance. The aim of this paper is thus to answer the question of how to increase the frequency of flow at work. Specifically, this paper examines the influence of intrinsic motivation on flow experience. The results of an online experiment (n = 126) show that intrinsic motivation has a strong positive effect on two dimensions of flow: the balance between challenges and skills and the merger of action …

Micromagnetic Study On The Magnetization Reversal Of Barium Hexaferrite (Bafe12o19) Thin Film, Dede Djuhana, Dita Oktri, Candra Kurniawan

Makara Journal of Science

This study investigates a magnetization reversal mechanism based on the hysteresis curve of Barium Hexaferrite (BFO) thin film by micromagnetic simulation through parallel and perpendicular magnetization directions along the axes. The hexagonal shape of the BFO film was modeled with thicknesses of 5, 10, and 15 nm and a diameter size ranging from 50 to 100 nm. It was found that the coercivity field HC and the saturation field HS of the BFO film decreased as thediameter size increased and thickness decreased. It was observed that the nucleation field HN increased as the diametersize increased. An analysis of energies showed …

Making Prescriptions “Talk” To Stroke And Heart Attack Survivors To Improve Adherence: Results Of A Randomized Clinical Trial (The Talking Rx Study), Ayeesha Kamran Kamal, Wardah Khalid, Abdul Muqeet,, Anum Jamil,, Kashfa Farhat, Sehar Rahim Ali Gillani, Maryam Zulfiqar, Mehreen Saif, Aliya Amin Muhammad, Fabiha Zaidi, Saleem Sayani, Salim S. Virani

Section of Neurology

Background: We developed and tested the effectiveness of a tailored health information technology driven intervention: "TalkingPrescriptions" (Talking Rx) to improve medication adherence in a resource challenged environment.
Methods: We conducted a parallel, randomized, controlled, assessor-blinded trial at the Aga Khan University (AKU), Karachi, Pakistan. Adults with diagnosis of cerebrovascular accident (CVA) or coronary artery disease (CAD) diagnosed least one month before enrollment, on anti-platelets and statins, with access to a mobile phone were enrolled. The intervention group received a) Daily Interactive Voice Response (IVR) call services regarding specific statin and antiplatelet b) Daily tailored medication reminders for statin and antiplatelet …