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2018

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Structurally Supported Cell-Laden Scaffolds For Bone Tissue Regeneration, Stephen William Sawyer Dec 2018

Structurally Supported Cell-Laden Scaffolds For Bone Tissue Regeneration, Stephen William Sawyer

Dissertations - ALL

Due to challenges associated with current clinical techniques used to treat bone defects, there has been an increased focus on finding a tissue engineered solution. However, while great progress in this field has been achieved, researchers have yet to suitably combine the proper biological and structural environments needed to serve as a complete bone tissue substitute that is comparable to modern clinical solutions.

To achieve the goal of creating a model bone tissue substitute which could eventually serve as a viable therapy for bone trauma, be it caused by congenital medical conditions, age related diseases or high impact forces, three …


Deconvolution Of Membrane Protein-Detergent Complex Interactions, Aaron Wolfe Dec 2018

Deconvolution Of Membrane Protein-Detergent Complex Interactions, Aaron Wolfe

Dissertations - ALL

Membrane proteins are important in many biological functions such as cell-cell recognition, transport, and signaling; yet the study of these proteins is stunted due to their excessive aggregation in aqueous solutions. Detergents have been extensively exploited to mitigate this aggregation, and accomplish this by protecting the hydrophobic exterior of the membrane protein with their hydrophobic tails, while the polar heads of the detergents interact with the surrounding aqueous environment. Although detergents are of fundamental importance in many membrane protein studies, their selection is primarily done by trial and error screening. In this thesis, I will describe a method to utilize …


Chimera Ligand For Pili And Lectin A Protein Controls Antibiotic-Promoted Biofilm Formation, Swarming Motility, Tolerance And Persister Formation By Pseudomonas Aeruginosa, Hewen Zheng Dec 2018

Chimera Ligand For Pili And Lectin A Protein Controls Antibiotic-Promoted Biofilm Formation, Swarming Motility, Tolerance And Persister Formation By Pseudomonas Aeruginosa, Hewen Zheng

Dissertations - ALL

Throughout the human history, the fight against bacterial infections had never stopped but the remedies for bacterial infections were often insufficient and for many infectious diseases, there was no treatment available. The revolution in antimicrobial infection therapy began with the discovery of penicillin by Alexander Fleming in 1928. However, since the first introduction of antibiotics, bacteria over time have evolved sophisticated resistant strains against almost all the available antibiotics which cause selection pressure on the bacteria to evolve their genetic makeup and develop resistance against such agents. Furthermore, bacteria can form surface attached multicellular communities known as biofilms. Bacteria residing …


Predicting Accounting Misstatements Within Industries And Accounts, Emily Cokeley Dec 2018

Predicting Accounting Misstatements Within Industries And Accounts, Emily Cokeley

Dissertations - ALL

This study examines variables that may be useful in predicting accounting misstatements. Using a database of Accounting and Auditing Enforcement Release information and building on recent models and methodology, I separate the observations by industry to determine the firm and financial statement variables that are most useful in predicting the firms within specific industries that may have accounting misstatements. I also extend the previous models to determine the significant variables in predicting not only which firms may have misstatements, but also the account(s) in which a misstatement is likely to have occurred. These models use information that is readily available …


Archives Annual Report, 2017-2018, Meg Miner Dec 2018

Archives Annual Report, 2017-2018, Meg Miner

Administrative Reports

No abstract provided.


Protein Kinase A And High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization In Aspergillus Fumigatus, Leandro Jose De Assis, Adriana Manfiolli, Eliciane Mattos, João H.T.Marilhano Fabri, Iran Malavazi, Ilse D. Jacobsen, Matthias Brock, Robert A. Cramer, Arsa Thammahong, Daisuke Hagiwara, Laure Nicolas Annick Ries, Gustavo Henrique Goldman Dec 2018

Protein Kinase A And High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization In Aspergillus Fumigatus, Leandro Jose De Assis, Adriana Manfiolli, Eliciane Mattos, João H.T.Marilhano Fabri, Iran Malavazi, Ilse D. Jacobsen, Matthias Brock, Robert A. Cramer, Arsa Thammahong, Daisuke Hagiwara, Laure Nicolas Annick Ries, Gustavo Henrique Goldman

School of Biomedical Sciences

Aspergillus fumigatus is an opportunistic human pathogen causing allergic reactions or systemic infections such as invasive pulmonary aspergillosis, especially in immunocompromised patients. The fungal cell wall is the main component responsible for recognition by the immune system, due to the specific composition of polysaccharide carbohydrates exposed on the surface of the fungal cell wall called pathogen-associated molecular patterns (PAMPs). Key enzymes in the fungal cell wall biosynthesis are a good target for fungal drug development. This report elucidates the cooperation between the HOG and PKA pathways in the mobilization of carbohydrates for fungal cell wall biosynthesis. We suggest that the …


The Use Of Media Technologies In Long-Distance Relationships, Paola P. Soto Herrera Dec 2018

The Use Of Media Technologies In Long-Distance Relationships, Paola P. Soto Herrera

Theses

Communication technologies have helped reduce personal distances and stay connected. This study pursued the following questions: What are the most popular media used to communicate in long-distance relationships? Are those in long-distance relationships more likely to use rich or lean media? Do family, friends, and romantic partners differ in their selection of media? Instant Messaging, social media (Instagram, Facebook, Twitter, Snapchat), telephone (cellular, mobile, or landline), online video chat, online audio chat, SMS, and regular mail were the most used media. Respondents were significantly more likely to use rich media. Romantic partners were more likely than either family or friends …


Sustainable Development: The Role Of School Libraries, Abiola Bukola Elaturoti Dec 2018

Sustainable Development: The Role Of School Libraries, Abiola Bukola Elaturoti

Library Philosophy and Practice (e-journal)

Over the past few years, sustainable development has emerged the latest development slogan. Sustainable development has been defined as the development that meets the social, economic and technological needs of the present without compromising the ability of future generations to meet their own needs. A good well-equipped library is a prerequisite for the intellectual, moral, and spiritual advancement and elevation of an individual right from childhood; it is an indispensable element of the absolute well-being of the citizens and that of the nation at large. To attain sustainable development, the role of libraries, and particularly school libraries, cannot be ignored …


Review Of Moving Image And Sound Collections For Archivists, Lauren Sorensen Dec 2018

Review Of Moving Image And Sound Collections For Archivists, Lauren Sorensen

Journal of Contemporary Archival Studies

Review of Anthony Cocciolo's Moving Image and Sound Collections for Archivists.


“Tell Us About Your Digital Archives Workstation”: A Survey And Case Study, Elvia Arroyo-Ramírez, Kelly Bolding, Faith Charlton, Allison Hughes Dec 2018

“Tell Us About Your Digital Archives Workstation”: A Survey And Case Study, Elvia Arroyo-Ramírez, Kelly Bolding, Faith Charlton, Allison Hughes

Journal of Contemporary Archival Studies

Archival staff in the Manuscripts Division, Department of Rare Books and Special Collections (RBSC) at Princeton University Library lacked a fully-equipped digital processing workstation to capture, transfer, and secure born-digital and digitized archival content for long-term preservation and access. Staff recently conducted a survey that included information about the digital processing workstations of twenty institutions. The results of this survey informed a successful proposal to acquire a Forensic Recovery of Evidence Device (FRED) to serve as our digital processing workstation. The article will share details about the survey and considerations that went into our decision-making process, as well as introduce …


Special Issue School-To-Prison Pipeline, Taboo Journal Special Issue Dec 2018

Special Issue School-To-Prison Pipeline, Taboo Journal Special Issue

Taboo: The Journal of Culture and Education

No abstract provided.


A Student Saved Is Not A Dollar Earned: A Meta-Analysis Of School Disparities In Discipline Practice Toward Black Children, Jemimah L. Young, Jamaal R. Young, Bettie Ray Butler Dec 2018

A Student Saved Is Not A Dollar Earned: A Meta-Analysis Of School Disparities In Discipline Practice Toward Black Children, Jemimah L. Young, Jamaal R. Young, Bettie Ray Butler

Taboo: The Journal of Culture and Education

No abstract provided.


Latinx Youth Counterstories In A Court Diversion Program, Gerardo Mancilla Dec 2018

Latinx Youth Counterstories In A Court Diversion Program, Gerardo Mancilla

Taboo: The Journal of Culture and Education

No abstract provided.


Using Double Consciousness As An Analytic Tool To Discuss The Decision Making Of Black School Leaders In Disrupting The School-To-Prison Pipeline, Ramon Goings, Sheree Alexander, Julius Davis, Nicole M. Walters Dec 2018

Using Double Consciousness As An Analytic Tool To Discuss The Decision Making Of Black School Leaders In Disrupting The School-To-Prison Pipeline, Ramon Goings, Sheree Alexander, Julius Davis, Nicole M. Walters

Taboo: The Journal of Culture and Education

No abstract provided.


Restorative Justice As A Doubled-Edged Sword: Conflating Restoration Of Black Youth With Transformation Of Schools, Arash Daneshzadeh, George Sirrakos Dec 2018

Restorative Justice As A Doubled-Edged Sword: Conflating Restoration Of Black Youth With Transformation Of Schools, Arash Daneshzadeh, George Sirrakos

Taboo: The Journal of Culture and Education

No abstract provided.


Introduction: School-To-Prison Pipeline Special Issue, Ahmad Washington, Malik Henfield Dec 2018

Introduction: School-To-Prison Pipeline Special Issue, Ahmad Washington, Malik Henfield

Taboo: The Journal of Culture and Education

No abstract provided.


Micro Touchpad For Wearables, Chun Yat Li, Guangzhe Cui, Debanjan Mukherjee Dec 2018

Micro Touchpad For Wearables, Chun Yat Li, Guangzhe Cui, Debanjan Mukherjee

Defensive Publications Series

Users interact with electronic devices via a variety of input devices, such as buttons, touchpads, touchscreens, keyboards, styluses, and mice. Touchpads allow users to provide the electronic devices with a variety of commands and instructions because of their flexibility in receiving many types of input, including touches, swipes, gestures, taps, and holds from one or more fingers or other input devices. Touchpads also allow for robust construction and ergonomic variability in environments in which other input devices may not function as effectively. In particular, a micro touchpad sized for wearable devices, such as watches, activity trackers, or headphones, that retains …


A Novel 3d+Mea Approach To Authentic Engineering Education For Teacher Professional Development: Design Principles And Outcomes, Melissa Dyehouse, Adam L. Santone, Zahid Kisa, Ronald L. Carr, Rabieh Razzouk Dec 2018

A Novel 3d+Mea Approach To Authentic Engineering Education For Teacher Professional Development: Design Principles And Outcomes, Melissa Dyehouse, Adam L. Santone, Zahid Kisa, Ronald L. Carr, Rabieh Razzouk

Journal of Pre-College Engineering Education Research (J-PEER)

This paper describes the design principles and implementation of a novel approach for a K–12 teacher professional development (PD) program. The approach integrates training focused on development of model eliciting activities (MEAs) within authentic engineering design tasks, collaborative 3D model design and fabrication, and inspirational site visits with access to active engineers to enhance understanding of current issues faced by NASA aerospace researchers. Throughout the training, participants collaborated with program staff including engineering, 3D graphics, education, and MEA specialists to develop research-related MEAs with accompanying 3Dprinted manipulatives. The purpose of this article is to provide a framework for engineering education …


Soliton Mechanism Of Charge Transport In Branched Conducting Polymers And Verification Of Conservation Laws, H. Sh. Matyokubov, D. B. Babajanov Dec 2018

Soliton Mechanism Of Charge Transport In Branched Conducting Polymers And Verification Of Conservation Laws, H. Sh. Matyokubov, D. B. Babajanov

Central Asian Problems of Modern Science and Education

In this work we consider the modeling of charge transport processes in branched conducting polymers and verification of conservation laws, such as energy and charge conservation.


Diagnosis Of Learning Difficulties Edc 464, Joanna Burkhardt Dec 2018

Diagnosis Of Learning Difficulties Edc 464, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Supervised Practicum Elementary Education Edc 405, Joanna Burkhardt Dec 2018

Supervised Practicum Elementary Education Edc 405, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Positive Behavior Supports Edc 403, Joanna Burkhardt Dec 2018

Positive Behavior Supports Edc 403, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Supervised Practicum Elementary Education Edc 406, Joanna Burkhardt Dec 2018

Supervised Practicum Elementary Education Edc 406, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Vol.46 N.22 December 20th 2018, Voice Media Ventures Dec 2018

Vol.46 N.22 December 20th 2018, Voice Media Ventures

Black Voice News

No abstract provided.


The Internet Of Bodies: Life And Death In The Age Of Ai, Eleonore Pauwels, Sarah W. Denton Dec 2018

The Internet Of Bodies: Life And Death In The Age Of Ai, Eleonore Pauwels, Sarah W. Denton

California Western Law Review

No abstract provided.


The Emerging Artificial Intelligence Wellness Landscape: Benefits And Potential Areas Of Ethical Concern, Lydia Kostopoulos Dec 2018

The Emerging Artificial Intelligence Wellness Landscape: Benefits And Potential Areas Of Ethical Concern, Lydia Kostopoulos

California Western Law Review

No abstract provided.


Ethical Issues Of Artificial Intelligence In Medicine, Tokio Matsuzaki Dec 2018

Ethical Issues Of Artificial Intelligence In Medicine, Tokio Matsuzaki

California Western Law Review

No abstract provided.


Law Without Mind: Ai, Ethics, And Jurisprudence, Joshua P. Davis Dec 2018

Law Without Mind: Ai, Ethics, And Jurisprudence, Joshua P. Davis

California Western Law Review

No abstract provided.


Unvarnished Inhumanity: America’S Factory Farm Industry, Caitlin Rowley Dec 2018

Unvarnished Inhumanity: America’S Factory Farm Industry, Caitlin Rowley

Honors Program Theses and Projects

As exposed through a variance of media outlets, the United States is often inept in its endorsement of farm animal welfare laws; while incidents depicting the cruel mistreatment of farm animals are plentiful, the federal government enforces only two laws that address the issue directly. The 28 Hour Law and the Humane Methods of Slaughter Act, however pure in intent, are severely limited in scope, and according to reports from the USDA, handling violations are frequent yet rarely result in longstanding consequences. Consequently, this research provides a comprehensive overview of the activity within the factory farm industry so that, in …


Middle East Media Landscapes: Egypt, Libya, Tunisia, Syria, And Yemen, Cody J. Baker Dec 2018

Middle East Media Landscapes: Egypt, Libya, Tunisia, Syria, And Yemen, Cody J. Baker

Honors Program Theses and Projects

Following the youth-led reformative wave that swept the Middle East in 2011 during what came to be known as the Arab Spring, the media landscape in the region has continued to diversify and change alongside technology and social media. However, in order to deal with a large youth demographic that is seeking increased civil liberties and equality, and to prevent another series of protests, many governments are placing restrictions and limitations on the press, internet access, and censoring individuals who are critical of government or politically active. Through a critical analysis of the current media landscapes of five nations; Egypt, …