Digital Commons Network^™

Haemagglutinin-Neuraminidase From Hpiv3 Mediates Human Nk Regulation Of T Cell Proliferation Via Nkp44 And Nkp46, Samantha Mcquaid, Sinead Loughran, Patrick Power, Paula Maguire, Dermot Walls, Maria Grazia Cusi, Claes Orvell, Patricia Johnson

Articles

HPIV3 is a respiratory virus causing airway diseases, including pneumonia, croup, and bronchiolitis, during infancy and childhood. Currently there is no effective vaccine or anti-viral therapy for this virus. Studies have suggested that poor T cell proliferation following HPIV3 infection is responsible for impaired immunological memory associated with this virus. We have previously demonstrated that NK cells mediate regulation of T cell proliferation during HPIV3 infection. Here we add to these studies by demonstrating that the regulation of T cell proliferation during HPIV3 infection is mediated via NK receptors NKp44 and NKp46 and involves the surface glycoprotein haemagglutinin-neuraminidase but not …

Resist: A Controversial Display And Reflections On The Academic Library’S Role In Promoting Discourse And Engagement, Stephanie Beene, Cindy Pierard

Urban Library Journal

Libraries engage communities in a variety of ways, including through exhibitions and displays. However, librarians may not always know how to promote critical discourse if controversy arises surrounding exhibits or displays. This article reflects on one academic library’s experience hosting a controversial display during a divisive political time for the library’s parent institution, its broader urban community, and the United States as a whole. The authors contextualize the display, created by a local art collective, against the backdrop of creative activism, and consider implications for library displays and exhibits within similar environments. Rather than retreating from controversy, libraries have an …

A Blueprint For Knowledge Management In The Biopharmaceutical Sector, Paige Kane

Doctoral

This research examined current industry Knowledge Management (KM) methodologies and capabilities in order to gain insights into the level of maturity and understanding of KM within the biopharmaceutical sector. In addition, the researcher has developed models, tools and processes that can assist the sector to gain greater clarity of the value and merits that KM can offer to organizations. The researcher proposes that a systematic KM program can be used to “unlock” the knowledge and organizational capabilities necessary to convey real competitive advantage, but more importantly for the patient, to enable organizations to successfully develop and deliver the next generation …

Evaluation Of A Drug Delivery System Based On Cyclodextrins For Cancer Therapy, Caroline Mendes

Doctoral

Due to the side-effects caused by regular chemotherapy, the development of drug delivery systems that can specifically target cancer cells and deliver the therapeutic dose is required. In this study, a folate-derivative of β-cyclodextrin has been studied as a vehicle for targeting folate receptors (FR) and delivering the chemotherapeutic drug methotrexate (MTX). FRs can be considered key cell membrane targets since they are commonly over-expressed in cancer cells and play an important role in cancer development and progression. Cyclodextrins (CDs) are cyclic oligosaccharides with a unique structure that allows them to form inclusion complexes with guest molecules, increasing their aqueous …

Fluid-Dynamic Models Of Geophysical Waves, Alan Compelli

Doctoral

Geophysical waves are waves that are found naturally in the Earth's atmosphere and oceans. Internal waves, that is waves that act as an interface between uids of dierent density, are examples of geophysical waves. A uid system with a at bottom, at surface and internal wave is initially considered. The system has a depth-dependent current which mimics a typical ocean set-up and, as it is based on the surface of the rotating Earth, incorporates Coriolis forces. Using well established uid dynamic techniques, the total energy is calculated and used to determine the dynamics of the system using a procedure called …

Three Decades Of Universal Design - Defining Moments, Margaret Kinsella

Articles

This paper contributes to the growing research on incorporating Universal Design in the Higher Education landscape by presenting a Practitioner's Perspective on Universal Design as delivered in the Institute of Technology, Blanchardstown (ITB) in the first year of a creative digital media degree as part of the first year experience. This first year experience is a transition time for many students and has many complexities; while being an exciting and fulfilling time, the transition can also be challenging and isolating. Through Universal Design, the aim is to enable students to 'Get connected' and 'Stay connected'. Universal Design for Learning is …

Relating Group Size And Posting Activity Of An Online Community Of Financial Investors: Regularities And Seasonal Patterns, P. Racca, R. Casarin, Pierpaolo Dondio, F. Squazzoni

Articles

Group size can potentially affect collective activity and individual propensity to contribute to collective goods. Mancur Olson, in his Logic of Collective Action, argued that individual contribution to a collective good tends to be lower in groups of large size. Today, online communication platforms represent an interesting ground to study such collaborative dynamics under possibly different conditions (e.g., lower costs related to gather and share information). This paper examines the relationship between group size and activity in an online financial forum, where users invest time in sharing news, analysis and comments with other investors. We looked at about 24 million …

Experienced Mental Workload, Perception Of Usability, Their Interaction And Impact On Task Performance, Luca Longo

Articles

No abstract provided.

Hating Hate Speech: Why Current First Amendment Doctrine Does Not Condemn A Careful Ban, Rory Little

Faculty Scholarship

No abstract provided.

A Taxonomy For Tax Loopholes, Heather M. Field

Faculty Scholarship

No abstract provided.

Offshoring Tax Ethics: The Panama Papers, Seeking Refuge From Tax, & Tax Lawyer Referrals, Heather M. Field

Faculty Scholarship

No abstract provided.

Monetizing Shame: Mugshots, Privacy, And The Right To Access, Eumi K. Lee

Faculty Scholarship

No abstract provided.

Final Report Of The Berkeley Center For Law & Technology Section 101 Workshop: Addressing Patent Eligibility Challenges, Jeffrey A. Lefstin, Peter S. Menell, David O. Taylor

Faculty Scholarship

No abstract provided.

Our Imperiled Absolutist First Amendment, Zachary S. Price

Faculty Scholarship

No abstract provided.

Legal Approaches To Promoting Parental Compliance With Childhood Immunization Recommendations, Lois A. Weithorn, Dorit Rubinstein Reiss

Faculty Scholarship

No abstract provided.

Regulating In The Era Of Fake News: Anti-Vaccine Activists Respond To The Cdc Quarantine Rule, Dorit Rubinstein Reiss

Faculty Scholarship

No abstract provided.

Legal Approaches To Promoting Parental Compliance With Childhood Immunization Recommendations, Dorit Rubinstein Reiss, Lois A. Weithorn

Faculty Scholarship

No abstract provided.

The Sound & Fury Of Patent Activity, Robin Feldman, Mark A. Lemley

Faculty Scholarship

No abstract provided.

Resolution Triggers For Systemically Important Financial Institutions, John Crawford

Faculty Scholarship

No abstract provided.

Disrupting Regulation, Regulating Disruption: The Politics Of Uber In The United States, Veena B. Dubal, Ruth Berins Collier, Christopher L. Carter

Faculty Scholarship

No abstract provided.

California's Drug Transparency Law: Navigating The Boundaries Of State Authority On Drug Pricing, Jaime S. King, Katherine L. Gudiksen, Timothy T. Brown, Christopher M. Whaley

Faculty Scholarship

No abstract provided.

Association Of Legal Intervention Injuries With Race And Ethnicity Among Patients Treated In Emergency Departments In California, Aaron J. Rappaport, Alyssa C. Mooney, Shannon Mcconville, Renee Y. Hsia

Faculty Scholarship

No abstract provided.

A Persistência Das Desigualdades Raciais No Sistema De Justiça Criminal Dos Eua, George Bisharat

Faculty Scholarship

No abstract provided.

May Your Drug Price Be Evergreen, Robin Feldman

Faculty Scholarship

No abstract provided.

Safeguarding Development: Risk Reduction In Us Government Foreign Aid And Investment Facilitation Beyond The Current Patchwork, Naomi Roht-Arriaza

Faculty Scholarship

No abstract provided.

Artificial Intelligence: The Importance Of Trust & Distrust, Robin Feldman

Faculty Scholarship

No abstract provided.

Sanctuary Networks As Integrative Enforcement, Ming Hsu Chen

Faculty Scholarship

intended focus is on the widespread response—in cities, churches, campuses, and corporations that together comprise “sanctuary networks”1—to the Trump Administration’s Executive Order 13768 Enhancing Public Safety in the Interior of the United States2 as an instance of the changing relationship between federal, local, and private organizations in the regulation of immigration. After briefly covering the legal background of the Trump Interior E.O., the focus of the Article shifts to the institutional dynamics arising in communities. These institutional dynamics exemplify the beginnings of a reimagi cement policy with a more integrative flavor.

Foreword To The West Virginia Law Review Appalachian Justice Symposium, Jennifer D. Oliva

Faculty Scholarship

No abstract provided.

Institutional Budget And Impact Of Internally Generated Revenue On Funding Of Academic Library In A Developing Economy, Tolulope Tosin Ogunjimi, Mujidat Adeola Bello, Olanike Oladunni Olaniyi

Library Philosophy and Practice (e-journal)

Provision of funds for the academic libraries has been one of the challenges to adequate availability of information resources. Most institutions rely on institutional revenues to be made available to the libraries at appropriate and available period.

The study showcased among others; determined the percentage of institutional budget of internally generated revenue for funding of the academic libraries, gathered information on products and services that generate income into academic libraries, exposed ways through which academic libraries could generate funds for self-dependence.

The instrument used for data collection was the questionnaire and study employed descriptive design to investigate the percentage of …

Evaluation Of Students’ Access To Serial Publications In Three Selected Universities In Ogun State, Nigeria, Susanah O. Tomomowo-Ayodele Mrs, Ayobami Bakare Hameed Mr.

Library Philosophy and Practice (e-journal)

This study evaluates the extent to which serials publications are accessible and used for learning purposes by the students in Nigerian Universities. The descriptive survey research design was adopted with the study population made up of students from one federal government owned university, one selected state owned university and one selected private owned university in Ogun state. A self-constructed questionnaire was used for data collection in this study, was analyzed using descriptive statistics and Statistical Package for Social Scientists (SPSS). Findings revealed that Nigeria university students have access to different serial collections in academic libraries. Serial publications are available and …