Digital Commons Network^™

Determinants And Characteristics Of Tuberculosis In Liver Transplant Recipients, Ayli̇n Özgen Alpaydin, Mücahi̇t Özbi̇lgi̇n, Madina Abdullayeva, Selver Seda Mersi̇n, Tufan Egeli̇, Tarkan Ünek, Oğuz Kilinç, İbrahi̇m Kemal Astarcioğlu, Vi̇ldan Avkan Oğuz

Turkish Journal of Medical Sciences

Background/aim: Solid organ transplant (SOT) recipients have increased risk of tuberculosis (TB). We aimed to investigate the prevalence and features of TB in liver transplant (LT) recipients at our transplantation canter. Materials and methods: All patients who underwent LT between January 2004 and December 2013 and whose data were accessible were included in the study. Demographic features, tuberculin skin test (TST) results, and TB prevalence were recorded. Characteristics of LT recipients who developed TB were evaluated. Results: A total of 403 patients underwent LT during this period. Mean age was 47.27 ± 11.04 years; 280 (69.47%) were males. The TST …

Angiostatin Levels In Diabetes Mellitus Patients Receiving Insulin Treatment: Associations With Laboratory Findings, Comorbidities, And Medications, İsmai̇l Ertürk, Erdi̇m Sertoğlu, Fati̇h Yeşi̇ldal, Ramazan Acar, Taner Özgürtaş, Kenan Sağlam

Turkish Journal of Medical Sciences

Background/aim: The clinical effect of angiostatin in diabetes mellitus (DM) patients receiving insulin is a meaningful gap in the literature. In this study, we aimed to show the levels and the clinical significance of angiostatin in DM patients receiving insulin. Materials and methods: This is a case-control study. Serum angiostatin levels were determined by ELISA. A total of 83 people consisting of healthy subjects (n = 36) and patients with a diagnosis of DM receiving insulin therapy (n = 47) were included in this study. Results: The mean angiostatin levels of the DM group were significantly higher than those of …

The Psychometric Evaluation Of The Turkish Version Of The Mann Assessment Of Swallowing Ability In Patients In The Early Period After Stroke, Ebru Karaca Umay, İbrahi̇m Gündoğdu, Eda Gürçay, Erhan Ari̇f Öztürk, Volkan Yilmaz, Özgür Zeli̇ha Karaahmet, Yasemi̇n Eren, Güleser Saylam, Fatma Aytül Çakci

Turkish Journal of Medical Sciences

Background/aim: The Mann Assessment of Swallowing Ability (MASA) is an efficient tool that allows physicians to determine the alertness, cooperation, and respiration of patients, which are important factors when assessing swallowing . This study aimed to translate the MASA into Turkish (T-MASA) and to assess its reliability and validity in patients during the early period after a stroke . Materials and methods: The scale was administered to 141 patients in the early period after a stroke. For reliability, both internal consistency (Cronbach's alpha and corrected item-to-total correlations) and interrater reliability were analyzed. The procedures were scored by two blinded independent …

Investigation Of The Effect Of Combined Use Of Alloplastic-Based Tricalcium Phosphate Bone Graft And Antihemorrhagic Plant Extract (Abs) On Bone Regeneration In Surgically Induced Bone Defects In Nondiabetic Rats: An Experimental Animal Study, Abdulsamet Tani̇k, Arzum Güler Doğru, Veysi̇ Akpolat, Fi̇li̇z Acun Kaya, Ebru Saribaş, Mehmet Gül, Sevgi̇ İrtegün, Engi̇n Deveci̇

Turkish Journal of Medical Sciences

Background/aim: In this experimental study, we aimed to evaluate the late period effects of the combination of Ankaferd Blood Stopper (ABS), which has bone wound healing effects, and ß-tricalcium phosphate (TCP) on the regeneration of bone tissue through histopathological, immunohistochemical, and radiological (dual energy X-ray absorptiometry - DEXA) methods in nondiabetic rats. Materials and methods: Sixty-four Wistar albino male rats were used. In the calvaria of the rats, a bone defect 7.0 mm in diameter was created. These rats were divided into 4 different groups. Group 1 was the control group without any treatment, a 0.125 mL B-TCP graft was …

Classifying Facts And Opinions In Twitter Messages: A Deep Learning-Basedapproach, Ronghua Shan, Swayambhu P. Chatterjee, Shuyuan Deng, Jun Liu, Wu Jiao

Research & Publications

Massive social media data present businesses with an immense opportunity to extract useful insights. However, social media messages typically consist of both facts and opinions, posing a challenge to analytics applications that focus more on either facts and opinions. Distinguishing facts and opinions may significantly improve subsequent analytics tasks. In this study, we propose a deep learning-based algorithm that automatically separates facts from opinions in Twitter messages. The algorithm outperformed multiple popular baselines in an experiment we conducted. We further applied the proposed algorithm to track customer complaints and found that it indeed benefits subsequent analytics applications.

Understanding Barriers To Genetic Testing For Sickle Cell Trait: The African-American Male Perspective, Shandrea Foster

Theses and Dissertations

Research has shown a reluctance in African-American males to pursue testing for sickle cell trait. Few studies have tried to discern what barriers are contributing to this issue within the African-American male community. Research suggests a lack of knowledge may be the biggest contributing factor. This study hypothesized there would be a significant difference in knowledge of sickle cell trait based on educational level, age, and health beliefs. African-America male participants (N=116), ages 18 and over, completed a questionnaire assessing knowledge, risk perception, health beliefs, barriers, and motivating factors within the context of sickle cell trait. One-way and two-way analysis …

Characterizing Health Behavior Information: Developing A Surveillance Text Mining Framework Using Twitter For Diet, Diabetes, Exercise, And Obesity, George Shaw Jr.

Theses and Dissertations

Previous studies have documented the relationship that exists among diabetes, diet, exercise, and obesity. Obesity increases people’s risk of developing heart disease and type 2 diabetes. Exercise and proper dieting are modifiable lifestyle behaviors that can help with reducing people’s overall weight and risk to various chronic conditions like diabetes. A national survey conducted by the Centers for Diseases Control and Prevention (CDC) is the annual Behavioral Risk Factor Surveillance Survey (BRFSS). Twitter provides researchers with a new opportunity and alternative data source to collect information regarding health behaviors using real-time data. Previous studies have demonstrated Twitter’s ability to monitor …

Initiating The Loeb Criteria In Long-Term Care, Janice Khauslender

Theses and Dissertations

Urinary tract infections are one of the most commonly reported infections in long-term care. Current practices often rely on non-specific symptoms, rather than specific genitourinary symptoms, to aid in the decision to obtain a urine culture. The literature does not support this practice due to the high prevalence of asymptomatic bacteriuria among long-term care patients, which does not have adverse outcomes when untreated. Antibiotics do not eradicate asymptomatic bacteriuria and place patients at risk of adverse reactions and increased risk of multi-drug resistant organisms. This clinical improvement project applied the Loeb criteria in two long-term care facilities to reduce the …

Understanding The Impact Of Land Use On Microbial Water Quality To Support Decisions For A Future Land Use Plan, Mohammed Tawfiq Aljassim

Theses and Dissertations

May River meandering through the Town of Bluffton, South Carolina has been known for its high level of water quality. The May River is one of the major sources of shellfish harvesting in South Carolina. Due to the non-point source pollution of fecal coliform, the water quality of the May River became degraded. As a result, shellfish harvesting classification in the May River was downgraded for the first time in its history. The rapid growth of the Town has led to a change in land use, which might be related to the increased levels of fecal coliform in the stream …

Evaluation And Testing Of Eye, Nose, And Mouth Protection For Biological Hazards To Support A Consensus Standard, Jeremy R Gouzd

Graduate Theses, Dissertations, and Problem Reports (ETD)

No abstract provided.

Vitamin E Status Is Inversely Associated With Risk Of Incident Tuberculosis Disease Among Household Contacts, Omowunmi Aibana, Molly F Franke, Chuan-Chin Huang, Jerome T Galea, Roger Calderon, Zibiao Zhang, Mercedes C Becerra, Emily R Smith, Carmen Contreras, Rosa Yataco, Leonid Lecca, Megan B Murray

Faculty, Staff and Student Publications

BACKGROUND: Few studies have previously assessed how pre-existing vitamin E status is associated with risk of tuberculosis (TB) disease progression.

OBJECTIVE: We evaluated the association between baseline plasma concentrations of 3 vitamin E isomers (α-tocopherol, γ-tocopherol, and δ-tocopherol) and TB disease risk.

METHODS: We conducted a case-control study nested within a longitudinal cohort of household contacts (HHCs) of pulmonary TB cases in Lima, Peru. We defined cases as HHCs who developed active TB disease ≥15 d after the diagnosis of the index patient, and we matched each case to 4 control cases who did not develop active TB based on …

A Study Of Hormonal Effects In Cervical Smear Samples Using Raman Spectroscopy, D. Traynor, P. Kearney, I. Ramos, C. M. Martin, J. J. O'Leary, Fiona Lyng

Articles

Raman spectroscopy is a powerful tool that has the potential to be used as a screening method for cervical cancer. It is a label-free, low-cost method providing a biochemical fingerprint of a given sample. The objective of this study was to address patient-to-patient variability contributed by hormonal effects due to the menstrual cycle, the use of hormone-based contraceptives (HC) and the onset of menopause, and to determine if these changes would affect the ability to successfully identify dyskaryotic cells. Raman spectra were recorded from unstained ThinPrep cervical samples (45 cytology negative and 15 high-grade dyskaryosis (high-grade squamous intraepithelial lesion, HSIL) …

Influences Of Forest Edges And Human Activities On The Dry Season Ranging Patterns Of Chimpanzees (Pan Troglodytes Schweinfurthii) In Nyungwe National Park, Rwanda, Enathe Hasabwamariya

Antioch University Dissertations & Theses

Great apes, our closest biological relatives are threatened globally by the increasing anthropogenic pressures on their habitat. The major threats to the eastern chimpanzees (Pan troglodytes schweinfurthii) are hunting for bush meat and illegal trade in chimpanzee infants, habitat loss or fragmentation and disease transmission (IUCN, 2010). Nyungwe National Park (NNP), Rwanda has a population of chimpanzees that face several threats, including hunting for bushmeat, habitat degradation from forest fires and human-wildlife conflicts, and much of these impacts are concentrated at forest edges. The main objectives of this research were to assess the use of forest edges by chimpanzees along …

Limb Salvage For Diabetic Patients With Peripheral Arterial Disease, Jamie Jesse Johnson

Physician Assistant Scholarly Project Papers

Diabetes is rapidly increasing throughout the United States. According to the Center for Disease Control (CDC) (2017), the total number of patients diagnosed with diabetes is 23.1 million, patients with undiagnosed diabetes are 7.2 million, for a combined total number of patients with diabetes exceeding 30.2 million and growing.

According to the CDC (2016), approximately 8.5 million people in the United States have peripheral artery disease (PAD), which includes 12-20% of individuals who are older than age 60. According to a study performed by Swaminathan et al. (2014), 186,000 patients underwent lower extremity amputation (LEA). Data also shows that patients …

Introgression In Native Populations Of Apis Mellifera Mellifera L: Implications For Conservation, Jonathan S. Ellis, Gabriele Soland-Reckeweg, Victoria G. Buswell, J. Vanessa Huml, Andrew Brown, Mairi E. Knight

School of Biological and Marine Sciences

No abstract provided.

Prenatal Lactation-Focused Motivational Interviewing For Enhancing Breastfeeding Initiation, Exclusivity, And Duration: Feasibility And Preliminary Outcomes, Sarah H. Addicks

Graduate Theses, Dissertations, and Problem Reports (ETD)

Breastfeeding promotes health and well-being for both mother and infant. A variety of environmental and individual factors, including psychological ones, affect infant feeding practices. The purpose of this study was to determine the feasibility and effectiveness of a single-session Motivational Interviewing (MI) intervention delivered during the third trimester of pregnancy for enhancing breastfeeding outcomes. The Theory of Planned Behavior provided a theoretical framework for the intervention and outcome measures. The sample consisted of predominantly rural participants living in the North Central Appalachian region. Women were recruited through social media, local clinics, and word of mouth. Participants (N = 81) completed …

Parasitaemia Data And Molecular Characterization Of Haemoproteus Catharti From New World Vultures (Cathartidae) Reveals A Novel Clade Of Haemosporida, Michael J. Yabsley, Ralph E.T. Vanstreels, Ellen S. Martinsen, Alexandra G. Wickson, Amanda E. Holland, Sonia M. Hernandez, Alec T. Thompson, Susan L. Perkins, Christopher A. Lawrence Bryan, Christopher A. Cleveland, Emily Jolly, Justin D. Brown, Dave Mcruer, Shannon Behmke, James C. Beasley

Faculty & Staff Scholarship

Background: New World vultures (Cathartiformes: Cathartidae) are obligate scavengers comprised of seven species in five genera throughout the Americas. Of these, turkey vultures (Cathartes aura) and black vultures (Coragyps atratus) are the most widespread and, although ecologically similar, have evolved differences in morphology, physiology, and behaviour. Three species of haemosporidians have been reported in New World vultures to date: Haemoproteus catharti, Leucocytozoon toddi and Plasmodium elongatum, although few studies have investigated haemosporidian parasites in this important group of species. In this study, morphological and molecular methods were used to investi- gate the epidemiology and molecular biology of haemosporidian parasites of …

Cluster-Based Network Proximities For Arbitrary Nodal Subsets, Kenneth S. Berenhaut, Peter S. Barr, Alyssa M. Kogel, Ryan L. Melvin

Faculty & Staff Scholarship

The concept of a cluster or community in a network context has been of considerable interest in a variety of settings in recent years. In this paper, employing random walks and geodesic distance, we introduce a unified measure of cluster-based proximity between nodes, relative to a given subset of interest. The inherent simplicity and informativeness of the approach could make it of value to researchers in a variety of scientific fields. Applicability is demonstrated via application to clustering for a number of existent data sets (including multipartite networks). We view community detection (i.e. when the full set of network nodes …

Eastern Oyster Larval Transcriptomes In Response To Probiotic And Pathogenic Bacteria, Tejashree Modak

Open Access Dissertations

Oysters are described as keystone species serving an important ecological role. As filter-feeders they help in maintaining water quality. Oyster reefs provide refuge and support to different organisms. The eastern oyster, Crassostrea virginica, native to the East Coast of United States and Gulf of Mexico is a part of the rapidly growing aquaculture industry. Aquaculture production depends on a healthy and constant supply of oyster larvae that are provided by hatcheries. Several hatcheries on the east coast that provide C. virginica seed to oyster farms face significant losses owing to Vibrio infections causing massive larval mortalities. Use of antibiotics …

Assessment Of Melanistic Lesions In Smallmouth Bass ( Micropterus Dolomieu) Of The Chesapeake Bay, Usa, Kelsey T. Young

Graduate Theses, Dissertations, and Problem Reports (ETD)

Smallmouth bass (Micropterus dolomieu) are an important sportfish in the Susquehanna and Potomac River Basins of the Chesapeake Bay drainage. However, population declines in portions of the Susquehanna, fish kills and reports of visible abnormalities such as melanistic spots have raised concern among the public and resource managers. Although the etiology or risk factors associated with melanistic lesions are unknown, there is a propensity to attribute the abnormality to contaminants. Melanistic lesions of smallmouth bass were assessed using histopathology and gene expression analysis to evaluate the cellular and molecular changes compared to normal skin. The prevalence of melanistic …

Understanding Transgender Prejudice Through The Lens Of Emotion, Holly N. Fitzgerald

Graduate Theses, Dissertations, and Problem Reports (ETD)

Transgender individuals report facing incidents of discrimination often in all aspects of their lives (James et al., 2016). A potential way to combat the discrimination transgender people face is through reducing transgender prejudice. However, it is not yet known what comprises transgender prejudice. Some research has found that emotions may be the more predominant determinant of prejudice, as opposed to stereotypes (Dasgupta, Desteno, Williams, & Hunsinger, 2009; Haddock, Zanna, & Esses, 1993a; Smith, 1993). Thus, the present research sought to identify the specific emotions associated with transgender prejudice. In Study 1, participants completed explicit and implicit measures of prejudice and …

Ground-Dwelling Songbirds As Reservoirs And Carriers Of Tickborne Disease (Lyme Disease), Amanda Jayne Hill

Graduate Theses, Dissertations, and Problem Reports (ETD)

No abstract provided.

Satellite Based Predictability Of Water Sensitive Infectious Diseases, Md. Rakibul Hassan Khan

Graduate Theses, Dissertations, and Problem Reports (ETD)

No abstract provided.

Exploratory Longitudinal, Spatial And Spatiotemporal Evaluation Of The Raccoon Variant Rabies Virus In West Virginia, 2000- 2015, Kenneth. B Plants

Graduate Theses, Dissertations, and Problem Reports (ETD)

No abstract provided.

Dispositional Optimism And Autonomic Reactivity During Difficult And Easy Stress Tasks, Daniel Stephenson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Studies examining the association between dispositional optimism and autonomic reactivity to stress have yielded mixed results, with some studies finding associations between optimism and less reactivity, some studies finding no association between optimism and reactivity, and some finding that optimism was associated with greater reactivity. One factor not considered previously in this literature is difficulty of the stressful task employed to elicit autonomic reactivity. The current study was based on Carver and Scheier's Behavioral Self-Regulation Model (Carver & Scheier, 2000), that states that optimists are more likely to persist in overcoming challenging obstacles than pessimists. The current study investigated whether …

Characterization Of Marital Violence Using Data From Six Countries In The World Health Organization World Mental Health Survey Initiative, Cara Mangine Stokes

Graduate Theses, Dissertations, and Problem Reports (ETD)

Intimate partner violence (IPV) is a pervasive global public health problem that occurs in all settings and cultural groups. Traditionally, IPV research has largely focused on identifying risk factors from those who have already been victimized. In contrast to descriptive statistics, this project utilized predictive modeling methods to develop a robust model to predict risk for IPV, defined as moderate physical violence occurring within current marriages. Data for this project come from six countries participating in the World Health Organization (WHO) World Mental Health (WMH) Survey Initiative. Analyses capitalized on the availability of data containing detailed pre-marital factors from both …

Perceptions Of Private Medical Practitioners Towards The Nigerian National Tuberculosis Treatment Guidelines, Chijioke Pius Osakwe

Walden Dissertations and Doctoral Studies

Tuberculosis (TB) is a major public health problem in many parts of the world. Nigeria is one of the 30 countries in the world that has the highest burden of TB. Private medical practitioners in Nigeria play an important role in health care delivery. Motivating them to adhere to TB treatment guidelines in managing persons suspected of having TB or diagnosed with the disease is one of the strategies employed by the National Tuberculosis Program to Reduce the Burden of TB. Few studies were identified which used qualitative study approaches to study the perceptions of these practitioners towards the TB …

Educational Module On Health Literacy For Hypertension In The Inmate Population, Pamela Mokoko

Walden Dissertations and Doctoral Studies

Hypertension is a major public health issue in the United States that affects approximately 70 million adults; the high blood pressure of nearly half is considered to be uncontrolled. Uncontrolled hypertension is especially true in the incarcerated population. Due to low health literacy on hypertension in the inmate population, there are recurrent hospital visits, an increase in the admission rate and an increased length of stay in hospitals, all of which may lead to an increase in the cost of healthcare. The purpose of this scholarly project was to develop an expertly reviewed, evidence-based, self-paced, computerized, educational module to promote …

Oral Care And The Connection To Adverse Events In Dentistry, Melissa A. Rhoney

Walden Dissertations and Doctoral Studies

As the healthcare industry continues to change, dental providers are concerned about the different types of adverse events that can occur if systemic diseases are not well understood when treating patients. The purpose of this study was to explore the level of understanding among dental care providers of the relationship between oral care and systemic diseases and how these are linked to adverse events. The theoretical foundation that was used for this study was the Swiss cheese model. The research questions were designed to address the level of understanding among dental care providers of the link between oral care and …

Inpatient Rehabilitation, Diabetes, And The Risk Of Clostridium Difficile Infection, Kerry A. Flint

Walden Dissertations and Doctoral Studies

Clostridium difficile is a frequent cause of healthcare-associated infections (HAI) and is associated with increased risk of morbidity and mortality. Studies suggest environmental and host characteristics increase patient's susceptibility to C. difficile infection (CDI). However, few studies have examined the risk of CDI among those with diabetes or patients in the acute rehabilitation (AR) setting. A case-control study, using secondary data (n = 473), evaluated the relationship between CDI and diabetes and identified modifiable environmental exposures. An ecosocial framework was used to examine the relationship between these two complex diseases among hospitalized patients in an AR setting. Results of the …