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The Diagnostic Role Of Pentraxin-3 In The Differential Diagnosis Of Pleural Effusions, Fatma Çi̇ftci̇, Gülden Bi̇lgi̇n, Ayşe Naz Özcan, Özlem Doğan, Aycan Yüksel, Serhat Erol, Aydin Çi̇ledağ, Akin Kaya

Turkish Journal of Medical Sciences

Background/aim: Discrimination of pleural effusion etiology is not always easy in clinical practice. Pentraxin-3 (PTX-3) is a new acute- phase protein. The aim of this study was to investigate the role of PTX-3 in the differential diagnosis of pleural effusions. Materials and methods: This prospective study enrolled all consecutive patients from two tertiary hospitals who underwent diagnostic or therapeutic thoracentesis. In a cohort of 149 subjects with pleural effusion, including transudates and malignant (MPE), tuberculous (TPE), and parapneumonic effusion (PPE), serum and pleural effusion PTX-3 concentration measurements were performed using ELISA. Serum and pleural effusion protein, lactate dehydrogenase, C-reactive protein …

The Role Of Soluble Urokinase Plasminogen Activator Receptor (Supar) As An Indicator Of The Severity Of Acute Pancreatitis, Kadi̇r Küçükceran, Mehmet Ergi̇n, İbrahi̇m Kilinç, Adnan Karai̇brahi̇moğlu, Tamer Çolak, Alpay Tuncar, Zerri̇n Defne Dündar, Sedat Koçak, Abdullah Sadik Gi̇ri̇şgi̇n, Mehmet Gül, Başar Cander

Turkish Journal of Medical Sciences

Background/aim: Soluble urokinase plasminogen activator receptor (suPAR) has been reported to have a positive correlation with the activation degree of the immune system. This study's aim is to investigate the efficiency of SuPAR serum levels in acute pancreatitis (AP) patients in determining the severity of disease. Materials and methods: This prospective research involves patients who arrived at the emergency service, were over 18 years old, had nontraumatic abdominal pain and diagnosis of AP, and agreed to join the study. Demographic characteristics, contact information, laboratory and imaging test parameters, Ranson's criteria, the Balthazar Severity Index, the Rapid Acute Physiologic Score (RAPS), …

Expression Changes Of Cd177 And Mpo As Novel Biomarkers In Lung Tissue Ofclp Model Rats, Azadeh Rasooli, Elham Ghafari, Hamed Saeidi, Saba Miri

Turkish Journal of Medical Sciences

Background/aim: Sepsis is an unregulated systemic response to microbial invasion that can lead to multiple organ failure. This study aims at investigating the relationships among myeloperoxidase (MPO) and CD177 in major organ systems including whole blood, liver, and lung tissues in septic rats. Materials and methods: Sepsis was induced by cecal ligation and puncture (CLP) in female Wistar rats. Whole blood, liver, and lung samples were obtained from rats of 3 groups (n = 10 for each group, n total = 30: control as a wild-type group, laparotomy group (LAP), and CLP). Gene expression of MPO and CD177 in targeted …

Evaluation Of The Performance Of Maldi-Tof Ms And Dna Sequence Analysis In The Identification Of Mycobacteria Species, Işin Akyar, Cengi̇z Çavuşoğlu, Meltem Ayaş, Süheyla Sürücüoğlu, Zeynep Arzu İlki̇, Deni̇z Ece Kaya, Yeşi̇m Beşli̇

Turkish Journal of Medical Sciences

Background/aim: Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is an alternative way of identifying mycobacteria via the analysis of biomolecules. It is being increasingly used in routine microbiology practice since it permits early, rapid, and cost-effective identification of pathogens of clinical importance. In this study, we aimed to evaluate the efficacy of phenotypic identification of mycobacteria by the MALDI-TOF MS MBT Mycobacteria Library (ML) 4.0 (Bruker, Daltonics) compared to standard sequence analysis. Materials and methods: A total of 155 Mycobacterium clinical and external quality control isolates, comprising nontuberculous mycobacteria (NTM) (n = 95) and the Mycobacterium tuberculosis complex (MTC) (n …

Antibody Dependent Enhancement Of Visceral Leishmaniasis, Alan K. Mcnolty

All Master's Theses

Leishmaniasis is a parasitic disease caused by protozoans of the genus Leishmania. This vector-born disease, transmitted by biting phlebotomine sandflies, typically manifests in one of three ways. The cutaneous form of the disease is characterized by localized lesions of the skin and is by far the most common manifestation. The visceral form of the disease is caused by parasitic infiltration of internal organs, particularly the spleen, liver, and bone marrow. The mucocutaneous form is caused by parasitic infection of the mucosa in the nose or mouth. While cutaneous leishmaniasis (CL) is often self-healing, visceral leishmaniasis (VL) is fatal if …

Demographic And Clinical Predictors Of Trait Impulsivity In Parkinson’S Disease Patients, Maddeson Riley, Megan Bakeberg, Michelle Byrne, Alexa Jefferson, Soumya Ghosh, Rick Stell, Frank L. Mastaglia, Dana A. Hince, Ryan S. Anderton

Health Sciences Papers and Journal Articles

Background: Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson’s disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs).

Objective: At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients.

Methods: The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) …

A Review Of Community Aging In Place Programs To Minimize Social Isolation In Older Adults, Heather J. Goodwater, Joanna M. Yutrzenka

Occupational Therapy Capstones

The aging baby boomer population calls for new solutions to enable older Americans to age in place in their communities of choice. Nine out of ten adults age 50 and older prefer to remain in their homes indefinitely as they age, or as long as they possibly can (Gonyea, & Burnes, 2013). However, program funding that supports aging in place does not come close to keeping pace with the rapid growth of the 65 and older population (American Institutes for Research, 2016). There are a limited number of programs in place to address socialization in community-dwelling older adults. The prevalence …

Shortening The Duration Of Antimicrobial Therapy In Uncomplicated Skin And Soft Tissue Infections, Alicia Daggett, Brandi Missel

Posters

No abstract provided.

Ellen White, Health, And The Third Angel’S Message: Part 3– Recognizing Environmental Hazards And Minimizing Their Impact, Warren A. Shipton

Journal of the Adventist Theological Society

Satan’s rebellion in heaven centered around his dissatisfaction with the principles and organization of the heavenly domain (Isa 14:12–14). In his first recorded interchange on earth after his expulsion from heaven, Satan inferred there was a moral defect in God’s character in the words “You will not surely die” (Gen 3:4) in response to Eve’s repetition of God’s advice that death would follow disobedience (v. 3). Eve was deceived by his persuasive reasoning. After Adam’s choice to follow Eve in rebellion, God’s portrait (image) commenced to be erased in humanity through disbelief and disobedience. This process has continued with the …

Niche Modeling For The Genus Pogona (Squamata: Agamidae) In Australia: Predicting Past (Late Quaternary) And Future (2070) Areas Of Suitable Habitat, Julie E. Rej, T. Andrew Joyner

ETSU Faculty Works

Background: As the climate warms, many species of reptiles are at risk of habitat loss and ultimately extinction. Locations of suitable habitat in the past, present, and future were modeled for several lizard species using MaxEnt, incorporating climatic variables related to temperature and precipitation. In this study, we predict where there is currently suitable habitat for the genus Pogona and potential shifts in habitat suitability in the past and future. Methods: Georeferenced occurrence records were obtained from the Global Biodiversity Information Facility, climate variables (describing temperature and precipitation) were obtained from WorldClim, and a vegetation index was obtained from AVHRR …

Gene Editing: Combating Malaria With Crispr/Cas9, Christine Craddock

The Synapse: Intercollegiate science magazine

No abstract provided.

Interactions Between Two Key Amphibian Defenses To Batrachochytrium Dendrobatidis In Panamanian Glass Frogs (Espadarana Prosoblepon), Andi Levorse

Honors Theses

Research on the amphibian pathogen Batrachochytrium dendrobatidis (Bd), the causative agent of the lethal disease chytridiomycosis, has advanced from assessments of pathogenicity and species susceptibility to more specialized questions concerning the complex interactions between the pathogen, species-specific immune responses, and the environment. Our work examines the potential for interactions between the two most important innate immune defenses of frogs against Bd: secretions of antimicrobial peptides and communities of commensal cutaneous bacteria. While both defenses have been studied individually, little data are available to examine interactions between these defenses. We conducted our study with field captured Panamanian glass frogs …

Community Structure Of The Microbiome Of Ixodes Scapularis In Relation To Sex, Stage, Lineage, And Geography, Christopher Lee Clark

Honors Theses

This study sought to fill these gaps of knowledge ticks as a model species. Based on the known information on the microbiome of vectors, and ticks more specifically, I sought to answer two prominent questions: are there relationships between the microbiome of individual ticks and do ticks from different sexes or life stages have variance in their microbiomes? In reference to my first question, I hypothesized that ticks coming from the same lineage, being the males, 7 Community Structure of the Microbiome of Ixodes scapularis females, and resulting eggs, would have a more similar microbiome to each other than to …

European Starlings, George M. Linz, Ron J. Johnson, James Thiele

United States Department of Agriculture Wildlife Services: Staff Publications

European starlings (Sturnus vulgaris, Sturnidae) are native to Europe, southwest Asia, and North Africa and have successfully established populations on every continent but Antarctica (Rollins et al. 2009). In 1890 and 1891, a member of the American Acclimatization Society, Eugene Scheiffelin, released 100 starlings into New York City’s Central Park, with the objective of introducing all the birds mentioned in the plays of William Shakespeare to North America (Cabe 1993). He was successful, as 16 pairs survived and reproduced prolifically. Starlings reached the Mississippi River in 1928 and were observed on the West Coast in 1942. In a …

Factors Affecting Completion Of Childhood Immunization In North West Nigeria, Sule Abdullahi

Walden Dissertations and Doctoral Studies

North West Nigeria has the lowest vaccination rate of the geopolitical regions of the country. The purpose of this cross-sectional study was to examine associations between the parents'/caregivers' biological, cultural, and socioeconomic factors and the completion or noncompletion of routine immunization schedules. Andersen's behavioral model provided the framework for the study. Data were obtained from the 2013 National Demographic Health Survey. Descriptive statistics were calculated for all variables. Chi-square tests were used for categorical predictor variables, simple logistic regression models were used for the age variable, and multiple linear regression models were used for the biological, cultural, and socioeconomic variables …

Method Development And Pharmacokinetic Study Of Jy08, A Dual Opioid-Npff Receptor Ligand, Sydney Harrison

Honors Theses

Within the United States and worldwide, a rapidly developing public health crisis is at hand due to the abuse of opioids. With high percentages of Americans experiencing both acute and chronic pain and limited treatment routes, opioid analgesics are highly prescribed in clinical practice. These drugs act on central nervous system to activate opioid receptors in regions of the brain regulating pain and reward. However, these compounds are associated with many unwanted adverse effects including tolerance, dependence, hyperalgesia, and addiction. Thus, there is a need to for the development of new drug candidates that can serve as analgesics for long-term …

The Lived Experiences Of Managing Uncertainty In Chronic Illness, Amanda Brown

Walden Dissertations and Doctoral Studies

Chronic illness is an increasing concern in the United States as the CDC reports that about 50% of adults have at least 1 chronic illness. When individuals must adjust to chronic illness they may experience uncertainty regarding the illness, prognosis, and symptoms. The purpose of this qualitative, phenomenological study was to explore the lived experiences of individuals living with uncertainty in chronic illnesses. A Merle Mishel's uncertainty in illness theory was the framework used to explore the lives of individuals diagnosed and living with chronic illness. In-depth interviews were conducted with 8 individuals who have chronic disease; data were audio-recorded …

Perceived Cardiovascular Risk Among West Africa Immigrants In Dekalb County, Georgia, Oluwayomi Fabayo

Walden Dissertations and Doctoral Studies

West African immigrants appear to carry a heavier burden of hypertensive heart disease than the native-born African Americans in the United States. In this study, I used the socioecological model theory as a guide to examine the association between perceived stress, length of stay in United States, smoking status, housing conditions, and the risk of hypertensive heart disease among West African immigrants, ages 18 - 54 years in DeKalb County, Georgia. In this quantitative, cross-sectional design, self-reported data were collected from a sample of West African immigrant (N=107) in the DeKalb County of Georgia, using a demographic data/screening sheet and …

Analysis Of Latent Tuberculosis Infection Treatment Adherence In An Inner-City Clinic, Yvonne Washington-Turay

Walden Dissertations and Doctoral Studies

More than 10 million people in the United States are known to have latent tuberculosis infection (LTBI), and more than 300,000 begin treatment for LTBI annually. However, many fail to adhere to therapy for numerous reasons. The purpose of this project was to evaluate the impact of a new guideline, Targeted Tuberculin Testing and the Treatment of Latent Tuberculosis, at inner-city tuberculosis (TB) control clinic in the United States. The practice-focused question for the project asked if the implementation of the clinical guideline using a shorter regimen improved LTBI treatment adherence. The health beliefs model was the framework used to …

County Health Leadership And Readiness For Noncommunicable Disease Services, Paul Wekesa Agunga

Walden Dissertations and Doctoral Studies

Premature mortality resulting from the growing global burden of noncommunicable diseases (NCDs) is a contemporary development challenge. Low-income and lower-middle-income countries are disproportionately affected, with the poorest in society considered the most vulnerable. A paucity of literature exists on how leadership practices at the implementation level relate to ensuring readiness for NCD services. The purpose of this study was to investigate whether any relationship exists between leadership practices at the county level and readiness for NCD services in Kenya. Path-goal and adaptive leadership theories were used to guide this quantitative correlational study, using secondary data from a 2013 Service Availability …

Health Promoting Behaviors Of Young Adults With Chronic Lyme Disease, Patricia D. Bolivar

Walden Dissertations and Doctoral Studies

Lyme disease is the most prevalent arthropod-borne (tick) disease in North America. The disease is more prevalent in some Eastern and Central states than in Western states. The general problem is that, in southern California especially in Los Angeles County, both patients and practitioners fail to recognize the disease, resulting in misdiagnosis and delayed treatment. Consequently, the patient may develop the long-term, chronic Lyme disease (CLD). The purpose of this phenomenological study was to explore the impact of CLD on the health-promoting behaviors of ethnically diverse young adults from similar educational and socioeconomic backgrounds based on their lived experiences. The …

Perceptions Of Healthcare Workers Toward Influenza Vaccination, Amos Adedokun

Walden Dissertations and Doctoral Studies

Even though influenza vaccinations were provided free to all healthcare workers in the United States, healthcare workers were not 100% compliant. The non-compliance with influenza vaccinations may expose their patients, their families, and the public at large to a high-risk source of influenza infection. This study's research questions included how registered nurses perceived influenza and influenza vaccination; registered nurses' self-reported incidents with influenza vaccination; and factors that contributed to registered nurses' non-compliance with influenza vaccination. Guided by the theory of reasoned action and the theory of planned behavior, the purpose of this qualitative study was to determine the factors that …

Variables That Impact Incidence Of Diarrhea Amongst Under-Five In Uganda, Anne Ngonde Muli

Walden Dissertations and Doctoral Studies

Diarrhea in children remains a major public health problem in Uganda and other countries in the region and acts as one of the leading contributors to child mortality. Most of the risk factors for diarrhea in children are preventable. This study, guided by the socioecological model, was conducted to investigate the association between the occurrence of diarrhea in children and length of breastfeeding, coinfection with acute respiratory infection (ARI), and vaccination status of the child. These variables were identified in the literature as risk factors for diarrhea that had not been investigated in Uganda. The source of the data for …

Waste Management Minimization Strategies In Hospitals, Andrea L. Clark

Walden Dissertations and Doctoral Studies

During the delivery of healthcare services, hospital employees use enormous amounts of water, energy, and nonbiodegradable carcinogenic plastics. In the U.S., hospital staff generate an average of over 7,000 tons of waste per day at an average cost of $0.28 per pound for the disposal of regulated medical trash, which if efficiently managed or reduced, could result in substantial cost savings. Using the organizational learning and the transaction cost economics theories as the conceptual frameworks, the purpose of this qualitative case study was to explore strategies healthcare leaders used to minimize their waste management operational costs. Data were collected using …

The County-Level Impact Of Telemedicine: A Difference-In-Differences Analysis Of The University Of Mississippi Medical Center's Telemedicine Initiatives, Megan Elise Mcleod

Honors Theses

Mississippi has the fewest active physicians per capita of any state, consistently struggles with high rates of acute and chronic illness, and over half of its residents live in rural areas lacking specialty medical care. In an effort to bridge the state's geographical gap in access to healthcare, the University of Mississippi Medical Center (UMMC) has introduced telemedicine. This study conducts an analysis of some of the societal benefits of UMMC's telemedicine initiatives using a difference-in-differences identification strategy. This model attempts to obtain the county-level causal effects of implementing telemedicine by evaluating the resulting changes in length of life, quality …

Improving The Lifestyle Of Andrews Korean Seventh-Day Adventist Church Members, Myung Do Park

Doctor of Ministry Projects

Problem

The Andrews Korean Seventh-day Adventist church in Berrien Springs, Michigan has holistic lifestyle problems that are on the rise. Church members are experiencing health issues such as cancer, high blood pressure, diabetes, osteoporosis, and insomnia. In observing dietary patterns, it was noticed that some of our members do not bother to ascertain the content of the food being eaten. Other members have express the desire to learn about a healthy lifestyle. Purposeful attention to this need of the church is necessary. As a church community comprised of mostly pastors, university students and their families it is time to advocate …

Twenty Years Of Spayvac® Research: Potential Implications For Regulating Feral Horse And Burro Populations In The United States, Ursula S. Bechert, Mark A. Fraker

Human–Wildlife Interactions

There are currently >75,000 feral horses (Equus ferus caballus) and burros (E. asinus ) on U.S. public lands, yet the Appropriate Management Level (AML) is set at just under 27,000. Wildlife managers, conservation biologists, and livestock ranchers are concerned about the impacts that these free-ranging horses have on shared rangelands. Immunocontraceptive vaccines may have the greatest potential to regulate horse population numbers once AML is reached; however, the vaccine must have multi-year efficacy to be both technically feasible and cost-effective. Immunocontraception based on porcine zona pellucida (PZP)-specific antigens is highly tissue-specific, targeting the ova, and blocking sperm binding through antibody …

Effects Of Ginger Supplementation On Inflammation In Individuals, Sara Kashlan, Brenda Rodriguez, Monique Vuong

Loma Linda University Research Reports

Background. Ginger is a widely used ingredient in Southeast Asian countries and has gained increasing popularity in the Western diet due to its purported health benefits. Ginger has high antioxidant power because of its rich phytochemistry profile that contributes to its anti- inflammatory properties. While there have been animal studies, the research of ginger’s effects in humans is limited.

Objective. We sought to understand ginger’s effects on commonly assayed inflammatory biomarkers—C-Reactive Protein (CRP), Interleukin-6 (IL-6), and Tumor Necrosis Factor-Alpha (TNF- α)—in individuals with varying levels of physical activity. We propose that ginger may lower levels of these biomarkers …

Environmental Health Program Performance And Its Relationship With Environment-Related Disease In Florida, Justin A. Gerding, Nailya O. Delellis, Antonio J. Neri, Timothy A. Dignam

Florida Public Health Review

This study used a unique approach to examine Florida county health department environmental health (EH) program performance of the 10 Essential Environmental Public Health Services (EEPHS) and its relationship with environment- related disease, described by enteric disease rates. Correlation analysis tested the association between performance of each EEPHS and five different enteric disease rates, while multivariate regression analysis further examined the relationships while considering program organizational characteristics as potential confounders. Correlation analysesrevealed cryptosporidiosis was associated with EEPHS 2 diagnose (Τb = .195, p = .027) and EEPHS 8 workforce (Τb= .234, p = .006), and salmonellosis with EEPHS 4 mobilize …

The Encyclopedia Of North American Drosophilids Volume 1: Drosophilids Of The Midwest And Northeast, Thomas Werner, Tessa Steenwinkel, John Jaenike

Open Access Books

The Encyclopedia of North American Drosophilids: Volume 1: Drosophilids of the Midwest and Northeast provides an introduction to the flies of the family Drosophilidae of the Midwest and Northeast of the United States, as well as nearby regions in Canada. The book strives to facilitate identification of most of the drosophilid species in this region and provides remarks on interesting aspects of their biology and suggestions for future research on them. The book is intended for researchers, teachers, and students wishing to discover the diversity of these flies.

Version 4 is a major update that covers new species and includes …