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P16-Ki67-Hmb45 Immunohistochemical Profiling May Help Discriminate Between Spitzoid Melanoma And Atypical Spitz Nevi, Robert E. Garola, Vivekanand Singh

Posters

Background

When Spitz nevi have increased vertical thickness (>1.5 MM), show ulceration and deep seated mitosis, the differential diagnostic considerations of atypical Spitz nevus (ASN) or a Spitzoid melanoma (SM) enter into consideration. While expert consultation from a dermatopathologist is most often sought to resolve the differential diagnosis, it could be expensive and time consuming. Recently, the use of molecular genetic testing has also been advocated in the work group up of atypical melanocytic proliferations. On the contrary, immunohistochemistry is a more routinely used technique in most pathology centers may be more simple to apply. A single immunohistochemical marker …

Economic Evaluation For Health Advocacy And Informed Policy / Maznah Dahlui, Dahlui Maznah

Archival Material (2010s)

Globally, economic evaluation is gaining prominence as a potential tool for advocacy in health care programmes. Economic evaluations can inform decisions concerning the efficiency and allocation of resources to implementation strategies which are explicitly designed to inform care providers and patients about the best available research evidence and to enhance its use in their practices. These strategies are increasingly popular in health care, especially in light of growing concerns about quality of care and limits on resources. However, such concerns have hardly driven health authorities and other decision-makers to spend on some form of economic evaluation in their assessments of …

Vaccine For A Strain Of Avian Influenza To Be Tested In Clinical Trial At Uab, Alicia Rohan

Browse All News

No abstract provided.

Molecular Detection Of Multidrug-Resistant Mycobacterium Tuberculosis In Al Muthanna Province, Haider H. Mitab

Muthanna Medical Journal

Multidrug-resistant tuberculosis (MDR-TB) is a global problem that many countries are challenged with. Rapid and accurate detection of MDR-TB is critical for appropriate treatment and controlling of TB. The aims is detection of multidrug-resistant Tuberculosis from cultured samples by using Polymerase Chain Reaction. A total of 30 M. tuberculosis isolates from cases with diagnosed TB by GeneXpert, AFB and Culture on L. J media after incubation period from 3-8 weeks, DNA extraction from bacteria colonies. Resistant isolates were tested for characterization of mutations in the rpoB, KatG InhA1 and IhA2 genes by Real Time PCR. The results of the real …

The Idea Of A “Fleet In Being” In Historical Perspective, John B. Hattendorf

Naval War College Review

The phrase “fleet in being” is one of those troublesome terms that naval historians and strategists have tended to use in a range of different meanings. The term first appeared in reference to the naval battle off Beachy Head in 1690, during the Nine Years’ War, as part of an excuse that Admiral Arthur Herbert, first Earl of Torrington, used to explain his reluctance to engage the French fleet in that battle.

Characterizing The Phylogenetic Specialism-Generalism Spectrum Of Mammal Parasites, A. W. Park, M. J. Farrell, J. P. Schmidt, S. Huang, T. A. Dallas, P. Pappalardo, J. M. Drake, P. R. Stephens, R. Poulin, C. L. Nunn, T. J. Davies

Faculty Publications

© 2018 The Author(s) Published by the Royal Society. All rights reserved. The distribution of parasites across mammalian hosts is complex and represents a differential ability or opportunity to infect different host species. Here, we take a macroecological approach to investigate factors influencing why some parasites show a tendency to infect species widely distributed in the host phylogeny (phylogenetic generalism) while others infect only closely related hosts. Using a database on over 1400 parasite species that have been documented to infect up to 69 terrestrialmammal host species,we characterize the phylogenetic generalism of parasites using standard effect sizes for three metrics: …

Vaccination In Rheumatoid Arthritis Patients – Case Report, Jenny Weyers

Nursing Capstones

No abstract provided.

Aeds In Faith-Based Communities, Dana Walker

Nursing Education Research Conference (NERC)

Participants can expect to see how to collaborate with community leaders to impact safety concerns of the community. This project focuses on pulling available resources to improve compliance with AED maintenance in the community setting.

Taxonomy Based On Science Is Necessary For Global Conservation [Formal Comment], Scott A. Thomson, Richard L. Pyle, Scott Monks, Neal L. Evenhuis, Ronald H. Pine, Luis A. Ruedas, Jorge A. Salazar-Bravo, Robert M. Timm, Douglas Yanega, 163 Other Co-Authors

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Taxonomy is a scientific discipline that has provided the universal naming and classification system of biodiversity for centuries and continues effectively to accommodate new knowledge. A recent publication by Garnett and Christidis expressed concerns regarding the difficulty that taxonomic changes represent for conservation efforts and proposed the establishment of a system to govern taxonomic changes. Their proposal to “restrict the freedom of taxonomic action” through governing subcommittees that would “review taxonomic papers for compliance” and their assertion that “the scientific community's failure to govern taxonomy threatens the effectiveness of global efforts to halt biodiversity loss, damages the credibility of science, …

Synthesis And Biological Evaluation Of 8-Quinolinamines And Their Amino Acid Conjugates As Broad-Spectrum Anti-Infectives, Meenakshi Jain, Chandrasekhar Reddy, Moumita Halder, Savita Singh, Randheer Kumar, Sagar Gajbe Wasudeo, Prati Pal Singh, Shabana I. Khan, Melissa R. Jacob, Babu L. Tekwani, Rahul Jain

Faculty and Student Publications (Open Access)

No abstract provided.

A Synopsis Of The Civil Rights Struggle In Tampa And The Role Of The Tampa Branch Of The National Association For The Advancement Of Colored People, Robert W. Saunders

Sunland Tribune

No abstract provided.

Host Species, And Not Environment, Predicts Variation In Blood Parasite Prevalence, Distribution, And Diversity Along A Humidity Gradient In Northern South America, Robert Ricklefs, Paulo Pulgarín‐R, Juan Gómez

Biology Department Faculty Works

Environmental factors strongly influence the ecology and evolution of vector‐borne infectious diseases. However, our understanding of the influence of climatic variation on host–parasite interactions in tropical systems is rudimentary. We studied five species of birds and their haemosporidian parasites (Plasmodium and Haemoproteus) at 16 sampling sites to understand how environmental heterogeneity influences patterns of parasite prevalence, distribution, and diversity across a marked gradient in water availability in northern South America. We used molecular methods to screen for parasite infections and to identify parasite lineages. To characterize spatial heterogeneity in water availability, we used weather‐station and remotely sensed climate data. We …

Perspective Suggests Treatment As Prevention Can Help Stop The Spread Of Hiv, Staff

Browse All News

No abstract provided.

Data And Statistical Methods To Analyze The Human Microbiome, Levi Waldron

Publications and Research

The Waldron lab for computational biostatistics bridges the areas of cancer genomics and microbiome studies for public health, developing methods to exploit publicly available data resources and to integrate-omics studies.

Disease Ontology: Improving And Unifying Disease Annotations Across Species., Susan M. Bello, Mary Shimoyama, Elvira Mitraka, Stanley J F Laulederkind, Cynthia Smith, Janan T. Eppig, Lynn M Schriml

Faculty Research 2018

Model organisms are vital to uncovering the mechanisms of human disease and developing new therapeutic tools. Researchers collecting and integrating relevant model organism and/or human data often apply disparate terminologies (vocabularies and ontologies), making comparisons and inferences difficult. A unified disease ontology is required that connects data annotated using diverse disease terminologies, and in which the terminology relationships are continuously maintained. The Mouse Genome Database (MGD, http://www.informatics.jax.org), Rat Genome Database (RGD, http://rgd.mcw.edu) and Disease Ontology (DO, http://www.disease-ontology.org) projects are collaborating to augment DO, aligning and incorporating disease terms used by MGD and RGD, and improving DO as a tool for …

Winter Feeding Of Elk In The Greater Yellowstone Ecosystem And Its Effects On Disease Dynamics, Gavin C. Cotterill, Paul C. Cross, Erik K. Cole, Rebecca K. Fuda, Jared D. Rogerson, Brandon M. Scurlock, Johan T. Du Toit

Wildland Resources Faculty Publications

Providing food to wildlife during periods when natural food is limited results in aggregations that may facilitate disease transmission. This is exemplified in western Wyoming where institutional feeding over the past century has aimed to mitigate wildlife–livestock conflict and minimize winter mortality of elk (Cervus canadensis). Here we review research across 23 winter feedgrounds where the most studied disease is brucellosis, caused by the bacterium Brucella abortus. Traditional veterinary practices (vaccination, test-and-slaughter) have thus far been unable to control this disease in elk, which can spill over to cattle. Current disease-reduction efforts are being guided by ecological …

Procedure For Cannulating A Dialysis Access: Using The Assure Model And Gagne's Events Of Instructions, Pandora Goode

Nursing Education Research Conference (NERC)

For learners to move from a lower level order of thinking to a higher-level order of thinking successfully, learners must follow an orderly systematic approach. The ASSURE model is a six-step instructional model that incorporates Roberts Gagne's 9 Events of instruction when presenting or delivering any form of educational content.

Flames And Frogs – The Impact Of Environmental Disturbances On Host-Parasite Dynamics, Nicole Ortega

USF Tampa Graduate Theses and Dissertations

The successful completion of this work is dedicated first to my grandparents for having always shown their unwavering love and encouragement in my journeys (most of which they kindly and politely only pretended to understand) and for having also served as life-long role models who upheld an unparalleled work ethic. To many whom I consider to be my chosen family, especially Ann Williams and Brittany Sears, who kept me laughing, but more importantly, kept my crazy train from derailing during these tumultuous years. To Wayne Price and Tom Jackman, who fostered the success of my career and are the epitome …

What Makes Super‐Aged Nations Happier? Exploring Critical Factors Of Happiness Among Middle‐Aged Men And Women In Japan, Yoko Moriyama, Nanako Tamiya, Nobuyuki Kawachi, Maya Miyairi

Kinesiology and Health Science Faculty Publications

This study aimed to examine multiple factors associated with happiness from the perspective of gender difference among a middle‐aged Japanese population. A total of 865 participants (male = 344, female = 521) aged 40–64 years were divided into two groups (high and low) by their self‐reported level of happiness. Logistic regression analysis by gender was carried out. In men, high levels of happiness were significantly correlated with living with spouse, occupation, enough sleep, leading a normal life, and regular checkups; while low levels of happiness were significantly correlated with smoking and having two or more diseases. In women, low levels …

Week Of March 12, 2018, New York Medical College

InTouch

• New Student-Run Medical Research Seminar Series Exceeds Expectations
• NYMed Talks 2018 Set to Focus on the Intersection of Medicine and Society

Factors Affecting The Parasitism Of Gregarine Species In Grasshoppers In Western Nebraska, Alexandra Creigh, Kristin Mclarty, Scott Lyell Gardner

Honors Program: Senior Projects (Public)

We conducted a survey of the species of parasites found in grasshoppers around the area of Dunwoody’s Pond to investigate whether there were any species specific parasitic relationships occurring there. We collected grasshoppers from several areas around Dunwoody’s Pond totaling 15 species including Melanoplus bivittatus (Say 1825) , Melanoplus sanguinipes (Fabricius, 1798) , Melanoplus differentialis (Thomas 1865), and Melanoplus femurrubrum (De Geer 1773), along with others (Seymour et al., 2009) and compared the parasites found in them. This study is similar to one conducted in South America by Lloyd in 1951, and we hoped to find connections between species to …

Loop-Mediated Isothermal Amplification Methods For Diagnosis Of Bacterial Meningitis, Mitsuko Seki, Paul E. Kilgore, Eun Jin Kim, Makoto Ohnishi, Satoshi Hayakawa, Dong Wook Kim

Department of Pharmacy Practice

The rapid, accurate, and efficient identification of an infectious disease is critical to ensure timely clinical treatment and prevention in public health settings. In 2015, meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis was responsible for 379,200 (range: 322,700–444,700) deaths. Clinical features alone cannot determine whether bacterial meningitis is present; an analysis of cerebrospinal fluid (CSF) is essential. Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification method offering an alternative to polymerase chain reaction (PCR). LAMP-based assays for detection of three leading bacteria in CSF for diagnosis of meningitis have been established. The typing assays …

Synthesis Of Unnatural Sulfatides And Examination Of Their Role In Immunomodulation And Synthesis Of Palmostatin M-Derived Probes, Kevin Luvaga

Doctoral Dissertations

The two main foci herein are the preparation of sulfatides that activate a subset of type II natural killer T (NKT) cells and the synthesis and exploitation of the reactivity of unusual strained heterocycles. Chapter 1 describes the synthesis of two unnatural sulfatides. The preparation of one of these, an a-sulfatide, was motivated by the need to probe the effect of a potential a-linked sulfatide impurity in a previously synthesized b-sulfatide which had been shown to stimulate higher than expected secretion of both IFN-g and IL-4. The synthesis of the b-sulfatide was motivated by the fact that a related plakoside …

Career Corner: Quidel Seeks Product Development Manufacturing Associates, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Calnexin Is Necessary For T Cell Transmigration Into The Central Nervous System, Amber M. Paul, Joanna Jung, Paul Eggleton, Alison Robinson, Jessica Wang, Nick Gutowski

Publications

In multiple sclerosis (MS), a demyelinating inflammatory disease of the CNS, and its animal model (experimental autoimmune encephalomyelitis; EAE), circulating immune cells gain access to the CNS across the blood-brain barrier to cause inflammation, myelin destruction, and neuronal damage. Here, we discovered that calnexin, an ER chaperone, is highly abundant in human brain endothelial cells of MS patients. Conversely, mice lacking calnexin exhibited resistance to EAE induction, no evidence of immune cell infiltration into the CNS, and no induction of inflammation markers within the CNS. Furthermore, calnexin deficiency in mice did not alter the development or function of the immune …

Partnership Between Islam And Palliative Care At Swedish Health Services, Hodo Mohamud, Renee Rassilyer-Bomers, Samantha Bohn, Greg Malone, Hilaire Thompson (Faculty Capstone Project Committee Chair), Eeeseung Byun (Committee Member), Margaret Heitkemper (Committee Member)

Articles, Abstracts, and Reports

The spiritual practice of Islam is considered one of the three major monotheistic religions. Islam is the second largest religion in the world with 1.6 billion followers; about 3.5 million of those live in the U.S.1 The number of Muslims in the U.S. is projected to double by 2030.1 Additionally, the number of adults age 65 and older in the U.S. is projected to double from 46 million today to over 98 million by 2060.2 As the U.S. population ages, many healthcare workers are often too overwhelmed to handle the varying and intricate social, economic, familial, spiritual, and cultural needs …

“Capgras” Delusions Involving Belongings, Not People, And Evolving Visual Hallucinations Associated With Occipital Lobe Seizures, Brandon Lilly, Erika Maynard, Kelly Melvin, Suzanne Holroyd

Psychiatry

Capgras syndrome is characterized by the delusional belief that a familiar person has been replaced by a visually similar imposter or replica. Rarely, the delusional focus may be objects rather than people. Numerous etiologies have been described for Capgras to include seizures. Similarly, visual hallucinations, both simple and complex, can occur secondary to seizure activity.We present, to our knowledge, the first reported case of visual hallucinations and Capgras delusions for objects that developed secondary to new onset occipital lobe epilepsy.We then discuss the possible underlying neurologic mechanisms responsible for the symptomatology.

Whalesong 2018-03-07, N/A N/A

Whalesong

No abstract provided.

Effect Of Mobile Phone Text Message Reminders On Routine Immunization Uptake In Pakistan: Randomized Controlled Trial, Abdul Momin Kazi, Murtaza Ali, Khurram Zubair, Hussain Kalimuddin, Abdul Nafey Kazi, Saleem Perwaiz Iqbal, Jean-Paul Collet, Syed Asad Ali

Department of Paediatrics and Child Health

Background: Improved routine immunization (RI) coverage is recommended as the priority public health strategy to decrease vaccine-preventable diseases and eradicate polio in Pakistan and worldwide.
Objective: The objective of this study was to ascertain whether customized, automated, one-way text messaging (short message service, SMS) reminders delivered to caregivers via mobile phones when a child is due for an RI visit can improve vaccination uptake and timelines in Pakistan.
Methods: This was a randomized controlled trial, conducted in an urban squatter settlement area of Karachi, Pakistan. Infants less than 2 weeks of age with at least one family member who had …

March 6, 2018 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.