Digital Commons Network^™

A Real World Experience Of The Fast-Ed Based Pre-Hospital Stroke Triage System To Detect Large Vessel Occlusions, Ned Shashoua, Amy Starosciak, Jayme Strauss, Felipe De Los Rios La Rosa

All Publications

No abstract provided.

An Alternative To Implanting Loop Recorders In A Hospital, Marie Paule Lafontant, Valerie Smith, Nohemi Sadule Rios, Marsha Lambert

All Publications

No abstract provided.

Coloquio: Pro-Social Games For Healthy Social Interaction, Mintesinot T. Gebre

Theses

This study was conducted to address the unhealthy social and emotional development of children today as they are exposed to the adverse effects technology dominant environment. The extent of interference of screen interaction in today’s group activities at home, hinders opportunities for families to interact with one another. Surveys and tests were conducted for the purpose of finding where the undesired behaviors and habits formed by screen interaction become very pervasive. And the design solution proposes a pro-social activity that makes use of cognitive abilities to allow social activities and conversations to happen in parallel.

Sensitivity Analyses Of Electric Vehicle Life Cycle Impacts Based On Consumer Behaviors., Zaid Thanawala

Theses

Electric vehicles (EVs) are being promoted as a viable vehicle technology to mitigate the greenhouse gas emissions associated with conventional vehicles. Previous studies have shown that the use phase of the EVs is the main contributor to EV life cycle environmental impacts. Use phase impacts depend on multiple factors such as the type and amount of electricity used to charge the batteries, driving behavior, and life span of the battery.

Comprehensive life cycle assessment (LCA) studies exist on the impacts of electric vehicle. However, most studies assume no variability in user behavior. This variability could play a significant role in …

Patriarchal Ecocide: An Ecofeminist Reading Of Rahul Varma's Bhopal And Henrik Ibsen's An Enemy Of The People, Rania M Rafik Khalil

English Language and Literature

Ecofeminism is a movement that sees a connection between the exploitation of the natural world and the subordination of women. This concept of ecology and feminism conceptualized by Simone de Beauvoir (1952) and later refined by Francoise d’Eaubonne in 1974 has greened artistic values across disciplines, it is however perceived to be found only sparsely in drama. Una Chaudhuri (1994) and Theresa J. May (2005) argue that theatre is both “immediate and communal” (May 85) with a wealth of productions that “awaken ecological sensibilities” (85) and contest “industrialisation’s animus against nature” (24). Within this context, Henrik Ibsen’s An Enemy of …

Tennessee Farm Bureau News - November 2018, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

Basics Of Compounding: Vehicles For Compounded Oral Liquid Medications: A Review, Kara Cutaia, Lipika Chablani, Fang Zhao

Pharmacy Faculty/Staff Publications

Compounded oral liquid medications play an important role in addressing the unmet needs of special patient populations, including pediatric, geriatric, and tube fed patients. The use of manufactured vehicles can streamline the compounding activities for pharmacists. In recent years, there is an increase in the availability of manufactured vehicles with various promotional features. This article uses the general formulation principles as a guide to compare and contrast the manufactured vehicles regarding their physicochemical properties, presence of preservatives and dyes, organoleptic properties, and ease of use. A summary table is provided as a reference tool to assist pharmacists in selecting the …

Successful Negotiations: A Phenomenological Study Of The Lived Experiences Of Superintendents Who Successfully Negotiate Teacher Contracts, Kelly A. Theurer

Doctoral Dissertations and Projects

New York State has a long history related to teachers’ unions. Superintendents are often the main players for school districts when negotiating teachers’ contracts. While much has been researched about negotiations, there is a gap in the literature in relation to the motivating factors of superintendents to successfully negotiate teachers’ contracts. The purpose of this transcendental phenomenological study was to describe the lived experiences of school superintendents who have successfully negotiated teachers’ contracts within suburban areas of New York State. The central research question was: What are the lived experiences of school superintendents who have successfully negotiated teachers’ contracts in …

A Correlational Study Of Teacher Burnout In Elementary Schools In Georgia, Kimberly A. Hancock

Doctoral Dissertations and Projects

Educational research has identified the importance of understanding the relationship between teacher burnout and teacher self-efficacy. Previous studies examined the relationship of teacher burnout to teacher self-efficacy, more focused research is needed in order to understand the relationship in regards to teaching in Title I and Title I Focus schools. This quantitative correlational study examined the relationship between teacher burnout and self-efficacy for teachers working in Title I and Title I Focus schools. This study also investigated which factors predicted burnout. A convenience sample of 87 teachers from four urban Georgia elementary Title I and Title I Focus schools with …

Bs News November/December

Building Services Engineering

No abstract provided.

Knowledge, Attitudes, And Practice Behavior Of Dental Hygienists Regarding The Impact Of Systemic Diseases On Oral Health, Asma’A A. Faden, Anas B. Alsalhani, Majdy M. Idrees, Mohammed A. Alshehri, Mohammad Z. Nassani, Omar B. Kujan

Saudi Medical Journal

Objectives: To assess the knowledge levels of dental hygienists in Saudi Arabia regarding the association between systemic and oral disease in addition to evaluating their attitude about integrating this knowledge into clinical practice. Methods: This was a cross-sectional survey using a questionnaire of 102 items among 192 randomly selected dental hygienists practicing in Riyadh, Saudi Arabia by individual interview. The research tool was pilot tested among 12 dental hygienists (8 females and 4 males) to obtain feedback about clarity and objectivity. Results: The response rate was 83%, and the majority of respondents were female (77.5%). The respondents’ knowledge about the …

Breastfeeding Self Efficacy Among Pregnant Women In Saudi Arabia, Reham M. Khresheh, Nagwa M. Ahmed

Saudi Medical Journal

Objectives: To examine the association between prenatal breastfeeding self-efficacy among Saudi pregnant women and type of feeding at 4 weeks post partum, and also to examine the association of maternal socio-demographic variables with the breastfeeding self-efficacy levels of Saudi pregnant women. Methods: A cross-sectional design has been applied in the study by recruiting 101 pregnant women from the General Hospital, Umluj, Kingdom of Saudi Arabia. The prenatal breastfeeding self-efficacy scale was used to measure self-efficacy for breastfeeding during pregnancy. Descriptive statistics, Chi-square, Pearson correlation coefficient were used for statistical purposes. A p -value ≤0.05 was considered significant. Results: The average …

Cesarean Sections. Associated Factors And Frequency At King Abdulaziz Medical City In The Central Region Of The Kingdom Of Saudi Arabia, Anwar E. Ahmed, Rouzait S. Mohammad

Saudi Medical Journal

Objectives: To study the associated factors for cesarean section (C-section) in a sample of pregnant women and to estimate its frequency at King Abdulaziz Medical City in Riyadh, Kingdom of Saudi Arabia (KAMC-R). Methods: We studied 364 pregnant women who attended the Gynecology and Obstetrics Clinic at KAMC-R between March and June 2017. Results: Our 3-month study had higher rates of C-sections: women with older maternal age; (adjusted risk ratio [aRR]=1.08, p =0.001), lack of education (aRR=1.39, p =0.022), no personal history of vaginal delivery (aRR=1.85, p =0.001), undergoing C-section due to medical indications (aRR=2.28, p =0.001), and willing to …

Oncology Nurses’ Knowledge, Practice, And Confidence Toward Chemotherapy-Induced Peripheral Neuropathy In Jordan, Nijmeh M. Al-Atiyyat, Almutazbillah Z. Banifawaz

Saudi Medical Journal

Objectives: To assess the knowledge, practice, and confidence of oncology nurses toward chemotherapy-induced peripheral neuropathy (CIPN) among patients with cancer in Jordan. Methods: Descriptive, and cross sectional study was conducted on a convenience sample of 148 Jordanian registered oncology nurses recruited from a Specialized Oncology Center in Jordan. Data collection took place in June, 2015. As a data collection tool, the assessment of oncology nurses’ knowledge and practice-revised questionnaire was used. Results: The mean CIPN knowledge score of 8.98/16 (SD=1.9) indicated that there were knowledge deficits regarding CIPN among Jordanian oncology nurses. Only 58.8% of the subjects indicated that CIPN …

Comment On: Growth Characteristics In Children With Congenital Adrenal Hyperplasia, Mahmood D. Al-Mendalawi

Saudi Medical Journal

No abstract provided.

Immune Therapy Generates Promising Results In Hard-To-Treat Ankylosing Spondylitis

Saudi Medical Journal

No abstract provided.

Weight Loss Linked To Lower Breast Cancer Risk For Postmenopausal Women

Saudi Medical Journal

No abstract provided.

Pool Of Mers Experts For Deployment Established By Who’S Regional Office For The Eastern Mediterranean

Saudi Medical Journal

No abstract provided.

Glasdegib In Combination With Cytarabine And Daunorubicin In Patients With Aml Or High-Risk Mds: Phase 2 Study Results, Jorge E Cortes, Mark A Schroeder, Et Al

Open Access Publications

Glasdegib is a Hedgehog pathway inhibitor. This ongoing, open-label, phase 2 study (NCT01546038) evaluated glasdegib plus cytarabine/daunorubicin in patients with untreated acute myeloid leukemia (AML) or high-risk myelodysplastic syndromes (MDS). Patients received glasdegib 100 mg orally, once daily in continuous 28-day cycles from day -3, with intravenous cytarabine 100 mg/m

Adapting Crowdsourced Clinical Cancer Curation In Civic To The Clingen Minimum Variant Level Data Community-Driven Standards, Arpad M Danos, Alex H Wagner, Kilannin Krysiak, Erica K Barnell, Joshua F Mcmichael, Susanna Kiwala, Adam C Coffman, Lynzey Kujan, Malachi Griffith, Obi L Griffith, Et Al

Open Access Publications

Harmonization of cancer variant representation, efficient communication, and free distribution of clinical variant-associated knowledge are central problems that arise with increased usage of clinical next-generation sequencing. The Clinical Genome Resource (ClinGen) Somatic Working Group (WG) developed a minimal variant level data (MVLD) representation of cancer variants, and has an ongoing collaboration with Clinical Interpretations of Variants in Cancer (CIViC), an open-source platform supporting crowdsourced and expert-moderated cancer variant curation. Harmonization between MVLD and CIViC variant formats was assessed by formal field-by-field analysis. Adjustments to the CIViC format were made to harmonize with MVLD and support ClinGen Somatic WG curation activities, …

Mouse Models Of Preterm Birth: Suggested Assessment And Reporting Guidelines, Ronald Mccarthy, Carmel Martin-Fairey, Dorothy K. Sojka, Erik D. Herzog, Emily S. Jungheim, Molly J. Stout, Justin C. Fay, Mala Mahendroo, Jeff Reese, Jennifer L. Herington, Erin J. Plosa, Elaine L. Shelton, Sarah K. England

Open Access Publications

Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences. To investigate the mechanisms leading to preterm birth so as to develop prevention strategies, researchers have developed numerous mouse models of preterm birth. However, the lack of standard definitions for preterm birth in mice limits our field's ability to compare models and make inferences about preterm birth in humans. In this review, we discuss numerous mouse preterm birth models, propose guidelines for experiments and reporting, and suggest markers that can be used to assess whether …

Teenage Exercise Is Associated With Earlier Symptom Onset In Dysferlinopathy: A Retrospective Cohort Study, Ursula R Moore, Matthew Harms, Alan Pestronk, Et Al

Open Access Publications

No abstract provided.

In This Issuereview Articleoriginal Articles

Saudi Medical Journal

No abstract provided.

Auragain™ And I-Gel® Laryngeal Masks In General Anesthesia For Laparoscopic Cholecystectomy: Performance Characteristics And Effects On Hemodynamics, Ulku Sabuncu, Hatice S. Kusderci, Mesut Oterkus, Ruslan Abdullayev, Asli Demir, Oznur Uludag, Sabri Ozdas, Mustafa Goksu

Saudi Medical Journal

Objectives: To evaluate and compare the performances of new types of supraglottic airway devices (SADs) with endotracheal intubation regarding their ease of insertions, perioperative complications, and effects on hemodynamic parameters and peak airway pressures in laparascopic cholecystectomy (LC). Methods: One hundred and fourteen patients with ASA 1-2 physical status scheduled for elective LC were recruited for this prospective randomized controlled trial. The study was completed between January 2016 and January 2017 in Adiyaman University Research and Educational Hospital, Adiyaman, Turkey. The patients were divided into AuraGain ™ (Ambu, Ballerup, Denmark) (n=38), i-Gel® (Intersurgical Ltd, UK) (n=35), and endotracheal tube (ETT) …

Venous Thromboembolism After Total Knee And Hip Arthroplasty: A Retrospective Study, Mosaad O. Almegren, Alhanouf A. Alhedaithy, Amal S. Alomri, Nouf F. Albawardy, Rawan S. Mesmar

Saudi Medical Journal

Objectives: To evaluate the incidence and risk factors of Venous thromboembolism (VTE) among total knee arthroplasty (TKA) and total hip arthroplasty (THA) patients following surgery. Methods: We conducted a retrospective review of electronic medical records of consecutive patients between January 2010 and January 2015 who underwent TKA or THA at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. Results: The incidence of symptomatic VTE was 1.9% (17 events, 95% CI: 1.1–2.8) in 756 patients who underwent 889 surgeries. All VTE cases developed before hospital discharge. Twelve (1.4%) patients developed pulmonary embolism, and 5 (0.6%) patients developed deep vein thrombosis. The …

Contraceptive Use As Limiters And Spacers Among Women Of Reproductive Age In Southwestern, Saudi Arabia, Mohammed A. Alsaleem, Shamsun N. Khalil, Aesha F. Siddiqui, Maha M. Alzahrani, Safar A. Alsaleem

Saudi Medical Journal

Objectives: To examine the prevalence, socioeconomic, and demographic determinants of contraceptive use among women of reproductive age residing in Abha, Kingdom of Saudi Arabia. Methods: The data of this study was collected through a cross sectional survey conducted on unmet need for family planning in Abha, Kingdom of Saudi Arabia, between March and May 2016. Three hundred and seventy-four married women were recruited from 6 primary health care centers by a consecutive sampling technique. Data was collected via an interviewer-administered questionnaire. Chi-square test was carried out to identify the factors associated with contraceptive use. Results: The prevalence of contraceptive use …

Disruptive Technologies And Sustainable Development: Implications For Southeast Asia, Ching-Fu Lin, Han-Wei Liu

Research Collection Yong Pung How School Of Law

Disruptive technologies, including artificial intelligence, distributed ledger technologies, and the internet of things, are driving a transformative reorganisation of economic structures. If correctly harnessed, these emerging technologies have the potential to assist economies in creating new efficiencies, boosting productivity, and enhancing international trade. This paper explores the scope for these technologies to contribute to sustainable development, highlighting how they could be deployed and implications for Cambodia, Lao PDR, Myanmar, and Vietnam.

On The Verge Of Diagnosis: Detection, Reporting, And Investigation Of De Novo Variants In Novel Genes Identified By Clinical Sequencing., Isabelle Thiffault, Maxime Cadieux-Dion, Emily G. Farrow, Raymond Caylor, Neil A. Miller, Sarah E. Soden, Carol J. Saunders

Manuscripts, Articles, Book Chapters and Other Papers

The variable evidence supporting gene-disease associations contributes to the difficulty of accurate variant reporting in a clinical setting. An evidence-based scoring system for evaluating the clinical validity of gene-disease associations, proposed by ClinGen, considers experimental as well as genetic evidence. De novo variants are heavily weighted, given the overall rarity in the genome and their contribution to human disease, however they are reported as "genes of unknown significance" in our center when there is insufficient evidence for the gene-disease assertion. We report a collection of 21 de novo variants in genes of unknown clinical significance ascertained via clinical testing, of …

Proteomics Of Human Liver Membrane Transporters: A Focus On Fetuses And Newborn Infants., Bianca D. Van Groen, Evita Van De Steeg, Miriam G. Mooij, Marola M H Van Lipzig, Barbara A E De Koning, Robert M. Verdijk, Heleen M. Wortelboer, R Gaedigk, Chengpeng Bi, J Steven Leeder, Ron H N Van Schaik, Joost Van Rosmalen, Dick Tibboel, Wouter H. Vaes, Saskia N. De Wildt

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples.

METHODS: Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3, NTCP, OCT1, OATP1B1, OATP1B3, OATP2B1 and ATP1A1 were quantified with LC-MS/MS in isolated crude membrane fractions of snap-frozen post-mortem fetal and pediatric, and surgical adult liver samples. mRNA expression was quantified using RNA sequencing, and genetic variants with TaqMan assays. We explored relationships between protein expression and age …

Early Detection Of Disease Using Electronic Health Records And Fisher's Wishart Discriminant Analysis, Sijia Yang, Jian Bian, Zeyi Sun, Licheng Wang, Haojin Zhu, Haoyi Xiong, Yu Li

Engineering Management and Systems Engineering Faculty Research & Creative Works

Linear Discriminant Analysis (LDA) is a simple and effective technique for pattern classification, while it is also widely-used for early detection of diseases using Electronic Health Records (EHR) data. However, the performance of LDA for EHR data classification is frequently affected by two main factors: ill-posed estimation of LDA parameters (e.g., covariance matrix), and "linear inseparability" of the EHR data for classification. To handle these two issues, in this paper, we propose a novel classifier FWDA -- Fisher's Wishart Discriminant Analysis, which is developed as a faster and robust nonlinear classifier. Specifically, FWDA first surrogates the distribution of "potential" inverse …