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2018

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Articles 59341 - 59370 of 62017

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The Protective Effects Of Chrysin And Flunixin Meglumine Against Excess Copper In Male Rats, Pinar Tatli Seven, Burcu Gül Baykalir, İsmai̇l Seven, Tuba Parlak Ak, Neşe Başak Türkmen, Hakan Güllüoğlu Jan 2018

The Protective Effects Of Chrysin And Flunixin Meglumine Against Excess Copper In Male Rats, Pinar Tatli Seven, Burcu Gül Baykalir, İsmai̇l Seven, Tuba Parlak Ak, Neşe Başak Türkmen, Hakan Güllüoğlu

Turkish Journal of Veterinary & Animal Sciences

Thirty-six Sprague Dawley male rats were housed in individual cages and randomly divided into six groups: control, copper sulfate (Cu; 500 ppm body weight (BW)/day), flunixin meglumine (FM; 2.2 ppm BW/day), chrysin (chrysin; 50 ppm BW/day), copper sulfate + FM (Cu + FM; 500 ppm BW/day of copper sulfate and 2.2 ppm BW/day of FM), and copper sulfate + chrysin (Cu + Chrysin; 500 ppm BW/day of copper sulfate and 50 ppm BW/day of chrysin). Feed intake (FI) in the Cu + Chrysin group significantly increased in comparison with that of the Cu group (P < 0.01). Cu excess significantly increased malondialdehyde, indicating oxidative stress. Chrysin and FM administration significantly decreased malondialdehyde levels and increased the superoxide dismutase and catalase activities in the liver and kidney tissues (P < 0.001). Serum TNF-α levels were significantly lower in the Cu + FM and Cu + Chrysin groups in comparison to the Cu group (P < 0.001). It was seen that FM and chrysin treatments alleviated degeneration, necrosis, and apoptosis in the liver and kidney tissues of the Cu-treated rats. Chrysin appeared to ameliorate the adverse effects on FI and liver and kidney tissues by scavenging where the free radicals are located and increasing the activity of antioxidants.

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Complications Of Ultrasound-Guided Cystocentesis In Companion Animals: 21 Cases (2005-2016), Sabrina Manfredi, Cibele Carvalho, Paolo Fonti, Giacomo Gnudi, Francesca Miduri, Martina Fabbi, Eleonora Daga, Manuela Ravera, Simona Morabito, Edoardo Auriemma, Ilaria Parroccini, Mattia Bonazzi, Antonella Volta Jan 2018

Complications Of Ultrasound-Guided Cystocentesis In Companion Animals: 21 Cases (2005-2016), Sabrina Manfredi, Cibele Carvalho, Paolo Fonti, Giacomo Gnudi, Francesca Miduri, Martina Fabbi, Eleonora Daga, Manuela Ravera, Simona Morabito, Edoardo Auriemma, Ilaria Parroccini, Mattia Bonazzi, Antonella Volta

Turkish Journal of Veterinary & Animal Sciences

Complications of cystocentesis in dogs and cats are seldom reported. The aim of this study was to describe clinical and ultrasonographic features of complications after diagnostic cystocentesis. Medical records of animals that underwent ultrasound-guided diagnostic cystocentesis (UGDC) were retrospectively reviewed to describe adverse events. The inclusion criteria were: ultrasound report describing the complication, signalment, clinical history, urine culture, and surgical exploration or necroscopic findings if present. Images of ultrasonographic examination were reviewed. Complications were classified as minor and major. Minor complications were defined as self-limited events; major complications were those that led to prolonged hospitalization and required intensive therapy or …

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Molecular Determination Of Methicillin Resistance Meca And Virulence Coa Genes In Staphylococcus Aureus From Pyogenic Clinical Cases Of Companion Animals In India, Ritika Yadav, Amit Kumar, Vinod Singh, Jayshree Singh, Sharad Kumar Yadav Jan 2018

Molecular Determination Of Methicillin Resistance Meca And Virulence Coa Genes In Staphylococcus Aureus From Pyogenic Clinical Cases Of Companion Animals In India, Ritika Yadav, Amit Kumar, Vinod Singh, Jayshree Singh, Sharad Kumar Yadav

Turkish Journal of Veterinary & Animal Sciences

Out of 100 pyogenic clinical cases of companion animals, 40 samples revealed Staphylococcus aureus confirmed by genomic amplification of 280-bp amplicons of the nuc gene. The presence of resistance and virulence determinants was confirmed for the genomic and plasmid mec, van, and coa genes. Out of 40 isolates of S. aureus, 23 isolates revealed amplification of 533-bp mecA genes on genomic DNA. These included 4, 14, and 5 isolates of cattle, buffalo, and dogs, respectively. On amplification for the coa gene, 19 isolates revealed amplicons of variable size and number on genomic DNA. The numbers of coa-positive isolates were 4, …

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Assessment Of Tumor-Induced Pain And C-Reactive Protein Levels In Dogs With Caninetransmissible Venereal Tumors, Waqas Ahmad, Muti-Ur- Rehman, Aftab Ahmad Anjum, Gulbeena Saleem, Ubaid Ur Rehman Zia, Muhammad Azeem, Fahad Akram Jan 2018

Assessment Of Tumor-Induced Pain And C-Reactive Protein Levels In Dogs With Caninetransmissible Venereal Tumors, Waqas Ahmad, Muti-Ur- Rehman, Aftab Ahmad Anjum, Gulbeena Saleem, Ubaid Ur Rehman Zia, Muhammad Azeem, Fahad Akram

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the impact of tumor volume on generalized behavior, pain perception, and serum C-reactive protein (CRP) in dogs with canine transmissible venereal tumors (CTVTs). Pain scoring was performed using the Glasgow Composite Measure Pain Scale Short-Form. Cytomorphology of the tumors was studied through fine-needle aspiration and histopathology. Molecular identification of CTVTs was carried out using PCR assays based on LINE-1/c-myc. Hematological profiles including complete blood count and CRP were analyzed using an automatic hematology analyzer and immunoturbidimetric assays, respectively. Chi-square and regression analysis statistics were used for data analysis. Results of the study …

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Cover And Contents Jan 2018

Cover And Contents

Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

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Uterine Prolapse In A Pregnant Cat, Zeynep Günay Uçmak, Meli̇h Uçmak, Ali̇ Can Çeti̇n, Çağatay Tek Jan 2018

Uterine Prolapse In A Pregnant Cat, Zeynep Günay Uçmak, Meli̇h Uçmak, Ali̇ Can Çeti̇n, Çağatay Tek

Turkish Journal of Veterinary & Animal Sciences

A 3-year-old, 2.5-kg British shorthair cat with dystocia and protrusion of a mass through the vulva was presented to the Obstetrics and Gynaecology Clinic, Faculty of Veterinary Medicine, İstanbul University. Upon clinical examination, a complete uterine prolapse was diagnosed. Because of a blood blister and oedema in the uterine horns, ovariohysterectomy treatment was decided. During laparotomy, one foetus was detected in the cranial portion of the left uterine horn. After manual reduction and intraabdominal withdrawal of the prolapsed uterus, a caesarean section was performed to deliver the foetus. The last litter and the queen were discharged from the clinic in …

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Exercise Dependence And Shin Pain In A Division I Cross-Country Runner: A Case Study, Allyssa K. Memmini Jan 2018

Exercise Dependence And Shin Pain In A Division I Cross-Country Runner: A Case Study, Allyssa K. Memmini

Clinical Practice in Athletic Training

The following case investigates insidious onset of shin pain in a Division I female cross-country runner. Though her initial evaluation revealed early onset medial tibial stress syndrome, the sequence of events that occurred immediately afterwards is what makes this case unique. As the student-athlete underwent lower extremity rehabilitation to increase her mileage, she reported that her pain had plateaued. The initial x-ray revealed a periosteal reaction of the posterior left tibia. After adhering to the treatment plan for four weeks, the student-athlete continued to report significant bouts of pain as demonstrated by the Visual Analog Scale. A follow-up x-ray revealed …

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Guidelines For Useful Integration Of Patient-Rated Outcome Measures Into Clinical Practice, Skye Livermore-Brasher, Russell Baker, Alan Nasypany, Scott Cheatham Jan 2018

Guidelines For Useful Integration Of Patient-Rated Outcome Measures Into Clinical Practice, Skye Livermore-Brasher, Russell Baker, Alan Nasypany, Scott Cheatham

Clinical Practice in Athletic Training

No abstract provided.

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Acute Management Of An Abductor Digiti Minimi Strain In A Collegiate Baseball Player: A Patient-Centered Case Study, S. Andrew Cage, Diana M. Gallegos, Brandon J. Warner Jan 2018

Acute Management Of An Abductor Digiti Minimi Strain In A Collegiate Baseball Player: A Patient-Centered Case Study, S. Andrew Cage, Diana M. Gallegos, Brandon J. Warner

Clinical Practice in Athletic Training

The purpose of this disablement model case study was to describe the case of a collegiate baseball player suffering from an isolated abductor digiti minimi strain. Despite an initial decrease in function, the treating sports medicine staff was able to provide the necessary care to allow the patient to participate in the final games of his career. While the anatomy and function of abductor digiti minimi are well described in the literature, there is no documentation of isolated abductor digiti minimi injuries. In this case, the patient injured the medial aspect of his hand when hitting a baseball. The patient …

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Morphometric And Genetic Variability Among Mediterranean Cereal Cyst Nematode (Heterodera Latipons) Populations In Turkey, Mustafa İmren, Şenol Yildiz, Hali̇l Toktay, Nagi̇han Duman, Abdelfattah A. Dababat Jan 2018

Morphometric And Genetic Variability Among Mediterranean Cereal Cyst Nematode (Heterodera Latipons) Populations In Turkey, Mustafa İmren, Şenol Yildiz, Hali̇l Toktay, Nagi̇han Duman, Abdelfattah A. Dababat

Turkish Journal of Zoology

The Mediterranean cereal cyst nematode, Heterodera latipons, is an important plant parasitic nematode that negatively impacts cereal production worldwide, particularly in the Mediterranean Basin. Successful control of cereal cyst nematodes requires knowledge of the nematode species/pathotypes and their biology. However, little information is currently available concerning the phenotypic and genotypic variability of H. latipons populations in Turkey. This study analyzed the morphological/morphometric and genetic characteristics of Turkish H. latipons populations to define intraspecific distinctions between them. Morphological and morphometric studies focused on the pattern of the perineal region of cysts and second stage juveniles (J2), while the molecular analyses used …

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Standard Weight Equations Of Two Sub-/Tropic Nonnative Freshwater Fish, Clarias Gariepinus And Oreochromis Niloticus, In The Sakarya River Basin (Nw Turkey), Özgür Emi̇roğlu, Sercan Başkurt, Sadi̇ Aksu, Daniela Giannetto, Ali̇ Serhan Tarkan Jan 2018

Standard Weight Equations Of Two Sub-/Tropic Nonnative Freshwater Fish, Clarias Gariepinus And Oreochromis Niloticus, In The Sakarya River Basin (Nw Turkey), Özgür Emi̇roğlu, Sercan Başkurt, Sadi̇ Aksu, Daniela Giannetto, Ali̇ Serhan Tarkan

Turkish Journal of Zoology

Clarias gariepinus and Oreochromis niloticus are two hot-water fish species of African origin that have been recently reported to occur unnaturally in hot-water resources and springs in the Sakarya River Basin (northwestern Turkey). Within effective planning strategies to maintain native biodiversity, monitoring fishes' well-being can be useful to evaluate the status of nonnative fish populations and their degree of adaptation to new environments. Relative weight (W$_{r}$) is a condition index widely used to estimate the well-being of fish by comparing the actual weight of a specimen with a standard weight (W$_{s}$) that is the ideal weight of that fish at …

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Polycythemia Vera: Diagnosis, Clinical Course, And Current Management, Yahya Büyükaşik, Ridvan Ali̇, Muhli̇s Cem Ar, Mehmet Turgut, Aki̇f Seli̇m Yavuz, Güray Saydam Jan 2018

Polycythemia Vera: Diagnosis, Clinical Course, And Current Management, Yahya Büyükaşik, Ridvan Ali̇, Muhli̇s Cem Ar, Mehmet Turgut, Aki̇f Seli̇m Yavuz, Güray Saydam

Turkish Journal of Medical Sciences

Very important developments related to polycythemia vera (PV) have occurred during the last two decades. The discovery of Janus kinase (JAK) 2 mutations has changed both the diagnosis and clinical management of PV. Currently JAK2 molecular testing is essential in the diagnostic work-up and JAK2 mutation positivity is a major diagnostic criterion. The discovery of JAK2 mutations suggested that abnormal JAK-STAT signaling was a pivotal feature in the pathogenesis of Philadelphia-negative myeloproliferative neoplasms. This idea led to the development of JAK inhibitors. Currently ruxolitinib, a JAK1/JAK2 inhibitor, is also approved for PV patients with hydroxyurea resistance or intolerance. International collaborations …

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Antibiotic Treatment Outcomes In Community-Acquired Pneumonia, Aykut Çi̇lli̇, Abdullah Sayiner, Burcu Çelenk, Ayşin Şakar Coşkun, Oğuz Kilinç, Armağan Hazar, Anil Aktaş Samur, Sezai̇ Taşbakan, Grant W. Waterer, Yavuz Havlucu, Öznur Kiliç, Fatma Tokgöz, Uğur Bi̇lge Jan 2018

Antibiotic Treatment Outcomes In Community-Acquired Pneumonia, Aykut Çi̇lli̇, Abdullah Sayiner, Burcu Çelenk, Ayşin Şakar Coşkun, Oğuz Kilinç, Armağan Hazar, Anil Aktaş Samur, Sezai̇ Taşbakan, Grant W. Waterer, Yavuz Havlucu, Öznur Kiliç, Fatma Tokgöz, Uğur Bi̇lge

Turkish Journal of Medical Sciences

Background/aim: The optimal empiric antibiotic regimen for patients with community-acquired pneumonia (CAP) remains unclear. This study aimed to evaluate the clinical cure rate, mortality, and length of stay among patients hospitalized with communityacquired pneumonia in nonintensive care unit (ICU) wards and treated with a ß-lactam, ß-lactam and macrolide combination, or a fluoroquinolone. Materials and methods: This prospective cohort study was performed using standardized web-based database sheets from January 2009 to September 2013 in nine tertiary care hospitals in Turkey. Results: Six hundred and twenty-one consecutive patients were enrolled. A pathogen was identified in 78 (12.6%) patients. The most frequently isolated …

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Cytoplasmic Abnormalities Of Mature Oocytes Have A Significant Effect On Fertilization Inbologna Poor Responders, Halenur Bozdağ, Esra Akdeni̇z, Belgi̇n Devranoğlu, Murat Haksever, Bülent Emre Bi̇lgi̇ç, Hüseyi̇n Tayfun Kutlu Jan 2018

Cytoplasmic Abnormalities Of Mature Oocytes Have A Significant Effect On Fertilization Inbologna Poor Responders, Halenur Bozdağ, Esra Akdeni̇z, Belgi̇n Devranoğlu, Murat Haksever, Bülent Emre Bi̇lgi̇ç, Hüseyi̇n Tayfun Kutlu

Turkish Journal of Medical Sciences

Background/aim: We aimed to investigate whether oocyte morphologic abnormalities affected cycle outcome in poor responder infertile women who fulfilled the Bologna criteria. Materials and methods: Data were obtained from infertile couples who underwent ICSI and embryo transfer at the Zeynep Kamil Maternity and Children's Health Training and Research Hospital Assisted Reproduction Unit in İstanbul, Turkey. They were allocated to two groups: Group A, poor responders, and Group B, normal responders. All morphological abnormalities of oocytes retrieved were reviewed and grouped as cytoplasmic abnormalities or extracytoplasmic abnormalities. All morphological features were compared between the poor and normal responder groups. ICSI cycle …

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Effect Of Intraoperative Infusion Of Sufentanil Versus Remifentanil On Postoperativeshivering In Korea: A Prospective, Double-Blinded, Randomized Control Study, Ki Tae Jung, Keum Young So, In Gook Jee, Sang Hun Kim Jan 2018

Effect Of Intraoperative Infusion Of Sufentanil Versus Remifentanil On Postoperativeshivering In Korea: A Prospective, Double-Blinded, Randomized Control Study, Ki Tae Jung, Keum Young So, In Gook Jee, Sang Hun Kim

Turkish Journal of Medical Sciences

Background/aim: The number of published papers that compare the incidence of sufentanil- and remifentanil-related postoperative shivering is insufficient. We investigated the incidence of postoperative shivering after total intravenous anesthesia with either sufentanil or remifentanil in patients who underwent elective surgery. Materials and methods: Eighty-three patients, with a physical status classified as American Society of Anesthesiologists I or II, were randomly allocated to either the remifentanil-propofol (RP group, n = 40) or sufentanil-propofol (SP group, n = 43) group. The primary endpoint was the incidence of postoperative shivering 1 h after entering the recovery room. The secondary endpoints were intraoperative core …

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Detection Of Ccnd1, C-Myc, And Fgfr1 Amplification Using Modified Sybr Green Qpcr And Fish In Breast Cancer, Asaad Azarnezhad, Mina Tabrizi, Firozeh Javan, Parvin Mehdipour Jan 2018

Detection Of Ccnd1, C-Myc, And Fgfr1 Amplification Using Modified Sybr Green Qpcr And Fish In Breast Cancer, Asaad Azarnezhad, Mina Tabrizi, Firozeh Javan, Parvin Mehdipour

Turkish Journal of Medical Sciences

Background/aim: The aims of this study were to detect CCND1, C-MYC, and FGFR1 amplification using qPCR, confirmation with FISH, and to further assess their clinicopathological relevance. Materials and methods: Thirty-five breast tumor samples were analyzed for amplification of the selected genes using modified SYBR Green qPCR. The accuracy of the qPCR was assessed by FISH as a gold-standard method. Results: CCND1, C-MYC, and FGFR1 amplifications were observed in 34.28%, 28.57%, and 17.14% of the 35 samples, respectively. qPCR results were significantly confirmed by FISH and qPCR and FISH showed excellent correlation (P = 0.000). CCND1 amplification with tumor stage (P …

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Detection Of The Differences In The Apparent Diffusion Coefficient Values In Differenthistopathological Types Of Malignant Breast Lesions And Comparison Of Cellular Region/Stroma Ratio And Histopathological Results, Nevi̇n Köremezli̇ Keski̇n, Pinar Balci, Işil Başara Akin, Esra Yavuz Gürkan, Ali̇ İbrahi̇m Sevi̇nç, Meri̇h Güray Durak, Ayça Erşen Danyeli̇ Jan 2018

Detection Of The Differences In The Apparent Diffusion Coefficient Values In Differenthistopathological Types Of Malignant Breast Lesions And Comparison Of Cellular Region/Stroma Ratio And Histopathological Results, Nevi̇n Köremezli̇ Keski̇n, Pinar Balci, Işil Başara Akin, Esra Yavuz Gürkan, Ali̇ İbrahi̇m Sevi̇nç, Meri̇h Güray Durak, Ayça Erşen Danyeli̇

Turkish Journal of Medical Sciences

Background/aim: This study aimed to compare the apparent diffusion coefficient (ADC) values of malignant breast lesions with different histopathological types on diffusion-weighted imaging (DWI) and the cellular region/stroma (CR/S) ratio and histopathological results. Materials and methods: Breast diffusion-weighted magnetic resonance findings of 59 patients were retrospectively analyzed for malignant breast lesions. The CR/S ratio was calculated using breast wide-excisional biopsy or mastectomy specimens. Results: Receiver operating characteristic analysis was performed for malignant lesions and subtypes. An ADC threshold of 1.260 × 10-3 mm2/s was set to detect invasive ductal carcinoma with 80.8% sensitivity and 81.4% specificity. An ADC threshold of …

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Rising Stars Of Dpld Survival: Fvc And Exercise Desaturation (A Single-Center Study), Ayperi̇ Öztürk, Oya Kayacan Jan 2018

Rising Stars Of Dpld Survival: Fvc And Exercise Desaturation (A Single-Center Study), Ayperi̇ Öztürk, Oya Kayacan

Turkish Journal of Medical Sciences

Background/aim: Diffuse parenchymal lung diseases (DPLDs) comprise a broad, heterogeneous group of diseases with common functional characteristics and a common final pathway, usually leading to irreversible fibrosis. We investigated the effects of the physiological and functional parameters and of pulmonary hypertension (PH) on survival in DPLDs. Materials and methods: The study included 158 patients with DPLDs. Patient data were examined retrospectively, and survival status was obtained through phone calls. Results: Patients were divided into five groups according to their diagnosis: idiopathic pulmonary fibrosis (IPF), non-IPF idiopathic interstitial pneumonias, connective tissue diseases, sarcoidosis, and other DPLDs. Median survival was 42.9 months. …

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The Impact Of Donor And Recipient Kir Genes And Kir Ligands On The Occurrence Of Acutegraft-Versus-Host Disease And Graft Survival After Hla-Identical Sibling Hematopoieticstem Cell Transplantation, Seyed Ahmad Hoseinian, Davood Jafari, Mehdi Mahmoodi, Kamran Alimoghaddam, Mohammadreza Ostadali, Azita Talebzadeh Bonakdar, Arron Munggela Foma, Mir Saeed Yekaninejad, Ali Akbar Amirzargar Jan 2018

The Impact Of Donor And Recipient Kir Genes And Kir Ligands On The Occurrence Of Acutegraft-Versus-Host Disease And Graft Survival After Hla-Identical Sibling Hematopoieticstem Cell Transplantation, Seyed Ahmad Hoseinian, Davood Jafari, Mehdi Mahmoodi, Kamran Alimoghaddam, Mohammadreza Ostadali, Azita Talebzadeh Bonakdar, Arron Munggela Foma, Mir Saeed Yekaninejad, Ali Akbar Amirzargar

Turkish Journal of Medical Sciences

Background/aim: After allogeneic hematopoietic stem cell transplantation (allo-HSCT), donor natural killer (NK) cells trigger alloreactions against potential recipient cells by their killer immunoglobulin-like receptors (KIRs). This study investigated whether KIR/HLA genotypes and KIR haplotypes of donors and recipients exhibit a critical function in the prevalence of acute graft-versus-host disease (aGVHD) and persistence of the graft after HLA-identical sibling allo-HSCT for patients with hematological malignancies. Materials and methods: We studied KIR and HLA genotypes in 115 related donors and recipients (56 patients with AML and 59 patients with ALL) who had received allo-HSCT from HLA-matched sibling donors. We evaluated 17 KIR …

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Reliability And Validity Of The Turkish Version Of Pain Assessment Checklist For Seniorswith Limited Ability To Communicate (Pacslac-T), Öznur Büyükturan, Buket Büyükturan, Aysu Yeti̇ş, Mehmet İlki̇n Naharci, Nuray Kirdi Jan 2018

Reliability And Validity Of The Turkish Version Of Pain Assessment Checklist For Seniorswith Limited Ability To Communicate (Pacslac-T), Öznur Büyükturan, Buket Büyükturan, Aysu Yeti̇ş, Mehmet İlki̇n Naharci, Nuray Kirdi

Turkish Journal of Medical Sciences

Background/aim: This study aimed to assess validity and reliability of the Turkish version of Pain Assessment Checklist for Seniors with Limited Ability to Communicate (PACSLAC-T). Materials and methods: The individuals who met inclusion criteria of the study were in patients of a hospital and a long-term care facility. Mini Mental Status Exam (MMSE), Cornell Dementia Depression Scale (CDDS), Global Deterioration Scale (GDS), visual analogue scale (VAS), and PACSLAC-T were administered to all subjects. The scales were repeated with an interval of two weeks for test-retest reliability. Results: A total of 112 patients with dementia were included in the study. The …

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The In Vitro Effect Of Antimicrobial Photodynamic Therapy Oncandida And Staphylococcus Biofilms, Özlem Güzel Tunçcan, Ayşe Kalkanci, Eli̇f Ayça Ünal, Olkar Abdulmajed, Merve Erdoğan, Murat Di̇zbay, Kayhan Çağlar Jan 2018

The In Vitro Effect Of Antimicrobial Photodynamic Therapy Oncandida And Staphylococcus Biofilms, Özlem Güzel Tunçcan, Ayşe Kalkanci, Eli̇f Ayça Ünal, Olkar Abdulmajed, Merve Erdoğan, Murat Di̇zbay, Kayhan Çağlar

Turkish Journal of Medical Sciences

Background/aim: This study was designed to evaluate the effect of antimicrobial photodynamic treatment (APDT) in a biofilm model using combinations of various dyes (rose bengal, riboflavin, and methylene blue) as photosensitizers and light sources (LED and UVA) against staphylococcal and candidal biofilms. Materials and methods: Sterile microtiter plates were used for the development and quantification of the biofilms. APDT was carried out using combinations of the light sources and dyes. The percentage of the growth inhibition was then calculated using a spectrophotometer. The broth media in the wells were aspirated, wells were stained with crystal violet, and optical density values …

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Octreotide Ameliorates Dermal Fibrosis In Bleomycin-Induced Scleroderma, Si̇bel Oyucu Orhan, Ahmet Tektemur, Nevzat Gözel, İbrahi̇m Hani̇fi̇ Özercan, Servet Yolbaş, Ahmet Yildirim, Ebru Önalan, Süleyman Serdar Koca Jan 2018

Octreotide Ameliorates Dermal Fibrosis In Bleomycin-Induced Scleroderma, Si̇bel Oyucu Orhan, Ahmet Tektemur, Nevzat Gözel, İbrahi̇m Hani̇fi̇ Özercan, Servet Yolbaş, Ahmet Yildirim, Ebru Önalan, Süleyman Serdar Koca

Turkish Journal of Medical Sciences

Background/aim: Insulin-like growth factor (IGF)-I is a differentiation and growth factor. Antifibrotic action of octreotide has been reported in pulmonary fibrosis. The present study aimed to research the prophylactic and therapeutic potential of octreotide on a bleomycin (BLM)-induced experimental scleroderma model. Materials and methods: Sixty Balb/c female mice were divided into 6 groups. Daily subcutaneous BLM (100 μg) was injected for 3 weeks in groups II and III and for 6 weeks in groups V and VI. Octreotide (100 μg/kg per day) was injected subcutaneously for the first 3 weeks in group III (prophylactic) and the second 3 weeks in …

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Hand Functions In Systemic Lupus Erythematosus: A Comparative Study With Rheumatoidarthritis Patients And Healthy Subjects, Songül Bağlan Yentür, Zeynep Tuna, Oğuzhan Mete, Ahmet Gökkurt, Nurten Gi̇zem Tore, Hami̇t Küçük, Berna Göker, Deran Oskay Jan 2018

Hand Functions In Systemic Lupus Erythematosus: A Comparative Study With Rheumatoidarthritis Patients And Healthy Subjects, Songül Bağlan Yentür, Zeynep Tuna, Oğuzhan Mete, Ahmet Gökkurt, Nurten Gi̇zem Tore, Hami̇t Küçük, Berna Göker, Deran Oskay

Turkish Journal of Medical Sciences

Background/aim: Systemic lupus erythematosus (SLE) frequently affects the small joints of the hand and may result in difficulty in activities of daily living. There are very few studies evaluating the problems encountered in the hands in patients with SLE. The aim of this study is to evaluate hand functions in patients with SLE and compare them with rheumatoid arthritis (RA) patients and healthy subjects. Materials and methods: A total 46 female patients meeting the SLE classification criteria were recruited. Similarly, 51 female RA patients and 46 healthy female subjects served as the control groups. To assess the upper extremity disability …

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Methodology Of A New Inflammatory Arthritis Registry: Treasure, Umut Kalyoncu, Etem Koray Taşcilar, Ali̇ İhsan Ertenli̇, Hüseyi̇n Edi̇z Dalkiliç, Cemal Bes, Orhan Küçükşahi̇n, Ti̇muçi̇n Kaşi̇foğlu, Ni̇lüfer Alpay Kanitez, Hakan Emmungi̇l, Gezmi̇ş Ki̇myon, Nazi̇fe Şule Yaşar Bi̇lge, Servet Akar, Mehmet Pami̇r Atagündüz, Süleyman Serdar Koca, Aşkin Ateş Jan 2018

Methodology Of A New Inflammatory Arthritis Registry: Treasure, Umut Kalyoncu, Etem Koray Taşcilar, Ali̇ İhsan Ertenli̇, Hüseyi̇n Edi̇z Dalkiliç, Cemal Bes, Orhan Küçükşahi̇n, Ti̇muçi̇n Kaşi̇foğlu, Ni̇lüfer Alpay Kanitez, Hakan Emmungi̇l, Gezmi̇ş Ki̇myon, Nazi̇fe Şule Yaşar Bi̇lge, Servet Akar, Mehmet Pami̇r Atagündüz, Süleyman Serdar Koca, Aşkin Ateş

Turkish Journal of Medical Sciences

Background/aim: The TReasure registry, created in 2017, is an observational multicenter cohort that includes inflammatory arthritis patients. This article reviews the methodology and objectives of the TReasure registry established to collect data from rheumatoid arthritis (RA) and spondyloarthritis (SpA) patients. Methodology: Fifteen rheumatology centers in Turkey will contribute data to the TReasure database. The actual proprietor of the database is the Hacettepe Rheumatology Association (HRD) and Hacettepe Financial Enterprises. Pharmaceutical companies that operate in Turkey (in alphabetical or er), Abbvie, Amgen, BMS, Celltrion Healthcare, Novartis, Pfizer, Roche, and UCB, support the TReasure registry. TReasure is a web-based database to which …

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Effects Of Volume-Controlled Equal Ratio Ventilation With Recruitment Maneuver Andpositive End-Expiratory Pressure In Laparoscopic Sleeve Gastrectomy: A Prospective,Randomized, Controlled Trial, Bahatti̇n Tuncali, Varlik Erol, Pinar Zeyneloğlu Jan 2018

Effects Of Volume-Controlled Equal Ratio Ventilation With Recruitment Maneuver Andpositive End-Expiratory Pressure In Laparoscopic Sleeve Gastrectomy: A Prospective,Randomized, Controlled Trial, Bahatti̇n Tuncali, Varlik Erol, Pinar Zeyneloğlu

Turkish Journal of Medical Sciences

Background/aim: We compared the effects of volume-controlled equal ratio ventilation (VC-ERV) and volume-controlled conventional ratio ventilation (VC-CRV) on oxygenation, ventilation, respiratory mechanics, and hemodynamic status during mechanical ventilation with recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) in patients undergoing laparoscopic sleeve gastrectomy. Materials and methods: A total of 111 patients scheduled for laparoscopic sleeve gastrectomy were randomized to ventilation with inspiratory to expiratory ratio of 1:1 (Group VC-ERV) or 1:2 (Group VC-CRV) following tracheal intubation. RM (40 cmH2O, 15 s) and PEEP (10 cmH2O) were administered to all patients. Arterial blood gas samples were taken and peak airway pressure …

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Cover And Contents Jan 2018

Cover And Contents

Turkish Journal of Medical Sciences

No abstract provided.

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Ginger (Zingiber Officinale) Prevents Severe Damage To The Lungs Due To Hyperoxia Andinflammation, Ati̇lla Çi̇fci̇, Cüneyt Tayman, Hali̇l İbrahi̇m Yakut, Hali̇t Hali̇l, Esra Çakir, Ufuk Çakir, Sali̇h Aydemi̇r Jan 2018

Ginger (Zingiber Officinale) Prevents Severe Damage To The Lungs Due To Hyperoxia Andinflammation, Ati̇lla Çi̇fci̇, Cüneyt Tayman, Hali̇l İbrahi̇m Yakut, Hali̇t Hali̇l, Esra Çakir, Ufuk Çakir, Sali̇h Aydemi̇r

Turkish Journal of Medical Sciences

Background/aim: Hyperoxia- and inflammation-induced lung injury is an important cause of the development of bronchopulmonary dysplasia (BPD) in premature infants. We aimed to ascertain the beneficial effects of ginger (Zingiber officinale) on rat pups exposed to hyperoxia and inflammation. Materials and methods: Thirty-six newborn Wistar rats were randomly divided into 3 groups as the hyperoxia (95% O2) + lipopolysaccharide (LPS) group, the hyperoxia + LPS + ginger-treated group, and the control/no treatment group (21% O2). Pups in the hyperoxia + LPS + ginger group were administered oral ginger at a dose of 1000 mg/kg daily during the study period. Histopathologic, …

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Multitarget Therapy Versus Intravenous Cyclophosphamide In The Induction Treatment Of Lupus Nephritis: A Metaanalysis Of Randomized Controlled Trials, Jin Deng, Lei Luo, Lin Zhu, Huan Xie, Hong-Ping Xie Jan 2018

Multitarget Therapy Versus Intravenous Cyclophosphamide In The Induction Treatment Of Lupus Nephritis: A Metaanalysis Of Randomized Controlled Trials, Jin Deng, Lei Luo, Lin Zhu, Huan Xie, Hong-Ping Xie

Turkish Journal of Medical Sciences

Background/aim: Multitarget therapy for lupus nephritis (LN) remains in its exploratory phrase and the recent evidence is insufficient. This study aimed to evaluate the efficacy and safety of mycophenolate mofetil (MMF), tacrolimus (TAC), and steroids (multitarget therapy) versus intravenous cyclophosphamide (IVC) and steroids in induction treatment of LN. Materials and methods: We searched for randomized controlled trials of MMF plus TAC versus IVC in LN using PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, the China Biology Medicine Database, and the China National Knowledge Infrastructure Database. We assessed the retrieved citations and selected studies according to predefined inclusion and …

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Ultrasonographic And Clinical Evaluation Of Additional Contribution Of Kinesiotaping Totendon And Nerve Gliding Exercises In The Treatment Of Carpal Tunnel Syndrome, Pinar Yildirim, Banu Di̇lek, Ebru Şahi̇n, Selmi̇n Gülbahar, Ramazan Kizil Jan 2018

Ultrasonographic And Clinical Evaluation Of Additional Contribution Of Kinesiotaping Totendon And Nerve Gliding Exercises In The Treatment Of Carpal Tunnel Syndrome, Pinar Yildirim, Banu Di̇lek, Ebru Şahi̇n, Selmi̇n Gülbahar, Ramazan Kizil

Turkish Journal of Medical Sciences

Background and aim: This study aims to ultrasonographically and clinically evaluate the additive contribution of kinesiotaping to tendon and nerve gliding exercises in the treatment of mild or moderate carpal tunnel syndrome (CTS). Materials and methods: Thirty-eight wrists of patients (n = 21) with CTS were randomized into two groups as the intervention group (n = 19) and the control group (n = 19). Tendon and nerve gliding exercises were given to both groups. In the intervention group, additional kinesiotaping was performed three times with 5-day intervals. Functional assessments were performed with the Boston Carpal Tunnel Syndrome Questionnaire and the …

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Typing Of Chronic Obstructive Pulmonary Disease Using High-Resolution Computedtomography And The Association With Smoking, Airway Inflammation, And Commoncomorbidities, Zheng Liu, Yan Wang, Ying Liu, Mengmiao Pei, Jing Li, Fang Shi, Peixiu Li Jan 2018

Typing Of Chronic Obstructive Pulmonary Disease Using High-Resolution Computedtomography And The Association With Smoking, Airway Inflammation, And Commoncomorbidities, Zheng Liu, Yan Wang, Ying Liu, Mengmiao Pei, Jing Li, Fang Shi, Peixiu Li

Turkish Journal of Medical Sciences

Background/aim: This study performed typing of chronic obstructive pulmonary disease (COPD) using high-resolution computed tomography (HRCT) to determine the association with smoking, matrix metalloproteinases, and common comorbidities. Materials and methods: The study enrolled 94 hospitalized patients. Participants were divided into a group of 69 current and former smokers (group A) and a group of 25 that had never smoked (group B). Patients were also divided into 3 categories according to the degree of emphysema and bronchial wall thickness using HRCT to determine the association with levels of matrix metalloproteinase 9 (MMP-9) and TIMP-1, as well as associated comorbidities. These three …

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