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2018

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Semiparametric Maximum Likelihood Inference For Nonignorable Nonresponse With Callbacks, Zhong Guan, Denis H. Y. Leung, Jing Qin Dec 2018

Semiparametric Maximum Likelihood Inference For Nonignorable Nonresponse With Callbacks, Zhong Guan, Denis H. Y. Leung, Jing Qin

Research Collection School Of Economics

We model the nonresponse probabilities as logistic functions ofthe outcome variable and other covariates in the survey sampling study withcallback. The identification aspect of this callback model is investigated. Semiparametricmaximum likelihood estimators of the parameters in the responseprobabilities are proposed and studied. As a result, an efficient estimator ofthe mean of the outcome variable is constructed using the estimated responseprobabilities. Moreover, if a regression model for conditional mean of the outcomevariable given some covariate is available, then we can obtain an evenmore efficient estimate of the mean of the outcome variable by fitting the regressionmodel using an adjusted least squares …


Hexaco Personality Predicts Counterproductive Work Behavior And Organizational Citizenship Behavior In Low-Stakes And Job Applicant Contexts, Jeromy Anglim, Filip Lievens, Lisa Everton, Sharon L. Grant, Andrew Marty Dec 2018

Hexaco Personality Predicts Counterproductive Work Behavior And Organizational Citizenship Behavior In Low-Stakes And Job Applicant Contexts, Jeromy Anglim, Filip Lievens, Lisa Everton, Sharon L. Grant, Andrew Marty

Research Collection Lee Kong Chian School Of Business

This study examined the degree to which the predictive validity of personality declines in job applicant settings. Participants completed the 200-item HEXACO Personality Inventory-Revised, either as part of confidential research (347 non-applicants) or an actual job application (260 job applicants). Approximately 18-months later, participants completed a confidential survey measuring organizational citizenship behavior (OCB) and counterproductive work behavior (CWB). There was evidence for a small drop in predictive validity among job applicants, however honesty-humility, extraversion, agreeableness, and conscientiousness predicted lower levels of CWB and higher levels of OCB in both job applicants and non -applicants. The study also informs the use …


Investigating Autophagy Dysfunction Induced By A Parkinson's Disease-Causing Mutation In Vps35, Abir Ashfakur Rahman Dec 2018

Investigating Autophagy Dysfunction Induced By A Parkinson's Disease-Causing Mutation In Vps35, Abir Ashfakur Rahman

Boise State University Theses and Dissertations

Parkinson’s Disease (PD) is an idiopathic disorder with no known cure. With number of cases steadily rising around the world, it is imperative to turn to the underlying cellular and molecular mechanisms of the disease manifestation and neurodegeneration to craft novel modes of therapy. VPS35 is one of the few genes that have identified and definitively linked to familial PD. The particular mutation that has been associated is known to cause dysfunction of a key cellular process known as autophagy. This process is primarily responsible for clearance of unwanted, damaged or misfolded proteins, among other things. Our study reveals an …


Effect Of Subsurface Conditions On Flexible Pavement Behavior: Non-Destructive Testing And Mechanistic Analysis, Md. Fazle Rabbi Dec 2018

Effect Of Subsurface Conditions On Flexible Pavement Behavior: Non-Destructive Testing And Mechanistic Analysis, Md. Fazle Rabbi

Boise State University Theses and Dissertations

The behavior of flexible pavements under traffic and environmental loading can be significantly affected by subsurface conditions. Inadequate support conditions under the surface can lead to excessive pavement deformations, often leading to structural and functional failure. This research effort focused on assessing the effects of base/subbase and subgrade layer conditions on flexible pavement behavior. The results of this study are presented in the form of two journal manuscripts.

The first manuscript focuses on utilizing pavement structural and functional evaluation data in making pavement rehabilitation decisions. Visual distress surveys and Falling Weight Deflectometer (FWD) testing are often carried out by agencies …


Improving Teamwork And Timeliness Of Insulin Administration In The Respiratory Rehabilitation Unit, Jessie Ventura Dec 2018

Improving Teamwork And Timeliness Of Insulin Administration In The Respiratory Rehabilitation Unit, Jessie Ventura

Master's Projects and Capstones

The microsystem assessment conducted by a Clinical Nurse Leader student at an acute care hospital in the Respiratory Rehabilitation Unit (RRU) revealed that two of eight patients were diagnosed with diabetes. The RRU nursing staff was 80% compliant with best practices related to insulin coverage administration within 30 minutes after a point of care blood glucose check. The practice improvement project aims to increase staff awareness and timely administration of insulin coverage by introducing situation monitoring, a core component of Team Strategies and Tools to Enhance Performance and Patient Safety (TeamSTEPPS). After baseline data collection, a 30-minute education intervention was …


Time-Varying Transmission Between Oil And Equities In The Mena Region: New Evidence From Dcc-Midas Analyses, B Awartani, F Javed, A Maghyereh, N Virk Dec 2018

Time-Varying Transmission Between Oil And Equities In The Mena Region: New Evidence From Dcc-Midas Analyses, B Awartani, F Javed, A Maghyereh, N Virk

Plymouth Business School

In this paper we use the DCC-MIDAS (Dynamic Conditional Correlation-Mixed Data Sampling) model to infer the association between oil and equities in five MENA countries between February 2006 and April 2017. The model indicates that higher oil returns tends to reduce the long-term risk of the Saudi market, but to increase it in other markets. The risk transfer from oil to MENA equities is found to be weak. The dynamic conditional correlation between oil and equities is not always positive and it unexpectedly changes sign during the sample period. However, the association always strengthens when there is a large draw …


Ambulance Clinicians’ Perceptions, Assessment And Management Of Frailty: Thematic Analysis Of Focus Groups, J Green, K Kirby, S Hope Dec 2018

Ambulance Clinicians’ Perceptions, Assessment And Management Of Frailty: Thematic Analysis Of Focus Groups, J Green, K Kirby, S Hope

School of Health Professions

No abstract provided.


Look Before You Jump, Kapil R. Tuli Dec 2018

Look Before You Jump, Kapil R. Tuli

Research Collection Lee Kong Chian School Of Business

Coming to grips with the reality of eLearning. In boardrooms all over the world today a scenario is played out again and again: Chief Learning Officers (CLOs) enthusiastically pitch the strategy of eLearning while chief executives remain sceptical over the outcomes. For years, eLearning appeared to be the perfect answer for corporations that need to train their employees. And it certainly has its advantages.


Sources Of Health Financing And Health Outcomes: A Panel Data Analysis, Tomoki Fujii Dec 2018

Sources Of Health Financing And Health Outcomes: A Panel Data Analysis, Tomoki Fujii

Research Collection School Of Economics

We study the differential impacts of public and private sources of health spending on health outcomes using a triple difference approach. We find that private health spending has on average a higher health-promoting effect than public health spending. This result is robust with respect to the choice of outcome measure and covariates in the regression and driven primarily by the countries with ineffective governments. Once we restrict our sample to countries with effective governments, private health spending is no better than public health spending for improving the health outcome.


The Genomic Landscape Of Cutaneous Scc Reveals Drivers And A Novel Azathioprine Associated Mutational Signature., Gareth J. Inman, Jun Wang, Ai Nagano, Ludmil B. Alexandrov, Karin J. Purdie, Richard G. Taylor, Victoria Sherwood, Jason Thomson, Sarah Hogan, Lindsay C. Spender, Andrew P. South, Michael Stratton, Claude Chelala, Catherine A. Harwood, Charlotte M. Proby, Irene M. Leigh Dec 2018

The Genomic Landscape Of Cutaneous Scc Reveals Drivers And A Novel Azathioprine Associated Mutational Signature., Gareth J. Inman, Jun Wang, Ai Nagano, Ludmil B. Alexandrov, Karin J. Purdie, Richard G. Taylor, Victoria Sherwood, Jason Thomson, Sarah Hogan, Lindsay C. Spender, Andrew P. South, Michael Stratton, Claude Chelala, Catherine A. Harwood, Charlotte M. Proby, Irene M. Leigh

Department of Dermatology and Cutaneous Biology Faculty Papers

Cutaneous squamous cell carcinoma (cSCC) has a high tumour mutational burden (50 mutations per megabase DNA pair). Here, we combine whole-exome analyses from 40 primary cSCC tumours, comprising 20 well-differentiated and 20 moderately/poorly differentiated tumours, with accompanying clinical data from a longitudinal study of immunosuppressed and immunocompetent patients and integrate this analysis with independent gene expression studies. We identify commonly mutated genes, copy number changes and altered pathways and processes. Comparisons with tumour differentiation status suggest events which may drive disease progression. Mutational signature analysis reveals the presence of a novel signature (signature 32), whose incidence correlates with chronic exposure …


The Dermatologist And Color, Andrzej Grzybowski, Lawrence Charles Parish Dec 2018

The Dermatologist And Color, Andrzej Grzybowski, Lawrence Charles Parish

Department of Dermatology and Cutaneous Biology Faculty Papers

The idea for an issue on color and the skin was initiated by the 2017 exhibit “Breathing Color” that had been created by the new Design Museum in London, England. While variations in color may play a significant role in diagnosing a skin disease, little attention has been directed towards the influence that color may be used to identify a dermatologic disease and even monitor a therapeutic agent. The reader need only to recall how early dermatology atlases were hand colored to provide a more realistic picture of a disease.


What's In A Name? The Impact Of Subcategory Salience On Value Perception And Upgrade Intention For Multicategory Products, Jin K. Han, Seh-Woong Chung, Yong Seok Sohn Dec 2018

What's In A Name? The Impact Of Subcategory Salience On Value Perception And Upgrade Intention For Multicategory Products, Jin K. Han, Seh-Woong Chung, Yong Seok Sohn

Research Collection Lee Kong Chian School Of Business

Despite many convergence products rapidly approaching market saturation, academic research yet lags behind with the focus still on the primary demand in the introduction stage. The authors close this gap by focusing on how the labeling of convergence products may impact on value perception and upgrade intentions for these products. Convergence products, which combine multiple categories of products into a single device, create a unique naming dilemma for manufacturers and retailers: Whether to opt for (a) a subordinate label—a lower‐level descriptor or name that embodies its subcategory elements (e.g., smartphone or Apple’s iPhone) or (b) a superordinate label—a higher‐level descriptor …


Transportation For An Aging Population: Promoting Mobility And Equity For Low-Income Seniors, Anastasia Loukaitou-Sideris, Martin Wachs, Lené Levy-Storms, Madeline Brozen Dec 2018

Transportation For An Aging Population: Promoting Mobility And Equity For Low-Income Seniors, Anastasia Loukaitou-Sideris, Martin Wachs, Lené Levy-Storms, Madeline Brozen

Mineta Transportation Institute

This study explores the travel patterns, needs, and mobility problems faced by diverse low-income, inner-city older adults in Los Angeles in order to identify solutions to their mobility challenges. The study draws information from: (1) a systematic literature review of the travel patterns of older adults; (2) a review of municipal policies and services geared toward older adult mobility in six cities; (3) a quantitative analysis of the mobility patterns of older adults in California using the California Household Travel Survey; and (4) empirical work with 81 older adults residing in and around Los Angeles’ inner-city Westlake neighborhood, who participated …


Surgical Treatment For Tubular Colonic Duplication Communicating To Retroperitoneal Space In An Adult Dog, Nithida Boonwittaya, Piyathip Choochalermporn, Sunee Kunakornsawat, Teerapol Sirinarumitr Dec 2018

Surgical Treatment For Tubular Colonic Duplication Communicating To Retroperitoneal Space In An Adult Dog, Nithida Boonwittaya, Piyathip Choochalermporn, Sunee Kunakornsawat, Teerapol Sirinarumitr

The Thai Journal of Veterinary Medicine

Canine colonic duplication is a rare congenital anomaly, usually symptomatic in the first year of life, with the common signs of bowel obstruction. Most importantly, colonic duplication in an adult dog has not been reported. This case document reports a non-communicating tubular colonic duplication with concurrent retroperitoneal mass in a 3- year-old female crossbred dog, presented for further diagnosis and treatment of the abdominal mass. Without any remarkable clinical signs, physical examination noted only abdominal distension with mild discomfort. Ultrasonography demonstrated a large mass in the mid-caudal abdomen, a tubular mass appearance on the colonic wall and the presence of …


Ophthalmology Snapshot, Nalinee Tuntivanich Dec 2018

Ophthalmology Snapshot, Nalinee Tuntivanich

The Thai Journal of Veterinary Medicine

A 6-month-old French Bulldog had been presented with left eye blepharospasm. The puppy had been treated with topical antibiotics for weeks from the local veterinarian. However, blepharospasm still persisted. Ophthalmic examination from distance showed mild conjunctival hyperemia. Excessive tear was observed around the eyeball. Close ophthalmic examinations revealed prominent conjunctival blood vessels at the outer portion of the nictitating membrane. Clump of abnormal hairs were identified at the ventro-nasal region of the palpebral conjunctiva, next to eyelid margin. Schirmer tear test 1 level of the left eye was 25 mm wetness, while it was 16 on the right.


Development And Validation Of Hybrid Continuum/Structural Finite Element Model For Evaluating Foot And Ankle Biomechanics, Saif Alrafeek Dec 2018

Development And Validation Of Hybrid Continuum/Structural Finite Element Model For Evaluating Foot And Ankle Biomechanics, Saif Alrafeek

Dissertations

Bone is composed of two structures: compact bone and spongy bone. Spongy bone porosity highly affects the strength and the physical endurance of bone to carry loads. Most studies use continuum finite element (FE) approaches to model spongy bone and neglect porosity. Neglecting porosity may not efficiently assist orthopaedic surgeons to treat patients who experience bone physical disability. The purpose of this study is to demonstrate an inexpensive approach that simulates spongy bone with more accurate capturing of porosity and less requirements of bone information. The approach is developed through investigating the mechanical characteristics of spongy bone; that is, by …


Assessing The Supports And Variables Needed For Graduation Of Students Receiving Special Education Service: A Longitudinal Study, Jennifer Dewaard Dec 2018

Assessing The Supports And Variables Needed For Graduation Of Students Receiving Special Education Service: A Longitudinal Study, Jennifer Dewaard

Dissertations

Graduation from high school is an important measure of success for both schools and individuals. While requirements for graduation change, the rate at which students receive a diploma within four years is on the rise. But students who receive special education services continue to have a lower graduation rate than the general population. It is imperative for both schools and individual students to increase this rate and close the gap for those receiving a diploma.

The purpose of this study is to examine that gap between graduation rates for the total population of a high school in West Michigan compared …


Vision-Based Framework For Monitoring Of Eating Behavior Of Persons With Alzheimer’S Disease, Haitham Al-Anssari Dec 2018

Vision-Based Framework For Monitoring Of Eating Behavior Of Persons With Alzheimer’S Disease, Haitham Al-Anssari

Dissertations

Dementia is a syndrome used to describe an array of significant declines in cognitive abilities due to progressive and irreversible loss of neurons and brain functioning. This neurodegeneration seriously affects daily life activities like driving, shopping, working and speaking. Among these, Alzheimer’s disease is the most common type of dementia, with individuals experiencing loss of memory and thinking and reasoning skills. Due to cognitive decline, individuals with Alzheimer’s often suffer from malnutrition, since they do not eat, even when food is presented, and must be fed with assistance. This assistance presents a significant burden of time to caregivers, and consequently …


Stakeholder Perspectives: Implementation Of Local School Wellness Policies In The Kent Intermediate School District, Adrienne A. Wallace Dec 2018

Stakeholder Perspectives: Implementation Of Local School Wellness Policies In The Kent Intermediate School District, Adrienne A. Wallace

Dissertations

The purpose of this study was to explore attitudes and perception of stakeholders (teachers, principals, nutrition service directors, nutrition service supervisors, school nurses, nutrition specialists and administrators) toward the implementation of the local school wellness policy in public schools within Kent County, Michigan. The subjects of interest were stakeholders from more than 300 schools and 20 public school districts within the Kent Intermediate School District. Subjects responded to a survey assessing their perspectives regarding the implementation of the local school wellness policy pursuant to the Healthy Hunger-Free Kids Act of 2010 an Obama-era policy, the results were then examined using …


Preventing Sexual Victimization: An Assertiveness Training Program For Female Adolescents, Emily Morgan Dec 2018

Preventing Sexual Victimization: An Assertiveness Training Program For Female Adolescents, Emily Morgan

Dissertations

Unwanted sexual experiences occur too frequently in the United States and result in myriad deleterious consequences. The first instances of unwanted sexual experiences for females most frequently occur during adolescence (ages 12 to 17). Despite this, the majority of literature on sexual victimization and victimization prevention programs focus on college-aged females, thus leaving a need for research on prevention programs for adolescent females. The present study examined the effects of an assertiveness training program on the risk for sexual coercion among adolescent females. A behavioral skills training model (i.e. instruction, model, rehearsal, and feedback) was used to teach seven adolescent …


Study Of Three Potential Variables That May Impact The Maximum Shear Force And Shear Variation During The Growth And Transport Of Mixed Sex Broilers Grown In Commercial Poultry Houses, Mark Christie Dec 2018

Study Of Three Potential Variables That May Impact The Maximum Shear Force And Shear Variation During The Growth And Transport Of Mixed Sex Broilers Grown In Commercial Poultry Houses, Mark Christie

Graduate Theses and Dissertations

Temperature conditions during the transportation to the processing facility of commercial broilers have a direct impact on the meat texture, specifically maximum shear force and shear variation of cooked breast meat. Analysis of a calendar year of flock data (N=346), reveals that the largest impact of transport conditions, specifically temperature, is on the standard deviation of the flocks range of cooked shear values. The optimal transport temperature that yields broiler breast meat with average flock minimum shear and standard deviation values is approximately 60°F. The shear values for flocks at or near 60°F are on average 1 kg less than …


Evolutionary Dynamics Of Brown Treesnake (Boiga Irregularis) Reproductive Ecology, With Implications For Invasive Species Control, Brenna Aaren Levine Dec 2018

Evolutionary Dynamics Of Brown Treesnake (Boiga Irregularis) Reproductive Ecology, With Implications For Invasive Species Control, Brenna Aaren Levine

Graduate Theses and Dissertations

Invasive species represent major threats to biodiversity, global economies, and human health. Consequently, extensive research has been directed towards improving methods that restrict and contain them. Yet, control measures can also act as agents of selection by significantly impacting the reproductive capacity of invasives (in the context of “eco-evo” dynamics). The end result is that control measures subsequently alter the fitness landscape of an invasive over ecologically-relevant time, and lose their efficacy by so doing. However, adaptive management can be promoted by investigating the relationships between reproductive ecology, strength of selection, and (additive) genetic variation. In short, effective control can …


The Impact Of Transfer Shock In A Dental Hygiene Program At A Four-Year Health-Sciences University, Claire Sallee Tucker Dec 2018

The Impact Of Transfer Shock In A Dental Hygiene Program At A Four-Year Health-Sciences University, Claire Sallee Tucker

Graduate Theses and Dissertations

In order for a student to be successful in dental hygiene education, the student must gain the required knowledge and skills necessary to perform as a hygienist and possess the ability to utilize critical thinking to apply these attributes while in the program and on the National Board of Dental Hygiene Examination (NBDHE) (Alzahrani, Thompson, & Bauman, 2007; Fried, Maxey, Battani, Gurenlian, Byrd, & Brunick, 2017). Dental hygiene students who attend a medical university have the option to take required pre-requisite courses at a community college or a four-year university. All dental hygiene students transfer from another institution and all …


The Effect Of Dehydration On Metabolism And Energy Substrate Utilization, Zachary Robert Lewis Dec 2018

The Effect Of Dehydration On Metabolism And Energy Substrate Utilization, Zachary Robert Lewis

Graduate Theses and Dissertations

The purpose of this study was to measure hormonal and metabolic markers in humans to see if simulating dehydration would emulate measures that are seen in prediabetic humans. 60 volunteers were divided into equal categories by sex and body mass index of normal or overweight. Participants completed two oral glucose tolerance tests (OGTT) after being intravenously infused with a isotonic or hypertonic saline solution for 120 minutes in a counter balanced order. All trials began with a euhydrated subject with a urine specific gravity (USG)


Impedance Sensing Of Cancer Cells Directly On Sensory Bioscaffolds Of Bioceramics Nanofibers, Hanan Alismail Dec 2018

Impedance Sensing Of Cancer Cells Directly On Sensory Bioscaffolds Of Bioceramics Nanofibers, Hanan Alismail

Graduate Theses and Dissertations

Cancer cell research has been growing for decades. In the field of cancer pathology, there is an increasing and long-unmet need to develop a new technology for low-cost, rapid, sensitive, selective, label-free (i.e. direct), simple and reliable screening, diagnosis, and monitoring of live cancer and normal cells in same shape and size from the same anatomic region. For the first time on using an impedance signal, the breast cancer and normal cells have been thus screened, diagnosed and monitored on a smart bioscaffold of entangled nanowires of bioceramics titanate grown directly on the surface of implantable Ti-metal and characterized by …


Quantitative Microbial Risk Assessment For Parts, Ground, And Msc Poultry Product Including Intervention Analysis And Exploration Of Enterobacteriaceae As An Indicator Organism In Poultry Processing, Leigh Ann Parette Dec 2018

Quantitative Microbial Risk Assessment For Parts, Ground, And Msc Poultry Product Including Intervention Analysis And Exploration Of Enterobacteriaceae As An Indicator Organism In Poultry Processing, Leigh Ann Parette

Graduate Theses and Dissertations

Samples collected at five different large bird poultry processing facilities over a period of 7 months from prescald to post debone locations were enumerated for Enterobacteriaceae, Salmonella spp., and Campylobacter spp. and the results were used to create Quantitative Microbial Risk Analyses (QMRA) models for parts, ground, and mechanically separated chicken (MSC) products. Sensitivity analyses indicated the points in the process at which reductions would be most advantageous to the endpoint and simulation models were run to test reductions required to meet the current USDA performance standards.

These data were analyzed to determine the reductions from one node (location) to …


Ca2+ - Induced Structural Change Of Multi-Domain Collagen Binding Segments Of Collagenases Colg And Colh From Hathewaya Histolytica, Christopher Eric Ruth Dec 2018

Ca2+ - Induced Structural Change Of Multi-Domain Collagen Binding Segments Of Collagenases Colg And Colh From Hathewaya Histolytica, Christopher Eric Ruth

Graduate Theses and Dissertations

Hathewaya histolytica, previously renamed as Clostridium histolyticum, secretes at least two collagenases, ColH and ColG, that allow for degradation of extracellular matrices of animal tissue. Hathewaya histolytica virulence factors are proposed to undergo domain rearrangement upon secretion from the bacteria to the host. In order to accomplish this, collagenases seek the least ordered regions in collagen to efficiently disassemble the fibril. Two types of domains, Polycystic Kidney Disease-like (PKD) and Collagen Binding Domain (CBD), direct the collagenases ability to disassemble the fibril. Calcium dependent structural change have been reported to increase in thermal stability and in tighter collagen binding for …


Intelligent Application Of Flexible Ac Transmission System Components In An Evolving Power Grid, Robert Wall Dec 2018

Intelligent Application Of Flexible Ac Transmission System Components In An Evolving Power Grid, Robert Wall

Graduate Theses and Dissertations

The world revolves around energy and the energy sector is continually transforming and evolving. The status quo has been set by governing agencies in the United States for completely reliable power. The demand for energy efficiency continually rises for multiple reasons. Technology has improved for all sectors of the power grid, including renewable energy sources, fault protection, and SMART grid technology. The addition of new energy sources has led to the decommissioning of inefficient energy sources. The implementation of new technologies and power load on a large scale, coupled with the removal of grid stabilizers has posed different challenges that …


Impact Of Roadside Maintenance Practices On Larinus Minutus (Gyllenhal), A Biological Control Agent Of Spotted Knapweed, Mary Elizabeth Ferguson Dec 2018

Impact Of Roadside Maintenance Practices On Larinus Minutus (Gyllenhal), A Biological Control Agent Of Spotted Knapweed, Mary Elizabeth Ferguson

Graduate Theses and Dissertations

Spotted knapweed, Centaurea stoebe, is an invasive weed found throughout much of the United States. Spotted knapweed is a rangeland weed where it was originally introduced into western North America in the 1880s.Where spotted knapweed spread to the southeastern U.S., it is found mostly along roadsides. It has been the focus of a biological control program beginning in the 1960s, with 12 insects established, with the final introductions occurring in the 1990s. After the success observed in the western U.S. and Canada with one of these insects, Larinus minutus, this weevil was established in northwestern Arkansas. It is too early …


Morphological Features Of Dysplastic Progression In Epithelium: Quantification Of Cytological, Microendoscopic, And Second Harmonic Generation Images, Sandra Patricia Gordon Dec 2018

Morphological Features Of Dysplastic Progression In Epithelium: Quantification Of Cytological, Microendoscopic, And Second Harmonic Generation Images, Sandra Patricia Gordon

Graduate Theses and Dissertations

Advances in imaging technology have led to a variety of available clinical and investigational systems. In this collection of studies, we tested the relevance of morphological image feature quantification on several imaging systems and epithelial tissues. Quantification carries the benefit of creating numerical baselines and thresholds of healthy and abnormal tissues, to potentially aid clinicians in determining a diagnosis, as well as providing researchers with standardized, unbiased results for future dissemination and comparison.

Morphological image features in proflavine stained oral cells were compared qualitatively to traditional Giemsa stained cells, and then we quantified the nuclear to cytoplasm ratio. We determined …