Digital Commons Network^™

Evaluasi Pengetahuan Dan Persepsi Obat Batuk Swamedikasi Oleh Perokok, Amelia Lorensia, Ananta Yudiarso, Rizkia Arrahmah

Media Kesehatan Masyarakat Indonesia

Coughing is one of the most common symptoms in smokers. Smokers who experience a lot of cough are
caused by exposure to cigarette smoke that enters the respiratory tract. The purpose of this study was to determine
how smokers perceive symptoms of cough, use of cough medicine, and self-medication services performed by pharmacists.
This study began in March to July 2016. This study used the mixed method method that uses sequential
explanatory research design. The research sample involved amounted to 100 people, and 12 studies conducted
for interviews were conducted to obtain supporting data. The sample were active smokers aged …

Pengaruh Pemberian Susu Tinggi Protein Terhadap Tingkat Nafsu Makan Dan Kadar Glukosa Postprandial, Harna Harna, Clara M.Kusharto, Katrin Roosita, Andi Muh Asrul Irawan

Media Kesehatan Masyarakat Indonesia

High protein milk is a complex food that contains several potential bioactive compounds that might effect
on appetite control. However, the mechanism of high protein milk effect on appetite is still poorly understood in
underweight adults. This study aimed to analyze the effect of high protein milk on appetite level and postprandial
glucose. This study used experimental trial with design randomized controlled trial. The subjects were divided into
two groups, 24 subjects in the treatment group and 23 subjects in the control group. Treatment group was given
high protein milk and control group was given glucose. Subjective feelings including hunger, …

Efektivitas Cbia-Narkoba Dalam Peningkatan Pengetahuan Remaja Untuk Menolak Narkoba, Sinta Rachmawati, Sri Suryawati, Rustamaji Rustamaji

Media Kesehatan Masyarakat Indonesia

Drug abuse is still a major health problem in Indonesia. The lecture method is one of the most widely used
to provide information, including drug. CBIA (Community Based Interactive Approach) drug is an alternative
educational method that involves small group discussion. This study aims to assess the effectiveness of CBIA-Drug
compared with lecture method in improving youth knowledge to resist drug. Quasi experimental with pre test-post
test control group design was used in this study. It involved 30 respondents for CBIA-Drug group, 30 respondents
for intervention group and 30 respondents for control group. Mutivariate statistical analysis (kruskall wallis)
was used …

Apakah Status Akreditasi Rumah Sakit Memberikan Perbedaan Pemberian Obat Yang Benar Dan Keselamatan Pasien?, Saptono Putro, Viera Wardhani, Siswanto Siswanto

Media Kesehatan Masyarakat Indonesia

Hospital accreditation provides guidelines for implementing quality management standards including drug
management management to reduce the incidence of patient safety (IPS). This study aims to determine the difference
between the right implementation of drug administration and the perceieved of IPS based on hospital accreditation
status. This researchusing a survey method with cross sectional analytical approach, which compares the
correct implementation of the drug and IKP perception in 2 type D hospitals with different accreditation status in
the Greater Malang area. Measurements of the correct implementation of drug administration and IKP perceptions
were carried out using a closed questionnaire on 36 …

Using Physical Contact Heterogeneity And Frequency To Characterize Dynamics Of Human Exposure To Nonhuman Primate Bodily Fluids In Central Africa, Victor Narat, Mamdou Kampo, Thibut Heyer, Stephanie Rupp, Philippe Ambata, Richard Njouom, Tamara Giles-Vernick

Publications and Research

Emerging infectious diseases of zoonotic origin constitute a recurrent threat to global health. Nonhuman primates (NHPs) occupy an important place in zoonotic spillovers (pathogenic transmissions from animals to humans), serving as reservoirs or amplifiers of multiple neglected tropical diseases, including viral hemorrhagic fevers and arboviruses, parasites and bacteria, as well as retroviruses (simian foamy virus, PTLV) that are pathogenic in human beings. Hunting and butchering studies in Africa characterize at-risk human social groups, but overlook critical factors of contact heterogeneity and frequency, NHP species differences, and meat processing practices. In southeastern Cameroon, a region with a history of zoonotic emergence …

Pharmacy-Based Travel Health Services In The United States, Keri Hurley-Kim, Jeffery Goad, Sheila Seed, Karl M. Hess

Pharmacy Faculty Articles and Research

The aim of this paper is to review pharmacy laws and regulations, pharmacist training, clinic considerations, and patient care outcomes regarding pharmacy-based travel health services in the United States. Pharmacists and pharmacies in the United States are highly visible and accessible to the public, and have long been regarded as a source for immunization services. As international travel continues to increase and grow in popularity in this country, there is a pressing need for expanded access to preventative health services, including routine and travel vaccinations, as well as medications for prophylaxis or self-treatment of conditions that may be acquired overseas. …

The Weekly Challenger, December 27, 2018, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The December 27, 2018, issue of The Weekly Challenger.

A Review Of Beneficial Low-Intensity Exercises In Diabetic Peripheral Neuropathy Patients, Carley Johnson, Jody K. Takemoto

Pharmacy Faculty Publications and Presentations

The American Diabetic Association standards of medical care for diabetic patients recommends moderate intensity exercise to help manage diabetes; however, this recommendation may be unmanageable for patients who have become inactive or unable to reach this intensity. The purpose of this review is to determine if low-intensity exercises demonstrate improvement in diabetic peripheral neuropathy symptoms in order to utilize these exercises as a starting point for inactive patients. Studies in low-intensity exercises from 2013 to May 2018 were systematically searched in PubMed, SCOPUS, and Cochrane Library databases. The studies in this research have shown that low-intensity resistance exercises have promising …

Small Rna Mgrr Regulates Sensitivity Of Escherichia Fergusonii To Oxidative Stress, Austin Paul Wright

Dissertations and Theses

Non-coding small RNAs (sRNAs) are integral to post-transcriptional gene regulation in bacteria. The function of an sRNA is dependent on both secondary structure and the sequence of its unstructured seed region. The sRNA seed region typically base-pairs with target mRNAs to down-regulate the expression of target genes by blocking the ribosome-binding site or by promoting RNase-mediated degradation of the sRNA-mRNA complex. sRNAs have also been shown to increase expression of target genes by releasing RNA secondary structures that block ribosome-binding sites. Selective pressure to maintain sRNA function conserves the sequence of the sRNA seed region, but mutations in mRNA sequences …

In Situ Gel Of Triamcinolone Acetonide-Loaded Solid Lipid Nanoparticles For Improved Topical Ocular Delivery: Tear Kinetics And Ocular Disposition Studies, Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Sai Prachetan Balguri, Bharathi Avula, Monica M. Jablonski, Soumyajit Majumdar

Faculty and Student Publications (Open Access)

Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular edema. The objective of this investigation was to prepare TA-loaded solid lipid nanoparticles (TA-SLNs) and in situ gel (TA-SLN-IG) formulations for delivery into the deeper ocular tissues through the topical route. TA-SLNs were prepared by hot homogenization and ultrasonication method using glyceryl monostearate and Compritol® 888ATO as solid lipids and Tween®80 and Pluronic® F-68 as surfactants. TA-SLNs were optimized and converted to TA-SLN-IG by the inclusion of gellan gum and evaluated for their rheological properties. In …

State V. Salinas Appellant's Brief Dckt. 46227

Not Reported

No abstract provided.

Multigenerational Consequences Of Early-Life Cannabinoid Exposure In Zebrafish, Dennis Carty, Zachary S. Miller, Cammi Thornton, Zacharias Pandelides, Marisa L. Kutchma, Kristine L. Willett

Faculty and Student Publications (Open Access)

No abstract provided.

Interpersonal Violence In Peacetime Malawi., Rebecca G. Maine, Brittney Williams, Jennifer A. Kincaid, Gift Mulima, Carlos Varela, Jared R. Gallaher, Trista D. Reid, Anthony G. Charles

Department of Surgery Faculty Papers

Background: The contribution of interpersonal violence (IPV) to trauma burden varies greatly by region. The high rates of IPV in sub-Saharan Africa are thought to relate in part to the high rates of collective violence. Malawi, a country with no history of internal collective violence, provides an excellent setting to evaluate whether collective violence drives the high rates of IPV in this region.

Methods: This is a retrospective review of a prospective trauma registry from 2009 through 2016 at Kamuzu Central Hospital in Lilongwe, Malawi. Adult (>16 years) victims of IPV were compared with non-intentional trauma victims. Log binomial …

The Addition Of Simvastatin Administration To Cold Storage Solution Of Explanted Whole Liver Grafts For Facing Ischemia/Reperfusion Injury In An Area With A Low Rate Of Deceased Donation: A Monocentric Randomized Controlled Double-Blinded Phase 2 Study., Duilio Pagano, Elisabetta Oliva, Simone Khouzam, Fabio Tuzzolino, Davide Cintorino, Sergio Li Petri, Fabrizio Di Francesco, Calogero Ricotta, Pasquale Bonsignore, Alessandro Tropea, Sergio Calamia, Federico Costanzo, Angelo Luca, Salvatore Gruttadauria

Student Papers, Posters & Projects

BACKGROUND: Liver transplantation is the best treatment for end-stage liver disease. The interruption of the blood supply to the donor liver during cold storage damages the liver, affecting how well the liver will function after transplant. The drug Simvastatin may help to protect donor livers against this damage and improve outcomes for transplant recipients. The aim of this study is to evaluate the benefits of treating the donor liver with Simvastatin compared with the standard transplant procedure.

PATIENT AND METHODS: We propose a prospective, double-blinded, randomized phase 2 study of 2 parallel groups of eligible adult patients. We will compare …

Breast Injury During Sport Participation, Laura J. Smith, Tamara Eichelberger, Elizabeth Miller, Edward J Kane

Athletic Training Collection

A recent study found that almost half (47.9%), of female college athletes participating in basketball, soccer, volleyball and softball (n = 194) suffered a breast injury during their college career with less than 10% reporting their injury to health personnel with only 2.1% receiving treatment ^[1]. Breast injury in female athletes is under-reported and is lacking a much-needed level of awareness in sport. If there is a void in awareness of breast injuries and in reporting breast injuries, preventive measures as well as any potential sequela from the injury will not be given the necessary attention.

Capsule Integrated Polypeptide Multilayer Films For Effective Ph-Responsive Multiple Drug Co-Delivery, Shichao Zhang, Malcolm Xing, Bingyun Li

Clinical and Translational Science Institute

Many applications using drug-carrying biomedical materials require on-demand, localized delivery of multiple therapeutic agents in precisely controlled and patient-specific time sequences, especially after assembly of the delivery vehicles; however, creating such materials has proven extremely challenging. Here, we report a novel strategy to create polypeptide multilayer films integrated with capsules as vehicles for co-delivery of multiple drugs using layer-bylayer self-assembly technology. Our approach allows the multilayered polypeptide nanofilms and preimpregnated capsules to assemble into innovative biomedical materials with high and controllable loading of multiple drugs at any time postpreparation and to achieve pH-responsive and sustained release. The resulting capsule-integrated polypeptide …

Pulmonary Toxicity And Lung Tumorigenic Potential Of Surrogate Metal Oxides In Gas Metal Arc Welding–Stainless Steel Fume: Iron As A Primary Mediator Versus Chromium And Nickel, Lauryn M. Falcone, Aaron Erdely, Rebecca Salmen, Michael Keane, Lori Battelli, Vamsi Kodali, Aleksandr B. Stefaniak, Michael L. Kashon, James M. Antonini, Patti C. Zeidler-Erdely

Faculty & Staff Scholarship

In 2017, the International Agency for Research on Cancer classified welding fumes as “car- cinogenic to humans” (Group 1). Both mild steel (MS) welding, where fumes lack carcino- genic chromium and nickel, and stainless steel (SS) increase lung cancer risk in welders; therefore, further research to better understand the toxicity of the individual metals is needed. The objectives were to (1) compare the pulmonary toxicity of chromium (as Cr(III) oxide [Cr2O3] and Cr (VI) calcium chromate [CaCrO4]), nickel [II] oxide (NiO), iron [III] oxide (Fe2O3), and gas metal arc welding-SS (GMAW-SS) fume; and (2) determine if these metal oxides can …

Disparities In Social Determinants Of Health Outcomes And Behaviours Between Older Adults In Alaska And The Contiguous Us: Evidence From A National Survey, Steven A. Cohen, Ana X. Talamas, Natalie J. Sabik

Public Health Faculty Publications

Few studies have focused on understanding how sociodemographic factors impact healthy ageing in the rapidly growing population of Alaskan older adults. Therefore, the objectives of this study are to compare the health of Alaskan older adults to those in the contiguous US, and determine how the associations differ between older adults in Alaska and the contiguous US. We abstracted 165,295 respondents age 65+ from the 2016 Behavioral Risk Factor Surveillance System. We used generalised linear models to assess the associations between sociodemographic factors and six health outcomes accounting for confounders and complex sampling. In the contiguous US, females were less …

The Impact Of Hurricane Matthew On School Attendance: An Analysis From Rural Haiti, Amanda C. Cook, Donovan Beachy

Economics Faculty Publications

This study identifies the impact of Hurricane Matthew on school attendance in an agricultural community in rural Haiti. We conducted a survey of parents whose children attended a rural school prior to Hurricane Matthew to determine the mechanism by which hurricanes impact school attendance. We determined the marginal effect of family size and school enrollment using a probit model. Parents identified two primary causes for their children leaving school: a loss of income—through crop damage and livestock deaths—and requiring the children’s labor on the family farm. In our sample 96 children, 46% of the children enrolled in school, stopped attending …

A Closer Look At The Items Within Three Measures Of Evolution Acceptance: Analysis Of The Mate, I-Sea, And Gaene As A Single Corpus Of Items, William L. Romine, Amber Todd, Emily M. Walter

Medical Education Faculty Publications

Background: Current direct Likert measures for evolution acceptance include the MATE, GAENE, and I-SEA. Pros and cons of each of these instruments have been debated, and yet there is a dearth of research teasing out their similarities and differences when they are used together in a single context beyond the fact that their measures tend to be highly correlated. We administered these to 452 college students in non-major biology classes at two research-intensive universities from the Midwestern and Western United States to investigate the measurement properties of the items within these instruments when combined as a single corpus.Results: Factor analysis …

Hematopoietic Stem And Progenitor Cells Are A Distinct Hiv Reservoir That Contributes To Persistent Viremia In Suppressed Patients, Thomas D. Zaikos, Valeri H. Terry, Nadia T. Sebastian Kettinger, Jay Lubow, Mark M. Painter, Maria C. Virgilio, Andrew Neevel, Frances Taschuk, Adewunmi Onafuwa-Nuga, Lucy A. Mcnamara, James Riddell, Dale Bixby, Norman Markowitz, Kathleen L. Collins

Infectious Diseases Articles

Long-lived reservoirs of persistent HIV are a major barrier to a cure. CD4+ hematopoietic stem and progenitor cells (HSPCs) have the capacity for lifelong survival, self-renewal, and the generation of daughter cells. Recent evidence shows that they are also susceptible to HIV infection in vitro and in vivo. Whether HSPCs harbor infectious virus or contribute to plasma virus (PV) is unknown. Here, we provide strong evidence that clusters of identical proviruses from HSPCs and their likely progeny often match residual PV. A higher proportion of these sequences match residual PV than proviral genomes from bone marrow and peripheral blood mononuclear …

Phenotypic And Transcriptomic Characterization Of Colonial Phase Variation In The Cholera Pathogen Reveals A Novel Smooth Biofilm-Defective Form, Bliss Nicole Lambert

LSU Doctoral Dissertations

Biofilm formation, through the production of Vibrio polysaccharide (VPS), greatly enhances the environmental fitness and pathogenic success of Vibrio cholerae. As a result of phase variation, V. cholerae can switch from a smooth form to rugose, whose cells produce excess VPS, resulting in highly structured biofilms and greater resistance to stress. To further characterize the reversible process of phase variation, we isolated three colonial lineages. Each lineage began with a smooth parent, N16961, and contained a rugose variant derived from the parent, N16961R, as well as a smooth revertant of the rugose, N16961SD. We found clear phenotypic and transcriptomic …

Climatic Assessment Of The Chemical Properties Of Surface Water In Dhi Qar Governorate, Climatic Assessment Of The Chemical Properties Of Surface Water In Thi Qar Governorate, Abdul Imam Nassar Dery

Uruk Journal of Human Sciences

The paper includes chemical characteristics of waters of the Euphrates river, Shatt Al Gharraf and the marshes of both (Chabaish, Abu Zark, Al- Adil, and Al-Sanaf) in July and January for the period between 2017-2018. The results of the study have shown that moral differences existed in the chemical characteristics in all study stations. It also shows that the concentrations of water pollutants rise above the levels and exceeded health determinants permitted by the World Health Organization. The existence of a variation has also exhibited plainly and most concentrations of chemical characteristics rise during July as well.

Understanding Urbanization: A Study Of Census And Satellite-Derived Urban Classes In The United States, 1990-2010, Deborah Balk, Stefan Leyk, Bryan Jones, Mark R. Montgomery, Anastasia Clark

Publications and Research

Most of future population growth will take place in the world’s cities and towns. Yet, there is no well-established, consistent way to measure either urban land or people. Even censusbased urban concepts and measures undergo frequent revision, impeding rigorous comparisons over time and place. This study presents a new spatial approach to derive consistent urban proxies for the US. It compares census-designated urban blocks with proxies for landbased classifications of built-up areas derived from time-series of the Global Human Settlement Layer (GHSL) for 1990–2010. This comparison provides a new way to understand urban structure and its changes: Most land that …

Online Learning Checkpoints: Exploring The Role Of Mandatory Student And Ta Interaction And Perceptions Of Satisfaction And Usefulness, Carolyn Andrews

Instructional Psychology and Technology Graduate Student Projects

With the rapid growth of online learning, there is considerable attention focused on student interaction and satisfaction in online courses. Instructors are instrumental in orchestrating interaction. When interaction is dissected, three distinct functions are identified. Researchers have identified T.A.’s as capable of fulfilling some of these instructor functions. TA’s from Brigham Young University’s online program conduct 3 predetermined checkpoints with each of their students. Checkpoints are used to monitor the progress and to ensure its timely advancement. The purpose of this study is to understand the nature and effectiveness of T.A. - student checkpoint interactions. Specifically, this research seeks to …

High Affinity Binding Of H3k14ac Through Collaboration Of Bromodomains 2, 4 And 5 Is Critical For The Molecular And Tumor Suppressor Functions Of Pbrm1., Lili Liao, Nilda L. Alicea-Velázquez, Lauren Langbein, Xiaohua Niu, Weijia Cai, Eun-Ah Cho, Meiling Zhang, Celeste B. Greer, Qin Yan, Michael S. Cosgrove, Haifeng Yang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Polybromo-1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl-lysine residues. While BD2 has been found to bind acetylated histone H3 lysine 14 (H3K14ac), it is not known whether other BDs collaborate with BD2 to generate strong binding to H3K14ac, and the importance of H3K14ac recognition for the molecular and tumor suppressor function of PBRM1 is also unknown. We discovered that full-length PBRM1, but not its individual BDs, strongly binds H3K14ac. BDs 2, 4, and 5 were found to collaborate to facilitate strong binding to H3K14ac. Quantitative …

Proteomic Analysis Discovers The Differential Expression Of Novel Proteins And Phosphoproteins In Meningioma Including Nek9, Hk2 And Set And Deregulation Of Rna Metabolism., Jemma Dunn, Sara Ferluga, Vikram Sharma, Matthias Futschik, David A. Hilton, Claire L. Adams, Edwin Lasonder, C. Oliver Hanemann

School of Biomedical Sciences

BACKGROUND: Meningioma is the most frequent primary intracranial tumour. Surgical resection remains the main therapeutic option as pharmacological intervention is hampered by poor knowledge of their proteomic signature. There is an urgent need to identify new therapeutic targets and biomarkers of meningioma. METHODS: We performed proteomic profiling of grade I, II and III frozen meningioma specimens and three normal healthy human meninges using LC-MS/MS to analyse global proteins, enriched phosphoproteins and phosphopeptides. Differential expression and functional annotation of proteins was completed using Perseus, IPA® and DAVID. We validated differential expression of proteins and phosphoproteins by Western blot on a meningioma …

Mutants Of Cocaine Esterase, Donald Landry, Chang-Guo Zhan

Pharmaceutical Sciences Faculty Patents

Provided are mutant cocaine esterase polypeptides and PEGylated formulations thereof.

The Constitution Of The Republic Of Uzbekistan – The Basis Of Improving Legislation Of Non-Governmental Non-Profit Organizations In The Implementation Of Public Ecological Control, O. Utegenov

Review of law sciences

this article is realted to particular qualities and conceptions of socio-ecological control, conclusions and offers on this problem are included.

Assessing The Legal Base For Gender Neutral Society In Uzbekistan Using Un Sustainable Development Goals Framework, R. Arslonova

Review of law sciences

This article critically analyzes existing legal framework with respect to protecting women’s right; substantiating their equal status in society; creating new opportunities to promote better equality between men and women. Author researches UN Sustainable Development Goals framework with the intention of compiling a roadmap to further the agenda on women’s rights in Uzbekistan with global perspective.