Digital Commons Network^™

Creating Sustainable Industrial Building In China By Lowering Energy Use And Improving The Working Environment, Wenjie Hu

Theses

Over 70% of energy in China is consumed by industrial buildings and related support activities. In order to reduce production costs, owners of factories tend to pay little attention to protecting the environment or workers’ health, causing many serious consequences. Poorly designed buildings require more energy to operate and are less energy efficient to maintain. A lack of natural lighting results in more energy consumption for interior illumination, and improper fenestration design requires more energy to keep buildings cool. An uncomfortable working environment will affect the working efficiency and physical health of the labor force. In this thesis, two simple, …

A Sliver Of Light, Melissa Browning

A Midwestern Review: A Magazine of the Arts and Issues at DePauw University

No abstract provided.

The Evaluation Of Attitudes Towards Individuals With Mental Illness Among Counselors In Training, Randall Boen

Dissertations

Negative attitudes and stigma associated with mental illness have a profound impact on individuals who experience them. Researchers have defined stigma as the attribution of a deviant characteristic to members of a particular group. Persons with severe and persistent mental illness (SPMI) face many difficulties that impact their full participation in social life. Although attitudinal reactions to individuals with SPMI have improved considerably over the last few decades, there are still areas for improvement. Limited research has been conducted to evaluate attitudes and stigma associated with individuals with SPMI among human service professionals-in-training (HSPs). For this study HSPs were defined …

The Impact Of Net Neutrality And Additional Regulations On The Future Of The Internet Of Things In The United States, Radhika Kanaskar

Honors Scholar Theses

Throughout the history of the Internet and the development of computers, commercial Internet service providers (ISPs) and independent agencies of the United States government have always controlled how consumers interact with technology. Then, in the past decade, powerful technology corporations developed new products and services that fundamentally altered society’s relationship with the Internet. The introduction of Internet of Things technology through devices such as smart speakers, smart appliances, smart cars, and wearables also contributed to the change. However, regardless of these significant advancements in technology, regulations for ISPs and technology corporations has predominately remained the same. The increased presence of …

The Role Of Required Volunteerism And Service-Learning On Student Perceptions Of Civic Responsibility, Amanda T. Beeler

Masters Theses and Doctoral Dissertations

Civic education has historically been one of the fundamental goals of U.S. higher education. However, the importance placed on teaching civic responsibility in this environment declined during the 20th century. Civic education experienced a resurgence in the 1980s, and service-learning pedagogy and other forms of community-based learning became increasingly popular. As a result, a number of high schools and institutions of higher education have implemented mandatory service programs aimed at encouraging students’ long-term engagement in community and civic activities. However, there is a dearth of research on mandatory service programs and the efficacy of requiring students to participate in community …

Expectations Of Student Achievement Among Primary School Teachers In Togo, West Africa: An Analysis Of Beliefs And Cultural Values, Andrew Paul Ward

Masters Theses and Doctoral Dissertations

The purpose of this research study was to analyze and explore the beliefs and cultural values that influence teacher expectations of student achievement in Togo, West Africa. A census was conducted of 93 teachers from the faculties of 15 Christian primary schools partnered with a U.S. based Baptist missions organization. Among partnered schools at the time of this study, teacher training in the area of expectations was often generalized due to the absence of scientific research and published data regarding teacher beliefs and expectations in West Africa. A case study approach was used with multiple data collection methods. The The …

The Role Of Music In Worship Among Deaf Culture Christianity, Mallory Ruth Dunn

Masters Theses

Throughout the Word of God, we are called to worship our Creator through music. "Shout for joy to the Lord, all the earth, burst into jubilant song with music; make music to the Lord with the harp and the sound of singing, with trumpets and the blast of the ram's horn--shout for joy before the Lord, the King" (Psalm 98: 4-6 [NIV]). It has been said that music is a universal language: but all cultures use it differently and therefore it is not a universal language but a universal phenomenon. What about the individual who cannot hear the music or …

Welfare Implications Of An Enrichment Program For Two Species Of Common Aquaria Fish, Matthew Burgess

The Plymouth Student Scientist

Public and academic interest into the welfare of captive animals is strong, and ever growing (Barrows, 2017). In accordance with this, standards of zoo and aquarium welfare science has thrived within recent years, with considerable resource spent assuring the lives of those in captivity are to an acceptable standard (Damasceno et al, 2017). Despite this, an understanding into the mechanisms which impact welfare, and the theoretical tools to assess it, require further specification (Barrows, 2017). This research assessed the welfare of two common aquaria fish, a population of regal tangs (Paracanthurus hepatus), and a population of yellow tangs (Zebrasoma flavescens). …

Do Zebrafish Exhibit A Placebo Response? Fluoxetine Conditioning In Chronically Stressed Adult Zebrafish (Danio Rerio), Kanza M. Khan

Dissertations

Placebo responses are a widely observed phenomenon in humans and animals alike. In humans, placebo responses are largely attributed to expectancy processes, and conditioning (Stewart-Williams, & Podd, 2004). In the clinical setting, the placebo response is very useful as it has the power to improve physical and/or psychological states, without the need for treatment with a higher drug dose. In clinical trials however, researchers must control for potential placebo effects. Still, despite the experimental control, placebo responses are widely observed during phase 2 and phase 3 clinical trials, resulting in a weak drug effect. In the effort to improve the …

Design Of An Attitude Control System For A Spacecraft With Propellant Slosh Dynamics, Nolan Coulter

Doctoral Dissertations and Master's Theses

The presence of propellant slosh dynamics in a spacecraft system during a maneuver leads to attitude control system (ACS) performance degradation resulting in attitude tracking errors and instability. As spacecraft missions become more complex and involve longer durations, a substantial propellant mass is required to achieve the mission objectives and perform orbital maneuvers. When the propellant tanks are only partially filled, the liquid fuel moves inside the tanks with translational and rotational accelerations generating the slosh dynamics. This research effort performs a comparative study with different optimal control techniques and a novel application of a model reference artificial immune system …

Non-Neutralizing Antibodies Elicited By Recombinant Lassa-Rabies Vaccine Are Critical For Protection Against Lassa Fever., Tiago Abreu-Mota, Katie R. Hagen, Kurt Cooper, Peter B. Jahrling, Gene Tan, Christoph Wirblich, Reed F. Johnson, Matthias J. Schnell

Department of Microbiology and Immunology Faculty Papers

Lassa fever (LF), caused by Lassa virus (LASV), is a viral hemorrhagic fever for which no approved vaccine or potent antiviral treatment is available. LF is a WHO priority disease and, together with rabies, a major health burden in West Africa. Here we present the development and characterization of an inactivated recombinant LASV and rabies vaccine candidate (LASSARAB) that expresses a codon-optimized LASV glycoprotein (coGPC) and is adjuvanted by a TLR-4 agonist (GLA-SE). LASSARAB elicits lasting humoral response against LASV and RABV in both mouse and guinea pig models, and it protects both guinea pigs and mice against LF. We …

A Virus-Encoded Type I Interferon Decoy Receptor Enables Evasion Of Host Immunity Through Cell-Surface Binding., Bruno Hernáez, Juan Manuel Alonso-Lobo, Imma Montanuy, Cornelius Fischer, Sascha Sauer, Luis J. Sigal, Noemí Sevilla, Antonio Alcamí

Department of Microbiology and Immunology Faculty Papers

Soluble cytokine decoy receptors are potent immune modulatory reagents with therapeutic applications. Some virus-encoded secreted cytokine receptors interact with glycosaminoglycans expressed at the cell surface, but the biological significance of this activity in vivo is poorly understood. Here, we show the type I interferon binding protein (IFNα/βBP) encoded by vaccinia and ectromelia viruses requires of this cell binding activity to confer full virulence to these viruses and to retain immunomodulatory activity. Expression of a variant form of the IFNα/βBP that inhibits IFN activity, but does not interact with cell surface glycosaminoglycans, results in highly attenuated viruses with a virulence similar …

Development Of Onchocerca Volvulus In Humanized Nsg Mice And Detection Of Parasite Biomarkers In Urine And Serum., John B. Patton, Sasisekhar Bennuru, Mark L. Eberhard, Jessica A. Hess Ligas, April R. Torigian, Sara Lustigman, Thomas B. Nutman, David Abraham

Department of Microbiology and Immunology Faculty Papers

BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified.

METHODOLOGY/PRINCIPAL FINDINGS: We hypothesized that highly immunodeficient NSG mice would support the survival and maturation of O. volvulus and alteration of the host microenvironment through the addition of various human cells and tissues would further enhance the level of parasite maturation. NSG mice were humanized with: (1) umbilical cord derived CD34+ stem cells, (2) fetal derived liver, …

Using Learning Express-Ways In Special Education Teacher Preparation: Developing Student-Faculty Relationships As A Path To Partnership, Heather H. Smith Ph.D., Anthony Sanchez M.A.T., Maria Peterson-Ahmad Ph.D., Christine Woodbury Ph.D., Belinda B. Mitchell Ph.D.

The Journal of Special Education Apprenticeship

This paper explores the effects of implementing Learning Express-Ways as an instructional communication tool between students and faculty in courses that are part of a special education teacher preparation program and apprenticeship. Findings suggest that using Learning Express-Ways contributed to the development of learning relationships with faculty and this instructional communication tool may be helpful in creating a partnership-focused approach in special education teacher preparation program.

The Scoop, Vol. 5 Issue 9, December 2018, Health Sciences Library

Volume 5

Latest news and events from the Health Sciences Library in our monthly newsletter for December 2018.

Local Delivery Of Mesenchymal Stem Cells Expressing Osteogenesis-Inducing Microrna For Bone Tissue Engineering Applications, Marco Antonio Arriaga

Theses and Dissertations

Bone is capable of regenerating autonomously when the injury is small (< 2.5 cm), however, large (> 2.5 cm) or insufficiently vascularized defects require intervention to repair. The overall goal of this project is to contribute towards the development of novel strategies to aid bone tissue regeneration by delivering mesenchymal stem cells expressing microRNAs that induce expression of the runt-related transcription factor 2 (RUNX2). It was determined that porous polycaprolactone (PCL) scaffolds fabricated to have a higher surface area to volume ratio (SVR) (> 80) compared to lower SVR (< 80) were hydrolyzed at a higher rate. Scaffolds fabricated with 80 vol. %/300–500 µm porogen were optimal for cell colonization as higher absorbance of metabolized MTT was detected compared to other scaffold types. From the subset of 5 miRNAs tested, miRNA-26a, miRNA-196 and miRNA-218 demonstrated higher upregulation of RUNX2 gene expression and calcium mineralization and thus, are promising candidates for bone tissue regeneration.

Vocational Rehabilitation Counselors' Experiences, Perceptions, And Readiness Related To Self-Employment Of People With Disabilities, Deborah Ashley

Theses and Dissertations

The purpose of this dissertation study was to explore the experiences, perceptions, and readiness (EPR) of vocational rehabilitation counselors (VRCs) supporting people with disabilities (PWD) in self-employment. While PWD are twice as likely to be self-employed than the general population, self-employment case closure rates within vocational rehabilitation remain historically low around 2%.

Descriptive, inferential, and correlational statistical analysis were used to investigate the EPR of 205 Certified Rehabilitation Counselors across the nation via an online survey, the Vocational Rehabilitation Counselor Self-Employment Process Survey (VRC-SEPS). The VRC-SEPS consists of demographic items, two Likert-type scales examining experiences and readiness, and a set …

Midguts, Microbes, And Mosquitoes: An Analysis Of The Microbiomes Of Aedes Aegypti And Aedes Albopictus, Flor Alicia Martinez

Theses and Dissertations

Experiment 1: Mosquito microbiomes are influenced by the environment and diets of mosquitoes. There is great variability within and among mosquito populations with few microbe inhabitants being well established among mosquitoes of similar species and environments. By understanding the potential variation in midgut microbiomes in lab and wild populations, we may assess the effect that microbiomes have on vector competency.

Experiment 2: Mosquito midgut microbes are essential for development and may influence the vector competency. Native and non-native strains of the midgut inhabitant, Cedecea, were introduced to laboratory colonies of Aedes aegypti and Aedes albopictus mosquitoes to help elucidate …

Cost Of Caring: The Effects Of Euthanasia On Animal Shelter Workers, Kim L. Nguyen-Finn

Theses and Dissertations

This mixed-methods study focuses on animal shelter workers, a population that has often been overlooked in research and clinical practice, and the emotional strains of the task of euthanasia. The effects of employment in a kill or no-kill shelter, participation in euthanasia, and number of years employed on mental health issues of substance abuse, anxiety, depression, secondary traumatic stress, and burnout were examined. A three-way MANOVA was run to test the hypothesis that there is a cell effect among the type of shelter employed in, participation in euthanasia, and years of experience on mental health, which was not supported by …

Impacts Of Habitat Attributes And Community Gardens On Urban Bird Communities, Samuel Glenn Ortiz

Theses and Dissertations

The Rio Grande Valley of Southern Texas is a major agricultural region yet has some of the highest hunger rates in the USA. Urbanization and agriculture affect biodiversity, which is well studied, but little is known about how agriculture affects biodiversity in urban areas. We investigated how different urban attributes, including those related to urban farming, impact bird communities in Brownsville and Harlingen, TX, and compared sites that have community gardens to those that do not. To study three key urban habitat characteristics, we identified sites that exhibited all possible combinations of these factors, quantified land cover classes related to …

Effects Of Invasive Nilgai Antelope (Boselaphus Tragocamelus ) Browsing On Black Mangrove (Avicennia Germinans) In South Texas: A Study On Microenvironmental, Physiological, Structural, And Reproductive Parameters, Tianna Picquet

Theses and Dissertations

Mangroves are important for coastal systems because they provide habitat for fish and bird species, mitigate erosion, and create an area for carbon sequestration. Along the Gulf of Mexico, at the southern tip of Texas, recent observations have shown that A. germinans stands (the dominant species in Texas) are being browsed on by invasive nilgai antelope (Boselaphus tragocamelus). The antelope were introduce to the south Texas region via King Ranch in the 1930’s and have since significantly increased in population and distribution. Previously thought to be grazers, B. tragocamelus were captured on camera utilizing A. germinans as a …

A Study Of Counselor Trainees' Self-Perceived Competency In Social Justice Advocacy, Mary Ann Rocha

Theses and Dissertations

The purpose of the study is to examine the social justice advocacy competencies of rehabilitation counselor trainees. The study aims to explore rehabilitation counselor trainees’ self-perceived social justice advocacy competencies. More specifically, counselor trainees’ demographic and training variables will be examined to understand the process of social justice advocacy competency. Also, the study will explore the correlation between social justice advocacy competency and ethical awareness. A convenience sample of counselor trainees who are in a master’s-level or doctoral level rehabilitation counseling program or related counseling program was utilized for this study. In total, 132 counselors in training completed the online …

Longitudinal And Temporal Comparison Of Beach Sand On The Rio Grande Delta System, Samantha B. Moore

Theses and Dissertations

The Rio Grande is the 5th longest river in North America and defines a significant extent of the United States-Mexico border. It extends for 2830 km from its headwaters in the Rocky Mountains of Colorado to the Gulf of Mexico. The Rio Grande is fed by streams from the Sangre de Cristo Mountains, the Rio Conchos, the Pecos River, runoff from the Sacramento Mountains area, Devils River, the Rio Salado, and the Rio San Juan. This study addresses how the composition of sand forming the Rio Grande river delta into the Gulf of Mexico at Boca Chica Beach is changed …

The Impact Of Foreign Aid On Extreme Poverty: A Case Study Of Liberia’S Development Complexities (1980-2018), Roosevelt Seedee

Electronic Theses and Dissertations

Many countries in West Africa, including Liberia, remain trapped in extreme poverty and dysfunctional social services amid continued increase in foreign aid. This study examines complexities influencing decisions of government donors in determining the kind of development assistance needed in Liberia and nation states in West Africa. This research explains the ways in which aid perpetuates poverty instead of alleviating it using interdisciplinary research approaches. Although aid is critical to Liberia’s development agenda, aid implementation faces numerous challenges because of extant poverty and rampant corruption.

Part of the problem in Liberia is not solely the failure of aid to meet …

The Study Of Alcoholic Liver Diseases, Seun Emmanuel Owoseni

Electronic Theses and Dissertations

Excessive alcohol consumption is the primary contributing factor in the development of alcoholic liver diseases (ALD). Nicotine contained in tobacco is a major addictive alkaloid, which enhances the effects of ALDs. The major enzyme involved in nicotine metabolism is cytochrome P450 2A5 (CYP2A5) which is produced in the liver. Alcohol can stimulate the CYP2A5 enzyme. We utilized cyp2a5-/- knockout mice in this research to examine the effects of CYP2A5.

The cyp2a5-/- mice and wild-type (WT) mice were fed liquid ethanol diet with or without nicotine to induce ALD. Nicotine enhancing effects on ALD were observed in WT mice but not …

The Role Of Cyp2a5 In Cadmium-Induced Liver Injury, Julia Salamat

Electronic Theses and Dissertations

Cadmium is present in food and groundwater. Tobacco smoking and occupational exposure are also major sources for cadmium. Cadmium is primarily accumulated in liver, a major organ metabolizing exogenous chemicals. Chemical metabolism may cause detoxification, but it can also cause bio-activation resulting in liver damage. Cytochrome P450s (CYP) are major liver metabolism enzymes, and cadmium chloride (CdCl2) can induce CYP2A5 in mice. We examined the effect of CYP2A5 on CdCl2-induced liver injury using CYP2A5-knockout (cyp2a5-/-) mice. The cyp2a5-/- mice and their control WT mice were injected CdCl2 intraperitoneally at 5 mg/kg body weight, respectively, to induce liver injury. …

Perceptions Of Confidentiality And Stigma Associated With Use Of Counseling Services, Jesi Hall

Electronic Theses and Dissertations

Counseling services are offered in most universities, but are often underutilized. Past researchers found that students listed time, cost, stigma, and confidentiality concerns as their top reasons for avoiding seeking help (e.g., Clement et al., 2015; Dearing, Maddux, and Tangney, 2005). The purpose of this study was to identify whether concerns about confidentiality affect stigma related to use of mental health services. Students answered questions about perceived stigma and the reasons they have avoided seeking counseling in the past. Those who had previously used services reported fewer confidentiality concerns. In a stepwise multiple regression, concerns about confidentiality were found to …

Imidacloprid Persistence, Mobility, And Effect On Ecosystem Function, Joanna Hardin

Electronic Theses and Dissertations

Imidacloprid is a neonicotinoid pesticide used to protect against biting and sucking insects. Land managers rely on its systemic properties, however long-term studies investigating imidacloprid effects on ecosystem function are limited. This study investigated imidacloprid applications to Tsuga caroliniana and Tsuga canadensis over time and compared concentrations to measures of ecosystem function including soil respiration, microbial function, and invertebrate density. Results indicate that imidacloprid is persistent (p0.5). Microbial function and invertebrate density were not significantly different between control and treatment locations nor did imidacloprid concentrations correlate with ecosystem functional indicator activity (p>0.05). It is evident that imidacloprid does not …

Outcomes Teacher Mentoring Has On Professional Learning And Delivery Of Instruction, Susana A. Zapata-Burguete

Theses and Dissertations

A qualitative study using grounded theory was conducted to discover how educational mentoring was transferred to subsequently transform instructional delivery in the second year of teaching for novice secondary school teachers. The study was conducted in a Deep South Texas public school district during the 2017–2018 academic year. After concluding a year of mentoring, interviews were conducted to reveal how the mentoring phenomena helped transform their present day delivery of instruction. Data was gathered through face-to-face interviews with seven participants. During this second year, the novice teachers primarily relied on both what was learned through their mentoring experiences and networking …

Radiative Heat Transfer Analysis Of Railroad Bearings For Wayside Thermal Detector Optimization, James Alexandro Aranda

Theses and Dissertations

Wayside hot-box detectors (HBDs) are devices that are currently used to evaluate the health of railcar components including bearings, axles, and brakes by monitoring their temperatures. While HBDs have been instrumental in reducing some train derailments in the past few decades, the number of non-verified bearing removals has increased significantly. In general, HBDs tend to underestimate bearing temperatures in both field service and in laboratory testing, which is not surprising considering the simple two-point calibration method that is used to calibrate these devices. Because of this, different calibrations were compared and analyzed including two-point, three-point, and multi-point calibrations. Analysis of …