Digital Commons Network^™

Genome-Wide Mega-Analysis Identifies 16 Loci And Highlights Diverse Biological Mechanisms In The Common Epilepsies., Bassel Abou-Khalil, Pauls Auce, Andreja Avbersek, Melanie Bahlo, David J. Balding, Thomas Bast, Larry Baum, Albert J. Becker, Felicitas Becker, Bianca Berghuis, Samuel F. Berkovic, Katja E. Boysen, Jonathan P. Bradfield, Lawrence C. Brody, Russell J. Buono, Ellen Campbell, Gregory D. Cascino, Claudia B. Catarino, Gianpiero L. Cavalleri, Stacey S. Cherny, Krishna Chinthapalli, Alison J. Coffey, Alastair Compston, Antonietta Coppola, Patrick Cossette, John J. Craig, Gerrit-Jan De Haan, Peter De Jonghe, Carolien G.F. De Kovel, Norman Delanty, Chantal Depondt, Orrin Devinsky, Dennis J. Dlugos, Colin P. Doherty, Christian E. Elger, Johan G. Eriksson, Thomas N. Ferraro, Martha Feuch, Ben Francis, Andre Franke, Jacqueline A. French, Saskia Freytag, Verena Gaus, Eric B. Geller, Christian Gieger, Tracy Glauser, Simon Glynn, David B. Goldstein, Hongsheng Gui, Youling Guo, Kevin F. Haas, Hakon Hakonarson, Kerstin Hallmann, Sheryl Haut, Erin L. Heinzen, Ingo Helbig, Christian Hengsbach, Helle Hjalgrim, Michele Iacomino, Andrés Ingason, Jennifer Jamnadas-Khoda, Michael R. Johnson, Reetta Kälviäinen, Anne-Mari Kantanen, Dalia Kasperavičiūte, Dorothee Kasteleijn-Nolst Trenite, Heidi E. Kirsch, Robert C. Knowlton, Bobby P.C. Koeleman, Roland Krause, Martin Krenn, Wolfram S. Kunz, Ruben Kuzniecky, Patrick Kwan, Dennis Lal, Yu-Lung Lau, Anna-Elina Lehesjoki, Holger Lerche, Costin Leu, Wolfgang Lieb, Dick Lindhout, Warren D. Lo, Iscia Lopes-Cendes, Daniel H. Lowenstein, Alberto Malovini, Anthony G. Marson, Thomas Mayer, Mark Mccormack, James L. Mills, Nasir Mirza, Martina Moerzinger, Rikke S. Møller, Anne M. Molloy, Hiltrud Muhle, Mark Newton, Ping-Wing Ng, Markus M. Nöthen, Peter Nürnberg, Terence J. O’Brien, Karen L. Oliver, Palotie Palotie, Faith Pangilinan, Sarah Peter, Slavé Petrovski, Annapurna Poduri, Michael Privitera, Rodney Radtke, Sarah Rau, Philipp S. Reif, Eva M. Reinthaler, Felix Rosenow, Josemir W. Sander, Thomas Sander, Theresa Scattergood, Steven C. Schachter, Christoph J. Schankin, Ingrid E. Scheffer, Bettina Schmitz, Susanne Schoch, Pak C. Sham, Jerry J. Shih, Graeme J. Sills, Sanjay M. Sisodiya, Lisa Slattery, Alexander Smith, David F. Smith, Michael C. Smith, Philip E. Smith, Anja C.M. Sonsma, Doug Speed, Michael R. Sperling, Bernhard J. Steinhoff, Ulrich Stephani, Remi Stevelink, Konstantin Strauch, Pasquale Striano, Hans Stroink, Rainer Surges, K. Meng Tan, Liu Lin Thio, G. Neil Thomas, Marian Todaro, Rossana Tozzi, Maria S. Vari, Ellen P.G. Vining, Frank Visscher, Sarah Von Spiczak, Nicole M. Walley, Yvonne G. Weber, Zhi Wei, Judith Weisenberg, Christopher D. Whelan, Peter Widdess-Walsh, Markus Wolff, Wolking Wolking, Wanling Yang, Federico Zara, Fritz Zimprich

Department of Neurology Faculty Papers

The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving 15,212 individuals with epilepsy and 29,677 controls, which reveals 16 genome-wide significant loci, of which 11 are novel. Using various prioritization criteria, we pinpoint the 21 most likely epilepsy genes at these loci, with the majority in genetic generalized epilepsies. These genes have diverse biological functions, including coding for ion-channel subunits, transcription factors and a vitamin-B6 metabolism enzyme. Converging evidence shows that the common variants associated with epilepsy play a role in epigenetic regulation of gene expression in the …

State V. Bybee Appellant's Brief Dckt. 46204

Not Reported

No abstract provided.

Analysis Of Spirit Of Charity Innovation District: Community Engagement, Development & Planning, Michelle M. Thompson Phd, Gisp, Adriana Bennett, Ashley Goodrich, Hoang Tao

Planning and Urban Studies Reports and Presentations

The purpose of this project is to give an overview of history, background, planning process of the Spirit of Charity Innovation District and the upcoming development of the former Charity Hospital Building.

Purpose of content analysis is to evaluate all forms of documents and articles available to see what major themes are discussed and carried out to get a sense of what qualities are the most important in the SCID.

Visualizing Stochastic Actor-Based Model Microsteps, Jimi Adams, David R. Schaefer

Faculty Publications

This visualization provides a dynamic representation of the microsteps involved in modeling network and behavior change with a stochastic actor-based model. This video illustrates how (1) observed time is broken up into a series of simulated microsteps and (2) these microsteps serve as the opportunity for actors to change their network ties or behavior. The example model comes from a widely used tutorial, and we provide code to allow for adapting the visualization to one’s own model.

Mental Health Problems Of The Youngest Generation Of American Veterans (Problemy Zdrowia Psychicznego Najmłodszego Pokolenia Weteranów Amerykańskich), Jaroslaw Richard Romaniuk

Faculty Scholarship

Wartime activities determine the threats to a soldier’s life and health. To prepare soldiers for a new forms of warfare, one should know the challenges the soldier faces in the midst of battle and after returning home. From 2001 to 2015, 1.2 million American soldiers returning from Iraq and Afghanistan used the health care services of the Department of Veterans’ Affairs. An analysis of the resulting medical interventions makes possible a long term evaluation of the effects of war, some of which appear only after the soldier returns to civilian life. This study analyzes the research on the mental health …

Eutrophi-What? An Inside Look At Algae Growth In Lakes And Rivers, Mia Difrancesco

D.U.Quark

No abstract provided.

Extraction Of Vital Signs Using Real Time Video Analysis For Neonatal Monitoring, Bhushan Lohani

Electrical Engineering Theses

Video data is now commonly used for analysis in surveillance, security, medical and many other fields. The development of low cost but high-quality portable cameras has contributed significantly to this trend. One such trend includes non-invasive vital statistics monitoring of infants in Neonatal Intensive Care Units (NICU). National Center for Health Statistics Publications has reported a high infant death rate (23,215 in 2014). This statistic has drawn the interest of health system professionals. Due to occurrence of conditions like bradycardia, apnea and hypoxia, these preterm infants are kept in an NICU for constant monitoring. One of the problems faced at …

December 10, 2018: Fall Saint Mary's Magazine Now Available, Provost’S Academic Growth & Innovation Fund, New Women’S Leadership Program, Saint Mary's College Of California

SMC Bulletin 2013-2020

No abstract provided.

Accuracy Of Wrist-Worn Activity Monitors During Common Daily Physical Activities And Types Of Structured Exercise: Evaluation Study., Ravi Kondama Reddy, Rubin Pooni, Dessi P. Zaharieva, Brian Senf, Joseph El Youssef, Eyal Dassau, Francis J. Doyle Iii, Mark A. Clements, Michael R. Rickels, Susana R. Patton, Jessica R. Castle, Michael C. Riddell, Peter G. Jacobs

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Wrist-worn activity monitors are often used to monitor heart rate (HR) and energy expenditure (EE) in a variety of settings including more recently in medical applications. The use of real-time physiological signals to inform medical systems including drug delivery systems and decision support systems will depend on the accuracy of the signals being measured, including accuracy of HR and EE. Prior studies assessed accuracy of wearables only during steady-state aerobic exercise.

OBJECTIVE: The objective of this study was to validate the accuracy of both HR and EE for 2 common wrist-worn devices during a variety of dynamic activities that …

Practice And Lived Experience Of Menstrual Exiles (Chhaupadi) Among Adolescent Girls In Far Western Nepal. December 2018, Prabisha Amatya, Saruna Ghimire, Karen E. Callahan, Binaya Kumar Baral, Krishna C. Poudel

School of Public Health Faculty Research

Background: Menstrual exile, also known as Chhaupadi, is a tradition of “untouchability” in far-western Nepal. Forbidden from touching other people and objects, women and girls are required to live away from the community, typically in a livestock shed, during menstruation. We assessed the lived experiences of Chhaupadi among Nepalese adolescent girls in the far-western Achham district of Nepal, observed the safety and sanitation of their living spaces during Chhaupadi, and assessed the perceptions of local adult stakeholders towards the practice of Chhaupadi. Methods: We collected data from 107 adolescent girls using a self-administered survey in two local schools in Achham. …

Ramblin’ Round Raton, University Of New Mexico Prevention Research Center

Community bio

Ramblin' Round Raton aims to promote healthy lifestyles through walking and hiking in Raton and on nearby public lands.

Edgewood, University Of New Mexico Prevention Research Center

Community bio

The Town of Edgewood continues its partnership with the National Parks Service, Rivers, Trails and Conservation Assistance Program (RTCA) in creating our Trails and Open Space Master Plan and Conceptual Drawings.

Week Of December 10, 2018, New York Medical College

InTouch

• HSL Hosts Special Exhibition and Presentation
• GSBMS Hosts Bake Sale to Benefit Victims of the California Wildfire
• NYMC Researcher Recalls Past Collaboration with Nobel Laureate George P. Smith, Ph.D.

A Multicase Study Exploring Women’S Narratives Of Infertility: Implications For Counselors, Staci L. Born, Christin L. Carotta, Kristine Ramsay-Seaner

The Qualitative Report

Infertility affects 6.7 million women in the United States (Chandra, Copen, & Stephen, 2013). Women’s experiences with infertility are not only influenced by biological health factors, but also by social, cultural, and personal variables. Given the prevalence and complexity of infertility, additional research is needed to further examine the nuances of women’s experiences. The purpose of this multicase study, as informed by four individual cases, was to explore how women construct their infertility narratives. Review of reflective journals found five common elements: (1) Emotional Rollercoaster, (2) Mind-Body (Dis)Connection, (3) Secret Identity, (4) Supportive vs. Constrained Communication Patterns, and (5) Fatalistic- …

Will Competition Law Solve The Vendor Lock-In Problem In The B2b Software Sector?, Piotr Semeniuk

internetowy Kwartalnik Antymonopolowy i Regulacyjny (internet Quarterly on Antitrust and Regulation)

Competition law is increasingly being used (so far, mainly in the US) in order to prevent the vendor lock-in problem in the B2B software sector. International academia also calls for increased activities of competition authorities in addressing vendor lock-in problems. Some business practices and contractual clauses applied by vendors in their Polish IT contracts could also be classified as an anticompetitive practice (e.g. exclusivities, tying, bundling, loyalty rebates, refusals to grant a license or to grant access to information on interoperability). Competition law in the world of IT contracts can supply buyers or competitors with arguments to challenge some of …

Merger Control In The Big Data Era – On The New Jurisdictional Threshold Based On The Transaction Value Criterion In The Context Of The European Commission’S Decision-Making Practice And The Amendments To Austrian And German Antitrust Laws, Laura Skopowska

internetowy Kwartalnik Antymonopolowy i Regulacyjny (internet Quarterly on Antitrust and Regulation)

During a recent consultation of the European Commission on the assessment of the procedural and jurisdictional aspects of EU merger control, the Commission expressed significant doubts regarding its notification system based solely on a turnover criterion, which can create significant enforcement gaps while assessing acquisitions taking place in the digital and pharmaceutical markets. In the Big Data era, when databases are of increasing market importance, current jurisdictional thresholds may not be a sufficient tool to detect anticompetitive acquisitions on the digital market. This scientific article assesses whether the introduction of new criteria is justified. The article also includes an analysis …

Tertiary Ammonia Treatment Of Lagoon Effluent Using Microvi MneTm Technology, Bryan Burbank, Sydney Burtenshaw, Nathan Guymon, Mike Langston, Luke Lemmon

Biological Engineering

Nutrient pollution is a growing problem threatening many waterways. High levels of nitrogen and phosphorus in water can cause algae to grow rapidly. This growth decreases water quality, kills aquatic life, and elevates toxin levels creating health hazards for people. Due to increases in nitrogen and phosphorus pollution, the Logan City regional wastewater treatment plant is currently updating from a lagoon system to a mechanical plant to meet future discharge limits imposed by federal, state, and local governments. The intent of our design is to add a tertiary nitrification system using Microvi MicroNiche Engineering^TM (MNE^TM) technology.

Tertiary Wastewater Treatment Through Mbbr Technology, Ethan Ackerman, Grant Harris, Gregory Jensen, Christopher Ruben, Stephen Sadler

Biological Engineering

Wastewater treatment is an essential component to public health as it removes harmful compounds and allows for water reuse and recycle. Biological nutrient removal has entered into the public spotlight as effluent flows with high nitrogen concentrations have detrimental effects on water discharge bodies. Traditional suspended growth biological treatment methods are expensive and produce excess biomass that can reduce the efficiency of nutrient removal if not maintained. Research on the benefits of attached growth processes, namely moving bed biofilm reactor (MBBR) technology, presents an exciting innovation in wastewater treatment that can increase nutrient removal efficiency and reduce overall cost.

As …

Testing The Structural Invariance Of Affective Commitment On Unethical Pro-Organizational Behavior Across Clan And Hierarchy Organizational Culture Types, Julia A. Fulmore

Human Resource Development Theses and Dissertations

Unethical pro-organizational behavior (UPB) is concerned with employees’ engagement in unethical conduct for the benefit of the organization that is immoral and/or illegal. Research findings on motivators of UPB show some contradictory findings that need to be resolved. Considering the empirical findings that clan culture discourages unethical behavior while hierarchy culture encourages unethical behavior along with the contradicting empirical findings between affective commitment and UPB based on samples with different cultures, this study sought to empirically assess the contradictory findings in the literature by testing the structural invariance of affective organizational commitment on UPB based on the two organizational of …

#Work2bewell Powered By Providence Health & Services, Robin Henderson, Mary Renouf-Hanson

Books, Presentations, Posters, Etc.

Improving mental health and emotional well-being is the focus of many community health assessments and prevention efforts. This session will focus on innovative ideas that engage youth and their families where they are—in schools, communities and while seeking healthcare. Learn from healthcare leaders at Bellin Health, Cincinnati Children’s, Providence St Joseph Health and East London NHS Foundation Trust and their community partners as they share their successful efforts to change the conversation with today’s youth.

Lanthorn, Vol. 53, No. 17, December 10, 2018, Grand Valley State University

Volume 53, July 9, 2018 - June 10, 2019

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Ohio University Faculty Senate Minutes December 10, 2018, Ohio University Faculty Senate

Faculty Senate Minutes

No abstract provided.

The Effects Of Exercise On The Cognitive Function Of Patients With Alzheimer’S Disease, Amanda Savitski

Honors Theses

Alzheimer’s disease (AD) is America’s most common neurodegenerative disease affecting over 5.4 million Americans (Fernández et al., 2017). A literature review was completed to assess the possible relation between physical activity and the progression of AD. Articles were collected from various peer-reviewed, published journals using the available databases of Western Michigan University library which included PubMed, ClinicalTrials.gov, and the National Institute of Health (NIH). Keywords used for the database searches included “Alzheimer”, “Alzheimer’s Disease”, “neurodegeneration”, “aging brain”, “exercise”, and “physical activity”. Based upon the literature reviewed, aerobic exercise appears to slow the progression of AD and possibly reverses it slightly …

Conscious Consumerism: A Design Process For Stylish Sustainable Apparel, Luz Becerra

Honors Theses

The main objective of this paper is to explore current consumer behavior and perspective on sustainable apparel as well as future trends in the market place such as willingness to buy. I investigated the market for organic apparel brands, and identified potential areas of growth. My findings concluded that young consumers lack interest in sustainable apparel because they are not sufficiently educated in the topic and are not willing to sacrifice their style identity, consequently purchasing trendy fast-fashion items. The fashion industry is famously claimed to be the second most polluting industry in the world, so I designed a line …

Research-Based Music Composition For Anxiety Reduction, Carly Crusius

Honors Theses

The following undergraduate honors thesis utilizes the Therapeutic Function of Music (TFM) Plan worksheet conceived by Dr. Deanna Hanson-Abromeit as a template to guide research and analysis for how the musical elements should be structured to support the goal of anxiety reduction for college-aged students. Anxiety is a mental health concern that is prevalent among college students due to the variety of social, environmental, and academic stressors that affect their day-to-day lives. The TFM was established to provide transparency and a common language within the field of music therapy and beyond when discussion the elements of music. Research was conducted …

Census Study Of Ducks, Swans And Geese From High-Altitude Wetlands Of Pakistan, Fakhra Nazir, Inayatullah Malik, Safdar Ali Shah

Journal of Bioresource Management

The family Anatidae consists of aquatic birds such as ducks, geese and swans of varied sizes that belong to the order Anseriformes (Carboneras, 1992). The Anatidae comprise of approximately 148 species (Johnsgard, 2010). This family is commonly found across the globe except for in Antarctica. Data on ecology and population of these water birds was taken from protected areas of Pir Lasura National Park (June-July 2009), Banjosa Game Reserve (May-June 2009), Dhirkot National Park (February 2008), Pir Chanasi National park (April-May 2010) and Tolipir National Park (April-May 2008). Only four species from the family Anatidae were found in the study …

The Value Of 'Having A Go': Trialling A Project-Based Learning Activity To Inform Curriculum Design, Alison Stokes, Nichola Harmer

School of Geography, Earth and Environmental Sciences

No abstract provided.

Development And Implementation Of A Social Needs Screener In Primary Care Practice, Beth Careyva M.D., Cathy A. Coyne Phd, Mph, Roya Hamadani Mph, Deborah Bren Do

Department of Family Medicine

No abstract provided.

Medical School Watercooler Newsletter - December 9, 2018, Lindsey Lyle

Watercooler Newsletter

This is the December 9, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Faculty Honored at Inventor Recognition Luncheon
• Register Now: Pediatrics Symposium Set for Jan. 18
• 12th Annual COM Research Forum Winners Announced
• Mark Your Calendar: Forum on Community-Engaged Scholarship Set for Jan. 11
• Med School Café: Expert Advice for the Community

Practice Facilitator Role In An Operational Project To Improve Access In A Large Multi-Specialty Physician Group, Jean D'Aversa Bsn, Rn, Yuriko A. De La Cruz Mph, Kristie M. Knouse Bs

Department of Family Medicine

No abstract provided.