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Trends And Factors Associated With Breastfeeding In Thailand : A Secondary Analysis Of The Multiple Indicator Cluster Survey 2005-2016, Yuanpei Chen
Chulalongkorn University Theses and Dissertations (Chula ETD)
This cross-sectional study was based on secondary data of Thailand Multiple Indicator Cluster Survey (MICS round 3, 4 and 5) between 2005 and 2016 and aimed to identify trends and factors associated with breastfeeding in Thailand. Subjects were selected from the three MICS surveys and then pooled together to form final weighted samples of 9757 children under 2 years for studying early initiation of breastfeeding and 2568 children under 6 months for exclusive breastfeeding. Univariate and multivariate logistic regression analyses were applied to identify trends and factors. Results indicated that the overall breastfeeding rates were low in spite of an …
Effectiveness Of Thai Hermit Exercise (Ruesi Datton) On Mild Cognitive Impairment's Patients, Chomlak Kongart
Effectiveness Of Thai Hermit Exercise (Ruesi Datton) On Mild Cognitive Impairment's Patients, Chomlak Kongart
Chulalongkorn University Theses and Dissertations (Chula ETD)
Mild Cognitive Impairment (MCI) is a recurrent brain disorder in memory. It is caused by the degeneration of the brain cells that is different from an individual's age and develop to dementia. One way to help restore memory is to exercise. Thai hermit exercise is a wisdom in Thai exercise, which improve memory decline for the condition. The study design is randomized control trial. This study aimed to investigate the effectiveness of Thai hermit exercise among patients with MCI. 84 participants were recruited and randomized into intervention (n=42) control(n=42). The intervention group practiced Thai hermit exercise for 10 weeks. Psychological …
Health Policies And Programs Facilitating Access To High-Cost Anticancer Drugs, Chanthawat Patikorn
Health Policies And Programs Facilitating Access To High-Cost Anticancer Drugs, Chanthawat Patikorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Access to anticancer drugs is limited mainly due to their high cost. To support policymakers in Thailand to develop policies and programs to facilitate better access to high-cost anticancer drugs, global and local evidence are needed. A systematic review of literature was conducted using PubMed, Embase and Web of Science between October 8-11, 2018 to identify peer-reviewed articles published in English from 2000 to 2018. Studies were included if they described health policies or programs facilitating access to high-cost anticancer drugs. Using thematic synthesis, policies and programs were summarized by themes and by income classification of countries. In addition, a …
Pharmacognostic Specification And Brazilin Content In Caesalpinia Sappan Heartwoods, Macroscopic, Microscopic And Molecular Identification Of Selected Caesalpinia Species In Thailand, Suwipa Intakhiao
Chulalongkorn University Theses and Dissertations (Chula ETD)
The genus Caesalpinia L. belongs to Caesalpiniaceae family. This genus was spread throughout Asia and South East Asia. In Thailand, 18 species of Caesalpinia L. genus were reported which were spread in every parts. Due to the similar morphology especially the leaf part and closely vernacular name of eight Caesalpinia species, the identification of these species is complicated. Caesalpinia sappan L. is the well-known species which has many important drug properties. It was used as food, beverage, and cosmetic industries especially the heartwood part that contained brazilin, one of the flavonoid group. This study aimed to establish the pharmacognostic specification, …
Needs Analysis And Development Of Professional Development Program For Thai Community Pharmacists, Surangkana Puengrung
Needs Analysis And Development Of Professional Development Program For Thai Community Pharmacists, Surangkana Puengrung
Chulalongkorn University Theses and Dissertations (Chula ETD)
Background: Primary care services, as recommended by the National Health Security Office (NHSO), are crucial for Thai community pharmacists. Training needs for the services and a professional development or training program however remained unexplored. Objectives: To analyze community pharmacists' training needs and develop professional development programs to meet their needs. Methods: A mixed-methods study with two phases was conducted during 2018-2019. Phase 1 was involved in the needs assessment using semi-structured interview with 10 key informants who were community pharmacists and stakeholders based on three levels (i.e. tasks, person, and organization) and needs confirmation with a self-administered questionnaire surveyed in …
Indonesia's Role In Humanitarian Crisis In Rakhine State Of Myanmar (2012- 2017), Muhammad Indrawan Jatmika
Indonesia's Role In Humanitarian Crisis In Rakhine State Of Myanmar (2012- 2017), Muhammad Indrawan Jatmika
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis begins with the question of why does Indonesia consider the humanitarian crisis that occurred in Rakhine State of Myanmar as a very important issue and needs to be taken seriously by conducting soft power diplomacy and humanitarian assistance to address the crisis? Indonesia has the rational choice of conducting soft diplomacy in the form of bilateral and multilateral responses, as well as providing humanitarian assistance in the crisis that occurred in Rakhine state. Theoretical discussion of this paper is carried out on the theory by William D Coplin on various factors that influence the process of foreign policy …
Education And Identity Of Myanmar Migrant Children In Samut Sakhon Province, Shan Li
Education And Identity Of Myanmar Migrant Children In Samut Sakhon Province, Shan Li
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this research is to explore the educational status and identity of Myanmar migrant children in Samut Sakhon Province and to analyze the different roles and influences of formal and informal educational models on these children's identity. For Myanmar migrant children who live in Thailand, due to their living environment are different from their parents, they seem to face identity challenges. The analysis of the identifying characteristics of Myanmar migrant children is not only contributing to the understanding of the current situation of Myanmar migrant children in Thailand but also can broaden the understanding about the factors that …
From “Burmese Brides” To Burmese Wives : Analyzing Transnational Marriages Of Women From Myanmar To Chinese Men Along The Myanmar-Yunnan Frontier, Xuanyi Luo
Chulalongkorn University Theses and Dissertations (Chula ETD)
Since around 2000, there has a growth of Myanmar women who have married men in Yunnan, China. Media reports from China, Myanmar and the West typically call these women "Burmese brides" and link them to human trafficking, fake marriages, HIV-AIDS, among other issues. This gives the public a negative impression of these women, and views them as mostly vulnerable victims caught in a faceless transnational marriage process. This thesis seeks to correct this limited view and provide a fuller picture of these women and to stress the role of their choice or "agency" in forming their transnational marriages beyond the …
New Chinese Migrants Enterpruner In Thailand: The Case Study Of Jong-Thai Jianming Eiw Ea (Group) Co., Ltd., Yuge Liu
Chulalongkorn University Theses and Dissertations (Chula ETD)
The study of the overseas Chinese in Thailand has been broadly conducted by many scholars. However, such have mainly focused on the overseas Chinese who came from the southeastern part of China, as they were the major part of the Chinese migrants to the Southeast Asian region from the ancient to modern times, and today they still play a great role in this region. Major themes in these studies include the identification of the Chinese migrants (who they were or where they had come from), various Chinese associations, big families of Chinese entrepreneurs and etc. On the contrary, the study …
Roles Of Actors In The Development Of Organic Farming In Baan Non-Yang, Amphoe Kud-Chum, Yasothon Province, Yan-Ting Huang
Roles Of Actors In The Development Of Organic Farming In Baan Non-Yang, Amphoe Kud-Chum, Yasothon Province, Yan-Ting Huang
Chulalongkorn University Theses and Dissertations (Chula ETD)
Organic agriculture in Thailand has been shaped by the agency factors with contestation on development in structural contexts since the 1970s. It emerged and developed as a part of alternative agriculture movement, and transformed in dynamic contexts with involvement of various actors. Organic farming in Non-Yang community can be perceived as the microcosm of the development. POs, NGOs, GOs and private sectors are involved into the community as actors of organic farming network. With negotiation and cooperation in the network, the movement has persisted and become viable until today. The thesis was conducted with a stakeholder analysis on the case …
The Effect Of Tranforming From A Colony To A Nation-State On Chinese Diaspora Identity In Southeast Asia : Case Study Of The Chinese Emigration From The Malay Peninsula, 1945-1979, Huiwen Xue
Chulalongkorn University Theses and Dissertations (Chula ETD)
During the period between 1945 and 1979, the Malay Peninsula was under a chaotic and turbulent social situation. Decolonization, ideological confrontation, and ethnic conflict all happened in this period. This research adopts the documentary research method to analyze how the turbulent social situation affected Chinese society in Malaya/Malaysia and how the problems that the ethnic Chinese of the Malay Peninsula faced affected the Chinese emigration from the Malay Peninsula. During the anti-colonial period, part of the ethnic Chinese of Malaya identified with China and sympathized with the Chinese Communist Party. Hence, China was the most important destination for them. Afterward, …
The Adaption Of Phở In Vietnam After 1986, Kunyarat Saengul
The Adaption Of Phở In Vietnam After 1986, Kunyarat Saengul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Phở is known as a national dish of Vietnam. It is originated in the north of Vietnam as a labour food. With its popularity, phở spread all over the country adapted to ingredients and way of cooking in each place. After the socio-economic reform (Đổi Mới) in 1986, Vietnam's economy was shifted from centrally planned to market-based. As a result, there are changes in the growth of 3 groups of people; the middle-income class, the overseas Vietnamese, and the rural-urban migrants and low-income class in urban Vietnam. Meanwhile, the reform encouraged the growth of tourism in which pho has been …
Tea Culture Tourism In Southeast Asia : A Comparative Study Of Mae Salong In Thailand And Thai Nguyen In Vietnam, Yanling Guo
Tea Culture Tourism In Southeast Asia : A Comparative Study Of Mae Salong In Thailand And Thai Nguyen In Vietnam, Yanling Guo
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study attempts to explore the development of tea planting and producing, and tea culture tourism in Mae Salong in Thailand and Thai Nguyen in Vietnam. The findings reveal that tea planting in Mae Salong is derived from KMT villagers in northern Thailand who initially planted tea for livelihood, later developed as a cash crop for substituting opium and reducing soil erosion under the cooperation between the Royal Project and Taiwanese organizations. Nowadays, tea in Mae Salong is selected as "OTOP" and marketed as tourism resources to attract tourists. The tea culture tours in Mae Salong are usually organized with …
The Effect Of Recovery Combination On Muscle Oxygenation, Blood Lactate Concentration, And Subsequent Performance During 200-M Repeated Swimming, Ade Bagus Pratama
The Effect Of Recovery Combination On Muscle Oxygenation, Blood Lactate Concentration, And Subsequent Performance During 200-M Repeated Swimming, Ade Bagus Pratama
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to compare the effectiveness of three recovery protocols on muscle oxygenation, blood lactate, and subsequent performance during a 200-m repeated swimming. Twelve swimmers (6 females and 6 males) from Chulalongkorn University swimming club completed three sessions of two consecutive 200-m front crawl trials separated by one of three recovery protocols: a 15-min of active recovery (AR), a 15-min of passive recovery (PR), and a recovery combination of 5-min of active and 10-min of passive recovery (CR) by using a counterbalance design. Skeletal muscle oxygenation, blood lactate concentration (BL), arterial oxygen saturation (SaO2), and heart rate (HR) were …
The Role Of Consumer Determinants In The Relationship Between Brand Equity And Behavioral Intentions, Hanh Tran Thi My
The Role Of Consumer Determinants In The Relationship Between Brand Equity And Behavioral Intentions, Hanh Tran Thi My
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this study is to examine the relationship between brand equity and behavioral intentions (i.e., repurchase, recommend) as well as the moderating role of consumer determinants (i.e., trust, satisfaction, perceived electronic word-of-mouth) in this relationship within hedonic and utilitarian high-involvement product settings. The study employs a quantitative approach in which the cross-sectional survey was made to collect the data in Bangkok, Thailand. A total of 423 target samples aged from 18 to 25, studying and/or working in inner areas, were collected. The findings illustrate that brand equity is positively related to behavioral intentions in both contexts. Additionally, trust, …
Personal Branding Strategies Of Influential Youtubers And Perceptions Of Thai Millennials Toward Them, Chanamon Phansab
Personal Branding Strategies Of Influential Youtubers And Perceptions Of Thai Millennials Toward Them, Chanamon Phansab
Chulalongkorn University Theses and Dissertations (Chula ETD)
Personal branding—how individuals establish and communicate their unique traits and skills to facilitate their life goals—has become a topic of interest for many scholars and practitioners alike. One of the most widely used channels through which personal branding is executed is YouTube. There are several YouTubers, as we speak, who strive to promote their channel—their personal brand—by establishing their online identity and communicating such identity to their target audience. The studies have shown that the main target audience on YouTube, whose rising influence boosts the popularity of online video content viewing, is the millennials, especially Thai millennials as Thailand is …
The Relationship Between Facebook Users' Motivation On Environmental Issues, Environmental Awareness And Behavioral Tendency In Vietnam, Linh Nguyen Ba Tue
The Relationship Between Facebook Users' Motivation On Environmental Issues, Environmental Awareness And Behavioral Tendency In Vietnam, Linh Nguyen Ba Tue
Chulalongkorn University Theses and Dissertations (Chula ETD)
The objectives of this research were to study the Facebook users' motivation on environmental issues, their environmental awareness and behavioral tendency in Vietnam and to explore the relationship among these three variables. Three social media influencers who had more than 10,000 followers on their Facebook profiles, demonstrated open, explicit environmentally-friendly lifestyle and achieved certain media recognition were invited to join in-depth interviews. Four hundred and fifty eight Vietnamese male and female respondents, aged between 18 and 45 years old and currently residing in Vietnam, were asked to complete an online and offline questionnaire survey. The results depicted that the respondents …
Effects Of Autonomy-Supportive English Language Instruction On Students' Motivation In English Language Classrooms, Mintra Phithakmethakun
Effects Of Autonomy-Supportive English Language Instruction On Students' Motivation In English Language Classrooms, Mintra Phithakmethakun
Chulalongkorn University Theses and Dissertations (Chula ETD)
The present study aimed at exploring the effects of Autonomy-Supportive English Language Instruction on students' motivation in English language classrooms, and aimed at investigating students' opinions toward Autonomy-Supportive English Language Instruction. The participants were 25 eleventh grade students who were studying in a public school in the second semester of the academic year 2018, which were selected by purposive sampling. The research instruments were students' self-report motivation in English language classrooms questionnaire, and students' opinions toward autonomy-supportive English language instruction interview questions. The data were analyzed using descriptive statistics, paired-sample t-test and content analysis. The results revealed that students' motivation …
The Effects Of Communicative Framework Instruction Using Computer-Assisted Pronunciation Training (Capt) On English Pronunciation Ability Of Chinese Undergraduate Students, Ching-Yueh Chang
Chulalongkorn University Theses and Dissertations (Chula ETD)
The study aimed 1) to examine the effects of the communicative framework instruction using CAPT on the English pronunciation ability of Chinese undergraduate students; 2) to investigate the opinions of students towards the communicative framework instruction using CAPT. The participants consisted of 17 Chinese undergraduate students in at Siam University at during the first semester of the 2018 academic year in 2018. The instruments used to collect data were a pronunciation pre-test and a post-test, a student opinion questionnaire, and semi-structured interview questions. The analyzed statistics computed from the data included the mean scores, standard deviation, and Wilcoxon signed ranks …
Immersive Learning To Enhance International Exposure In Thai Technopreneurs, Siripen Buranapatimakorn
Immersive Learning To Enhance International Exposure In Thai Technopreneurs, Siripen Buranapatimakorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
The ability of Thai technopreneurs to build the right technology product in the right market and to acquire funding is closely tied to their international exposure. However, many lack the financial resources required to obtain international exposure, putting them at a disadvantage in confidence and communication skill at international level. This research explores an affordable and effective solution for providing simulated international exposure to technopreneurs via immersive learning technology. Virtual reality (VR) is an immersive technology that provides a computer-generated three-dimensional environment, in which people can physically and mentally interact. This research investigates the feasibility of employing VR technology as …
Impacts Of Communication Technology And Social Media On Intergenerational Relationships In Bangkok, Marie-Helene Thomas
Impacts Of Communication Technology And Social Media On Intergenerational Relationships In Bangkok, Marie-Helene Thomas
Chulalongkorn University Theses and Dissertations (Chula ETD)
The objective of this research is to explore how communication technology and social media affects the intergenerational relationships between older persons and their adult children in Bangkok. Using Bengston and Schrader's (Bengtson and McChesney 1998) measurement framework for intergenerational relationships, this study examines how communication technology, namely the smart phone and its accompanying applications, Line and Facebook, has impacted the relationship between thirty older persons and their adult children. Purposive sampling was used to select participants from three elderly associations located in different neighbourhoods around Bangkok, data was collected using semi-structured interviews and data was analysed via thematic analysis. The …
The Creation Of A "Lanna Sense Of Place" Through Fine Arts In Northern Thailand : A Case Study Of Hotel Lobby Decorations In Chiang Mai And Chiang Rai, Muhammad Faizal Abdul Rani
The Creation Of A "Lanna Sense Of Place" Through Fine Arts In Northern Thailand : A Case Study Of Hotel Lobby Decorations In Chiang Mai And Chiang Rai, Muhammad Faizal Abdul Rani
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation will observe and evaluate how the Northern region of Thailand had applied various cultural elements and beliefs in creating a "Sense of Lanna" to attract visitors. How these cultural elements had been applied by the various parties will demonstrate the manner of their commercialization - whether in a positive or negative way. The scope of this research is focused on seven 5-star hotels in Chiang Mai and Chiang Rai. This area was chosen because Chiang Mai is the most award-winning province in Thailand when it comes to tourism especially. This is in addition to the area having many …
Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum
Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum
Chulalongkorn University Theses and Dissertations (Chula ETD)
The main overall goal of this study is to investigate the application of modified chitosan as a potential vector for apoptotic gene delivery to gonadotropin-releasing hormone receptor (GnRHR)-expressing cells (i.e. testicular cells and mammary cancer cells). This study reported Gonadotropin Releasing Hormone-modified Chitosan (GnRH-CS) nanoparticle as a promising vector for targeted gene delivery, and a GnRH peptide was used for active targeting of a transgene in GnRHR expressing cells. The physiological characterizations of the prepared nanoparticle were investigated by proton nuclear magnetic resonance spectroscopy (1H NMR), Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and Nanosizer. The prepared GnRH-CS was …
Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti
Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti
Chulalongkorn University Theses and Dissertations (Chula ETD)
Diagnosis of Canine Monocytic Ehrlichiosis is in light of anamesis, visualized cytoplasmic morulae, clinical signs and laboratory test result of platelet counts. The PCR technique is always a definitive confirmatory test of Ehrlichia canis infection. However, the drawback of PCRs test is crucially needed of laboratory equipments. This drawback is somehow enabled newly DNA based technology to be developed in order to eliminate laborious thermocycler and gel electrophoresis. The LAMP-LFD is on focus by using a single temperature to amplify DNA and no gel electrophoresis involved to detect DNA product. LAMP-LFD is included in DNAsensor test kit that recently developed …
The Role Of Ancestral Halls And Ancestral Worship In Chinese Clan Associations In Thailand As Forms Of Cultural Integration In The Age Of Globalization, Ying Zhang
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation focuses on studying the relationship between the ancestral hall and ancestral worship of Thai-Chinese clan associations in the context of contemporary Thai society, Thai local culture and the era of globalization. The research data mainly derives from the journals of the Thai-Chinese communities, news reports, on-site investigations and interviews. This study indicates that the Thai-Chinese had been living in Thai society and they had established Chinese traditional cultural practices in Thailand and enriched the culture of Thailand. With the development of contemporary Thai society, Thai-Chinese community associations have been transformed into non-governmental organizations and have become part of …
The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya
The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya
Chulalongkorn University Theses and Dissertations (Chula ETD)
Monosodium glutamate (MSG) is composed of sodium salt and amino acids that is commonly used to enhance food taste. Although it is safe at consumption level, the adverse effect of MSG had been reported. The present research was intended to evaluate the effect of MSG on the brain, liver, kidney, testes, and ovaries of zebrafish (Danio rerio) which were exposed from embryo stage to adult stage, along with the analyzing of the fertilization rate and hatching rate of zebrafish embryos. From the observation of histopathological changing of different organs of zebrafish after exposed to 10, 100, and 1000 ppm MSG …
Synbiotic Effects Of Jerusalem Artichoke (Helianthus Tuberosus) And Lactobacillus Rhamnosus-Supplemented Diet On Growth Performance, Immunological Parameters And Protection Against Aeromonas Veronii Challenge In Juvenile Red Tilapias (Oreochromis Spp.), Mariya Sewaka
Chulalongkorn University Theses and Dissertations (Chula ETD)
Synbiotics, a synergistic combination of probiotics and prebiotics, are now highlighted as one of the most practical nutritional supplements in red tilapia farms. The aim of the present study was to assess the effect of the dietary inclusion of Jerusalem artichoke, Lactobacillus rhamnosus, or their combination, on serum biochemical, growth performance, intestinal morphology, immune parameters, intestinal bacterial count and protection against Aeromonas veronii in juvenile red tilapia (Oreochromis spp.). One hundred and eighty male red tilapias (average body weight of 14.05±0.42 g) were distributed into six 1000-liter tanks containing water under continuous aeration and an average temperature of 25–28°C. Tilapias …
The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad
The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad
Chulalongkorn University Theses and Dissertations (Chula ETD)
Porcine epidemic diarrhea is caused by porcine epidemic diarrhea virus (PEDV), which causes swine watery diarrhea and higher mortality rates in piglets less than one week of age. Outbreaks of PED affect to economic loss, especially in a swine industrial country. Many strategies were used for preventing the outbreak and infection of PEDV, especially maternal antibody stimulation in pigs and then transfer to piglet through colostrum or milk. Thus, the investigation of antibody level for the situation on the farm is required. The method which convenient and rapid than viral neutralization (VN) test is an enzyme-linked immunosorbent assay (ELISA). The …
Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij
Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij
Chulalongkorn University Theses and Dissertations (Chula ETD)
Brugia pahangi is a major causative agent of animal lymphatic filariasis, one of the neclected tropical disease. Recent studies have also indicated that B. pahangi can cause clinical infection in human, with clinical appearances which are consistent with human lymphatic filariasis. Nowadays, the recognition of Wolbachia as new alternative drug choice for treatment and control of lymphatic filariasis is the most important in anti-filarial chemotherapy. Since, Wolbachia play important roles, including the development, viability, fertility and fecundity of filarial parasites. Depletion of Wolbachia results in sterilization, stunting and death of filarial worms. In this study, we investigated the effects of …
Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen
Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Retinal (retinaldehyde) is one of natural vitamin A metabolites. It is widely used in clinical dermatology such as acne, acne scar, photoaging, wrinkles, psoriasis, skin neoplasia and seborrheic dermatitis. Retinal is a pivotal key to regulate keratinocyte proliferation and differentiation in the epidermis resulting in epidermal thickening and inhibit collagen destruction in the dermis. However, topical application of retinal is still irritative to the skin and chemically and photochemically unstable. Topically applied retinal can induce a retinoid dermatitis. This inflammation is induced by an overload of non-physiological amounts of exogenous retinoic acid in the skin. The adverse effects and physicochemical …