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The Effects Of Communicative Framework Instruction Using Computer-Assisted Pronunciation Training (Capt) On English Pronunciation Ability Of Chinese Undergraduate Students, Ching-Yueh Chang
Chulalongkorn University Theses and Dissertations (Chula ETD)
The study aimed 1) to examine the effects of the communicative framework instruction using CAPT on the English pronunciation ability of Chinese undergraduate students; 2) to investigate the opinions of students towards the communicative framework instruction using CAPT. The participants consisted of 17 Chinese undergraduate students in at Siam University at during the first semester of the 2018 academic year in 2018. The instruments used to collect data were a pronunciation pre-test and a post-test, a student opinion questionnaire, and semi-structured interview questions. The analyzed statistics computed from the data included the mean scores, standard deviation, and Wilcoxon signed ranks …
Immersive Learning To Enhance International Exposure In Thai Technopreneurs, Siripen Buranapatimakorn
Immersive Learning To Enhance International Exposure In Thai Technopreneurs, Siripen Buranapatimakorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
The ability of Thai technopreneurs to build the right technology product in the right market and to acquire funding is closely tied to their international exposure. However, many lack the financial resources required to obtain international exposure, putting them at a disadvantage in confidence and communication skill at international level. This research explores an affordable and effective solution for providing simulated international exposure to technopreneurs via immersive learning technology. Virtual reality (VR) is an immersive technology that provides a computer-generated three-dimensional environment, in which people can physically and mentally interact. This research investigates the feasibility of employing VR technology as …
Impacts Of Communication Technology And Social Media On Intergenerational Relationships In Bangkok, Marie-Helene Thomas
Impacts Of Communication Technology And Social Media On Intergenerational Relationships In Bangkok, Marie-Helene Thomas
Chulalongkorn University Theses and Dissertations (Chula ETD)
The objective of this research is to explore how communication technology and social media affects the intergenerational relationships between older persons and their adult children in Bangkok. Using Bengston and Schrader's (Bengtson and McChesney 1998) measurement framework for intergenerational relationships, this study examines how communication technology, namely the smart phone and its accompanying applications, Line and Facebook, has impacted the relationship between thirty older persons and their adult children. Purposive sampling was used to select participants from three elderly associations located in different neighbourhoods around Bangkok, data was collected using semi-structured interviews and data was analysed via thematic analysis. The …
The Creation Of A "Lanna Sense Of Place" Through Fine Arts In Northern Thailand : A Case Study Of Hotel Lobby Decorations In Chiang Mai And Chiang Rai, Muhammad Faizal Abdul Rani
The Creation Of A "Lanna Sense Of Place" Through Fine Arts In Northern Thailand : A Case Study Of Hotel Lobby Decorations In Chiang Mai And Chiang Rai, Muhammad Faizal Abdul Rani
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation will observe and evaluate how the Northern region of Thailand had applied various cultural elements and beliefs in creating a "Sense of Lanna" to attract visitors. How these cultural elements had been applied by the various parties will demonstrate the manner of their commercialization - whether in a positive or negative way. The scope of this research is focused on seven 5-star hotels in Chiang Mai and Chiang Rai. This area was chosen because Chiang Mai is the most award-winning province in Thailand when it comes to tourism especially. This is in addition to the area having many …
Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum
Innovation Of Gonadotropin Releasing Hormone (Gnrh)-Modified Nanocarrier Delivered To Induce Testicular And Mammary Cell Apoptosis, Chatwalee Boonthum
Chulalongkorn University Theses and Dissertations (Chula ETD)
The main overall goal of this study is to investigate the application of modified chitosan as a potential vector for apoptotic gene delivery to gonadotropin-releasing hormone receptor (GnRHR)-expressing cells (i.e. testicular cells and mammary cancer cells). This study reported Gonadotropin Releasing Hormone-modified Chitosan (GnRH-CS) nanoparticle as a promising vector for targeted gene delivery, and a GnRH peptide was used for active targeting of a transgene in GnRHR expressing cells. The physiological characterizations of the prepared nanoparticle were investigated by proton nuclear magnetic resonance spectroscopy (1H NMR), Attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and Nanosizer. The prepared GnRH-CS was …
Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti
Validation Of Lamp-Lfd Ehrlichia Canis Dna Sensor Kit, Pipat Jirapiti
Chulalongkorn University Theses and Dissertations (Chula ETD)
Diagnosis of Canine Monocytic Ehrlichiosis is in light of anamesis, visualized cytoplasmic morulae, clinical signs and laboratory test result of platelet counts. The PCR technique is always a definitive confirmatory test of Ehrlichia canis infection. However, the drawback of PCRs test is crucially needed of laboratory equipments. This drawback is somehow enabled newly DNA based technology to be developed in order to eliminate laborious thermocycler and gel electrophoresis. The LAMP-LFD is on focus by using a single temperature to amplify DNA and no gel electrophoresis involved to detect DNA product. LAMP-LFD is included in DNAsensor test kit that recently developed …
The Role Of Ancestral Halls And Ancestral Worship In Chinese Clan Associations In Thailand As Forms Of Cultural Integration In The Age Of Globalization, Ying Zhang
Chulalongkorn University Theses and Dissertations (Chula ETD)
This dissertation focuses on studying the relationship between the ancestral hall and ancestral worship of Thai-Chinese clan associations in the context of contemporary Thai society, Thai local culture and the era of globalization. The research data mainly derives from the journals of the Thai-Chinese communities, news reports, on-site investigations and interviews. This study indicates that the Thai-Chinese had been living in Thai society and they had established Chinese traditional cultural practices in Thailand and enriched the culture of Thailand. With the development of contemporary Thai society, Thai-Chinese community associations have been transformed into non-governmental organizations and have become part of …
The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya
The Effect Of Monosodium Glutamate On Brain, Liver, Kidney, Testis, Ovary, Fertilization And Hatching Rate In Zebrafish (Danio Rerio), Chortip Sajjaviriya
Chulalongkorn University Theses and Dissertations (Chula ETD)
Monosodium glutamate (MSG) is composed of sodium salt and amino acids that is commonly used to enhance food taste. Although it is safe at consumption level, the adverse effect of MSG had been reported. The present research was intended to evaluate the effect of MSG on the brain, liver, kidney, testes, and ovaries of zebrafish (Danio rerio) which were exposed from embryo stage to adult stage, along with the analyzing of the fertilization rate and hatching rate of zebrafish embryos. From the observation of histopathological changing of different organs of zebrafish after exposed to 10, 100, and 1000 ppm MSG …
Synbiotic Effects Of Jerusalem Artichoke (Helianthus Tuberosus) And Lactobacillus Rhamnosus-Supplemented Diet On Growth Performance, Immunological Parameters And Protection Against Aeromonas Veronii Challenge In Juvenile Red Tilapias (Oreochromis Spp.), Mariya Sewaka
Chulalongkorn University Theses and Dissertations (Chula ETD)
Synbiotics, a synergistic combination of probiotics and prebiotics, are now highlighted as one of the most practical nutritional supplements in red tilapia farms. The aim of the present study was to assess the effect of the dietary inclusion of Jerusalem artichoke, Lactobacillus rhamnosus, or their combination, on serum biochemical, growth performance, intestinal morphology, immune parameters, intestinal bacterial count and protection against Aeromonas veronii in juvenile red tilapia (Oreochromis spp.). One hundred and eighty male red tilapias (average body weight of 14.05±0.42 g) were distributed into six 1000-liter tanks containing water under continuous aeration and an average temperature of 25–28°C. Tilapias …
The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad
The Development Of Elisa Kit To Detect Antibody Response Against Porcine Epidemic Diarrhea Virus From Colostrum And Milk, Anchalee Srijangwad
Chulalongkorn University Theses and Dissertations (Chula ETD)
Porcine epidemic diarrhea is caused by porcine epidemic diarrhea virus (PEDV), which causes swine watery diarrhea and higher mortality rates in piglets less than one week of age. Outbreaks of PED affect to economic loss, especially in a swine industrial country. Many strategies were used for preventing the outbreak and infection of PEDV, especially maternal antibody stimulation in pigs and then transfer to piglet through colostrum or milk. Thus, the investigation of antibody level for the situation on the farm is required. The method which convenient and rapid than viral neutralization (VN) test is an enzyme-linked immunosorbent assay (ELISA). The …
Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij
Efficacy Of Tetracycline And Enrofloxacin Against Wolbachia Spp. In Microfilaria Of Brugia Pahangi, Pimsiri Piromkij
Chulalongkorn University Theses and Dissertations (Chula ETD)
Brugia pahangi is a major causative agent of animal lymphatic filariasis, one of the neclected tropical disease. Recent studies have also indicated that B. pahangi can cause clinical infection in human, with clinical appearances which are consistent with human lymphatic filariasis. Nowadays, the recognition of Wolbachia as new alternative drug choice for treatment and control of lymphatic filariasis is the most important in anti-filarial chemotherapy. Since, Wolbachia play important roles, including the development, viability, fertility and fecundity of filarial parasites. Depletion of Wolbachia results in sterilization, stunting and death of filarial worms. In this study, we investigated the effects of …
Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen
Efficacy And Safety Evaluations Of Topical Proretinal Nanoparticles, Benchaphorn Limcharoen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Retinal (retinaldehyde) is one of natural vitamin A metabolites. It is widely used in clinical dermatology such as acne, acne scar, photoaging, wrinkles, psoriasis, skin neoplasia and seborrheic dermatitis. Retinal is a pivotal key to regulate keratinocyte proliferation and differentiation in the epidermis resulting in epidermal thickening and inhibit collagen destruction in the dermis. However, topical application of retinal is still irritative to the skin and chemically and photochemically unstable. Topically applied retinal can induce a retinoid dermatitis. This inflammation is induced by an overload of non-physiological amounts of exogenous retinoic acid in the skin. The adverse effects and physicochemical …
Genome Characterization Of Quinolone Resistance Associated Genes Of Flavobacterium Columnare Isolated From Columnaris Diseased Asian Sea Bass (Lates Calcarif)Er), Putita Chokmangmeepisarn
Genome Characterization Of Quinolone Resistance Associated Genes Of Flavobacterium Columnare Isolated From Columnaris Diseased Asian Sea Bass (Lates Calcarif)Er), Putita Chokmangmeepisarn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Flavobacterium columnare is Gram negative bacteria which caused columnaris disease in various kinds of freshwater fishes. This study is the first report of F. columnare infection in freshwater culturing Asian sea bass in Thailand. Phenotypic characterization, antimicrobial susceptibility test and quinolone resistant-associated genes of F. columnare were performed. A total 15 of F. columnare were isolated from diseased fishes and phylogenetic analysis revealed that these isolates were belonged to genetic group 2 and 4. From disk diffusion test results, 5 and 6 isolates were resistant to oxolinic (OA) and nalidixic acid (NA) respectively. The highest MIC values to OA and …
Surveillance Of Influenza A Viruses In A Live Bird Market, Yangon, Myanmar During 2017-2018, Khin Thurain
Surveillance Of Influenza A Viruses In A Live Bird Market, Yangon, Myanmar During 2017-2018, Khin Thurain
Chulalongkorn University Theses and Dissertations (Chula ETD)
Live bird markets play a significant role in highly pathogenic avian influenza (HPAI) virus spread and transmission. In Myanmar, the first HPAI-H5N1 outbreak was reported in 2006. Since 2014, routine influenza A virus surveillance in LBMs have been conducted in Myanmar by the Livestock Breeding and Veterinary Department in cooperation with FAO. However, there is limited information on virus characterization and evolution of influenza viruses in Myanmar. The objectives of this thesis were to detect influenza virus subtypes circulating in different poultry species from Mingalar-Taung-Nyunt live bird market (MTN-LBM) and to determine genetic characteristics and genetic diversity of influenza A …
Appropriate Campylobacter Detection Method And Genetic Variation Of Campylobacter Jejuni In Broilers, Natnicha Phetsri
Appropriate Campylobacter Detection Method And Genetic Variation Of Campylobacter Jejuni In Broilers, Natnicha Phetsri
Chulalongkorn University Theses and Dissertations (Chula ETD)
Campylobacter has been known as an important cause of gastroenteritis in humans. The primary source is raw or undercooked poultry meat. Previous study showed that Campylobacter isolated from slaughterhouses were associated with Campylobacter isolated from broiler farms. Thus, detection of Campylobacter flock status and sorting flocks prior to slaughtering processes may help prevent Campylobacter contamination between Campylobacter-positive and negative flocks during slaughtering processes. Unfortunately, appropriate sample type and isolation method have not been clearly specified for Campylobacter detection at the farm level. Because Campylobacter are fastidious bacteria, improper detection method can attribute to false negative results. Therefore, the objectives of …
Development Of Reverse Transcription Loop-Mediated Isothermal Amplification Combine With Lateral Flow Device As A Detection Assay For Swine Influenza Virus, Albarriyati Ummi Asih
Development Of Reverse Transcription Loop-Mediated Isothermal Amplification Combine With Lateral Flow Device As A Detection Assay For Swine Influenza Virus, Albarriyati Ummi Asih
Chulalongkorn University Theses and Dissertations (Chula ETD)
Swine influenza causes high morbidity and low mortality in pigs. The disease spreads rapidly in pig farms causing the delay of pig weight to reach market. Moreover, pigs play important role as "mixing vessel" of influenza viruses. Pigs can support infection and replication of influenza viruses from avian, human and swine origins. These lead to major concerns of the important of swine influenza which are not only the economic impacts but also the human health. There is the need of accurate and rapid diagnosis for swine influenza virus (SIV) to minimize further spreading of the viruses in pig population and …
Pedv Monitoring Using Oral Fluid, Feces And Surface Swab Samples After The Ped Outbreak, Busayamas Jantrasakul
Pedv Monitoring Using Oral Fluid, Feces And Surface Swab Samples After The Ped Outbreak, Busayamas Jantrasakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
A total of 220 pooled samples from 3 collection times were conducted. Eighty pooled samples from the first collection at 1 month after PED outbreak (1MAO) included 10 pooled oral fluid samples, 30 pooled fecal samples and 40 pooled surface swab samples. Eighty-five pooled samples from the second collection at 2MAO included 10 pooled oral fluid samples, 30 pooled fecal samples and 45 pooled surface swab samples. Fifty-five pooled samples from the third collection at 8MAO included 5 pooled oral fluid samples, 15 pooled fecal samples and 35 pooled surface swab samples. All samples collected from the PED-affected swine farm …
Phenotypic And Genotypic Characteristics Of Extended-Spectrum Β-Lactamase (Esbl) Production And Colistin-Resistance In Salmonella Enterica And Escherichia Coli Isolated From Pigs And Their Meat Products In The Border Provinces Between Thailand And Cambodia, Lao Pdr And Myanmar, Kyaw Phyoe Sunn
Chulalongkorn University Theses and Dissertations (Chula ETD)
A total of 809 samples of pig rectal swab from slaughterhouses (n=441) and pork from retail market (n=368) were collected in the border provinces among Thailand, Cambodia, Lao PDR and Myanmar between October 2016 and March 2017. The objective of this study was to determine resistance to extended-spectrum ß-lactams (ESBLs) and colistin in Salmonella enterica and Escherichia coli. A total of Salmonella (n=463) and E. coli (n=767) were collected and determined for the ESBL-production and for the Minimum Inhibitory Concentrations (MICs) of colistin and; the presence of ESBL gene and mcr gene. The results showed that the prevalence of Salmonella …
Genetic Characteristics Of Avian Influenza Viruses Isolated From Ducks In Java Island, Indonesia Year 2015-2017, Lestari -
Chulalongkorn University Theses and Dissertations (Chula ETD)
Avian influenza becomes public health concern over years due to the serious impacts in both animal and human health. This study aimed to identify and characterize avian influenza viruses isolated from ducks in Java Indonesia during 2015-2017. Total 50 samples of previously identified as avian influenza viruses were acquired from the virus/culture collections of Disease Investigation Center (DIC) Wates Yogyakarta, Indonesia. The samples were recovered from either the avian influenza surveillance or avian influenza outbreaks in ducks in 3 provinces, East Java (n=26), Central Java (n=16), and Yogyakarta (n=8). Then the samples were processed for influenza A virus screening by …
Genome Characterization Of Hahella Chejuensis Strain Hn01, A Pathogen Of Red Egg Disease In Tilapia (Oreochromis Sp.), Putu Cri Devischa Gallantiswara
Genome Characterization Of Hahella Chejuensis Strain Hn01, A Pathogen Of Red Egg Disease In Tilapia (Oreochromis Sp.), Putu Cri Devischa Gallantiswara
Chulalongkorn University Theses and Dissertations (Chula ETD)
Red eggs disease is an emerging disease occurred in Tilapia hatcheries which caused by a Gram-negative bacterium called Hahella chejuensis HN01. The disease infects to all the stage of fish eggs and reduces the hatchability. However, there are limited study about the bacterial pathogenicity. In this study, we analyzed the phylogenetic relationship and characterized the virulence traits of Hahella chejuensis by using genomic approach. The bacterial genome was sequenced using Illumina Miseq platform. The phylogenetic tree based on several housekeeping genes confirmed that the bacterium was belong to Genus Hahella and species chejuensis. the Average Nucleotide Identity calculation with the …
Detection Of Antimicrobial Resistance Determinants In Vibrio Parahaemolyticus Isolated From Cultivated Oysters And Estuarine Waters, Winn Khant
Chulalongkorn University Theses and Dissertations (Chula ETD)
In this study, we aimed to detect antimicrobial resistance determinants and virulence factor genes in V. parahaemolyticus isolates from cultivated oysters and estuarine waters in southern Thailand. A total of 594 V. parahaemolyticus isolates were collected from pooled oysters (n=361) and estuarine waters (n=233). The samples were collected monthly between March 2016 and February 2017 from Thap Put district, Phang Nga province in southern Thailand. Confirmation of V. parahaemolyticus was carried out by PCR assay detecting species-specific (tlh) gene and the presence of virulence genes (tdh and trh). Antimicrobial susceptibility test was performed in eight antimicrobials, and the occurrence of …
Biomechanical And Biological Properties Of Cryopreserved Canine Amniotic Membrane, Nathawan Withavatpongtorn
Biomechanical And Biological Properties Of Cryopreserved Canine Amniotic Membrane, Nathawan Withavatpongtorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Amniotic membrane (AM) is the innermost fetal membrane. Due to its many known properties, human AM is a favorable corneal graft. Cryopreservation at -80ºC maintains most of biological properties. Due to shortage of supply, AM of other species are studied. The objective of this study is to explore the biomechanical and biological properties of canine AM (CAM) after cryopreservation for 7 and 30 days. CAMs were collected from healthy bitches undergoing cesarean sections. After preservation, they were tested for tensile strength by Universal Testing Machine, transparency by spectrophotometer, sterility by microbial culture, cell viability by trypan blue staining, and histological …
The Efficiency Of Pcso-524 On Feline Osteoarthritis Associated With Chronic Kidney Disease, Pemika Dulyapraphant
The Efficiency Of Pcso-524 On Feline Osteoarthritis Associated With Chronic Kidney Disease, Pemika Dulyapraphant
Chulalongkorn University Theses and Dissertations (Chula ETD)
Twenty-six osteoarthritic cats concurrent with chronic kidney disease (CKD) enrolled in this study. All cats were divided randomly into 2 groups; control group (n=12) received placebo and treatment group (n=14) received PCSO-524 for 60 days. Cats had verified stable CKD stage II and had treated and followed up for CKD more than 3 months were included in our study. Before starting the study (day 0), all cats were taken the coxofemoral joint radiographic imaging. Only cats with the radiographic osteoarthritic lesion(s) were recruited. All of them had blood profile check-up, urinalysis, blood pressure measurement, lameness score assessment, acute and chronic …
Chondroprotective Efficacy Of Pcso-524 On Canine Osteoarthritis Secondary To Medial Patellar Luxation, Ratthanan Sathienbumrungkit
Chondroprotective Efficacy Of Pcso-524 On Canine Osteoarthritis Secondary To Medial Patellar Luxation, Ratthanan Sathienbumrungkit
Chulalongkorn University Theses and Dissertations (Chula ETD)
Fifty stifles from Pomeranians and Chihuahuas with over five years old were enrolled in this study, which are 8 normal stifles and 42 medial patellar luxation (MPL) stifles. All MPL stifles were assigned randomly into 2 groups, including control and treatment groups. The control group was received placebo daily for 16 weeks, while treatment group was fed with PCSO-524 for 16 weeks. Lameness score, ultrasonographic findings, radiographic OA score and owner questionnaire (cBPI) were assessed at pre-treatment (D0) and post-treatment at week 2, 4, 8, 12 and 16. The ultrasonographic evaluations consisted of synovial fluid, articular cartilage, bone surface and …
Comparative Clinical Outcomes Of Elongated Soft Palate In Brachycephalic Dogs By Surgical Treatment Using The Ultrasonic Scalpel And Bipolar Sealing Device Techniques, Varit Wijitratanagorn
Comparative Clinical Outcomes Of Elongated Soft Palate In Brachycephalic Dogs By Surgical Treatment Using The Ultrasonic Scalpel And Bipolar Sealing Device Techniques, Varit Wijitratanagorn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Brachycephalic airway obstruction syndromes (BAOS) are the most common respiratory problems in brachycephalic dogs. Surgical treatment which are staphylectomy and alaplasty is commonly used for correction primary lesions of BAOS. The purpose of this study is to compare clinical outcome of post staphylectomy using ultrasonic scalpel and bipolar sealing devices. Twenty brachycephalic dogs were included for staphylectomy and randomly separated into two groups. Surgical time, perioperative blood loss, pain score and clinical score of respiratory function were recorded at day 1 7 14 21 and 28 post-operative. The excised soft palate at day 0 and 21 was recorded lateral thermal …
Flood Damage Assessment: A Case Study In Bakan And Phnom Kravanh Districts, Pursat Province, Cambodia, Chhunleang Rorm
Flood Damage Assessment: A Case Study In Bakan And Phnom Kravanh Districts, Pursat Province, Cambodia, Chhunleang Rorm
Chulalongkorn University Theses and Dissertations (Chula ETD)
Flood is still a major climate hazard in Pursat province, a potential province for agricultural development in Cambodia. The consequences of this water-related disaster are social problems such as poverty, food insecurity and health problems, which indirectly prolong the growth of the country's economy. To propose a proper flood mitigation measure, flood damage assessment is considered as a fundamental step to implement so that the value of elements at risk is initially evaluated. The objectives of this research are to assess flood damage in agriculture and affected people in Bakan and Phnom Kravanh districts, Pursat province from 2000 to 2014, …
Drought Assessment For The Greater Baribo Basin In Cambodia, Kimhuy Sok
Drought Assessment For The Greater Baribo Basin In Cambodia, Kimhuy Sok
Chulalongkorn University Theses and Dissertations (Chula ETD)
Cambodia is a developing country. The development and economic of the country rely mainly on agricultural production. Cambodia is a major exporter in the world rice market. The Tonle Sap basin covers about 44% of country. Rice production in the Tonle Sap basin is a main driver for national economic and social development. Due to natural variability and climate change, many forms of the natural disaster such as heavy storm, flood, and drought have occurred in the Tonle Sap basin. Over the recent decades, increased attention has been drawn to drought due to the tendency of rainfall decline. The Royal …
Micro-Scale Flood Hazard Assessment In Phnom Penh, Cambodia, Naichy Sea
Micro-Scale Flood Hazard Assessment In Phnom Penh, Cambodia, Naichy Sea
Chulalongkorn University Theses and Dissertations (Chula ETD)
Water-related disasters in urban area, especially urban floods have become more frequent and severe. This leads to loss of life, infrastructure damage, business interruption as well as difficulties in conducting daily activities. Phnom Penh, the capital city of Cambodia, has frequently experienced significant rainfall-flood events during rainy season. Without proper prevention and mitigation and management of urban drainage system, Phnom Penh is expected to confront with the current and future challenge of water-related disaster. To address this urban flood issue, flood modeling could be used to assess flood severity and make a visual representation of the urban flood hazard as …
Changes Of Hypothalamic-Pituitary-Testicular Axis In Male Rats During Cognitive Impairment, Patteera Wititsuwankul
Changes Of Hypothalamic-Pituitary-Testicular Axis In Male Rats During Cognitive Impairment, Patteera Wititsuwankul
Chulalongkorn University Theses and Dissertations (Chula ETD)
From the previous reports denoting that hypothalamus regulating reproductive function via hypothalamic-pituitary-testicular (HPT) axis, and hippocampus controlling learning and memory capacity can synthesize reproductive hormones, and that cognitive impairment particularly occurs during reproductive senescence, it leads to the following research questions; i) which system first enters the aging stage and ii) how the changes are related. Male rats at the ages of 4, 6, 8, 10 and 12 months old were subjected for this study. Blood samples were collected for serum testosterone (T) and luteinizing hormone (LH) assays by enzyme-linked immunosorbent assay (ELISA) techniques. Testes, seminal vesicle, prostate gland and …
Effects Of Alpha-Mangostin On Hematopoiesis In Zebrafish Danio Rerio (Hamilton, 1822) Embryos, Wannakarn Kitipaspallop
Effects Of Alpha-Mangostin On Hematopoiesis In Zebrafish Danio Rerio (Hamilton, 1822) Embryos, Wannakarn Kitipaspallop
Chulalongkorn University Theses and Dissertations (Chula ETD)
Alpha-mangostin (AM) is in the xanthone group and a main compound extracted from mangosteen (Garcinia mangostana Linn.). It is effective in antioxidant, antimicrobe and anticancer activities. However, the underlying side effects on normal cells, especially in hematopoiesis have not been investigated completely. In this research, it was aimed to elucidate the possible effects of AM on hematopoiesis using zebrafish (Danio rerio) embryos as a representative model. The results showed that AM could cause the zebrafish embryonic mortality with the concentration dependent manner. The median lethal concentration (LC50) of AM at 72 h was 5.75 ± 0.26 µM. In addition, AM …