Digital Commons Network^™

Frost450, A Novel Microtubule Targeting Agent: Resistance And Cross-Resistance In An Ovarian Cancer Cell Line, Jonathan Chancellor Fox

Undergraduate Honors Theses

Drug resistance remains problematic for chemotherapy treatments. As primary treatment strategies tend to lose potency against cancer, there is a need for treatment options that overcome drug resistance mechanisms. FROST450, a novel microtubule destabilizing agent, has proven anticancer effects that overcome taxane and multidrug resistance. However, to better understand the clinical potential of FROST450, in this study we examine the mechanisms and implications of acquired FROST450 resistance in an A2780 ovarian cancer cell line. Results indicate FROST450 resistance is associated with increased mitochondrial respiration and with changes in gene sequence or expression level of proteins associated with microtubules, and that …

A Hermeneutic Phenomenological Study Of Teen Mothers Who Graduated From An Alternative School, Olivia P. Modesto 5721808

The Qualitative Report

Many studies support the recurring theme that due to early childbearing, the education of teen mothers is jeopardized. Negative stereotypes towards them also prevail representing the view that teen mothers are wayward, divergent, and burdensome to society. However, there is support from the literature that the majority of them maintain career and educational aspirations. Moreover, access of pregnant minors and teen mothers to public education is guaranteed by law. With this in view, the researcher explored the educational experiences of teen mothers, particularly those who chose to enroll in and eventually graduated from an alternative public school that exclusively serves …

Mobility In Syntax: On Contextuality In Labeling And Phases, Yong Suk Yoo

Doctoral Dissertations

This dissertation investigates how mobility of syntactic elements is affected by the theory of labeling (Chomsky 2013) and the theory of phases (Chomsky 2000, 2001), with the special attention paid to the contextuality of labeling and phases, and traditional adjunction.

Control Theory: The Double Pendulum Inverted On A Cart, Ian J P Crowe-Wright

Mathematics & Statistics ETDs

In this thesis the Double Pendulum Inverted on a Cart (DPIC) system is modeled using the Euler-Lagrange equation for the chosen Lagrangian, giving a second-order nonlinear system. This system can be approximated by a linear first-order system in which linear control theory can be used. The important definitions and theorems of linear control theory are stated and proved to allow them to be utilized on a linear version of the DPIC system. Controllability and eigenvalue placement for the linear system are shown using MATLAB. Linear Optimal control theory is likewise explained in this section and its uses are applied to …

Gardner-Webb English Major Analyzes Gendered Language In Sport Hunting Community, Office Of University Communications

Gardner-Webb NewsCenter Archive

The town of Norwood, N.C., is situated on the Pee Dee River and near the Uwharrie National Forest, offering residents several places to hunt and fish. Gardner-Webb University senior Ally Ward grew up there and took up bow hunting when she was in middle school. The hobby began as a bonding time for Ward and her dad.

Delivering And Serving Hope, Haley Haring

First-Year Seminar Posters (COE 102/103)

DASH focuses on 2 social issues mainly that overlap each other, they provide for those who have food insecurities and the homeless population. Overall it is more about providing food for the homeless population.

Spread The Word Nevada, Leonardo Gonzalez

Second-Year Seminar Posters (COE 202)

Spread the Word addresses the issue of literacy among children, in particular those who come from low income households.

Tcmi Church, Rosa Gonzalez

Second-Year Seminar Posters (COE 202)

TCMI has been working to stop hunger here in the Las Vegas community.

Ayala V. Robert J. Meyers Farms, Inc. Appellant's Brief Dckt. 46186

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Installments, Special Issue, Winter Break 2018, Renee Montgomery

Libraries' Newsletters

No abstract provided.

The Structure Of The Treasury Market: What Are We Learning?, Lael Brainard

Documents

No abstract provided.

Memorial Service For Burt Feintuch, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

There’S Evil Sitting On The Porch, Alexa Bills

USU Student Folklore Fieldwork

This is a story that my seminary teacher, he was seminary teacher in Spanish Fork. [Uh] when I was a sophomore in high school at Spanish Fork High school. He was, I can’t remember his name. But he was a really funny seminary teacher, I really like him. He [Uh] had some stories to tell. And [uh] one of the stories, he was from Las Vegas, I guess when he first got married he, [uh] when he was a new seminary teacher, he [uh] came home from work one day and he said he felt like just pure evil when …

Weather Watchers, Taylor Mcdougal

USU Student Folklore Fieldwork

I didn’t really have any secret languages that I spoke when I was a kid but I used to ride on the bus with my friends and we’d do weather watchers and we’d all talk to each other there. One of my friends would speak Japanese and I would speak Spanish and another one of my friends would speak with an English accent and we’d just talk to each other.

Me: did you guys actually know how to speak Japanese and Spanish?

Oh no. no we would just pretend to speak how we thought that other languages sounded and we …

Switching Beds, Alexa Bills

USU Student Folklore Fieldwork

This is [uh] I grew up in Nephi Utah in the 70’s. We lived in a house that was moved to Nephi from [uh] I think it was Topaz, or out in the west desert of Utah that was a Japanese internment camp during [uh] world war two. It was a two bedroom house, so my parents lived in one room, and my brother and sister and I lived in the other room. We had a bunk bed and a single bed on the floor, so there were three beds in the room. [uh] So we were probably, I would …

Enabling Auditing And Intrusion Detection Of Proprietary Controller Area Networks, Brent C. Stone

Theses and Dissertations

The goal of this dissertation is to provide automated methods for security researchers to overcome ‘security through obscurity’ used by manufacturers of proprietary Industrial Control Systems (ICS). `White hat' security analysts waste significant time reverse engineering these systems' opaque network configurations instead of performing meaningful security auditing tasks. Automating the process of documenting proprietary protocol configurations is intended to improve independent security auditing of ICS networks. The major contributions of this dissertation are a novel approach for unsupervised lexical analysis of binary network data flows and analysis of the time series data extracted as a result. We demonstrate the utility …

Chris Harris' Campus Visit Became An Extended Stay, Thomas M. Columbus

Materials from the University of Dayton Magazine Website

Pope Francis portrays the humanity of the papacy with pastoral spirit.

Faulkner's Media Romance, Julian Murphet., James Altman

English Faculty Research

No abstract provided.

Fear And Career Decision-Making Difficulties: Guiding Individuals With Career Indecisiveness, Jordan Hanks

Student Works

Individuals with fear-based career indecisiveness exhibit extreme career decision-making difficulties (CDD) which prevent them from successfully making career decisions. Fear must be recognized as a significant contributor to indecisiveness in order to aid those with fear-based career indecisiveness. Career guidance professionals may help indecisive individuals by first identifying the causes of indecisiveness and the decision-making fear. Career indecisiveness may have either low career self-efficacy or low emotional intelligence as a contributor, each of which impact individuals differently. Career indecisiveness also involves either a fear of failure or a fear of commitment, which may contribute to CDD. Guidance for these individuals …

The Free Press Vol. 50, Issue No. 10, 12-03-2018, Julie Pike

Free Press, The

Renovations planned for Brooks Dining Hall -- Student Senate working to raise activity fee -- Students share their internship experience -- Council promotes diversity and inclusion at USM

Lanthorn, Vol. 53, No. 16, December 3, 2018, Grand Valley State University

Volume 53, July 9, 2018 - June 10, 2019

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

In Search Of The Recognition Of Expatriate Complexity: Interpretative Phenomenological Analysis Of Psychotherapy Experience, Mojca Filipic Sterle, Lesley L. Verhofstadt, Pam Bell, Jan De Mol

The Qualitative Report

Expatriates experiencing emotional distress and a call for globally oriented psychotherapy receive an increased focus in the research agendas. That one may better understand how expatriates may be helped in times of distress, the insight in their actual psychotherapy experience may serve as a valuable avenue. The aim of this qualitative study was to illuminate the lived experience of psychotherapy and the meaning that expatriates attributed to these experiences within their expatriate context. Semi-structured interviews were utilized for the data collection and Interpretative Phenomenological Analysis (IPA) was employed for data analysis. The following themes emerged from the expatriates’ narratives about …

Representations Of Immigrants In Young Adult Literature, Frances Augusta Ramos Verbruggen

Dissertations and Theses

This study was conducted to determine how immigrants and the immigration experience are represented in current young adult (YA) literature. In the study, I asked the following questions: Who are the immigrant characters in recent YA books? Why do they come? How do they experience immigration? How are they perceived or treated by others? A content analysis methodology was used to examine, from a critical literacy viewpoint, recent young adult novels with immigration themes. Data were analyzed by identifying and interpreting patterns in themes across 22 YA novels with immigrant protagonists or other important characters, published between 2013 and 2017. …

Stress Management And Cardiovascular Health: Perceptions Of University Employees, Janki Rashmikant Patel

Honors Capstone Projects and Theses

No abstract provided.

Analyzing Self-Care Initiative Of Nursing Students, Lawren Murray Tachias

Honors Capstone Projects and Theses

No abstract provided.

“Are You Accepting New Patients?” A Pilot Field Experiment On Telephone-Based Gatekeeping And Black Patients’ Access To Pediatric Care, Tamara Leech, Amy Irby-Shasanmi, Anne L. Mitchell

Department of Public Health Scholarship and Creative Works

Study Objectives

To determine whether the name and accent cues that the caller is Black shape physician offices’ responses to telephone‐based requests for well‐child visits.

Method and Data

In this pilot study, we employed a quasi‐experimental audit design and examined a stratified national sample of pediatric and family practice offices. Our final data include information from 205 audits (410 completed phone calls). Qualitative data were blind‐coded into binary variables. Our case‐control comparisons using McNemar's tests focused on acceptance of patients, withholding information, shaping conversations, and misattributions.

Findings

Compared to the control group, “Black” auditors were less likely to be told …

Comparing Reunified And Residential Care Facility Children's Wellbeing In Ghana: The Role Of Hope, Spencer L. James, Jini L. Roby

Faculty Publications

The U.N. Convention on the Rights of the Child (UNCRC) stipulates children are entitled to “a family environment…of happiness, love and understanding”. Recent work on deinstitutionalization of children from residential care has found important child wellbeing differences, particularly around hope. Using data from Ghana—a country that has initiated reintegration of children from residential care facilities, therefore providing a natural opportunity for comparative research—we used hope, whether the child has been reunified with family/caregivers or remained in the care facility, and a statistical interaction of the two, along with controls, to predict the Child Status Index, an internationally-established measure of child …

Factors Influencing Behavioral Intention To The Use Of Information And Communication Technology (Ict) Among Students Of Federal Polytechnic, Ilaro. Ogun State. Nigeria, Oludayo Babalola

Library Philosophy and Practice (e-journal)

ABSTRACT

The significance of Information and Communication (ICT) in Polytechnic education cannot be over-emphasized. The introduction of ICTs has tremendously assisted the libraries in their routine duties such as charging and discharging library materials, checking in and checking out users, library registration, recall of library materials indexing, cataloguing and classification The aim of the study is to examine the factors that influence the behavioral intention to use ICT among Polytechnic students in Nigeria. The study adopted the Unified Theory of Acceptance and Use of Technology (UTAUT) constructs. Extant Literature on the UTAUT and ICT influence the behavioral intention to use …

Let's Be-Gin 氈氈自喜, Alice Franklin

AMBROSIA 客道 : The Magazine of The International Culinary Institute

This juniper-flavoured liquor has experienced a meteoric rise in popularity, thanks to the craft spirits movement and an explosion of botanical experimentation. Now, with a first distillery set to open in Hong Kong, the trajectory points ever higher.

手工精釀烈酒的熱潮， 加上專家不停進行各種草本植物配方的試驗，造就了近年以杜松子調味的氈酒人氣急升。今天，香港也迎來 首間氈酒蒸餾廠，氈酒的火紅程度可謂一時無兩。

World's Best 世界之最, Xanthe Clay

AMBROSIA 客道 : The Magazine of The International Culinary Institute

Chef Massimo Bottura may run the world's best restaurant, but his influence is felt far beyond the kitchen as he uses his talent and foresight to effect change.

執掌全球最佳餐廳的名廚Massimo Bottura走出廚房，憑其烹飪才華與先見之明，致力讓世界變得更美好。