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2018

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Smart Text Tool For Capturing And Sharing Visual Content Dec 2018

Smart Text Tool For Capturing And Sharing Visual Content

Defensive Publications Series

A system, method and computer readable media to facilitate capturing and sharing images through a device application is disclosed. The application includes smart and AR text tools for automatically placing the text in the image and choosing the color or the background of the text based on one or more rules. The rules may be based on analysis of the image such as facial recognition, contrast detection, color detection and content detection. The application additionally includes an augmented reality text filter for text placement on a capture screen. The AR text tool allows user to add expressive motion elements to …


Automated Augmented Reality Context Stickers Dec 2018

Automated Augmented Reality Context Stickers

Defensive Publications Series

The disclosure relates to a method, system and computer readable media for automatically placing relevant augmented reality (AR) stickers in user’s field of view on opening a device application. The method places dynamic location, weather or time stickers on the ground plane or above the field of view, once the user opens the camera and also during the capture flow of moments. The user may either flick or dismiss them, or press-and-hold the stickers to move them to a desired position and then capture. The method brings the most used 2D post-capture sticker learnings to life automatically. The method gives …


Growth Characteristics Of Newly Isolated Indonesian Microalgae Under Different Salinity, Wa Iba, Michael A. Rice, Lucie Maranda, Gary H. Wikfors Dec 2018

Growth Characteristics Of Newly Isolated Indonesian Microalgae Under Different Salinity, Wa Iba, Michael A. Rice, Lucie Maranda, Gary H. Wikfors

Fisheries, Animal and Veterinary Sciences Faculty Publications

The aim of this study was to investigate the growth characteristics of microalgae strains isolated from Kendari Bay and the Wanggu River estuary, Indonesia. The growth of the isolates, denoted as Kb1-2, Kb1-3, Kb1-5, and Kb2-6, were evaluated under controlled conditions. A batch culture experiment of these strains except Kb2-6 was conducted for 15 days under salinity levels of 20, 25, 30 and 35 gL-1. Tetraselmis chui, Tisochrysis lutea and Chaetocero sneogracile were also culture and used as the growth references. Cell density was measured every day and cell size was measured from 50 live cells during the logarithmic …


Effects Of Aging Time And Cooking Degree On Volatile Flavors Of Beef, Wang Hengpeng, Wu Peng, Chen Shengsu, Tu Mingliang, Gao Ziwu, Xie Jing, Yang Tianyi, Chen Chang, Meng Xiangren Dec 2018

Effects Of Aging Time And Cooking Degree On Volatile Flavors Of Beef, Wang Hengpeng, Wu Peng, Chen Shengsu, Tu Mingliang, Gao Ziwu, Xie Jing, Yang Tianyi, Chen Chang, Meng Xiangren

Food and Machinery

In order to study the effects of aging time, cooking degree and their interaction on beef flavor components, the longissimus dorsi of Simmental cattle in the process of aging time (3, 5, 7 d) were selected to make steaks of medium, medium well and well done. Volatile flavor components in different aging times and cooking degree were analyzed by headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS), explored the best aging time and cooking degree which were beneficial to flavor substances formated. Results showed that, a total of 50 volatile compounds were identified in each beef sample. The …


Studies On Curcumin And Cftr: Refutation And Recognition, Luan Jian, Cao Huanhuan, Zhou Xiaofu Dec 2018

Studies On Curcumin And Cftr: Refutation And Recognition, Luan Jian, Cao Huanhuan, Zhou Xiaofu

Food and Machinery

The research progress of curcumin stimulates mutant CFTR chloride channel since 2004 is summarizes in this review, and the process from discovery to refutation, from resistance to recognition of this theory are also discussed. Scientists prove that curcumin is a natural molecular activator of CFTR chloride channel, and plays an important role in the treatment of cystic fibrosis and the drug development, according the investigation of the experiment methods, mechanisms and pharmacokinetics. This review reveals the potential problems such as safe dose, and aims to provide references for cystic fibrosis drug research and development.


Dynamic Responses And Implications To Coastal Wetlands And The Surrounding Regions Under Sea Level Rise, Karim Alizad, Scott C. Hagen, Stephen C. Medeiros, Matthew V. Bilskie, James T. Morris, Len Balthis, Christine A. Buckel Dec 2018

Dynamic Responses And Implications To Coastal Wetlands And The Surrounding Regions Under Sea Level Rise, Karim Alizad, Scott C. Hagen, Stephen C. Medeiros, Matthew V. Bilskie, James T. Morris, Len Balthis, Christine A. Buckel

Faculty Publications

Two distinct microtidal estuarine systems were assessed to advance the understanding of the coastal dynamics of sea level rise in salt marshes. A coupled hydrodynamic-marsh model (Hydro-MEM) was applied to both a marine-dominated (Grand Bay, Mississippi) and a mixed fluvial/marine (Weeks Bay, Alabama) system to compute marsh productivity, marsh migration, and potential tidal inundation from the year 2000 to 2100 under four sea level rise scenarios. Characteristics of the estuaries such as geometry, sediment availability, and topography, were compared to understand their role in the dynamic response to sea level rise. The results show that the low sea level rise …


The Changes Intexture And Physicochemical Properties Of Giant Freshwater Prown (Macrobrachium Rosenbergii) During Frozen Storage, Liu Jiatong, Jiang Qixing, Yang Fang, Wang Bin, Xu Yanshun, Xia Wenshui, Xu Yan Dec 2018

The Changes Intexture And Physicochemical Properties Of Giant Freshwater Prown (Macrobrachium Rosenbergii) During Frozen Storage, Liu Jiatong, Jiang Qixing, Yang Fang, Wang Bin, Xu Yanshun, Xia Wenshui, Xu Yan

Food and Machinery

The texture and physicochemical properties of giant freshwater prawn during frozen storage were investigated in this study. The quality differences of frozen whole prawn and headless prawn were compared and analyzed by shear stress, myofibrillar fragmentation index, myofibrillar apparent diameter, TCA soluble peptide and total protease activity. The results showed that the shear force of prawn decreased with the extension of storage time. The shear force of frozen whole prawn decreased more rapidly than headless prawn. After 16 weeks, the shear force of frozen whole prawns and headless shrimp decreased by 36.81% and 25.40%. The myofibril fragmentation index and TCA …


Meral Spot Total Reflectance Signals Weapon Performance In The Mantis Shrimp Neogonodactylus Oerstedii (Stomatopoda), Amanda M. Franklin, Cassandra M. Donatelli, Casey R. Culligan, Eric D. Tytell Dec 2018

Meral Spot Total Reflectance Signals Weapon Performance In The Mantis Shrimp Neogonodactylus Oerstedii (Stomatopoda), Amanda M. Franklin, Cassandra M. Donatelli, Casey R. Culligan, Eric D. Tytell

Engineering Faculty Articles and Research

During animal contests over resources, opponents often signal their fighting ability in an attempt to avoid escalating to physical attack. A reliable signal is beneficial to receivers because it allows them to avoid injuries from engaging in contests they are unlikely to win. However, a signaler could benefit from deceiving an opponent by signaling greater fighting ability or greater aggressive intent than the signaler possesses. Therefore, the reliability of agonistic signals has long intrigued researchers. We investigated whether a colored patch, the meral spot, signals weapon performance in the stomatopod Neogonodactylus oerstedii. During fights over possession of refuges, stomatopods can …


Lifestyle Modifications: Coordinating The Trna Epitranscriptome With Codon Bias To Adapt Translation During Stress Responses, Cheryl Chan, Phuong Pham, Peter C. Dedon, Thomas J. Begley Dec 2018

Lifestyle Modifications: Coordinating The Trna Epitranscriptome With Codon Bias To Adapt Translation During Stress Responses, Cheryl Chan, Phuong Pham, Peter C. Dedon, Thomas J. Begley

Biological Sciences Faculty Scholarship

Cells adapt to stress by altering gene expression at multiple levels. Here, we propose a new mechanism regulating stress-dependent gene expression at the level of translation, with coordinated interplay between the tRNA epitranscriptome and biased codon usage in families of stress-response genes. In this model, auxiliary genetic information contained in synonymous codon usage enables regulation of codon-biased and functionally related transcripts by dynamic changes in the tRNA epitranscriptome. This model partly explains the association between synchronous stress-dependent epitranscriptomic marks and significant multi-codon usage skewing in families of translationally regulated transcripts. The model also predicts translational adaptation during viral infections.


Uab Joins Gilbert Family Foundation Initiative For Neurofibromatosis Type 1, Alicia Rohan Dec 2018

Uab Joins Gilbert Family Foundation Initiative For Neurofibromatosis Type 1, Alicia Rohan

Browse All News

No abstract provided.


Discerning Novel Splice Junctions Derived From Rna-Seq Alignment: A Deep Learning Approach, Yi Zhang, Xinan Liu, James N. Macleod, Jinze Liu Dec 2018

Discerning Novel Splice Junctions Derived From Rna-Seq Alignment: A Deep Learning Approach, Yi Zhang, Xinan Liu, James N. Macleod, Jinze Liu

Computer Science Faculty Publications

Background: Exon splicing is a regulated cellular process in the transcription of protein-coding genes. Technological advancements and cost reductions in RNA sequencing have made quantitative and qualitative assessments of the transcriptome both possible and widely available. RNA-seq provides unprecedented resolution to identify gene structures and resolve the diversity of splicing variants. However, currently available ab initio aligners are vulnerable to spurious alignments due to random sequence matches and sample-reference genome discordance. As a consequence, a significant set of false positive exon junction predictions would be introduced, which will further confuse downstream analyses of splice variant discovery and abundance estimation.

Results: …


Ochre And Pigment Use At Hohle Fels Cave: Results Of The First Systematic Review Of Ochre And Ochre-Related Artefacts From The Upper Palaeolithic In Germany, Elizabeth C. Velliky, Martin Porr, Nicholas J. Conard Dec 2018

Ochre And Pigment Use At Hohle Fels Cave: Results Of The First Systematic Review Of Ochre And Ochre-Related Artefacts From The Upper Palaeolithic In Germany, Elizabeth C. Velliky, Martin Porr, Nicholas J. Conard

KIP Articles

Studies of modern carnivore accumulations of bone (i.e., neo-taphonomy) are crucial for interpreting fossil accumulations in the archaeological and paleontological records. Yet, studies in arid regions have been limited in both number and detailed taphonomic data, prohibiting our understanding of carnivore bone-accumulating and -modifying behavior in dry regions. Here, we present a taphonomic analysis of an impressive carnivore-accumulated bone assemblage from the Umm Jirsan lava tube in the Harrat Khaybar region, Saudi Arabia. The size and composition of the bone accumulation, as well as the presence of hyena skeletal remains and coprolites, suggest that the assemblage was primarily accumulated by …


Using Physical Contact Heterogeneity And Frequency To Characterize Dynamics Of Human Exposure To Nonhuman Primate Bodily Fluids In Central Africa, Victor Narat, Mamdou Kampo, Thibut Heyer, Stephanie Rupp, Philippe Ambata, Richard Njouom, Tamara Giles-Vernick Dec 2018

Using Physical Contact Heterogeneity And Frequency To Characterize Dynamics Of Human Exposure To Nonhuman Primate Bodily Fluids In Central Africa, Victor Narat, Mamdou Kampo, Thibut Heyer, Stephanie Rupp, Philippe Ambata, Richard Njouom, Tamara Giles-Vernick

Publications and Research

Emerging infectious diseases of zoonotic origin constitute a recurrent threat to global health. Nonhuman primates (NHPs) occupy an important place in zoonotic spillovers (pathogenic transmissions from animals to humans), serving as reservoirs or amplifiers of multiple neglected tropical diseases, including viral hemorrhagic fevers and arboviruses, parasites and bacteria, as well as retroviruses (simian foamy virus, PTLV) that are pathogenic in human beings. Hunting and butchering studies in Africa characterize at-risk human social groups, but overlook critical factors of contact heterogeneity and frequency, NHP species differences, and meat processing practices. In southeastern Cameroon, a region with a history of zoonotic emergence …


The Weekly Challenger, December 27, 2018, The Weekly Challenger, Et Al Dec 2018

The Weekly Challenger, December 27, 2018, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The December 27, 2018, issue of The Weekly Challenger.


Small Rna Mgrr Regulates Sensitivity Of Escherichia Fergusonii To Oxidative Stress, Austin Paul Wright Dec 2018

Small Rna Mgrr Regulates Sensitivity Of Escherichia Fergusonii To Oxidative Stress, Austin Paul Wright

Dissertations and Theses

Non-coding small RNAs (sRNAs) are integral to post-transcriptional gene regulation in bacteria. The function of an sRNA is dependent on both secondary structure and the sequence of its unstructured seed region. The sRNA seed region typically base-pairs with target mRNAs to down-regulate the expression of target genes by blocking the ribosome-binding site or by promoting RNase-mediated degradation of the sRNA-mRNA complex. sRNAs have also been shown to increase expression of target genes by releasing RNA secondary structures that block ribosome-binding sites. Selective pressure to maintain sRNA function conserves the sequence of the sRNA seed region, but mutations in mRNA sequences …


In Situ Gel Of Triamcinolone Acetonide-Loaded Solid Lipid Nanoparticles For Improved Topical Ocular Delivery: Tear Kinetics And Ocular Disposition Studies, Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Sai Prachetan Balguri, Bharathi Avula, Monica M. Jablonski, Soumyajit Majumdar Dec 2018

In Situ Gel Of Triamcinolone Acetonide-Loaded Solid Lipid Nanoparticles For Improved Topical Ocular Delivery: Tear Kinetics And Ocular Disposition Studies, Akshaya Tatke, Narendar Dudhipala, Karthik Yadav Janga, Sai Prachetan Balguri, Bharathi Avula, Monica M. Jablonski, Soumyajit Majumdar

Faculty and Student Publications (Open Access)

Triamcinolone acetonide (TA), an intermediate acting corticosteroid, is used in the treatment of posterior ocular diseases, such as inflammation, posterior uveitis, and diabetic macular edema. The objective of this investigation was to prepare TA-loaded solid lipid nanoparticles (TA-SLNs) and in situ gel (TA-SLN-IG) formulations for delivery into the deeper ocular tissues through the topical route. TA-SLNs were prepared by hot homogenization and ultrasonication method using glyceryl monostearate and Compritol® 888ATO as solid lipids and Tween®80 and Pluronic® F-68 as surfactants. TA-SLNs were optimized and converted to TA-SLN-IG by the inclusion of gellan gum and evaluated for their rheological properties. In …


Effects Of Endophyte-Infected Tall Fescue Seed And Red Clover Isoflavones On Rumen Microbial Populations And Physiological Parameters Of Beef Cattle, Emily A. Melchior, Jason K. Smith, Liesel G. Schneider, Travis Mulliniks, Gary E. Bates, Michael D. Flythe, James L. Klotz, Huihua Ji, Jack P. Goodman, Amanda R. Lee, J. Marc Caldwell, Phillip R. Myer Dec 2018

Effects Of Endophyte-Infected Tall Fescue Seed And Red Clover Isoflavones On Rumen Microbial Populations And Physiological Parameters Of Beef Cattle, Emily A. Melchior, Jason K. Smith, Liesel G. Schneider, Travis Mulliniks, Gary E. Bates, Michael D. Flythe, James L. Klotz, Huihua Ji, Jack P. Goodman, Amanda R. Lee, J. Marc Caldwell, Phillip R. Myer

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Lolium arundinaceum [(Darbyshire) tall fescue] toxicosis is responsible for substantial beef production losses in the United States, due to its negative effects on reproduction, growth, and feed efficiency. These effects are consequences of toxic alkaloids within tall fescue. Interseeding legumes, such as Trifolium pratense (red clover), into pastures has been shown to mitigate a portion of these effects. Clovers contain isoflavones, which may play a role in tall fescue toxicosis mitigation. The present study utilized 36 Angus steers to determine the effects of daily supplementation with a red clover- isolated isoflavone feed additive on physiological symptoms of tall fescue toxicosis …


Pulmonary Toxicity And Lung Tumorigenic Potential Of Surrogate Metal Oxides In Gas Metal Arc Welding–Stainless Steel Fume: Iron As A Primary Mediator Versus Chromium And Nickel, Lauryn M. Falcone, Aaron Erdely, Rebecca Salmen, Michael Keane, Lori Battelli, Vamsi Kodali, Aleksandr B. Stefaniak, Michael L. Kashon, James M. Antonini, Patti C. Zeidler-Erdely Dec 2018

Pulmonary Toxicity And Lung Tumorigenic Potential Of Surrogate Metal Oxides In Gas Metal Arc Welding–Stainless Steel Fume: Iron As A Primary Mediator Versus Chromium And Nickel, Lauryn M. Falcone, Aaron Erdely, Rebecca Salmen, Michael Keane, Lori Battelli, Vamsi Kodali, Aleksandr B. Stefaniak, Michael L. Kashon, James M. Antonini, Patti C. Zeidler-Erdely

Faculty & Staff Scholarship

In 2017, the International Agency for Research on Cancer classified welding fumes as “car- cinogenic to humans” (Group 1). Both mild steel (MS) welding, where fumes lack carcino- genic chromium and nickel, and stainless steel (SS) increase lung cancer risk in welders; therefore, further research to better understand the toxicity of the individual metals is needed. The objectives were to (1) compare the pulmonary toxicity of chromium (as Cr(III) oxide [Cr2O3] and Cr (VI) calcium chromate [CaCrO4]), nickel [II] oxide (NiO), iron [III] oxide (Fe2O3), and gas metal arc welding-SS (GMAW-SS) fume; and (2) determine if these metal oxides can …


Using Theater To Promote The Development Of Literacy And Reading Comprehension, Alexandra B. Harrington Dec 2018

Using Theater To Promote The Development Of Literacy And Reading Comprehension, Alexandra B. Harrington

Graduate Student Independent Studies

This paper explores using theater to develop literacy and deepen the comprehension of literature for elementary aged students. Using Louise Rosenblatt’s (1994) framework for aesthetic reading, it discusses the ways in which theater facilitates the reader’s selection, interpretations, and analysis of plots, settings, and characters. This transactional relationship between the reader and text is explored with particular focus on the multi-sensory experiences in theater which support students’ perspective taking. In particular, it explores the visual and kinesthetic opportunities that theater offers to differentiate instruction for diverse learners. In addition, when children engage with theater as participants, they practice expression, building …


Effects Of Soil Nitrogen On Diploid Advantage In Fireweed, Chamerion Angustifolium (Onagraceae), Alex L. Bales, Erika Hersch-Green Dec 2018

Effects Of Soil Nitrogen On Diploid Advantage In Fireweed, Chamerion Angustifolium (Onagraceae), Alex L. Bales, Erika Hersch-Green

Department of Biological Sciences Publications

In many ecosystems, plant growth and reproduction are nitrogen limited. Current and predicted increases of global reactive nitrogen could alter the ecological and evolutionary trajectories of plant populations. Nitrogen is a major component of nucleic acids and cell structures, and it has been predicted that organisms with larger genomes should require more nitrogen for growth and reproduction and be more negatively affected by nitrogen scarcities than organisms with smaller genomes. In a greenhouse experiment, we tested this hypothesis by examining whether the amount of soil nitrogen supplied differentially influenced the performance (fitness, growth, and resource allocation strategies) of diploid and …


The Impact Of Hurricane Matthew On School Attendance: An Analysis From Rural Haiti, Amanda C. Cook, Donovan Beachy Dec 2018

The Impact Of Hurricane Matthew On School Attendance: An Analysis From Rural Haiti, Amanda C. Cook, Donovan Beachy

Economics Faculty Publications

This study identifies the impact of Hurricane Matthew on school attendance in an agricultural community in rural Haiti. We conducted a survey of parents whose children attended a rural school prior to Hurricane Matthew to determine the mechanism by which hurricanes impact school attendance. We determined the marginal effect of family size and school enrollment using a probit model. Parents identified two primary causes for their children leaving school: a loss of income—through crop damage and livestock deaths—and requiring the children’s labor on the family farm. In our sample 96 children, 46% of the children enrolled in school, stopped attending …


Uab Expands To Meet Demand For Japanese Language Instruction, Staff Dec 2018

Uab Expands To Meet Demand For Japanese Language Instruction, Staff

Browse All News

No abstract provided.


Phenotypic And Transcriptomic Characterization Of Colonial Phase Variation In The Cholera Pathogen Reveals A Novel Smooth Biofilm-Defective Form, Bliss Nicole Lambert Dec 2018

Phenotypic And Transcriptomic Characterization Of Colonial Phase Variation In The Cholera Pathogen Reveals A Novel Smooth Biofilm-Defective Form, Bliss Nicole Lambert

LSU Doctoral Dissertations

Biofilm formation, through the production of Vibrio polysaccharide (VPS), greatly enhances the environmental fitness and pathogenic success of Vibrio cholerae. As a result of phase variation, V. cholerae can switch from a smooth form to rugose, whose cells produce excess VPS, resulting in highly structured biofilms and greater resistance to stress. To further characterize the reversible process of phase variation, we isolated three colonial lineages. Each lineage began with a smooth parent, N16961, and contained a rugose variant derived from the parent, N16961R, as well as a smooth revertant of the rugose, N16961SD. We found clear phenotypic and transcriptomic …


Vibrational Analysis Of A Rate-Slowing Conformational Kinetic Isotope Effect, O. Maduka Ogba, Zichen Liu, Daniel J. O'Leary Dec 2018

Vibrational Analysis Of A Rate-Slowing Conformational Kinetic Isotope Effect, O. Maduka Ogba, Zichen Liu, Daniel J. O'Leary

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

An enthalpy-entropy approach to analyzing a rate-slowing conformational kinetic isotope effect (CKIE) in a deuterated doubly-bridged biaryl system is described. The computed isotope effect (kH/kD = 1.075, 368 K) agrees well with the measured value (kH/kD = 1.06, 368 K). The rateslowing (normal isotope effect) nature of the computed CKIE is shown to originate from a vibrational entropy contribution defined by the twenty lowest frequency normal modes in the ground state and transition state structures. This normal entropy contribution is offset by an inverse vibrational enthalpy contribution, which also arises from the twenty lowest frequency normal modes. Zero point vibrational …


Integral Feedback Control Is At The Core Of Task Allocation And Resilience Of Insect Societies, Thomas Schmickl, Istvan Karsai Dec 2018

Integral Feedback Control Is At The Core Of Task Allocation And Resilience Of Insect Societies, Thomas Schmickl, Istvan Karsai

ETSU Faculty Works

Homeostatic self-regulation is a fundamental aspect of open dissipative systems. Integral feedback has been found to be important for homeostatic control on both the cellular and molecular levels of biological organization and in engineered systems. Analyzing the task allocation mechanisms of three insect societies, we identified a model of integral control residing at colony level. We characterized a general functional core mechanism, called the “common stomach,” where a crucial shared substance for colony function self-regulates its own quantity via reallocating the colony’s workforce, which collects and uses this substance. The central component in a redundant feedback network is the saturation …


High Affinity Binding Of H3k14ac Through Collaboration Of Bromodomains 2, 4 And 5 Is Critical For The Molecular And Tumor Suppressor Functions Of Pbrm1., Lili Liao, Nilda L. Alicea-Velázquez, Lauren Langbein, Xiaohua Niu, Weijia Cai, Eun-Ah Cho, Meiling Zhang, Celeste B. Greer, Qin Yan, Michael S. Cosgrove, Haifeng Yang Dec 2018

High Affinity Binding Of H3k14ac Through Collaboration Of Bromodomains 2, 4 And 5 Is Critical For The Molecular And Tumor Suppressor Functions Of Pbrm1., Lili Liao, Nilda L. Alicea-Velázquez, Lauren Langbein, Xiaohua Niu, Weijia Cai, Eun-Ah Cho, Meiling Zhang, Celeste B. Greer, Qin Yan, Michael S. Cosgrove, Haifeng Yang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Polybromo-1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl-lysine residues. While BD2 has been found to bind acetylated histone H3 lysine 14 (H3K14ac), it is not known whether other BDs collaborate with BD2 to generate strong binding to H3K14ac, and the importance of H3K14ac recognition for the molecular and tumor suppressor function of PBRM1 is also unknown. We discovered that full-length PBRM1, but not its individual BDs, strongly binds H3K14ac. BDs 2, 4, and 5 were found to collaborate to facilitate strong binding to H3K14ac. Quantitative …


Mutants Of Cocaine Esterase, Donald Landry, Chang-Guo Zhan Dec 2018

Mutants Of Cocaine Esterase, Donald Landry, Chang-Guo Zhan

Pharmaceutical Sciences Faculty Patents

Provided are mutant cocaine esterase polypeptides and PEGylated formulations thereof.


The Role Of The World Food Security, A.B. Khodjaeva Dec 2018

The Role Of The World Food Security, A.B. Khodjaeva

Review of law sciences

This article outlines the general recommendation, key features of FAO and the World Food Program, compliance with specific international standards, as well as the importance of food security and analysis of Uzbekistan's measures and their further improvement. The Food and Agriculture Organization of the United Nations (FAO), as a specialized UN agency for nutrition, food and agriculture, has been striving for more than 60 years to expand its main goals: to improve the quality of food and the standard of living of people all over the world; ensuring the growth of efficiency of production and distribution of all food and …


Alegal: Biopolitics And The Unintelligibility Of Okinawan Life, Annmaria M. Shimabuku Dec 2018

Alegal: Biopolitics And The Unintelligibility Of Okinawan Life, Annmaria M. Shimabuku

Sociology

Okinawan life, at the crossroads of American militarism and Japanese capitalism, embodies a fundamental contradiction to the myth of the monoethnic state. Suspended in a state of exception, Okinawa has never been an official colony of the Japanese empire or the United States, nor has it ever been treated as an equal part of Japan. As a result, Okinawans live amid one of the densest concentrations of U.S. military bases in the world. By bringing Foucauldian biopolitics into conversation with Japanese Marxian theory, Alegal uncovers Japan’s determination to protect its middle class from the racialized sexual contact around its mainland …


Targeted Therapies For Advanced Non-Small Cell Lung Cancer, Xiaojuan Ai, Xialing Guo, Jun Wang, Andreea L Stancu, Patrick M N Joslin, Dianzheng Zhang, Shudong Zhu Dec 2018

Targeted Therapies For Advanced Non-Small Cell Lung Cancer, Xiaojuan Ai, Xialing Guo, Jun Wang, Andreea L Stancu, Patrick M N Joslin, Dianzheng Zhang, Shudong Zhu

PCOM Scholarly Works

Lung cancer is a serious health problem and the leading cause of cancer death worldwide, due to its high incidence and mortality. 85% of lung cancers are represented by the non-small cell lung cancer (NSCLC). Traditional chemotherapy has been the main treatment option in NSCLC. However, it is often associated with limited efficacy and overall poor patient survival. In recent years, molecular targeting has achieved great progress in therapeutic treatment of cancer and plays a crucial role in the current clinical treatment of NSCLC, due to enhanced efficacy on cancer tissues and reduced toxicity for normal tissues. In this review, …