Digital Commons Network^™

The Indiana Statesman, October 9, 2018, Indiana State University

Student Newspaper

TIE DYE: Make your Homecoming colorful; Johns Hopkins Univ to name building for Henrietta Lacks; Bless the Mic celebrates Homecoming; Kavanaugh fight ignites passions for both parties

Viable Mice With Extensive Gene Humanization (25-Kbp) Created Using Embryonic Stem Cell/Blastocyst And Crispr/Zygote Injection Approaches., Tiffany Leidy-Davis, Kai Cheng, Leslie Goodwin, Judith L Morgan, Wen Chun Juan, Xavier Roca, S Tiong Ong, David E. Bergstrom

Faculty Research 2018

Here, we describe an expansion of the typical DNA size limitations associated with CRISPR knock-in technology, more specifically, the physical extent to which mouse genomic DNA can be replaced with donor (in this case, human) DNA at an orthologous locus by zygotic injection. Driving our efforts was the desire to create a whole animal model that would replace 17 kilobase pairs (kbp) of the mouse Bcl2l11 gene with the corresponding 25-kbp segment of human BCL2L11, including a conditionally removable segment (2.9-kbp) of intron 2, a cryptic human exon immediately 3' of this, and a native human exon some 20 kbp …

Approved Courses, October 9, 2018, Individual Course Committee

Individual Course Committee (ICC)

No abstract provided.

College Voice Vol. 42 No. 2 [October 9, 2018], Connecticut College

2018-2019

No abstract provided.

Use Of Virtual Games For Interactive Learning In A Pharmacy Curriculum, Jerika Lam, Mary Gutierrez, Jeff A. Goad, Larisa Odessky, Jason Bock

Pharmacy Faculty Articles and Research

Background and purpose: To evaluate student pharmacists’ attitudes and satisfaction toward playing educational virtual games in the classroom.

Educational activity and setting: The study setting was playing virtual games in the classroom setting. First year student pharmacists participated in two Mimycx quests in the Healthcare Communication and the Psychiatry/Neurology courses. Students were randomly assigned into teams and worked together to complete the assigned quest games. Completion of the pre- and post-quest questionnaires via Qualtrics was voluntary.

Findings: A total of 79 student pharmacists played the Mimycx quests. Only 66 students completed both pre- and post-quest questionnaires. Students …

The Current Volume 29 : Issue 9, Nova Southeastern University

Student Newspapers

No abstract provided.

Vancomycin Delays Clindamycin-Induced Fatality In The Hamster Model Of Clostridioides [Clostridium] Difficile Infection, Amelia E. Fox-King, Chrisabelle Mefferd, Jacqueline R. Phan, Nancy O. Nou, Ernesto Abel-Santos, Brian P. Hedlund

LSAMP Poster Presentations

Antibiotics can leave the host gut microbiome susceptible to Clostridioides [Clostridium] difficile colonization and lethal toxin production. For instance, clindamycin-induced susceptibility to C. difficile infection (CDI) results in rapid fatality in hamster models, yet vancomycin has been shown to offer increased survival in hamsters challenged with C. difficile. We aim to develop an antibiotic treatment that will facilitate CDI susceptibility without prompt fatality in hamster models. An antibiotic regimen starting with a continuous vancomycin treatment along with a single clindamycin dosage is thought to reduce the major disruption in the indigenous gut microbiome and prevent clindamycin-induced death. …

Film Festival Offers Screenings, Educational Opportunities, Katherine Stewart

University of Mississippi News

New date paves way for collaboration with Oxford Film Festival

The Role Of Inflammation And Immune Cells In Blood Flow Restriction Training Adaptation: A Review, Fabrício Eduardo Rossi, Marcelo Conrado De Freitas, Nelo Eidy Zanchi, Fábio Santos Lira, Jason M. Cholewa

Kinesiology

Blood flow restriction (BFR) combined with low-intensity strength training has been shown to increase skeletal muscle mass and strength in a variety of populations. BFR results in a robust metabolic stress which is hypothesized to induce muscle growth via increased recruitment of fast-twitch muscle fibers, a greater endocrine response, and/or enhancing the cellular swelling contribution to the hypertrophic process. Following exercise, neutrophils are the first immune cells to initiate the tissue remodeling process via several mechanisms including an increased production of cytokines and recruitment of monocytes/macrophages, which facilitate the phagocytosis of foreign particles, the differentiation of myoblasts, and the formation …

October 9, 2018, The Dakota Student

The Dakota Student

No abstract provided.

How Wide Is Wide Enough?: Science, Values, And Law In Riparian Habitat Conservation, George Wilhere, Timothy Quinn

Natural Resources Journal

Difficult environmental policy issues often elicit fervent declarations to “follow the science.” Such declarations ignore the essential role of values in policy making. The main purpose of this article is to clarify the relationships among science, values, and law in environmental policy. An important policy issue in wildlife conservation, is determining “how much is enough?” That is, what is the smallest amount of habitat or minimum population size that is adequate for the long-term survival of wildlife populations? This paper presents three case studies in which policy makers decided how much was enough for protecting freshwater salmonid habitats. The case …

Mitochondrial Fusion And Bid-Mediated Mitochondrial Apoptosis Are Perturbed By Alcohol With Distinct Dependence On Its Metabolism, Shamim Naghdi, William S. Slovinsky, Muniswamy Madesh, Emanual Rubin, György Hajnóczky

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell’s fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial permeability transition pore opening to promote cell death. EtOH-induced tissue injury is primarily attributed to its toxic metabolic products but alcoholism also impairs tissues that poorly metabolize EtOH. We embarked on studies to determine the respective roles of EtOH and its metabolites in mitochondrial fusion and tBid-induced mitochondrial apoptosis. We used HepG2 cells that do not metabolize EtOH and its engineered clone that expresses EtOH-metabolizing Cytochrome P450 E2 and alcohol …

Icc Agenda, October 9, 2018, Individual Course Committee

Individual Course Committee (ICC)

No abstract provided.

Hyperphosphorylation Of Tau Associates With Changes In Its Function Beyond Microtubule Stability, Alejandra D. Alonso, Leah S. Cohen, Christopher Corbo, Viktoriya Morozova, Abdeslem Elldrissi, Greg R. Phillips, Frida E. Kleiman

Publications and Research

Tau is a neuronal microtubule associated protein whose main biological functions are to promote microtubule self-assembly by tubulin and to stabilize those already formed. Tau also plays an important role as an axonal microtubule protein. Tau is an amazing protein that plays a key role in cognitive processes, however, deposits of abnormal forms of tau are associated with several neurodegenerative diseases, including Alzheimer disease (AD), the most prevalent, and Chronic Traumatic Encephalopathy (CTE) and Traumatic Brain Injury (TBI), the most recently associated to abnormal tau. Tau post-translational modifications (PTMs) are responsible for its gain of toxic function. Alonso et al. …

Volume 116, Number 4 - Tuesday, October 9, 2018, Saint Mary's College Of California

The Collegian

No abstract provided.

College Of Education News, College Of Education, Georgia Southern University

College of Education: News & Publications (2003-2023)

• College of Education alum receives national recognition for administration role

• STEMFest returns with a bang, slime and even an alpaca

Aplodinotus Grunniens - Freshwater Drum, Roger W. Barbour

Roger W. Barbour Slide Collection

Aplodinotus grunniens - Freshwater drum

A. Bifascia - Florida Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

A. bifascia - Florida Sand Darter

Aplodinotus Grunniens - Freshwater Drum, Roger W. Barbour

Roger W. Barbour Slide Collection

Aplodinotus grunniens - Freshwater drum

Ammocrypta Vivax - Scaly Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Ammocrypta vivax - Scaly Sand Darter

Ammocrypta Pellucida - Eastern Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Ammocrypta pellucida - Eastern Sand Darter

A. Meridiana - Southern Sand Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

A. meridiana - Southern Sand Darter

Chologaster Cornuta - Swampfish, Roger W. Barbour

Roger W. Barbour Slide Collection

Chologaster cornuta - Swampfish

Carpiodes Carpio - River Carpsucker, Roger W. Barbour

Roger W. Barbour Slide Collection

Carpiodes carpio - River Carpsucker

Cichlasoma Cyanoguttatum - Rio Grande Cichlid, Roger W. Barbour

Roger W. Barbour Slide Collection

Cichlasoma cyanoguttatum - Rio Grande Cichlid

Campostoma C. Anomalum - Central Stoneroller, Roger W. Barbour

Roger W. Barbour Slide Collection

Campostoma c. anomalum - Central Stoneroller

Clinostomus Funduloides - Rosyside Dace, Roger W. Barbour

Roger W. Barbour Slide Collection

Clinostomus funduloides - Rosyside Dace

Chologaster Agassizi - Swampfish, Roger W. Barbour

Roger W. Barbour Slide Collection

Chologaster agassizi - Swampfish

Cottus Carolinae - Banded Sculpin, Roger W. Barbour

Roger W. Barbour Slide Collection

Cottus carolinae - Banded sculpin

Centrarchus Macropterus Flier, Roger W. Barbour

Roger W. Barbour Slide Collection

Centrarchus macropterus - Flier