Digital Commons Network^™

Functional Assessment Of 2,177 U.S. And International Drugs Identifies The Quinoline Nitroxoline As A Potent Amoebicidal Agent Against The Pathogen Balamuthia Mandrillaris, Matthew T. Laurie, Corin V. White, Hanna Retallack, Wesley Wu, Matthew S. Moser, Judy A. Sakanari, Kenny Ang, Christopher Wilson, Michelle R. Arkin, Joseph L. Derisi

UROC Staff Publications and Presentations

Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B. mandrillaris—a proliferative trophozoite form and a nonproliferative cyst form, which is highly resistant to harsh physical and chemical conditions—have been isolated from environmental samples worldwide and are both observed in infected tissue. Patients suffering from GAE are typically treated with aggressive and prolonged multidrug regimens that often include the antimicrobial agents miltefosine and pentamidine isethionate. However, survival rates remain low, and studies evaluating the susceptibility of B. mandrillaris to …

Perceptions, Knowledge And Experiences Among Police Officers: Traffic Stops, Vehicle Searches And K-9 Involvement, Daniel Ozment

Master of Science in Criminal Justice Theses & (Pre-2016) Policy Research Projects

This survey study explores the perceptions, knowledge and experiences of police “line” officers concerning Fourth Amendment search and seizure norms and applications during traffic stops and vehicles searches, in particular police use of canine units following the landmark United States Supreme Court decision of Rodriguez v. United States. In particular, the study examines issues surrounding the length and scope of a traffic stop by police, including stops with canine involvement. Finally, the study includes an analysis of how federal courts of appeal and Georgia courts have interpreted the Rodriguez decision.

Landscape Genetics Reveal Broad And Fine‐Scale Population Structure Due To Landscape Features And Climate History In The Northern Leopard Frog (Rana Pipiens) In North Dakota, Justin M. Waraniak, Justin D. L. Fisher, Kevin Purcell, David M. Mushet, Craig A. Stockwell

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current population genetic structure. This study used 11 microsatellite loci to genotype 1,230 northern leopard frogs (Rana pipiens) from 41 wetlands (30 samples/wetland) across North Dakota. Genetic structure of the sampled frogs was evaluated using Bayesian and multivariate clustering methods. All analyses produced concordant results, identifying a major east–west split between two R. pipiens population clusters separated by the Missouri River. Substructuring within the two major identified …

Landscape Genetics Reveal Broad And Fine‐Scale Population Structure Due To Landscape Features And Climate History In The Northern Leopard Frog (Rana Pipiens) In North Dakota, Justin M. Waraniak, Justin D.L. Fisher, Kevin Purcell, David M. Mushet, Craig A. Stockwell

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current population genetic structure. This study used 11 microsatellite loci to genotype 1,230 northern leopard frogs (Rana pipiens) from 41 wetlands (30 samples/wetland) across North Dakota. Genetic structure of the sampled frogs was evaluated using Bayesian and multivariate clustering methods. All analyses produced concordant results, identifying a major east–west split between two R. pipiens population clusters separated by the Missouri River. Substructuring within the two major identified …

Invasion Of The P Elements: Tolerance Is Not Futile, Colin D. Meiklejohn, Justin P. Blumenstiel

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Organisms are locked in an eternal struggle with parasitic DNA sequences that live inside their genomes and wreak havoc on their host’s chromosomes as they spread through populations. To combat these parasites, host species have evolved elaborate mechanisms of resistance that suppress their activity. A new study in Drosophila indicates that, prior to the acquisition of resistance, individuals can vary in their ability to tolerate the activity of these genomic parasites, ignoring or repairing the damage they induce. This tolerance results from variation at genes involved in germline development and DNA damage checkpoints and suggests that these highly conserved cellular …

Bats Of St. Vincent, Lesser Antilles, Gary G. Kwiecinski, Scott C. Pedersen, Hugh H. Genoways, Peter A. Larsen, Roxanne J. Larsen, Justin D. Hoffman, Fitzroy Springer, Carleton J. Phillips, Robert J. Baker

University of Nebraska State Museum: Mammalogy Papers

The chiropteran fauna of the island of Saint Vincent, represented by 12 species, is among the most complex in the Lesser Antilles, being represented by four families including Noctilionidae (1 species), Mormoopidae (1), Phyllostomidae (8), and Molossidae (2). This fauna includes four trophic guilds as represented by Noctilio leporinus (piscivore/insectivore); Glossophaga longirostris and Monophyllus plethodon (nectarivore/pollenivore); Artibeus lituratus, A. schwartzi, Brachyphylla cavernarum, Ardops nichollsi, and Sturnira paulsoni (frugivore); and Pteronotus fuscus, Micronycteris buriri, Molossus molossus, and Tadarida brasiliensis (insectivore). One species—Micronycteris buriri—and two subspecies—Sturnira paulsoni paulsoni and Ardops nichollsi vincentensis …

Volume 116, Number 6 - Tuesday, October 30, 2018, Saint Mary's College Of California

The Collegian

No abstract provided.

Erosion Of Coastal Archaeological Sites On Santa Rosa Island, California, Christopher S. Jazwa, Kerri N. Johnson

Western North American Naturalist

The damage and loss of coastal archaeological sites from shoreline transgression and other near-coastal processes is common around the world. It negatively impacts our ability to address important research questions including those about the colonization of the New World, which likely occurred along the Pacific Coast. Differences in geomorphic context, annual weather patterns, topography, vegetation, bedrock, and land-use history lead to distinct localized patterns of erosion even within small geographic regions. We assessed near-coastal erosion on Santa Rosa Island, California, by monitoring annual change at 16 controlled points on 11 archaeological sites from 2013 to 2017 and by comparing it …

California Island Rediscovery: Building An Archive To Improve Conservation Today And Equip The Historical Ecologist Of Tomorrow, Scott A. Morrison, T. Scott Sillett, W. Chris Funk, Cameron K. Ghalambor, Torben C. Rick

Western North American Naturalist

An understanding of how past conditions have shaped present-day ecological patterns and trends is critical to science-based conservation management. Unfortunately, the records, specimens, and objects historical ecologists need to help generate that understanding are often lacking. And because of a general underinvestment by society in systematic collection and museum curation, future historical ecologists may be similarly limited in their ability to investigate conditions regarding our present day. Given the importance of historical data and materials in contemporary conservation decision-making, we suggest it is incumbent upon resource managers and scientists to ask whether additional research efforts are needed to document past …

Biochemical Study Of A Chymotrypsin-Like Serine Protease, Aachymo, From The Female Aedes Aegypti Mosquito, Olive Escalicas Burata

Master's Theses

The Aedes aegypti female mosquito is a dominant vector of four bloodborne viruses: dengue, chikungunya, yellow fever, and Zika. Defenses against viral infection are reliant on human competence to limit interactions with the vector or through abatement using

methods that are either too expensive or ecologically invasive upon other species. An alternative vector control approach focuses specifically on blood meal protein digestion, which is a required process to fuel the gonotrophic cycle. Reduction of eggs laid can be

observed by inhibiting midgut serine proteases that are afterward released in the midgut in the presence of a blood meal. Trypsin-like serine …

Associative Memory Performance Following Periods Of Wakeful Rest And Technological Distraction, Chalise Carlson

Master's Theses

We often spend breaks in our day by engaging with technological devices. However, literature across several species indicates that resting quietly without engaging in other activities, termed wakeful rest, can be beneficial to memory consolidation, a period following encoding which serves to stabilize memories. Prior research demonstrates that wakeful rest benefits memory for single items. However, the effects of wakeful rest on associative memory, (i.e. memory for associations between stimuli), remain unclear. To elucidate the effects of wakeful rest on associative memory, a study was designed to examine differences in associative memory performance following periods of wakeful rest and game …

Diets And Stable Isotope Signatures Of Yellowtail Rockfish (Sebastes Flavidus) In Central California, Jennifer Chiu

Master's Theses

Studies of fish diets can improve the understanding of trophic distributions and the predatory role of a species in an ecosystem. Identifying the spatial and temporal variability in the diets of fishes can provide useful information for stock assessments and management. Yellowtail Rockfish (Sebastes flavidus) are a commercially and recreationally important fishery species, and abundant along the central California coast, yet the most recent studies of diets occurred over 20 years ago in Oregon and Washington. To provide current information from California, I examined the food habits of Yellowtail Rockfish collected near Cordell Bank, the Farallon Islands, and Half Moon …

Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements For Nad+ Synthesis, Laura Palzer, Jessica J. Bader, Frances Angel, Megan Witzel, Sydney Blaser, Alexis Mcneil, Miles K. Wandersee, N. Adrian Leu, Christopher J. Lengner, Clara E. Cho, Kevin D. Welch, James B. Kirkland, Ralph G. Meyer, Mirella L. Meyer-Ficca

Animal, Dairy, and Veterinary Science Faculty Publications

NAD⁺ is essential for redox reactions in energy metabolism and necessary for DNA repair and epigenetic modification. Humans require sufficient amounts of dietary niacin (nicotinic acid, nicotinamide, and nicotinamide riboside) for adequate NAD⁺ synthesis. In contrast, mice easily generate sufficient NAD⁺ solely from tryptophan through the kynurenine pathway. We show that transgenic mice with inducible expression of human alpha-amino-beta-carboxy-muconate-semialdehyde decarboxylase (ACMSD) become niacin dependent similar to humans when ACMSD expression is high. On niacin-free diets, these acquired niacin dependency (ANDY) mice developed reversible, mild-to-severe NAD⁺ deficiency, depending on the nutrient composition of the diet. NAD deficiency …

The Minimum Inhibitory Concentration (Mic) Assay With Escherichia Coli: An Early Tier In The Environmental Hazard Assessment Of Nanomaterials?, J Vassallo, A Besinis, R Boden, Rd Handy

School of Engineering, Computing and Mathematics

No abstract provided.

Mapping The Terrain: An Indonesian Business Perspective Of The Asean Economic Community, Marko S. Hermawan, Lena Choong

The South East Asian Journal of Management

Research Aims - This paper focuses on the institutions that the ASEAN Economic Community (AEC) project will affect. By employing institutional logics theory, this study scrutinizes academics and business practitioners as institutions and the cultural context embedded within them. Methodology - A mixed method of newspaper data analysis and semi-structured interviews was used to obtain comprehensive data from both sources. Research findings - The findings suggest a definite orientation gap between business practitioners, associations, and academics—the three groups have less information and contributions compared with the government and association influences. This study concludes that more participation is needed from these …

Lasiurus Seminolus - Seminole Bat, Roger W. Barbour

Roger W. Barbour Slide Collection

Lasiurus seminolus - Seminole Bat

Leptonycteris Nivalis - Big Long-Nosed Bat, Roger W. Barbour

Roger W. Barbour Slide Collection

Leptonycteris nivalis - Big Long-nosed Bat

Macrotus Waterhousii Californicus, Roger W. Barbour

Roger W. Barbour Slide Collection

Macrotus waterhousii californicus

Myotis Auriculus - Southwestern Myotis, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis auriculus - Southwestern Myotis

Mormoops Megalophylla, Roger W. Barbour

Roger W. Barbour Slide Collection

Mormoops megalophylla

Myotis Californicus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis californicus

Myotis Lucifugus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis lucifugus

Myotis Austroriparius - Southeastern Myotis, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis austroriparius - Southeastern Myotis

Myotis Californicus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis californicus

Myotis Fortidens, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis fortidens

Myotis Keenii, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis keenii

Myotis Keenii, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis keenii

Myotis Lucifugus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis lucifugus

Myotis Lucifugus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis lucifugus

Myotis Occultus, Roger W. Barbour

Roger W. Barbour Slide Collection

Myotis occultus