Digital Commons Network^™

Multistate Infestation With The Exotic Disease-Vector Tick Haemaphysalis Longicornis - United States, August 2017-September 2018, C. B. Beard, James Occi, Denise L. Bonilla, Andrea M. Egizi, Dina M. Fonseca, Gary P. Wormser, William Halperin

NYMC Faculty Publications

Haemaphysalis longicornis is a tick indigenous to eastern Asia and an important vector of human and animal disease agents, resulting in such outcomes as human hemorrhagic fever and reduction of production in dairy cattle by 25%. H. longicornis was discovered on a sheep in New Jersey in August 2017 (1). This was the first detection in the United States outside of quarantine. In the spring of 2018, the tick was again detected at the index site, and later, in other counties in New Jersey, in seven other states in the eastern United States, and in Arkansas. The hosts included six …

Why Hannibal Lost The Second Punic War, Ho Yee Lam

Armstrong Undergraduate Journal of History

In the Second Punic War, Hannibal planned to feed his army with the Roman grain supply, turn Italian cities against Rome, and seek reinforcements from any enemy of Rome. However, although Hannibalic tactics were ingenious in a short-term war, they were unsuitable for a long-term campaign. Unable to conquer mighty Rome, his plans backfired—especially in Spain and eventually in Africa, where Roman victories led to Carthage’s ultimate and total defeat. His ally, geography, turned into his enemy, because the war lasted far longer than he predicted and the Romans were able to use the great distance between Hannibal and his …

Home On The Range: The Impact Of The Cattle Trails On Indian Territory, Paul Roland

Armstrong Undergraduate Journal of History

This paper addresses how the cattle trails affected the Native American tribes in Indian Territory. There has been a plethora of research done on finding the cattle trails, life as a cowboy, and the economics of the cattle trade, but precious little is said about its impact on the Indians, whose land the trails went through. This paper examines the role of cattle in tribes prior to relocation, how the Five Civilized/Eastern Tribes utilized cattle and interacted with early cattle trails, and how the Western Plains Tribes reacted to cattle trails moving westward. The cattle trails provided for a new …

Zinc Enhances Hippocampal Long-Term Potentiation At Ca1 Synapses Through Nr2b Containing Nmda Receptors, John Sullivan, Xiao-Lei Zhang, Arthur P. Sullivan, Linnea R. Vose, Alexander A. Moghadam, Victor A. Fried, Patric K. Stanton

NYMC Faculty Publications

The role of zinc (Zn2+), a modulator of N-methyl-D-aspartate (NMDA) receptors, in regulating long-term synaptic plasticity at hippocampal CA1 synapses is poorly understood. The effects of exogenous application of Zn2+ and of chelation of endogenous Zn2+ were examined on long-term potentiation (LTP) of stimulus-evoked synaptic transmission at Schaffer collateral (SCH) synapses in field CA1 of mouse hippocampal slices using whole-cell patch clamp and field recordings. Low micromolar concentrations of exogenous Zn2+ enhanced the induction of LTP, and this effect required activation of NMDA receptors containing NR2B subunits. Zn2+ elicited a selective increase in NMDA/NR2B fEPSPs, and removal of endogenous Zn2+ …

Prenatal Tobacco And Marijuana Co-Use: Impact On Newborn Neurobehavior., Laura R. Stroud, George D. Papandonatos, Meaghan Mccallum, Tessa Kehoe, Amy L. Salisbury, Marilyn A. Huestis

Institute of Emerging Health Professions Faculty Papers

Tobacco and marijuana are some of the most common prenatal substance exposures worldwide. The social acceptability and political landscape of marijuana and its potency have changed dramatically in the last two decades leading to increased use by pregnant women. Despite evidence for increasing marijuana use and high rates of co-use of tobacco (TOB) and marijuana (MJ) during pregnancy, the impact of prenatal exposure to each substance is typically studied in isolation. We investigated the influence of co-exposure to TOB and MJ on infant neurobehavioral development over the first postnatal month. Participants were 111 mother-infant pairs from a low-income, diverse sample …

Closed Meetings Under Foia Turn Fifty: The Old, The New, And What To Do, Tyler C. Southall

University of Richmond Law Review

No abstract provided.

Effects Of Tumor Metabolic Microenvironment On Regulatory T Cells, Yi-An Wang, Xiao-Ling Li, Yong-Zhen Mo, Chun-Mei Fan, Le Tang, Fang Xiong, Can Guo, Bo Xiang, Ming Zhou, Jian Ma, Xi Huang, Xu Wu, Yong Li, Gui-Yuan Li, Zhao-Yang Zeng, Wei Xiong

Chemistry Faculty Publications

Recent studies have shown that on one hand, tumors need to obtain a sufficient energy supply, and on the other hand they must evade the body’s immune surveillance. Because of their metabolic reprogramming characteristics, tumors can modify the physicochemical properties of the microenvironment, which in turn affects the biological characteristics of the cells infiltrating them. Regulatory T cells (Tregs) are a subset of T cells that regulate immune responses in the body. They exist in large quantities in the tumor microenvironment and exert immunosuppressive effects. The main effect of tumor microenvironment on Tregs is to promote their differentiation, proliferation, secretion …

Ecofeminism And Cultural Ecology: A Framework Of Connections And Intersections For Reading Margret Atwood’S “Habitation”, “The City Planners”, “Morning In The Burned House”, “February”, And “ Night Poem”, Maha M. Munib Abdelmotaleb

English Language and Literature

Cultural ecology and Ecofeminism are two concepts that intersect with each other. Both concepts define and reinforce each other. It could be claimed that, Ecofeminism is one manifestation of cultural ecology since the former tackles issues about feminism’s relationship with nature including nature domination and the duality of nature which find their echoes in cultural ecology as well. The whole idea of the earth’s subjugation and male domination as well as the male/ female duality of nature in general find resonance in feminist resistance to patriarchal domination which develop under the umbrella of Ecofeminism to be part of the struggle …

Chinese New Year, Lily Ward

USU Student Folklore Fieldwork

The Chinese New Year is by far the most important holiday in China. Millions of Factory Workers leave their homes and live in dormitories by the factories they work in and they never see their families except for the Chinese New Year and the Fall Harvest celebration. Factories close, many restaurants and small businesses close and all those who have families go back to their “home towns” and stay for a few weeks. The trains are so jammed full that folks are standing in the aisles. If for any reason trains are delayed, chaos immediately erupts. If the delay is …

Buckwheat Festival, Eliza Jorgensen

USU Student Folklore Fieldwork

Having grown up in Preston County, West Virginia, the Buckwheat Festival was a uh festival that was help the last weekend in September the last Saturday of September every year to celebrate the harvest and to uh display some of the animals that the 4Hers and FFA members would would had had raised during the year. There was also a carnival there there was a – buckwheat is a crop that is grow extensively in Preston County and makes very nice flour or buckwheat flour. One of the traditions at the Buckwheat Festival, it’s in Kingwood, West Virginia is the …

The Type I Interferon Receptor Is Not Required For Protection In The Chlamydia Muridarum And Hsv-2 Murine Super-Infection Model, Jessica A. Slade, Jennifer V. Hall, Jennifer Kintner, Robert V. Schoborg

ETSU Faculty Works

Chlamydia trachomatis/HSV-2 vaginal co-infections are seen clinically, suggesting that these sexually transmitted pathogens may interact. We previously established an intravaginal Chlamydia muridarum/HSV-2 super-infection model and observed that chlamydial pre-infection protects mice from a subsequent lethal HSV-2 challenge. However, the mechanism of protection remains unknown. The type I interferon, IFN-β, binds to the type I interferon receptor (IFNR), elicits a host cellular antiviral response and inhibits HSV replication in vitro and in vivo. Previous studies have demonstrated that C. muridarum infection stimulates genital tract (GT) IFN-β production; therefore, we hypothesized that chlamydial pre-infection protects mice from HSV-2 challenge via the IFN-β/IFNR-induced …

Population Genetics Of The Eastern Subterranean Termite, Reticulitermes Flavipes, In The Southern Appalachian Mountains, Lee Ann Passarella

Honors Theses

As an area rich in biodiversity, the Appalachian Mountains are an ideal place for biological research. The pronounced impacts of Pleistocene climatic cycles on forest distributions over time have shaped the evolutionary history of animals that depend on these habitats, underpinning the research that is presented here. The present study on the eastern subterranean termite, Reticulitermes flavipes, was conducted to better understand the spatial distribution of genetic diversity within and among populations of this species in the context of the aforementioned historical climatic changes in the southern Appalachian Mountain region. I hypothesized that there would be geographically localized, distinct genetic …

“The New Geography,” Material Science, And Narratology’S Space-Time Dichotomy: Notes Toward A Geographical Narratology, Nancy Easterlin

English Faculty Publications

This essay places narratology’s emphasis on space-time within the emergence of the discipline of geography and the rise of a materialist, hard science orientation in US institutions after WWII, ultimately arguing that a nascent geographical narratology should aspire to the broad intellectual scope of geography’s origins. “The new geography,” which emerged in 1887 and focused comprehensively on the relation of humans to the earth’s surface, subsequently contracted and fragmented with the post-war emphasis on material science. Likewise expanding in the rationalist post-war climate, classical narratology emphasized logical categories, especially the space-time dichotomy, divorced from human meanings. Today, cognitive research suggests …

Developing Serious Games In Engineering Education: Innovation At The Nexus Of Food, Energy, And Water Systems, Nathan Rice

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

At a time when food, energy, and water (FEW) are of the utmost concern to the security and health of the world, an initiative has begun to understand the interactions between these systems. The goal of Innovation at the Nexus of Food, Energy, and Water Systems (INFEWS) is to bring together research fields that typically work in their own silos to solve complex problems increasing the resiliency and sustainability of the FEW system. Stemming from this initiative was a project to produce an educational immersive simulation game to teach youth about how their food is produced, systems thinking, and sustainable …

Repair And Adaptation Of Aged Skeletal Muscle To Nonpathological Muscle Damage: The Influence Of Macrophage Polarization, Jacob R. Sorensen

Theses and Dissertations

The age-related loss of skeletal muscle mass and function is accompanied by a decline in regenerative capacity. The processes that facilitate healthy muscle repair are complex, involving several phases of degradation and rebuilding of muscle tissue and the surrounding microenvironment. Specifically, myogenic progenitor cells known as satellite cells are the most influential in repairing damaged muscle tissue. Following injury, satellite cells become activated and migrate, proliferate and fuse with mature skeletal muscle fibers to restore homeostasis to the tissue. However, satellite cells do not act in isolation, a robust inflammatory response is necessary to facilitate successful and rapid healing. Macrophages …

Netlight: Cloud Baked Indirect Illumination, Nathan Andrew Zabriskie

Theses and Dissertations

Indirect lighting drastically increases the realism of rendered scenes but it has traditionally been very expensive to calculate. This has long precluded its use in real-time rendering applications such as video games which have mere milliseconds to respond to user input and produce a final image. As hardware power continues to increase, however, some recently developed algorithms have started to bring real-time indirect lighting closer to reality. Of specific interest to this paper, cloud-based rendering systems add indirect lighting to real-time scenes by splitting the rendering pipeline between a server and one or more connected clients. However, thus far they …

Vision-Based Emergency Landing Of Small Unmanned Aircraft Systems, Parker Chase Lusk

Theses and Dissertations

Emergency landing is a critical safety mechanism for aerial vehicles. Commercial aircraft have triply-redundant systems that greatly increase the probability that the pilot will be able to land the aircraft at a designated airfield in the event of an emergency. In general aviation, the chances of always reaching a designated airfield are lower, but the successful pilot might use landmarks and other visual information to safely land in unprepared locations. For small unmanned aircraft systems (sUAS), triply- or even doubly-redundant systems are unlikely due to size, weight, and power constraints. Additionally, there is a growing demand for beyond visual line …

Proteomics Of Human Liver Membrane Transporters: A Focus On Fetuses And Newborn Infants., Bianca D. Van Groen, Evita Van De Steeg, Miriam G. Mooij, Marola M H Van Lipzig, Barbara A E De Koning, Robert M. Verdijk, Heleen M. Wortelboer, R Gaedigk, Chengpeng Bi, J Steven Leeder, Ron H N Van Schaik, Joost Van Rosmalen, Dick Tibboel, Wouter H. Vaes, Saskia N. De Wildt

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples.

METHODS: Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3, NTCP, OCT1, OATP1B1, OATP1B3, OATP2B1 and ATP1A1 were quantified with LC-MS/MS in isolated crude membrane fractions of snap-frozen post-mortem fetal and pediatric, and surgical adult liver samples. mRNA expression was quantified using RNA sequencing, and genetic variants with TaqMan assays. We explored relationships between protein expression and age …

Spatial Humanities, Katherine M. Jarriel, Megha Anwer, Elizabeth Brite, Matthew Hannah, Amber N. Nickell

Purdue GIS Day

This roundtable introduces spatial humanities researches at Purdue. Projects include "Mapping Victorian women's habitation and violence encounter" by Dr. Megha Anwer; "Animating material agencies with GIS data: an example from the archealogy of the Soviet Union" by Dr. Elizabeth Brite; "Modeling community interaction in Bronze Age Greece" by Dr. Katherine Jarriel; "Mapping 'no place': Eastern and Central Europe's nineteenth and twentieth century phantom, indifferent, and alternative geographies by Amber Nickell.

My Laptop Takes Forever, Now What!, Eric Adams

Purdue GIS Day

ITAP Research Computing's Data Workbench offers researchers access to an interactive computing environment for non-batch big data analysis and simulation. Researchers who outgrow their local computing resources can benefit from the extra computing power that Data Workbench offers without jumping directly into the High-Performance Computing clusters.

In this presentation, we will discuss the details of Data Workbench, file storage options including the Data Depot and how to transfer large files reliably with the Globus research data management service.

Tennessee Farm Bureau News - November 2018, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

Fathers’ Cortisol And Testosterone In The Days Around Infants’ Births Predict Later Paternal Involvement, Patty X. Kuo, Julia M. Braungart-Rieker, Jennifer E. Burke Lefever, Mallika S. Sarma, Molly O'Neill, Lee T. Gettler

Department of Child, Youth, and Family Studies: Faculty Publications

Human paternal behavior is multidimensional, and extant research has yet to delineate how hormone patterns may be related to different dimensions of fathering. Further, although studies vary in their measurement of hormones (i.e., basal or reactivity), it remains unclear whether basal and/or reactivity measures are predictive of different aspects of men’s parenting. We examined whether men’s testosterone and cortisol predicted fathers’ involvement in childcare and play with infants and whether fathers’ testosterone and cortisol changed during fathers’ first interaction with their newborn. Participants were 298 fathers whose partners gave birth in a UNICEF-designated “baby-friendly” hospital, which encourages fathers to hold …

Fatherhood And Psychobiology In The Philippines: Perspectives On Joint Profiles And Longitudinal Changes Of Fathers’ Estradiol And Testosterone, Lee T. Gettler, Patty X. Kuo, Sonny Agustin Bechayda

Department of Child, Youth, and Family Studies: Faculty Publications

Objectives: Research on the psychobiology of partnering and fathering has focused on testosterone (T), oxytocin, and prolactin (PRL) as mechanisms that potentially mediate life history trade-offs related to those roles. Less is known about other hormones that might be responsive to life history transitions and implicated in fathering, such as estradiol (E2). We examined how E2 changed during the transition to marriage and fatherhood, its correlation with fathers’ caregiving, and its joint within-individual production with other hormones (T, PRL). Methods: Data were collected from a total of 913 Filipino men (aged 25.9 years ± 0.3 SD at follow-up) enrolled in …

Hypoxia-Mediated Mitochondria Apoptosis Inhibition Induces Temozolomide Treatment Resistance Through Mir-26a/Bad/Bax Axis., Xin Ge, Min-Hong Pan, Lin Wang, Wei Li, Chengfei Jiang, Jun He, Khaled Abouzid, Ling-Zhi Liu, Zhumei Shi, Bing-Hua Jiang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Glioblastoma multiforme (GBM) is one of the most hypoxic tumors of the central nervous system. Although temozolomide (TMZ) is an effective clinical agent in the GBM therapy, the hypoxic microenvironment remains a major barrier in glioma chemotherapy resistance, and the underlying mechanisms are poorly understood. Here, we find hypoxia can induce the protective response to mitochondrion via HIF-1α-mediated miR-26a upregulation which is associated with TMZ resistance in vitro and in vivo. Further, we demonstrated that HIF-1α/miR-26a axis strengthened the acquisition of TMZ resistance through prevention of Bax and Bad in mitochondria dysfunction in GBM. In addition, miR-26a expression levels negatively …

An Experiment To Study The Gaseous Emissions Of A Gas Turbine Operated With Biodiesel As Fuel, David Lee Rochelle

Theses and Dissertations

A continually growing awareness of the finiteness of fossil fuel availability coupled with an ever better understanding of the negative effects of fossil fuel consumption has motivated a search for fuels that can be used in place of fossil fuels, but which can be derived from sustainable sources such as growable organic matter. While much work has been done to understand these substances and apply them on a larger scale (indeed, biodiesel is commonly included in commercially available diesel fuels at fuel pumps); the unique nature of the operating environment for aviation fuels has complicated the application of these substances …

Real-Time Facial Expression And Speech Emotion Recognition App Development On Mobile Phones Using Cloud Computing, Humaid Saif Saeed Alasli Alshamsi

Theses and Dissertations

Emotion plays a vital role in humans’ daily lives. Understanding emotions and recognizing how to react to others’ feelings are fundamental to engaging in successful social interactions. Emotion recognition through facial expression and speech play a significant role in human communication. This subject is becoming important in academic research as new techniques such as emotion recognition from speech context inspire us to recognize how emotions are related to the content we are uttering. The demand and importance of emotion recognition have highly increased in many applications in recent years, such as video games, human-computer interactions, cognitive computing, and affective computing. …

Multi-Modal Learning Using Deep Neural Networks, Dheeraj Kumar Peri

Theses

Humans have an incredible ability to process and understand information from multiple sources such as images, video, text, and speech. Recent success of deep neural networks has enabled us to develop algorithms which give machines the ability to understand and interpret this information. Convolutional Neural Networks (CNN) have become a standard in extracting rich features from visual stimuli. Recurrent Neural Networks (RNNs) and its variants such as Long Short Term Memory (LSTMs) units have been highly successful in encoding and decoding sequential information like speech and text. Although these networks are highly successful when applied to narrow applications, there is …

The New Hampshire, Vol. 108 [109], No. 10 (Nov. 1, 2018), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 108, but it is the 109th volume in the series.

The Maxillary Incisor Display At Rest: Analysis Of The Underlying Components, Waqar Jeelani, Mubassar Fida, Attiya Shaikh

Section of Dental-Oral Maxillofacial Surgery

Introduction: Maxillary incisal display is one of the most important attributes of smile esthetics. Objective: The aim of this study was to determine the relationship between maxillary incisal display at rest (MIDR) and various soft tissue, hard tissue and dental components. Methods: A cross-sectional study was conducted on 150 subjects (75 males, 75 females) aged 18-30 years. The MIDR was recorded from the pretreatment orthodontic records. The following parameters were assessed on lateral cephalograms: ANB angle, mandibular plane angle, palatal plane angle, lower anterior and total anterior facial heights, upper incisor inclination, upper anterior dentoalveolar height, and upper lip length, …

Triatomines: Trypanosomatids, Bacteria, And Viruses Potential Vectors? [Review], Caroline Barreto Vieira, Yanna Reis Praça, Kaio Luís Da Silva Bentes, Paula Beatriz Santiago, Sofia Marcelino Martins Silva, Gabriel Dos Santos Silva, Flávia Nader Motta, Izabela Marques Dorado Bastos, Jaime Martins De Santana, Carla Nunes De Araújo

Harold W. Manter Laboratory of Parasitology: Library Materials

Triatominae bugs are the vectors of Chagas disease, a major concern to public health especially in Latin America, where vector-borne Chagas disease has undergone resurgence due mainly to diminished triatomine control in many endemic municipalities. Although the majority of Triatominae species occurs in the Americas, species belonging to the genus Linshcosteus occur in India, and species belonging to the Triatoma rubrofasciata complex have been also identified in Africa, the Middle East, South-East Asia, and in the Western Pacific. Not all of Triatominae species have been found to be infected with Trypanosoma cruzi, but the possibility of establishing vector transmission …