Digital Commons Network^™

Antitrust And Inequality: The Problem Of Super-Firms, Shi-Ling Hsu

Scholarly Publications

Increasing concern about economic inequality has coincided with an unsettling ascendancy of some large, technologically integrated “super-firms,” which have grabbed large market shares in multiple markets, and cast doubt upon the future viability of a wide range of businesses, many of which have been important local and regional employers. It is thus unsurprising that these two trends have knocked together in public discourse, and that antitrust law been proposed as one way of helping to remedy economic inequality. This essay notes that antitrust law is generally a poor fit for reducing economic inequality, but one aspect is worthy of note: …

A Multicenter Examination And Strategic Revisions Of The Yale Global Tic Severity Scale, Joseph F. Mcguire, John Piacentini, Eric A. Storch, Tanya K. Murphy, Emily J. Ricketts, Douglas W. Woods, John T. Walkup, Alan L. Peterson, Sabine Wilhelm, Adam B. Lewin, James T. Mccracken, James F. Leckman, Lawrence Scahill

Psychology Faculty Research and Publications

Objective To examine the internal consistency and distribution of the Yale Global Tic Severity Scale (YGTSS) scores to inform modification of the measure.

Methods This cross-sectional study included 617 participants with a tic disorder (516 children and 101 adults), who completed an age-appropriate diagnostic interview and the YGTSS to evaluate tic symptom severity. The distributions of scores on YGTSS dimensions were evaluated for normality and skewness. For dimensions that were skewed across motor and phonic tics, a modified Delphi consensus process was used to revise selected anchor points.

Results Children and adults had similar clinical characteristics, including tic symptom severity. …

Regulation By Database, Nathan Cortez

University of Colorado Law Review

The federal government currently publishes 196,284 searchable databases online, a number of which include information about private parties that is negative or unflattering in some way. Federal agencies increasingly publish adverse data not just to inform the public or promote transparency, but to pursue regulatory ends-to change the underlying behavior being reported. Such "regulation by database" has become a preferred method of regulation in recent years, despite scant attention from policymakers, courts, or scholars on its appropriate uses and safeguards.

This Article evaluates the aspirations and burdens of regulation by database. Based on case studies of six important data sets …

Whose Gig Is It Anyway? Technological Change, Workplace Control And Supervision, And Workers' Rights In The Gig Economy, Alex Kirven

University of Colorado Law Review

Under the current regime of employment and labor laws, coverage is determined on the basis of whether a given worker is an employee as opposed to an independent contractor. These laws contain inadequate definitions of "employee," leaving it up to the court system and administrative agencies to define the term. The current tests that they use fail to capture the realities of the gig economy, a system that purports to promote greater worker freedom through the fragmentation of work assignments into smaller tasks or gigs. The gig economy has offered consumers lower prices and has given workers greater autonomy in …

Climate Change Disinformation, Citizen Competence, And The First Amendment, James Weinstein

University of Colorado Law Review

No abstract provided.

Categorizing Lies, David S. Han

University of Colorado Law Review

No abstract provided.

Developing A Taxonomy Of Lies Under The First Amendment, Alan K. Chen, Justin Marceau

University of Colorado Law Review

No abstract provided.

The Law Of Deception: A Research Agenda, Gregory Klass

University of Colorado Law Review

No abstract provided.

Structure Of The Picornavirus Replication Platform: A Potential Drug Target For Inhibiting Virus Replication, Meghan Suzanne Warden

Chemistry & Biochemistry Theses & Dissertations

Picornaviruses are small, positive-stranded RNA viruses, divided into twelve different genera. Members of the Picornaviridae family cause a wide range of human and animal diseases including the common cold, poliomyelitis, foot and mouth disease, and dilated cardiomyopathy. The picornavirus genome is replicated via a highly conserved mechanism involving a presumed cloverleaf structure located at the 5’ noncoding region of the virus genome. The 5’ cloverleaf consists of three stem loops (B, C, and D) and one stem (A), which interact with a variety of virus and host cell proteins during replication. In this dissertation, human rhinovirus serotype 14 (HRV-14) SLB …

Molecular Candidates For Blocking The Transmission Of Vector-Borne Diseases, Ashish Naresh Vora

Biological Sciences Theses & Dissertations

Vector-borne diseases (VBDs) require urgent attention as they have a high mortality rate, with 700,000 people dying in a year as of 2017. So far, extremely few reliable vaccination strategies and solutions have emerged. Transmission blocking vaccines are one among many solutions available to manage the control of VBDs. These require identification of both vector and pathogen molecules that play important roles in the transmission, dissemination and establishment of VBDs. Our strategy is to characterize these candidates that play important roles in vector-host-pathogen interactions. This manuscript presents two such studies identifying the participation of two arthropod molecules in vector-host-pathogen interactions. …

Adaptive Methods For Point Cloud And Mesh Processing, Zinat Afrose

Computational Modeling & Simulation Engineering Theses & Dissertations

Point clouds and 3D meshes are widely used in numerous applications ranging from games to virtual reality to autonomous vehicles. This dissertation proposes several approaches for noise removal and calibration of noisy point cloud data and 3D mesh sharpening methods. Order statistic filters have been proven to be very successful in image processing and other domains as well. Different variations of order statistics filters originally proposed for image processing are extended to point cloud filtering in this dissertation. A brand-new adaptive vector median is proposed in this dissertation for removing noise and outliers from noisy point cloud data.

The major …

Restaurant Inspection Reports As A Proxy Measure For Occupational Health And Safety: South Asian Restaurant Workers In New York City, Ismail Nabeel, Hasanat Alamgir

NYMC Faculty Publications

No abstract provided.

Does Combined Therapy Of Curcumin And Epigallocatechin Gallate Have A Synergistic Neuroprotective Effect Aainst Spinal Cord Injury?, Jiri Ruzicka, Lucia M. Urdzikova, Anubhav Amin, Sarka Kubinova, Meic Schmidt, Meena Jhanwar-Uniyal, Pavla Jendelova

NYMC Faculty Publications

Systematic inflammatory response after spinal cord injury (SCI) is one of the factors leading to lesion development and a profound degree of functional loss. Anti-inflammatory compounds, such as curcumin and epigallocatechin gallate (EGCG) are known for their neuroprotective effects. In this study, we investigated the effect of combined therapy of curcumin and EGCG in a rat model of acute SCI induced by balloon compression. Immediately after SCI, rats received curcumin, EGCG, curcumin + EGCG or saline [daily intraperitoneal doses (curcumin, 6 mg/kg; EGCG 17 mg/kg)] and weekly intramuscular doses (curcumin, 60 mg/kg; EGCG 17 mg/kg)] for 28 days. Rats were …

Efficacy Of Human Placental-Derived Stem Cells In Collagen Vii Knockout (Recessive Dystrophic Epidermolysis Bullosa) Animal Model, Yanling Liao, Larisa Ivanova, Rajarajeswari Sivalenka, Trevor Plumer, Hongwen Zhu, Xiaokui Zhang, Mitchell S. Cairo

NYMC Faculty Publications

Recessive dystrophic epidermolysis bullosa (RDEB) is a devastating inherited skin blistering disease caused by mutations in the COL7A1 gene that encodes type VII collagen (C7), a major structural component of anchoring fibrils at the dermal-epidermal junction (DEJ). We recently demonstrated that human cord blood-derived unrestricted somatic stem cells promote wound healing and ameliorate the blistering phenotype in a RDEB (col7a1(-/-) ) mouse model. Here, we demonstrate significant therapeutic effect of a further novel stem cell product in RDEB, that is, human placental-derived stem cells (HPDSCs), currently being used as human leukocyte antigen-independent donor cells with allogeneic umbilical cord blood stem …

Occupational Justice Concerns For Muslim Refugees In The United States, Emily Adams, Megan Peterson

Occupational Therapy Capstones

Background: Individuals are being displaced at alarming rates and many are from countries with a Muslim majority. Countries are beginning to study the effects of trauma and displacement on quality of life for refugees. The United States however, is lacking in studies involving health care, quality of life, and occupational justice concerns with Muslim refugees.

Objectives: To identify the experiences of Muslim refugees resettling in the United States and the resulting occupational justice issues, using Occupational Perspective of Health (Wilcock & Hocking, 2015) as an overarching theory.

Methods: Participants were obtained through convenience and snowball sampling. Participants …

Wild-Type P53 Enhances Endothelial Barrier Function By Mediating Rac1 Signalling And Rhoa Inhibition, Nektarios Barabutis, Christiana Dimitropoulou, Betsy Gregory, John D. Catravas

Bioelectrics Publications

Inflammation is the major cause of endothelial barrier hyper-permeability, associated with acute lung injury and acute respiratory distress syndrome. This study reports that p53 "orchestrates" the defence of vascular endothelium against LPS, by mediating the opposing actions of Rac1 and RhoA in pulmonary tissues. Human lung microvascular endothelial cells treated with HSP90 inhibitors activated both Rac1- and P21-activated kinase, which is an essential element of vascular barrier function. 17AAG increased the phosphorylation of both LIMK and cofilin, in contrast to LPS which counteracted those effects. Mouse lung microvascular endothelial cells exposed to LPS exhibited decreased expression of phospho-cofilin. 17AAG treatment …

Development And Evaluation Of Post-Production Oxygenation Techniques For The Augmentation Of Biochar, Matthew David Huff

Chemistry & Biochemistry Theses & Dissertations

Biochar is the carbon rich solid by-product of biomass pyrolysis. Interest in biochar can be broken down to several main categories: use as a carbon sequestration agent, use as a medium for the removal via adsorption of unwanted materials in wastewater, and as a soil amendment for the increase of cation exchange capacity (CEC). In order to generate a biochar which is stable enough for carbon sequestration, higher temperature pyrolysis must be used in order to ensure a lower O:C ratio in order to increase the half-life of biochar in soil. This dissertation addresses the evaluation of biochars made from …

Wet And Dry Atmospheric Deposition Of Nutrients And Bioactive Trace Metals To Coastal Waters Of The Mid-Atlantic Bight, Christine Sookhdeo

OES Theses and Dissertations

Atmospheric deposition provides a significant source of nutrients and bioactive trace metals to the surface ocean, including the seasonally oligotrophic waters of the Mid-Atlantic Bight. These atmospherically derived nutrients and trace metals enter the surface ocean via dry deposition of aerosols and wet deposition in rain. To estimate the aeolian input of nutrients and trace metals to coastal waters east of the Delmarva Peninsula, wet and dry atmospheric deposition samples were collected over a one-year time series at the Anheuser-Busch Coastal Research Center, Oyster, Virginia. Weekly composite samples were collected from May 2014 through June 2015. Nutrient species examined were …

Opioids Delay Healing Of Spinal Fusion: A Rabbit Posterolateral Lumbar Fusion Model, Nikhil Jain, Khaled Himed, Jeffrey M. Toth, Karen C. Briley, Frank M. Phillips, Safdar N. Khan

Biomedical Engineering Faculty Research and Publications

Background Context

Opioid use is prevalent in the management of pre- and postoperative pain in patients undergoing spinal fusion. There is evidence that opioids downregulate osteoblasts in vitro, and a previous study found that morphine delays the maturation and remodeling of callus in a rat femur fracture model. However, the effect of opioids on healing of spinal fusion has not been investigated before. Isolating the effect of opioid exposure in humans would be limited by the numerous confounding factors that affect fusion healing. Therefore, we have used a well-established rabbit model to study the process of spinal fusion healing that …

Taxpayers For Public Education V. Douglas County School District: The School Choice Movement Soldiers On, Bryce Carlson

University of Colorado Law Review

For nearly a decade, the school choice movement in Colorado has hung in the balance as the fate of the Douglas County School District Choice Scholarship Program worked its way through the courts, even reaching the United States Supreme Court in the process. The main issue at stake was whether Article IX, § 7 of the Colorado Constitution, which prevents public institutions from making any appropriation to a "church or sectarian society," barred students from using a school district scholarship to attend a private religiously affiliated school.

The Colorado Supreme Court in 2015 ruled that the Choice Scholarship Program indeed …

Ecotypes And Killer Whales: A Scientific Concept To Guide The Endangered Species Act's "Distinct Population Segment", Christopher Michael Johnson

University of Colorado Law Review

The Endangered Species Act protects threatened and endangered species, subspecies, and distinct population segments, with species listings guided by the best scientific information available. "Distinct population segment," however, is not a biological term. To date, there is still not a test based on evolutionary theory used to determine distinct population segments. This Comment attempts to change that by introducing the ecotype concept-a scientific theory that has existed for over one hundred years-into jurisprudence. This Comment begins by recounting how the distinct population segment terminology came to be. Next, it argues that the Endangered Species Act has been implemented contrary to …

Animal Property Rights, Karen Bradshaw

University of Colorado Law Review

The animal rights movement largely focuses on protecting species whose suffering is most visible to humans, such as pets, livestock, and captive mammals. Yet, we do not observe how unsustainable land development and fishing practices are harming many species of wildlife and sea creatures. Fish and wildlife populations have recently suffered staggering losses, and they stand to lose far more. This Article proposes a new legal approach to protect these currently overlooked creatures. I suggest extending property rights to animals, which would allow them to own land, water, and natural resources. Human trustees would manage animal-owned trusts managed at the …

Identity Harm, Sarah Dadush

University of Colorado Law Review

In September 2015, the world learned that Volkswagen had rigged millions of its "clean diesel" vehicles with illegal software designed to cheat emissions tests. Contrary to what had been advertised, the vehicles are anything but clean. When affected owners learned that their cars were toxic, what were they most upset about? Was it that their cars were now worth fewer dollars? Or that they had been deceived into being hyperpolluting drivers, when they thought they were being green? Coverage of the emissions scandal strongly suggests that affected car owners experienced both kinds of disappointment, economic and noneconomic, and in heavy …

Table Of Contents (Vol. 89, Issue 3)

University of Colorado Law Review

No abstract provided.

Exercise For People With Parkinson’S: A Practical Approach, Bhanu Ramaswamy, Julie Jones, Camille Carroll

Peninsula Medical School

No abstract provided.

Clinical Chronobiology: A Timely Consideration In Critical Care Medicine, Helen Mckenna, Der Horst Gtj Van, Irwin Reiss, Daniel Martin

Peninsula Medical School

No abstract provided.

Differential Phosphorylation And N-Terminal Configuration Of Capsid Subunits In Parvovirus Assembly And Viral Trafficking, J Gil-Ranedo, E Hernando, N Valle, L Riolobos, B Maroto, Jm Almendral

Peninsula Medical School

No abstract provided.

Improving Methods To Estimate Time Of Death From Body Temperature, Carly Berdan

Theses

By protocol, ambient and body temperatures are collected at every investigated death scene. These data has been used since 1839 to estimate the time of death, a crucial factor when it comes to cases of unnatural deaths and homicides. The Glaister Equation and Henssge's nomogram, commonly used to calculate estimated time of death, are inconsistent and often do not agree with each other. Therefore, my objective was to evaluate and improve them.

I collected data in the field and consistently measured temperature data. Furthermore, I was granted access to a database of every death in New Jersey and published data. …

Changes In Nadph Oxidase (Nox) Protein Isoforms And Downstream Reactions As Function Of Time And Overpressure In Blast Tbi, Smit Prakash Shah

Theses

Blast-induced Traumatic brain injury (bTBI) is a leading cause of morbidity in soldiers on the battlefield and training sites with long-term neurological and psychological pathologies. Among many pathological sequela of blast TBI, oxidative stress has been identified as a major factor contributing to the pathophysiology of bTBI. Recent studies have demonstrated activation of oxidative stress pathways following blast injury but their distribution among different brain regions as function of post injury time and Blast over pressure (BOP) have not been explored. The present study examines the protein expression of NADP oxidase (NOX) isoforms 1 & 2, corresponding superoxide production, a …

Shooting Down Oliphant: Self-Defense As An Answer To Crime In Indian Country, Adam Crepelle

Lewis & Clark Law Review

Crime is a dire public safety problem in Indian country as Indians suffer violent crime at twice the rate of any other racial group. Indian country’s unique and confusing jurisdictional scheme combined with a shortage of police leave Indians easy targets for those looking to commit crimes. A largely unexplored answer to crime in Indian country is self-defense. This Article posits that the United States self-defense jurisprudence may make self-defense the most practical solution to crime in some parts of Indian country.

The Article discusses the history of self-defense laws and the relationship between self-defense laws and firearms. The Article …