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Characterizing The Functional Role And Regulated Assembly Of Protein Polymers Mind And Ftsa During Escherichia Coli Cell Division, Joseph Jake Conti

Open Access Dissertations

It is an immense undertaking for any organism, including a bacterium, to self-replicate. Accurate and rapid division is essential for bacteria to proliferate and produce progeny, especially in environments where there is competition for resources. The nucleoid, the region of the cell that contains the DNA, harbors the genetic information required to achieve robust division, but it is the assembly of the cell division machinery, collectively referred to as the divisome, that produces and coordinates the mechanical force necessary to divide a cell. The hallmark of prokaryotic cell division is the formation of a protein super-structure, called the Z-ring, which …

Experimental And Numerical Simulations For Fluid Body Interaction Problems, Amin Mivehchi

Open Access Dissertations

This dissertation focuses on the experimental and numerical modelling of fluid structure interaction (FSI) problems. The main objective of this work was to develop state-of-art experimental and numerical tools to investigate a variety of Fluid-Structure Interaction problems. This topic is of critical importance to Naval Hydrodynamics and offshore applications, such as in ship design, floating offshore wind platforms and offshore ocean energy systems.

On the experimental modelling of FSI, this dissertation includes detailed of state-of-art hydrodynamic testing tank system for studying biomimetic fluid-structure interaction problems. This system was employed to study unsteady ground effect for pitching and heaving flapping foil …

Condemnation Of Religious Concepts: An Examination Of Chubak's "An Afternoon In Late Autumn" Through Bakhtin's Theory Of Grotesque Realism, Sayed Mohammad Anoosheh, Muhammad Hussein Oroskhan

Khazar Journal of Humanities and Social Sciences

The first traces of modernism in Iranian society can be found in the second decade of twentieth century which was deeply embedded with religious concepts. With regard to Persian literature, short story was developed as a new genre and a sign of modernism of that period by prominent Iranian writers such as Sadeq Hedayat (1903-1951), Mohammad Ali Jamalzadeh (1892-1997) and Sadegh Chubak (1916-1998). In this way a cultural clash was broken out between the traditional religious concepts and the new modern ideas. Among these writers, Chubak was more influenced by the doctrine of modernism. He expressed his message colloquially through …

A Comparison Of The Antimicrobial Efficacy Of Silver Diamine Fluoride And Silver Nitrate: An Ex Vivo Study, Reham M. Alnajjar

Theses and Dissertations

A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate on various cariogenic bacteria: an ex vivo study By: Reham AlNajjar, D.D.S.

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, 2019

Thesis Advisor: William Dahlke, D.M.D., Associate Professor and Chair of Pediatric Dentistry, School of Dentistry

Purpose: The use of silver-based antimicrobials is an emerging method for the treatment of dental caries. In this study, the authors compare the efficacy of the two most prominent silver- based therapeutics, silver diamine …

The Consensus Myth In Criminal Justice Reform, Benjamin Levin

Publications

It has become popular to identify a “consensus” on criminal justice reform, but how deep is that consensus, actually? This Article argues that the purported consensus is much more limited than it initially appears. Despite shared reformist vocabulary, the consensus rests on distinct critiques that identify different flaws and justify distinct policy solutions. The underlying disagreements transcend traditional left/right political divides and speak to deeper disputes about the state and the role of criminal law in society.

The Article maps two prevailing, but fundamentally distinct, critiques of criminal law: (1) the quantitative approach (what I call the “over” frame); and …

Youtube Ted Talk Comment Sentiment Data, Royce Kimmons

ScholarsArchive Data

This dataset includes comments to all available TED Talk videos on YouTube. Videos are coded for presenter gender and format, and comments are coded for sentiment using SentiStrength.

Brain-Computer Interface: Controlling A Robotic Arm Using Facial Expressions, Humaira Nisar, Hong-Way Khow, Kim Ho Yeap

Turkish Journal of Electrical Engineering and Computer Sciences

The aim of this paper is to develop a brain-computer interface (BCI) system that can control a robotic arm using EEG signals generated by facial expressions. The EEG signals are acquired using a neurosignal acquisition headset. The robotic arm consists of a 3-D printed prosthetic hand that is attached to a forearm and elbow made of craft wood. The arm is designed to make four moves. Each move is controlled by one facial expression. Hence, four different EEG signals are used in this work. The performance of the BCI robotic arm is evaluated by testing it on 10 subjects. Initially …

Studies On Selected Enzymes Involved In Ubiquinone Biosynthesis In Escherichia Coli, Debarati Ghose

Graduate Research Theses & Dissertations

Escherichia coli synthesize an important component of the electron transport chain, Coenzyme Q (Ubiquinone; Q) from the shikimate pathway intermediate, chorismate. Two isofunctional enzymes UbiD and UbiX are responsible for the decarboxylation step in Q biosynthesis. It was shown by Gulmezian et al. (2007) that the loss of ubiX+ gene leads to a reduction in growth in both rich and minimal media as well as decrease in Q. They further reported that UbiX is responsible for controlling the activity of UbiG O-methyltransferase, involved in two O-methylation reactions in Q biosynthesis. Contrary to these results, in this study we show that …

Here Comes The Monkey! : Best Practices For Using Student Test Scores As Part Of The Teacher Evaluation Process Based On An Analysis Of Legislation And Litigation In Early-Adopting Race To The Top States, Julie Dausey Oziemkowski

Graduate Research Theses & Dissertations

Numerous lawsuits have been filed against school officials since the first Race to the Top (RTTT) monies were awarded in 2011, requiring school districts in participating states to incorporate student scores on standardized tests into their teacher evaluation processes. This study researched the history of standardized testing in the United States from Horace Mann to Common Core, the timeline of education reform in the United States, changes to state statutes in response to the federal Race to the Top program, and litigation filed in early-adopting RTTT states in response to the student growth component. It concludes with findings that provide …

Revisiting Seminole Rock, Jeffrey A. Pojanowski

Journal Articles

The rule that reviewing courts must defer to agencies’ interpretations of their own regulations has come under scrutiny in recent years. Critics contend that this doctrine, often associated with the 1997 Supreme Court decision Auer v. Robbins, violates the separation of powers, gives agencies perverse regulatory incentives, and undermines the judiciary’s duty to say what the law is.
/="/">
/="/">This essay offers a different argument as to why Auer is literally and prosaically bad law. Auer deference appears to be grounded on a misunderstanding of its originating case, the 1945 decision Bowles v. Seminole Rock. A closer look at …

Responding To Small Island Nations Imperiled By Human-Forced Climate Change: An Ethical Imperative For Christians, Jame Schaefer

Theology Faculty Research and Publications

Small island nations are increasingly imperiled by larger nations that are emitting most of the greenhouse gases, forcing changes in the global climate, and causing catastrophic ecological and social problems. Among the most adversely affected people are islanders who are suffering immense health, economic, and cultural injustices that should be addressed at all levels of governance. Leaders of Anglican, Eastern Orthodox, and Roman Catholic denominations have been responding meaningfully to the plight of the small island nations by drawing motivation from their theological traditions for mitigating the problems and calling all Christians to act individually, collectively within their parishes, and …

Converting To And Nurturing Ecological Consciousness--Individually, Collectively, Actively, Jame Schaefer

Theology Faculty Research and Publications

No abstract provided.

Converting To And Nourishing Ecological Consciousness-Individually And Collectively, Jame Schaefer

Theology Faculty Research and Publications

No abstract provided.

The Unity Of The Virtues In A Missionary Key, Andrew J. Kim

Theology Faculty Research and Publications

The thesis of the unity of the virtues—one must possess all of the virtues to possess even one of them—was upheld in different forms by Plato, Aristotle, Augustine, and Aquinas. However, contemporary moralists almost universally decry this thesis as distorting the nature of virtue as it is materialized in the lives and actions of ordinary people. Unfortunately, academic discourse regarding the unity of the virtues has tended to be either entirely theoretical or narrowly limited to particular individuals or groups as “test cases” regarding the validity of the thesis. It is both significant and reinvigorating, therefore, that in his apostolic …

Book Review Of On Love, Confession, Surrender And The Moral Self, By Ian Clausen, Andrew J. Kim

Theology Faculty Research and Publications

No abstract provided.

Water Supply Planning In Virginia: The Future Of Groundwater And Surface Water, Jonathon Lubrano, Jeffrey Moore

Virginia Coastal Policy Center

This paper begins by exploring the current state of water resources planning and permitting. Then, considers current water demand in Virginia, as well as future challenges. Next is an examination of management structures from other states and a discussion of potential solutions to the water scarcity issue, including wastewater purification, the Hampton Roads Sanitation District’s (HRSD) Sustainable Water Initiative For Tomorrow (SWIFT) project, and desalination. The paper concludes with various next steps and policy recommendations that the Commonwealth should consider as dwindling water resources could hamper economic growth and threaten drought conditions, such as regional planning to achieve the optimal …

Design, Synthesis And Biological Evaluation Of Inhibitors Against Both Human And Mouse Microsomal Prostaglandin E2 Synthase-1 Enzymes, Kai Ding

Theses and Dissertations--Chemistry

As the principal pro-inflammatory prostanoid, prostaglandin E₂ (PGE₂) serves as mediator of pain and fever in inflammatory reactions. The biosynthesis of PGE₂ starts from arachidonic acid (AA). Cyclooxygenase (COX)-1 and/or COX-2 converts AA to prostaglandin H₂ (PGH₂), and PGE₂ synthases transform PGH₂ to PGE₂. Current mainstream approach for treating inflammation-related symptoms remains the application of traditional non-steroidal anti-inflammatory drugs (tNSAIDs) and selective COX-2 inhibitors (coxibs). As both categories shut down the biosynthesis of all downstream prostanoids, their application renders several deleterious effects including gastrointestinalulceration and cardiovascular risk. Microsomal prostaglandin …

Increasing Living Shoreline Implementation In Virginia: Legal And Policy Recommendations, Christopher Antoine

Virginia Coastal Policy Center

When living shorelines are correctly implemented, they can provide a number of benefits to landowners, localities, and the state. Based on that knowledge, in 2011, the Virginia General Assembly codified a preference for the use of living shorelines in tidal shoreline stabilization projects to facilitate a greater realization of those benefits. Despite the statutory preference, much of Virginia’s tidal shoreline may not be realizing the benefits associated with living shorelines. A recent report from the Center for Coastal Resources Management (CCRM) at the Virginia Institute of Marine Science indicated that, in a sample of coastal Virginia localities from 2014-2016, as …

Women And The Experience Of Pain And Opioid Use Disorder: A Literature-Based Commentary, Andrew L. Koons, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do, Gillian A. Beauchamp Md

Department of Emergency Medicine

It is generally understood that pain experience and opioid abuse have relied on male-dominated models. However, sex and gender play a role in both pain experience and opioid use disorder.

Using the previously validated Texas Tech University Health Sciences Center Sex and Gender Specific Health PubMed Advanced Search Tool, the authors used pertinent literature to develop this literature-based commentary on sex and gender differences in pain experience and opioid use disorder. Women report their experience of pain more frequently, have increased rates of diagnoses related to pain, have increased pain sensitivity, and have a variable response to pain and analgesia. …

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 67, Issue 1, Winter 2018

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• Dean's Column
• Findings: "Living Electrodes" may change neurological device design
• Ch-ch-ch-changes: Jefferson's realignment of departments and programs
• The Difference Alumni Make: A message from Elizabeth Dale
• A Fighting Chance: Harrisburg's boxing scene has an unlikely ally in cardiologist Andrew Foy, MD '08
• Alumni Weekend
• 2017 Jefferson Gala: Gathering to celebrate our shared success
• Time Capsule
• The Shot Doc: Meet Herb Magee, head coach of Jefferson's men's basketball team, the Rams
• Going the Distance: Students bring compassion into the clinic in Nicaragua's remote mountains
• On Campus
• Stephanie Moleski, MD '05: Jefferson doctor moves from board room to exam …

Zora Neale Hurston’S Moses, Man Of The Mountain And Biblical Studies, Deirdre Dempsey

Theology Faculty Research and Publications

No abstract provided.

Lessons From Medellín For Just Health Care: Catholic Ministry, Incarnation, And Participation, Alexandre A. Martins

Theology Faculty Research and Publications

No abstract provided.

Non Abbiamo Una Città Permanente, Ma Cerchiamo Quella Futura” (Eb. 13,14): “Xeniteía” E “Philoxenía” Nella Tradizione Ortodossa, Marcus Plested

Theology Faculty Research and Publications

No abstract provided.

Thomas Hobbes On Inequality, Poverty And Sedition : A Seventeenth-Century Blueprint For The Welfare State, Richard Rivard

Graduate Research Theses & Dissertations

Thomas Hobbes is often portrayed as a proponent of an absolutist government ruled only through fear of punishment. This portrayal overlooks the concern Hobbes had for the safety and security of the citizens of the commonwealth. Inequality and poverty were major concerns for Hobbes as they serve as pathways to sedition and the dissolution of the commonwealth. This essay emphasizes Hobbes's concerns with respect to inequality and poverty. Hobbes's laws of nature provide a blueprint for a welfare state that addresses these issues. The sovereign is obliged to follow the laws of nature and therefore the blueprint for the welfare …

Using Semantic And Pragmatic Information To Determine Syntactic Decisions In Translation Of The Passive Voice From English To French, Ashli Fain

Graduate Research Theses & Dissertations

I investigated statistically significant factors that effect syntactic changes in French and

English during translation of by phrases using the passive voice. Relative clauses containing this

structure were also looked at. This feature was chosen from information that was gathered from

experts in the form of academic texts on English-French translation, as well as handbooks

intended for an audience of professional translators. Data came from the proceedings of the

Canadian Parliament (the Hansard), which are published in French and English. Passive

sentences were collected from the output of the Stanford Parser. Animacy was found to be a

significant factor in …

Evaluation Of Ispe For Inhibitor Design In The Non-Mevalonate Pathway, Kataryzna Barbara Hoerchler

Graduate Research Theses & Dissertations

There is an urgent need to discover new antibiotics to combat the emergence of drug resistant Novel antibiotics that target unique pathways different from existing therapies are promising targets. The non-mevalonate pathway (MEP), which was discovered in the 1990’s, is essential for most bacteria, plants and apicomplexan parasites. Inhibition of the non-mevalonate is an attractive pharmaceutical target, since it is not present in mammals. Many compounds have surfaced as potential inhibitors, but none have made it to market. This thesis investigates the fourth step in the MEP pathway involving the enzyme 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Escherichia coli (Ec), Burkholderia thailandensis …

Aftermath, David Aldridge

Mighty Pen Project Anthology & Archive

On his first day in the Vietnamese bush, a soldier takes upon himself to recover the body of a fallen comrade.

Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L. Robbins, and in partnership with Virginia Commonwealth University and the Virginia War Memorial in Richmond, Virginia, offers veterans and their family members a customized twelve-week writing class, free of charge. The program encourages, supports, and assists participants in sharing their stories and experiences of military experience so both writer and audience may benefit.

Development Of A Multi-Robot Testbed For Direct Human-Swarm Interaction, Venkata Satya Kiran Maridi

Graduate Research Theses & Dissertations

Robotic swarms are well suited for missions that involve covering large areas such as environmental monitoring, search-and-rescue operations, as well as those that require fusing information from multiple sources such as target tracking and machine inspection. However, navigating a swarm of robots effectively requires performing higher-level functions that are typically executed by humans such as commanding them to stay close and guiding them along with a preplanned route. In this context, the ability of multiple robots to stay together autonomously significantly reduces the cognitive load on a human operator. The goal of this thesis is to design and build a …

Does Infant Negative Affect Moderate The Impact Of Parenting On Effortful Control? A Test Of The Differential Susceptibility Hypothesis, Anton Petrenko

Graduate Research Theses & Dissertations

Parenting and early temperament characteristics have previously been shown to impact development of children’s self-regulation, which is in turn linked to a variety of developmental outcomes. However, few studies have evaluated interactions between difficult temperament and parenting, and only four published studies have specifically tested whether infants’ difficult temperament serves as a maker of differential susceptibility to parenting on self-regulatory development. The current study evaluated whether infant negative affectivity (NA) serves as a marker of differential susceptibility to positive and negative parenting on levels of effortful control (EC) at 18 months, which is at an earlier time point than has …

Evaluating The Role Of Energy Demand Prediction And Renewable Energy Utilization On Energy Dependency Management: A Generic System Dynamics Model, Emad Rabiei Hosseinabad

Graduate Research Theses & Dissertations

Supplying energy has become one of the biggest concerns of developed countries due to the growing energy needs in the last decades. Security of energy supply has forced countries to rely more on energy imports from external sources, and become energy dependent to a greater extent. Utilizing available renewable energy resources has been characterized as a reliable indicator to mitigate energy dependency in countries as well as securing the supplying of energy-based needs in the future. This research explores the impact of renewable energies as trustful resources in mitigating energy imports form external sources with investigation of its viability with …