Digital Commons Network^™

On The Progenitor Of Binary Neutron Star Merger Gw170817, B. P. Abbott, K. Aultoneal, S. Gaudio, K. Gill, E. M. Gretarsson, B. Hughey, M. Muratore, J. W. W. Pratt, S. G. Schwalbe, K. Staats, M. J. Szczepańczyk, M. Zanolin, Et Al.

Publications

On 2017 August 17 the merger of two compact objects with masses consistent with two neutron stars was discovered through gravitational-wave (GW170817), gamma-ray (GRB 170817A), and optical (SSS17a/AT 2017gfo) observations. The optical source was associated with the early-type galaxy NGC 4993 at a distance of just ~40 Mpc, consistent with the gravitational-wave measurement, and the merger was localized to be at a projected distance of ~2 kpc away from the galaxy's center. We use this minimal set of facts and the mass posteriors of the two neutron stars to derive the first constraints on the progenitor of GW170817 at the …

Search For High-Energy Neutrinos From Binary Neutron Star Merger Gw170817 With Antares, Icecube, And The Pierre Auger Observatory, M. G. Aartsen, K. Aultoneal, S. Gaudio, K. Gill, E. M. Gretarsson, B. Hughey, M. Muratore, J. W. W. Pratt, S. G. Schwalbe, K. Staats, M. J. Szczepańczyk, M. Zanolin, Et Al.

Publications

The Advanced LIGO and Advanced Virgo observatories recently discovered gravitational waves from a binary neutron star inspiral. A short gamma-ray burst (GRB) that followed the merger of this binary was also recorded by the Fermi Gamma-ray Burst Monitor (Fermi-GBM), and the Anti-Coincidence Shield for the Spectrometer for the International Gamma-Ray Astrophysics Laboratory (INTEGRAL), indicating particle acceleration by the source. The precise location of the event was determined by optical detections of emission following the merger. We searched for high-energy neutrinos from the merger in the GeV–EeV energy range using the ANTARES, IceCube, and Pierre Auger Observatories. No neutrinos directionally coincident …

Estimating The Contribution Of Dynamical Ejecta In The Kilonova Associated With Gw170817, B. P. Abbott, K. Aultoneal, S. Gaudio, K. Gill, E. M. Gretarsson, B. Hughey, M. Muratore, J. W. W. Pratt, S. G. Schwalbe, K. Staats, M. J. Szczepańczyk, M. Zanolin, Et Al.

Publications

The source of the gravitational-wave (GW) signal GW170817, very likely a binary neutron star merger, was also observed electromagnetically, providing the first multi-messenger observations of this type. The two-week-long electromagnetic (EM) counterpart had a signature indicative of an r-process-induced optical transient known as a kilonova. This Letter examines how the mass of the dynamical ejecta can be estimated without a direct electromagnetic observation of the kilonova, using GW measurements and a phenomenological model calibrated to numerical simulations of mergers with dynamical ejecta. Specifically, we apply the model to the binary masses inferred from the GW measurements, and use the resulting …

A Pilot Study Of Computerized, Tailored Intervention To Promote Hpv Vaccination In Mexican-Heritage Adolescents, Angela Chia-Chen Chen, Michael Todd, Ashish Amresh, Usha Menon, Laura Szalacha

Publications

This study examined feasibility, acceptability, and preliminary effects of a computer-tailored intervention aimed at promoting HPV vaccination in Mexican-heritage adolescents aged 11-17. Among 46 Mexican-heritage parents who had one or more eligible children who had not received HPV vaccines, 91% (n = 42) completed the intervention and assessments via touchscreen tablet computers in a vaccine clinic. Mean knowledge scores increased significantly from pre- to post-intervention. After the intervention, 95% (n = 40) of parents intended to get their children vaccinated; 50% (n=21) of them consented to vaccination immediately, resulting in 24 adolescents being vaccinated at that time. All parents reported …

Ombuds As Nomads? The Intersections Of Dispute System Design And Identity, Tim Hedeen

Faculty Articles

Whether providing requested information, careful attention, informal coaching, impartial mediation, or upward feedback, ombuds operate within an “oscillating space” occasioned by contending purposes of their work. Their relationships to both their visitors and their host organization confer a dynamic identity, as they are at once supporting the visitor and supporting the organization. With which does an ombudsman identify, their organization or their visitor? Can the answer be both? This article will explore the opportunities and challenges arising from this tension.

Mcdi Rebranding Project And Strategic Marketing Plan, Maeve Greeley, Emily Turchin, Megan Cannella

Coal Region Field Station Student Projects

In this interdisciplinary, collaborative project, senior students from management and graphic arts worked with stakeholders in Mount Carmel, PA, to develop a strategic marketing plan and rebranding campaign for Mount Carmel Downtown Inc. (MCDI). This report describes that plan and includes a page by page review of the newly developed website and brand to accompany the campaign.

This project was developed by Maeve Greeley and Emily Turchin, Managing for Sustainability student researchers in a senior capstone independent study MSUS 310 taught by Prof. Eric Martin and Megan Cannella, a senior in ARST 336 Advanced Work in the Studio taught by …

A Comparison Of Mean Age Theory And Residence Time Distributions In Mixed Systems., Nolan Theaker

Electronic Theses and Dissertations

A comparison between mean age theory and conventional residence time distributions over a range of quantified mixing levels was conducted using computational fluid dynamics (CFD). The system was a stirred tubular reactor. The model was validated by comparing computationally derived RTD curves with experimentally obtained RTD curves, with quantified differences less than 3%. Mixing was quantified using the Tanks-in-Series model. Mixing levels were set by varying flow rate and impeller rpm. Mean age distributions at the outlet, where experimental RTD’s were measured, were very narrow for all levels of mixing studied. RTD’s showed expected characteristics; a wider distribution and long …

Winds Of Courage A Mallet Concerto For Solo Mallets And Wind Ensemble., Ross Elliott

Electronic Theses and Dissertations

Winds of Courage is a motivically-driven composition based on a repeating chordal pattern. Although being written out, the solo mallets parts sound somewhat improvisatory, which is a key element to the part. In a way, the concerto illustrates what it is like to have a crush on someone; where the first movement is getting up the courage to talk to them; the second movement, crying from failing to say what you need to say or not getting up the courage to talk to them, or getting rejected; and the final movement, when things work out in a positive manner, or …

Evaluating Ligand Assisted Activation Of Small Molecules Through Proton Reduction And Alcohol Oxidation., Rahul Jain

Electronic Theses and Dissertations

Hydrogen is a potential alternate to the carbon fuels to meet the future demands for energy in an eco-friendly manner. Hydrogen produced by the electrolysis of water is stored in fuel cells which on demand can be converted into electrical energy upon the reaction with oxygen. In the quest for economically viable electrocatalysts for hydrogen evolution, the work in this dissertation describes evaluation of nickel based catalysts coordinated to redox active ligands, dialkyl/diarylphosphine benzenethiol and bis(thiosemicarbazone) for their ability to generate hydrogen with external acids as a proton source. A nickel complex with the benzenethiol ligand framework follows a traditional …

A Framework For Clustering And Adaptive Topic Tracking On Evolving Text And Social Media Data Streams., Gopi Chand Nutakki

Electronic Theses and Dissertations

Recent advances and widespread usage of online web services and social media platforms, coupled with ubiquitous low cost devices, mobile technologies, and increasing capacity of lower cost storage, has led to a proliferation of Big data, ranging from, news, e-commerce clickstreams, and online business transactions to continuous event logs and social media expressions. These large amounts of online data, often referred to as data streams, because they get generated at extremely high throughputs or velocity, can make conventional and classical data analytics methodologies obsolete. For these reasons, the issues of management and analysis of data streams have been researched extensively …

Evaluating Work Place Wellness In Greater Louisville's Technology Organizations : A Case Study., Andrew L. Mccart

Electronic Theses and Dissertations

Employers in the Southern Indiana and Greater Louisville region are looking for strategies to help them become a healthier workplace. Many employers see the expense of paying for an unhealthy workforce and they are looking to limit these expenses. The purpose of the study is to determine the state of workplace wellness activities in organizations in Southern Indiana and Greater Louisville. Due to the poor health statuses of Indiana and Kentucky, 39th and 45th, respectively, this study is significant for a number of stakeholders in our area. The purpose of this case study was to understand the state of health …

Greater London In The 21st Century : Assessing Coastal Flooding Mitigation Preparedness And Regional Population Risk In The Face Of Projected Sea-Level Rise., Nathan K Wright

Electronic Theses and Dissertations

Recent projections of +6-9m sea-level rise (SLR) over the next several decades present many social challenges for coastal regions during the 21^st century. These projections were applied to Greater London, UK as areal interpolated historical census data was overlaid on a 50m DEM alongside a polyline projection of the Thames Barrier. Population was projected to milestones of 2041, 2071, and 2101 using a capped, aggregated growth rate for each polygon while SLR was simulated for 1m, 5m, and 9m scenarios. The Thames Barrier maintained integrity for 1m and 5m scenarios but was breached at 9m. Population continued to increase …

An Investigation Of Relationship Correlates And Predictors Of Cultural Adjustment Among Missionaries., Sarah Warren

Electronic Theses and Dissertations

While research on the cultural adjustment of expatriates has existed for decades, information related to the cultural adjustment of missionaries is considerably lacking (Kimber, 2012). Information on missionary cultural adjustment often has been extrapolated from the greater expatriate population, in spite of differences existing between missionaries and other expatriates (Navara & James, 2002; 2005). This study examined the extent to which missionary relationships (with God, individuals from one’s host culture, individuals from one’s home culture, and other missionaries) correlate with and predict cultural adjustment among missionaries. Participants were recruited from the Church of the Nazarene’s Global Mission Department to complete …

Moving Mountains : A Study Examining Long-Term Impacts Of Mountaintop Removal Coal Mining On Mortality In The Appalachian Region Using Geographic Information Sciences Techniques., James Howard Kent Pugh

Electronic Theses and Dissertations

Over the last hundred years, the Appalachian region has been dominated by the coal industry. It has also been and currently is one of the unhealthiest regions in the United States. Recent scholarship has examined the relationship between coal mining and health and mortality rates in the Appalachian region. The first study incorporates air quality and pollution data to examine if coal mining counties have higher levels of pollution and if this pollution contributes to mortality disadvantage. In the second study, I construct a population-based coal-exposure measure to better evaluate the relationship between coal mining and health I find that …

Sample Size Calculations And Normalization Methods For Rna-Seq Data., Xiaohong Li

Electronic Theses and Dissertations

High-throughput RNA sequencing (RNA-seq) has become the preferred choice for transcriptomics and gene expression studies. With the rapid growth of RNA-seq applications, sample size calculation methods for RNA-seq experiment design and data normalization methods for DEG analysis are important issues to be explored and discussed. The underlying theme of this dissertation is to develop novel sample size calculation methods in RNA-seq experiment design using test statistics. I have also proposed two novel normalization methods for analysis of RNA-seq data. In chapter one, I present the test statistical methods including Wald’s test, log-transformed Wald’s test and likelihood ratio test statistics for …

A Novel Approach To Assess Minimally Invasive Surgical Device Failure Utilizing Adverse Event Outcome Severity And Design Complexity., Marie K. Riggs

Electronic Theses and Dissertations

Medical device failure and misuse have the potential to cause serious injury and death. Given the intricate nature of the instruments utilized specifically in minimally invasive surgery (MIS), users and manufacturers of surgical devices share a responsibility in preventing user error and device failure. A novel approach was presented for the evaluation of minimally invasive device failures, which involved assessing the severity of adverse event outcomes associated with the failures modes and investigating aspects of the devices’ design that may contribute to failure. The goals of this research were to 1) characterize the design attributes, failure modes, and adverse events …

Age-Related Host Factors Regulate Lung Cancer Progression., John Caleb Greenwell

Electronic Theses and Dissertations

Cancer is largely a disease of the elderly. In the United States alone, 87% of all cancers in 2017 will be diagnosed in individuals aged 50 years or older. Among them, lung cancer is the deadliest, accounting for 1 in 4 cancer deaths. The 5-year survival rate is below 20%, a number which has not changed substantially over the past several decades. This underscores a desperate need for new strategies in prevention, early detection and treatment of this deadly disease. While tobacco use is unquestionably the number one risk factor for the development of lung cancer, the majority of diagnoses …

James Franklin Bell : Hard War In The Philippines., Daniel Michael

Electronic Theses and Dissertations

This thesis surveys the military history of the Philippine-American War of 1899-1902. In particular, this thesis looks at that war through the lens of hard war as a way of war. It begins with an introduction to hard war as a concept and a historiography of the Philippine-American War and continues with an overview of the events leading up to the war. The first two chapters deal with the wider role of the U.S. Army during the war, while the third chapter examines the role of James Franklin Bell, and American officer, and his command of the Third Separate Brigade …

Southern Veils : The Sisters Of Loretto In Early National Kentucky., Hannah O'Daniel

Electronic Theses and Dissertations

This thesis analyzes the experiences of Roman Catholic women who joined the Sisters of Loretto, a community of women religious in rural Washington and Nelson Counties, Kentucky, between the 1790s and 1826. It argues that the Sisters of Loretto used faith to interpret and respond to unfolding events in the early nation. The women sought to combat moral slippage and restore providential favor in the face of local Catholic institutional instability, global Protestant evangelical movements, war and economic crisis, and a tuberculosis outbreak. The Lorettines faced financial, social, and cultural pressures—including an economic depression, a culture that celebrated family formation …

Culturally Relevant Teachers : A Critical Beacon In The Educational Standards Movement., Angela Pleasant

Electronic Theses and Dissertations

The purpose of this study was to describe culturally relevant teachers’ beliefs and teaching practices as they implement the Reading CCSS. It was hypothesized that by exploring the beliefs and practices of teachers who practice a culturally relevant pedagogy, this research could provide evidence of the specific and identifiable practices that demonstrated high expectations, culturally competency, and critical consciousness. This research could provide evidence of effective strategies, which could be used to impact the literacy achievement of students of color while the teacher implements the Reading Common Core State Standards or any standards movement that follows. A qualitative case study …

Role Of Human Arylamine N-Acetyltransferase 1 In Tumorigenesis And Cancer Biology., Marcus William Stepp

Electronic Theses and Dissertations

Human arylamine N-acetyltransferase 1 (NAT1) is a well-known phase II metabolic enzyme that has been associated with carcinogenesis. Its role in the biotransformation of aromatic and heterocyclic amine carcinogens has been investigated for many years, but more recent investigations focus on a possible endogenous role of human NAT1 in cancer initiation and progression. To further explore and understand possible endogenous roles for NAT1, we conducted in vitro enzymatic reactions, in vivo studies using homozygous high (rapid) or low (slow) NAT2 activity congenic F344.WKY rats, and genetically modified human breast cancer cell lines. Human NAT1 and rodent NAT2 hydrolyzed acetyl-coenzyme …

Self-Management As A Mediator Of The Relationship Between Social Support And Health Outcomes Of African American Adults With Type 2 Diabetes., Tariq N. Al-Dwaikat

Electronic Theses and Dissertations

Type 2 diabetes (T2D) is often associated with serious complications. African American adults have higher rates of diabetes-related complications than other ethnicities. Diabetes self-management reduces the risk of developing biological and psychological symptoms. Social support promotes positive behavior change and self-management that leads to improved biobehavioral and psychosocial outcomes. Few studies explored the relationship between social support dimensions and self-management behaviors, diabetes biomarkers, and psychosocial outcomes of African American adults with T2D. The purpose of this dissertation was to examine the relationships of various dimensions of social support with self-management behaviors and diabetes biomarkers and psychosocial outcomes of African American …

Testing And Modeling Of The Thixotropic Behavior Of Cementitious Materials., Bashir Hasanzadeh

Electronic Theses and Dissertations

During construction, concrete goes under various operations. It is normally transported to the job site, be placed and consolidated in the formwork, etc. The easiness and quality of these operations are very much related to the intrinsic rheological properties of concrete. Therefore, a good understanding of rheological behavior of concrete under various conditions are needed. Thixotropy is an important part of rheology. The thixotropic behaviors of concrete can be good representatives of its flow behaviors on the job site. For example, the breakdown aspect of thixotropy can help to explain how its flow behavior can impact concrete pumping and its …

Heterogenization Of Complexes With Redox Active Ligands For Hydrogen Evolution Reaction., Wuyu Zhang

Electronic Theses and Dissertations

Hydrogen fuel is a promising future energy carrier with many applications. Thermodynamically, 1.23 V is needed for the water electrolysis, which is a clean method to generate hydrogen gas. In practice excess potential is required, which is called overpotential, due to kinetic barriers. Catalysts to reduce the overpotential for the hydrogen evolution reaction (HER) include many homogeneous catalysts and heterogeneous catalysts. Heterogenization of homogeneous catalysts on electrode surfaces is an ideal way to study a catalyst by combining homogeneous and heterogeneous study together. In this dissertation, several characterization techniques have been employed, include cyclic voltammetry, linear sweep voltammetry, electrochemical impedance …

Emotion Socialization And Families Of Children With And Without Adhd., Danielle M. Walerius

Electronic Theses and Dissertations

Emotional competence (EC) represents several distinct emotional skills found to be strongly associated with children’s socioemotional outcomes. EC is thought to develop through a process known as emotion socialization (ES), whereby children’s emotions and emotion-based behaviors are socialized through interactions with parents and/or other primary figures. The present study examined ES across families of children with and without ADHD in order to clarify the role ES plays in the development of EC in typically developing (TD) children versus children more prone to EC impairments due to intrapersonal characteristics (e.g., inattention, disinhibition, etc.). Forty-eight children 5 to 8-years-old (23 with ADHD, …

Farmscapes : Picturing Land Transformation In Nineteenth-Century America., Eileen L Yanoviak

Electronic Theses and Dissertations

This dissertation examines American farmstead imagery of the nineteenth-century and how those images reflect the environmental history of the North. In this study, images of farms illustrate, through the landscape, the transition from subsistence farming to agribusiness that fundamentally changed American life and the land over the century. By comparing the actual ecological and economic conditions of the farm and farmer to the images depicted by artists, it is possible to see both representations of change and the persistence of the agrarian myth in spite of dramatically different realities. This study focuses on the process of change in the American …

Modeling Effective Work Groups And Teams : An Assessment Of The Inclusion Of Social Value Orientation., Gary Daniel Jones

Electronic Theses and Dissertations

The purpose of this study is to examine research on effective work groups in terms of measurable input characteristics and relevant collective outputs. Antecedents and consequences of group processes are explored; models of work groups and teams are examined and assessed in light of subsequent research. Additionally, social value orientation – a behavioral trait known to predictably influence interpersonal outcomes – is introduced as a concept that is also relevant to group work. A revised model that includes social value orientation as a predictive factor for group productivity is presented and tested. This empirical study is a correlative, quantitative investigation …

Targeting The Major Regulator Of Mitosis., J. Mason Hoffman

Electronic Theses and Dissertations

Mitosis-inhibiting chemotherapeutics (e.g. taxanes) are frequently used to treat multiple cancer types. Recently, there has been much concern about the limited success of these drugs due to resistance and a lack of molecular targets. Thus, there is high demand for new drugs with diverse cellular targets. Targeting the regulators of mitosis is a promising approach. The anaphase promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that controls cell cycle progression at multiple points. The interaction of ANAPC2 and ANAPC11, catalytic core subunits, is necessary for APC/C function. An in silico approach was used to identify compounds predicted to prevent assembly …

Metabolic Regulation Of Myocardial Adaptation To Exercise., Andrew Alan Gibb

Electronic Theses and Dissertations

While the benefits of exercise affect several organs, a significant adaptive response occurs within the heart. Exercise promotes cardiac growth, increases angiogenesis, and enhances cardiac function and these adaptations are associated with a cardioprotective phenotype. Additionally, extensive evidence shows that exercise dynamically regulates myocardial metabolism. This can be attributed to both changes in hormonal stimulation, increases in bioenergetic demand, and the bioavailability of circulating substrates. However, it is unclear whether these changes in metabolism contribute to physiologic cardiac growth. We reason that exercise-induced changes in metabolism are required to balance the catabolic and anabolic reactions needed for growth. Specifically, we …

Understanding And Developing Estimates Based On Practical Foundation Methods For Alaska's Discontinuous Permafrost Region, Paul P. Dennison

Theses and Dissertations

This research uses a quantitative analysis to develop a family of curves and a calculator for potential foundation thresholds in the discontinuous permafrost region of Alaska. The United States Pacific Command (PACAF) is bolstering the region by advocating for the F-35, KC-46, and the newly proposed long-range bomber to be stationed in Alaska. These next generation aircrafts and warfighters will need new facilities and beddown plans to efficiently and effectively carry out their mission. The biggest obstacle in the region is permafrost; this unique polar phenomenon is found throughout the northern half of Alaska. Fairbanks in particular has multiple military …