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2017

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Articles 62461 - 62490 of 62840

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Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga Jan 2017

Unknown Vascular Compression Of The Airway In Patients With Congenitalheart Disease And Persistent Lower Respiratory Symptoms, Tuğba Şi̇şmanlar Eyüboğlu, Ayşe Tana Aslan, Çi̇ğdem Öztunali, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Serdar Kula, Betül Emi̇ne Deri̇nkuyu, Öznur Leman Boyunaga

Turkish Journal of Medical Sciences

Background/aim: Airway compression (AC) by vascular structures is an important complication of congenital heart disease (CHD) that often goes unrecognized. It is not easy to identify whether CHD patients require additional invasive examinations or not. Therefore, the present study aims to develop an AC diagnostic algorithm for CHD patients. Materials and methods: CHD patients with persistent respiratory symptoms that were treated between January 2007 and December 2015 were retrospectively reviewed. The following data were recorded for all CHD patients with AC: age, cardiac anomalies, the compressed structure, the airway diameter ratio (ADR), the compressing structure(s), treatment, and follow-up.Results: During the …

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Evaluation Of The General Characteristics Of Patients Aged 85 Years And Above Admitted To A University Hospital Emergency Department, Ahmet Demi̇rcan, Şahender Gülbi̇n Aygencel Bikmaz, Gülteki̇n Kadi, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Begüm Öktem, Onur Çakmak Jan 2017

Evaluation Of The General Characteristics Of Patients Aged 85 Years And Above Admitted To A University Hospital Emergency Department, Ahmet Demi̇rcan, Şahender Gülbi̇n Aygencel Bikmaz, Gülteki̇n Kadi, Ayfer Keleş, Fi̇kret Bi̇ldi̇k, Begüm Öktem, Onur Çakmak

Turkish Journal of Medical Sciences

Background/aim: The number of elderly people ($\ge$65 years old) is increasing both in Turkey and internationally due to improved living conditions and decreased mortality rates. Knowing the characteristics of elderly patients admitted to emergency departments can provide guidance for diagnosis and treatment approaches. In this study, we analyzed the characteristics of very old patients (4$\ge$85 years old) admitted to the emergency department and put together data for use in forward planning in healthcare services.Materials and methods: This retrospective study included all patients aged $\ge$85 years admitted to the Adult Emergency Department of Gazi University Medical Faculty Hospital between 01.01.2014 and …

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How To Manage Pseudoangiomatous Stromal Hyperplasia: Our Clinical Experience, Emi̇ne Kurt, Sevi̇m Turanli, Fatma Markoç, Ali̇ Uğur Berberoğlu Jan 2017

How To Manage Pseudoangiomatous Stromal Hyperplasia: Our Clinical Experience, Emi̇ne Kurt, Sevi̇m Turanli, Fatma Markoç, Ali̇ Uğur Berberoğlu

Turkish Journal of Medical Sciences

Background/aim: Pseudoangiomatous stromal hyperplasia (PASH) is a rare and benign mesenchymal proliferative breast lesion. Our aim is to review the clinical and radiological features of PASH and define a standard approach for its diagnosis and management. Materials and methods: Clinical records of 35 consecutive patients with PASH were retrospectively reviewed between 2009 and 2015. Patients with clinically or radiologically detected mass and patients who underwent biopsy for other indications and were diagnosed incidentally were included in the study. Results: There were 34 female patients and one male patient with gynecomastia. Twenty-three patients had palpable masses, and 16 of them were …

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Role Of Baseline Adenoma Characteristics For Adenoma Recurrencein Patients With High-Risk Adenoma, Tevfi̇k Solakoğlu, Hüseyi̇n Köseoğlu, Sevi̇l Özer Sari, Fatma Ebru Akin, Ayli̇n Demi̇rezer Bolat, Öykü Tayfur Yürekli̇, Naci̇ye Şemnur Büyükaşik, Osman Ersoy Jan 2017

Role Of Baseline Adenoma Characteristics For Adenoma Recurrencein Patients With High-Risk Adenoma, Tevfi̇k Solakoğlu, Hüseyi̇n Köseoğlu, Sevi̇l Özer Sari, Fatma Ebru Akin, Ayli̇n Demi̇rezer Bolat, Öykü Tayfur Yürekli̇, Naci̇ye Şemnur Büyükaşik, Osman Ersoy

Turkish Journal of Medical Sciences

Background/aim: The present observational study aimed to determine the predictive value of 3-year recurrence adenoma characteristics at baseline conventional colonoscopy in patients with high-risk adenoma.Materials and methods: A total of 47 patients with high-risk adenoma at baseline colonoscopy were followed up and underwent a surveillance colonoscopy at 3 years. Correlations between adenoma recurrence and baseline adenoma characteristics (size, number, histological features, and location) were analyzed.Results: Among 135 patients with high-risk adenoma, 47 patients (35%) who underwent surveillance colonoscopy at 3 years following baseline colonoscopy were included in the study. In these 47 patients, at least one new adenoma was detected …

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Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie Jan 2017

Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie

Turkish Journal of Medical Sciences

Background/aim: Helicobacter pylori (H. pylori) has a high prevalence in developing countries. We aimed to investigate the current prevalence of H. pylori, as well as its potential serum risk factors, in a population from southwest China.Materials and methods: This cross-sectional study included 10,912 subjects who received medical examinations at the First Affiliated Hospital of Chongqing Medical University in 2014. Data regarding physical examinations and biochemical measurements were collected, and H. pylori infection was diagnosed with a 13C-urea breath test. Logistic regression was conducted to identify the risk factors for H. pylori infection.Results: The infection rate of H. pylori was 34.4% …

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Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan Jan 2017

Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan

Turkish Journal of Medical Sciences

Background/aim: To determine the frequency, genotype distribution, and genetic relatedness of adenoviruses in children under 5 years old with diarrhoea and to investigate their distribution according to clinical findings, age, months, and seasons. Materials and methods: Stool samples were collected from 180 children with acute gastroenteritis who presented from July 2007 through June 2011 at the Ankara Training and Education Hospital. Stool samples were analysed by immune chromatographic test (ICT), enzyme immunoassay (EIA), and polymerase chain reaction (PCR). All adenovirus types were determined by nucleotide sequence analysis. A phylogenetic tree was constructed by Mega 6.0 using the neighbour-joining method. Results: …

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Multiplex Pcr Detection Of Problematic Pathogens Of Clinically Heterogeneous Bacterial Vaginosis In Bulgarian Women, Konstantsa Tosheva-Daskalova, Tanya Vasileva Strateva, Ivan Gergov Mitov, Raina Tzvetanova Gergova Jan 2017

Multiplex Pcr Detection Of Problematic Pathogens Of Clinically Heterogeneous Bacterial Vaginosis In Bulgarian Women, Konstantsa Tosheva-Daskalova, Tanya Vasileva Strateva, Ivan Gergov Mitov, Raina Tzvetanova Gergova

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the correlation between the prevalence of problematic pathogens and the clinical status of women with bacterial vaginosis (BV). Materials and methods: Gardnerella vaginalis, Atopobium vaginae, and Mobiluncus spp. were detected using a multiplex PCR assay, and their role in the infection of Bulgarian women with clinically heterogeneous BV was evaluated. Results: The predominant BV-associated pathogen identified was G. vaginalis with an incidence of 98.39%, followed by A. vaginae (68.05%) and Mobiluncus spp. at 17.01%. The coexistence of A. vaginae and G. vaginalis was more common in women with discharge (in 72.04%) and in patients …

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Investigation Of Human Leukocyte Antigen In Osteoarticular Brucellosis, Sevi̇m Gönen, Murat Di̇zbay, Hüsnü Oğuz Söylemezoğlu Jan 2017

Investigation Of Human Leukocyte Antigen In Osteoarticular Brucellosis, Sevi̇m Gönen, Murat Di̇zbay, Hüsnü Oğuz Söylemezoğlu

Turkish Journal of Medical Sciences

Background/aim: To determine the relationship between human leukocyte antigen (HLA) antigens and osteoarticular brucellosis by evaluating HLA Class I and II antigens in control subjects and patients developing osteoarticular brucellosis in Turkey.Materials and methods: The study included 28 patients with osteoarticular involvement diagnosed with brucellosis and 100 controls. The HLA Class I and II antigens were studied in isolated DNA samples using sequence-specific oligonucleotide procedure.Results: The mean age of the 28 patients and 100 controls was 42.3 $\pm$ 20.2 years and 50.1 $\pm$ 16.3 years, respectively. When the frequency of HLA Class I was examined, HLA-A*02 and HLA-B*27 antigens were …

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Mean Adc Values Discriminate Rectal Mucinous Carcinomafrom Rectal Nonmucinous Adenocarcinoma, Hale Çolakoğlu Er, Gül Ayşe Erden Jan 2017

Mean Adc Values Discriminate Rectal Mucinous Carcinomafrom Rectal Nonmucinous Adenocarcinoma, Hale Çolakoğlu Er, Gül Ayşe Erden

Turkish Journal of Medical Sciences

Background/aim: This study aimed to differentiate rectal mucinous carcinoma (MC) from nonmucinous rectal adenocarcinoma (AC) using mean apparent diffusion coefficient (mADC) values obtained with diffusion-weighted imaging.Materials and methods: Sixty-two pathologically confirmed rectal AC (n = 44) and MC (n = 18) patients were included in this study. The two groups underwent pelvic MRI to determine the local staging baseline for rectal tumors. Once the region of interest (ROI) was determined, a border was drawn around each hyperintense tumor (b = 1000 s/mm2 images). Following a repeat of this procedure for each patient, the ROIs were recorded to apparent diffusion coefficient …

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Evaluation Of Pulmonary Vein Anatomy Using 256-Slice Computed Tomography, Yinghong Shi, Shaohua Mi, Yunxia Shi, Hongbo Wang, Jian Li, Benxia Yu, Fengli Liu, Heng Ma, Bin Wang Jan 2017

Evaluation Of Pulmonary Vein Anatomy Using 256-Slice Computed Tomography, Yinghong Shi, Shaohua Mi, Yunxia Shi, Hongbo Wang, Jian Li, Benxia Yu, Fengli Liu, Heng Ma, Bin Wang

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate pulmonary vein (PV) anatomy using 256-slice computed tomography (CT), which may be necessary for electrophysiologists to know before radiofrequency catheter ablation (RFCA) therapy.Materials and methods: A total of 102 patients with paroxysmal and persistent atrial fibrillation underwent 256-slice cardiac CT angiography prior to catheter ablation. PV morphology, ostial diameter, ostial orientation, and distance from ostium to first bifurcation were evaluated using three-dimensional volume-rendering and multiplanar-reformatting technology. Results: We found that 72.5% of patients had four conventional PVs. On the right, 22.5% of patients had one accessory PV, 4.9% had 2 accessory PVs, 1% had …

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Analysis Of Recurrent Urethral Strictures Due To Iatrogenic Urethral Trauma, Fuat Kizilay, Adnan Şi̇mşi̇r, Mehmet Ceyhun Özyurt Jan 2017

Analysis Of Recurrent Urethral Strictures Due To Iatrogenic Urethral Trauma, Fuat Kizilay, Adnan Şi̇mşi̇r, Mehmet Ceyhun Özyurt

Turkish Journal of Medical Sciences

Background/aim: We aimed to analyze the effects of stricture location, etiology, age, and catheterization time on recurrence rate and recurrence time in patients who underwent direct vision internal urethrotomy (DVIU) for urethral strictures. Materials and methods: Patients were divided into three groups according to the location of the stricture: penile urethra, membranous urethra, and prostatic urethra strictures. Patients were also divided into three groups according to etiologic factors: strictures secondary to endoscopic procedures, urethral catheterization, and open or radical prostatectomy (anastomotic strictures were included in this group). Patients were also divided into three groups according to catheterization time: 5-7 days. …

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Polymorphisms Of Cancer-Related Genes And Risk Of Multipleprimary Malignancies Involving Colorectal Cancer, Peiguo Cao, Li Yu, Anshan Wu, Jingjing Li, Ling Liu, Chunlan Liu, Jianda Zhou, Ke Cao, Chengxian Guo Jan 2017

Polymorphisms Of Cancer-Related Genes And Risk Of Multipleprimary Malignancies Involving Colorectal Cancer, Peiguo Cao, Li Yu, Anshan Wu, Jingjing Li, Ling Liu, Chunlan Liu, Jianda Zhou, Ke Cao, Chengxian Guo

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the relationship between single nucleotide polymorphisms (SNPs) of cancer-related genes and the risk of multiple primary malignancies involving colorectal cancer.Materials and methods: We collected tissue samples from 22 multiple primary cancer patients with primary colorectal cancer and performed genotyping assay for 116 SNP loci from 62 genes encoding peptides functioning in various signaling pathways using the DNA MassARRAY system. The chi-square test was used to compare the differences in base frequencies between patients and a control Chinese population from HapMap through the NCBI database.Results: No significant differences in frequencies were detected for 81 SNPs …

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The Relationship Between The Degree Of Skin Fibrosis By Sonoelastography And The Degree Of Pulmonary Involvement In Scleroderma, Songül Çi̇ldağ, Mehmet Burak Çi̇ldağ Jan 2017

The Relationship Between The Degree Of Skin Fibrosis By Sonoelastography And The Degree Of Pulmonary Involvement In Scleroderma, Songül Çi̇ldağ, Mehmet Burak Çi̇ldağ

Turkish Journal of Medical Sciences

Background/aim: This study aimed to assess the relationship between skin fibrosis as determined by sonoelastography and the degree of pulmonary involvement as determined by high-resolution computed tomography (HRCT) in patients with diffuse cutaneous systemic sclerosis (dcSSc).Materials and methods: This prospective study included 40 patients with dcSSc. All patients with HRCT scans underwent conventional ultrasonography and sonoelastography to determine skin thickness and degree of fibrosis. The degree of fibrosis was classified according to color-scale sonoelastography. The degree of pulmonary involvement was classified according to HRCT grading groups. The relationship between skin fibrosis and pulmonary involvement was investigated.Results: There was a statistically …

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Efficacy Of Bispectral Index Monitoring For Prevention Of Anestheticawareness And Complications During Oocyte Pick-Up Procedure, Aykut Urfalioğlu, Mahmut Arslan, Süleyman Murat Bakacak, Hafi̇ze Öksüz, Ömer Faruk Boran, Gözen Öksüz Jan 2017

Efficacy Of Bispectral Index Monitoring For Prevention Of Anestheticawareness And Complications During Oocyte Pick-Up Procedure, Aykut Urfalioğlu, Mahmut Arslan, Süleyman Murat Bakacak, Hafi̇ze Öksüz, Ömer Faruk Boran, Gözen Öksüz

Turkish Journal of Medical Sciences

Background/aim: This study was planned by considering that the use of bispectral index (BIS) monitoring ensures sufficient depth of anesthesia and avoids anesthetic awareness and patient movement in the oocyte pick-up (OPU) procedure.Materials and methods: Ninety-eight patients undergoing OPU were randomly divided into 2 groups as the control group (n = 48) and BIS group (n = 50). After propofol and remifentanil induction, the control group was given additional propofol according to reaction response, while the BIS group was given propofol at BIS values of 60 and above with the aim that BIS values be 40?60. Total procedure time, recovery …

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Coexistence Of Idiopathic Granulomatous Mastitis And Erythemanodosum: Successful Treatment With Corticosteroids, Murat Akin, Harun Karabacak, Güldal Esendağli, Aydin Yavuz, Serap Gülteki̇n, Kürşat Di̇kmen, Hasan Bostanci Jan 2017

Coexistence Of Idiopathic Granulomatous Mastitis And Erythemanodosum: Successful Treatment With Corticosteroids, Murat Akin, Harun Karabacak, Güldal Esendağli, Aydin Yavuz, Serap Gülteki̇n, Kürşat Di̇kmen, Hasan Bostanci

Turkish Journal of Medical Sciences

Background/aim: Idiopathic granulomatous mastitis (IGM) is a rare, chronic inflammatory disease of the breast. Erythema nodosum (EN) is a rare extramammary manifestation of IGM. The purpose of this study is to determine the clinical and demographic characteristics of 11 IGM and EN patients and to evaluate the efficacy of methylprednisolone treatment. Materials and methods: In our series, ten patients had EN bilaterally, whereas one patient had a lesion of the right pretibial area. The mean age of the patients was 35.5 years (range: 29-45 years). IGM and EN were diagnosed by the necessary serological, microbiological, radiological, and histopathological examination. After …

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Effects Of Positive End-Expiratory Pressure On Intracranial Pressure During Pneumoperitoneum And Trendelenburg Position In A Porcine Model, Nurdan Bedi̇rli̇, Gökçen Emmez, Yusuf Ünal, Mehmet Tönge, Ömer Hakan Emmez Jan 2017

Effects Of Positive End-Expiratory Pressure On Intracranial Pressure During Pneumoperitoneum And Trendelenburg Position In A Porcine Model, Nurdan Bedi̇rli̇, Gökçen Emmez, Yusuf Ünal, Mehmet Tönge, Ömer Hakan Emmez

Turkish Journal of Medical Sciences

Background/aim: This study was undertaken to evaluate the effects of positive end-expiratory pressure (PEEP) levels on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) and to determine the appropriate PEEP level during steep Trendelenburg position combined with pneumoperitoneum.Materials and methods: Ten pigs were included in this study. Pneumoperitoneum and Trendelenburg position were maintained and PEEP titration was initiated. Arterial pressure, heart rate, arterial blood gas, ICP, and CPP were recorded at the following time points: baseline (T0), 30 min after positioning and pneumoperitoneum (T1), PEEP 5 (T2), PEEP 10 (T3), PEEP 15 (T4), and PEEP 20 (T5).Results: MAP significantly increased …

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Dna Methylation Of The Prestin Gene And Outer Hair Cell Electromotileresponse Of The Cochlea In Salicylate Administration*, Erdoğan Bulut, Meti̇n Budak, Levent Öztürk, Mehmet Turgay Türkmen, Cem Uzun, Tammam Si̇pahi̇ Jan 2017

Dna Methylation Of The Prestin Gene And Outer Hair Cell Electromotileresponse Of The Cochlea In Salicylate Administration*, Erdoğan Bulut, Meti̇n Budak, Levent Öztürk, Mehmet Turgay Türkmen, Cem Uzun, Tammam Si̇pahi̇

Turkish Journal of Medical Sciences

Background/aim: Activity of the prestin gene may have a role in the pathogenesis of salicylate-induced ototoxicity. We investigated DNA methylation for prestin gene exon 1 in salicylate-injected guinea pigs.Materials and methods: Fifteen guinea pigs (30 ears) underwent audiological evaluation including 1000 Hz probe-tone tympanometry and a distortion product otoacoustic emission (DPOAE) test. The animals were randomly divided into three groups. Groups 2 (8 ears) and 3 (14 ears) were injected with intramuscular saline and sodium salicylate (200 mg/kg), respectively twice daily for 2 weeks. Group 1 (8 ears) received no injection. DPOAE measurements were performed at baseline; after 1, 2, …

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Exogenous Erythropoietin Aggravates Retinal Neovascularizationin A Murine Model Of Proliferative Retinopathy, Ning Yang, Wenxi Zhang, Tao He, Yiqiao Xing Jan 2017

Exogenous Erythropoietin Aggravates Retinal Neovascularizationin A Murine Model Of Proliferative Retinopathy, Ning Yang, Wenxi Zhang, Tao He, Yiqiao Xing

Turkish Journal of Medical Sciences

Background/aim: Erythropoietin (EPO) has been proven recently to be a critical mediator in retinal neovascularization (RNV). Previous studies have indicated that the use of recombinant human EPO (rEPO) is a high risk factor in the development of retinopathy of prematurity. In this study, we aimed to investigate the effect of rEPO administration on RNV and its underlying mechanism in a mouse model of oxygen-induced retinopathy (OIR). Materials and methods: A murine model of OIR was used to generate RNV. After daily intraperitoneal injection of rEPO from postnatal day 12 (P12), mice were euthanized at P17. Whole-mount retina staining was used …

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Effects Of Valproic Acid On Sympathetic Activity And Left Ventricularmyocardial Remodelling In Rats During Pressure Overload, Yang Liu, Siyu Li, Zhigang Zhang, Zhanjun Lv, Huijie Jiang, Xiao Tan, Fengquan Liu Jan 2017

Effects Of Valproic Acid On Sympathetic Activity And Left Ventricularmyocardial Remodelling In Rats During Pressure Overload, Yang Liu, Siyu Li, Zhigang Zhang, Zhanjun Lv, Huijie Jiang, Xiao Tan, Fengquan Liu

Turkish Journal of Medical Sciences

Background/aim: Pressure overload induces cardiac remodelling and results in heart failure. Enhanced sympathetic outflow participates in the development of cardiac remodelling for the duration of pressure overload as an independent factor. Valproic acid has recently been shown to reduce neuronal injury and have antiinflammatory and antiapoptotic effects as a histone deacetylase inhibitor. We speculate that the drug plays a specific role in alleviating cardiac remodelling by inhibiting sympathetic activity. Materials and methods: Surgery of partial abdominal aortic constriction was performed on male Sprague-Dawley rats. After 4 weeks, animal models of pressure overload were validated and then valproic acid (300 mg/kg) …

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Reply To Letter To The Editor, Ju Tae Sohn Jan 2017

Reply To Letter To The Editor, Ju Tae Sohn

Turkish Journal of Medical Sciences

No abstract provided.

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Lack Of Mir143, Mir145, Mir184, Mir1224, And Mir29b1 Mutations In Keratoconus Pathogenesis, Nurullah Çağil, Nagi̇han Uğurlu, Cemi̇l Yunus Şahan, Serhat Sevli̇ Jan 2017

Lack Of Mir143, Mir145, Mir184, Mir1224, And Mir29b1 Mutations In Keratoconus Pathogenesis, Nurullah Çağil, Nagi̇han Uğurlu, Cemi̇l Yunus Şahan, Serhat Sevli̇

Turkish Journal of Medical Sciences

No abstract provided.

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Do Preoperative Oral Carbohydrates Improve Postoperative Outcomesin Patients Undergoing Coronary Artery Bypass Grafts?, Ömer Faruk Şavluk, Mehmet Ali̇ Kuşcu, Füsun Güzelmeri̇ç, Mustafa Emre Gürcü, Atakan Erkilinç, Deni̇z Çevi̇rme, Hali̇de Oğuş, Tuncer Koçak Jan 2017

Do Preoperative Oral Carbohydrates Improve Postoperative Outcomesin Patients Undergoing Coronary Artery Bypass Grafts?, Ömer Faruk Şavluk, Mehmet Ali̇ Kuşcu, Füsun Güzelmeri̇ç, Mustafa Emre Gürcü, Atakan Erkilinç, Deni̇z Çevi̇rme, Hali̇de Oğuş, Tuncer Koçak

Turkish Journal of Medical Sciences

Background/aim: The aim of this prospective study was to determine whether the preoperative oral intake of carbohydrate-rich drinks by patients undergoing a coronary artery bypass graft attenuates postoperative insulin requirements, improves postoperative patient discomfort, provides inotropic support, shortens the length of the ICU stay, and shortens the duration of postoperative mechanical ventilation. Materials and methods: This randomized prospective clinical study included 152 patients with coronary artery disease who were divided into 4 groups. Carbohydrates were administered to 3 groups at different hours and doses before operation. The fourth group had an 8-h preoperative fasting period. The inotropic and vasopressor requirements, …

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Superiorly Based Nasolabial Island Flap For Reconstruction Of The Lateral Lower Eyelid, Sedat Tatar, Yalçin Yontar, Selahatti̇n Özmen Jan 2017

Superiorly Based Nasolabial Island Flap For Reconstruction Of The Lateral Lower Eyelid, Sedat Tatar, Yalçin Yontar, Selahatti̇n Özmen

Turkish Journal of Medical Sciences

Background/aim: Various flap procedures have been described and used for the lower eyelids; however, the nasolabial flap is rarely employed. We herein aimed to present the clinical results of using the superiorly based nasolabial island flap for repair of surgical defects extending to the lateral lower eyelid. Materials and methods: Nine patients with a mean age of 62 +- 6 years underwent surgery for reconstruction of the lower eyelid.Results: The diagnosis of lesions was nodular basal-cell carcinoma (n = 5), superficial basal-cell carcinoma (n = 1), well-differentiated squamous-cell carcinoma (n = 1), and basosquamous-cell carcinoma (n = 2). According to …

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An Examination Of Healthcare-Associated Infections In Elderly Patients, Serap İskender, Gürdal Yilmaz, İftahar Köksal Jan 2017

An Examination Of Healthcare-Associated Infections In Elderly Patients, Serap İskender, Gürdal Yilmaz, İftahar Köksal

Turkish Journal of Medical Sciences

Background/aim: Healthcare-associated infections (HCAIs) are increasing due to the growing numbers of elderly people requiring long-term care and immunosuppressive therapies. The purpose of this study was to examine HCAIs occurring in elderly inpatients in our hospital.Materials and methods: This study prospectively investigated HCAIs developing in all patients hospitalized over a 1-year period. Diagnosis was based on Centers for Disease Control criteria. The results were subjected to statistical analysis between patients aged over and under 65.Results: A total of 24,692 patients were evaluated and 894 HCAIs were identified. Of these infections, 214 were seen in patients aged 65 or over. The …

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Does Fibromyalgia Have An Effect On Hearing Loss In Women?, Zeli̇ha Kapusuz Gencer, Özlem Balbaloğlu, Mahmut Özkiriş, Levent Saydam Jan 2017

Does Fibromyalgia Have An Effect On Hearing Loss In Women?, Zeli̇ha Kapusuz Gencer, Özlem Balbaloğlu, Mahmut Özkiriş, Levent Saydam

Turkish Journal of Medical Sciences

Background/aim: Fibromyalgia (FM) patients may have several neuroendocrine dysfunctions, resulting in a hypervigilant sensory output that may be responsible for sensorineural complaints. In this study, we evaluated the audiological findings of a cohort of female fibromyalgia patients. Materials and methods: Between 1 September 2012 and 1 June 2013, 35 female FM patients, followed by the Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Bozok University, were recruited for the study. The patients were referred to the Department of Otolaryngology for routine otolaryngological and audiological evaluations. Age range was between 30 and 65 years, with a mean age of 48.10 …

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Evaluation Of The Effects Of Montelukast, Mometasone Furoate, And Combined Therapyon Adenoid Size: A Randomized, Prospective, Clinical Trial With Objective Data, Bi̇rgül Tuhani̇oğlu, Sanem Okşan Erkan Jan 2017

Evaluation Of The Effects Of Montelukast, Mometasone Furoate, And Combined Therapyon Adenoid Size: A Randomized, Prospective, Clinical Trial With Objective Data, Bi̇rgül Tuhani̇oğlu, Sanem Okşan Erkan

Turkish Journal of Medical Sciences

Background/aim: The incidence of adenoid hypertrophy is 2%-3% in children. Adenoidectomy is a commonly performed procedure in children that may cause complications such as early or late bleeding (4%-5%), recurrence of adenoid tissue (10%-20%), and postoperative respiratory problems (27%). Therefore, medical therapy alternatives to adenoidectomy are important and must be tried before surgery. In this study, we investigated the efficacy of mometasone furoate, montelukast, and a combination of these drugs in pediatric patients with adenoid hypertrophy who were scheduled for reduction with medical therapy after not being recommended for surgery.Materials and methods: The study included 120 children with adenoid hypertrophy …

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Expression Profiles Of Cd11b, Galectin-1, Beclin-1, And Caspase-3 In Nasal Polyposis, Alper Di̇lci̇, Nuray Varol, İlker Kiliçcioğlu, Ece Konac, Utku Aydi̇l, Yusuf Kizil, Süleyman Sabri̇ Uslu Jan 2017

Expression Profiles Of Cd11b, Galectin-1, Beclin-1, And Caspase-3 In Nasal Polyposis, Alper Di̇lci̇, Nuray Varol, İlker Kiliçcioğlu, Ece Konac, Utku Aydi̇l, Yusuf Kizil, Süleyman Sabri̇ Uslu

Turkish Journal of Medical Sciences

Background/aim: Nasal polyposis is a chronic inflammatory disease affecting the paranasal sinuses and nasal mucosae. It is thought that genetic and molecular mechanisms in inflammatory and apoptotic pathways are the main factors in the etiopathogenesis of nasal polyposis. The aim of this study was to investigate the expression patterns of CD11b, galectin-1, beclin-1, and caspase-3 in nasal polyps.Materials and methods: The mRNA expression levels of CD11b, galectin-1, beclin-1, and caspase-3 protein and western blot analysis of caspase-3 protein were evaluated in inferior turbinate mucosae and nasal polyp tissues.Results: CD11b expression was markedly higher in nasal polyp tissues when compared to …

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Pediatric Emergency Care Applied Research Network Head Injuryprediction Rules: On The Basis Of Cost And Effectiveness, Fatma Di̇lek Gökharman, Sonay Aydin, Erdem Fati̇hoğlu, Pinar Nerci̇s Koşar Jan 2017

Pediatric Emergency Care Applied Research Network Head Injuryprediction Rules: On The Basis Of Cost And Effectiveness, Fatma Di̇lek Gökharman, Sonay Aydin, Erdem Fati̇hoğlu, Pinar Nerci̇s Koşar

Turkish Journal of Medical Sciences

Background/aim: Head injuries are commonly seen in the pediatric population. Noncontrast enhanced cranial CT is the method of choice to detect possible traumatic brain injury (TBI). Concerns about ionizing radiation exposure make the evaluation more challenging. The aim of this study was to evaluate the effectiveness of the Pediatric Emergency Care Applied Research Network (PECARN) rules in predicting clinically important TBI and to determine the amount of medical resource waste and unnecessary radiation exposure.Materials and methods: This retrospective study included 1041 pediatric patients presented to the emergency department. The patients were divided into subgroups of "appropriate for cranial CT", "not …

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The Relationship Between Nonsuicidal Self-Injurious Behavior And Manners Of Death: A Multicenter Autopsy Study, Sai̇t Özsoy, Hacer Yaşar Teke, Hüseyi̇n Çeti̇n Ketenci̇, Ertuğrul Gök, Kenan Karbeyaz, Taner Akar, Hani̇fe Alkurt-Alkan, Mesut Akyol, Mehmet Ayhan Cöngöloğlu, Sermet Sezi̇gen, Ahmet Zahi̇t Dursun, Alper Özkök, Serhat Sari Jan 2017

The Relationship Between Nonsuicidal Self-Injurious Behavior And Manners Of Death: A Multicenter Autopsy Study, Sai̇t Özsoy, Hacer Yaşar Teke, Hüseyi̇n Çeti̇n Ketenci̇, Ertuğrul Gök, Kenan Karbeyaz, Taner Akar, Hani̇fe Alkurt-Alkan, Mesut Akyol, Mehmet Ayhan Cöngöloğlu, Sermet Sezi̇gen, Ahmet Zahi̇t Dursun, Alper Özkök, Serhat Sari

Turkish Journal of Medical Sciences

Background/aim: This study aimed to determine the relationship between nonsuicidal self-injurious behavior (NSSIB) and manners of death.Materials and methods: This study retrospectively evaluated 6604 autopsy cases evaluated at forensic medicine institutes of six major cities of Turkey. The study group consisted of all cases with NSSIB findings. The control group was created from cases without signs of NSSIB. Results: We found that the numbers of possible suicide and homicide cases in the NSSIB (+) group were significantly higher than in the NSSIB (-) group. The possibility of death due to suicide was 3.213 times and homicide was 2.004 times higher …

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Comparing The Effectiveness Of Ultrasound-Guided Versus Blind Steroid Injection In The Treatment Of Severe Carpal Tunnel Syndrome, Özgür Zeli̇ha Karaahmet, Eda Gürçay, Murat Kara, Azi̇ze Serçe, Zeynep Kiraç Ünal, Fatma Aytül Çakci Jan 2017

Comparing The Effectiveness Of Ultrasound-Guided Versus Blind Steroid Injection In The Treatment Of Severe Carpal Tunnel Syndrome, Özgür Zeli̇ha Karaahmet, Eda Gürçay, Murat Kara, Azi̇ze Serçe, Zeynep Kiraç Ünal, Fatma Aytül Çakci

Turkish Journal of Medical Sciences

Background/aim: This study aimed to compare the effectiveness of ultrasound (US)-guided injection versus blind injection of corticosteroids in the treatment of carpal tunnel syndrome (CTS). Materials and methods: This prospective, randomized clinical trial included patients with severe CTS based on clinical and electrophysiological criteria. The patients were evaluated for clinical and electrophysiological parameters at baseline and 4 weeks after treatment. Symptom severity and hand function were assessed by the Boston questionnaire. The patients underwent blind injection or US-guided injection. Results: When compared with baseline, both groups showed significant improvement in Boston questionnaire scores and all electrophysiological parameters. Significant differences were …

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